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Small Microbes Pathway Profiler |
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Small Microbes Pathway Profiler |
Sequence: MKGDDIMDA WHGFKRAEWC EEIDVRNFID ANYTPYEGDE SFLSQPSERT RKLWEKVSEL LKRERDNGGV LDVDTETIST ITSHKTGYID RELEIIVGIQ TDAPLKRSVM PFGGMRMVIK GAQAYGKDIS PDIVEIFTNF RKTHNDGVYD AYTPEMKRAK KAGIITGLPD AYGRGRIIGD YRRLPLYGAD RLIAEKEYEM VNLEFDYIDH ATVRNREEIA EQIRALKFLK EMALSYGYDI SMPAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRASIHT SSIQYESDDI MRHYWGDDYG IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG IAGLSVVTDS LSAIKYARVK PLRNENKIVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
PF02901: 19-607 ♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF01228: 623-729 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
Sequence: MKGDDIMDA WHGFKRAEWC EEIDVRNFID ANYTPYEGDE SFLSQPSERT RKLWEKVSEL LKRERDNGGV LDVDTETIST ITSHKTGYID RELEIIVGIQ TDAPLKRSVM PFGGMRMVIK GAQAYGKDIS PDIVEIFTNF RKTHNDGVYD AYTPEMKRAK KAGIITGLPD AYGRGRIIGD YRRLPLYGAD RLIAEKEYEM VNLEFDYIDH ATVRNREEIA EQIRALKFLK EMALSYGYDI SMPAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRASIHT SSIQYESDDI MRHYWGDDYG IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG IAGLSVVTDS LSAIKYARVK PLRNENKIVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI HMM: 291-399 TEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRASIHT SSIQYESDDI M ALI: 242-350 AKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RM ENV: 237-385 DI SMPAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRAS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MKGDDIMDA WHGFKRAEWC EEIDVRNFID ANYTPYEGDE SFLSQPSERT RKLWEKVSEL LKRERDNGGV LDVDTETIST ITSHKTGYID RELEIIVGIQ TDAPLKRSVM PFGGMRMVIK GAQAYGKDIS PDIVEIFTNF RKTHNDGVYD AYTPEMKRAK KAGIITGLPD AYGRGRIIGD YRRLPLYGAD RLIAEKEYEM VNLEFDYIDH ATVRNREEIA EQIRALKFLK EMALSYGYDI SMPAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRASIHT SSIQYESDDI MRHYWGDDYG IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG IAGLSVVTDS LSAIKYARVK PLRNENKIVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI HMM: 471-572 RFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG IAGLSVVTDS LSAIKYARVK PLRNENKIVV DYEVEGDYPK YGNNDARVDS IATN ALI: 408-510 G IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD RE ENV: 390-518 SIQYESDDI MRHYWGDDYG IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MKGDDIMDA WHGFKRAEWC EEIDVRNFID ANYTPYEGDE SFLSQPSERT RKLWEKVSEL LKRERDNGGV LDVDTETIST ITSHKTGYID RELEIIVGIQ TDAPLKRSVM PFGGMRMVIK GAQAYGKDIS PDIVEIFTNF RKTHNDGVYD AYTPEMKRAK KAGIITGLPD AYGRGRIIGD YRRLPLYGAD RLIAEKEYEM VNLEFDYIDH ATVRNREEIA EQIRALKFLK EMALSYGYDI SMPAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRASIHT SSIQYESDDI MRHYWGDDYG IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG IAGLSVVTDS LSAIKYARVK PLRNENKIVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI HMM: 644-832 IAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI ALI: 557-746 PK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEK ENV: 546-747 IVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MKGDDIMDA WHGFKRAEWC EEIDVRNFID ANYTPYEGDE SFLSQPSERT RKLWEKVSEL LKRERDNGGV LDVDTETIST ITSHKTGYID RELEIIVGIQ TDAPLKRSVM PFGGMRMVIK GAQAYGKDIS PDIVEIFTNF RKTHNDGVYD AYTPEMKRAK KAGIITGLPD AYGRGRIIGD YRRLPLYGAD RLIAEKEYEM VNLEFDYIDH ATVRNREEIA EQIRALKFLK EMALSYGYDI SMPAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRASIHT SSIQYESDDI MRHYWGDDYG IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG IAGLSVVTDS LSAIKYARVK PLRNENKIVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI HMM: 298-404 L IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRASIHT SSIQYESDDI MRHYWG ALI: 241-344 PAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVT ENV: 232-379 LSYGYDI SMPAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK R Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MKGDDIMDA WHGFKRAEWC EEIDVRNFID ANYTPYEGDE SFLSQPSERT RKLWEKVSEL LKRERDNGGV LDVDTETIST ITSHKTGYID RELEIIVGIQ TDAPLKRSVM PFGGMRMVIK GAQAYGKDIS PDIVEIFTNF RKTHNDGVYD AYTPEMKRAK KAGIITGLPD AYGRGRIIGD YRRLPLYGAD RLIAEKEYEM VNLEFDYIDH ATVRNREEIA EQIRALKFLK EMALSYGYDI SMPAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRASIHT SSIQYESDDI MRHYWGDDYG IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG IAGLSVVTDS LSAIKYARVK PLRNENKIVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI HMM: 509-580 REVLRTMACG IAGLSVVTDS LSAIKYARVK PLRNENKIVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DK ALI: 427-498 AR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS ENV: 398-520 I MRHYWGDDYG IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG IA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MKGDDIMDA WHGFKRAEWC EEIDVRNFID ANYTPYEGDE SFLSQPSERT RKLWEKVSEL LKRERDNGGV LDVDTETIST ITSHKTGYID RELEIIVGIQ TDAPLKRSVM PFGGMRMVIK GAQAYGKDIS PDIVEIFTNF RKTHNDGVYD AYTPEMKRAK KAGIITGLPD AYGRGRIIGD YRRLPLYGAD RLIAEKEYEM VNLEFDYIDH ATVRNREEIA EQIRALKFLK EMALSYGYDI SMPAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRASIHT SSIQYESDDI MRHYWGDDYG IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG IAGLSVVTDS LSAIKYARVK PLRNENKIVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI HMM: 662-846 VIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI ALI: 557-743 PK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTI ENV: 543-747 ENKIVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MKGDDIMDA WHGFKRAEWC EEIDVRNFID ANYTPYEGDE SFLSQPSERT RKLWEKVSEL LKRERDNGGV LDVDTETIST ITSHKTGYID RELEIIVGIQ TDAPLKRSVM PFGGMRMVIK GAQAYGKDIS PDIVEIFTNF RKTHNDGVYD AYTPEMKRAK KAGIITGLPD AYGRGRIIGD YRRLPLYGAD RLIAEKEYEM VNLEFDYIDH ATVRNREEIA EQIRALKFLK EMALSYGYDI SMPAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRASIHT SSIQYESDDI MRHYWGDDYG IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG IAGLSVVTDS LSAIKYARVK PLRNENKIVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI HMM: 76-106 IST ITSHKTGYID RELEIIVGIQ TDAPLKRS ALI: 87-118 ID RELEIIVGIQ TDAPLKRSVM PFGGMRMVIK ENV: 77-131 ST ITSHKTGYID RELEIIVGIQ TDAPLKRSVM PFGGMRMVIK GAQAYGKDIS PDI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MKGDDIMDA WHGFKRAEWC EEIDVRNFID ANYTPYEGDE SFLSQPSERT RKLWEKVSEL LKRERDNGGV LDVDTETIST ITSHKTGYID RELEIIVGIQ TDAPLKRSVM PFGGMRMVIK GAQAYGKDIS PDIVEIFTNF RKTHNDGVYD AYTPEMKRAK KAGIITGLPD AYGRGRIIGD YRRLPLYGAD RLIAEKEYEM VNLEFDYIDH ATVRNREEIA EQIRALKFLK EMALSYGYDI SMPAKDSKEA VQWLYFAYLG AIKEQNGAAM SLGRVSTFLD IYFERDLNEG KITEEQVQEL IDQLVIKLRL VRFLRTPDYE KLFSGDPTWV TESIGGMSLD GRTLVTKSSF RMLNTLFNLG PSPEPNLTVL WSVNLPDGFK RFCSRASIHT SSIQYESDDI MRHYWGDDYG IACCVSAMRM GKQMQFFGAR CNLAKALLYA INGGRDEITG NQVAPMFAEV DTEYLDYDDV MKRFDMVLDW VARLYMNTLN IIHYMHDKYS YERLQMAFHD REVLRTMACG IAGLSVVTDS LSAIKYARVK PLRNENKIVV DYEVEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI HMM: 633-818 DIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI ALI: 557-744 PK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIH ENV: 552-747 VEGDYPK YGNNDARVDS IATNIVKIFM DKLRKQRTYR NSTPTLSILT ITSNVVYGEK TGNTPDGRKK GEPLAPGANP MHGRDIKGAL AVLSSIAKLP YEYAQDGISY TFSVIPKALG REEEARVNNL TALLDGYFKE GGHHININVF EKETLLDAME HPEKYPQLTI RVSGYAVNFI KLTREQQLDV INRTIHEKI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MSEKQLGNF KSGIWQDRVD VRDFIIKNYT PYDGCEEFLV ESSIKTKKLW SKCKKLLREE YTKNGVLNVD TKTVAGIISH SAGYIDEKYE VIKGLQTDKP LKRAVMPFGG IRMAKQSCEQ YGYTLSPKIE ETFKKYRKTH NDGVFSAYTD DMKMARKCGV ITGLPDAYGR GRIIGDYRRV ALYGIEKLIR DKKNDLSKIL DMDMTEENIR LREEVSEQIT ALNELSLMGK EYGYDLTKPA QNSFEAIQWT YFAFLGSIKE TNGAANSLGR VSTFFDVYIK RDMDKGILSE VEAQELIDQF VIKLRLVRHL RTPDYNDLFA GDPVWITESI GGMCEDGRHM VTKTSFRFLQ TLFNLGPSPE PNITILWSER LPQNFKRFCA KVSMVTSAIQ YENDDLMRSH FNDDYSISCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE RLMAFGVAGL SVLADSLSAI KYTYVKAIRD ERGLITDFEI KGDYPQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGAM
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
PF02901: 15-603 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF01228: 618-725 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MSEKQLGNF KSGIWQDRVD VRDFIIKNYT PYDGCEEFLV ESSIKTKKLW SKCKKLLREE YTKNGVLNVD TKTVAGIISH SAGYIDEKYE VIKGLQTDKP LKRAVMPFGG IRMAKQSCEQ YGYTLSPKIE ETFKKYRKTH NDGVFSAYTD DMKMARKCGV ITGLPDAYGR GRIIGDYRRV ALYGIEKLIR DKKNDLSKIL DMDMTEENIR LREEVSEQIT ALNELSLMGK EYGYDLTKPA QNSFEAIQWT YFAFLGSIKE TNGAANSLGR VSTFFDVYIK RDMDKGILSE VEAQELIDQF VIKLRLVRHL RTPDYNDLFA GDPVWITESI GGMCEDGRHM VTKTSFRFLQ TLFNLGPSPE PNITILWSER LPQNFKRFCA KVSMVTSAIQ YENDDLMRSH FNDDYSISCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE RLMAFGVAGL SVLADSLSAI KYTYVKAIRD ERGLITDFEI KGDYPQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGAM HMM: 290-576 EAQELIDQF VIKLRLVRHL RTPDYNDLFA GDPVWITESI GGMCEDGRHM VTKTSFRFLQ TLFNLGPSPE PNITILWSER LPQNFKRFCA KVSMVTSAIQ YENDDLMRSH FNDDYSISCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE RLMAFGVAGL SVLADSLSAI KYTYVKAIRD ERGLITDFEI KGDYPQFGNG DDRVDNIAID IVRDFYTD ALI: 237-510 PA QNSFEAIQWT YFAFLGSIKE TNGAANSLGR VSTFFDVYIK RDMDKGILSE VEAQELIDQF VIKLRLVRHL RTPDYNDLFA GDPVWITESI GGMCEDGRHM VTKTSFRFLQ TLFNLGPSPE PNITILWSER LPQNFKRFCA KVSMVTSAIQ YENDDLMRSH FNDDYSISCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE RL ENV: 222-517 ELSLMGK EYGYDLTKPA QNSFEAIQWT YFAFLGSIKE TNGAANSLGR VSTFFDVYIK RDMDKGILSE VEAQELIDQF VIKLRLVRHL RTPDYNDLFA GDPVWITESI GGMCEDGRHM VTKTSFRFLQ TLFNLGPSPE PNITILWSER LPQNFKRFCA KVSMVTSAIQ YENDDLMRSH FNDDYSISCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE RLMAFGVAG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MSEKQLGNF KSGIWQDRVD VRDFIIKNYT PYDGCEEFLV ESSIKTKKLW SKCKKLLREE YTKNGVLNVD TKTVAGIISH SAGYIDEKYE VIKGLQTDKP LKRAVMPFGG IRMAKQSCEQ YGYTLSPKIE ETFKKYRKTH NDGVFSAYTD DMKMARKCGV ITGLPDAYGR GRIIGDYRRV ALYGIEKLIR DKKNDLSKIL DMDMTEENIR LREEVSEQIT ALNELSLMGK EYGYDLTKPA QNSFEAIQWT YFAFLGSIKE TNGAANSLGR VSTFFDVYIK RDMDKGILSE VEAQELIDQF VIKLRLVRHL RTPDYNDLFA GDPVWITESI GGMCEDGRHM VTKTSFRFLQ TLFNLGPSPE PNITILWSER LPQNFKRFCA KVSMVTSAIQ YENDDLMRSH FNDDYSISCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE RLMAFGVAGL SVLADSLSAI KYTYVKAIRD ERGLITDFEI KGDYPQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGAM HMM: 644-831 PYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGAM ALI: 553-741 PQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHG ENV: 544-743 TDFEI KGDYPQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGAM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MSEKQLGNF KSGIWQDRVD VRDFIIKNYT PYDGCEEFLV ESSIKTKKLW SKCKKLLREE YTKNGVLNVD TKTVAGIISH SAGYIDEKYE VIKGLQTDKP LKRAVMPFGG IRMAKQSCEQ YGYTLSPKIE ETFKKYRKTH NDGVFSAYTD DMKMARKCGV ITGLPDAYGR GRIIGDYRRV ALYGIEKLIR DKKNDLSKIL DMDMTEENIR LREEVSEQIT ALNELSLMGK EYGYDLTKPA QNSFEAIQWT YFAFLGSIKE TNGAANSLGR VSTFFDVYIK RDMDKGILSE VEAQELIDQF VIKLRLVRHL RTPDYNDLFA GDPVWITESI GGMCEDGRHM VTKTSFRFLQ TLFNLGPSPE PNITILWSER LPQNFKRFCA KVSMVTSAIQ YENDDLMRSH FNDDYSISCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE RLMAFGVAGL SVLADSLSAI KYTYVKAIRD ERGLITDFEI KGDYPQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGAM HMM: 491-595 DKYAYERL MMALHDTEVE RLMAFGVAGL SVLADSLSAI KYTYVKAIRD ERGLITDFEI KGDYPQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTI ALI: 406-509 SCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE R ENV: 234-524 LTKPA QNSFEAIQWT YFAFLGSIKE TNGAANSLGR VSTFFDVYIK RDMDKGILSE VEAQELIDQF VIKLRLVRHL RTPDYNDLFA GDPVWITESI GGMCEDGRHM VTKTSFRFLQ TLFNLGPSPE PNITILWSER LPQNFKRFCA KVSMVTSAIQ YENDDLMRSH FNDDYSISCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE RLMAFGVAGL SVLADS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MSEKQLGNF KSGIWQDRVD VRDFIIKNYT PYDGCEEFLV ESSIKTKKLW SKCKKLLREE YTKNGVLNVD TKTVAGIISH SAGYIDEKYE VIKGLQTDKP LKRAVMPFGG IRMAKQSCEQ YGYTLSPKIE ETFKKYRKTH NDGVFSAYTD DMKMARKCGV ITGLPDAYGR GRIIGDYRRV ALYGIEKLIR DKKNDLSKIL DMDMTEENIR LREEVSEQIT ALNELSLMGK EYGYDLTKPA QNSFEAIQWT YFAFLGSIKE TNGAANSLGR VSTFFDVYIK RDMDKGILSE VEAQELIDQF VIKLRLVRHL RTPDYNDLFA GDPVWITESI GGMCEDGRHM VTKTSFRFLQ TLFNLGPSPE PNITILWSER LPQNFKRFCA KVSMVTSAIQ YENDDLMRSH FNDDYSISCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE RLMAFGVAGL SVLADSLSAI KYTYVKAIRD ERGLITDFEI KGDYPQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGAM HMM: 662-846 SLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGAM ALI: 553-739 PQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT F ENV: 530-743 YTYVKAIRD ERGLITDFEI KGDYPQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGAM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MSEKQLGNF KSGIWQDRVD VRDFIIKNYT PYDGCEEFLV ESSIKTKKLW SKCKKLLREE YTKNGVLNVD TKTVAGIISH SAGYIDEKYE VIKGLQTDKP LKRAVMPFGG IRMAKQSCEQ YGYTLSPKIE ETFKKYRKTH NDGVFSAYTD DMKMARKCGV ITGLPDAYGR GRIIGDYRRV ALYGIEKLIR DKKNDLSKIL DMDMTEENIR LREEVSEQIT ALNELSLMGK EYGYDLTKPA QNSFEAIQWT YFAFLGSIKE TNGAANSLGR VSTFFDVYIK RDMDKGILSE VEAQELIDQF VIKLRLVRHL RTPDYNDLFA GDPVWITESI GGMCEDGRHM VTKTSFRFLQ TLFNLGPSPE PNITILWSER LPQNFKRFCA KVSMVTSAIQ YENDDLMRSH FNDDYSISCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE RLMAFGVAGL SVLADSLSAI KYTYVKAIRD ERGLITDFEI KGDYPQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGAM HMM: 633-817 ALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGAM ALI: 553-739 PQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT F ENV: 282-742 DKGILSE VEAQELIDQF VIKLRLVRHL RTPDYNDLFA GDPVWITESI GGMCEDGRHM VTKTSFRFLQ TLFNLGPSPE PNITILWSER LPQNFKRFCA KVSMVTSAIQ YENDDLMRSH FNDDYSISCC VSGMRTGKDM QYFGARCNLP KLLLLALNGG KDEITGEQIA PEIEPYPYEY LDYEKVISRF KQMQKWLTRL YVNTMNVIHF MHDKYAYERL MMALHDTEVE RLMAFGVAGL SVLADSLSAI KYTYVKAIRD ERGLITDFEI KGDYPQFGNG DDRVDNIAID IVRDFYTDLK KCTAYRNAKH TLSILTITSN VVYGKKTGST PDGRKIGDPF APGANPMHGR DKLGALAALN SVAKIPYEYC KDGISLTLTL VPSSLGRDTN SRLNNLVALL DGYFIQRGHH ININVLERVV LERAMKDPYN YPQLTIRVSG YAVNFIRLTP QQQEEVISRT FHGA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MFTDRIILQ NGKYKDIIWK VLGIIEMENP TVKYGMIIDL DKCIGCYACQ VNCQKEHNLS CGEDRLKVHT QDFGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTEGW ENFKQDFLAQ ARQRDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL RECPGLRNIG QPLPYPRYPE GALIKGLPKN PNVYFEGKLI RQGEELTVEW LRRNGGRAAW PASYYRYRRN KEVKPSGYLP LTDSRKFEFN YHYVNELNKK MKCGYPASFL WKENNRQFAE SLKKEYPFHL ITGRTHQTGT MTQVCISLSN LETEANKKMN DTFAISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYLRGKAF LSSGIKSGVI KTTFGSGGRE ATGIGFFSGA VSFTPNINRL YDSNAINQIT GMPAFGDVMV KIEKEPEEGR MNDG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110
PF13247: 80-174 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌
PF04879: 256-302 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF00384: 304-789 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
Sequence: MFTDRIILQ NGKYKDIIWK VLGIIEMENP TVKYGMIIDL DKCIGCYACQ VNCQKEHNLS CGEDRLKVHT QDFGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTEGW ENFKQDFLAQ ARQRDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL RECPGLRNIG QPLPYPRYPE GALIKGLPKN PNVYFEGKLI RQGEELTVEW LRRNGGRAAW PASYYRYRRN KEVKPSGYLP LTDSRKFEFN YHYVNELNKK MKCGYPASFL WKENNRQFAE SLKKEYPFHL ITGRTHQTGT MTQVCISLSN LETEANKKMN DTFAISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYLRGKAF LSSGIKSGVI KTTFGSGGRE ATGIGFFSGA VSFTPNINRL YDSNAINQIT GMPAFGDVMV KIEKEPEEGR MNDG HMM: 71-296 FGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGL ALI: 260-494 ECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILT ENV: 239-516 KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110
Sequence: MFTDRIILQ NGKYKDIIWK VLGIIEMENP TVKYGMIIDL DKCIGCYACQ VNCQKEHNLS CGEDRLKVHT QDFGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTEGW ENFKQDFLAQ ARQRDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL RECPGLRNIG QPLPYPRYPE GALIKGLPKN PNVYFEGKLI RQGEELTVEW LRRNGGRAAW PASYYRYRRN KEVKPSGYLP LTDSRKFEFN YHYVNELNKK MKCGYPASFL WKENNRQFAE SLKKEYPFHL ITGRTHQTGT MTQVCISLSN LETEANKKMN DTFAISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYLRGKAF LSSGIKSGVI KTTFGSGGRE ATGIGFFSGA VSFTPNINRL YDSNAINQIT GMPAFGDVMV KIEKEPEEGR MNDG HMM: 612-677 GSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLK ALI: 723-788 NTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA ENV: 712-796 FTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110
Sequence: MFTDRIILQ NGKYKDIIWK VLGIIEMENP TVKYGMIIDL DKCIGCYACQ VNCQKEHNLS CGEDRLKVHT QDFGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTEGW ENFKQDFLAQ ARQRDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL RECPGLRNIG QPLPYPRYPE GALIKGLPKN PNVYFEGKLI RQGEELTVEW LRRNGGRAAW PASYYRYRRN KEVKPSGYLP LTDSRKFEFN YHYVNELNKK MKCGYPASFL WKENNRQFAE SLKKEYPFHL ITGRTHQTGT MTQVCISLSN LETEANKKMN DTFAISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYLRGKAF LSSGIKSGVI KTTFGSGGRE ATGIGFFSGA VSFTPNINRL YDSNAINQIT GMPAFGDVMV KIEKEPEEGR MNDG HMM: 88-190 H CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RS ALI: 258-353 P AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCG ENV: 251-359 NTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV E Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110
Sequence: MFTDRIILQ NGKYKDIIWK VLGIIEMENP TVKYGMIIDL DKCIGCYACQ VNCQKEHNLS CGEDRLKVHT QDFGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTEGW ENFKQDFLAQ ARQRDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL RECPGLRNIG QPLPYPRYPE GALIKGLPKN PNVYFEGKLI RQGEELTVEW LRRNGGRAAW PASYYRYRRN KEVKPSGYLP LTDSRKFEFN YHYVNELNKK MKCGYPASFL WKENNRQFAE SLKKEYPFHL ITGRTHQTGT MTQVCISLSN LETEANKKMN DTFAISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYLRGKAF LSSGIKSGVI KTTFGSGGRE ATGIGFFSGA VSFTPNINRL YDSNAINQIT GMPAFGDVMV KIEKEPEEGR MNDG HMM: 278-307 N PESLNNQGTV CAKGAAGLEL VYSPLRIKK ALI: 457-486 VV IDPAFTNSAA KANLWLPIVP GTDSELLA ENV: 450-512 LTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110
Sequence: MFTDRIILQ NGKYKDIIWK VLGIIEMENP TVKYGMIIDL DKCIGCYACQ VNCQKEHNLS CGEDRLKVHT QDFGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTEGW ENFKQDFLAQ ARQRDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL RECPGLRNIG QPLPYPRYPE GALIKGLPKN PNVYFEGKLI RQGEELTVEW LRRNGGRAAW PASYYRYRRN KEVKPSGYLP LTDSRKFEFN YHYVNELNKK MKCGYPASFL WKENNRQFAE SLKKEYPFHL ITGRTHQTGT MTQVCISLSN LETEANKKMN DTFAISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYLRGKAF LSSGIKSGVI KTTFGSGGRE ATGIGFFSGA VSFTPNINRL YDSNAINQIT GMPAFGDVMV KIEKEPEEGR MNDG HMM: 413-477 KLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIV ALI: 542-608 SPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL ENV: 532-625 RDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110
Sequence: MFTDRIILQ NGKYKDIIWK VLGIIEMENP TVKYGMIIDL DKCIGCYACQ VNCQKEHNLS CGEDRLKVHT QDFGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTEGW ENFKQDFLAQ ARQRDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL RECPGLRNIG QPLPYPRYPE GALIKGLPKN PNVYFEGKLI RQGEELTVEW LRRNGGRAAW PASYYRYRRN KEVKPSGYLP LTDSRKFEFN YHYVNELNKK MKCGYPASFL WKENNRQFAE SLKKEYPFHL ITGRTHQTGT MTQVCISLSN LETEANKKMN DTFAISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYLRGKAF LSSGIKSGVI KTTFGSGGRE ATGIGFFSGA VSFTPNINRL YDSNAINQIT GMPAFGDVMV KIEKEPEEGR MNDG HMM: 630-699 KITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP V ALI: 723-792 NTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALV ENV: 720-809 YLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ T Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110
Sequence: MFTDRIILQ NGKYKDIIWK VLGIIEMENP TVKYGMIIDL DKCIGCYACQ VNCQKEHNLS CGEDRLKVHT QDFGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTEGW ENFKQDFLAQ ARQRDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL RECPGLRNIG QPLPYPRYPE GALIKGLPKN PNVYFEGKLI RQGEELTVEW LRRNGGRAAW PASYYRYRRN KEVKPSGYLP LTDSRKFEFN YHYVNELNKK MKCGYPASFL WKENNRQFAE SLKKEYPFHL ITGRTHQTGT MTQVCISLSN LETEANKKMN DTFAISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYLRGKAF LSSGIKSGVI KTTFGSGGRE ATGIGFFSGA VSFTPNINRL YDSNAINQIT GMPAFGDVMV KIEKEPEEGR MNDG HMM: 866-896 VEW LRRNGGRAAW PASYYRYRRN KEVKPSGY ALI: 997-1027 AN TIAIPVFLIN EEDGNKLGLY TGEMIRLVI ENV: 982-1033 AISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110
Sequence: MFTDRIILQ NGKYKDIIWK VLGIIEMENP TVKYGMIIDL DKCIGCYACQ VNCQKEHNLS CGEDRLKVHT QDFGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTEGW ENFKQDFLAQ ARQRDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL RECPGLRNIG QPLPYPRYPE GALIKGLPKN PNVYFEGKLI RQGEELTVEW LRRNGGRAAW PASYYRYRRN KEVKPSGYLP LTDSRKFEFN YHYVNELNKK MKCGYPASFL WKENNRQFAE SLKKEYPFHL ITGRTHQTGT MTQVCISLSN LETEANKKMN DTFAISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYLRGKAF LSSGIKSGVI KTTFGSGGRE ATGIGFFSGA VSFTPNINRL YDSNAINQIT GMPAFGDVMV KIEKEPEEGR MNDG HMM: 73-301 TYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYS ALI: 259-496 AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHD ENV: 221-511 ADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110
Sequence: MFTDRIILQ NGKYKDIIWK VLGIIEMENP TVKYGMIIDL DKCIGCYACQ VNCQKEHNLS CGEDRLKVHT QDFGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTEGW ENFKQDFLAQ ARQRDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL RECPGLRNIG QPLPYPRYPE GALIKGLPKN PNVYFEGKLI RQGEELTVEW LRRNGGRAAW PASYYRYRRN KEVKPSGYLP LTDSRKFEFN YHYVNELNKK MKCGYPASFL WKENNRQFAE SLKKEYPFHL ITGRTHQTGT MTQVCISLSN LETEANKKMN DTFAISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYLRGKAF LSSGIKSGVI KTTFGSGGRE ATGIGFFSGA VSFTPNINRL YDSNAINQIT GMPAFGDVMV KIEKEPEEGR MNDG HMM: 398-462 L PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPA ALI: 542-607 SPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGG ENV: 534-651 ETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110
Sequence: MFTDRIILQ NGKYKDIIWK VLGIIEMENP TVKYGMIIDL DKCIGCYACQ VNCQKEHNLS CGEDRLKVHT QDFGTYPALT RLFLPVLCNH CEKPTCTEYC DRNALYYTEQ GIIRYDSETC NRCLACLEAC SCGAIGYQNE ASLLSKCDFC FERLQQGLKP TCVLGCMSKA LHFGELNHKE SGIIPVLQAY RSFLYVQKTL ASFLPKVFFL QRGNNRYPLL TKADLSLYNF QFTDSENFDF KDGKQAFMKN CINTVDLMCP AECSISVFVE GGMARKIYGN PESLNNQGTV CAKGAAGLEL VYSPLRIKKP LVRIGERGEE KWQEVSWESA LKQIAEKLLV IKAKYGAESV VLDCGDLTDV EPYMMLFHAF GTPHTYTHSA ICDTNRRWGS KLLMGDERPL PDIQRPIMLN NYDNKLYFKS GHDTKLLINL GSNPLVATRF NYMSRGIPAA QLTNEMYYVV IDPAFTNSAA KANLWLPIVP GTDSELLASM LFYILTHDEP EKKQTSFIDH DFIENYTEGW ENFKQDFLAQ ARQRDETNGL LYFSPEWGAD KTGIASDQII RLAHLMGITK PAAIEIGMHG GSHHLAGDLT STLANVICAI TGNIDVPGGL VFTGSVKPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHTYPI KAFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL RECPGLRNIG QPLPYPRYPE GALIKGLPKN PNVYFEGKLI RQGEELTVEW LRRNGGRAAW PASYYRYRRN KEVKPSGYLP LTDSRKFEFN YHYVNELNKK MKCGYPASFL WKENNRQFAE SLKKEYPFHL ITGRTHQTGT MTQVCISLSN LETEANKKMN DTFAISAHTQ NKDKGKFEAN TIAIPVFLIN EEDGNKLGLY TGEMIRLVIA NGKYLRGKAF LSSGIKSGVI KTTFGSGGRE ATGIGFFSGA VSFTPNINRL YDSNAINQIT GMPAFGDVMV KIEKEPEEGR MNDG HMM: 615-685 KPSL DLISRKINGD GKITRIVAGE VRHGTYQQLH KDLYGDYPFA WKGVLSTIPR NILDDVTLKR GPFNGHT ALI: 723-793 NTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVI ENV: 690-821 AFVNRTGNP VYTGGNTEEW IKAFTATKDG EYLLNTIVHI DTHINETGKY ADFILPECSY LEKMGLSDQY TINPEIALRE RVIAPQHESK APFWIMQKLA GALVIAGDKD INESSFTCYQ TEEDLLNTQL REC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110
Sequence: MNSELDYLR ENLKCIMNKI EKAATKSGRK PDDITIVAVT KTIEPDKIMA IIDLGLIELG ENRVQELAKK YDIINRKCNW HHIGNLQTNK VKYIVDKVKL IHSVDRIELA QEIQKKAEKY GRIIDILIQV NVSLEETKSG VFEENLIELI NKISVFENIK IKGLMTLAPY DENPEKVRDV FRKLRNLSID IEQKNLDNVS MEFLSMGMSN DYEVAIEEGA NIVRIGTALF GRRS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230
PF01168: 7-232 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MNSELDYLR ENLKCIMNKI EKAATKSGRK PDDITIVAVT KTIEPDKIMA IIDLGLIELG ENRVQELAKK YDIINRKCNW HHIGNLQTNK VKYIVDKVKL IHSVDRIELA QEIQKKAEKY GRIIDILIQV NVSLEETKSG VFEENLIELI NKISVFENIK IKGLMTLAPY DENPEKVRDV FRKLRNLSID IEQKNLDNVS MEFLSMGMSN DYEVAIEEGA NIVRIGTALF GRRS HMM: 253-285 ALI: 10-42 NLKCIMNKI EKAATKSGRK PDDITIVAVT KTIE ENV: 7-49 LR ENLKCIMNKI EKAATKSGRK PDDITIVAVT KTIEPDKIMA I Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230
Sequence: MNSELDYLR ENLKCIMNKI EKAATKSGRK PDDITIVAVT KTIEPDKIMA IIDLGLIELG ENRVQELAKK YDIINRKCNW HHIGNLQTNK VKYIVDKVKL IHSVDRIELA QEIQKKAEKY GRIIDILIQV NVSLEETKSG VFEENLIELI NKISVFENIK IKGLMTLAPY DENPEKVRDV FRKLRNLSID IEQKNLDNVS MEFLSMGMSN DYEVAIEEGA NIVRIGTALF GRRS HMM: 258-289 ALI: 108-136 A QEIQKKAEKY GRIIDILIQV NVSLEETK ENV: 97-157 KL IHSVDRIELA QEIQKKAEKY GRIIDILIQV NVSLEETKSG VFEENLIELI NKISVFENI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230
Sequence: MDKYICTVC GYIYDPTEGD PDSGVAPGTS FEEIPDDWVC PMCGVGKDMF EKA
10 20 30 40 50
PF00301: 2-49 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MDKYICTVC GYIYDPTEGD PDSGVAPGTS FEEIPDDWVC PMCGVGKDMF EKA HMM: 425-469 ALI: 3-47 YICTVC GYIYDPTEGD PDSGVAPGTS FEEIPDDWVC PMCGVGKDM ENV: 1-52 DKYICTVC GYIYDPTEGD PDSGVAPGTS FEEIPDDWVC PMCGVGKDMF EKA Position: 10 20 30 40 50
No PFAM domains
Sequence: MSIKPIDFQ VLIPKTGEVA KIQNDQQNKN NAMQQQQTAM NQNKAQDNVN LVHSQENSQK AAIKDKQQKN SSKKNKKDNK KSKCENKNDP MTSTIDIKL HMM: 359-432 ALI: 7-84 FQ VLIPKTGEVA KIQNDQQNKN NAMQQQQTAM NQNKAQDNVN LVHSQENSQK AAIKDKQQKN SSKKNKKDNK KSKCEN ENV: 3-96 KPIDFQ VLIPKTGEVA KIQNDQQNKN NAMQQQQTAM NQNKAQDNVN LVHSQENSQK AAIKDKQQKN SSKKNKKDNK KSKCENKNDP MTSTIDIK Position: 10 20 30 40 50 60 70 80 90
Sequence: MSENILYSN SNDFENDVLK SHLPVVVYFY SDDCPPCSAF APIFERSQEK YSDQMKFVKI YRQQNRQLAE SLNVKSSPTL LFYRDGKEVC SRLNGYISNP EFKKSIERVI GGFCVRADRK KVHCDVLILG GGAAGLSAAI YTSRAKLYTV VVDEGLTGGQ VASTFHVANY PGTNGVVRGI DLMENMRKQA EDFGTTIDDM MEISQADFEG EDKFISTEDT DYYAKAIIIA TGATPRKLPA EGEREFRGRG VHYCATCDGA MYQDANVLVI GGGNSATEEA VFLTRYVKHV TIVHHLDHFQ ATKGAQEEVF KNPNISVMWD CQVKKVIGEN FVKGAIIENV KTKETTEIET DALFVYIGME PKTELFKDKI ELNEYGYIIT DEDMKTNVPG VFAAGDVRDK NVRQIATATG DGVIASITVE KFISGR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
PF00085: 6-105 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF07992: 123-409 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
Sequence: MSENILYSN SNDFENDVLK SHLPVVVYFY SDDCPPCSAF APIFERSQEK YSDQMKFVKI YRQQNRQLAE SLNVKSSPTL LFYRDGKEVC SRLNGYISNP EFKKSIERVI GGFCVRADRK KVHCDVLILG GGAAGLSAAI YTSRAKLYTV VVDEGLTGGQ VASTFHVANY PGTNGVVRGI DLMENMRKQA EDFGTTIDDM MEISQADFEG EDKFISTEDT DYYAKAIIIA TGATPRKLPA EGEREFRGRG VHYCATCDGA MYQDANVLVI GGGNSATEEA VFLTRYVKHV TIVHHLDHFQ ATKGAQEEVF KNPNISVMWD CQVKKVIGEN FVKGAIIENV KTKETTEIET DALFVYIGME PKTELFKDKI ELNEYGYIIT DEDMKTNVPG VFAAGDVRDK NVRQIATATG DGVIASITVE KFISGR HMM: 2-54 ENILYSN SNDFENDVLK SHLPVVVYFY SDDCPPCSAF APIFERSQEK YSDQMK ALI: 119-172 KVHCDVLILG GGAAGLSAAI YTSRAKLYTV VVDEGLTGGQ VASTFHVANY PGTN ENV: 118-191 K KVHCDVLILG GGAAGLSAAI YTSRAKLYTV VVDEGLTGGQ VASTFHVANY PGTNGVVRGI DLMENMRKQA EDF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
Sequence: MSENILYSN SNDFENDVLK SHLPVVVYFY SDDCPPCSAF APIFERSQEK YSDQMKFVKI YRQQNRQLAE SLNVKSSPTL LFYRDGKEVC SRLNGYISNP EFKKSIERVI GGFCVRADRK KVHCDVLILG GGAAGLSAAI YTSRAKLYTV VVDEGLTGGQ VASTFHVANY PGTNGVVRGI DLMENMRKQA EDFGTTIDDM MEISQADFEG EDKFISTEDT DYYAKAIIIA TGATPRKLPA EGEREFRGRG VHYCATCDGA MYQDANVLVI GGGNSATEEA VFLTRYVKHV TIVHHLDHFQ ATKGAQEEVF KNPNISVMWD CQVKKVIGEN FVKGAIIENV KTKETTEIET DALFVYIGME PKTELFKDKI ELNEYGYIIT DEDMKTNVPG VFAAGDVRDK NVRQIATATG DGVIASITVE KFISGR HMM: 155-225 TGGQ VASTFHVANY PGTNGVVRGI DLMENMRKQA EDFGTTIDDM MEISQADFEG EDKFISTEDT DYYAKAI ALI: 240-310 GEREFRGRG VHYCATCDGA MYQDANVLVI GGGNSATEEA VFLTRYVKHV TIVHHLDHFQ ATKGAQEEVF KN ENV: 195-325 IDDM MEISQADFEG EDKFISTEDT DYYAKAIIIA TGATPRKLPA EGEREFRGRG VHYCATCDGA MYQDANVLVI GGGNSATEEA VFLTRYVKHV TIVHHLDHFQ ATKGAQEEVF KNPNISVMWD CQVKKVI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
Sequence: MEKYVCTAC GYIYDPEKGD PDGGIAPGTA FEDIPDDWVC PICGVGKDMF EKE
10 20 30 40 50
PF00301: 2-49 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MEKYVCTAC GYIYDPEKGD PDGGIAPGTA FEDIPDDWVC PICGVGKDMF EKE HMM: 424-469 ALI: 2-47 KYVCTAC GYIYDPEKGD PDGGIAPGTA FEDIPDDWVC PICGVGKDM ENV: 1-52 EKYVCTAC GYIYDPEKGD PDGGIAPGTA FEDIPDDWVC PICGVGKDMF EKE Position: 10 20 30 40 50
Sequence: MDDGYKHPS HEKKMKFRIN ILGSKNGNIR WIVLITILAF VLSSSLSFVS SNLLGDVNIF FSILIVLVIV FIGIIFDIIG IAVTSADESP FHAMASRKYY GAKQAIRLIR NANKVSSFCN DVVGDICGVI SGTASAFIVF KVSQSVGGIV AFLVELSFAG FVAALTIGGK AIGKTIAIEN CDYIVYKVGV IAKFLTGRFG IKKKKRKHKN RQMTNKKFKQ NGQKSDDRKT NKNKNKQNKK DTV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240
Sequence: MDDGYKHPS HEKKMKFRIN ILGSKNGNIR WIVLITILAF VLSSSLSFVS SNLLGDVNIF FSILIVLVIV FIGIIFDIIG IAVTSADESP FHAMASRKYY GAKQAIRLIR NANKVSSFCN DVVGDICGVI SGTASAFIVF KVSQSVGGIV AFLVELSFAG FVAALTIGGK AIGKTIAIEN CDYIVYKVGV IAKFLTGRFG IKKKKRKHKN RQMTNKKFKQ NGQKSDDRKT NKNKNKQNKK DTV HMM: 20-91 LGSKNGNIR WIVLITILAF VLSSSLSFVS SNLLGDVNIF FSILIVLVIV FIGIIFDIIG IAVTSADESP FHA ALI: 30-101 IVLITILAF VLSSSLSFVS SNLLGDVNIF FSILIVLVIV FIGIIFDIIG IAVTSADESP FHAMASRKYY GAK ENV: 23-155 KNGNIR WIVLITILAF VLSSSLSFVS SNLLGDVNIF FSILIVLVIV FIGIIFDIIG IAVTSADESP FHAMASRKYY GAKQAIRLIR NANKVSSFCN DVVGDICGVI SGTASAFIVF KVSQSVGGIV AFLVELS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240
Sequence: MDDGYKHPS HEKKMKFRIN ILGSKNGNIR WIVLITILAF VLSSSLSFVS SNLLGDVNIF FSILIVLVIV FIGIIFDIIG IAVTSADESP FHAMASRKYY GAKQAIRLIR NANKVSSFCN DVVGDICGVI SGTASAFIVF KVSQSVGGIV AFLVELSFAG FVAALTIGGK AIGKTIAIEN CDYIVYKVGV IAKFLTGRFG IKKKKRKHKN RQMTNKKFKQ NGQKSDDRKT NKNKNKQNKK DTV HMM: 377-410 ALI: 202-235 KKRKHKN RQMTNKKFKQ NGQKSDDRKT NKNKNKQ ENV: 191-242 KFLTGRFG IKKKKRKHKN RQMTNKKFKQ NGQKSDDRKT NKNKNKQNKK DTV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240
Sequence: MNDAIVKST MENFDKDVLK SDIPVAVLFY TESCPVCDAF MPIFERTAQK YGKYMKFVKI YRQQNRQLVE DLKIKSSPTV LFYKEGNEVC TRLNGYISNA EFVEAIERVI GDVCKGEKRE KVHCDFLILG GGPAGLTAAI YAARAKLHTV VVDEGLIGGQ VATTFQVANY PGTNGVVRGI DLMENMKKQA LDFGAYIDDL KEISDVNLEG KEKLVTAKDT DYYAKAVLIA TGATPRRLPA EGEKEFRGRG VHYCATCDGA MYFDANILVV GGGESAAEEA VFLTRYAKHV TIINRHDYLK ASKTAQDEVF RNPNISVVWN SEVRKINGDS FVKSVTIENL KTGKIEEIET DGLFVYIGTQ PKTELFAGKV GMNEEGYILT NEDMATNIPG VFAAGDVRAK KVRQIATAVG DGAVAGIMAE RYINGKFY
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
PF00085: 4-106 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
PF07992: 123-411 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
Sequence: MNDAIVKST MENFDKDVLK SDIPVAVLFY TESCPVCDAF MPIFERTAQK YGKYMKFVKI YRQQNRQLVE DLKIKSSPTV LFYKEGNEVC TRLNGYISNA EFVEAIERVI GDVCKGEKRE KVHCDFLILG GGPAGLTAAI YAARAKLHTV VVDEGLIGGQ VATTFQVANY PGTNGVVRGI DLMENMKKQA LDFGAYIDDL KEISDVNLEG KEKLVTAKDT DYYAKAVLIA TGATPRRLPA EGEKEFRGRG VHYCATCDGA MYFDANILVV GGGESAAEEA VFLTRYAKHV TIINRHDYLK ASKTAQDEVF RNPNISVVWN SEVRKINGDS FVKSVTIENL KTGKIEEIET DGLFVYIGTQ PKTELFAGKV GMNEEGYILT NEDMATNIPG VFAAGDVRAK KVRQIATAVG DGAVAGIMAE RYINGKFY HMM: 3-54 AIVKST MENFDKDVLK SDIPVAVLFY TESCPVCDAF MPIFERTAQK YGKYMK ALI: 120-172 VHCDFLILG GGPAGLTAAI YAARAKLHTV VVDEGLIGGQ VATTFQVANY PGTN ENV: 118-181 E KVHCDFLILG GGPAGLTAAI YAARAKLHTV VVDEGLIGGQ VATTFQVANY PGTNGVVRGI DLM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
Sequence: MNDAIVKST MENFDKDVLK SDIPVAVLFY TESCPVCDAF MPIFERTAQK YGKYMKFVKI YRQQNRQLVE DLKIKSSPTV LFYKEGNEVC TRLNGYISNA EFVEAIERVI GDVCKGEKRE KVHCDFLILG GGPAGLTAAI YAARAKLHTV VVDEGLIGGQ VATTFQVANY PGTNGVVRGI DLMENMKKQA LDFGAYIDDL KEISDVNLEG KEKLVTAKDT DYYAKAVLIA TGATPRRLPA EGEKEFRGRG VHYCATCDGA MYFDANILVV GGGESAAEEA VFLTRYAKHV TIINRHDYLK ASKTAQDEVF RNPNISVVWN SEVRKINGDS FVKSVTIENL KTGKIEEIET DGLFVYIGTQ PKTELFAGKV GMNEEGYILT NEDMATNIPG VFAAGDVRAK KVRQIATAVG DGAVAGIMAE RYINGKFY HMM: 155-226 IGGQ VATTFQVANY PGTNGVVRGI DLMENMKKQA LDFGAYIDDL KEISDVNLEG KEKLVTAKDT DYYAKAVL ALI: 240-311 GEKEFRGRG VHYCATCDGA MYFDANILVV GGGESAAEEA VFLTRYAKHV TIINRHDYLK ASKTAQDEVF RNP ENV: 213-326 VTAKDT DYYAKAVLIA TGATPRRLPA EGEKEFRGRG VHYCATCDGA MYFDANILVV GGGESAAEEA VFLTRYAKHV TIINRHDYLK ASKTAQDEVF RNPNISVVWN SEVRKING Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
Sequence: MGKKVVVIG AGPGGIMAAG KAAERGHNVT LFEKNDRIGK KILISGKGRC NITNNTDIEG LIENIPGNGN FLYSAFYTFS NHDLIEFFEQ YGLKTKVERG GRVFPVSDDA KDVNNALLKF LNKAKVNLRL NSPVQEIKAK NNTVTGVVLK DGTEVPCDAV VLATGGASYP GTGSTGDGYV MAKKLGHTIV DLKPSLVPLL AEEEWVKELQ GLSLKNVSIT ILSKAGKKIY TDFGEMLFTH FGVSGPIILS ASRHILDYDY KNVKLVIDLK PALSEEKLDE RILRDFEKYS RKQYKNSLDD LLPKKMIPVI VKLSGIEPEK FVNQIKKEER RALVRLLKNL TLNINGSRPI KEAIVTAGGV STDEINPSTM ESKLVKGLYF AGEIIDVDGY TGGFNLTIAF STGYLAGVSC
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400
PF03486: 3-406 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
Sequence: MGKKVVVIG AGPGGIMAAG KAAERGHNVT LFEKNDRIGK KILISGKGRC NITNNTDIEG LIENIPGNGN FLYSAFYTFS NHDLIEFFEQ YGLKTKVERG GRVFPVSDDA KDVNNALLKF LNKAKVNLRL NSPVQEIKAK NNTVTGVVLK DGTEVPCDAV VLATGGASYP GTGSTGDGYV MAKKLGHTIV DLKPSLVPLL AEEEWVKELQ GLSLKNVSIT ILSKAGKKIY TDFGEMLFTH FGVSGPIILS ASRHILDYDY KNVKLVIDLK PALSEEKLDE RILRDFEKYS RKQYKNSLDD LLPKKMIPVI VKLSGIEPEK FVNQIKKEER RALVRLLKNL TLNINGSRPI KEAIVTAGGV STDEINPSTM ESKLVKGLYF AGEIIDVDGY TGGFNLTIAF STGYLAGVSC HMM: 178-209 V MAKKLGHTIV DLKPSLVPLL AEEEWVKELQ G ALI: 2-33 KKVVVIG AGPGGIMAAG KAAERGHNVT LFEKN ENV: 1-40 GKKVVVIG AGPGGIMAAG KAAERGHNVT LFEKNDRIGK KI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400
Sequence: MGKKVVVIG AGPGGIMAAG KAAERGHNVT LFEKNDRIGK KILISGKGRC NITNNTDIEG LIENIPGNGN FLYSAFYTFS NHDLIEFFEQ YGLKTKVERG GRVFPVSDDA KDVNNALLKF LNKAKVNLRL NSPVQEIKAK NNTVTGVVLK DGTEVPCDAV VLATGGASYP GTGSTGDGYV MAKKLGHTIV DLKPSLVPLL AEEEWVKELQ GLSLKNVSIT ILSKAGKKIY TDFGEMLFTH FGVSGPIILS ASRHILDYDY KNVKLVIDLK PALSEEKLDE RILRDFEKYS RKQYKNSLDD LLPKKMIPVI VKLSGIEPEK FVNQIKKEER RALVRLLKNL TLNINGSRPI KEAIVTAGGV STDEINPSTM ESKLVKGLYF AGEIIDVDGY TGGFNLTIAF STGYLAGVSC HMM: 317-344 EK FVNQIKKEER RALVRLLKNL TLNING ALI: 137-164 AK NNTVTGVVLK DGTEVPCDAV VLATGG ENV: 113-169 NALLKF LNKAKVNLRL NSPVQEIKAK NNTVTGVVLK DGTEVPCDAV VLATGGASYP G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400
Sequence: MSIEQQKIF AKPPQSYWMA STPKANYPTL EEDIKVDVAI IGGGITGIAT SYMLGKAGVK VAVIEADRIL QGTTGHTTAK ITSQHDLIYS KIYSQMGREL AQQYADANES AIRMIEKIAT ENGIECDFVP QSAYVYTMQD KYIDKIKDEA VIAESLGIKA TYLEEIPLPF PIKAAVRFDN QAQFHPRKFL LRLAEEIVKS GNQIFEQSRI VDIEDDNNYV LITNQGKKVT AEKLIIASHY PCYNKAGLYF TRLYPERSYV VAIKAKESYP GGMYINMEEP KRSLRSQRSD DGELILVGGE SHKTGQGEDT IKHYEALIDY ATKTFTVEDI PYRWSTQDCM TLDGLPYVGH FTSNTPNMYI ATGYGKWGMT NSIASAMILR DLIIEGKSPW QDVYNPSRKT VLASAKNFIV ENLNVAEKLI EGKILPMADN TDIKAGEGKI INVNGQRLGA YRDQQGTLHV VDTTCTHMGC ELYWNSAEKS WDCPCHGSRF TYEGDIIEGP AVTPLNVHRD VNTIEKLFKD NLRL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
PF01266: 35-380 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
PF00355: 424-505 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MSIEQQKIF AKPPQSYWMA STPKANYPTL EEDIKVDVAI IGGGITGIAT SYMLGKAGVK VAVIEADRIL QGTTGHTTAK ITSQHDLIYS KIYSQMGREL AQQYADANES AIRMIEKIAT ENGIECDFVP QSAYVYTMQD KYIDKIKDEA VIAESLGIKA TYLEEIPLPF PIKAAVRFDN QAQFHPRKFL LRLAEEIVKS GNQIFEQSRI VDIEDDNNYV LITNQGKKVT AEKLIIASHY PCYNKAGLYF TRLYPERSYV VAIKAKESYP GGMYINMEEP KRSLRSQRSD DGELILVGGE SHKTGQGEDT IKHYEALIDY ATKTFTVEDI PYRWSTQDCM TLDGLPYVGH FTSNTPNMYI ATGYGKWGMT NSIASAMILR DLIIEGKSPW QDVYNPSRKT VLASAKNFIV ENLNVAEKLI EGKILPMADN TDIKAGEGKI INVNGQRLGA YRDQQGTLHV VDTTCTHMGC ELYWNSAEKS WDCPCHGSRF TYEGDIIEGP AVTPLNVHRD VNTIEKLFKD NLRL HMM: 4-202 QQKIF AKPPQSYWMA STPKANYPTL EEDIKVDVAI IGGGITGIAT SYMLGKAGVK VAVIEADRIL QGTTGHTTAK ITSQHDLIYS KIYSQMGREL AQQYADANES AIRMIEKIAT ENGIECDFVP QSAYVYTMQD KYIDKIKDEA VIAESLGIKA TYLEEIPLPF PIKAAVRFDN QAQFHPRKFL LRLAEEIVKS GNQI ALI: 34-60 VDVAI IGGGITGIAT SYMLGKAGVK VA ENV: 25-121 YPTL EEDIKVDVAI IGGGITGIAT SYMLGKAGVK VAVIEADRIL QGTTGHTTAK ITSQHDLIYS KIYSQMGREL AQQYADANES AIRMIEKIAT ENG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MSIEQQKIF AKPPQSYWMA STPKANYPTL EEDIKVDVAI IGGGITGIAT SYMLGKAGVK VAVIEADRIL QGTTGHTTAK ITSQHDLIYS KIYSQMGREL AQQYADANES AIRMIEKIAT ENGIECDFVP QSAYVYTMQD KYIDKIKDEA VIAESLGIKA TYLEEIPLPF PIKAAVRFDN QAQFHPRKFL LRLAEEIVKS GNQIFEQSRI VDIEDDNNYV LITNQGKKVT AEKLIIASHY PCYNKAGLYF TRLYPERSYV VAIKAKESYP GGMYINMEEP KRSLRSQRSD DGELILVGGE SHKTGQGEDT IKHYEALIDY ATKTFTVEDI PYRWSTQDCM TLDGLPYVGH FTSNTPNMYI ATGYGKWGMT NSIASAMILR DLIIEGKSPW QDVYNPSRKT VLASAKNFIV ENLNVAEKLI EGKILPMADN TDIKAGEGKI INVNGQRLGA YRDQQGTLHV VDTTCTHMGC ELYWNSAEKS WDCPCHGSRF TYEGDIIEGP AVTPLNVHRD VNTIEKLFKD NLRL HMM: 366-427 GMT NSIASAMILR DLIIEGKSPW QDVYNPSRKT VLASAKNFIV ENLNVAEKLI EGKILPMAD ALI: 343-402 LPYVGH FTSNTPNMYI ATGYGKWGMT NSIASAMILR DLIIEGKSPW QDVYNPSRKT VLAS ENV: 328-432 I PYRWSTQDCM TLDGLPYVGH FTSNTPNMYI ATGYGKWGMT NSIASAMILR DLIIEGKSPW QDVYNPSRKT VLASAKNFIV ENLNVAEKLI EGKILPMADN TDIK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MDAWRGFNK GNWCQEIDVR DFIIRNYTPY EGDESFLVGP TDRTRKLWEK VSELLKKERE NGGVLDVDTH TISTITSHKP GYIDKELEVI VGLQTDEPLK RAIMPFGGIR MVIKGAEAYG HSVDPQVVEI FTKYRKTHNQ GVYDVYTPEM RKAKKAGIIT GLPDAYGRGR IIGDYRRVAL YGVDRLIAEK EKEMASLERD YIDYETVRDR EEISEQIKSL KQLKEMALSY GFDISCPAKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDYGIACCVS AMRIGKQMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACGIAGLSV VADSLSAIKY AKVKPIRNEN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
PF02901: 14-601 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF01228: 617-723 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MDAWRGFNK GNWCQEIDVR DFIIRNYTPY EGDESFLVGP TDRTRKLWEK VSELLKKERE NGGVLDVDTH TISTITSHKP GYIDKELEVI VGLQTDEPLK RAIMPFGGIR MVIKGAEAYG HSVDPQVVEI FTKYRKTHNQ GVYDVYTPEM RKAKKAGIIT GLPDAYGRGR IIGDYRRVAL YGVDRLIAEK EKEMASLERD YIDYETVRDR EEISEQIKSL KQLKEMALSY GFDISCPAKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDYGIACCVS AMRIGKQMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACGIAGLSV VADSLSAIKY AKVKPIRNEN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI HMM: 291-571 ELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDYGIACCVS AMRIGKQMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACGIAGLSV VADSLSAIKY AKVKPIRNEN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMF ALI: 236-503 AKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDYGIACCVS AMRIGKQMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDK ENV: 220-512 QLKEMALSY GFDISCPAKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDYGIACCVS AMRIGKQMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDAWRGFNK GNWCQEIDVR DFIIRNYTPY EGDESFLVGP TDRTRKLWEK VSELLKKERE NGGVLDVDTH TISTITSHKP GYIDKELEVI VGLQTDEPLK RAIMPFGGIR MVIKGAEAYG HSVDPQVVEI FTKYRKTHNQ GVYDVYTPEM RKAKKAGIIT GLPDAYGRGR IIGDYRRVAL YGVDRLIAEK EKEMASLERD YIDYETVRDR EEISEQIKSL KQLKEMALSY GFDISCPAKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDYGIACCVS AMRIGKQMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACGIAGLSV VADSLSAIKY AKVKPIRNEN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI HMM: 644-831 EYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI ALI: 551-739 PKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH G ENV: 542-741 VDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDAWRGFNK GNWCQEIDVR DFIIRNYTPY EGDESFLVGP TDRTRKLWEK VSELLKKERE NGGVLDVDTH TISTITSHKP GYIDKELEVI VGLQTDEPLK RAIMPFGGIR MVIKGAEAYG HSVDPQVVEI FTKYRKTHNQ GVYDVYTPEM RKAKKAGIIT GLPDAYGRGR IIGDYRRVAL YGVDRLIAEK EKEMASLERD YIDYETVRDR EEISEQIKSL KQLKEMALSY GFDISCPAKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDYGIACCVS AMRIGKQMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACGIAGLSV VADSLSAIKY AKVKPIRNEN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI HMM: 299-401 KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDY ALI: 236-335 AKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRT ENV: 231-367 DISCPAKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDAWRGFNK GNWCQEIDVR DFIIRNYTPY EGDESFLVGP TDRTRKLWEK VSELLKKERE NGGVLDVDTH TISTITSHKP GYIDKELEVI VGLQTDEPLK RAIMPFGGIR MVIKGAEAYG HSVDPQVVEI FTKYRKTHNQ GVYDVYTPEM RKAKKAGIIT GLPDAYGRGR IIGDYRRVAL YGVDRLIAEK EKEMASLERD YIDYETVRDR EEISEQIKSL KQLKEMALSY GFDISCPAKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDYGIACCVS AMRIGKQMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACGIAGLSV VADSLSAIKY AKVKPIRNEN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI HMM: 515-582 GLSV VADSLSAIKY AKVKPIRNEN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYR ALI: 427-494 KA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYE ENV: 415-512 QMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDAWRGFNK GNWCQEIDVR DFIIRNYTPY EGDESFLVGP TDRTRKLWEK VSELLKKERE NGGVLDVDTH TISTITSHKP GYIDKELEVI VGLQTDEPLK RAIMPFGGIR MVIKGAEAYG HSVDPQVVEI FTKYRKTHNQ GVYDVYTPEM RKAKKAGIIT GLPDAYGRGR IIGDYRRVAL YGVDRLIAEK EKEMASLERD YIDYETVRDR EEISEQIKSL KQLKEMALSY GFDISCPAKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDYGIACCVS AMRIGKQMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACGIAGLSV VADSLSAIKY AKVKPIRNEN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI HMM: 662-846 GRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI ALI: 551-737 PKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTI ENV: 537-740 EN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDAWRGFNK GNWCQEIDVR DFIIRNYTPY EGDESFLVGP TDRTRKLWEK VSELLKKERE NGGVLDVDTH TISTITSHKP GYIDKELEVI VGLQTDEPLK RAIMPFGGIR MVIKGAEAYG HSVDPQVVEI FTKYRKTHNQ GVYDVYTPEM RKAKKAGIIT GLPDAYGRGR IIGDYRRVAL YGVDRLIAEK EKEMASLERD YIDYETVRDR EEISEQIKSL KQLKEMALSY GFDISCPAKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDYGIACCVS AMRIGKQMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACGIAGLSV VADSLSAIKY AKVKPIRNEN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI HMM: 73-108 ITSHKP GYIDKELEVI VGLQTDEPLK RAIMPFGGIR ALI: 78-114 P GYIDKELEVI VGLQTDEPLK RAIMPFGGIR MVIKGA ENV: 54-198 KKERE NGGVLDVDTH TISTITSHKP GYIDKELEVI VGLQTDEPLK RAIMPFGGIR MVIKGAEAYG HSVDPQVVEI FTKYRKTHNQ GVYDVYTPEM RKAKKAGIIT GLPDAYGRGR IIGDYRRVAL YGVDRLIAEK EKEMASLERD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDAWRGFNK GNWCQEIDVR DFIIRNYTPY EGDESFLVGP TDRTRKLWEK VSELLKKERE NGGVLDVDTH TISTITSHKP GYIDKELEVI VGLQTDEPLK RAIMPFGGIR MVIKGAEAYG HSVDPQVVEI FTKYRKTHNQ GVYDVYTPEM RKAKKAGIIT GLPDAYGRGR IIGDYRRVAL YGVDRLIAEK EKEMASLERD YIDYETVRDR EEISEQIKSL KQLKEMALSY GFDISCPAKD AREAFQWLYF AYLAAVKEQN GAAMSIGRIS TFLDIYIERD LKEGKLTEEL AQELVDQLVI KLRIVRFLRT PEYEKLFSGD PTWVTESIGG MALDGRTLVT KSSFRFLHTL FNLGHAPEPN LTVLWSVNLP EGFKKYCAKV SIHSSSIQYE SDDIMRKHWG DDYGIACCVS AMRIGKQMQF FGARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACGIAGLSV VADSLSAIKY AKVKPIRNEN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI HMM: 633-817 AVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GKI ALI: 551-737 PKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTI ENV: 421-740 ARCNLAKA LLYAINGGKD EMTGEQIAPM FAPVETEYLD YEDVMKRFDM VLDWVARLYM NTLNIIHYMH DKYAYEALQM ALHDKDVFRT MACGIAGLSV VADSLSAIKY AKVKPIRNEN NLVVDYEVEG DYPKFGNNDE RVDEIAVQVV KMFMNKLRKQ RAYRSATPTL SILTITSNVV YGKKTGNTPD GRKAGEPLAP GANPMHGRDI NGALAVLNSI AKLPYEYAQD GISYTFSIIP KALGRDEETR INNLKSMLDG YFKQGGHHIN VNVFEKETLL DAMEHPEKYP QLTIRVSGYA VNFIKLTREQ QLDVINRTIH GK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MEIEYLRKI LESVRDGNIG IDEALTKLKN LPFEDLGFAK VDEHRNIRNG YPEVIYCQGK TVEQVKKIVE KLMEKNNNIM ATRADIKCFE AIREITDDAV YYEQARIVVV KKRDIPKVDK MIAVVTAGTA DIPVAEEAAV TCEIMGNSVE RVYDVGVAGI HRLFARLDVI RAANVLIVVA GMEGALASVV SGLVDKPVIA VPTSVGYGAN FGGLSALLTM LNSCAAGIGV VNIDNGFGAG FLASMINKL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240
PF00731: 120-245 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
Sequence: MEIEYLRKI LESVRDGNIG IDEALTKLKN LPFEDLGFAK VDEHRNIRNG YPEVIYCQGK TVEQVKKIVE KLMEKNNNIM ATRADIKCFE AIREITDDAV YYEQARIVVV KKRDIPKVDK MIAVVTAGTA DIPVAEEAAV TCEIMGNSVE RVYDVGVAGI HRLFARLDVI RAANVLIVVA GMEGALASVV SGLVDKPVIA VPTSVGYGAN FGGLSALLTM LNSCAAGIGV VNIDNGFGAG FLASMINKL HMM: 239-288 FLASMINKL ALI: 48-97 G YPEVIYCQGK TVEQVKKIVE KLMEKNNNIM ATRADIKCFE AIREITDDA ENV: 39-127 VDEHRNIRNG YPEVIYCQGK TVEQVKKIVE KLMEKNNNIM ATRADIKCFE AIREITDDAV YYEQARIVVV KKRDIPKVDK MIAVVTAGT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240
Sequence: MLDLKRIRT NPEEIKKALT NRGEDFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKSGQ NADELLAEMK KISDDIKGID AKVSEIDEKM QYIMLRIPNI PHPSVPEGKS DEENVEIRKW GEPRKFDFEF KAHWDIGTDL GLLDFERGGK VAGSRFTFYK GLGARLERAV INYFLDTHVE KHGYTEILPP YMVNRVSMTG TGQLPKFEED AFKVDNGFFL IPTAEVPVTN MFRDEILKAE DLPYKFAAYS ACFRSEAGSA GRDTRGLVRQ HQFNKVELVK FAKPEESYDE LEKLTHDAEE ILQILNIPYR VVRICKGDLG FTAALKYDIE VWMPSYGRYV EISSCSNFED FQARRANIKF RRDPKAKPEF VHTLNGSGLA VGRTVAAILE NYQNEDGSVN VPEALKKYIG KDVIR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
PF02403: 0-110 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
PF00587: 223-401 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
Sequence: MLDLKRIRT NPEEIKKALT NRGEDFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKSGQ NADELLAEMK KISDDIKGID AKVSEIDEKM QYIMLRIPNI PHPSVPEGKS DEENVEIRKW GEPRKFDFEF KAHWDIGTDL GLLDFERGGK VAGSRFTFYK GLGARLERAV INYFLDTHVE KHGYTEILPP YMVNRVSMTG TGQLPKFEED AFKVDNGFFL IPTAEVPVTN MFRDEILKAE DLPYKFAAYS ACFRSEAGSA GRDTRGLVRQ HQFNKVELVK FAKPEESYDE LEKLTHDAEE ILQILNIPYR VVRICKGDLG FTAALKYDIE VWMPSYGRYV EISSCSNFED FQARRANIKF RRDPKAKPEF VHTLNGSGLA VGRTVAAILE NYQNEDGSVN VPEALKKYIG KDVIR HMM: 53-94 RNKDSG EIAKLKKSGQ NADELLAEMK KISDDIKGID AKVSEI ALI: 23-66 DFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKS ENV: 15-85 KALT NRGEDFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKSGQ NADELLAEMK KISDDIK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
Sequence: MLDLKRIRT NPEEIKKALT NRGEDFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKSGQ NADELLAEMK KISDDIKGID AKVSEIDEKM QYIMLRIPNI PHPSVPEGKS DEENVEIRKW GEPRKFDFEF KAHWDIGTDL GLLDFERGGK VAGSRFTFYK GLGARLERAV INYFLDTHVE KHGYTEILPP YMVNRVSMTG TGQLPKFEED AFKVDNGFFL IPTAEVPVTN MFRDEILKAE DLPYKFAAYS ACFRSEAGSA GRDTRGLVRQ HQFNKVELVK FAKPEESYDE LEKLTHDAEE ILQILNIPYR VVRICKGDLG FTAALKYDIE VWMPSYGRYV EISSCSNFED FQARRANIKF RRDPKAKPEF VHTLNGSGLA VGRTVAAILE NYQNEDGSVN VPEALKKYIG KDVIR HMM: 8-78 T NPEEIKKALT NRGEDFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKSGQ NADELLAEMK ALI: 289-359 FAKPEESYDE LEKLTHDAEE ILQILNIPYR VVRICKGDLG FTAALKYDIE VWMPSYGRYV EISSCSNFED F ENV: 283-381 KVELVK FAKPEESYDE LEKLTHDAEE ILQILNIPYR VVRICKGDLG FTAALKYDIE VWMPSYGRYV EISSCSNFED FQARRANIKF RRDPKAKPEF VHT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
Sequence: MKKYVCVVC GYIYDPAEGD PDNGVNPGTS FEDIPDDWVC PLCGVGKDQF EPSEE
10 20 30 40 50
PF00301: 2-49 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MKKYVCVVC GYIYDPAEGD PDNGVNPGTS FEDIPDDWVC PLCGVGKDQF EPSEE HMM: 424-469 ALI: 2-47 KYVCVVC GYIYDPAEGD PDNGVNPGTS FEDIPDDWVC PLCGVGKDQ ENV: 1-54 KKYVCVVC GYIYDPAEGD PDNGVNPGTS FEDIPDDWVC PLCGVGKDQF EPSEE Position: 10 20 30 40 50
Sequence: MKKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGNITSVK LTDTEKIIET SDTIYKPKSV IIATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVYI GTMPKTELFK DFIDLTELGH IKTNENLETN IKGVFAAGDV REKEIRQLTT AVNDGSIASL MAEKYIRNS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
PF07992: 7-294 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌
Sequence: MKKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGNITSVK LTDTEKIIET SDTIYKPKSV IIATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVYI GTMPKTELFK DFIDLTELGH IKTNENLETN IKGVFAAGDV REKEIRQLTT AVNDGSIASL MAEKYIRNS HMM: 2-44 KEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIR ALI: 3-42 EKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQ ENV: 1-64 KKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MKKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGNITSVK LTDTEKIIET SDTIYKPKSV IIATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVYI GTMPKTELFK DFIDLTELGH IKTNENLETN IKGVFAAGDV REKEIRQLTT AVNDGSIASL MAEKYIRNS HMM: 154-225 GNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGE ALI: 122-193 PEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKH ENV: 111-237 ATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MKKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGNITSVK LTDTEKIIET SDTIYKPKSV IIATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVYI GTMPKTELFK DFIDLTELGH IKTNENLETN IKGVFAAGDV REKEIRQLTT AVNDGSIASL MAEKYIRNS HMM: 2-43 KEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQI ALI: 4-42 KILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQ ENV: 3-83 EKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MKKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGNITSVK LTDTEKIIET SDTIYKPKSV IIATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVYI GTMPKTELFK DFIDLTELGH IKTNENLETN IKGVFAAGDV REKEIRQLTT AVNDGSIASL MAEKYIRNS HMM: 152-226 GGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEK ALI: 122-195 PEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNN ENV: 112-214 TGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MNNYRNVFK PIKIGNILVK NRIEVSPAEP FLASKDGYVT QEFIEWTRAM AKGGAGIVTI GDSPVNAEYA KSSPYVIDMS KDTIVNGLYT LTEVIHRYGA KASLELNLRA DYTPTDMTKE KIKQVINDFA DAAFRCKQAG MDMVMIHGGH GHLVAQFFSP FYNKRTDEYS TSNMENRTRF ARELLDAVRE KIGNDMAIEY RISADELNEH GVRIGEALEF AKIIQEKIDL IHVSVGDLYK PEAIPFMIQP TYIPQGINVN YAERFKKELN IPVTTVGSLD IDIAEQVIIE EKADMVAMIR AFIADSDFVN KAKYGEERTI RPCIRCTTCV GQSPHAYCIP IRCAVNPMNG REREFMNMPF QETKKKVVVI GGGPAGMEAA RDAAKRGHKV IIMEKSDELG GFLKVASASS LKNDMRRYLQ WAVNMTMESQ NIEVRLNTEA TVENVKAENP DAIVIAVGSK VFIPDIPGVE KKNVIWAGDI AQRKMDTGNK VIVVGAGLTG SEAALLLARK GKKVTLVDMR PLKDLDANSP AIATSTLRSM LQSEDVKTIT GIKLKEISDE DAVFVDERQQ EHVICCDTLV LALGVTPRTE VVNKFKELVK EVYVIGDCNN KSGNLIKATT EGFFAAMSI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620
PF00724: 110-315 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF07992: 363-608 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MNNYRNVFK PIKIGNILVK NRIEVSPAEP FLASKDGYVT QEFIEWTRAM AKGGAGIVTI GDSPVNAEYA KSSPYVIDMS KDTIVNGLYT LTEVIHRYGA KASLELNLRA DYTPTDMTKE KIKQVINDFA DAAFRCKQAG MDMVMIHGGH GHLVAQFFSP FYNKRTDEYS TSNMENRTRF ARELLDAVRE KIGNDMAIEY RISADELNEH GVRIGEALEF AKIIQEKIDL IHVSVGDLYK PEAIPFMIQP TYIPQGINVN YAERFKKELN IPVTTVGSLD IDIAEQVIIE EKADMVAMIR AFIADSDFVN KAKYGEERTI RPCIRCTTCV GQSPHAYCIP IRCAVNPMNG REREFMNMPF QETKKKVVVI GGGPAGMEAA RDAAKRGHKV IIMEKSDELG GFLKVASASS LKNDMRRYLQ WAVNMTMESQ NIEVRLNTEA TVENVKAENP DAIVIAVGSK VFIPDIPGVE KKNVIWAGDI AQRKMDTGNK VIVVGAGLTG SEAALLLARK GKKVTLVDMR PLKDLDANSP AIATSTLRSM LQSEDVKTIT GIKLKEISDE DAVFVDERQQ EHVICCDTLV LALGVTPRTE VVNKFKELVK EVYVIGDCNN KSGNLIKATT EGFFAAMSI HMM: 175-245 RTRF ARELLDAVRE KIGNDMAIEY RISADELNEH GVRIGEALEF AKIIQEKIDL IHVSVGDLYK PEAIPFM ALI: 360-431 ETKKKVVVI GGGPAGMEAA RDAAKRGHKV IIMEKSDELG GFLKVASASS LKNDMRRYLQ WAVNMTMESQ NIE ENV: 354-454 MNMPF QETKKKVVVI GGGPAGMEAA RDAAKRGHKV IIMEKSDELG GFLKVASASS LKNDMRRYLQ WAVNMTMESQ NIEVRLNTEA TVENVKAENP DAIVIA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620
Sequence: MNNYRNVFK PIKIGNILVK NRIEVSPAEP FLASKDGYVT QEFIEWTRAM AKGGAGIVTI GDSPVNAEYA KSSPYVIDMS KDTIVNGLYT LTEVIHRYGA KASLELNLRA DYTPTDMTKE KIKQVINDFA DAAFRCKQAG MDMVMIHGGH GHLVAQFFSP FYNKRTDEYS TSNMENRTRF ARELLDAVRE KIGNDMAIEY RISADELNEH GVRIGEALEF AKIIQEKIDL IHVSVGDLYK PEAIPFMIQP TYIPQGINVN YAERFKKELN IPVTTVGSLD IDIAEQVIIE EKADMVAMIR AFIADSDFVN KAKYGEERTI RPCIRCTTCV GQSPHAYCIP IRCAVNPMNG REREFMNMPF QETKKKVVVI GGGPAGMEAA RDAAKRGHKV IIMEKSDELG GFLKVASASS LKNDMRRYLQ WAVNMTMESQ NIEVRLNTEA TVENVKAENP DAIVIAVGSK VFIPDIPGVE KKNVIWAGDI AQRKMDTGNK VIVVGAGLTG SEAALLLARK GKKVTLVDMR PLKDLDANSP AIATSTLRSM LQSEDVKTIT GIKLKEISDE DAVFVDERQQ EHVICCDTLV LALGVTPRTE VVNKFKELVK EVYVIGDCNN KSGNLIKATT EGFFAAMSI HMM: 149-211 GHLVAQFFSP FYNKRTDEYS TSNMENRTRF ARELLDAVRE KIGNDMAIEY RISADELNEH GVR ALI: 460-520 FIPDIPGVE KKNVIWAGDI AQRKMDTGNK VIVVGAGLTG SEAALLLARK GKKVTLVDMR PL ENV: 420-549 AVNMTMESQ NIEVRLNTEA TVENVKAENP DAIVIAVGSK VFIPDIPGVE KKNVIWAGDI AQRKMDTGNK VIVVGAGLTG SEAALLLARK GKKVTLVDMR PLKDLDANSP AIATSTLRSM LQSEDVKTIT G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620
Sequence: MSYDVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKRKCPIDGK KIKACINCSV CNIMNGYGGA GSLSDGKYNI TNNFGGDLHK YVGAEEAIDL MNYVDSVLCS MGGEDAKLYS TENSKLKAKA LQYDLHLLDA KVRHLGTDRN LIIMANIFDF LKDKMDIIFD TEVLNIYKGD ELFNIETSNK TFSSKELILA TGRSGSKWIS DMCAKVGIKT KSNRVDIGVR VELPAEVFSH ITDAVYESKI VYKTKKYNDM VRTFCMNPYG EVVNENTNGI ITVNGHSYAN PELRTENTNF ALLVTNNFTE PFEDSNEYGA SIARLSNMLG GGVLVQRFGD LVNGRRTNEH RMEKSFTTPT LKATPGDLGL VIPKRQLDDI IEMIYALNNI APGTANEDTL LYGVEVKFYN SKVEVDKNLE TKIKGLYILG DGSGVTHSLS QAAASGVYIA RILAEKYR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450
Sequence: MSYDVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKRKCPIDGK KIKACINCSV CNIMNGYGGA GSLSDGKYNI TNNFGGDLHK YVGAEEAIDL MNYVDSVLCS MGGEDAKLYS TENSKLKAKA LQYDLHLLDA KVRHLGTDRN LIIMANIFDF LKDKMDIIFD TEVLNIYKGD ELFNIETSNK TFSSKELILA TGRSGSKWIS DMCAKVGIKT KSNRVDIGVR VELPAEVFSH ITDAVYESKI VYKTKKYNDM VRTFCMNPYG EVVNENTNGI ITVNGHSYAN PELRTENTNF ALLVTNNFTE PFEDSNEYGA SIARLSNMLG GGVLVQRFGD LVNGRRTNEH RMEKSFTTPT LKATPGDLGL VIPKRQLDDI IEMIYALNNI APGTANEDTL LYGVEVKFYN SKVEVDKNLE TKIKGLYILG DGSGVTHSLS QAAASGVYIA RILAEKYR HMM: 6-39 IVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL E ALI: 3-36 DVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGH ENV: 1-41 SYDVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450
Sequence: MSYDVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKRKCPIDGK KIKACINCSV CNIMNGYGGA GSLSDGKYNI TNNFGGDLHK YVGAEEAIDL MNYVDSVLCS MGGEDAKLYS TENSKLKAKA LQYDLHLLDA KVRHLGTDRN LIIMANIFDF LKDKMDIIFD TEVLNIYKGD ELFNIETSNK TFSSKELILA TGRSGSKWIS DMCAKVGIKT KSNRVDIGVR VELPAEVFSH ITDAVYESKI VYKTKKYNDM VRTFCMNPYG EVVNENTNGI ITVNGHSYAN PELRTENTNF ALLVTNNFTE PFEDSNEYGA SIARLSNMLG GGVLVQRFGD LVNGRRTNEH RMEKSFTTPT LKATPGDLGL VIPKRQLDDI IEMIYALNNI APGTANEDTL LYGVEVKFYN SKVEVDKNLE TKIKGLYILG DGSGVTHSLS QAAASGVYIA RILAEKYR HMM: 5-41 IIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKR ALI: 3-39 DVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL E ENV: 1-43 SYDVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKRKC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450
Sequence: MDNPNLLSE EANRCLLCKN PRCKANCPIN TPIPEIISLY KEGKIMEAGE ILFNNNPLSV ICSLVCIHED QCKGNCVRGI KSEPIKFHEI EEEISEKYLK EAKLKNVQKD KDRIAIVGGG PAGITVAFVL ANKGYNVTIF EAHDKIGGVL RYGIPEYRLT KKLVDKLEER LIEVGVKIRP NTVIGPVISL DRLLEDSYKA VFIGTGVWNP KTLDVKGETL GNVHFAIDYL KSPESYRLGK KVAVIGAGNV AMDAARTAKR NGAEVTILYR KSFNEMPASK QEIRETKEDG VEFKLFRAPI EITEEGIKVA FTENVTDAEG KIRTKIIEGK EEFFECDSVV VAVSQAPKDN IVSNTTGLDT KWGLIVTDEK GNTTKKGTFA CGDVVTGAKT VVEAAAQAKV VAETIDEYCK NN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
PF14691: 7-98 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF13450: 114-149 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
PF07992: 194-397 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MDNPNLLSE EANRCLLCKN PRCKANCPIN TPIPEIISLY KEGKIMEAGE ILFNNNPLSV ICSLVCIHED QCKGNCVRGI KSEPIKFHEI EEEISEKYLK EAKLKNVQKD KDRIAIVGGG PAGITVAFVL ANKGYNVTIF EAHDKIGGVL RYGIPEYRLT KKLVDKLEER LIEVGVKIRP NTVIGPVISL DRLLEDSYKA VFIGTGVWNP KTLDVKGETL GNVHFAIDYL KSPESYRLGK KVAVIGAGNV AMDAARTAKR NGAEVTILYR KSFNEMPASK QEIRETKEDG VEFKLFRAPI EITEEGIKVA FTENVTDAEG KIRTKIIEGK EEFFECDSVV VAVSQAPKDN IVSNTTGLDT KWGLIVTDEK GNTTKKGTFA CGDVVTGAKT VVEAAAQAKV VAETIDEYCK NN HMM: 7-45 SE EANRCLLCKN PRCKANCPIN TPIPEIISLY KEGKIME ALI: 112-148 IAIVGGG PAGITVAFVL ANKGYNVTIF EAHDKIGGVL ENV: 104-156 NVQKD KDRIAIVGGG PAGITVAFVL ANKGYNVTIF EAHDKIGGVL RYGIPEYR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MDNPNLLSE EANRCLLCKN PRCKANCPIN TPIPEIISLY KEGKIMEAGE ILFNNNPLSV ICSLVCIHED QCKGNCVRGI KSEPIKFHEI EEEISEKYLK EAKLKNVQKD KDRIAIVGGG PAGITVAFVL ANKGYNVTIF EAHDKIGGVL RYGIPEYRLT KKLVDKLEER LIEVGVKIRP NTVIGPVISL DRLLEDSYKA VFIGTGVWNP KTLDVKGETL GNVHFAIDYL KSPESYRLGK KVAVIGAGNV AMDAARTAKR NGAEVTILYR KSFNEMPASK QEIRETKEDG VEFKLFRAPI EITEEGIKVA FTENVTDAEG KIRTKIIEGK EEFFECDSVV VAVSQAPKDN IVSNTTGLDT KWGLIVTDEK GNTTKKGTFA CGDVVTGAKT VVEAAAQAKV VAETIDEYCK NN HMM: 170-210 IEVGVKIRP NTVIGPVISL DRLLEDSYKA VFIGTGVWNP KT ALI: 231-270 PESYRLGK KVAVIGAGNV AMDAARTAKR NGAEVTILYR KS ENV: 208-283 P KTLDVKGETL GNVHFAIDYL KSPESYRLGK KVAVIGAGNV AMDAARTAKR NGAEVTILYR KSFNEMPASK QEIRE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MNRNLVVAL AGNPNCGKTS LFNELTGSKQ HVGNWPGVTV EKKEGKLKFE GREITIVDLP GTYSLGAYSE DEVVARDFIL KDKPDVVINV VDACNLERNL YLTTQILETG AKVVLALNMM DEANTRNIDI NIEKLQKSIG IPVVPTVATK KQGIKELVKN AIKLGDSESE ELYTIDYGSD IQKEVDGIKA AIDEASVTLE YPKAWVSLKL LENDDYIRKY IDNSIKDDEV KHKVSEGIEN LTSIIGYEPD AFIVDKRYEL ISKFVKNSVK KNEVQEESTS DKIDKVLTNK FLGIPIFAII MFAVYQVSIN FGNGTLSDLI NDSLGQLGTN IAFTLDGFGV PKIIGAFVRD GVFAGVGSVL GFFPMILIMF FLISLLEDSG YMARAAYVMD RLMSAVGLHG KTAVSLIVGS GCNVAGIMSA RTLESKKDRM IAILITPFIS CPARLTVYGV FVGAFFAKQK LGIFSLGGII IFLLYALGIF VAICAGKFFS SKVFEGETSY FVMELPPYRL PTLKGILIHM WEKSGHFLKK AGTIILGVCI IVWILADLPA GVEYGSKDSL LGIIGTFIAP IFKPAGFGSW QAGVALITGF AAKEAVVGTL GTIYGVNEGT QLFHAIHNTF TPLSAISFMI MTLLYVPCVA TIGAVKSETN SNKWTVAVII YTCVIGWVLA TIFYQVGRLL GYV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF02421: 5-159 ◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
PF17910: 175-269 ◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
PF07670: 526-650 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
PF07664: 469-522 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MNRNLVVAL AGNPNCGKTS LFNELTGSKQ HVGNWPGVTV EKKEGKLKFE GREITIVDLP GTYSLGAYSE DEVVARDFIL KDKPDVVINV VDACNLERNL YLTTQILETG AKVVLALNMM DEANTRNIDI NIEKLQKSIG IPVVPTVATK KQGIKELVKN AIKLGDSESE ELYTIDYGSD IQKEVDGIKA AIDEASVTLE YPKAWVSLKL LENDDYIRKY IDNSIKDDEV KHKVSEGIEN LTSIIGYEPD AFIVDKRYEL ISKFVKNSVK KNEVQEESTS DKIDKVLTNK FLGIPIFAII MFAVYQVSIN FGNGTLSDLI NDSLGQLGTN IAFTLDGFGV PKIIGAFVRD GVFAGVGSVL GFFPMILIMF FLISLLEDSG YMARAAYVMD RLMSAVGLHG KTAVSLIVGS GCNVAGIMSA RTLESKKDRM IAILITPFIS CPARLTVYGV FVGAFFAKQK LGIFSLGGII IFLLYALGIF VAICAGKFFS SKVFEGETSY FVMELPPYRL PTLKGILIHM WEKSGHFLKK AGTIILGVCI IVWILADLPA GVEYGSKDSL LGIIGTFIAP IFKPAGFGSW QAGVALITGF AAKEAVVGTL GTIYGVNEGT QLFHAIHNTF TPLSAISFMI MTLLYVPCVA TIGAVKSETN SNKWTVAVII YTCVIGWVLA TIFYQVGRLL GYV HMM: 60-105 TYSLGAYSE DEVVARDFIL KDKPDVVINV VDACNLERNL YLTTQIL ALI: 195-239 VTLE YPKAWVSLKL LENDDYIRKY IDNSIKDDEV KHKVSEGIEN L ENV: 179-268 IQKEVDGIKA AIDEASVTLE YPKAWVSLKL LENDDYIRKY IDNSIKDDEV KHKVSEGIEN LTSIIGYEPD AFIVDKRYEL ISKFVKNSVK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MENHDLVIV GGGISGLQAA ISAKKSGVQD IVLIEAEDSL GGILNQCIYT GFGMEDFKEE LTGTEYVQRF IDEFLELNIE YKLNTTVIKI SKNKVITAVS PNEGIIEIKA CSIIFAAGAV EKPQKSIRVL TKDLSGIYSA LTVGRFINIH GYMPGKSIVI LGANKIGNAL ANRIFIEGGK VKAVIDSEVG FDERNEIIEF LAEINIPFLY NYNIVKIKGS ERIEGIYISD ENGEKFISCD TLILALKLNP NDKILREANI KILNKERNEI NTNVPGVFIV GNALYIHESN EGSPLENRKA GEMSAEYIRA TL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310
PF07992: 3-283 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌
Sequence: MENHDLVIV GGGISGLQAA ISAKKSGVQD IVLIEAEDSL GGILNQCIYT GFGMEDFKEE LTGTEYVQRF IDEFLELNIE YKLNTTVIKI SKNKVITAVS PNEGIIEIKA CSIIFAAGAV EKPQKSIRVL TKDLSGIYSA LTVGRFINIH GYMPGKSIVI LGANKIGNAL ANRIFIEGGK VKAVIDSEVG FDERNEIIEF LAEINIPFLY NYNIVKIKGS ERIEGIYISD ENGEKFISCD TLILALKLNP NDKILREANI KILNKERNEI NTNVPGVFIV GNALYIHESN EGSPLENRKA GEMSAEYIRA TL HMM: 5-53 LVIV GGGISGLQAA ISAKKSGVQD IVLIEAEDSL GGILNQCIYT GFGME ALI: 4-51 DLVIV GGGISGLQAA ISAKKSGVQD IVLIEAEDSL GGILNQCIYT GFG ENV: 1-58 ENHDLVIV GGGISGLQAA ISAKKSGVQD IVLIEAEDSL GGILNQCIYT GFGMEDFKEE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310
Sequence: MKDNKINIL FLSWRDIKCP KSGGAEVFTH EMLKRLDFNK YDITHFSPTF EGAKEKEIID NVTYIRRGNI LSVISEAKKY YKTNKDEIDF VVDQCNTHKF FTPLWVPKKK RIFFIHQLTR EIWHINARFP ISTLGYLFET PTLRLYKNDY TITVSDSTKK DLIDIGFDRD KVTIFPEGIN FKPWDKDSLL KEKDNIFGYI GRFVNYKGID AAVKAYCILK KDYPNSKLWI IGKKKDDYIE KVLLPILKEN NITYGNRGQN RDITFWGFVS EKEKLSLMSK MKALLFPSIR EGFGLTVIEA GAVGTPTVVY NSKGLVDAVD KGKAGYLCEE NTPENLYYFM KNILENENEY GLKRKNAHDF SLKFNWDSTS KYFDDFINKL NEKSLKK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF13439: 21-179 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
PF00534: 182-349 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MKDNKINIL FLSWRDIKCP KSGGAEVFTH EMLKRLDFNK YDITHFSPTF EGAKEKEIID NVTYIRRGNI LSVISEAKKY YKTNKDEIDF VVDQCNTHKF FTPLWVPKKK RIFFIHQLTR EIWHINARFP ISTLGYLFET PTLRLYKNDY TITVSDSTKK DLIDIGFDRD KVTIFPEGIN FKPWDKDSLL KEKDNIFGYI GRFVNYKGID AAVKAYCILK KDYPNSKLWI IGKKKDDYIE KVLLPILKEN NITYGNRGQN RDITFWGFVS EKEKLSLMSK MKALLFPSIR EGFGLTVIEA GAVGTPTVVY NSKGLVDAVD KGKAGYLCEE NTPENLYYFM KNILENENEY GLKRKNAHDF SLKFNWDSTS KYFDDFINKL NEKSLKK HMM: 62-109 YIRRGNI LSVISEAKKY YKTNKDEIDF VVDQCNTHKF FTPLWVPKKK R ALI: 176-222 GIN FKPWDKDSLL KEKDNIFGYI GRFVNYKGID AAVKAYCILK KDYP ENV: 160-243 LIDIGFDRD KVTIFPEGIN FKPWDKDSLL KEKDNIFGYI GRFVNYKGID AAVKAYCILK KDYPNSKLWI IGKKKDDYIE KVLLP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
PF02901: 16-601 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF01228: 616-724 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 290-420 QEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FG ALI: 235-366 PAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNN ENV: 210-381 EVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 481-569 LNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV N ALI: 412-501 IGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALH ENV: 400-512 DYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 644-831 RSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM ALI: 551-740 PKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HG ENV: 538-741 D GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 348-431 L TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLY ALI: 282-366 GVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNN ENV: 231-380 DISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 662-846 LGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM ALI: 551-738 PKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF ENV: 536-741 NED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 633-817 ASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM ALI: 551-738 PKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF ENV: 484-741 IHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MLLKENTAK DKGIDSTLDL LKEGYLFIKN RADHYQSDLF ETRLMGQRII CMTGEEAARI FYDSDKFKRQ GAAPKRVQET LLGENAIQTL DGESHLHRKK LFMLLTNQVQ QKRLAELTTE KWEASASKWH TKSIVLFNEA NEILCQVACH WAGVPLMESD IKNRAEDFSS MIDSFGAVGP RHWKGKKARN TIEAWIKEII ENVRSGRIRA EEGSPLHEIA FYIDVNGQQM PAEMAAIELI NILRPIVAIS TFITFSALAL YEHSEYREKL QSKDIRYLEM FTQEVRRYYP FAPFVGARVR KDFLWNNCEF KKEMLVLLDI YGTNHDSRIW QKPYEFIPDR FRSYKGNLFD FIPQGGGDPS STHRCPGEGI TLEIMKTSLD FLSTKIDFTV PDQDLSYSLS KIPTLPKSGF IIDNINLKL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
PF00067: 270-377 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MLLKENTAK DKGIDSTLDL LKEGYLFIKN RADHYQSDLF ETRLMGQRII CMTGEEAARI FYDSDKFKRQ GAAPKRVQET LLGENAIQTL DGESHLHRKK LFMLLTNQVQ QKRLAELTTE KWEASASKWH TKSIVLFNEA NEILCQVACH WAGVPLMESD IKNRAEDFSS MIDSFGAVGP RHWKGKKARN TIEAWIKEII ENVRSGRIRA EEGSPLHEIA FYIDVNGQQM PAEMAAIELI NILRPIVAIS TFITFSALAL YEHSEYREKL QSKDIRYLEM FTQEVRRYYP FAPFVGARVR KDFLWNNCEF KKEMLVLLDI YGTNHDSRIW QKPYEFIPDR FRSYKGNLFD FIPQGGGDPS STHRCPGEGI TLEIMKTSLD FLSTKIDFTV PDQDLSYSLS KIPTLPKSGF IIDNINLKL HMM: 268-356 L QSKDIRYLEM FTQEVRRYYP FAPFVGARVR KDFLWNNCEF KKEMLVLLDI YGTNHDSRIW QKPYEFIPDR FRSYKGNLFD FIPQGGGD ALI: 253-342 FSALAL YEHSEYREKL QSKDIRYLEM FTQEVRRYYP FAPFVGARVR KDFLWNNCEF KKEMLVLLDI YGTNHDSRIW QKPYEFIPDR FRSY ENV: 250-367 FITFSALAL YEHSEYREKL QSKDIRYLEM FTQEVRRYYP FAPFVGARVR KDFLWNNCEF KKEMLVLLDI YGTNHDSRIW QKPYEFIPDR FRSYKGNLFD FIPQGGGDPS STHRCPGEG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MDFNLTREQ ELVRQMVREF AENEVKPIAA EIDETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKERK QFGRSLDKFQ GLAWMMADMD VAIESARYLV YKAAYLKQAG LPYTVDAARA KLHAANVAMD VTTKAVQLFG GYGYTKDYPV ERMMRDAKIT EIYEGTSEVQ KLVISGKIFR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-217 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 228-374 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌
Sequence: MDFNLTREQ ELVRQMVREF AENEVKPIAA EIDETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKERK QFGRSLDKFQ GLAWMMADMD VAIESARYLV YKAAYLKQAG LPYTVDAARA KLHAANVAMD VTTKAVQLFG GYGYTKDYPV ERMMRDAKIT EIYEGTSEVQ KLVISGKIFR HMM: 31-279 DETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKERK QFGRSLDKFQ G ALI: 24-267 KPIAA EIDETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKER ENV: 6-299 REQ ELVRQMVREF AENEVKPIAA EIDETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKERK QFGRSLDKFQ GLAWMMADMD VAIESARYLV Y Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MDFNLTREQ ELVRQMVREF AENEVKPIAA EIDETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKERK QFGRSLDKFQ GLAWMMADMD VAIESARYLV YKAAYLKQAG LPYTVDAARA KLHAANVAMD VTTKAVQLFG GYGYTKDYPV ERMMRDAKIT EIYEGTSEVQ KLVISGKIFR HMM: 344-392 KDYPV ERMMRDAKIT EIYEGTSEVQ KLVISGKIFR ALI: 315-363 AARA KLHAANVAMD VTTKAVQLFG GYGYTKDYPV ERMMRDAKIT EIYEG ENV: 304-376 LKQAG LPYTVDAARA KLHAANVAMD VTTKAVQLFG GYGYTKDYPV ERMMRDAKIT EIYEGTSEVQ KLVISGKI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MIKNPILRG FNPDPSICRA DTDYYIATST FEWFPGVQIH HSKDLVNWHL VAHPLNRTSL LDMKGNPNSG GIWAPDLSYH DGKFWLIYTD VKVTDGMWKD CHNYLTTCES VDGVWSDPIT LNGSGFDASL FHDNDGKKYL VNMYWDQRTY NHNFYGIVLQ EYSDKEKKLI GKAKIIYKGT DIKYTEGPHI YHIGDYYYLF TAEGGTTYEH SETVARSKNI DGPYEIDPEY PLLTSWHDPR NSLQKCGHAS LVHTHTDEWY LAHLVGRPLP VGNQPVLEQR GYCPLGRETS IQRIEWVDNW PRVVGGKQGS VNVEAPKIPE VKWEKTYDEK DNFDSDKLNI NFQSLRIPLT ENIASLKAKK GNLRLYGKES LTSTFTQAFI ARRWQSFKFD ASTSVSFSPD TFQQAAGLTC YYNTENWSTI QVTWNEDKGR VIDIVCCDNF HFDMPLKSNV IPIPKDVEYI HLKVEVRVET YQYSYSFDGI NWSKVPAIFE SRKLSDDYVQ GGGFFTGAFV GINCIDITGN NKPADFDYFC YKEL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
PF04616: 1-300 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
PF17851: 328-531 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MIKNPILRG FNPDPSICRA DTDYYIATST FEWFPGVQIH HSKDLVNWHL VAHPLNRTSL LDMKGNPNSG GIWAPDLSYH DGKFWLIYTD VKVTDGMWKD CHNYLTTCES VDGVWSDPIT LNGSGFDASL FHDNDGKKYL VNMYWDQRTY NHNFYGIVLQ EYSDKEKKLI GKAKIIYKGT DIKYTEGPHI YHIGDYYYLF TAEGGTTYEH SETVARSKNI DGPYEIDPEY PLLTSWHDPR NSLQKCGHAS LVHTHTDEWY LAHLVGRPLP VGNQPVLEQR GYCPLGRETS IQRIEWVDNW PRVVGGKQGS VNVEAPKIPE VKWEKTYDEK DNFDSDKLNI NFQSLRIPLT ENIASLKAKK GNLRLYGKES LTSTFTQAFI ARRWQSFKFD ASTSVSFSPD TFQQAAGLTC YYNTENWSTI QVTWNEDKGR VIDIVCCDNF HFDMPLKSNV IPIPKDVEYI HLKVEVRVET YQYSYSFDGI NWSKVPAIFE SRKLSDDYVQ GGGFFTGAFV GINCIDITGN NKPADFDYFC YKEL HMM: 40-77 SKDLVNWHL VAHPLNRTSL LDMKGNPNSG GIWAPDLSY ALI: 449-486 IPIPKDVEYI HLKVEVRVET YQYSYSFDGI NWSKVPAI ENV: 433-499 VCCDNF HFDMPLKSNV IPIPKDVEYI HLKVEVRVET YQYSYSFDGI NWSKVPAIFE SRKLSDDYVQ G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MLDLKRIRT NPEEIKKALT NRGEDFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKSGQ NADELLAEMK KISDDIKGID AKVSEIDEKM QYIMLRIPNI PHPSVPEGKS DEENVEIRKW GEPRKFDFEF KAHWDIGTDL GLLDFERGGK VAGSRFTFYK GLGARLERAV INYFLDTHVE KHGYTEILPP YMVNRVSMTG TGQLPKFEED AFKVDNGFFL IPTAEVPVTN MFRDEILKAE DLPYKFAAYS ACFRSEAGSA GRDTRGLVRQ HQFNKVELVK FAKPEESYDE LEKLTHDAEE ILQILNIPYR VVRICKGDLG FTAALKYDIE VWMPSYGRYV EISSCSNFED FQARRANIKF RRDPKAKPEF VHTLNGSGLA VGRTVAAILE NYQNEDGSVN VPEALKKYIG KDVIR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
PF02403: 0-110 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
PF00587: 223-401 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
Sequence: MLDLKRIRT NPEEIKKALT NRGEDFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKSGQ NADELLAEMK KISDDIKGID AKVSEIDEKM QYIMLRIPNI PHPSVPEGKS DEENVEIRKW GEPRKFDFEF KAHWDIGTDL GLLDFERGGK VAGSRFTFYK GLGARLERAV INYFLDTHVE KHGYTEILPP YMVNRVSMTG TGQLPKFEED AFKVDNGFFL IPTAEVPVTN MFRDEILKAE DLPYKFAAYS ACFRSEAGSA GRDTRGLVRQ HQFNKVELVK FAKPEESYDE LEKLTHDAEE ILQILNIPYR VVRICKGDLG FTAALKYDIE VWMPSYGRYV EISSCSNFED FQARRANIKF RRDPKAKPEF VHTLNGSGLA VGRTVAAILE NYQNEDGSVN VPEALKKYIG KDVIR HMM: 53-94 RNKDSG EIAKLKKSGQ NADELLAEMK KISDDIKGID AKVSEI ALI: 23-66 DFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKS ENV: 15-85 KALT NRGEDFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKSGQ NADELLAEMK KISDDIK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
Sequence: MLDLKRIRT NPEEIKKALT NRGEDFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKSGQ NADELLAEMK KISDDIKGID AKVSEIDEKM QYIMLRIPNI PHPSVPEGKS DEENVEIRKW GEPRKFDFEF KAHWDIGTDL GLLDFERGGK VAGSRFTFYK GLGARLERAV INYFLDTHVE KHGYTEILPP YMVNRVSMTG TGQLPKFEED AFKVDNGFFL IPTAEVPVTN MFRDEILKAE DLPYKFAAYS ACFRSEAGSA GRDTRGLVRQ HQFNKVELVK FAKPEESYDE LEKLTHDAEE ILQILNIPYR VVRICKGDLG FTAALKYDIE VWMPSYGRYV EISSCSNFED FQARRANIKF RRDPKAKPEF VHTLNGSGLA VGRTVAAILE NYQNEDGSVN VPEALKKYIG KDVIR HMM: 8-78 T NPEEIKKALT NRGEDFDISV IDELVSLDEE RRKNLVEVEN LKSKRNKDSG EIAKLKKSGQ NADELLAEMK ALI: 289-359 FAKPEESYDE LEKLTHDAEE ILQILNIPYR VVRICKGDLG FTAALKYDIE VWMPSYGRYV EISSCSNFED F ENV: 283-381 KVELVK FAKPEESYDE LEKLTHDAEE ILQILNIPYR VVRICKGDLG FTAALKYDIE VWMPSYGRYV EISSCSNFED FQARRANIKF RRDPKAKPEF VHT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420
Sequence: MKKYVCVVC GYIYDPAEGD PDNGVNPGTS FEDIPDDWVC PLCGVGKDQF EPSEE
10 20 30 40 50
PF00301: 2-49 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MKKYVCVVC GYIYDPAEGD PDNGVNPGTS FEDIPDDWVC PLCGVGKDQF EPSEE HMM: 424-469 ALI: 2-47 KYVCVVC GYIYDPAEGD PDNGVNPGTS FEDIPDDWVC PLCGVGKDQ ENV: 1-54 KKYVCVVC GYIYDPAEGD PDNGVNPGTS FEDIPDDWVC PLCGVGKDQF EPSEE Position: 10 20 30 40 50
Sequence: MKKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGNITSVK LTDTEKIIET SDTIYKPKSV IIATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVYI GTMPKTELFK DFIDLTELGH IKTNENLETN IKGVFAAGDV REKEIRQLTT AVNDGSIASL MAEKYIRNS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
PF07992: 7-294 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌
Sequence: MKKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGNITSVK LTDTEKIIET SDTIYKPKSV IIATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVYI GTMPKTELFK DFIDLTELGH IKTNENLETN IKGVFAAGDV REKEIRQLTT AVNDGSIASL MAEKYIRNS HMM: 2-44 KEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIR ALI: 3-42 EKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQ ENV: 1-64 KKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MKKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGNITSVK LTDTEKIIET SDTIYKPKSV IIATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVYI GTMPKTELFK DFIDLTELGH IKTNENLETN IKGVFAAGDV REKEIRQLTT AVNDGSIASL MAEKYIRNS HMM: 154-225 GNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGE ALI: 122-193 PEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKH ENV: 111-237 ATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MKKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGNITSVK LTDTEKIIET SDTIYKPKSV IIATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVYI GTMPKTELFK DFIDLTELGH IKTNENLETN IKGVFAAGDV REKEIRQLTT AVNDGSIASL MAEKYIRNS HMM: 2-43 KEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQI ALI: 4-42 KILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQ ENV: 3-83 EKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MKKEKILDL VIIGAGPAGL TAGIYSSRAK LDFIILENEL VGGQIRETPS IENFPGFDSI SGADLADKMQ EHAEKAGAVI DEFGNITSVK LTDTEKIIET SDTIYKPKSV IIATGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEKSS LKADAIFVYI GTMPKTELFK DFIDLTELGH IKTNENLETN IKGVFAAGDV REKEIRQLTT AVNDGSIASL MAEKYIRNS HMM: 152-226 GGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIENIVL ENSKTGEK ALI: 122-195 PEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNN ENV: 112-214 TGSKSRP LPVPEEKKLR GKGIHYCELC DGAMYDGKDI VVVGGGNSAI DAAIFLTKYA KNLTVVHRSE KLRAEMRSQD ELFKHNNVKL LLNTQIKHVE GENSIE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MNNYRNVFK PIKIGNILVK NRIEVSPAEP FLASKDGYVT QEFIEWTRAM AKGGAGIVTI GDSPVNAEYA KSSPYVIDMS KDTIVNGLYT LTEVIHRYGA KASLELNLRA DYTPTDMTKE KIKQVINDFA DAAFRCKQAG MDMVMIHGGH GHLVAQFFSP FYNKRTDEYS TSNMENRTRF ARELLDAVRE KIGNDMAIEY RISADELNEH GVRIGEALEF AKIIQEKIDL IHVSVGDLYK PEAIPFMIQP TYIPQGINVN YAERFKKELN IPVTTVGSLD IDIAEQVIIE EKADMVAMIR AFIADSDFVN KAKYGEERTI RPCIRCTTCV GQSPHAYCIP IRCAVNPMNG REREFMNMPF QETKKKVVVI GGGPAGMEAA RDAAKRGHKV IIMEKSDELG GFLKVASASS LKNDMRRYLQ WAVNMTMESQ NIEVRLNTEA TVENVKAENP DAIVIAVGSK VFIPDIPGVE KKNVIWAGDI AQRKMDTGNK VIVVGAGLTG SEAALLLARK GKKVTLVDMR PLKDLDANSP AIATSTLRSM LQSEDVKTIT GIKLKEISDE DAVFVDERQQ EHVICCDTLV LALGVTPRTE VVNKFKELVK EVYVIGDCNN KSGNLIKATT EGFFAAMSI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620
PF00724: 110-315 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF07992: 363-608 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MNNYRNVFK PIKIGNILVK NRIEVSPAEP FLASKDGYVT QEFIEWTRAM AKGGAGIVTI GDSPVNAEYA KSSPYVIDMS KDTIVNGLYT LTEVIHRYGA KASLELNLRA DYTPTDMTKE KIKQVINDFA DAAFRCKQAG MDMVMIHGGH GHLVAQFFSP FYNKRTDEYS TSNMENRTRF ARELLDAVRE KIGNDMAIEY RISADELNEH GVRIGEALEF AKIIQEKIDL IHVSVGDLYK PEAIPFMIQP TYIPQGINVN YAERFKKELN IPVTTVGSLD IDIAEQVIIE EKADMVAMIR AFIADSDFVN KAKYGEERTI RPCIRCTTCV GQSPHAYCIP IRCAVNPMNG REREFMNMPF QETKKKVVVI GGGPAGMEAA RDAAKRGHKV IIMEKSDELG GFLKVASASS LKNDMRRYLQ WAVNMTMESQ NIEVRLNTEA TVENVKAENP DAIVIAVGSK VFIPDIPGVE KKNVIWAGDI AQRKMDTGNK VIVVGAGLTG SEAALLLARK GKKVTLVDMR PLKDLDANSP AIATSTLRSM LQSEDVKTIT GIKLKEISDE DAVFVDERQQ EHVICCDTLV LALGVTPRTE VVNKFKELVK EVYVIGDCNN KSGNLIKATT EGFFAAMSI HMM: 175-245 RTRF ARELLDAVRE KIGNDMAIEY RISADELNEH GVRIGEALEF AKIIQEKIDL IHVSVGDLYK PEAIPFM ALI: 360-431 ETKKKVVVI GGGPAGMEAA RDAAKRGHKV IIMEKSDELG GFLKVASASS LKNDMRRYLQ WAVNMTMESQ NIE ENV: 354-454 MNMPF QETKKKVVVI GGGPAGMEAA RDAAKRGHKV IIMEKSDELG GFLKVASASS LKNDMRRYLQ WAVNMTMESQ NIEVRLNTEA TVENVKAENP DAIVIA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620
Sequence: MNNYRNVFK PIKIGNILVK NRIEVSPAEP FLASKDGYVT QEFIEWTRAM AKGGAGIVTI GDSPVNAEYA KSSPYVIDMS KDTIVNGLYT LTEVIHRYGA KASLELNLRA DYTPTDMTKE KIKQVINDFA DAAFRCKQAG MDMVMIHGGH GHLVAQFFSP FYNKRTDEYS TSNMENRTRF ARELLDAVRE KIGNDMAIEY RISADELNEH GVRIGEALEF AKIIQEKIDL IHVSVGDLYK PEAIPFMIQP TYIPQGINVN YAERFKKELN IPVTTVGSLD IDIAEQVIIE EKADMVAMIR AFIADSDFVN KAKYGEERTI RPCIRCTTCV GQSPHAYCIP IRCAVNPMNG REREFMNMPF QETKKKVVVI GGGPAGMEAA RDAAKRGHKV IIMEKSDELG GFLKVASASS LKNDMRRYLQ WAVNMTMESQ NIEVRLNTEA TVENVKAENP DAIVIAVGSK VFIPDIPGVE KKNVIWAGDI AQRKMDTGNK VIVVGAGLTG SEAALLLARK GKKVTLVDMR PLKDLDANSP AIATSTLRSM LQSEDVKTIT GIKLKEISDE DAVFVDERQQ EHVICCDTLV LALGVTPRTE VVNKFKELVK EVYVIGDCNN KSGNLIKATT EGFFAAMSI HMM: 149-211 GHLVAQFFSP FYNKRTDEYS TSNMENRTRF ARELLDAVRE KIGNDMAIEY RISADELNEH GVR ALI: 460-520 FIPDIPGVE KKNVIWAGDI AQRKMDTGNK VIVVGAGLTG SEAALLLARK GKKVTLVDMR PL ENV: 420-549 AVNMTMESQ NIEVRLNTEA TVENVKAENP DAIVIAVGSK VFIPDIPGVE KKNVIWAGDI AQRKMDTGNK VIVVGAGLTG SEAALLLARK GKKVTLVDMR PLKDLDANSP AIATSTLRSM LQSEDVKTIT G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620
Sequence: MSYDVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKRKCPIDGK KIKACINCSV CNIMNGYGGA GSLSDGKYNI TNNFGGDLHK YVGAEEAIDL MNYVDSVLCS MGGEDAKLYS TENSKLKAKA LQYDLHLLDA KVRHLGTDRN LIIMANIFDF LKDKMDIIFD TEVLNIYKGD ELFNIETSNK TFSSKELILA TGRSGSKWIS DMCAKVGIKT KSNRVDIGVR VELPAEVFSH ITDAVYESKI VYKTKKYNDM VRTFCMNPYG EVVNENTNGI ITVNGHSYAN PELRTENTNF ALLVTNNFTE PFEDSNEYGA SIARLSNMLG GGVLVQRFGD LVNGRRTNEH RMEKSFTTPT LKATPGDLGL VIPKRQLDDI IEMIYALNNI APGTANEDTL LYGVEVKFYN SKVEVDKNLE TKIKGLYILG DGSGVTHSLS QAAASGVYIA RILAEKYR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450
Sequence: MSYDVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKRKCPIDGK KIKACINCSV CNIMNGYGGA GSLSDGKYNI TNNFGGDLHK YVGAEEAIDL MNYVDSVLCS MGGEDAKLYS TENSKLKAKA LQYDLHLLDA KVRHLGTDRN LIIMANIFDF LKDKMDIIFD TEVLNIYKGD ELFNIETSNK TFSSKELILA TGRSGSKWIS DMCAKVGIKT KSNRVDIGVR VELPAEVFSH ITDAVYESKI VYKTKKYNDM VRTFCMNPYG EVVNENTNGI ITVNGHSYAN PELRTENTNF ALLVTNNFTE PFEDSNEYGA SIARLSNMLG GGVLVQRFGD LVNGRRTNEH RMEKSFTTPT LKATPGDLGL VIPKRQLDDI IEMIYALNNI APGTANEDTL LYGVEVKFYN SKVEVDKNLE TKIKGLYILG DGSGVTHSLS QAAASGVYIA RILAEKYR HMM: 6-39 IVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL E ALI: 3-36 DVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGH ENV: 1-41 SYDVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450
Sequence: MSYDVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKRKCPIDGK KIKACINCSV CNIMNGYGGA GSLSDGKYNI TNNFGGDLHK YVGAEEAIDL MNYVDSVLCS MGGEDAKLYS TENSKLKAKA LQYDLHLLDA KVRHLGTDRN LIIMANIFDF LKDKMDIIFD TEVLNIYKGD ELFNIETSNK TFSSKELILA TGRSGSKWIS DMCAKVGIKT KSNRVDIGVR VELPAEVFSH ITDAVYESKI VYKTKKYNDM VRTFCMNPYG EVVNENTNGI ITVNGHSYAN PELRTENTNF ALLVTNNFTE PFEDSNEYGA SIARLSNMLG GGVLVQRFGD LVNGRRTNEH RMEKSFTTPT LKATPGDLGL VIPKRQLDDI IEMIYALNNI APGTANEDTL LYGVEVKFYN SKVEVDKNLE TKIKGLYILG DGSGVTHSLS QAAASGVYIA RILAEKYR HMM: 5-41 IIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKR ALI: 3-39 DVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL E ENV: 1-43 SYDVIIVG AGASGIFTAY ELVKKNPKVN ILMIEKGHSL EKRKC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450
Sequence: MDNPNLLSE EANRCLLCKN PRCKANCPIN TPIPEIISLY KEGKIMEAGE ILFNNNPLSV ICSLVCIHED QCKGNCVRGI KSEPIKFHEI EEEISEKYLK EAKLKNVQKD KDRIAIVGGG PAGITVAFVL ANKGYNVTIF EAHDKIGGVL RYGIPEYRLT KKLVDKLEER LIEVGVKIRP NTVIGPVISL DRLLEDSYKA VFIGTGVWNP KTLDVKGETL GNVHFAIDYL KSPESYRLGK KVAVIGAGNV AMDAARTAKR NGAEVTILYR KSFNEMPASK QEIRETKEDG VEFKLFRAPI EITEEGIKVA FTENVTDAEG KIRTKIIEGK EEFFECDSVV VAVSQAPKDN IVSNTTGLDT KWGLIVTDEK GNTTKKGTFA CGDVVTGAKT VVEAAAQAKV VAETIDEYCK NN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
PF14691: 7-98 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF13450: 114-149 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
PF07992: 194-397 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MDNPNLLSE EANRCLLCKN PRCKANCPIN TPIPEIISLY KEGKIMEAGE ILFNNNPLSV ICSLVCIHED QCKGNCVRGI KSEPIKFHEI EEEISEKYLK EAKLKNVQKD KDRIAIVGGG PAGITVAFVL ANKGYNVTIF EAHDKIGGVL RYGIPEYRLT KKLVDKLEER LIEVGVKIRP NTVIGPVISL DRLLEDSYKA VFIGTGVWNP KTLDVKGETL GNVHFAIDYL KSPESYRLGK KVAVIGAGNV AMDAARTAKR NGAEVTILYR KSFNEMPASK QEIRETKEDG VEFKLFRAPI EITEEGIKVA FTENVTDAEG KIRTKIIEGK EEFFECDSVV VAVSQAPKDN IVSNTTGLDT KWGLIVTDEK GNTTKKGTFA CGDVVTGAKT VVEAAAQAKV VAETIDEYCK NN HMM: 7-45 SE EANRCLLCKN PRCKANCPIN TPIPEIISLY KEGKIME ALI: 112-148 IAIVGGG PAGITVAFVL ANKGYNVTIF EAHDKIGGVL ENV: 104-156 NVQKD KDRIAIVGGG PAGITVAFVL ANKGYNVTIF EAHDKIGGVL RYGIPEYR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MDNPNLLSE EANRCLLCKN PRCKANCPIN TPIPEIISLY KEGKIMEAGE ILFNNNPLSV ICSLVCIHED QCKGNCVRGI KSEPIKFHEI EEEISEKYLK EAKLKNVQKD KDRIAIVGGG PAGITVAFVL ANKGYNVTIF EAHDKIGGVL RYGIPEYRLT KKLVDKLEER LIEVGVKIRP NTVIGPVISL DRLLEDSYKA VFIGTGVWNP KTLDVKGETL GNVHFAIDYL KSPESYRLGK KVAVIGAGNV AMDAARTAKR NGAEVTILYR KSFNEMPASK QEIRETKEDG VEFKLFRAPI EITEEGIKVA FTENVTDAEG KIRTKIIEGK EEFFECDSVV VAVSQAPKDN IVSNTTGLDT KWGLIVTDEK GNTTKKGTFA CGDVVTGAKT VVEAAAQAKV VAETIDEYCK NN HMM: 170-210 IEVGVKIRP NTVIGPVISL DRLLEDSYKA VFIGTGVWNP KT ALI: 231-270 PESYRLGK KVAVIGAGNV AMDAARTAKR NGAEVTILYR KS ENV: 208-283 P KTLDVKGETL GNVHFAIDYL KSPESYRLGK KVAVIGAGNV AMDAARTAKR NGAEVTILYR KSFNEMPASK QEIRE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MNRNLVVAL AGNPNCGKTS LFNELTGSKQ HVGNWPGVTV EKKEGKLKFE GREITIVDLP GTYSLGAYSE DEVVARDFIL KDKPDVVINV VDACNLERNL YLTTQILETG AKVVLALNMM DEANTRNIDI NIEKLQKSIG IPVVPTVATK KQGIKELVKN AIKLGDSESE ELYTIDYGSD IQKEVDGIKA AIDEASVTLE YPKAWVSLKL LENDDYIRKY IDNSIKDDEV KHKVSEGIEN LTSIIGYEPD AFIVDKRYEL ISKFVKNSVK KNEVQEESTS DKIDKVLTNK FLGIPIFAII MFAVYQVSIN FGNGTLSDLI NDSLGQLGTN IAFTLDGFGV PKIIGAFVRD GVFAGVGSVL GFFPMILIMF FLISLLEDSG YMARAAYVMD RLMSAVGLHG KTAVSLIVGS GCNVAGIMSA RTLESKKDRM IAILITPFIS CPARLTVYGV FVGAFFAKQK LGIFSLGGII IFLLYALGIF VAICAGKFFS SKVFEGETSY FVMELPPYRL PTLKGILIHM WEKSGHFLKK AGTIILGVCI IVWILADLPA GVEYGSKDSL LGIIGTFIAP IFKPAGFGSW QAGVALITGF AAKEAVVGTL GTIYGVNEGT QLFHAIHNTF TPLSAISFMI MTLLYVPCVA TIGAVKSETN SNKWTVAVII YTCVIGWVLA TIFYQVGRLL GYV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF02421: 5-159 ◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
PF17910: 175-269 ◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
PF07670: 526-650 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
PF07664: 469-522 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MNRNLVVAL AGNPNCGKTS LFNELTGSKQ HVGNWPGVTV EKKEGKLKFE GREITIVDLP GTYSLGAYSE DEVVARDFIL KDKPDVVINV VDACNLERNL YLTTQILETG AKVVLALNMM DEANTRNIDI NIEKLQKSIG IPVVPTVATK KQGIKELVKN AIKLGDSESE ELYTIDYGSD IQKEVDGIKA AIDEASVTLE YPKAWVSLKL LENDDYIRKY IDNSIKDDEV KHKVSEGIEN LTSIIGYEPD AFIVDKRYEL ISKFVKNSVK KNEVQEESTS DKIDKVLTNK FLGIPIFAII MFAVYQVSIN FGNGTLSDLI NDSLGQLGTN IAFTLDGFGV PKIIGAFVRD GVFAGVGSVL GFFPMILIMF FLISLLEDSG YMARAAYVMD RLMSAVGLHG KTAVSLIVGS GCNVAGIMSA RTLESKKDRM IAILITPFIS CPARLTVYGV FVGAFFAKQK LGIFSLGGII IFLLYALGIF VAICAGKFFS SKVFEGETSY FVMELPPYRL PTLKGILIHM WEKSGHFLKK AGTIILGVCI IVWILADLPA GVEYGSKDSL LGIIGTFIAP IFKPAGFGSW QAGVALITGF AAKEAVVGTL GTIYGVNEGT QLFHAIHNTF TPLSAISFMI MTLLYVPCVA TIGAVKSETN SNKWTVAVII YTCVIGWVLA TIFYQVGRLL GYV HMM: 60-105 TYSLGAYSE DEVVARDFIL KDKPDVVINV VDACNLERNL YLTTQIL ALI: 195-239 VTLE YPKAWVSLKL LENDDYIRKY IDNSIKDDEV KHKVSEGIEN L ENV: 179-268 IQKEVDGIKA AIDEASVTLE YPKAWVSLKL LENDDYIRKY IDNSIKDDEV KHKVSEGIEN LTSIIGYEPD AFIVDKRYEL ISKFVKNSVK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MENHDLVIV GGGISGLQAA ISAKKSGVQD IVLIEAEDSL GGILNQCIYT GFGMEDFKEE LTGTEYVQRF IDEFLELNIE YKLNTTVIKI SKNKVITAVS PNEGIIEIKA CSIIFAAGAV EKPQKSIRVL TKDLSGIYSA LTVGRFINIH GYMPGKSIVI LGANKIGNAL ANRIFIEGGK VKAVIDSEVG FDERNEIIEF LAEINIPFLY NYNIVKIKGS ERIEGIYISD ENGEKFISCD TLILALKLNP NDKILREANI KILNKERNEI NTNVPGVFIV GNALYIHESN EGSPLENRKA GEMSAEYIRA TL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310
PF07992: 3-283 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌
Sequence: MENHDLVIV GGGISGLQAA ISAKKSGVQD IVLIEAEDSL GGILNQCIYT GFGMEDFKEE LTGTEYVQRF IDEFLELNIE YKLNTTVIKI SKNKVITAVS PNEGIIEIKA CSIIFAAGAV EKPQKSIRVL TKDLSGIYSA LTVGRFINIH GYMPGKSIVI LGANKIGNAL ANRIFIEGGK VKAVIDSEVG FDERNEIIEF LAEINIPFLY NYNIVKIKGS ERIEGIYISD ENGEKFISCD TLILALKLNP NDKILREANI KILNKERNEI NTNVPGVFIV GNALYIHESN EGSPLENRKA GEMSAEYIRA TL HMM: 5-53 LVIV GGGISGLQAA ISAKKSGVQD IVLIEAEDSL GGILNQCIYT GFGME ALI: 4-51 DLVIV GGGISGLQAA ISAKKSGVQD IVLIEAEDSL GGILNQCIYT GFG ENV: 1-58 ENHDLVIV GGGISGLQAA ISAKKSGVQD IVLIEAEDSL GGILNQCIYT GFGMEDFKEE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310
Sequence: MKDNKINIL FLSWRDIKCP KSGGAEVFTH EMLKRLDFNK YDITHFSPTF EGAKEKEIID NVTYIRRGNI LSVISEAKKY YKTNKDEIDF VVDQCNTHKF FTPLWVPKKK RIFFIHQLTR EIWHINARFP ISTLGYLFET PTLRLYKNDY TITVSDSTKK DLIDIGFDRD KVTIFPEGIN FKPWDKDSLL KEKDNIFGYI GRFVNYKGID AAVKAYCILK KDYPNSKLWI IGKKKDDYIE KVLLPILKEN NITYGNRGQN RDITFWGFVS EKEKLSLMSK MKALLFPSIR EGFGLTVIEA GAVGTPTVVY NSKGLVDAVD KGKAGYLCEE NTPENLYYFM KNILENENEY GLKRKNAHDF SLKFNWDSTS KYFDDFINKL NEKSLKK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF13439: 21-179 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
PF00534: 182-349 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MKDNKINIL FLSWRDIKCP KSGGAEVFTH EMLKRLDFNK YDITHFSPTF EGAKEKEIID NVTYIRRGNI LSVISEAKKY YKTNKDEIDF VVDQCNTHKF FTPLWVPKKK RIFFIHQLTR EIWHINARFP ISTLGYLFET PTLRLYKNDY TITVSDSTKK DLIDIGFDRD KVTIFPEGIN FKPWDKDSLL KEKDNIFGYI GRFVNYKGID AAVKAYCILK KDYPNSKLWI IGKKKDDYIE KVLLPILKEN NITYGNRGQN RDITFWGFVS EKEKLSLMSK MKALLFPSIR EGFGLTVIEA GAVGTPTVVY NSKGLVDAVD KGKAGYLCEE NTPENLYYFM KNILENENEY GLKRKNAHDF SLKFNWDSTS KYFDDFINKL NEKSLKK HMM: 62-109 YIRRGNI LSVISEAKKY YKTNKDEIDF VVDQCNTHKF FTPLWVPKKK R ALI: 176-222 GIN FKPWDKDSLL KEKDNIFGYI GRFVNYKGID AAVKAYCILK KDYP ENV: 160-243 LIDIGFDRD KVTIFPEGIN FKPWDKDSLL KEKDNIFGYI GRFVNYKGID AAVKAYCILK KDYPNSKLWI IGKKKDDYIE KVLLP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
PF02901: 16-601 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF01228: 616-724 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 290-420 QEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FG ALI: 235-366 PAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNN ENV: 210-381 EVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 481-569 LNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV N ALI: 412-501 IGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALH ENV: 400-512 DYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 644-831 RSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM ALI: 551-740 PKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HG ENV: 538-741 D GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 348-431 L TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLY ALI: 282-366 GVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNN ENV: 231-380 DISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 662-846 LGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM ALI: 551-738 PKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF ENV: 536-741 NED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MIKEWNDFK EGTWVNNIDV RNFIQKNYTP YLGNEDFLQG VTDRTKGLWN KCEKLLLDEI KNQGILKADN KTVSGINSFE AGYIDKENEI IYGLQTDEPL KRMVNPFGGI RMAKQALEAY GYEIDEDVYN IFTKYRKTHN EGVFDAYTEE MKTARHVGLL TGLPDAYGRG RIIGDFRRVA LYGIDCLIEN KKADLKELKG DMTEDLIRRR EEVSEQIKAL KEMKAMALKY GIDISKPAAN SRQAVQFTYL GYLAGIKENN GAAMSLGRVS TFLDIYIERD LKNGVITEKE AQEIIDQFII KLRLERHLRT PEYNELFAGD PNWVTESIGG MGMNGETLVT KNSFRFLHSL TNLGPAPEPN MTVLWSNNLP EPFKKYCSKM SIKTDAIQYE NDDIMRPIYG DDYGIACCVS AMKIGKQMQF FGARCNLAKS LLYAINGGVD EKKFDLVVPH IKRIDDEVLD YDKVKENYFK VMKYVAKLYV NTLNLIHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM HMM: 633-817 ASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGRM ALI: 551-738 PKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF ENV: 484-741 IHYMH DKYAYEKGLM ALHDTDVHRF LACGAAGLSV AVDSLSAIKY AKVKPIRNED GIAVDFEVEG DFPKYGNDDD RVDDIAVEIV NKFMSELRKT AAYRNAEHTL SMLTITSNVM YGKKTGATPD GRKSGEAFAP GANPMHGRDK NGALASLNSV AKIPYRSVCQ DGVSNTFSII PDALGKNEET RANNLSAILD GYFEKGAHHL NVNVLNRETL LDAMENPEKY PTLTIRVSGY AVNFVKLTKE QQMEVVKRTF HGR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MLLKENTAK DKGIDSTLDL LKEGYLFIKN RADHYQSDLF ETRLMGQRII CMTGEEAARI FYDSDKFKRQ GAAPKRVQET LLGENAIQTL DGESHLHRKK LFMLLTNQVQ QKRLAELTTE KWEASASKWH TKSIVLFNEA NEILCQVACH WAGVPLMESD IKNRAEDFSS MIDSFGAVGP RHWKGKKARN TIEAWIKEII ENVRSGRIRA EEGSPLHEIA FYIDVNGQQM PAEMAAIELI NILRPIVAIS TFITFSALAL YEHSEYREKL QSKDIRYLEM FTQEVRRYYP FAPFVGARVR KDFLWNNCEF KKEMLVLLDI YGTNHDSRIW QKPYEFIPDR FRSYKGNLFD FIPQGGGDPS STHRCPGEGI TLEIMKTSLD FLSTKIDFTV PDQDLSYSLS KIPTLPKSGF IIDNINLKL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
PF00067: 270-377 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MLLKENTAK DKGIDSTLDL LKEGYLFIKN RADHYQSDLF ETRLMGQRII CMTGEEAARI FYDSDKFKRQ GAAPKRVQET LLGENAIQTL DGESHLHRKK LFMLLTNQVQ QKRLAELTTE KWEASASKWH TKSIVLFNEA NEILCQVACH WAGVPLMESD IKNRAEDFSS MIDSFGAVGP RHWKGKKARN TIEAWIKEII ENVRSGRIRA EEGSPLHEIA FYIDVNGQQM PAEMAAIELI NILRPIVAIS TFITFSALAL YEHSEYREKL QSKDIRYLEM FTQEVRRYYP FAPFVGARVR KDFLWNNCEF KKEMLVLLDI YGTNHDSRIW QKPYEFIPDR FRSYKGNLFD FIPQGGGDPS STHRCPGEGI TLEIMKTSLD FLSTKIDFTV PDQDLSYSLS KIPTLPKSGF IIDNINLKL HMM: 268-356 L QSKDIRYLEM FTQEVRRYYP FAPFVGARVR KDFLWNNCEF KKEMLVLLDI YGTNHDSRIW QKPYEFIPDR FRSYKGNLFD FIPQGGGD ALI: 253-342 FSALAL YEHSEYREKL QSKDIRYLEM FTQEVRRYYP FAPFVGARVR KDFLWNNCEF KKEMLVLLDI YGTNHDSRIW QKPYEFIPDR FRSY ENV: 250-367 FITFSALAL YEHSEYREKL QSKDIRYLEM FTQEVRRYYP FAPFVGARVR KDFLWNNCEF KKEMLVLLDI YGTNHDSRIW QKPYEFIPDR FRSYKGNLFD FIPQGGGDPS STHRCPGEG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MDFNLTREQ ELVRQMVREF AENEVKPIAA EIDETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKERK QFGRSLDKFQ GLAWMMADMD VAIESARYLV YKAAYLKQAG LPYTVDAARA KLHAANVAMD VTTKAVQLFG GYGYTKDYPV ERMMRDAKIT EIYEGTSEVQ KLVISGKIFR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-217 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 228-374 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌
Sequence: MDFNLTREQ ELVRQMVREF AENEVKPIAA EIDETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKERK QFGRSLDKFQ GLAWMMADMD VAIESARYLV YKAAYLKQAG LPYTVDAARA KLHAANVAMD VTTKAVQLFG GYGYTKDYPV ERMMRDAKIT EIYEGTSEVQ KLVISGKIFR HMM: 31-279 DETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKERK QFGRSLDKFQ G ALI: 24-267 KPIAA EIDETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKER ENV: 6-299 REQ ELVRQMVREF AENEVKPIAA EIDETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKERK QFGRSLDKFQ GLAWMMADMD VAIESARYLV Y Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MDFNLTREQ ELVRQMVREF AENEVKPIAA EIDETERFPM ENVKKMGQYG MMGIPFSKEY GGAGGDVLSY IIAVEELSKV CGTTGVILSA HTSLCASLIN EHGTEEQKQK YLVPLAKGEK IGAYGLTEPN AGTDSGAQQT VAVLEGDHYV INGSKIFITN GGVADTFVIF AMTDRTKGTK GISAFIIEKG FKGFSIGKVE QKLGIRASST TELVFEDMIV PVENMIGKEG KGFPIAMKTL DGGRIGIAAQ ALGIAEGAFN EARAYMKERK QFGRSLDKFQ GLAWMMADMD VAIESARYLV YKAAYLKQAG LPYTVDAARA KLHAANVAMD VTTKAVQLFG GYGYTKDYPV ERMMRDAKIT EIYEGTSEVQ KLVISGKIFR HMM: 344-392 KDYPV ERMMRDAKIT EIYEGTSEVQ KLVISGKIFR ALI: 315-363 AARA KLHAANVAMD VTTKAVQLFG GYGYTKDYPV ERMMRDAKIT EIYEG ENV: 304-376 LKQAG LPYTVDAARA KLHAANVAMD VTTKAVQLFG GYGYTKDYPV ERMMRDAKIT EIYEGTSEVQ KLVISGKI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MIKNPILRG FNPDPSICRA DTDYYIATST FEWFPGVQIH HSKDLVNWHL VAHPLNRTSL LDMKGNPNSG GIWAPDLSYH DGKFWLIYTD VKVTDGMWKD CHNYLTTCES VDGVWSDPIT LNGSGFDASL FHDNDGKKYL VNMYWDQRTY NHNFYGIVLQ EYSDKEKKLI GKAKIIYKGT DIKYTEGPHI YHIGDYYYLF TAEGGTTYEH SETVARSKNI DGPYEIDPEY PLLTSWHDPR NSLQKCGHAS LVHTHTDEWY LAHLVGRPLP VGNQPVLEQR GYCPLGRETS IQRIEWVDNW PRVVGGKQGS VNVEAPKIPE VKWEKTYDEK DNFDSDKLNI NFQSLRIPLT ENIASLKAKK GNLRLYGKES LTSTFTQAFI ARRWQSFKFD ASTSVSFSPD TFQQAAGLTC YYNTENWSTI QVTWNEDKGR VIDIVCCDNF HFDMPLKSNV IPIPKDVEYI HLKVEVRVET YQYSYSFDGI NWSKVPAIFE SRKLSDDYVQ GGGFFTGAFV GINCIDITGN NKPADFDYFC YKEL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
PF04616: 1-300 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
PF17851: 328-531 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MIKNPILRG FNPDPSICRA DTDYYIATST FEWFPGVQIH HSKDLVNWHL VAHPLNRTSL LDMKGNPNSG GIWAPDLSYH DGKFWLIYTD VKVTDGMWKD CHNYLTTCES VDGVWSDPIT LNGSGFDASL FHDNDGKKYL VNMYWDQRTY NHNFYGIVLQ EYSDKEKKLI GKAKIIYKGT DIKYTEGPHI YHIGDYYYLF TAEGGTTYEH SETVARSKNI DGPYEIDPEY PLLTSWHDPR NSLQKCGHAS LVHTHTDEWY LAHLVGRPLP VGNQPVLEQR GYCPLGRETS IQRIEWVDNW PRVVGGKQGS VNVEAPKIPE VKWEKTYDEK DNFDSDKLNI NFQSLRIPLT ENIASLKAKK GNLRLYGKES LTSTFTQAFI ARRWQSFKFD ASTSVSFSPD TFQQAAGLTC YYNTENWSTI QVTWNEDKGR VIDIVCCDNF HFDMPLKSNV IPIPKDVEYI HLKVEVRVET YQYSYSFDGI NWSKVPAIFE SRKLSDDYVQ GGGFFTGAFV GINCIDITGN NKPADFDYFC YKEL HMM: 40-77 SKDLVNWHL VAHPLNRTSL LDMKGNPNSG GIWAPDLSY ALI: 449-486 IPIPKDVEYI HLKVEVRVET YQYSYSFDGI NWSKVPAI ENV: 433-499 VCCDNF HFDMPLKSNV IPIPKDVEYI HLKVEVRVET YQYSYSFDGI NWSKVPAIFE SRKLSDDYVQ G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MKYECVVCG WIYDPAIGDP DGGIEPGTAF EDIPDDWVCP LCGVGKEDFE LIEE
10 20 30 40 50
PF00301: 1-48 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
Sequence: MKYECVVCG WIYDPAIGDP DGGIEPGTAF EDIPDDWVCP LCGVGKEDFE LIEE HMM: 425-469 ALI: 2-46 YECVVCG WIYDPAIGDP DGGIEPGTAF EDIPDDWVCP LCGVGKED ENV: 1-53 KYECVVCG WIYDPAIGDP DGGIEPGTAF EDIPDDWVCP LCGVGKEDFE LIEE Position: 10 20 30 40 50
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
PF00384: 0-333 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF01568: 414-521 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 613-684 ALI: 265-334 KLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMG ENV: 256-359 LHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG M Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 837-916 ALI: 411-491 EYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVP ENV: 397-506 SA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 223-313 AGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAV ALI: 3-94 SIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTE ENV: 1-96 TNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 386-470 KDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RR ALI: 96-182 FEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNV ENV: 91-192 NRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 242-329 LFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG I ALI: 6-94 EFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTE ENV: 1-96 TNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 402-480 IPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IA ALI: 97-175 EE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNP ENV: 94-185 EGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 588-700 ALI: 227-335 IV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGY ENV: 199-363 QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 840-921 ALI: 411-493 EYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFH ENV: 399-502 IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 221-311 AKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRK ALI: 4-95 IEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEG ENV: 1-97 TNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 385-463 HKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDD ALI: 97-175 EE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNP ENV: 95-214 GFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 609-680 ALI: 264-333 TKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRM ENV: 230-337 AVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIEEFE NTDLILVTGS NTKEMHPVIS SYMKRGVKKG KTKLIVVDPR KTELAEFAEV WLRQKPGTDV AWLNGMMNVI IAEGLYDKEY VANRTEGFEE LKKAVAAYTP ERVEEISGIP KDDLIAAARL YAKAPAASIA YAMGITQHIN GTEAVKSVAN LAMLCGNIGI EGGGVNPLRG QNNVQGACDM GALPNVFPAY QTVTSPEIRE KFAKAWGVKD LPAKAGLTIV EAVNAASEGK LKALFVMGEN PMVSDPDLHH VKDGLTKLDF LVVQDIFLTE TAALADVVLP AACFAEKEGT FSNTERRVQL VRKAVDPPGD ALPDWQIICG ISKRMGYPMD YPDAEAVFDE ITKVTPSYAG MDYHRLANGG LQWPCPTKEH PGTKVLHKDK FVRGKGLFSA IEWIPPAESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIAALD PLAKIPEYKV CAVRVEKAAG HMM: 821-899 ALI: 412-491 YPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVP ENV: 405-505 AESP DAEYPFMLIT GRVLYQYHTG TMTRKSIGLN ERYPECLIEI NSRDAANMGI QDMDDIRLVT RRGSITAKAK IADVVEKGMV FVPFHFAEAA ANNLTIA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQGACDMG ALPNVFPGYQ QVADPKARAK FEAAWNVKGL PDKPGLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE ISVLAPALGG IKYRRIEKDG LQWPAPTEEH PGTPTLHRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG IQVGDKVRVK SRRGEVVVTA NPTDRVPKGM VWMAFHFRDG CANWLTNPVF DPVTQTAEYK ACAVKIEKA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
PF00384: 1-331 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
PF01568: 415-522 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MTNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQGACDMG ALPNVFPGYQ QVADPKARAK FEAAWNVKGL PDKPGLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE ISVLAPALGG IKYRRIEKDG LQWPAPTEEH PGTPTLHRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG IQVGDKVRVK SRRGEVVVTA NPTDRVPKGM VWMAFHFRDG CANWLTNPVF DPVTQTAEYK ACAVKIEKA HMM: 223-311 GLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTV ALI: 3-91 SFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNC ENV: 1-94 TNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQGACDMG ALPNVFPGYQ QVADPKARAK FEAAWNVKGL PDKPGLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE ISVLAPALGG IKYRRIEKDG LQWPAPTEEH PGTPTLHRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG IQVGDKVRVK SRRGEVVVTA NPTDRVPKGM VWMAFHFRDG CANWLTNPVF DPVTQTAEYK ACAVKIEKA HMM: 385-431 HRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQ ALI: 94-139 GFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY T ENV: 91-188 CCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQGACDMG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQGACDMG ALPNVFPGYQ QVADPKARAK FEAAWNVKGL PDKPGLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE ISVLAPALGG IKYRRIEKDG LQWPAPTEEH PGTPTLHRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG IQVGDKVRVK SRRGEVVVTA NPTDRVPKGM VWMAFHFRDG CANWLTNPVF DPVTQTAEYK ACAVKIEKA HMM: 610-688 ALI: 261-337 CLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWA ENV: 249-354 ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE ISVLAP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQGACDMG ALPNVFPGYQ QVADPKARAK FEAAWNVKGL PDKPGLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE ISVLAPALGG IKYRRIEKDG LQWPAPTEEH PGTPTLHRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG IQVGDKVRVK SRRGEVVVTA NPTDRVPKGM VWMAFHFRDG CANWLTNPVF DPVTQTAEYK ACAVKIEKA HMM: 244-327 FGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKE ALI: 8-91 A RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNC ENV: 1-95 TNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQGACDMG ALPNVFPGYQ QVADPKARAK FEAAWNVKGL PDKPGLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE ISVLAPALGG IKYRRIEKDG LQWPAPTEEH PGTPTLHRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG IQVGDKVRVK SRRGEVVVTA NPTDRVPKGM VWMAFHFRDG CANWLTNPVF DPVTQTAEYK ACAVKIEKA HMM: 401-459 DWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG I ALI: 95-151 FDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNN ENV: 91-182 CCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQGACDMG ALPNVFPGYQ QVADPKARAK FEAAWNVKGL PDKPGLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE ISVLAPALGG IKYRRIEKDG LQWPAPTEEH PGTPTLHRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG IQVGDKVRVK SRRGEVVVTA NPTDRVPKGM VWMAFHFRDG CANWLTNPVF DPVTQTAEYK ACAVKIEKA HMM: 644-711 ALI: 280-345 RFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELW ENV: 267-350 FL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE IS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQGACDMG ALPNVFPGYQ QVADPKARAK FEAAWNVKGL PDKPGLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE ISVLAPALGG IKYRRIEKDG LQWPAPTEEH PGTPTLHRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG IQVGDKVRVK SRRGEVVVTA NPTDRVPKGM VWMAFHFRDG CANWLTNPVF DPVTQTAEYK ACAVKIEKA HMM: 223-308 GLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV ALI: 6-91 DFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNC ENV: 2-96 NSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGFD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQGACDMG ALPNVFPGYQ QVADPKARAK FEAAWNVKGL PDKPGLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE ISVLAPALGG IKYRRIEKDG LQWPAPTEEH PGTPTLHRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG IQVGDKVRVK SRRGEVVVTA NPTDRVPKGM VWMAFHFRDG CANWLTNPVF DPVTQTAEYK ACAVKIEKA HMM: 384-461 LHRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG IQV ALI: 95-172 FDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGV ENV: 75-180 HVLI TEDLYDKEYV KNCCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGDFA RAKLILAIGT NMTEAHPVAS SFVKNAVQNG GELIVVDPRR TGLADHASQH LQLRVGSDIA LLNGLMHVLI TEDLYDKEYV KNCCTGFDEL KKKVMEYPPE RAAEISGVDA ETIRQVARKL ATVRPAMLAY TLGITEHTCG MNNVLSCANL QMLLGNVGFE CGGVNPLRGQ NNVQGACDMG ALPNVFPGYQ QVADPKARAK FEAAWNVKGL PDKPGLMMPQ MMDGLASGKV KAFYIFGENL ANTEPDIRHV EHCLDSAEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQELWDNE ISVLAPALGG IKYRRIEKDG LQWPAPTEEH PGTPTLHRDG KFTCGLGNLV PVDWTPPAEV PDKEYPFVLS TGRRLFHYHT RTQTGRCEGL NDLLGEETAD MSREDGIAMG IQVGDKVRVK SRRGEVVVTA NPTDRVPKGM VWMAFHFRDG CANWLTNPVF DPVTQTAEYK ACAVKIEKA HMM: 621-679 ALI: 275-331 PTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARR ENV: 265-342 AEFL VCNDIFPTET TRFADVVFPV AAWSENDGTF SNSERRVSRV RTVSEPPGVA KPNWWVFKEI ARRMGQEWAS SSAQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
PF04879: 51-104 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF00384: 107-509 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
PF01568: 697-790 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 110-158 QPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR ALI: 92-141 CALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLG ENV: 73-154 KRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 259-311 AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKN ALI: 245-297 AKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADR ENV: 239-300 QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 396-428 VPL GALPELPGDP SALKGLKQLR LDLASSQKGP ALI: 323-356 AYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAV ENV: 312-389 HKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 605-684 DGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSA ALI: 470-551 KLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLG ENV: 455-573 MLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 869-915 ALI: 710-756 QFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYL ENV: 704-770 ILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 127-173 IA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAA ALI: 93-140 ALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KL ENV: 80-151 GNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 276-327 ALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPE ALI: 246-297 KIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADR ENV: 239-299 QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV F Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 411-473 LKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQ ALI: 323-386 AYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKA ENV: 313-394 KGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 602-702 NYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFD ALI: 454-554 VMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSI ENV: 440-571 FLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 868-930 ALI: 706-766 RQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYD ENV: 655-771 QVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 97-153 AG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLA ALI: 82-139 PNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK K ENV: 72-149 GKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK P Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 256-309 TTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ G ALI: 245-298 AKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV ENV: 226-302 SPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 393-458 APEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH ALI: 323-388 AYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG ENV: 309-401 GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GAL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKVGRRAVL QFMAGAVGGT LLSPLPWKLT DDAAIWSQNW FWRPSPARGE ITRKPTVCAL CEGGCGVQAR LVDGKRAILL EGNPNHPVNQ GGICALGAAG LQFLYAPYRI AQPLKQTKRR GDPTGFQPIA WNEAVGELAK KLGQMRADGK PNGLAGITRR RCSSMDALLN QFFAAYGSPN LFKMPAHADS LKLAGAVTTG REAPFGCNIE DAPYILSFGA GLVEGWGSPG RMQAAFRRWR QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LAAQLLLAKG QTGDDDQVYL PHFSQVPPRG SDKDYPLLLV TYQMSALADR DLANPPFMTK TVFDFILRQN DQFVEINPAT ASELGMAEGD SAVLKTPQGE VPVRVHLYAG ARPKVVYLAQ GLGHKAYDEY IKDKGVNANG VVEVQLDRVT GLGTVWAARA HLRRA HMM: 239-640 QGGKSAAKIV QVDSRCSTTA AMADRWIAVP PGTEAALALG IAHLMVKDKL YDAEFMADRV FGFEDWTDSQ GKNHKGFKFL VQTDAYTPEA ISKLTGVDPA KIRELAKEFG TQKGAVAVWG QPQGSVPKDM YNELSFLALN ALKGNIKAGG AIGLAPEVPL GALPELPGDP SALKGLKQLR LDLASSQKGP PPVLPGNNLH GFLDAVSNGG KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLGGSIAAAL PWASHEEYLK KRAEGLAASA RGALADKKGV ELWKLQPEEA VKPNYKDGAD LWKKLAGGAC WYDAPVDPLK DLKTESGKFE LA ALI: 464-508 YGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG ENV: 449-551 KYPIEVMLVH EANPAYGLCE NKLFQQALTK IGTLVSLSSY MDETAQQADL ILPIHTAFEG FDDVIGIPGA PYAYYGVCAP VLKPHLNTKA AGDIVMSVAK QLG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MTNSFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTENSDAL IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NNVQGACDMG ALPNVYPGYQ AVTVPEVRQK FETAWKRNLP PNAGLTIMEM LQGCSDGKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEYPMHYES SEELFNEMAA LNPSFGGISY ARLEREELCW PCLSPDHPGT PILHIGKFSR GRGLFHAIEY KPPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP LHYEEAAANL LTNPALDPIS KTPEYKVCAV KLEKVAQGVT V
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
PF00384: 1-328 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF01568: 411-518 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MTNSFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTENSDAL IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NNVQGACDMG ALPNVYPGYQ AVTVPEVRQK FETAWKRNLP PNAGLTIMEM LQGCSDGKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEYPMHYES SEELFNEMAA LNPSFGGISY ARLEREELCW PCLSPDHPGT PILHIGKFSR GRGLFHAIEY KPPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP LHYEEAAANL LTNPALDPIS KTPEYKVCAV KLEKVAQGVT V HMM: 251-314 DPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPI ALI: 31-94 LLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTEN ENV: 1-100 TNSFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTENSDAL IE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTENSDAL IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NNVQGACDMG ALPNVYPGYQ AVTVPEVRQK FETAWKRNLP PNAGLTIMEM LQGCSDGKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEYPMHYES SEELFNEMAA LNPSFGGISY ARLEREELCW PCLSPDHPGT PILHIGKFSR GRGLFHAIEY KPPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP LHYEEAAANL LTNPALDPIS KTPEYKVCAV KLEKVAQGVT V HMM: 389-469 GRGLFHAIEY KPPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG T ALI: 98-180 L IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NN ENV: 94-189 NSDAL IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NNVQGACDMG A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTENSDAL IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NNVQGACDMG ALPNVYPGYQ AVTVPEVRQK FETAWKRNLP PNAGLTIMEM LQGCSDGKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEYPMHYES SEELFNEMAA LNPSFGGISY ARLEREELCW PCLSPDHPGT PILHIGKFSR GRGLFHAIEY KPPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP LHYEEAAANL LTNPALDPIS KTPEYKVCAV KLEKVAQGVT V HMM: 608-685 ALI: 258-332 K HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEY ENV: 235-352 GKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEYPMHYES SEELFNEMAA LNPS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTENSDAL IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NNVQGACDMG ALPNVYPGYQ AVTVPEVRQK FETAWKRNLP PNAGLTIMEM LQGCSDGKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEYPMHYES SEELFNEMAA LNPSFGGISY ARLEREELCW PCLSPDHPGT PILHIGKFSR GRGLFHAIEY KPPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP LHYEEAAANL LTNPALDPIS KTPEYKVCAV KLEKVAQGVT V HMM: 839-916 ALI: 410-488 PFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP ENV: 399-496 KPPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP LHYEEAAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTENSDAL IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NNVQGACDMG ALPNVYPGYQ AVTVPEVRQK FETAWKRNLP PNAGLTIMEM LQGCSDGKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEYPMHYES SEELFNEMAA LNPSFGGISY ARLEREELCW PCLSPDHPGT PILHIGKFSR GRGLFHAIEY KPPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP LHYEEAAANL LTNPALDPIS KTPEYKVCAV KLEKVAQGVT V HMM: 239-330 AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LL ALI: 3-94 SFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTEN ENV: 1-98 TNSFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTENSDAL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTENSDAL IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NNVQGACDMG ALPNVYPGYQ AVTVPEVRQK FETAWKRNLP PNAGLTIMEM LQGCSDGKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEYPMHYES SEELFNEMAA LNPSFGGISY ARLEREELCW PCLSPDHPGT PILHIGKFSR GRGLFHAIEY KPPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP LHYEEAAANL LTNPALDPIS KTPEYKVCAV KLEKVAQGVT V HMM: 409-481 YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVK ALI: 103-175 EKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPL ENV: 94-188 NSDAL IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NNVQGACDMG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTENSDAL IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NNVQGACDMG ALPNVYPGYQ AVTVPEVRQK FETAWKRNLP PNAGLTIMEM LQGCSDGKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEYPMHYES SEELFNEMAA LNPSFGGISY ARLEREELCW PCLSPDHPGT PILHIGKFSR GRGLFHAIEY KPPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP LHYEEAAANL LTNPALDPIS KTPEYKVCAV KLEKVAQGVT V HMM: 595-695 ALI: 232-327 CSDGKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELS ENV: 198-333 Q AVTVPEVRQK FETAWKRNLP PNAGLTIMEM LQGCSDGKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEYP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSFDELE NANCLFVIGS NTTVAHPIVA GRLLKAKAKG NTLIVADPRK SHVAGLANIH IQHKLGSDVA LINGMMHVIY KNGWHNRAFI EERTENSDAL IEMIEKYPPE RVAEITGVPA SAIIEVAECY AKSEASSIVY CLGITQHTTA VDNVKSLANL SMLCGQIGRP STGVNPLRGQ NNVQGACDMG ALPNVYPGYQ AVTVPEVRQK FETAWKRNLP PNAGLTIMEM LQGCSDGKIK AMVILGENPV MSDPDSNHVK HALESVEFFM AIDIFPTPTT ALAHVVLPAA SFAEVDGTFS NSERRVQRVR KAIEPIAGKT NWQIIQELST LLEYPMHYES SEELFNEMAA LNPSFGGISY ARLEREELCW PCLSPDHPGT PILHIGKFSR GRGLFHAIEY KPPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP LHYEEAAANL LTNPALDPIS KTPEYKVCAV KLEKVAQGVT V HMM: 841-917 ALI: 409-486 YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVF ENV: 400-494 PPAETPDEE YPFWLTTGTG YAHYLTATMT RRCKHLDREM PELITDLNPE DGIRMRIANG EYVRVSSRRG TLITRVQLTQ RVKPGMVFMP LHYEEA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MGVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFKD GLFSGYDPAA RKYDKSTWVF RLDANGVPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLKT PAASLTTLDE YLARNTPKTR EPQSANWYQN TPKYMVSLLK SWYGDKAIKE NGFAYSYLPK IDDGQDATLL DMIDKMYAGK IKGFTCVGQN PACSNPNAGK TRKALANLDW MVHINIFDNE TASFWKGPGM DPKKIKTEVF LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGDKS FKKGECVPGF SYLQADGKTS CGIWIHCGSF TQDGTNLIAR RKKDDPTGLG LYPEWAWAWP MNRRILYNRA SVDEKGQPWD PRRAVLKWAD GKWVGDVPDG PWPPLSDKEK GKLPFIMKPD GVASLFGPGL ADGPFPEHYE PLESPLSKSL ISAQLSSPVI RIFNSDCDKI AGCDPRFPLV CTTYSCTEHW CTGADTRWQS WLTETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP LKVGGQTLHQ VGITYNYGWL FPKDCGDSAN LLTPTAGDPN TGTPEYRAFM VNVTKV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
PF04879: 47-99 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
PF00384: 106-652 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF01568: 888-1008 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MGVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFKD GLFSGYDPAA RKYDKSTWVF RLDANGVPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLKT PAASLTTLDE YLARNTPKTR EPQSANWYQN TPKYMVSLLK SWYGDKAIKE NGFAYSYLPK IDDGQDATLL DMIDKMYAGK IKGFTCVGQN PACSNPNAGK TRKALANLDW MVHINIFDNE TASFWKGPGM DPKKIKTEVF LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGDKS FKKGECVPGF SYLQADGKTS CGIWIHCGSF TQDGTNLIAR RKKDDPTGLG LYPEWAWAWP MNRRILYNRA SVDEKGQPWD PRRAVLKWAD GKWVGDVPDG PWPPLSDKEK GKLPFIMKPD GVASLFGPGL ADGPFPEHYE PLESPLSKSL ISAQLSSPVI RIFNSDCDKI AGCDPRFPLV CTTYSCTEHW CTGADTRWQS WLTETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP LKVGGQTLHQ VGITYNYGWL FPKDCGDSAN LLTPTAGDPN TGTPEYRAFM VNVTKV HMM: 6-315 EFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFS ALI: 3-307 TRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNAS ENV: 1-314 GVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
Sequence: MGVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFKD GLFSGYDPAA RKYDKSTWVF RLDANGVPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLKT PAASLTTLDE YLARNTPKTR EPQSANWYQN TPKYMVSLLK SWYGDKAIKE NGFAYSYLPK IDDGQDATLL DMIDKMYAGK IKGFTCVGQN PACSNPNAGK TRKALANLDW MVHINIFDNE TASFWKGPGM DPKKIKTEVF LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGDKS FKKGECVPGF SYLQADGKTS CGIWIHCGSF TQDGTNLIAR RKKDDPTGLG LYPEWAWAWP MNRRILYNRA SVDEKGQPWD PRRAVLKWAD GKWVGDVPDG PWPPLSDKEK GKLPFIMKPD GVASLFGPGL ADGPFPEHYE PLESPLSKSL ISAQLSSPVI RIFNSDCDKI AGCDPRFPLV CTTYSCTEHW CTGADTRWQS WLTETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP LKVGGQTLHQ VGITYNYGWL FPKDCGDSAN LLTPTAGDPN TGTPEYRAFM VNVTKV HMM: 384-467 DLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLK ALI: 357-443 CV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNAL ENV: 346-462 PEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHIL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
Sequence: MGVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFKD GLFSGYDPAA RKYDKSTWVF RLDANGVPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLKT PAASLTTLDE YLARNTPKTR EPQSANWYQN TPKYMVSLLK SWYGDKAIKE NGFAYSYLPK IDDGQDATLL DMIDKMYAGK IKGFTCVGQN PACSNPNAGK TRKALANLDW MVHINIFDNE TASFWKGPGM DPKKIKTEVF LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGDKS FKKGECVPGF SYLQADGKTS CGIWIHCGSF TQDGTNLIAR RKKDDPTGLG LYPEWAWAWP MNRRILYNRA SVDEKGQPWD PRRAVLKWAD GKWVGDVPDG PWPPLSDKEK GKLPFIMKPD GVASLFGPGL ADGPFPEHYE PLESPLSKSL ISAQLSSPVI RIFNSDCDKI AGCDPRFPLV CTTYSCTEHW CTGADTRWQS WLTETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP LKVGGQTLHQ VGITYNYGWL FPKDCGDSAN LLTPTAGDPN TGTPEYRAFM VNVTKV HMM: 634-707 TAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGDK ALI: 609-680 LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY AD ENV: 599-706 DPKKIKTEVF LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
Sequence: MGVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFKD GLFSGYDPAA RKYDKSTWVF RLDANGVPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLKT PAASLTTLDE YLARNTPKTR EPQSANWYQN TPKYMVSLLK SWYGDKAIKE NGFAYSYLPK IDDGQDATLL DMIDKMYAGK IKGFTCVGQN PACSNPNAGK TRKALANLDW MVHINIFDNE TASFWKGPGM DPKKIKTEVF LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGDKS FKKGECVPGF SYLQADGKTS CGIWIHCGSF TQDGTNLIAR RKKDDPTGLG LYPEWAWAWP MNRRILYNRA SVDEKGQPWD PRRAVLKWAD GKWVGDVPDG PWPPLSDKEK GKLPFIMKPD GVASLFGPGL ADGPFPEHYE PLESPLSKSL ISAQLSSPVI RIFNSDCDKI AGCDPRFPLV CTTYSCTEHW CTGADTRWQS WLTETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP LKVGGQTLHQ VGITYNYGWL FPKDCGDSAN LLTPTAGDPN TGTPEYRAFM VNVTKV HMM: 20-45 LSSLGVDML PVVAYAEGLS KIDKVKS ALI: 3-28 TRREFL FISGAMGAGL ALSSLGVDML ENV: 1-53 GVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
Sequence: MGVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFKD GLFSGYDPAA RKYDKSTWVF RLDANGVPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLKT PAASLTTLDE YLARNTPKTR EPQSANWYQN TPKYMVSLLK SWYGDKAIKE NGFAYSYLPK IDDGQDATLL DMIDKMYAGK IKGFTCVGQN PACSNPNAGK TRKALANLDW MVHINIFDNE TASFWKGPGM DPKKIKTEVF LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGDKS FKKGECVPGF SYLQADGKTS CGIWIHCGSF TQDGTNLIAR RKKDDPTGLG LYPEWAWAWP MNRRILYNRA SVDEKGQPWD PRRAVLKWAD GKWVGDVPDG PWPPLSDKEK GKLPFIMKPD GVASLFGPGL ADGPFPEHYE PLESPLSKSL ISAQLSSPVI RIFNSDCDKI AGCDPRFPLV CTTYSCTEHW CTGADTRWQS WLTETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP LKVGGQTLHQ VGITYNYGWL FPKDCGDSAN LLTPTAGDPN TGTPEYRAFM VNVTKV HMM: 127-330 WA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFKD GLFSGYDPAA RK ALI: 91-306 AKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNA ENV: 76-317 IEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
Sequence: MGVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFKD GLFSGYDPAA RKYDKSTWVF RLDANGVPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLKT PAASLTTLDE YLARNTPKTR EPQSANWYQN TPKYMVSLLK SWYGDKAIKE NGFAYSYLPK IDDGQDATLL DMIDKMYAGK IKGFTCVGQN PACSNPNAGK TRKALANLDW MVHINIFDNE TASFWKGPGM DPKKIKTEVF LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGDKS FKKGECVPGF SYLQADGKTS CGIWIHCGSF TQDGTNLIAR RKKDDPTGLG LYPEWAWAWP MNRRILYNRA SVDEKGQPWD PRRAVLKWAD GKWVGDVPDG PWPPLSDKEK GKLPFIMKPD GVASLFGPGL ADGPFPEHYE PLESPLSKSL ISAQLSSPVI RIFNSDCDKI AGCDPRFPLV CTTYSCTEHW CTGADTRWQS WLTETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP LKVGGQTLHQ VGITYNYGWL FPKDCGDSAN LLTPTAGDPN TGTPEYRAFM VNVTKV HMM: 399-481 DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLKT PAASLTTLDE YLA ALI: 357-443 CV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNAL ENV: 345-458 VPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
Sequence: MGVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFKD GLFSGYDPAA RKYDKSTWVF RLDANGVPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLKT PAASLTTLDE YLARNTPKTR EPQSANWYQN TPKYMVSLLK SWYGDKAIKE NGFAYSYLPK IDDGQDATLL DMIDKMYAGK IKGFTCVGQN PACSNPNAGK TRKALANLDW MVHINIFDNE TASFWKGPGM DPKKIKTEVF LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGDKS FKKGECVPGF SYLQADGKTS CGIWIHCGSF TQDGTNLIAR RKKDDPTGLG LYPEWAWAWP MNRRILYNRA SVDEKGQPWD PRRAVLKWAD GKWVGDVPDG PWPPLSDKEK GKLPFIMKPD GVASLFGPGL ADGPFPEHYE PLESPLSKSL ISAQLSSPVI RIFNSDCDKI AGCDPRFPLV CTTYSCTEHW CTGADTRWQS WLTETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP LKVGGQTLHQ VGITYNYGWL FPKDCGDSAN LLTPTAGDPN TGTPEYRAFM VNVTKV HMM: 106-311 RLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SID ALI: 89-306 LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNA ENV: 41-314 DKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
Sequence: MGVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFKD GLFSGYDPAA RKYDKSTWVF RLDANGVPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLKT PAASLTTLDE YLARNTPKTR EPQSANWYQN TPKYMVSLLK SWYGDKAIKE NGFAYSYLPK IDDGQDATLL DMIDKMYAGK IKGFTCVGQN PACSNPNAGK TRKALANLDW MVHINIFDNE TASFWKGPGM DPKKIKTEVF LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGDKS FKKGECVPGF SYLQADGKTS CGIWIHCGSF TQDGTNLIAR RKKDDPTGLG LYPEWAWAWP MNRRILYNRA SVDEKGQPWD PRRAVLKWAD GKWVGDVPDG PWPPLSDKEK GKLPFIMKPD GVASLFGPGL ADGPFPEHYE PLESPLSKSL ISAQLSSPVI RIFNSDCDKI AGCDPRFPLV CTTYSCTEHW CTGADTRWQS WLTETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP LKVGGQTLHQ VGITYNYGWL FPKDCGDSAN LLTPTAGDPN TGTPEYRAFM VNVTKV HMM: 379-464 GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPG ALI: 354-443 NPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNAL ENV: 344-450 GVPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
Sequence: MGVTRREFL FISGAMGAGL ALSSLGVDML PVVAYAEGLS KIDKVKSAKE MYSLCYHCAV TCGLICSTDT KTGKIINIEG DPDNPINEGS LCAKGAASLQ MSARNENRLT RVLYRKPGGN QWEVKTWDWA LTRIAKNIKA VRDKEFIVKN AKGQVVNRVE ALAHMGSSKL DNEECWMITT AMRALGLVYL DHQARVCHAP SVASLAESLG RGSMTNHPID IGNSDCVLVM GGNAAEAHPI TFRWAVRAKD KGAKIIHVDP RFTRTSAIAD HHAFLRAGTD IAFLGGMIKY ILDNNKYFEE YVRNYTNASC SIDEKFSFKD GLFSGYDPAA RKYDKSTWVF RLDANGVPEK DPTLKNPRCV LQMMKAHYAR YDLEKVSSIT GTPVEDLKTI YELYSSTGVR DKAGTILYAL GWTQHTVGVQ NIRTMTIVQL LLGNIGIAGG GVNALRGQPN VQGSTDQAIL AHILPGYLKT PAASLTTLDE YLARNTPKTR EPQSANWYQN TPKYMVSLLK SWYGDKAIKE NGFAYSYLPK IDDGQDATLL DMIDKMYAGK IKGFTCVGQN PACSNPNAGK TRKALANLDW MVHINIFDNE TASFWKGPGM DPKKIKTEVF LLPAAAQMEK AGSMTNTGRW LQWKYTAEKP PGDALSMGDI LYRLVMKLKD LYKKEKGTFP DPILDLQWNY ADVKGMYDST AVAKAMNGYF LDDVTVGDKS FKKGECVPGF SYLQADGKTS CGIWIHCGSF TQDGTNLIAR RKKDDPTGLG LYPEWAWAWP MNRRILYNRA SVDEKGQPWD PRRAVLKWAD GKWVGDVPDG PWPPLSDKEK GKLPFIMKPD GVASLFGPGL ADGPFPEHYE PLESPLSKSL ISAQLSSPVI RIFNSDCDKI AGCDPRFPLV CTTYSCTEHW CTGADTRWQS WLTETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP LKVGGQTLHQ VGITYNYGWL FPKDCGDSAN LLTPTAGDPN TGTPEYRAFM VNVTKV HMM: 847-894 YE PLESPLSKSL ISAQLSSPVI RIFNSDCDKI AGCDPRFPLV CTTYSC ALI: 912-959 ETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP L ENV: 878-978 I AGCDPRFPLV CTTYSCTEHW CTGADTRWQS WLTETMPQAY VEISREFADL RGIENGEKVK VESVRGKVEC VAMVTTRLRP LKVGGQTLHQ VGITYNYGWL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
PF13510: 14-85 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
PF10588: 91-131 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
PF13187: 153-212 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF04879: 226-281 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF00384: 283-707 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF01568: 791-898 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 402-443 VAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDI ALI: 472-512 ESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALL ENV: 470-557 GFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 644-704 LICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEI ALI: 656-714 RFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKS ENV: 633-726 HVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEIS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 873-927 EACANW LTNPVFDPVT QTAEYKACAV KVEKIV ALI: 822-872 TADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFR ENV: 782-886 KEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 127-330 DH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS AR ALI: 269-470 VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DG ENV: 263-471 NHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 97-314 LL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKI ALI: 256-470 GVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DG ENV: 220-471 KGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 386-430 AKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DH ALI: 471-514 FESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVY ENV: 468-564 T DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 615-691 KAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAP ALI: 642-716 EFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSES ENV: 630-730 DIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 868-916 A FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV ALI: 820-868 EETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA ENV: 783-879 EVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW L Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 105-311 NCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRL ALI: 266-470 RLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DG ENV: 195-472 SSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 385-459 NAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL H ALI: 472-546 ESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACG ENV: 469-554 DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 619-674 IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTF ALI: 649-702 NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFK ENV: 639-717 SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MGEDIINLT VNGKNFQGRN IRGKRGQTVL EVLKDNGIHV PTLCYHPRMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSEFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDIAAR GSDSYITTFN NTSLAESSCV SCGQCVQACP VGALTEKKSR FKGRAWEMKK VRTTCPYCGV GCQMWLHVKG GRIVKVTGVE EGAPNHGRLC VKGRFGYDFI YSEDRLKTPL IKSNDGFREA SWDEALDLVA SRLKKIIAKH GPDSVAGVSS ARSINEDSYQ MQKLFRTAIG TNNIDNCARV CHAPTVAGLA KSFGSGAMTN SFDDFANAKM ILAIGTNATE AHPVAGTYLK NAVAKGAELI VVDPRRIELA DHAVLHAQIK VGSDIAFLNG VMNVLINENL HDKQYVASYT DGFESLKAKV MEYPPEKAAG ICGVSAEMIR DVARRLASVK PALLVYTLGI TEHTCGMNNV LSCANLQMLL GNVGFACGGV NPIRGQNNVQ GACDMGALPN LFPGYQRVDD PKAQEKFKAA WNVASLPDRP GIMLPQMLDG LADGKIKAFY IFGENLANSE PDIKHVEHCL SSAEFLICQD NFPNETTRFA DVILPAAAWS ENDGTFASSE RRISRVRTAS EAPGISRPNW WIFKEIARRM GQDWKSESGQ ELWDDEISVL SPPFAGIKYS RIEGDGLQWP VPTETHPGTP VMHKDGKFTG GRGQFVAVDW TPPKEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV KVEKIV HMM: 857-899 TD RMQKGNVWMA FHFREACANW LTNPVFDPVT QTAEYKACAV K ALI: 826-868 SRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA ENV: 782-890 KEVPDAE YPFTFCTGRR LYHYHTRTQT GRCQGLNELL GEETADISRL DAAELGIEDG EYIRVRSRRG EVKVKARVTD RMQKGNVWMA FHFREACANW LTNPVFDPVT QT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900
Sequence: MTNHYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG LFSGYDPAAR KYDKSTWAIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL DDGQDATVLN MIDKMYEGKI KGFTCIGQDP AVSLPNANKV RQAFTKLDWM VHVNIFDNET ASFWKGPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVWNYG DAKGHYDALA TSKAVNGLFL EDVTIGDKTF KKGQCVPGFG NLQADGKTSC GNWIYSGAFA ADGTNLMARR KKDDPTGLGL YPEWGWAWPV NRRILYNRAS VDKNGQPFDP SRPLLKWVDG KWVGDVPDGP WPPLSDKEKG KLPFIMKPDG VASLFGPGLA DGPFPEHYEP LEGPLAKNPM SSQLNNPAIK IFTKECDLYS GCDPKFPFVC TTYSCTEHWC TGAETRWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGGQTIHQV GMTFNYGWLF PKDCGDTANL LTPTAGDANT MTPEYKAFMV NVTKV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
PF00384: 1-442 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF01568: 677-797 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
Sequence: MTNHYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG LFSGYDPAAR KYDKSTWAIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL DDGQDATVLN MIDKMYEGKI KGFTCIGQDP AVSLPNANKV RQAFTKLDWM VHVNIFDNET ASFWKGPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVWNYG DAKGHYDALA TSKAVNGLFL EDVTIGDKTF KKGQCVPGFG NLQADGKTSC GNWIYSGAFA ADGTNLMARR KKDDPTGLGL YPEWGWAWPV NRRILYNRAS VDKNGQPFDP SRPLLKWVDG KWVGDVPDGP WPPLSDKEKG KLPFIMKPDG VASLFGPGLA DGPFPEHYEP LEGPLAKNPM SSQLNNPAIK IFTKECDLYS GCDPKFPFVC TTYSCTEHWC TGAETRWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGGQTIHQV GMTFNYGWLF PKDCGDTANL LTPTAGDANT MTPEYKAFMV NVTKV HMM: 230-319 NALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL D ALI: 10-100 ADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VD ENV: 3-106 HYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MTNHYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG LFSGYDPAAR KYDKSTWAIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL DDGQDATVLN MIDKMYEGKI KGFTCIGQDP AVSLPNANKV RQAFTKLDWM VHVNIFDNET ASFWKGPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVWNYG DAKGHYDALA TSKAVNGLFL EDVTIGDKTF KKGQCVPGFG NLQADGKTSC GNWIYSGAFA ADGTNLMARR KKDDPTGLGL YPEWGWAWPV NRRILYNRAS VDKNGQPFDP SRPLLKWVDG KWVGDVPDGP WPPLSDKEKG KLPFIMKPDG VASLFGPGLA DGPFPEHYEP LEGPLAKNPM SSQLNNPAIK IFTKECDLYS GCDPKFPFVC TTYSCTEHWC TGAETRWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGGQTIHQV GMTFNYGWLF PKDCGDTANL LTPTAGDANT MTPEYKAFMV NVTKV HMM: 384-468 GPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVWNYG ALI: 146-233 CVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALR ENV: 138-300 D PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MTNHYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG LFSGYDPAAR KYDKSTWAIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL DDGQDATVLN MIDKMYEGKI KGFTCIGQDP AVSLPNANKV RQAFTKLDWM VHVNIFDNET ASFWKGPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVWNYG DAKGHYDALA TSKAVNGLFL EDVTIGDKTF KKGQCVPGFG NLQADGKTSC GNWIYSGAFA ADGTNLMARR KKDDPTGLGL YPEWGWAWPV NRRILYNRAS VDKNGQPFDP SRPLLKWVDG KWVGDVPDGP WPPLSDKEKG KLPFIMKPDG VASLFGPGLA DGPFPEHYEP LEGPLAKNPM SSQLNNPAIK IFTKECDLYS GCDPKFPFVC TTYSCTEHWC TGAETRWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGGQTIHQV GMTFNYGWLF PKDCGDTANL LTPTAGDANT MTPEYKAFMV NVTKV HMM: 635-692 HYEP LEGPLAKNPM SSQLNNPAIK IFTKECDLYS GCDPKFPFVC TTYSCTEHWC TGAE ALI: 399-454 LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKG ENV: 393-457 KTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MTNHYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG LFSGYDPAAR KYDKSTWAIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL DDGQDATVLN MIDKMYEGKI KGFTCIGQDP AVSLPNANKV RQAFTKLDWM VHVNIFDNET ASFWKGPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVWNYG DAKGHYDALA TSKAVNGLFL EDVTIGDKTF KKGQCVPGFG NLQADGKTSC GNWIYSGAFA ADGTNLMARR KKDDPTGLGL YPEWGWAWPV NRRILYNRAS VDKNGQPFDP SRPLLKWVDG KWVGDVPDGP WPPLSDKEKG KLPFIMKPDG VASLFGPGLA DGPFPEHYEP LEGPLAKNPM SSQLNNPAIK IFTKECDLYS GCDPKFPFVC TTYSCTEHWC TGAETRWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGGQTIHQV GMTFNYGWLF PKDCGDTANL LTPTAGDANT MTPEYKAFMV NVTKV HMM: 874-914 ALI: 711-751 SRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVG ENV: 704-751 PEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MTNHYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG LFSGYDPAAR KYDKSTWAIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL DDGQDATVLN MIDKMYEGKI KGFTCIGQDP AVSLPNANKV RQAFTKLDWM VHVNIFDNET ASFWKGPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVWNYG DAKGHYDALA TSKAVNGLFL EDVTIGDKTF KKGQCVPGFG NLQADGKTSC GNWIYSGAFA ADGTNLMARR KKDDPTGLGL YPEWGWAWPV NRRILYNRAS VDKNGQPFDP SRPLLKWVDG KWVGDVPDGP WPPLSDKEKG KLPFIMKPDG VASLFGPGLA DGPFPEHYEP LEGPLAKNPM SSQLNNPAIK IFTKECDLYS GCDPKFPFVC TTYSCTEHWC TGAETRWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGGQTIHQV GMTFNYGWLF PKDCGDTANL LTPTAGDANT MTPEYKAFMV NVTKV HMM: 246-337 ILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL DDGQDATVLN MIDKMYEGK ALI: 10-102 ADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEK ENV: 6-284 DIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG LFSGYDPAAR KYDKSTWAIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MTNHYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG LFSGYDPAAR KYDKSTWAIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL DDGQDATVLN MIDKMYEGKI KGFTCIGQDP AVSLPNANKV RQAFTKLDWM VHVNIFDNET ASFWKGPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVWNYG DAKGHYDALA TSKAVNGLFL EDVTIGDKTF KKGQCVPGFG NLQADGKTSC GNWIYSGAFA ADGTNLMARR KKDDPTGLGL YPEWGWAWPV NRRILYNRAS VDKNGQPFDP SRPLLKWVDG KWVGDVPDGP WPPLSDKEKG KLPFIMKPDG VASLFGPGLA DGPFPEHYEP LEGPLAKNPM SSQLNNPAIK IFTKECDLYS GCDPKFPFVC TTYSCTEHWC TGAETRWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGGQTIHQV GMTFNYGWLF PKDCGDTANL LTPTAGDANT MTPEYKAFMV NVTKV HMM: 869-916 ALI: 701-750 EAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QV ENV: 694-752 RWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MTNHYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG LFSGYDPAAR KYDKSTWAIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL DDGQDATVLN MIDKMYEGKI KGFTCIGQDP AVSLPNANKV RQAFTKLDWM VHVNIFDNET ASFWKGPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVWNYG DAKGHYDALA TSKAVNGLFL EDVTIGDKTF KKGQCVPGFG NLQADGKTSC GNWIYSGAFA ADGTNLMARR KKDDPTGLGL YPEWGWAWPV NRRILYNRAS VDKNGQPFDP SRPLLKWVDG KWVGDVPDGP WPPLSDKEKG KLPFIMKPDG VASLFGPGLA DGPFPEHYEP LEGPLAKNPM SSQLNNPAIK IFTKECDLYS GCDPKFPFVC TTYSCTEHWC TGAETRWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGGQTIHQV GMTFNYGWLF PKDCGDTANL LTPTAGDANT MTPEYKAFMV NVTKV HMM: 227-317 GG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPK ALI: 10-101 ADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDE ENV: 3-108 HYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MTNHYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG LFSGYDPAAR KYDKSTWAIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL DDGQDATVLN MIDKMYEGKI KGFTCIGQDP AVSLPNANKV RQAFTKLDWM VHVNIFDNET ASFWKGPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVWNYG DAKGHYDALA TSKAVNGLFL EDVTIGDKTF KKGQCVPGFG NLQADGKTSC GNWIYSGAFA ADGTNLMARR KKDDPTGLGL YPEWGWAWPV NRRILYNRAS VDKNGQPFDP SRPLLKWVDG KWVGDVPDGP WPPLSDKEKG KLPFIMKPDG VASLFGPGLA DGPFPEHYEP LEGPLAKNPM SSQLNNPAIK IFTKECDLYS GCDPKFPFVC TTYSCTEHWC TGAETRWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGGQTIHQV GMTFNYGWLF PKDCGDTANL LTPTAGDANT MTPEYKAFMV NVTKV HMM: 371-465 VNIFDNET ASFWKGPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVW ALI: 135-233 PQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALR ENV: 126-243 AIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MTNHYIDIK NADVILIMGS NAAEMHPISF KWVLRAREER GAKIIHVDPR FTRTSALADH YIALRSGTDI AFLGGMIKYI LENKKYFEEY VRDYTNASFI VDEKFSFNDG LFSGYDPAAR KYDKSTWAIK VDEKGIPQKD PTFENPRCVL QMLKAHYSRY DIDKVSSITG TPVEDLKTVY ELYASTGVKD KAGTELYALG WTQHTVGVQN IRAMSIIQGL LGNMGIAGGG INALRGEPNV QGSTDHAILS HILPGYLKAP VASLTTLEEY LKKNTPKTSE PQSANWYQNT PKYMVSLLKA WYGDKAVKEN DFGYANVPKL DDGQDATVLN MIDKMYEGKI KGFTCIGQDP AVSLPNANKV RQAFTKLDWM VHVNIFDNET ASFWKGPGLD PKKVKTEVFL LPAAASMEKE GSMSNSGRML QWKYTAEKPP GDALSVGDIL YRLVNKLKDL YKKEKGAFPD PIVNLVWNYG DAKGHYDALA TSKAVNGLFL EDVTIGDKTF KKGQCVPGFG NLQADGKTSC GNWIYSGAFA ADGTNLMARR KKDDPTGLGL YPEWGWAWPV NRRILYNRAS VDKNGQPFDP SRPLLKWVDG KWVGDVPDGP WPPLSDKEKG KLPFIMKPDG VASLFGPGLA DGPFPEHYEP LEGPLAKNPM SSQLNNPAIK IFTKECDLYS GCDPKFPFVC TTYSCTEHWC TGAETRWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGGQTIHQV GMTFNYGWLF PKDCGDTANL LTPTAGDANT MTPEYKAFMV NVTKV HMM: 848-896 ALI: 702-750 AQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QV ENV: 681-776 YSCTEHWC TGAETRWQSW LTEAQPEAYV EISRELAELR GIKNGERVRV ESPRGKVECV AMVTTRFRPF QVGGQTIHQV GMTFNYGWLF PKDCGDTA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MAKKKVFSV CGMCSVRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TPGAVGRKGL KKLVDLFPKP GEKRADGVGW RHPQFDPGAG LLHLAFKAMQ AGDPYPLKAY IAYRHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC FETIEDLWNY QLQGTGVRIE DFAATGMVPL VDKPHYRELD ETALKTPSGR IELVSDRLEG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
PF04879: 3-55 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00384: 61-482 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF01568: 569-649 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
Sequence: MAKKKVFSV CGMCSVRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TPGAVGRKGL KKLVDLFPKP GEKRADGVGW RHPQFDPGAG LLHLAFKAMQ AGDPYPLKAY IAYRHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC FETIEDLWNY QLQGTGVRIE DFAATGMVPL VDKPHYRELD ETALKTPSGR IELVSDRLEG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA HMM: 127-325 NY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLP ALI: 45-241 ARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAG ENV: 30-251 IQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAKKKVFSV CGMCSVRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TPGAVGRKGL KKLVDLFPKP GEKRADGVGW RHPQFDPGAG LLHLAFKAMQ AGDPYPLKAY IAYRHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC FETIEDLWNY QLQGTGVRIE DFAATGMVPL VDKPHYRELD ETALKTPSGR IELVSDRLEG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA HMM: 406-476 KGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILG ALI: 252-323 AFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGG ENV: 244-330 IKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAKKKVFSV CGMCSVRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TPGAVGRKGL KKLVDLFPKP GEKRADGVGW RHPQFDPGAG LLHLAFKAMQ AGDPYPLKAY IAYRHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC FETIEDLWNY QLQGTGVRIE DFAATGMVPL VDKPHYRELD ETALKTPSGR IELVSDRLEG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA HMM: 625-700 GRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA ALI: 408-484 I FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGM ENV: 394-488 DPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAKKKVFSV CGMCSVRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TPGAVGRKGL KKLVDLFPKP GEKRADGVGW RHPQFDPGAG LLHLAFKAMQ AGDPYPLKAY IAYRHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC FETIEDLWNY QLQGTGVRIE DFAATGMVPL VDKPHYRELD ETALKTPSGR IELVSDRLEG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA HMM: 834-918 ALI: 559-642 PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFL ENV: 547-649 EG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH S Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAKKKVFSV CGMCSVRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TPGAVGRKGL KKLVDLFPKP GEKRADGVGW RHPQFDPGAG LLHLAFKAMQ AGDPYPLKAY IAYRHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC FETIEDLWNY QLQGTGVRIE DFAATGMVPL VDKPHYRELD ETALKTPSGR IELVSDRLEG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA HMM: 109-309 GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA Y ALI: 43-241 LCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAG ENV: 21-251 ESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAKKKVFSV CGMCSVRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TPGAVGRKGL KKLVDLFPKP GEKRADGVGW RHPQFDPGAG LLHLAFKAMQ AGDPYPLKAY IAYRHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC FETIEDLWNY QLQGTGVRIE DFAATGMVPL VDKPHYRELD ETALKTPSGR IELVSDRLEG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA HMM: 392-462 RHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAV ALI: 253-323 FVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGG ENV: 243-329 HIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN T Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAKKKVFSV CGMCSVRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TPGAVGRKGL KKLVDLFPKP GEKRADGVGW RHPQFDPGAG LLHLAFKAMQ AGDPYPLKAY IAYRHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC FETIEDLWNY QLQGTGVRIE DFAATGMVPL VDKPHYRELD ETALKTPSGR IELVSDRLEG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA HMM: 608-684 M NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQ ALI: 406-483 KGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLG ENV: 403-489 EALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC F Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAKKKVFSV CGMCSVRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TPGAVGRKGL KKLVDLFPKP GEKRADGVGW RHPQFDPGAG LLHLAFKAMQ AGDPYPLKAY IAYRHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC FETIEDLWNY QLQGTGVRIE DFAATGMVPL VDKPHYRELD ETALKTPSGR IELVSDRLEG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA HMM: 833-920 ALI: 561-647 KKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFG ENV: 547-658 EG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAKKKVFSV CGMCSVRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TPGAVGRKGL KKLVDLFPKP GEKRADGVGW RHPQFDPGAG LLHLAFKAMQ AGDPYPLKAY IAYRHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC FETIEDLWNY QLQGTGVRIE DFAATGMVPL VDKPHYRELD ETALKTPSGR IELVSDRLEG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA HMM: 87-306 VA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCR ALI: 24-241 DGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAG ENV: 14-268 VRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAKKKVFSV CGMCSVRCPI EVESEDGVCT FIQGNPHAAG IEKALCARGG AGIALIDDDE RPRHPLIRAG KRGEGKWRGV SWDEALDHVA GALKRIMESH GGRSILFSDR GGPFRDLHQA FVRGLGSPNY SNHDASCARN VEHAALSLFG LSRKDLVYDY RNAGHVVLQT RNLFESINVK EVNDLVAAIS HGCKLTVVDI RHTRTAAKAD RFFMIRPGTD YAFNLAVIHV LLRERLYDED FAGRHIKDLD RLEAFVRPYT PRWAEGETGI PAEEIASLAR SLAEAGPAVL WHPGWMTARY TDSFYVCRSA YIINALLGAI GAKGGLPLAN TPGAVGRKGL KKLVDLFPKP GEKRADGVGW RHPQFDPGAG LLHLAFKAMQ AGDPYPLKAY IAYRHDPLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMVPLC FETIEDLWNY QLQGTGVRIE DFAATGMVPL VDKPHYRELD ETALKTPSGR IELVSDRLEG AGLPSLKPYE PPKKAEKGKF RITFGRCPVH TQGHTMNNPL LHEQMPENVL WMNREAGENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG GGVAMQEHFV TVTKIA HMM: 605-679 GENM NLENGEEVEV SGSGYRGRIK VRLTDFIHPE AVFLVHGFGH SLPVETRAFG KGLSDSLFMR GGLEVWDEAG G ALI: 406-481 KGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKR ENV: 395-485 PLMG FPDPEALKGI FEKLDLLVSV TFSWSDTAWF SDVVLPLSPY LERESILACK NGLKPYFFVR QRAVEPRFDT RADWEILGGL AKRLGMV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MTNHWIDLA NADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV GEKFDFKDGL FSGYNAEKRS YDKSSWAYEL DEKGVPKKDL TLQNPRCVFQ LLAKHYSRYD LDTVSKVTGT PKDDLTKVYE AYSATGVPDK AGTIMYAMGW CQHSVGVQNI RTMSIIQLLL GNMGIAGGGV NALRGESNVQ GSTDQGLLFH ILPGYLPTPA ASLATLADYN KKNTPVSKDP LSANWWQNRP KYLVSLLKTL YGDAAKPENE FAYGWLPKID DGKAYSWLDL FDAMYKKEFT GFFSWGQNPA CSGANSNKTR QAMANLDWMV VVNLFENETA SFWKGPGMNP KKTKTEVFFL PCCAFLEKEG SIANSGRWAQ WRYKAQEPAG QSLPDGDIIY ELFLEIRKLY QKPGGKFPDP ILKLQWNYAA NHKFDPHLVA KEINGYWLKD TTVGDKTFKK GDLVPAFAML KDDGSTSCGN WIYCQSYNQD GNNMARRDKT DDSGIGLYPK WAWAWPVNRR IIYNRASVDP AGKPWNPKKA VIEFVGEVKD GKYTTQKWKG DVPDGPWYPL KNPDGSARED GKLAFIMKPD GYASIYGPGL ADGPFPEHYE PLECPVEKNL FSSRITNPVA AVFGTEKDII KSCDPKFPFV GTTYRVTEHW QTGVLTRWLP WLLEAEPQLF VEMSEELAKL KEIKNGDKVI VESPRGSVEA VAIVTKRWKP FQIQDQEVHQ VGLPWHFGWV WPPEGGDSAN LLTPSVGDPN TRIPESKAFM VNVRKKG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
PF00384: 1-441 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
PF01568: 690-808 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MTNHWIDLA NADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV GEKFDFKDGL FSGYNAEKRS YDKSSWAYEL DEKGVPKKDL TLQNPRCVFQ LLAKHYSRYD LDTVSKVTGT PKDDLTKVYE AYSATGVPDK AGTIMYAMGW CQHSVGVQNI RTMSIIQLLL GNMGIAGGGV NALRGESNVQ GSTDQGLLFH ILPGYLPTPA ASLATLADYN KKNTPVSKDP LSANWWQNRP KYLVSLLKTL YGDAAKPENE FAYGWLPKID DGKAYSWLDL FDAMYKKEFT GFFSWGQNPA CSGANSNKTR QAMANLDWMV VVNLFENETA SFWKGPGMNP KKTKTEVFFL PCCAFLEKEG SIANSGRWAQ WRYKAQEPAG QSLPDGDIIY ELFLEIRKLY QKPGGKFPDP ILKLQWNYAA NHKFDPHLVA KEINGYWLKD TTVGDKTFKK GDLVPAFAML KDDGSTSCGN WIYCQSYNQD GNNMARRDKT DDSGIGLYPK WAWAWPVNRR IIYNRASVDP AGKPWNPKKA VIEFVGEVKD GKYTTQKWKG DVPDGPWYPL KNPDGSARED GKLAFIMKPD GYASIYGPGL ADGPFPEHYE PLECPVEKNL FSSRITNPVA AVFGTEKDII KSCDPKFPFV GTTYRVTEHW QTGVLTRWLP WLLEAEPQLF VEMSEELAKL KEIKNGDKVI VESPRGSVEA VAIVTKRWKP FQIQDQEVHQ VGLPWHFGWV WPPEGGDSAN LLTPSVGDPN TRIPESKAFM VNVRKKG HMM: 230-319 ALRGESNVQ GSTDQGLLFH ILPGYLPTPA ASLATLADYN KKNTPVSKDP LSANWWQNRP KYLVSLLKTL YGDAAKPENE FAYGWLPKID D ALI: 10-99 ADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV G ENV: 3-109 HWIDLA NADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV GEKFDFKDGL F Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MTNHWIDLA NADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV GEKFDFKDGL FSGYNAEKRS YDKSSWAYEL DEKGVPKKDL TLQNPRCVFQ LLAKHYSRYD LDTVSKVTGT PKDDLTKVYE AYSATGVPDK AGTIMYAMGW CQHSVGVQNI RTMSIIQLLL GNMGIAGGGV NALRGESNVQ GSTDQGLLFH ILPGYLPTPA ASLATLADYN KKNTPVSKDP LSANWWQNRP KYLVSLLKTL YGDAAKPENE FAYGWLPKID DGKAYSWLDL FDAMYKKEFT GFFSWGQNPA CSGANSNKTR QAMANLDWMV VVNLFENETA SFWKGPGMNP KKTKTEVFFL PCCAFLEKEG SIANSGRWAQ WRYKAQEPAG QSLPDGDIIY ELFLEIRKLY QKPGGKFPDP ILKLQWNYAA NHKFDPHLVA KEINGYWLKD TTVGDKTFKK GDLVPAFAML KDDGSTSCGN WIYCQSYNQD GNNMARRDKT DDSGIGLYPK WAWAWPVNRR IIYNRASVDP AGKPWNPKKA VIEFVGEVKD GKYTTQKWKG DVPDGPWYPL KNPDGSARED GKLAFIMKPD GYASIYGPGL ADGPFPEHYE PLECPVEKNL FSSRITNPVA AVFGTEKDII KSCDPKFPFV GTTYRVTEHW QTGVLTRWLP WLLEAEPQLF VEMSEELAKL KEIKNGDKVI VESPRGSVEA VAIVTKRWKP FQIQDQEVHQ VGLPWHFGWV WPPEGGDSAN LLTPSVGDPN TRIPESKAFM VNVRKKG HMM: 384-468 PGMNP KKTKTEVFFL PCCAFLEKEG SIANSGRWAQ WRYKAQEPAG QSLPDGDIIY ELFLEIRKLY QKPGGKFPDP ILKLQWNYAA ALI: 145-232 CVFQ LLAKHYSRYD LDTVSKVTGT PKDDLTKVYE AYSATGVPDK AGTIMYAMGW CQHSVGVQNI RTMSIIQLLL GNMGIAGGGV NALR ENV: 134-245 PKKDL TLQNPRCVFQ LLAKHYSRYD LDTVSKVTGT PKDDLTKVYE AYSATGVPDK AGTIMYAMGW CQHSVGVQNI RTMSIIQLLL GNMGIAGGGV NALRGESNVQ GSTDQGL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MTNHWIDLA NADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV GEKFDFKDGL FSGYNAEKRS YDKSSWAYEL DEKGVPKKDL TLQNPRCVFQ LLAKHYSRYD LDTVSKVTGT PKDDLTKVYE AYSATGVPDK AGTIMYAMGW CQHSVGVQNI RTMSIIQLLL GNMGIAGGGV NALRGESNVQ GSTDQGLLFH ILPGYLPTPA ASLATLADYN KKNTPVSKDP LSANWWQNRP KYLVSLLKTL YGDAAKPENE FAYGWLPKID DGKAYSWLDL FDAMYKKEFT GFFSWGQNPA CSGANSNKTR QAMANLDWMV VVNLFENETA SFWKGPGMNP KKTKTEVFFL PCCAFLEKEG SIANSGRWAQ WRYKAQEPAG QSLPDGDIIY ELFLEIRKLY QKPGGKFPDP ILKLQWNYAA NHKFDPHLVA KEINGYWLKD TTVGDKTFKK GDLVPAFAML KDDGSTSCGN WIYCQSYNQD GNNMARRDKT DDSGIGLYPK WAWAWPVNRR IIYNRASVDP AGKPWNPKKA VIEFVGEVKD GKYTTQKWKG DVPDGPWYPL KNPDGSARED GKLAFIMKPD GYASIYGPGL ADGPFPEHYE PLECPVEKNL FSSRITNPVA AVFGTEKDII KSCDPKFPFV GTTYRVTEHW QTGVLTRWLP WLLEAEPQLF VEMSEELAKL KEIKNGDKVI VESPRGSVEA VAIVTKRWKP FQIQDQEVHQ VGLPWHFGWV WPPEGGDSAN LLTPSVGDPN TRIPESKAFM VNVRKKG HMM: 634-690 YGPGL ADGPFPEHYE PLECPVEKNL FSSRITNPVA AVFGTEKDII KSCDPKFPFV GT ALI: 397-451 FL PCCAFLEKEG SIANSGRWAQ WRYKAQEPAG QSLPDGDIIY ELFLEIRKLY QKP ENV: 389-459 KKTKTEVFFL PCCAFLEKEG SIANSGRWAQ WRYKAQEPAG QSLPDGDIIY ELFLEIRKLY QKPGGKFPDP I Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MTNHWIDLA NADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV GEKFDFKDGL FSGYNAEKRS YDKSSWAYEL DEKGVPKKDL TLQNPRCVFQ LLAKHYSRYD LDTVSKVTGT PKDDLTKVYE AYSATGVPDK AGTIMYAMGW CQHSVGVQNI RTMSIIQLLL GNMGIAGGGV NALRGESNVQ GSTDQGLLFH ILPGYLPTPA ASLATLADYN KKNTPVSKDP LSANWWQNRP KYLVSLLKTL YGDAAKPENE FAYGWLPKID DGKAYSWLDL FDAMYKKEFT GFFSWGQNPA CSGANSNKTR QAMANLDWMV VVNLFENETA SFWKGPGMNP KKTKTEVFFL PCCAFLEKEG SIANSGRWAQ WRYKAQEPAG QSLPDGDIIY ELFLEIRKLY QKPGGKFPDP ILKLQWNYAA NHKFDPHLVA KEINGYWLKD TTVGDKTFKK GDLVPAFAML KDDGSTSCGN WIYCQSYNQD GNNMARRDKT DDSGIGLYPK WAWAWPVNRR IIYNRASVDP AGKPWNPKKA VIEFVGEVKD GKYTTQKWKG DVPDGPWYPL KNPDGSARED GKLAFIMKPD GYASIYGPGL ADGPFPEHYE PLECPVEKNL FSSRITNPVA AVFGTEKDII KSCDPKFPFV GTTYRVTEHW QTGVLTRWLP WLLEAEPQLF VEMSEELAKL KEIKNGDKVI VESPRGSVEA VAIVTKRWKP FQIQDQEVHQ VGLPWHFGWV WPPEGGDSAN LLTPSVGDPN TRIPESKAFM VNVRKKG HMM: 244-335 GLLFH ILPGYLPTPA ASLATLADYN KKNTPVSKDP LSANWWQNRP KYLVSLLKTL YGDAAKPENE FAYGWLPKID DGKAYSWLDL FDAMYKK ALI: 8-99 A NADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV G ENV: 4-122 WIDLA NADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV GEKFDFKDGL FSGYNAEKRS YDKS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MTNHWIDLA NADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV GEKFDFKDGL FSGYNAEKRS YDKSSWAYEL DEKGVPKKDL TLQNPRCVFQ LLAKHYSRYD LDTVSKVTGT PKDDLTKVYE AYSATGVPDK AGTIMYAMGW CQHSVGVQNI RTMSIIQLLL GNMGIAGGGV NALRGESNVQ GSTDQGLLFH ILPGYLPTPA ASLATLADYN KKNTPVSKDP LSANWWQNRP KYLVSLLKTL YGDAAKPENE FAYGWLPKID DGKAYSWLDL FDAMYKKEFT GFFSWGQNPA CSGANSNKTR QAMANLDWMV VVNLFENETA SFWKGPGMNP KKTKTEVFFL PCCAFLEKEG SIANSGRWAQ WRYKAQEPAG QSLPDGDIIY ELFLEIRKLY QKPGGKFPDP ILKLQWNYAA NHKFDPHLVA KEINGYWLKD TTVGDKTFKK GDLVPAFAML KDDGSTSCGN WIYCQSYNQD GNNMARRDKT DDSGIGLYPK WAWAWPVNRR IIYNRASVDP AGKPWNPKKA VIEFVGEVKD GKYTTQKWKG DVPDGPWYPL KNPDGSARED GKLAFIMKPD GYASIYGPGL ADGPFPEHYE PLECPVEKNL FSSRITNPVA AVFGTEKDII KSCDPKFPFV GTTYRVTEHW QTGVLTRWLP WLLEAEPQLF VEMSEELAKL KEIKNGDKVI VESPRGSVEA VAIVTKRWKP FQIQDQEVHQ VGLPWHFGWV WPPEGGDSAN LLTPSVGDPN TRIPESKAFM VNVRKKG HMM: 227-316 GV NALRGESNVQ GSTDQGLLFH ILPGYLPTPA ASLATLADYN KKNTPVSKDP LSANWWQNRP KYLVSLLKTL YGDAAKPENE FAYGWLPK ALI: 10-99 ADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV G ENV: 4-107 WIDLA NADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV GEKFDFKDG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MTNHWIDLA NADCILIMGS NAAENHPISF RWVMKAKDKG AVVINVDPRF TKTSTKSDIY APLRSGTDIA FLGGMIKHIL ENKKFFNDYV INYTNASYIV GEKFDFKDGL FSGYNAEKRS YDKSSWAYEL DEKGVPKKDL TLQNPRCVFQ LLAKHYSRYD LDTVSKVTGT PKDDLTKVYE AYSATGVPDK AGTIMYAMGW CQHSVGVQNI RTMSIIQLLL GNMGIAGGGV NALRGESNVQ GSTDQGLLFH ILPGYLPTPA ASLATLADYN KKNTPVSKDP LSANWWQNRP KYLVSLLKTL YGDAAKPENE FAYGWLPKID DGKAYSWLDL FDAMYKKEFT GFFSWGQNPA CSGANSNKTR QAMANLDWMV VVNLFENETA SFWKGPGMNP KKTKTEVFFL PCCAFLEKEG SIANSGRWAQ WRYKAQEPAG QSLPDGDIIY ELFLEIRKLY QKPGGKFPDP ILKLQWNYAA NHKFDPHLVA KEINGYWLKD TTVGDKTFKK GDLVPAFAML KDDGSTSCGN WIYCQSYNQD GNNMARRDKT DDSGIGLYPK WAWAWPVNRR IIYNRASVDP AGKPWNPKKA VIEFVGEVKD GKYTTQKWKG DVPDGPWYPL KNPDGSARED GKLAFIMKPD GYASIYGPGL ADGPFPEHYE PLECPVEKNL FSSRITNPVA AVFGTEKDII KSCDPKFPFV GTTYRVTEHW QTGVLTRWLP WLLEAEPQLF VEMSEELAKL KEIKNGDKVI VESPRGSVEA VAIVTKRWKP FQIQDQEVHQ VGLPWHFGWV WPPEGGDSAN LLTPSVGDPN TRIPESKAFM VNVRKKG HMM: 374-464 ENETA SFWKGPGMNP KKTKTEVFFL PCCAFLEKEG SIANSGRWAQ WRYKAQEPAG QSLPDGDIIY ELFLEIRKLY QKPGGKFPDP ILKLQW ALI: 137-231 DL TLQNPRCVFQ LLAKHYSRYD LDTVSKVTGT PKDDLTKVYE AYSATGVPDK AGTIMYAMGW CQHSVGVQNI RTMSIIQLLL GNMGIAGGGV NAL ENV: 119-238 YDKSSWAYEL DEKGVPKKDL TLQNPRCVFQ LLAKHYSRYD LDTVSKVTGT PKDDLTKVYE AYSATGVPDK AGTIMYAMGW CQHSVGVQNI RTMSIIQLLL GNMGIAGGGV NALRGESNVQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MKDDIITLK VNGKDFKGRE VKGKKGQTVL EVLRANDVHV PTLCYHPQMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSQFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDVAAR GSDSYITTFN NTNLMESNCV SCGQCVQACP VGALTEKKSR FKGRAWEMEK VRTTCPYCGV GCQMWLHVKD GRIVKVTGVE DGAPNEGRLC VKGRFGYDFI YSEERLKTPL IKENGAFREA SWDEALDLVA KKFTEIKKKH GPDAIAGVSS SRSLNEDSYQ MQKLFRAVIG TNNIDNCART
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 14-85 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
PF10588: 91-131 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
PF12838: 153-212 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF04879: 226-281 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF00384: 283-358 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MKDDIITLK VNGKDFKGRE VKGKKGQTVL EVLRANDVHV PTLCYHPQMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSQFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDVAAR GSDSYITTFN NTNLMESNCV SCGQCVQACP VGALTEKKSR FKGRAWEMEK VRTTCPYCGV GCQMWLHVKD GRIVKVTGVE DGAPNEGRLC VKGRFGYDFI YSEERLKTPL IKENGAFREA SWDEALDLVA KKFTEIKKKH GPDAIAGVSS SRSLNEDSYQ MQKLFRAVIG TNNIDNCART HMM: 62-171 NMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSQFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNG ALI: 228-325 K VRTTCPYCGV GCQMWLHVKD GRIVKVTGVE DGAPNEGRLC VKGRFGYDFI YSEERLKTPL IKENGAFREA SWDEALDLVA KKFTEIKKKH GPDAIAG ENV: 211-358 ALTEKKSR FKGRAWEMEK VRTTCPYCGV GCQMWLHVKD GRIVKVTGVE DGAPNEGRLC VKGRFGYDFI YSEERLKTPL IKENGAFREA SWDEALDLVA KKFTEIKKKH GPDAIAGVSS SRSLNEDSYQ MQKLFRAVIG TNNIDNCART Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MKDDIITLK VNGKDFKGRE VKGKKGQTVL EVLRANDVHV PTLCYHPQMP PYGGCRLCIV EIENMRGLPP SCTTPATDGM VVNTHSPKVV GVRKTVLELL LAYGDHNCLL CEQTGSCELQ NLVYEHGIDH VRIKSQFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDVAAR GSDSYITTFN NTNLMESNCV SCGQCVQACP VGALTEKKSR FKGRAWEMEK VRTTCPYCGV GCQMWLHVKD GRIVKVTGVE DGAPNEGRLC VKGRFGYDFI YSEERLKTPL IKENGAFREA SWDEALDLVA KKFTEIKKKH GPDAIAGVSS SRSLNEDSYQ MQKLFRAVIG TNNIDNCART HMM: 127-186 DH VRIKSQFVPK IKDDSHPMIV RDHNKCVLCG RCVRACLQVQ VNGAIDVAAR GSDSYITT ALI: 269-324 VKGRFGYDFI YSEERLKTPL IKENGAFREA SWDEALDLVA KKFTEIKKKH GPDAIA ENV: 255-355 TGVE DGAPNEGRLC VKGRFGYDFI YSEERLKTPL IKENGAFREA SWDEALDLVA KKFTEIKKKH GPDAIAGVSS SRSLNEDSYQ MQKLFRAVIG TNNIDNC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
PF04879: 2-55 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00384: 60-476 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
PF01568: 564-681 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 90-184 SEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVR ALI: 16-103 GCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPES ENV: 5-113 IKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 271-328 PAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA ALI: 189-246 LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWT ENV: 185-248 FQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 400-481 ADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGF ALI: 248-329 G FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA E ENV: 245-342 WTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 604-698 LGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT ALI: 387-479 YV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR M ENV: 370-485 ILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 841-918 ALI: 562-638 FPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA ENV: 547-680 SP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 65-311 LLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVL ALI: 7-245 TH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERW ENV: 2-248 EKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 385-466 CLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAW ALI: 248-328 G FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA ENV: 245-345 WTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 613-683 RISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPC ALI: 409-479 KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR M ENV: 379-485 SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 838-893 ALI: 562-616 FPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRIST ENV: 547-636 SP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 104-317 VAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTG ALI: 42-254 GYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRA ENV: 3-269 KWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 588-646 R TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPE ALI: 388-445 V QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHY ENV: 369-480 WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MSEKWIKTH CARFDHGGCG LEVLVKDGKL VKIRADKTDA YSEGYCCPKG LAGIDRACHP ARLRQPLLRR GPRGEGEWEA IPWERALDIL VSEFRSAMAG GGPESVAFCQ GAPRGLEFFI LLRLANLLNC PNVGAAQHVC HMPREQMAAV TCGFFPVPDY DSPTRCVLLW GSDPQRTNEE GILGVRFQKA LKQGAGLIVV DPLKSGPART ADLWLQIRPG TDDLLAVGLL HVIIEEGLFD RPFVERWTTG FAELRAAVRP FDPATVSLGT GIPAERITSA ARLYAKSRPA MIHWGNAVEH SANTSQTCRS LVLLMALTGN LEAPGGNVKA EAPNVMRPAE LICLKQFPGR IDKLPNRTWG LIPRLLTVPN WILFHSILDA SPYAVQCLYV QATNPLISCS EADKVLQALL KLDFLAVADI FMTPTAAFAD LVLPAATHLE YNDIGHYGLP HGLVFARPKA VDPPGDAWPD IRILNEWGKR MGFGSRFWDT EDRILEAVLE PSGLTYGAFA AKGLLSGPRT HYSYREKGFA TPSGKVELHS SLLEQWGYSP VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL RAIPCSIEKA ESVPAMKSRT P HMM: 821-930 ALI: 562-668 FPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP ENV: 549-678 VPTVGVHAGT DERFPFLLTS RKPRFFFHSA YRQIESLRER TPRPTVMIHP DTASRLGIAA GTPVRISTVS GSVTQFAELT RDIDPEVIFA DFGWWFPERA DEMFAWKESN LNQLTGAGGP TDPIMGTVQL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MKLTRRDFL KISSAATAGL ALSGMGFNLT PVQAYTWELR TKDAKETPTI CCYCAVGCGI ICHTDKKTGQ VIYTEGDADH PINGGSLCAK GASSYQLAQN PKRVTKVLYR APNSDKWVAK DWKWALQEIA KRVKKSRDAS FVEKNAQGQI VNRCMGIASV GSAAMDNEEC WIYQAMLRAL GLVYIEHQAR I
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
PF10518: 1-25 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF04879: 43-97 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
Sequence: MKLTRRDFL KISSAATAGL ALSGMGFNLT PVQAYTWELR TKDAKETPTI CCYCAVGCGI ICHTDKKTGQ VIYTEGDADH PINGGSLCAK GASSYQLAQN PKRVTKVLYR APNSDKWVAK DWKWALQEIA KRVKKSRDAS FVEKNAQGQI VNRCMGIASV GSAAMDNEEC WIYQAMLRAL GLVYIEHQAR I HMM: 4-161 RRDFL KISSAATAGL ALSGMGFNLT PVQAYTWELR TKDAKETPTI CCYCAVGCGI ICHTDKKTGQ VIYTEGDADH PINGGSLCAK GASSYQLAQN PKRVTKVLYR APNSDKWVAK DWKWALQEIA KRVKKSRDAS FVEKNAQGQI VNRCMGIASV GSA ALI: 1-135 KLTRRDFL KISSAATAGL ALSGMGFNLT PVQAYTWELR TKDAKETPTI CCYCAVGCGI ICHTDKKTGQ VIYTEGDADH PINGGSLCAK GASSYQLAQN PKRVTKVLYR APNSDKWVAK DWKWALQEIA KRVKKSR ENV: 1-166 KLTRRDFL KISSAATAGL ALSGMGFNLT PVQAYTWELR TKDAKETPTI CCYCAVGCGI ICHTDKKTGQ VIYTEGDADH PINGGSLCAK GASSYQLAQN PKRVTKVLYR APNSDKWVAK DWKWALQEIA KRVKKSRDAS FVEKNAQGQI VNRCMGIASV GSAAMDNE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MEYRSVLTT CTYCGCGCGF YLTVIDGRVV DTIPCKTNPV NEGKLCIKGW NVHEFVHSPN RLTQPLLRKN GTLTPVSWDE ALDFTASRLR EIKEAHGSDS VAFLASAKVT NEENYLIQKF ARAAVGTNNV DHCARL
10 20 30 40 50 60 70 80 90 100 110 120 130
PF04879: 4-57 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00384: 59-135 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MEYRSVLTT CTYCGCGCGF YLTVIDGRVV DTIPCKTNPV NEGKLCIKGW NVHEFVHSPN RLTQPLLRKN GTLTPVSWDE ALDFTASRLR EIKEAHGSDS VAFLASAKVT NEENYLIQKF ARAAVGTNNV DHCARL HMM: 103-175 ASAKVT NEENYLIQKF ARAAVGTNNV DHCARL ALI: 37-105 PV NEGKLCIKGW NVHEFVHSPN RLTQPLLRKN GTLTPVSWDE ALDFTASRLR EIKEAHGSDS VAFLASA ENV: 11-133 YCGCGCGF YLTVIDGRVV DTIPCKTNPV NEGKLCIKGW NVHEFVHSPN RLTQPLLRKN GTLTPVSWDE ALDFTASRLR EIKEAHGSDS VAFLASAKVT NEENYLIQKF ARAAVGTNNV DHCAR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130
Sequence: MEYRSVLTT CTYCGCGCGF YLTVIDGRVV DTIPCKTNPV NEGKLCIKGW NVHEFVHSPN RLTQPLLRKN GTLTPVSWDE ALDFTASRLR EIKEAHGSDS VAFLASAKVT NEENYLIQKF ARAAVGTNNV DHCARL HMM: 126-187 NNV DHCARL ALI: 44-101 CIKGW NVHEFVHSPN RLTQPLLRKN GTLTPVSWDE ALDFTASRLR EIKEAHGSDS VAF ENV: 2-117 YRSVLTT CTYCGCGCGF YLTVIDGRVV DTIPCKTNPV NEGKLCIKGW NVHEFVHSPN RLTQPLLRKN GTLTPVSWDE ALDFTASRLR EIKEAHGSDS VAFLASAKVT NEENYLIQK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130
Sequence: MEFKSVITT CPICACGCGM WLEVMDGRIV ATAPSKTSPT NRGKLCIKGW NVHEFVQHPD RLKKPLIRKD GVSREVPWDE ALAYTAGELR RIRDAYGPDS IAFLSSARCT NEENYILQKF ARTAVGTNNV DHCARL
10 20 30 40 50 60 70 80 90 100 110 120 130
PF04879: 3-56 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00384: 59-135 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MEFKSVITT CPICACGCGM WLEVMDGRIV ATAPSKTSPT NRGKLCIKGW NVHEFVQHPD RLKKPLIRKD GVSREVPWDE ALAYTAGELR RIRDAYGPDS IAFLSSARCT NEENYILQKF ARTAVGTNNV DHCARL HMM: 101-175 FLSSARCT NEENYILQKF ARTAVGTNNV DHCARL ALI: 35-105 TSPT NRGKLCIKGW NVHEFVQHPD RLKKPLIRKD GVSREVPWDE ALAYTAGELR RIRDAYGPDS IAFLSSA ENV: 19-133 WLEVMDGRIV ATAPSKTSPT NRGKLCIKGW NVHEFVQHPD RLKKPLIRKD GVSREVPWDE ALAYTAGELR RIRDAYGPDS IAFLSSARCT NEENYILQKF ARTAVGTNNV DHCAR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130
Sequence: MDNNIITLK VNGQSVRGKK GQTVLEICRE NGIHIPTLCY HPKMPPYGGC RLCIVEIENM RGLPPSCTTP AVDGMSVHTH TDKVMGVRKT VLELLLAYGN HNCLLCEQTG NCELQDLVYE HGIDHVRFKS DFVPQPLDDA NAMIIRDQNK CVLCGRCVRG CLEVQVNGVI DIAMRGSDSF ITTFDNTELK ESNCVFCGEC VASCPTGALT YKQARFKGRP WDLKKVVTTC TYCGVGCQVE LNVKDNKVVK TTSSFDIPGP NRGSLCVKGR FGNDFIDSPD RLKTPLIKEN GGFREASWDE ALGLVAKRLG EIKAKSGPDA VAFFSSARCT NEENYLLNKF ARAVIGTNNI DHCARL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 5-80 ◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌
PF10588: 86-126 ◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
PF12838: 148-207 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF04879: 222-276 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00384: 279-355 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MDNNIITLK VNGQSVRGKK GQTVLEICRE NGIHIPTLCY HPKMPPYGGC RLCIVEIENM RGLPPSCTTP AVDGMSVHTH TDKVMGVRKT VLELLLAYGN HNCLLCEQTG NCELQDLVYE HGIDHVRFKS DFVPQPLDDA NAMIIRDQNK CVLCGRCVRG CLEVQVNGVI DIAMRGSDSF ITTFDNTELK ESNCVFCGEC VASCPTGALT YKQARFKGRP WDLKKVVTTC TYCGVGCQVE LNVKDNKVVK TTSSFDIPGP NRGSLCVKGR FGNDFIDSPD RLKTPLIKEN GGFREASWDE ALGLVAKRLG EIKAKSGPDA VAFFSSARCT NEENYLLNKF ARAVIGTNNI DHCARL HMM: 58-173 M RGLPPSCTTP AVDGMSVHTH TDKVMGVRKT VLELLLAYGN HNCLLCEQTG NCELQDLVYE HGIDHVRFKS DFVPQPLDDA NAMIIRDQNK CVLCGRCVRG CLEVQVNGVI DIAMR ALI: 219-323 WDLKKVVTTC TYCGVGCQVE LNVKDNKVVK TTSSFDIPGP NRGSLCVKGR FGNDFIDSPD RLKTPLIKEN GGFREASWDE ALGLVAKRLG EIKAKSGPDA VAFFS ENV: 206-352 ALT YKQARFKGRP WDLKKVVTTC TYCGVGCQVE LNVKDNKVVK TTSSFDIPGP NRGSLCVKGR FGNDFIDSPD RLKTPLIKEN GGFREASWDE ALGLVAKRLG EIKAKSGPDA VAFFSSARCT NEENYLLNKF ARAVIGTNNI DHCA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MGVTRREFL LISGTMGAGL ALSSLGVDMR PIMAHAEELS KIEKVKSAKQ TYSLCYYCSV TCGLICSTDQ KTGKIINIEG DPDHPVTEGS LCAKGAASLQ MSARNEHRLT KVLYRKPGGD KWEPKTMDWA LTEIAKRIKA TRDKDFMVKN AKGQVVNRLE SISHLGSSKL DNEECWMVTA AVRALGLVYI DHQARV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
PF04879: 47-99 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MGVTRREFL LISGTMGAGL ALSSLGVDMR PIMAHAEELS KIEKVKSAKQ TYSLCYYCSV TCGLICSTDQ KTGKIINIEG DPDHPVTEGS LCAKGAASLQ MSARNEHRLT KVLYRKPGGD KWEPKTMDWA LTEIAKRIKA TRDKDFMVKN AKGQVVNRLE SISHLGSSKL DNEECWMVTA AVRALGLVYI DHQARV HMM: 6-159 EFL LISGTMGAGL ALSSLGVDMR PIMAHAEELS KIEKVKSAKQ TYSLCYYCSV TCGLICSTDQ KTGKIINIEG DPDHPVTEGS LCAKGAASLQ MSARNEHRLT KVLYRKPGGD KWEPKTMDWA LTEIAKRIKA TRDKDFMVKN AKGQVVNRLE S ALI: 3-138 TRREFL LISGTMGAGL ALSSLGVDMR PIMAHAEELS KIEKVKSAKQ TYSLCYYCSV TCGLICSTDQ KTGKIINIEG DPDHPVTEGS LCAKGAASLQ MSARNEHRLT KVLYRKPGGD KWEPKTMDWA LTEIAKRIKA ENV: 1-173 GVTRREFL LISGTMGAGL ALSSLGVDMR PIMAHAEELS KIEKVKSAKQ TYSLCYYCSV TCGLICSTDQ KTGKIINIEG DPDHPVTEGS LCAKGAASLQ MSARNEHRLT KVLYRKPGGD KWEPKTMDWA LTEIAKRIKA TRDKDFMVKN AKGQVVNRLE SISHLGSSKL DNEEC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MGLVTFWID GRQVRAKSGL TVMEAADELG VVIPRLCFHP ALRPSGSCRL CAVEIDDFRG LPAACSTPVE PGMRVRTATA RVLDFRREML RVILQDHPRE CLGCPRNGTC ELQRLVETVG IDFPYSPEEF GRHRAEQAGR YFERDYDLCV RCGRCVRVCH EVRGAKAIVF REKHGRQEVG TPFDRPLAET GCQFCGACVD VCPVGALREK LPPDGSGGLQ EMSQGCGELS SIVMALYRKE LPRSVKTSVC PVCSAGCSME FEMAGGDGII RVRPSVGEAS NRGQACVQGR FLLKEYLGRS DRLLMPMIRE NGSFRETGWD AALDFIADRF LSYRPEETAV LTDGRCTNEE LRSLREFSRM VLRTDAFGCV CPPGHAAASE ILRETTGTPG GMGCLQELER SDCILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVHPDIAG RWETELKALG EHLSSFHPGE VSRITGVSPE DLVEAACLIG RSETLSVLYG LGVAASPRVA ETVRAMLALL QIKGNLGKPG CVVAPLYGNG NLLGAWEAGM ASGHLSGLPA QGGAYRSGPF DVLAAIDSGK IRALYLACES LEGDALDSIG PLLGKAEFVV VHDVAIPRAI SRAQGGVGDV YLPMAAALEK GGSYLAGGRK VRRIEPVVAP PGEARSVVWV VTELARRMHA RGFDSMDSPV SADESKSCVP ACTAESQGCD RGGPRPTDLC PAEPGGEPAQ RWIGWKPDDP GTPEDPRDAE YPFAVIVKEA LRPYCLGPLL ARESAAFFGS DEELEMNPAD VFGMGMSAGD AARVVTRHGE WEGRIRINDL IPVKTLAVSG SIVRLHVDLR DIAGGAFAAR VVKR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880
PF13510: 3-78 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
PF10588: 84-121 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
PF12838: 147-205 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF04879: 243-293 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF00384: 300-705 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MGLVTFWID GRQVRAKSGL TVMEAADELG VVIPRLCFHP ALRPSGSCRL CAVEIDDFRG LPAACSTPVE PGMRVRTATA RVLDFRREML RVILQDHPRE CLGCPRNGTC ELQRLVETVG IDFPYSPEEF GRHRAEQAGR YFERDYDLCV RCGRCVRVCH EVRGAKAIVF REKHGRQEVG TPFDRPLAET GCQFCGACVD VCPVGALREK LPPDGSGGLQ EMSQGCGELS SIVMALYRKE LPRSVKTSVC PVCSAGCSME FEMAGGDGII RVRPSVGEAS NRGQACVQGR FLLKEYLGRS DRLLMPMIRE NGSFRETGWD AALDFIADRF LSYRPEETAV LTDGRCTNEE LRSLREFSRM VLRTDAFGCV CPPGHAAASE ILRETTGTPG GMGCLQELER SDCILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVHPDIAG RWETELKALG EHLSSFHPGE VSRITGVSPE DLVEAACLIG RSETLSVLYG LGVAASPRVA ETVRAMLALL QIKGNLGKPG CVVAPLYGNG NLLGAWEAGM ASGHLSGLPA QGGAYRSGPF DVLAAIDSGK IRALYLACES LEGDALDSIG PLLGKAEFVV VHDVAIPRAI SRAQGGVGDV YLPMAAALEK GGSYLAGGRK VRRIEPVVAP PGEARSVVWV VTELARRMHA RGFDSMDSPV SADESKSCVP ACTAESQGCD RGGPRPTDLC PAEPGGEPAQ RWIGWKPDDP GTPEDPRDAE YPFAVIVKEA LRPYCLGPLL ARESAAFFGS DEELEMNPAD VFGMGMSAGD AARVVTRHGE WEGRIRINDL IPVKTLAVSG SIVRLHVDLR DIAGGAFAAR VVKR HMM: 121-304 FPYSPEEF GRHRAEQAGR YFERDYDLCV RCGRCVRVCH EVRGAKAIVF REKHGRQEVG TPFDRPLAET GCQFCGACVD VCPVGALREK LPPDGSGGLQ EMSQGCGELS SIVMALYRKE LPRSVKTSVC PVCSAGCSME FEMAGGDGII RVRPSVGEAS NRGQACVQGR FLLKEYLGRS DRLLMP ALI: 296-473 GRS DRLLMPMIRE NGSFRETGWD AALDFIADRF LSYRPEETAV LTDGRCTNEE LRSLREFSRM VLRTDAFGCV CPPGHAAASE ILRETTGTPG GMGCLQELER SDCILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVH ENV: 270-480 VRPSVGEAS NRGQACVQGR FLLKEYLGRS DRLLMPMIRE NGSFRETGWD AALDFIADRF LSYRPEETAV LTDGRCTNEE LRSLREFSRM VLRTDAFGCV CPPGHAAASE ILRETTGTPG GMGCLQELER SDCILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVHPDIAG RW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880
Sequence: MGLVTFWID GRQVRAKSGL TVMEAADELG VVIPRLCFHP ALRPSGSCRL CAVEIDDFRG LPAACSTPVE PGMRVRTATA RVLDFRREML RVILQDHPRE CLGCPRNGTC ELQRLVETVG IDFPYSPEEF GRHRAEQAGR YFERDYDLCV RCGRCVRVCH EVRGAKAIVF REKHGRQEVG TPFDRPLAET GCQFCGACVD VCPVGALREK LPPDGSGGLQ EMSQGCGELS SIVMALYRKE LPRSVKTSVC PVCSAGCSME FEMAGGDGII RVRPSVGEAS NRGQACVQGR FLLKEYLGRS DRLLMPMIRE NGSFRETGWD AALDFIADRF LSYRPEETAV LTDGRCTNEE LRSLREFSRM VLRTDAFGCV CPPGHAAASE ILRETTGTPG GMGCLQELER SDCILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVHPDIAG RWETELKALG EHLSSFHPGE VSRITGVSPE DLVEAACLIG RSETLSVLYG LGVAASPRVA ETVRAMLALL QIKGNLGKPG CVVAPLYGNG NLLGAWEAGM ASGHLSGLPA QGGAYRSGPF DVLAAIDSGK IRALYLACES LEGDALDSIG PLLGKAEFVV VHDVAIPRAI SRAQGGVGDV YLPMAAALEK GGSYLAGGRK VRRIEPVVAP PGEARSVVWV VTELARRMHA RGFDSMDSPV SADESKSCVP ACTAESQGCD RGGPRPTDLC PAEPGGEPAQ RWIGWKPDDP GTPEDPRDAE YPFAVIVKEA LRPYCLGPLL ARESAAFFGS DEELEMNPAD VFGMGMSAGD AARVVTRHGE WEGRIRINDL IPVKTLAVSG SIVRLHVDLR DIAGGAFAAR VVKR HMM: 388-465 G GMGCLQELER SDCILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRL ALI: 486-562 ALG EHLSSFHPGE VSRITGVSPE DLVEAACLIG RSETLSVLYG LGVAASPRVA ETVRAMLALL QIKGNLGKPG CVVA ENV: 480-570 WETELKALG EHLSSFHPGE VSRITGVSPE DLVEAACLIG RSETLSVLYG LGVAASPRVA ETVRAMLALL QIKGNLGKPG CVVAPLYGNG NL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880
Sequence: MGLVTFWID GRQVRAKSGL TVMEAADELG VVIPRLCFHP ALRPSGSCRL CAVEIDDFRG LPAACSTPVE PGMRVRTATA RVLDFRREML RVILQDHPRE CLGCPRNGTC ELQRLVETVG IDFPYSPEEF GRHRAEQAGR YFERDYDLCV RCGRCVRVCH EVRGAKAIVF REKHGRQEVG TPFDRPLAET GCQFCGACVD VCPVGALREK LPPDGSGGLQ EMSQGCGELS SIVMALYRKE LPRSVKTSVC PVCSAGCSME FEMAGGDGII RVRPSVGEAS NRGQACVQGR FLLKEYLGRS DRLLMPMIRE NGSFRETGWD AALDFIADRF LSYRPEETAV LTDGRCTNEE LRSLREFSRM VLRTDAFGCV CPPGHAAASE ILRETTGTPG GMGCLQELER SDCILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVHPDIAG RWETELKALG EHLSSFHPGE VSRITGVSPE DLVEAACLIG RSETLSVLYG LGVAASPRVA ETVRAMLALL QIKGNLGKPG CVVAPLYGNG NLLGAWEAGM ASGHLSGLPA QGGAYRSGPF DVLAAIDSGK IRALYLACES LEGDALDSIG PLLGKAEFVV VHDVAIPRAI SRAQGGVGDV YLPMAAALEK GGSYLAGGRK VRRIEPVVAP PGEARSVVWV VTELARRMHA RGFDSMDSPV SADESKSCVP ACTAESQGCD RGGPRPTDLC PAEPGGEPAQ RWIGWKPDDP GTPEDPRDAE YPFAVIVKEA LRPYCLGPLL ARESAAFFGS DEELEMNPAD VFGMGMSAGD AARVVTRHGE WEGRIRINDL IPVKTLAVSG SIVRLHVDLR DIAGGAFAAR VVKR HMM: 632-688 GKAEFVV VHDVAIPRAI SRAQGGVGDV YLPMAAALEK GGSYLAGGRK VRRIEPVVAP ALI: 657-711 DV YLPMAAALEK GGSYLAGGRK VRRIEPVVAP PGEARSVVWV VTELARRMHA RGF ENV: 648-722 I SRAQGGVGDV YLPMAAALEK GGSYLAGGRK VRRIEPVVAP PGEARSVVWV VTELARRMHA RGFDSMDSPV SADE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880
Sequence: MGLVTFWID GRQVRAKSGL TVMEAADELG VVIPRLCFHP ALRPSGSCRL CAVEIDDFRG LPAACSTPVE PGMRVRTATA RVLDFRREML RVILQDHPRE CLGCPRNGTC ELQRLVETVG IDFPYSPEEF GRHRAEQAGR YFERDYDLCV RCGRCVRVCH EVRGAKAIVF REKHGRQEVG TPFDRPLAET GCQFCGACVD VCPVGALREK LPPDGSGGLQ EMSQGCGELS SIVMALYRKE LPRSVKTSVC PVCSAGCSME FEMAGGDGII RVRPSVGEAS NRGQACVQGR FLLKEYLGRS DRLLMPMIRE NGSFRETGWD AALDFIADRF LSYRPEETAV LTDGRCTNEE LRSLREFSRM VLRTDAFGCV CPPGHAAASE ILRETTGTPG GMGCLQELER SDCILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVHPDIAG RWETELKALG EHLSSFHPGE VSRITGVSPE DLVEAACLIG RSETLSVLYG LGVAASPRVA ETVRAMLALL QIKGNLGKPG CVVAPLYGNG NLLGAWEAGM ASGHLSGLPA QGGAYRSGPF DVLAAIDSGK IRALYLACES LEGDALDSIG PLLGKAEFVV VHDVAIPRAI SRAQGGVGDV YLPMAAALEK GGSYLAGGRK VRRIEPVVAP PGEARSVVWV VTELARRMHA RGFDSMDSPV SADESKSCVP ACTAESQGCD RGGPRPTDLC PAEPGGEPAQ RWIGWKPDDP GTPEDPRDAE YPFAVIVKEA LRPYCLGPLL ARESAAFFGS DEELEMNPAD VFGMGMSAGD AARVVTRHGE WEGRIRINDL IPVKTLAVSG SIVRLHVDLR DIAGGAFAAR VVKR HMM: 153-175 CVRVCH EVRGAKAIVF REKHGRQ ALI: 308-330 E NGSFRETGWD AALDFIADRF LS ENV: 296-334 GRS DRLLMPMIRE NGSFRETGWD AALDFIADRF LSYRPE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880
Sequence: MGLVTFWID GRQVRAKSGL TVMEAADELG VVIPRLCFHP ALRPSGSCRL CAVEIDDFRG LPAACSTPVE PGMRVRTATA RVLDFRREML RVILQDHPRE CLGCPRNGTC ELQRLVETVG IDFPYSPEEF GRHRAEQAGR YFERDYDLCV RCGRCVRVCH EVRGAKAIVF REKHGRQEVG TPFDRPLAET GCQFCGACVD VCPVGALREK LPPDGSGGLQ EMSQGCGELS SIVMALYRKE LPRSVKTSVC PVCSAGCSME FEMAGGDGII RVRPSVGEAS NRGQACVQGR FLLKEYLGRS DRLLMPMIRE NGSFRETGWD AALDFIADRF LSYRPEETAV LTDGRCTNEE LRSLREFSRM VLRTDAFGCV CPPGHAAASE ILRETTGTPG GMGCLQELER SDCILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVHPDIAG RWETELKALG EHLSSFHPGE VSRITGVSPE DLVEAACLIG RSETLSVLYG LGVAASPRVA ETVRAMLALL QIKGNLGKPG CVVAPLYGNG NLLGAWEAGM ASGHLSGLPA QGGAYRSGPF DVLAAIDSGK IRALYLACES LEGDALDSIG PLLGKAEFVV VHDVAIPRAI SRAQGGVGDV YLPMAAALEK GGSYLAGGRK VRRIEPVVAP PGEARSVVWV VTELARRMHA RGFDSMDSPV SADESKSCVP ACTAESQGCD RGGPRPTDLC PAEPGGEPAQ RWIGWKPDDP GTPEDPRDAE YPFAVIVKEA LRPYCLGPLL ARESAAFFGS DEELEMNPAD VFGMGMSAGD AARVVTRHGE WEGRIRINDL IPVKTLAVSG SIVRLHVDLR DIAGGAFAAR VVKR HMM: 268-322 I RVRPSVGEAS NRGQACVQGR FLLKEYLGRS DRLLMPMIRE NGSFRETGWD AALD ALI: 421-475 REAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVHPD ENV: 401-483 CILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVHPDIAG RWETE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880
Sequence: MGLVTFWID GRQVRAKSGL TVMEAADELG VVIPRLCFHP ALRPSGSCRL CAVEIDDFRG LPAACSTPVE PGMRVRTATA RVLDFRREML RVILQDHPRE CLGCPRNGTC ELQRLVETVG IDFPYSPEEF GRHRAEQAGR YFERDYDLCV RCGRCVRVCH EVRGAKAIVF REKHGRQEVG TPFDRPLAET GCQFCGACVD VCPVGALREK LPPDGSGGLQ EMSQGCGELS SIVMALYRKE LPRSVKTSVC PVCSAGCSME FEMAGGDGII RVRPSVGEAS NRGQACVQGR FLLKEYLGRS DRLLMPMIRE NGSFRETGWD AALDFIADRF LSYRPEETAV LTDGRCTNEE LRSLREFSRM VLRTDAFGCV CPPGHAAASE ILRETTGTPG GMGCLQELER SDCILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVHPDIAG RWETELKALG EHLSSFHPGE VSRITGVSPE DLVEAACLIG RSETLSVLYG LGVAASPRVA ETVRAMLALL QIKGNLGKPG CVVAPLYGNG NLLGAWEAGM ASGHLSGLPA QGGAYRSGPF DVLAAIDSGK IRALYLACES LEGDALDSIG PLLGKAEFVV VHDVAIPRAI SRAQGGVGDV YLPMAAALEK GGSYLAGGRK VRRIEPVVAP PGEARSVVWV VTELARRMHA RGFDSMDSPV SADESKSCVP ACTAESQGCD RGGPRPTDLC PAEPGGEPAQ RWIGWKPDDP GTPEDPRDAE YPFAVIVKEA LRPYCLGPLL ARESAAFFGS DEELEMNPAD VFGMGMSAGD AARVVTRHGE WEGRIRINDL IPVKTLAVSG SIVRLHVDLR DIAGGAFAAR VVKR HMM: 402-478 ILLLGLN PPASWPIAGT RLREAALGGT KLVAANPCKV GAARFADVHL QHYPGTETIL VSGLIRLLLD RNEVHPDIAG ALI: 485-561 KALG EHLSSFHPGE VSRITGVSPE DLVEAACLIG RSETLSVLYG LGVAASPRVA ETVRAMLALL QIKGNLGKPG CVV ENV: 478-572 G RWETELKALG EHLSSFHPGE VSRITGVSPE DLVEAACLIG RSETLSVLYG LGVAASPRVA ETVRAMLALL QIKGNLGKPG CVVAPLYGNG NLLG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
PF00384: 1-330 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
PF01568: 412-519 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 242-330 VVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TR ALI: 6-94 ELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEG ENV: 1-95 TNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 402-480 PAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MR ALI: 96-174 EEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNP ENV: 94-183 GFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 619-698 ALI: 254-331 VHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRF ENV: 234-345 AGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIME Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 837-919 ALI: 406-487 VDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVF ENV: 397-495 IE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIES Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 248-314 M MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPV ALI: 28-94 A TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEG ENV: 1-95 TNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 387-469 FS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR G ALI: 96-180 EEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NN ENV: 93-189 EGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 612-683 ALI: 262-331 RNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRF ENV: 255-352 HHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 836-916 ALI: 408-489 S EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM P ENV: 398-498 E YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 227-311 GV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAV ALI: 10-94 SDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEG ENV: 2-101 NSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 387-462 FS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRV ALI: 98-173 F RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVN ENV: 93-184 EGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 613-678 ALI: 266-329 LLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS T ENV: 246-336 NPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIAELE DSDCILVIGS NTTSSHPLVA TRIFRAKEKG AKVIVADPRN VQLVKKADLH IRHNLGTDVA LVNGIMHVIL ARGWHNQAFV DERTEGFEEF RKVIEQYTPE RTAEITGVPA EDIITVADWY ANARAGSIVY CMGITQHTTG VDNVKSLANL SMLTGHIGRE STGVNPLRGQ NNVQGACDMG GLPNVYPGYQ PVNVPANKEK FEAAWNAKLS DKVGLTIPGV LEGLSAGTVK AAYVVGENPM MSDPDVHHVE KALRNAELLV VQDIFLTPTA ELAHVVLPGA SFAEKDGTFS STERRVQRVR QAVKPVGDSR ADWEILQEVS TRFGYPMKYA SPAEIMEEVA RMTPSYGGIT FDRLEGDGLC WPCPTADHPG TKFLHAGKFS RGLGLFHAIE YKPPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LLTNSAHDPI AKIPEYKVCA VSLERAV HMM: 823-899 ALI: 414-489 LTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM P ENV: 401-500 PPAEVVDS EFPFWLTTGR VHVHYHTGTM TRNSPSLHQE MPEGFLELNP QDAQELGVKS GDRVRVVSRR GEMVTRVDLT MRVRQGMVFM PFHFIESCAN LL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MDRYVCTVC GYVYDPAVGD PDNDIAPGTK FEDLPEDWVC PVCGAAKSDF EKE
10 20 30 40 50
PF00301: 2-49 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MDRYVCTVC GYVYDPAVGD PDNDIAPGTK FEDLPEDWVC PVCGAAKSDF EKE HMM: 425-468 ALI: 3-46 YVCTVC GYVYDPAVGD PDNDIAPGTK FEDLPEDWVC PVCGAAKS ENV: 1-52 DRYVCTVC GYVYDPAVGD PDNDIAPGTK FEDLPEDWVC PVCGAAKSDF EKE Position: 10 20 30 40 50
Sequence: MEKWRCIPC DYIYDPAEGD EEGGIEPGIA FEGLPEDWVC PICGAGKDQF EKVE
10 20 30 40 50
PF00301: 2-49 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MEKWRCIPC DYIYDPAEGD EEGGIEPGIA FEGLPEDWVC PICGAGKDQF EKVE HMM: 425-469 ALI: 3-47 WRCIPC DYIYDPAEGD EEGGIEPGIA FEGLPEDWVC PICGAGKDQ ENV: 1-53 EKWRCIPC DYIYDPAEGD EEGGIEPGIA FEGLPEDWVC PICGAGKDQF EKVE Position: 10 20 30 40 50
Sequence: MSKPEEMWR CQTVNCGYVY DPDRGDRKGK IPKGTSFEDL PDSWKCPVCG GTKKCFRPLA GPGSVGETPC ELPTGK
10 20 30 40 50 60 70
PF00301: 6-55 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
Sequence: MSKPEEMWR CQTVNCGYVY DPDRGDRKGK IPKGTSFEDL PDSWKCPVCG GTKKCFRPLA GPGSVGETPC ELPTGK HMM: 422-469 ALI: 6-53 MWR CQTVNCGYVY DPDRGDRKGK IPKGTSFEDL PDSWKCPVCG GTKKC ENV: 1-61 SKPEEMWR CQTVNCGYVY DPDRGDRKGK IPKGTSFEDL PDSWKCPVCG GTKKCFRPLA GPG Position: 10 20 30 40 50 60 70
Sequence: METSNGSTF GSVMVVGGGV AGIQAALDLA NAGFYVYLVE RASAIGGAMS QLDKTFPTND CSMCILSPKL VECGSHPSIR LLTTSELTAL EGDVGRFRAK VLQHPRYVDL SKCISCGACA EKCPAVVSDA YNAGLGKRKA IYKLYAQATP SGYAIDAANC RRIGRGKKCS VCAKFCPAGA VDYTQQEQVL DLEVGAVILS AGFQAFDPAG LDTYLYNDHP NVVTSLEFER ILSASGPFMG HLVRPSDHAE PRRIAWIQCV GSRNVNHCEN GYCSSVCCMY AIKEAIVAKE HSKEPLDATV FFMDMRTYGK DFEKYYNRAQ SEYGVKFVRS RVHTIDRAPG DRLSISYTTE AGEQSEEQFD MVVLSVGMEV SAEATALAGR LGISLNSYRF AETSSFAPVS TSRPGVYVCG VLQGPKDIPF AVAEASAAAG AAAGDLADSR GTRVKVRELP PELDLGDESP RIGVFVCNCG INIGSVVKVP EVVEYAAKLP HVVWTEENLF TCSQDTQERI RQAIKEHRLN RVVVAACSPR THEPLFQDTL KGCGLNKYLF EMANIRDQDS WVHQKEPGNA TEKAVDLVRM AVARAALLKP LIERPLEINQ KALVIGGGIS GLNAALNLAR QGFEVALVEK EKELGGIARR LHHTIEGLDV QSYLAELVRE VRGNGRIEVL SDTVVAGYKG YKGNFVTEVR TNSGEERRTI DHGVAIVATG AVEYKPTEFL HGEHPMVMTQ LDLGRLIHED GRGISKWRRV VMVQCVGSRN EQNPNCSRIC CQNAVKNALT LKELNPDLEI IILYRDMRMY GMLEDYYTKA RQEGILFCRY QQANPPAVTS ENGALRVTFS DHVLNRSIQA GVDAVVLSAG TVAADNERLA TLLKVPRNAE GFFIEAHAKL RPVDFSSEGI YLCGMAHGPK LISESIAQAM AAASRAGAFL SSKDLTIGGV VARVDPSLCA ACLVCVRSCP YGVPQINKDD VSEINEALCQ GCGICASECP AKAIRLAHYA DDQIMVKVDA LLEGVL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
PF07992: 600-921 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
PF00037: 971-994 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
Sequence: METSNGSTF GSVMVVGGGV AGIQAALDLA NAGFYVYLVE RASAIGGAMS QLDKTFPTND CSMCILSPKL VECGSHPSIR LLTTSELTAL EGDVGRFRAK VLQHPRYVDL SKCISCGACA EKCPAVVSDA YNAGLGKRKA IYKLYAQATP SGYAIDAANC RRIGRGKKCS VCAKFCPAGA VDYTQQEQVL DLEVGAVILS AGFQAFDPAG LDTYLYNDHP NVVTSLEFER ILSASGPFMG HLVRPSDHAE PRRIAWIQCV GSRNVNHCEN GYCSSVCCMY AIKEAIVAKE HSKEPLDATV FFMDMRTYGK DFEKYYNRAQ SEYGVKFVRS RVHTIDRAPG DRLSISYTTE AGEQSEEQFD MVVLSVGMEV SAEATALAGR LGISLNSYRF AETSSFAPVS TSRPGVYVCG VLQGPKDIPF AVAEASAAAG AAAGDLADSR GTRVKVRELP PELDLGDESP RIGVFVCNCG INIGSVVKVP EVVEYAAKLP HVVWTEENLF TCSQDTQERI RQAIKEHRLN RVVVAACSPR THEPLFQDTL KGCGLNKYLF EMANIRDQDS WVHQKEPGNA TEKAVDLVRM AVARAALLKP LIERPLEINQ KALVIGGGIS GLNAALNLAR QGFEVALVEK EKELGGIARR LHHTIEGLDV QSYLAELVRE VRGNGRIEVL SDTVVAGYKG YKGNFVTEVR TNSGEERRTI DHGVAIVATG AVEYKPTEFL HGEHPMVMTQ LDLGRLIHED GRGISKWRRV VMVQCVGSRN EQNPNCSRIC CQNAVKNALT LKELNPDLEI IILYRDMRMY GMLEDYYTKA RQEGILFCRY QQANPPAVTS ENGALRVTFS DHVLNRSIQA GVDAVVLSAG TVAADNERLA TLLKVPRNAE GFFIEAHAKL RPVDFSSEGI YLCGMAHGPK LISESIAQAM AAASRAGAFL SSKDLTIGGV VARVDPSLCA ACLVCVRSCP YGVPQINKDD VSEINEALCQ GCGICASECP AKAIRLAHYA DDQIMVKVDA LLEGVL HMM: 7-46 TF GSVMVVGGGV AGIQAALDLA NAGFYVYLVE RASAIGGA ALI: 11-48 VMVVGGGV AGIQAALDLA NAGFYVYLVE RASAIGGAMS ENV: 6-65 STF GSVMVVGGGV AGIQAALDLA NAGFYVYLVE RASAIGGAMS QLDKTFPTND CSMCILS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
Sequence: METSNGSTF GSVMVVGGGV AGIQAALDLA NAGFYVYLVE RASAIGGAMS QLDKTFPTND CSMCILSPKL VECGSHPSIR LLTTSELTAL EGDVGRFRAK VLQHPRYVDL SKCISCGACA EKCPAVVSDA YNAGLGKRKA IYKLYAQATP SGYAIDAANC RRIGRGKKCS VCAKFCPAGA VDYTQQEQVL DLEVGAVILS AGFQAFDPAG LDTYLYNDHP NVVTSLEFER ILSASGPFMG HLVRPSDHAE PRRIAWIQCV GSRNVNHCEN GYCSSVCCMY AIKEAIVAKE HSKEPLDATV FFMDMRTYGK DFEKYYNRAQ SEYGVKFVRS RVHTIDRAPG DRLSISYTTE AGEQSEEQFD MVVLSVGMEV SAEATALAGR LGISLNSYRF AETSSFAPVS TSRPGVYVCG VLQGPKDIPF AVAEASAAAG AAAGDLADSR GTRVKVRELP PELDLGDESP RIGVFVCNCG INIGSVVKVP EVVEYAAKLP HVVWTEENLF TCSQDTQERI RQAIKEHRLN RVVVAACSPR THEPLFQDTL KGCGLNKYLF EMANIRDQDS WVHQKEPGNA TEKAVDLVRM AVARAALLKP LIERPLEINQ KALVIGGGIS GLNAALNLAR QGFEVALVEK EKELGGIARR LHHTIEGLDV QSYLAELVRE VRGNGRIEVL SDTVVAGYKG YKGNFVTEVR TNSGEERRTI DHGVAIVATG AVEYKPTEFL HGEHPMVMTQ LDLGRLIHED GRGISKWRRV VMVQCVGSRN EQNPNCSRIC CQNAVKNALT LKELNPDLEI IILYRDMRMY GMLEDYYTKA RQEGILFCRY QQANPPAVTS ENGALRVTFS DHVLNRSIQA GVDAVVLSAG TVAADNERLA TLLKVPRNAE GFFIEAHAKL RPVDFSSEGI YLCGMAHGPK LISESIAQAM AAASRAGAFL SSKDLTIGGV VARVDPSLCA ACLVCVRSCP YGVPQINKDD VSEINEALCQ GCGICASECP AKAIRLAHYA DDQIMVKVDA LLEGVL HMM: 8-45 F GSVMVVGGGV AGIQAALDLA NAGFYVYLVE RASAIGG ALI: 601-636 LVIGGGIS GLNAALNLAR QGFEVALVEK EKELGGIA ENV: 596-714 INQ KALVIGGGIS GLNAALNLAR QGFEVALVEK EKELGGIARR LHHTIEGLDV QSYLAELVRE VRGNGRIEVL SDTVVAGYKG YKGNFVTEVR TNSGEERRTI DHGVAIVATG AVEYKP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010
Sequence: MQRRIGFYV CHCGTNIAGK VAVDEVAAFV RTLKNVVVAR SYKFMCSDPG QEMIQKDIRE LNLNRVVVAS CSPRLHEKTF QSACERAKLN PYYFQMACIR EHCSWVTEDP AKATEKAKTL AAAAVNRVNH HEKLWAREVS VHPDVLVIGA GIAGIQASLD IAKADRQVYL VEKEPSIGGH MVQFDKTFPT LDCAACISTP KTVAVSQSPK IKLFSYSEVV EVSGFVGNYS VKVRRKPRYV IEERCTGCGL CAEACPVSVP NAFDEALSLR KAVYRNFPQA VPITFVIDKK EQAPCRIACP AGINVQGYIQ LIGKGKYREA VQLIMERLPL PGVLGRVCPH PCESMCRRAA VDTPLAIRDL KRYAADQVNL EDLPLPHIEE RPEKAAVIGS GPAGLSAAYF LRLKGYQVTI FEALPLLGGM LRVGIPDYRL PQDVLDKEIG YLLRLGVKAE TGKKLGRDFS LDDLRNDGYR VIFLGIGAHR SLKLNVPGED SYQGVVDALE FLREVNLGEK SLPGRRIVIV GGGNVAIDAS RVALRLGCEE VTIVYRRTRE EMPAYAEEID AALEEGVKIN YLTAPVGIRG EANKVTGFEV IRTELGEPDQ SGRRRPVPVK GSEFVIPCDA VISAIGQEPE AETCGAGDLN LSRRGTIVVD RSSMQTSIPD VFAGGDAVVG PATVIEAVAA GRRAAEAMHR YVTEGIEGLA GIEPEKTGAD GGDWREIPEG TPQVPRASLH HRSFEQSRLD FEEAAIGLAD GDIARETERC LNCGVCSECM ECVRACERSA IDHGAVEEII DLKVGSIIVA TGFDVMDPSP LKQYGYGRFD EVYTGLEFER LNNAVGPTGG QILMKNGGKP ESVGIIHCVG SRDVNHHEYC SRVCCMYALK YGHLIKEKAG HDTRVYNFYI DMRCFGKGYE EFYRRLQEEK VTFIRGRPAE ITDQAESPLE QGKLVIVAED TLSGRMLRVP VDMVILCSAM EARAEAPEVA RVFGINQGGD GFFLEEHPKL GPMTTPTDGV FLAGACQGPK DIPDTVSHAS GAAAQALALS TRGKVQISPT VSFIDPDICA GCQGCIKLCP YSAIEFDERR GVSVVNEALC KGCGSCAGFC PSGAARVRHF SAKQLFAEIE GLLDSAV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120
PF12831: 142-181 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF00037: 237-257 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF14691: 290-368 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF07992: 383-680 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌
PF12838: 1057-1103 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
Sequence: MQRRIGFYV CHCGTNIAGK VAVDEVAAFV RTLKNVVVAR SYKFMCSDPG QEMIQKDIRE LNLNRVVVAS CSPRLHEKTF QSACERAKLN PYYFQMACIR EHCSWVTEDP AKATEKAKTL AAAAVNRVNH HEKLWAREVS VHPDVLVIGA GIAGIQASLD IAKADRQVYL VEKEPSIGGH MVQFDKTFPT LDCAACISTP KTVAVSQSPK IKLFSYSEVV EVSGFVGNYS VKVRRKPRYV IEERCTGCGL CAEACPVSVP NAFDEALSLR KAVYRNFPQA VPITFVIDKK EQAPCRIACP AGINVQGYIQ LIGKGKYREA VQLIMERLPL PGVLGRVCPH PCESMCRRAA VDTPLAIRDL KRYAADQVNL EDLPLPHIEE RPEKAAVIGS GPAGLSAAYF LRLKGYQVTI FEALPLLGGM LRVGIPDYRL PQDVLDKEIG YLLRLGVKAE TGKKLGRDFS LDDLRNDGYR VIFLGIGAHR SLKLNVPGED SYQGVVDALE FLREVNLGEK SLPGRRIVIV GGGNVAIDAS RVALRLGCEE VTIVYRRTRE EMPAYAEEID AALEEGVKIN YLTAPVGIRG EANKVTGFEV IRTELGEPDQ SGRRRPVPVK GSEFVIPCDA VISAIGQEPE AETCGAGDLN LSRRGTIVVD RSSMQTSIPD VFAGGDAVVG PATVIEAVAA GRRAAEAMHR YVTEGIEGLA GIEPEKTGAD GGDWREIPEG TPQVPRASLH HRSFEQSRLD FEEAAIGLAD GDIARETERC LNCGVCSECM ECVRACERSA IDHGAVEEII DLKVGSIIVA TGFDVMDPSP LKQYGYGRFD EVYTGLEFER LNNAVGPTGG QILMKNGGKP ESVGIIHCVG SRDVNHHEYC SRVCCMYALK YGHLIKEKAG HDTRVYNFYI DMRCFGKGYE EFYRRLQEEK VTFIRGRPAE ITDQAESPLE QGKLVIVAED TLSGRMLRVP VDMVILCSAM EARAEAPEVA RVFGINQGGD GFFLEEHPKL GPMTTPTDGV FLAGACQGPK DIPDTVSHAS GAAAQALALS TRGKVQISPT VSFIDPDICA GCQGCIKLCP YSAIEFDERR GVSVVNEALC KGCGSCAGFC PSGAARVRHF SAKQLFAEIE GLLDSAV HMM: 187-233 PT LDCAACISTP KTVAVSQSPK IKLFSYSEVV EVSGFVGNYS VKVRR ALI: 18-63 K VAVDEVAAFV RTLKNVVVAR SYKFMCSDPG QEMIQKDIRE LNLNR ENV: 13-78 TNIAGK VAVDEVAAFV RTLKNVVVAR SYKFMCSDPG QEMIQKDIRE LNLNRVVVAS CSPRLHEKTF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120
Sequence: MQRRIGFYV CHCGTNIAGK VAVDEVAAFV RTLKNVVVAR SYKFMCSDPG QEMIQKDIRE LNLNRVVVAS CSPRLHEKTF QSACERAKLN PYYFQMACIR EHCSWVTEDP AKATEKAKTL AAAAVNRVNH HEKLWAREVS VHPDVLVIGA GIAGIQASLD IAKADRQVYL VEKEPSIGGH MVQFDKTFPT LDCAACISTP KTVAVSQSPK IKLFSYSEVV EVSGFVGNYS VKVRRKPRYV IEERCTGCGL CAEACPVSVP NAFDEALSLR KAVYRNFPQA VPITFVIDKK EQAPCRIACP AGINVQGYIQ LIGKGKYREA VQLIMERLPL PGVLGRVCPH PCESMCRRAA VDTPLAIRDL KRYAADQVNL EDLPLPHIEE RPEKAAVIGS GPAGLSAAYF LRLKGYQVTI FEALPLLGGM LRVGIPDYRL PQDVLDKEIG YLLRLGVKAE TGKKLGRDFS LDDLRNDGYR VIFLGIGAHR SLKLNVPGED SYQGVVDALE FLREVNLGEK SLPGRRIVIV GGGNVAIDAS RVALRLGCEE VTIVYRRTRE EMPAYAEEID AALEEGVKIN YLTAPVGIRG EANKVTGFEV IRTELGEPDQ SGRRRPVPVK GSEFVIPCDA VISAIGQEPE AETCGAGDLN LSRRGTIVVD RSSMQTSIPD VFAGGDAVVG PATVIEAVAA GRRAAEAMHR YVTEGIEGLA GIEPEKTGAD GGDWREIPEG TPQVPRASLH HRSFEQSRLD FEEAAIGLAD GDIARETERC LNCGVCSECM ECVRACERSA IDHGAVEEII DLKVGSIIVA TGFDVMDPSP LKQYGYGRFD EVYTGLEFER LNNAVGPTGG QILMKNGGKP ESVGIIHCVG SRDVNHHEYC SRVCCMYALK YGHLIKEKAG HDTRVYNFYI DMRCFGKGYE EFYRRLQEEK VTFIRGRPAE ITDQAESPLE QGKLVIVAED TLSGRMLRVP VDMVILCSAM EARAEAPEVA RVFGINQGGD GFFLEEHPKL GPMTTPTDGV FLAGACQGPK DIPDTVSHAS GAAAQALALS TRGKVQISPT VSFIDPDICA GCQGCIKLCP YSAIEFDERR GVSVVNEALC KGCGSCAGFC PSGAARVRHF SAKQLFAEIE GLLDSAV HMM: 5-46 GFYV CHCGTNIAGK VAVDEVAAFV RTLKNVVVAR SYKFMCSD ALI: 141-180 PDVLVIGA GIAGIQASLD IAKADRQVYL VEKEPSIGGH MV ENV: 138-191 S VHPDVLVIGA GIAGIQASLD IAKADRQVYL VEKEPSIGGH MVQFDKTFPT LDC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120
Sequence: MQRRIGFYV CHCGTNIAGK VAVDEVAAFV RTLKNVVVAR SYKFMCSDPG QEMIQKDIRE LNLNRVVVAS CSPRLHEKTF QSACERAKLN PYYFQMACIR EHCSWVTEDP AKATEKAKTL AAAAVNRVNH HEKLWAREVS VHPDVLVIGA GIAGIQASLD IAKADRQVYL VEKEPSIGGH MVQFDKTFPT LDCAACISTP KTVAVSQSPK IKLFSYSEVV EVSGFVGNYS VKVRRKPRYV IEERCTGCGL CAEACPVSVP NAFDEALSLR KAVYRNFPQA VPITFVIDKK EQAPCRIACP AGINVQGYIQ LIGKGKYREA VQLIMERLPL PGVLGRVCPH PCESMCRRAA VDTPLAIRDL KRYAADQVNL EDLPLPHIEE RPEKAAVIGS GPAGLSAAYF LRLKGYQVTI FEALPLLGGM LRVGIPDYRL PQDVLDKEIG YLLRLGVKAE TGKKLGRDFS LDDLRNDGYR VIFLGIGAHR SLKLNVPGED SYQGVVDALE FLREVNLGEK SLPGRRIVIV GGGNVAIDAS RVALRLGCEE VTIVYRRTRE EMPAYAEEID AALEEGVKIN YLTAPVGIRG EANKVTGFEV IRTELGEPDQ SGRRRPVPVK GSEFVIPCDA VISAIGQEPE AETCGAGDLN LSRRGTIVVD RSSMQTSIPD VFAGGDAVVG PATVIEAVAA GRRAAEAMHR YVTEGIEGLA GIEPEKTGAD GGDWREIPEG TPQVPRASLH HRSFEQSRLD FEEAAIGLAD GDIARETERC LNCGVCSECM ECVRACERSA IDHGAVEEII DLKVGSIIVA TGFDVMDPSP LKQYGYGRFD EVYTGLEFER LNNAVGPTGG QILMKNGGKP ESVGIIHCVG SRDVNHHEYC SRVCCMYALK YGHLIKEKAG HDTRVYNFYI DMRCFGKGYE EFYRRLQEEK VTFIRGRPAE ITDQAESPLE QGKLVIVAED TLSGRMLRVP VDMVILCSAM EARAEAPEVA RVFGINQGGD GFFLEEHPKL GPMTTPTDGV FLAGACQGPK DIPDTVSHAS GAAAQALALS TRGKVQISPT VSFIDPDICA GCQGCIKLCP YSAIEFDERR GVSVVNEALC KGCGSCAGFC PSGAARVRHF SAKQLFAEIE GLLDSAV HMM: 176-192 GGH MVQFDKTFPT LDCA ALI: 511-527 PGRRIVIV GGGNVAIDA ENV: 484-545 VPGED SYQGVVDALE FLREVNLGEK SLPGRRIVIV GGGNVAIDAS RVALRLGCEE VTIVYRR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120
Sequence: MQRRIGFYV CHCGTNIAGK VAVDEVAAFV RTLKNVVVAR SYKFMCSDPG QEMIQKDIRE LNLNRVVVAS CSPRLHEKTF QSACERAKLN PYYFQMACIR EHCSWVTEDP AKATEKAKTL AAAAVNRVNH HEKLWAREVS VHPDVLVIGA GIAGIQASLD IAKADRQVYL VEKEPSIGGH MVQFDKTFPT LDCAACISTP KTVAVSQSPK IKLFSYSEVV EVSGFVGNYS VKVRRKPRYV IEERCTGCGL CAEACPVSVP NAFDEALSLR KAVYRNFPQA VPITFVIDKK EQAPCRIACP AGINVQGYIQ LIGKGKYREA VQLIMERLPL PGVLGRVCPH PCESMCRRAA VDTPLAIRDL KRYAADQVNL EDLPLPHIEE RPEKAAVIGS GPAGLSAAYF LRLKGYQVTI FEALPLLGGM LRVGIPDYRL PQDVLDKEIG YLLRLGVKAE TGKKLGRDFS LDDLRNDGYR VIFLGIGAHR SLKLNVPGED SYQGVVDALE FLREVNLGEK SLPGRRIVIV GGGNVAIDAS RVALRLGCEE VTIVYRRTRE EMPAYAEEID AALEEGVKIN YLTAPVGIRG EANKVTGFEV IRTELGEPDQ SGRRRPVPVK GSEFVIPCDA VISAIGQEPE AETCGAGDLN LSRRGTIVVD RSSMQTSIPD VFAGGDAVVG PATVIEAVAA GRRAAEAMHR YVTEGIEGLA GIEPEKTGAD GGDWREIPEG TPQVPRASLH HRSFEQSRLD FEEAAIGLAD GDIARETERC LNCGVCSECM ECVRACERSA IDHGAVEEII DLKVGSIIVA TGFDVMDPSP LKQYGYGRFD EVYTGLEFER LNNAVGPTGG QILMKNGGKP ESVGIIHCVG SRDVNHHEYC SRVCCMYALK YGHLIKEKAG HDTRVYNFYI DMRCFGKGYE EFYRRLQEEK VTFIRGRPAE ITDQAESPLE QGKLVIVAED TLSGRMLRVP VDMVILCSAM EARAEAPEVA RVFGINQGGD GFFLEEHPKL GPMTTPTDGV FLAGACQGPK DIPDTVSHAS GAAAQALALS TRGKVQISPT VSFIDPDICA GCQGCIKLCP YSAIEFDERR GVSVVNEALC KGCGSCAGFC PSGAARVRHF SAKQLFAEIE GLLDSAV HMM: 5-48 GFYV CHCGTNIAGK VAVDEVAAFV RTLKNVVVAR SYKFMCSDPG ALI: 142-183 DVLVIGA GIAGIQASLD IAKADRQVYL VEKEPSIGGH MVQFD ENV: 138-225 S VHPDVLVIGA GIAGIQASLD IAKADRQVYL VEKEPSIGGH MVQFDKTFPT LDCAACISTP KTVAVSQSPK IKLFSYSEVV EVSGFVG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120
Sequence: MQRRIGFYV CHCGTNIAGK VAVDEVAAFV RTLKNVVVAR SYKFMCSDPG QEMIQKDIRE LNLNRVVVAS CSPRLHEKTF QSACERAKLN PYYFQMACIR EHCSWVTEDP AKATEKAKTL AAAAVNRVNH HEKLWAREVS VHPDVLVIGA GIAGIQASLD IAKADRQVYL VEKEPSIGGH MVQFDKTFPT LDCAACISTP KTVAVSQSPK IKLFSYSEVV EVSGFVGNYS VKVRRKPRYV IEERCTGCGL CAEACPVSVP NAFDEALSLR KAVYRNFPQA VPITFVIDKK EQAPCRIACP AGINVQGYIQ LIGKGKYREA VQLIMERLPL PGVLGRVCPH PCESMCRRAA VDTPLAIRDL KRYAADQVNL EDLPLPHIEE RPEKAAVIGS GPAGLSAAYF LRLKGYQVTI FEALPLLGGM LRVGIPDYRL PQDVLDKEIG YLLRLGVKAE TGKKLGRDFS LDDLRNDGYR VIFLGIGAHR SLKLNVPGED SYQGVVDALE FLREVNLGEK SLPGRRIVIV GGGNVAIDAS RVALRLGCEE VTIVYRRTRE EMPAYAEEID AALEEGVKIN YLTAPVGIRG EANKVTGFEV IRTELGEPDQ SGRRRPVPVK GSEFVIPCDA VISAIGQEPE AETCGAGDLN LSRRGTIVVD RSSMQTSIPD VFAGGDAVVG PATVIEAVAA GRRAAEAMHR YVTEGIEGLA GIEPEKTGAD GGDWREIPEG TPQVPRASLH HRSFEQSRLD FEEAAIGLAD GDIARETERC LNCGVCSECM ECVRACERSA IDHGAVEEII DLKVGSIIVA TGFDVMDPSP LKQYGYGRFD EVYTGLEFER LNNAVGPTGG QILMKNGGKP ESVGIIHCVG SRDVNHHEYC SRVCCMYALK YGHLIKEKAG HDTRVYNFYI DMRCFGKGYE EFYRRLQEEK VTFIRGRPAE ITDQAESPLE QGKLVIVAED TLSGRMLRVP VDMVILCSAM EARAEAPEVA RVFGINQGGD GFFLEEHPKL GPMTTPTDGV FLAGACQGPK DIPDTVSHAS GAAAQALALS TRGKVQISPT VSFIDPDICA GCQGCIKLCP YSAIEFDERR GVSVVNEALC KGCGSCAGFC PSGAARVRHF SAKQLFAEIE GLLDSAV HMM: 175-209 IGGH MVQFDKTFPT LDCAACISTP KTVAVSQSPK I ALI: 512-546 GRRIVIV GGGNVAIDAS RVALRLGCEE VTIVYRRT ENV: 486-560 GED SYQGVVDALE FLREVNLGEK SLPGRRIVIV GGGNVAIDAS RVALRLGCEE VTIVYRRTRE EMPAYAEEID AA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120
Sequence: MKTVTACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVYPTIGR NILEASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELRAKCFI EAKRPAVAYP GMVFAHSDGK CRFPPELHPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630
PF04879: 2-53 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF00384: 57-452 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MKTVTACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVYPTIGR NILEASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELRAKCFI EAKRPAVAYP GMVFAHSDGK CRFPPELHPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE HMM: 115-327 FALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDF ALI: 31-235 NPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHT ENV: 18-287 V ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630
Sequence: MKTVTACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVYPTIGR NILEASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELRAKCFI EAKRPAVAYP GMVFAHSDGK CRFPPELHPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE HMM: 450-483 GRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELR ALI: 287-320 RY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LH ENV: 278-328 A TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630
Sequence: MKTVTACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVYPTIGR NILEASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELRAKCFI EAKRPAVAYP GMVFAHSDGK CRFPPELHPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE HMM: 627-697 YE QYVRLETE ALI: 383-452 EKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRR ENV: 354-455 SAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630
Sequence: MKTVTACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVYPTIGR NILEASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELRAKCFI EAKRPAVAYP GMVFAHSDGK CRFPPELHPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE HMM: 95-302 ILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALA ALI: 30-229 GNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG E ENV: 5-250 ACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630
Sequence: MKTVTACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVYPTIGR NILEASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELRAKCFI EAKRPAVAYP GMVFAHSDGK CRFPPELHPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE HMM: 422-461 LHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPD ALI: 276-315 PVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGS ENV: 242-327 RELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630
Sequence: MKTVTACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVYPTIGR NILEASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELRAKCFI EAKRPAVAYP GMVFAHSDGK CRFPPELHPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE HMM: 591-681 HPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE ALI: 366-454 SNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLD ENV: 352-457 EASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630
Sequence: MKTVTACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVYPTIGR NILEASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELRAKCFI EAKRPAVAYP GMVFAHSDGK CRFPPELHPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE HMM: 106-309 VLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM G ALI: 38-233 A GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLT ENV: 23-248 NGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630
Sequence: MKTVTACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVYPTIGR NILEASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELRAKCFI EAKRPAVAYP GMVFAHSDGK CRFPPELHPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE HMM: 400-481 RHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEE ALI: 251-332 AGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKG ENV: 236-343 KGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630
Sequence: MKTVTACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVYPTIGR NILEASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELRAKCFI EAKRPAVAYP GMVFAHSDGK CRFPPELHPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE HMM: 612-684 LIAAGLT DMGSGAPFYE QYVRLETE ALI: 383-454 EKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLD ENV: 356-458 PPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630
Sequence: MKTVTACTL DCPDSCSLVV ETSPNGKTTL RGNPDHPVTA GFVCRKARNF VKRLRSPYRI TSPLLRRGGE WLRLGWDEAL DLCARKIGEY RREPQSILHV HGEGAKGVLK QASKLFFALL GSSRVKGSLC DSAGYVAYVA DFGSRDNNSV TDLLNARAIV NWGRDLSRSS VHTAAVVERA RRGGTRVLTV SPGGMSNASA SDITVRIRPG TDRFLAAAVI RRLIERERIG EELLTHTKGW EDFRELVLAR DPAGLAAACE VNDEDIERIY SFYADGGPVA TIVGTGLQRY LHGGENVRFI NALAVLSGNM GRSGGGSHYH LHSLHSVDFG WAKGPAESSR RTLVYPTIGR NILEASAPPV RMLWVNGSNF VNQAPDSLQT VRALEKIKFK VVVDAFMTDT ARHADLVLPC ALILEQEDIV ASYLHDFVHH VKKVFDPPGE ARTDYEILSE LGRRLDPPIL LPDPQTCFRA ALDRPNIEGT LEELRAKCFI EAKRPAVAYP GMVFAHSDGK CRFPPELHPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR RGDWMSAGGG ANRLIAAGLT DMGSGAPFYE QYVRLETE HMM: 838-914 ALI: 525-596 YPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVL ENV: 516-599 HPE PPPPEGYPLR LLTLIRGDSI HSQIPQEDQA ARPTVWIAPE NPFAESGERL ENAWVVSPLG RLRVEVRLMA GLHPAVVLYR R Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630
Sequence: MSNDVLVIG GGIAGIQAAL DLADMGVRVH MVEKLPSIGG KMAQLDKTFP TNDCAI
10 20 30 40 50
PF12831: 3-42 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
Sequence: MSNDVLVIG GGIAGIQAAL DLADMGVRVH MVEKLPSIGG KMAQLDKTFP TNDCAI HMM: 7-45 IG GGIAGIQAAL DLADMGVRVH MVEKLPSIGG KMAQLDK ALI: 4-40 VLVIG GGIAGIQAAL DLADMGVRVH MVEKLPSIGG KM ENV: 1-49 SNDVLVIG GGIAGIQAAL DLADMGVRVH MVEKLPSIGG KMAQLDKTFP T Position: 10 20 30 40 50
Sequence: MSNDVLVIG GGIAGIQAAL DLADMGVRVH MVEKLPSIGG KMAQLDKTFP TNDCAI HMM: 6-44 VIG GGIAGIQAAL DLADMGVRVH MVEKLPSIGG KMAQLD ALI: 4-40 VLVIG GGIAGIQAAL DLADMGVRVH MVEKLPSIGG KM ENV: 1-50 SNDVLVIG GGIAGIQAAL DLADMGVRVH MVEKLPSIGG KMAQLDKTFP TN Position: 10 20 30 40 50
Sequence: MMSEAGEHT ARRGETGGGK PRLNLNRLEM PKQSPGERRR NFSEVATGYT YEMAMEEASR CIQCKKRNCR EGCPVNVDIP DFIRLLQQGN VEGASRVLKA KTSLPGICGR VCPQESQCEH ACTLNKKGAP IAIGRLERFI ADWERTEGTV TTPEIAPSTG KRVAVVGSGP SGLTVASDLA IRGHAVTMFE ALHVAGGVLM YGIPEFRLPK DIVQREVRYV ASLGVDIRLD TVIGINYSLD ELLNADYHAV YLATGAGLPQ FLGVPGENLN MVYSANEFLT RTNLMKAYLH PEYATPVKMG KRVAVIGGGN VAMDSARCAV RLGAREVYVI YRRTRREMPA RLEEVENAEE EGIHFHFLCT PTAFISDGRN NVAAMELLRM KLGEPDAGGR RRPVPIPGSE YAMDIDTVVV SLGTSPNPLI ASTTPDLETT RRGTVTIDDK GKTSKALVWA GGDIVSGGAT VISAMGEGRR AATAMHEYLS R
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
PF14691: 36-147 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF07992: 159-467 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MMSEAGEHT ARRGETGGGK PRLNLNRLEM PKQSPGERRR NFSEVATGYT YEMAMEEASR CIQCKKRNCR EGCPVNVDIP DFIRLLQQGN VEGASRVLKA KTSLPGICGR VCPQESQCEH ACTLNKKGAP IAIGRLERFI ADWERTEGTV TTPEIAPSTG KRVAVVGSGP SGLTVASDLA IRGHAVTMFE ALHVAGGVLM YGIPEFRLPK DIVQREVRYV ASLGVDIRLD TVIGINYSLD ELLNADYHAV YLATGAGLPQ FLGVPGENLN MVYSANEFLT RTNLMKAYLH PEYATPVKMG KRVAVIGGGN VAMDSARCAV RLGAREVYVI YRRTRREMPA RLEEVENAEE EGIHFHFLCT PTAFISDGRN NVAAMELLRM KLGEPDAGGR RRPVPIPGSE YAMDIDTVVV SLGTSPNPLI ASTTPDLETT RRGTVTIDDK GKTSKALVWA GGDIVSGGAT VISAMGEGRR AATAMHEYLS R HMM: 171-208 LTVASDLA IRGHAVTMFE ALHVAGGVLM YGIPEFRLPK ALI: 152-189 EIAPSTG KRVAVVGSGP SGLTVASDLA IRGHAVTMFE A ENV: 139-215 ADWERTEGTV TTPEIAPSTG KRVAVVGSGP SGLTVASDLA IRGHAVTMFE ALHVAGGVLM YGIPEFRLPK DIVQREV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MMSEAGEHT ARRGETGGGK PRLNLNRLEM PKQSPGERRR NFSEVATGYT YEMAMEEASR CIQCKKRNCR EGCPVNVDIP DFIRLLQQGN VEGASRVLKA KTSLPGICGR VCPQESQCEH ACTLNKKGAP IAIGRLERFI ADWERTEGTV TTPEIAPSTG KRVAVVGSGP SGLTVASDLA IRGHAVTMFE ALHVAGGVLM YGIPEFRLPK DIVQREVRYV ASLGVDIRLD TVIGINYSLD ELLNADYHAV YLATGAGLPQ FLGVPGENLN MVYSANEFLT RTNLMKAYLH PEYATPVKMG KRVAVIGGGN VAMDSARCAV RLGAREVYVI YRRTRREMPA RLEEVENAEE EGIHFHFLCT PTAFISDGRN NVAAMELLRM KLGEPDAGGR RRPVPIPGSE YAMDIDTVVV SLGTSPNPLI ASTTPDLETT RRGTVTIDDK GKTSKALVWA GGDIVSGGAT VISAMGEGRR AATAMHEYLS R HMM: 177-191 LA IRGHAVTMFE ALH ALI: 298-312 G KRVAVIGGGN VAMD ENV: 280-332 TNLMKAYLH PEYATPVKMG KRVAVIGGGN VAMDSARCAV RLGAREVYVI YRRT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MPKQAGSST PGESQLGAEV EDQLRAAFKA LPHDMPVFLF TDGKSKDPLG AAAKQMMRLF RNLSDRIKVK EYDMDHPEAR KWNVTGAPTF LFDPERYSIR YMGTPFGEEG RTFLGALILI GSGTGSLSEQ SRKVLKKIDS PRDVKVFVSP TCPYCPEQAI NAIRAAIENP EFISLEIIDI QANPELADKY GAFSVPQTFA NDVLIAQGAQ TEELFLLSLE KMEQQNVFIP ESDAAVLDVD LVIVGGGPAG LTAGIYAVRS GLRTAVVEAG QLGGQVAATP IVENYPGFTR VPGKTLVDIL VSHALEYTEI FQGEKVLEII RGDPLEVRTT RRKFLTRAVI LATGAEYKKL GVPGEARLAG RGVSYCATCD GPLFKGKKVI VVGGGNSAAT EALYLHNIGV GVTMVHRRDT FRAQEHLTRN VLGNNIPVFW DTEVKEIRGK ERVSEVELFN GKTGRTQTVP TDGVFIAVGY SPTVELALKA GVEITPDGFI KHDSHHRTNI PGIYSAGDVE GGYKQIVTAM SQGTEAALSV FEDLKTPYWL SEAVVKAAG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540
PF13192: 141-213 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌
PF07992: 238-522 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
Sequence: MPKQAGSST PGESQLGAEV EDQLRAAFKA LPHDMPVFLF TDGKSKDPLG AAAKQMMRLF RNLSDRIKVK EYDMDHPEAR KWNVTGAPTF LFDPERYSIR YMGTPFGEEG RTFLGALILI GSGTGSLSEQ SRKVLKKIDS PRDVKVFVSP TCPYCPEQAI NAIRAAIENP EFISLEIIDI QANPELADKY GAFSVPQTFA NDVLIAQGAQ TEELFLLSLE KMEQQNVFIP ESDAAVLDVD LVIVGGGPAG LTAGIYAVRS GLRTAVVEAG QLGGQVAATP IVENYPGFTR VPGKTLVDIL VSHALEYTEI FQGEKVLEII RGDPLEVRTT RRKFLTRAVI LATGAEYKKL GVPGEARLAG RGVSYCATCD GPLFKGKKVI VVGGGNSAAT EALYLHNIGV GVTMVHRRDT FRAQEHLTRN VLGNNIPVFW DTEVKEIRGK ERVSEVELFN GKTGRTQTVP TDGVFIAVGY SPTVELALKA GVEITPDGFI KHDSHHRTNI PGIYSAGDVE GGYKQIVTAM SQGTEAALSV FEDLKTPYWL SEAVVKAAG HMM: 154-215 PEQAI NAIRAAIENP EFISLEIIDI QANPELADKY GAFSVPQTFA NDVLIAQGAQ TEELFLL ALI: 351-412 PGEARLAG RGVSYCATCD GPLFKGKKVI VVGGGNSAAT EALYLHNIGV GVTMVHRRDT FRAQ ENV: 328-425 T RRKFLTRAVI LATGAEYKKL GVPGEARLAG RGVSYCATCD GPLFKGKKVI VVGGGNSAAT EALYLHNIGV GVTMVHRRDT FRAQEHLTRN VLGNNIP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540
Sequence: MNEREFTRV TLHTTAEVRW GDEVVTGEVE NLSLNGVFVK SSAQVPADTP VEITILLVGA SSELSVRIKG EVVRREPHGF AVRFQGMNLD SFFHLRSFFV ARNADEKAIR AEYREHIRKK GS
10 20 30 40 50 60 70 80 90 100 110 120
PF07238: 2-95 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MNEREFTRV TLHTTAEVRW GDEVVTGEVE NLSLNGVFVK SSAQVPADTP VEITILLVGA SSELSVRIKG EVVRREPHGF AVRFQGMNLD SFFHLRSFFV ARNADEKAIR AEYREHIRKK GS HMM: 311-364 ALI: 21-74 EVVTGEVE NLSLNGVFVK SSAQVPADTP VEITILLVGA SSELSVRIKG EVVRRE ENV: 13-115 TAEVRW GDEVVTGEVE NLSLNGVFVK SSAQVPADTP VEITILLVGA SSELSVRIKG EVVRREPHGF AVRFQGMNLD SFFHLRSFFV ARNADEKAIR AEYREHI Position: 10 20 30 40 50 60 70 80 90 100 110 120
Sequence: MNQKGASAL VIGAGISGIR SALDLAEMGH HVLLVDKAPN LGGTLRQLDH QFPTDHCGMC RMLPMTERDT CSQFCLRKGL FHDNIEIMLS TELAALQGEP GKFVATLRYR PSLIDPERCN GCGECTRVCP VEVPDEFNAG LATRKAVYLP VPHNLPNSYV IDTDACNHCG ACQNACPTGA IDLNLEARRS FRILVVDDEL VVRDSIKEWL DEAGFAVDMA ASGAEAVEML GRQSYGLLFL DVKMPGMDGV EVLKIAKEMH PELPAVMMTA YATIETAVEA MKVGAKDYIM KPFDIEALTE MAVQTYQATL EVPERRVEVG AVILATGAVP ADPRAGANTY EYGTLPDVVT SVEFERLISG TGPTGGQLLR PSDGKPIRRI AWLQCVGSRN LAEGAPHCSS VCCMFSIKEA VLAKQKTDGA VEAMIFYMDM RTFGKDFQQY RDNAEREHGI GFVRSRVHSV EPGGDAGGIR IAFADADGAM HDEPFDLAVL AVGQKPGGGL EELAATVGIE LNQAGFCRVQ DYSSNRTARD GVFVSGSASS PKDISESVIQ ANSASLSASL LLHSKGKSLV EISEPEEMFR DVSREPSRLA VAICSCGGAI AEKVDPTSLI ADLTQDGYAA HGFTIDRLCT RAGWAQLEEA LASTGANRVL IGACMPYVYR RKLRELGKSL KLDPAFMEVT DIHTPVHSQP ESSEQGPRSA VYAVLSMAAA KLKGAEPFPR TRDEAVPAAL IVGGGISGMT AALSVADHGY KVHLIERNPE LGGNLRLLKR FLQEPQPEAL LEKTLSAVAN HPHITVHTGT RVVHSQGRLG HFVTTVETQD GSGESIEHGV AILSTGGVEF NSEAYLHGRN DAVVTQMEFE DQFHSGKLDA SGLGTVVMIQ CVESREGSRN YCSRVCCLSA LKNAFQLKER NPDTAVYILY RDIMTYGLFE EHYTRARREG VLFVRYETDR KPRVSDENGR LKLVTYDPVL GRELVLEPDL VVLGTGMVPN DSHGLADIFG LETDEHGFLR EAEYKWRPVD TMKSGVFLCG TAHSPRTVPE SVAMAEAAAQ RALGVLRRGR LTSASVTASV RHSLCSLCER CVVACPFHAR WYDEEEERIV VDEFVCQGCG ACSAACPNGA AILHGFQDRQ VHAVLDAALD
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130
PF00890: 7-44 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF12838: 1073-1119 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
PF00072: 191-300 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
PF07992: 728-1048 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MNQKGASAL VIGAGISGIR SALDLAEMGH HVLLVDKAPN LGGTLRQLDH QFPTDHCGMC RMLPMTERDT CSQFCLRKGL FHDNIEIMLS TELAALQGEP GKFVATLRYR PSLIDPERCN GCGECTRVCP VEVPDEFNAG LATRKAVYLP VPHNLPNSYV IDTDACNHCG ACQNACPTGA IDLNLEARRS FRILVVDDEL VVRDSIKEWL DEAGFAVDMA ASGAEAVEML GRQSYGLLFL DVKMPGMDGV EVLKIAKEMH PELPAVMMTA YATIETAVEA MKVGAKDYIM KPFDIEALTE MAVQTYQATL EVPERRVEVG AVILATGAVP ADPRAGANTY EYGTLPDVVT SVEFERLISG TGPTGGQLLR PSDGKPIRRI AWLQCVGSRN LAEGAPHCSS VCCMFSIKEA VLAKQKTDGA VEAMIFYMDM RTFGKDFQQY RDNAEREHGI GFVRSRVHSV EPGGDAGGIR IAFADADGAM HDEPFDLAVL AVGQKPGGGL EELAATVGIE LNQAGFCRVQ DYSSNRTARD GVFVSGSASS PKDISESVIQ ANSASLSASL LLHSKGKSLV EISEPEEMFR DVSREPSRLA VAICSCGGAI AEKVDPTSLI ADLTQDGYAA HGFTIDRLCT RAGWAQLEEA LASTGANRVL IGACMPYVYR RKLRELGKSL KLDPAFMEVT DIHTPVHSQP ESSEQGPRSA VYAVLSMAAA KLKGAEPFPR TRDEAVPAAL IVGGGISGMT AALSVADHGY KVHLIERNPE LGGNLRLLKR FLQEPQPEAL LEKTLSAVAN HPHITVHTGT RVVHSQGRLG HFVTTVETQD GSGESIEHGV AILSTGGVEF NSEAYLHGRN DAVVTQMEFE DQFHSGKLDA SGLGTVVMIQ CVESREGSRN YCSRVCCLSA LKNAFQLKER NPDTAVYILY RDIMTYGLFE EHYTRARREG VLFVRYETDR KPRVSDENGR LKLVTYDPVL GRELVLEPDL VVLGTGMVPN DSHGLADIFG LETDEHGFLR EAEYKWRPVD TMKSGVFLCG TAHSPRTVPE SVAMAEAAAQ RALGVLRRGR LTSASVTASV RHSLCSLCER CVVACPFHAR WYDEEEERIV VDEFVCQGCG ACSAACPNGA AILHGFQDRQ VHAVLDAALD HMM: 2-46 QKGASAL VIGAGISGIR SALDLAEMGH HVLLVDKAPN LGGTLRQL ALI: 2-44 QKGASAL VIGAGISGIR SALDLAEMGH HVLLVDKAPN LGGTLR ENV: 1-52 NQKGASAL VIGAGISGIR SALDLAEMGH HVLLVDKAPN LGGTLRQLDH QFPT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130
Sequence: MNQKGASAL VIGAGISGIR SALDLAEMGH HVLLVDKAPN LGGTLRQLDH QFPTDHCGMC RMLPMTERDT CSQFCLRKGL FHDNIEIMLS TELAALQGEP GKFVATLRYR PSLIDPERCN GCGECTRVCP VEVPDEFNAG LATRKAVYLP VPHNLPNSYV IDTDACNHCG ACQNACPTGA IDLNLEARRS FRILVVDDEL VVRDSIKEWL DEAGFAVDMA ASGAEAVEML GRQSYGLLFL DVKMPGMDGV EVLKIAKEMH PELPAVMMTA YATIETAVEA MKVGAKDYIM KPFDIEALTE MAVQTYQATL EVPERRVEVG AVILATGAVP ADPRAGANTY EYGTLPDVVT SVEFERLISG TGPTGGQLLR PSDGKPIRRI AWLQCVGSRN LAEGAPHCSS VCCMFSIKEA VLAKQKTDGA VEAMIFYMDM RTFGKDFQQY RDNAEREHGI GFVRSRVHSV EPGGDAGGIR IAFADADGAM HDEPFDLAVL AVGQKPGGGL EELAATVGIE LNQAGFCRVQ DYSSNRTARD GVFVSGSASS PKDISESVIQ ANSASLSASL LLHSKGKSLV EISEPEEMFR DVSREPSRLA VAICSCGGAI AEKVDPTSLI ADLTQDGYAA HGFTIDRLCT RAGWAQLEEA LASTGANRVL IGACMPYVYR RKLRELGKSL KLDPAFMEVT DIHTPVHSQP ESSEQGPRSA VYAVLSMAAA KLKGAEPFPR TRDEAVPAAL IVGGGISGMT AALSVADHGY KVHLIERNPE LGGNLRLLKR FLQEPQPEAL LEKTLSAVAN HPHITVHTGT RVVHSQGRLG HFVTTVETQD GSGESIEHGV AILSTGGVEF NSEAYLHGRN DAVVTQMEFE DQFHSGKLDA SGLGTVVMIQ CVESREGSRN YCSRVCCLSA LKNAFQLKER NPDTAVYILY RDIMTYGLFE EHYTRARREG VLFVRYETDR KPRVSDENGR LKLVTYDPVL GRELVLEPDL VVLGTGMVPN DSHGLADIFG LETDEHGFLR EAEYKWRPVD TMKSGVFLCG TAHSPRTVPE SVAMAEAAAQ RALGVLRRGR LTSASVTASV RHSLCSLCER CVVACPFHAR WYDEEEERIV VDEFVCQGCG ACSAACPNGA AILHGFQDRQ VHAVLDAALD HMM: 8-50 L VIGAGISGIR SALDLAEMGH HVLLVDKAPN LGGTLRQLDH QF ALI: 728-768 L IVGGGISGMT AALSVADHGY KVHLIERNPE LGGNLRLLKR ENV: 722-770 EAVPAAL IVGGGISGMT AALSVADHGY KVHLIERNPE LGGNLRLLKR FL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130
Sequence: MSNQPYIRI PGVENGHRLE SRILEERIQK AVESGCRYLE IEAYGQHGLG GRLWRAGEDP VYVKITGSVG QRVGSMGFPN TRIEVFGPGS DDVGWLNGGA EITIHGNAAN GIGNAMAQGK IYVAGNTGAR GMTMTKRNPR FEPPELWVLG SVGDYFAEFM AGGIAVVCGY EPQNPENVLG YRPCVGMVGG RIYFRGPHKG YSRADARLMP LSDEDWSWLS GNLKTYLRAI NRLELLDQLE DREQWQSLIA RGPQEKYAKP ARSMAAFRRE IWDEELGRGG LIGDLTDLDR GPISIITTGH LRRYVPVWEN RKYAAPCEAS CPTGMPVHER WRLIRAGRID EAVDLALSYT PFPASVCGYL CPNLCMQGCT RGTINMAPVD VSQLGKASIK ARLPELPPLS GKRVAVIGGG PAGISVAWQL RRKGHETVIY DTRGALGGKI SALIPSSRIP GDVIDAEVER IREAIPHVHL QQKLDRGDVE QLKADNDFVV VAVGANKPRV IPIPGKERMI PALDFLLQSK SGRIQVGRRV VIVGAGNVGC DAATEAFRLG AEEVTLVDIQ EPLSFGKERK AAEEAGASFR WPCFSKAVTE EGLELTSGEV IPADTVIISV GDMPDLDFLP ETVAVERGFV KVDESYQTTD PQVFAIGDAV KLGLLTDAIG AGRKAAQAIS DILEGKRPRG DARKMIDYNR IRLEYFDPRM LKFDGIEQCA SQCSSCGACR DCGICVTMCP QTAISRQEKD NPFGFEMVVD PDRCIGCGFC AGSCPCGIWD LVENDPLE
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770
PF01493: 56-198 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF14691: 312-385 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF07992: 400-657 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
PF12838: 716-767 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
Sequence: MSNQPYIRI PGVENGHRLE SRILEERIQK AVESGCRYLE IEAYGQHGLG GRLWRAGEDP VYVKITGSVG QRVGSMGFPN TRIEVFGPGS DDVGWLNGGA EITIHGNAAN GIGNAMAQGK IYVAGNTGAR GMTMTKRNPR FEPPELWVLG SVGDYFAEFM AGGIAVVCGY EPQNPENVLG YRPCVGMVGG RIYFRGPHKG YSRADARLMP LSDEDWSWLS GNLKTYLRAI NRLELLDQLE DREQWQSLIA RGPQEKYAKP ARSMAAFRRE IWDEELGRGG LIGDLTDLDR GPISIITTGH LRRYVPVWEN RKYAAPCEAS CPTGMPVHER WRLIRAGRID EAVDLALSYT PFPASVCGYL CPNLCMQGCT RGTINMAPVD VSQLGKASIK ARLPELPPLS GKRVAVIGGG PAGISVAWQL RRKGHETVIY DTRGALGGKI SALIPSSRIP GDVIDAEVER IREAIPHVHL QQKLDRGDVE QLKADNDFVV VAVGANKPRV IPIPGKERMI PALDFLLQSK SGRIQVGRRV VIVGAGNVGC DAATEAFRLG AEEVTLVDIQ EPLSFGKERK AAEEAGASFR WPCFSKAVTE EGLELTSGEV IPADTVIISV GDMPDLDFLP ETVAVERGFV KVDESYQTTD PQVFAIGDAV KLGLLTDAIG AGRKAAQAIS DILEGKRPRG DARKMIDYNR IRLEYFDPRM LKFDGIEQCA SQCSSCGACR DCGICVTMCP QTAISRQEKD NPFGFEMVVD PDRCIGCGFC AGSCPCGIWD LVENDPLE HMM: 174-203 ENVLG YRPCVGMVGG RIYFRGPHKG YSRAD ALI: 396-425 PLS GKRVAVIGGG PAGISVAWQL RRKGHET ENV: 384-438 KASIK ARLPELPPLS GKRVAVIGGG PAGISVAWQL RRKGHETVIY DTRGALGGKI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770
Sequence: MSNQPYIRI PGVENGHRLE SRILEERIQK AVESGCRYLE IEAYGQHGLG GRLWRAGEDP VYVKITGSVG QRVGSMGFPN TRIEVFGPGS DDVGWLNGGA EITIHGNAAN GIGNAMAQGK IYVAGNTGAR GMTMTKRNPR FEPPELWVLG SVGDYFAEFM AGGIAVVCGY EPQNPENVLG YRPCVGMVGG RIYFRGPHKG YSRADARLMP LSDEDWSWLS GNLKTYLRAI NRLELLDQLE DREQWQSLIA RGPQEKYAKP ARSMAAFRRE IWDEELGRGG LIGDLTDLDR GPISIITTGH LRRYVPVWEN RKYAAPCEAS CPTGMPVHER WRLIRAGRID EAVDLALSYT PFPASVCGYL CPNLCMQGCT RGTINMAPVD VSQLGKASIK ARLPELPPLS GKRVAVIGGG PAGISVAWQL RRKGHETVIY DTRGALGGKI SALIPSSRIP GDVIDAEVER IREAIPHVHL QQKLDRGDVE QLKADNDFVV VAVGANKPRV IPIPGKERMI PALDFLLQSK SGRIQVGRRV VIVGAGNVGC DAATEAFRLG AEEVTLVDIQ EPLSFGKERK AAEEAGASFR WPCFSKAVTE EGLELTSGEV IPADTVIISV GDMPDLDFLP ETVAVERGFV KVDESYQTTD PQVFAIGDAV KLGLLTDAIG AGRKAAQAIS DILEGKRPRG DARKMIDYNR IRLEYFDPRM LKFDGIEQCA SQCSSCGACR DCGICVTMCP QTAISRQEKD NPFGFEMVVD PDRCIGCGFC AGSCPCGIWD LVENDPLE HMM: 319-344 CPTGMPVHER WRLIRAGRID EAVDLA ALI: 585-610 AVTE EGLELTSGEV IPADTVIISV GD ENV: 582-629 FSKAVTE EGLELTSGEV IPADTVIISV GDMPDLDFLP ETVAVERGFV K Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770
Sequence: MGKTNGLTA QPRIGVYVCH CGLNIGRTVD CGAVAQAASV LEDVVVARDI PYACSEPGQQ GIKEDISEHR LDRVVVASCS PRLHEPTFRQ MVNAAGINPY LMEMANLREH CSWVHMNDPV AATEKAVDLT KMAVARVRGL RPLEPVRLPL NKKTLVIGGG IAGIQAALDL ADNGYDVVLV ERKPSIGGTM AKLDKTFPTM DCSI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
PF12831: 153-190 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
Sequence: MGKTNGLTA QPRIGVYVCH CGLNIGRTVD CGAVAQAASV LEDVVVARDI PYACSEPGQQ GIKEDISEHR LDRVVVASCS PRLHEPTFRQ MVNAAGINPY LMEMANLREH CSWVHMNDPV AATEKAVDLT KMAVARVRGL RPLEPVRLPL NKKTLVIGGG IAGIQAALDL ADNGYDVVLV ERKPSIGGTM AKLDKTFPTM DCSI HMM: 8-46 A QPRIGVYVCH CGLNIGRTVD CGAVAQAASV LEDVVVAR ALI: 153-189 LVIGGG IAGIQAALDL ADNGYDVVLV ERKPSIGGTM A ENV: 149-198 NKKTLVIGGG IAGIQAALDL ADNGYDVVLV ERKPSIGGTM AKLDKTFPTM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MGKTNGLTA QPRIGVYVCH CGLNIGRTVD CGAVAQAASV LEDVVVARDI PYACSEPGQQ GIKEDISEHR LDRVVVASCS PRLHEPTFRQ MVNAAGINPY LMEMANLREH CSWVHMNDPV AATEKAVDLT KMAVARVRGL RPLEPVRLPL NKKTLVIGGG IAGIQAALDL ADNGYDVVLV ERKPSIGGTM AKLDKTFPTM DCSI HMM: 7-45 TA QPRIGVYVCH CGLNIGRTVD CGAVAQAASV LEDVVVA ALI: 153-189 LVIGGG IAGIQAALDL ADNGYDVVLV ERKPSIGGTM A ENV: 149-199 NKKTLVIGGG IAGIQAALDL ADNGYDVVLV ERKPSIGGTM AKLDKTFPTM D Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MSMKTAFRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLGHPRR VLEHILNNID IESDITLSEG ILDVLDHSAP EPLFGSKIGI DATRRLPGEK ERPAARPVGA LPDAERIASA LRDVSEFLVA FHVPDLEVRN RLLCVNFLKN GSVPAQSFAQ QLLDHPVLQP FAIFLLYDAT IDLRDGSLIL WKLFNNVDPR RDTVRSGGRI VVDATKKGPE DGHHRPWPDD IVMDPEVAAR VARRAKELGI EAFLPAGS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
PF01977: 13-429 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
Sequence: MSMKTAFRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLGHPRR VLEHILNNID IESDITLSEG ILDVLDHSAP EPLFGSKIGI DATRRLPGEK ERPAARPVGA LPDAERIASA LRDVSEFLVA FHVPDLEVRN RLLCVNFLKN GSVPAQSFAQ QLLDHPVLQP FAIFLLYDAT IDLRDGSLIL WKLFNNVDPR RDTVRSGGRI VVDATKKGPE DGHHRPWPDD IVMDPEVAAR VARRAKELGI EAFLPAGS HMM: 2-385 MKTAFRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQ ALI: 7-404 RN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLG ENV: 6-417 FRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLGHPRR VLEHILNNI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MSMKTAFRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLGHPRR VLEHILNNID IESDITLSEG ILDVLDHSAP EPLFGSKIGI DATRRLPGEK ERPAARPVGA LPDAERIASA LRDVSEFLVA FHVPDLEVRN RLLCVNFLKN GSVPAQSFAQ QLLDHPVLQP FAIFLLYDAT IDLRDGSLIL WKLFNNVDPR RDTVRSGGRI VVDATKKGPE DGHHRPWPDD IVMDPEVAAR VARRAKELGI EAFLPAGS HMM: 3-450 KTAFRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLGHPRR VLEHILNNID IESDITLSEG ILDVLDHSAP EPLFGSKIGI DA ALI: 7-457 RN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLGHPRR VLEHILNNID IESDITLSEG ILDVLDHSAP EPLFGSKIGI DATRRLPGE ENV: 5-470 AFRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLGHPRR VLEHILNNID IESDITLSEG ILDVLDHSAP EPLFGSKIGI DATRRLPGEK ERPAARPVGA LP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MSMKTAFRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLGHPRR VLEHILNNID IESDITLSEG ILDVLDHSAP EPLFGSKIGI DATRRLPGEK ERPAARPVGA LPDAERIASA LRDVSEFLVA FHVPDLEVRN RLLCVNFLKN GSVPAQSFAQ QLLDHPVLQP FAIFLLYDAT IDLRDGSLIL WKLFNNVDPR RDTVRSGGRI VVDATKKGPE DGHHRPWPDD IVMDPEVAAR VARRAKELGI EAFLPAGS HMM: 433-477 LDHSAP EPLFGSKIGI DATRRLPGEK ERPAARPVGA LPDAERIAS ALI: 562-606 VRSGGRI VVDATKKGPE DGHHRPWPDD IVMDPEVAAR VARRAKEL ENV: 526-612 LQP FAIFLLYDAT IDLRDGSLIL WKLFNNVDPR RDTVRSGGRI VVDATKKGPE DGHHRPWPDD IVMDPEVAAR VARRAKELGI EAFL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MSMKTAFRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLGHPRR VLEHILNNID IESDITLSEG ILDVLDHSAP EPLFGSKIGI DATRRLPGEK ERPAARPVGA LPDAERIASA LRDVSEFLVA FHVPDLEVRN RLLCVNFLKN GSVPAQSFAQ QLLDHPVLQP FAIFLLYDAT IDLRDGSLIL WKLFNNVDPR RDTVRSGGRI VVDATKKGPE DGHHRPWPDD IVMDPEVAAR VARRAKELGI EAFLPAGS HMM: 2-393 MKTAFRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKA ALI: 6-414 FRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLGHPRR VLEHIL ENV: 5-425 AFRN LQDFIADLER AGELLRIKAP VSSDLEITQI TDLASKSPGG GKALLFENVE GSRFPVLTNA FGSERRICMA LGVSHLDELA RRLKSFIEMK PPKSLADALR LIPLGLELLR FLPRKTRKAP CQEVVTTGRD VDLSMLPVLK CWPSDGGPFV TLPVVITRSL VTGKRNAGMY RLQVYDRKTT GMHWHIHKDG SHYFQEFRER GKRMPVAVAI GTDPAVTYAA TAPLPRGIDE MMLAGFIRRK PVPMVRCLTV DLEVPAESEF VLEGYVDPGE LRVEGPFGDH TGYYSLVGEY PVFHVTALTH RRNPVYFATV VGRPPMEDCF LAKATERIFL PLLNAVFPEI GDYWMPWEGV FHNITVLSIR KEYPGHARRM MSAIWGQGQM SFCKAAVLAD PSVDLGHPRR VLEHILNNID IESDITL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MNREVLVIG GGIAGIQASL DLAEMGIKVH LVERLPSIGG KMSQLDKTFP TNDCAL
10 20 30 40 50
PF12831: 3-43 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
Sequence: MNREVLVIG GGIAGIQASL DLAEMGIKVH LVERLPSIGG KMSQLDKTFP TNDCAL HMM: 7-45 IG GGIAGIQASL DLAEMGIKVH LVERLPSIGG KMSQLDK ALI: 4-40 VLVIG GGIAGIQASL DLAEMGIKVH LVERLPSIGG KM ENV: 1-49 NREVLVIG GGIAGIQASL DLAEMGIKVH LVERLPSIGG KMSQLDKTFP T Position: 10 20 30 40 50
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
PF04879: 4-52 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF00384: 58-482 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF01568: 571-680 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD HMM: 100-310 HSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII ML ALI: 33-241 PHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRR ENV: 20-246 TVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD HMM: 389-462 LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQA ALI: 249-322 LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGG ENV: 242-343 WVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD HMM: 610-684 RLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALD ALI: 409-484 ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLG ENV: 404-490 SATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD HMM: 871-920 ALI: 601-650 LWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FG ENV: 573-659 LLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD HMM: 95-307 ERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSI ALI: 31-241 GNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRR ENV: 18-254 K VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD HMM: 609-678 ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG ALI: 411-481 DKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LAD ENV: 386-486 IKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD HMM: 782-935 ALI: 532-685 GLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDE ENV: 522-691 EKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD HMM: 123-326 GSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFK ALI: 40-241 GALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRR ENV: 21-244 VENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD HMM: 403-480 ASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LA ALI: 248-326 E LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFK ENV: 244-335 LGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD HMM: 625-700 RGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD ALI: 409-485 ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGA ENV: 393-489 RFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY L Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MTRDVYSLC FMCTIRCPIK VTVENDEVLW IEGNPHVPGI EGALCAKGSA GVALLQDHER LRHPMIRTGP RGSGQWRRAS WDEALDFVAD RLRGIIERHG AHSILWGERT NLNTHISKAF MKGIGSPNHF THDALCKGSV NTAFRSLTGY DDTQVGVDYA NTKHIVMYGR NLFEALEIKA INNLLSAMGK GAKLTYIDPR VTVTASKATR YWMIRPGTDL ALNYALMHVI LEEGLFDAEF VRRWVLGLEE LRAFVEPFTP ARAEEETGIP AAEITALARE LAEDKPAVAF HYGYRGAHHT NEVYLRRSII MLNALMGSIE TPGGLFFKKG MKTAGYGELG KYAAQEFPKI AGPRFDGSGS TRFPIADPAH GNPQALAQAI LSEQPYPIKA LIANRFEPLQ SIPDASATRE ALDKLDLLVS IDINMNEFAW CADVVLPESM YLERGDSIQA VSGLKPQLCI RQQAVTPRHD TKPGWLIVKQ LADRLGAGKY LPFETIEDIW NFQLQGTGLT VEELQARGFI SLTEKPIFWD RANGLPFKTP SGKIEFVSSL LENAGFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FGNTVPVQTR ACMKGASDAL LQENVSDFAG GSPALDETQV RVKRLD HMM: 843-918 ALI: 571-645 FRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFM ENV: 553-650 GFPSFP AYARVEPLSE GSFRLLVGRC AVHTHGSTQN NPYLNELVSE NELWINSSAA ARLGITDGCP VEVSSSRGAA TIRAKVTEFI HPEAVFMLHG FG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MENKHLHGT SLIAKLQDDP KVKVDNPIKI GDLTFRDGHQ SLFATRGRTE DLLPIAEEMN KIGYWSMEVW GGATFDTMHR FLNEDPWERP RQLKKYLKDT PMMMLLRGQN LVGYRNYADD MAEAFVDRAC INGIDIFRTF DAVNDFRNFE TVIKPIKKHK KHFQGTICYS LTEPRMGGPV YNLDYYVKKA KQLENMGADT VCIKDMAGLI APYDAYYLVK ALKENVKVPI HLHSHFTSGM ADLALLKAIE AGVDIVDTCL APWAYRSSHP AIEPLVMTLR HTSRDTGFDL HQLAKCSTHF EKVSPKYRHL LDDRMATIDI GVLLHQTPGG MLSNLINQLR DMGASDKLDA VFKALPQVRK EMGQVPLVTP TSQIVGIQAV NNVLFDTPQE RYKMISAQSK DLFYGLYGET PVPVDPEIQK KALKGYPRGE TPTTARPADV LEPEMEKNWK DMEGLAKDID DVLIYGMYPM TGKRFLNWKY GKEPVPKEVM PKTLEDCAKE ADLVKKAKAG LLVEKPTKVA PEKGPGLRTF SVFVDEEFFE VGVEQIGGAP AITSITPMVA PVAAPAAAPA AAPKPAAAPA AAPKPAAAPV EGGTKLEAPM PGMVIRYEVK EGDSVKEGDV VMILEAMKME NSITAPAAGV IKQICCKDGQ SVQKGDVLAV IG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660
PF00682: 26-296 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
PF02436: 320-485 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF00364: 593-660 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌
Sequence: MENKHLHGT SLIAKLQDDP KVKVDNPIKI GDLTFRDGHQ SLFATRGRTE DLLPIAEEMN KIGYWSMEVW GGATFDTMHR FLNEDPWERP RQLKKYLKDT PMMMLLRGQN LVGYRNYADD MAEAFVDRAC INGIDIFRTF DAVNDFRNFE TVIKPIKKHK KHFQGTICYS LTEPRMGGPV YNLDYYVKKA KQLENMGADT VCIKDMAGLI APYDAYYLVK ALKENVKVPI HLHSHFTSGM ADLALLKAIE AGVDIVDTCL APWAYRSSHP AIEPLVMTLR HTSRDTGFDL HQLAKCSTHF EKVSPKYRHL LDDRMATIDI GVLLHQTPGG MLSNLINQLR DMGASDKLDA VFKALPQVRK EMGQVPLVTP TSQIVGIQAV NNVLFDTPQE RYKMISAQSK DLFYGLYGET PVPVDPEIQK KALKGYPRGE TPTTARPADV LEPEMEKNWK DMEGLAKDID DVLIYGMYPM TGKRFLNWKY GKEPVPKEVM PKTLEDCAKE ADLVKKAKAG LLVEKPTKVA PEKGPGLRTF SVFVDEEFFE VGVEQIGGAP AITSITPMVA PVAAPAAAPA AAPKPAAAPA AAPKPAAAPV EGGTKLEAPM PGMVIRYEVK EGDSVKEGDV VMILEAMKME NSITAPAAGV IKQICCKDGQ SVQKGDVLAV IG HMM: 36-95 GHQ SLFATRGRTE DLLPIAEEMN KIGYWSMEVW GGATFDTMHR FLNEDPWERP RQLKKYL ALI: 181-241 LDYYVKKA KQLENMGADT VCIKDMAGLI APYDAYYLVK ALKENVKVPI HLHSHFTSGM ADL ENV: 175-262 GGPV YNLDYYVKKA KQLENMGADT VCIKDMAGLI APYDAYYLVK ALKENVKVPI HLHSHFTSGM ADLALLKAIE AGVDIVDTCL APWA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660
Sequence: MRQRTFLIL VAILVPVAFI AGWYASRGSG GTGGAGDRKL LYYVDPMNPS FRSPEPGTAP CGMPLEPVYA GGATPGGVGT TPPGAVTVRA DRLQLIGVAR EAVRSGTLRH TLRLVGTVAP DETRLFRVTA ATAGRIREMG AATTGSLVNK GEILGSYYSG ELLVPQQNFL RMFETYQNVQ KGGTNPYDNF QGGGQLATYV RNVDVARQAL LNLGMTAEQV EEVAATRQPA YLVQIRAPAA GIVTSRNVSL GQSFDARADL FTIADLSLVW VLADAFEGQE EHFKAGTRAI VMQPGAGRRF AAVVSGVPPR FEAATRTLKV RLDVVNPGLL LRPDMLVDVE LPVEIGPGLF VPKGAVIDSG TRRIVFVEQG EGVFVPRTVR AGRRLGERVE IVGGLMEGET IVTAGNFLLD SESRMRAAGA AVAGMALDPI CGMEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AAAAKAEGVK EVAAQERQPA NGIGTKAFHM EDPVCGMDVD PDEASRAGLI STFQGAPFVF CSPECKQEFD KDPRGVLSRP AGERSMPPAV SAPHEDGQHG MPPSMQEKTP PPAPQPEQMP MRAPARGDDE SHGAASAEPM RMQVDPVCGM RVDSLKARAK GLVSEYGGKT WFFCARVCKK AFDRDPQAVA AKAQGVKESA EQERRLPNAH ESMASRMEDP VCGMEVDPVE AREQGLLSEH AGKTWFFCAP ECKQAFDADP TVYPQVVR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
PF16576: 106-336 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF04945: 685-732 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
Sequence: MRQRTFLIL VAILVPVAFI AGWYASRGSG GTGGAGDRKL LYYVDPMNPS FRSPEPGTAP CGMPLEPVYA GGATPGGVGT TPPGAVTVRA DRLQLIGVAR EAVRSGTLRH TLRLVGTVAP DETRLFRVTA ATAGRIREMG AATTGSLVNK GEILGSYYSG ELLVPQQNFL RMFETYQNVQ KGGTNPYDNF QGGGQLATYV RNVDVARQAL LNLGMTAEQV EEVAATRQPA YLVQIRAPAA GIVTSRNVSL GQSFDARADL FTIADLSLVW VLADAFEGQE EHFKAGTRAI VMQPGAGRRF AAVVSGVPPR FEAATRTLKV RLDVVNPGLL LRPDMLVDVE LPVEIGPGLF VPKGAVIDSG TRRIVFVEQG EGVFVPRTVR AGRRLGERVE IVGGLMEGET IVTAGNFLLD SESRMRAAGA AVAGMALDPI CGMEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AAAAKAEGVK EVAAQERQPA NGIGTKAFHM EDPVCGMDVD PDEASRAGLI STFQGAPFVF CSPECKQEFD KDPRGVLSRP AGERSMPPAV SAPHEDGQHG MPPSMQEKTP PPAPQPEQMP MRAPARGDDE SHGAASAEPM RMQVDPVCGM RVDSLKARAK GLVSEYGGKT WFFCARVCKK AFDRDPQAVA AKAQGVKESA EQERRLPNAH ESMASRMEDP VCGMEVDPVE AREQGLLSEH AGKTWFFCAP ECKQAFDADP TVYPQVVR HMM: 396-470 GET IVTAGNFLLD SESRMRAAGA AVAGMALDPI CGMEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AA ALI: 421-497 AGMALDPI CGMEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AAAAKAEGVK EVAAQERQPA NGIGTKAFH ENV: 404-514 NFLLD SESRMRAAGA AVAGMALDPI CGMEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AAAAKAEGVK EVAAQERQPA NGIGTKAFHM EDPVCGMDVD PDEASR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MRQRTFLIL VAILVPVAFI AGWYASRGSG GTGGAGDRKL LYYVDPMNPS FRSPEPGTAP CGMPLEPVYA GGATPGGVGT TPPGAVTVRA DRLQLIGVAR EAVRSGTLRH TLRLVGTVAP DETRLFRVTA ATAGRIREMG AATTGSLVNK GEILGSYYSG ELLVPQQNFL RMFETYQNVQ KGGTNPYDNF QGGGQLATYV RNVDVARQAL LNLGMTAEQV EEVAATRQPA YLVQIRAPAA GIVTSRNVSL GQSFDARADL FTIADLSLVW VLADAFEGQE EHFKAGTRAI VMQPGAGRRF AAVVSGVPPR FEAATRTLKV RLDVVNPGLL LRPDMLVDVE LPVEIGPGLF VPKGAVIDSG TRRIVFVEQG EGVFVPRTVR AGRRLGERVE IVGGLMEGET IVTAGNFLLD SESRMRAAGA AVAGMALDPI CGMEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AAAAKAEGVK EVAAQERQPA NGIGTKAFHM EDPVCGMDVD PDEASRAGLI STFQGAPFVF CSPECKQEFD KDPRGVLSRP AGERSMPPAV SAPHEDGQHG MPPSMQEKTP PPAPQPEQMP MRAPARGDDE SHGAASAEPM RMQVDPVCGM RVDSLKARAK GLVSEYGGKT WFFCARVCKK AFDRDPQAVA AKAQGVKESA EQERRLPNAH ESMASRMEDP VCGMEVDPVE AREQGLLSEH AGKTWFFCAP ECKQAFDADP TVYPQVVR HMM: 413-446 MRAAGA AVAGMALDPI CGMEVDETRA RANGLVSE ALI: 627-660 AK GLVSEYGGKT WFFCARVCKK AFDRDPQAVA AK ENV: 606-671 EPM RMQVDPVCGM RVDSLKARAK GLVSEYGGKT WFFCARVCKK AFDRDPQAVA AKAQGVKESA EQE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MRQRTFLIL VAILVPVAFI AGWYASRGSG GTGGAGDRKL LYYVDPMNPS FRSPEPGTAP CGMPLEPVYA GGATPGGVGT TPPGAVTVRA DRLQLIGVAR EAVRSGTLRH TLRLVGTVAP DETRLFRVTA ATAGRIREMG AATTGSLVNK GEILGSYYSG ELLVPQQNFL RMFETYQNVQ KGGTNPYDNF QGGGQLATYV RNVDVARQAL LNLGMTAEQV EEVAATRQPA YLVQIRAPAA GIVTSRNVSL GQSFDARADL FTIADLSLVW VLADAFEGQE EHFKAGTRAI VMQPGAGRRF AAVVSGVPPR FEAATRTLKV RLDVVNPGLL LRPDMLVDVE LPVEIGPGLF VPKGAVIDSG TRRIVFVEQG EGVFVPRTVR AGRRLGERVE IVGGLMEGET IVTAGNFLLD SESRMRAAGA AVAGMALDPI CGMEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AAAAKAEGVK EVAAQERQPA NGIGTKAFHM EDPVCGMDVD PDEASRAGLI STFQGAPFVF CSPECKQEFD KDPRGVLSRP AGERSMPPAV SAPHEDGQHG MPPSMQEKTP PPAPQPEQMP MRAPARGDDE SHGAASAEPM RMQVDPVCGM RVDSLKARAK GLVSEYGGKT WFFCARVCKK AFDRDPQAVA AKAQGVKESA EQERRLPNAH ESMASRMEDP VCGMEVDPVE AREQGLLSEH AGKTWFFCAP ECKQAFDADP TVYPQVVR HMM: 390-445 VGGLMEGET IVTAGNFLLD SESRMRAAGA AVAGMALDPI CGMEVDETRA RANGLVS ALI: 676-733 NAH ESMASRMEDP VCGMEVDPVE AREQGLLSEH AGKTWFFCAP ECKQAFDADP TVYPQ ENV: 663-737 GVKESA EQERRLPNAH ESMASRMEDP VCGMEVDPVE AREQGLLSEH AGKTWFFCAP ECKQAFDADP TVYPQVVR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MRQRTFLIL VAILVPVAFI AGWYASRGSG GTGGAGDRKL LYYVDPMNPS FRSPEPGTAP CGMPLEPVYA GGATPGGVGT TPPGAVTVRA DRLQLIGVAR EAVRSGTLRH TLRLVGTVAP DETRLFRVTA ATAGRIREMG AATTGSLVNK GEILGSYYSG ELLVPQQNFL RMFETYQNVQ KGGTNPYDNF QGGGQLATYV RNVDVARQAL LNLGMTAEQV EEVAATRQPA YLVQIRAPAA GIVTSRNVSL GQSFDARADL FTIADLSLVW VLADAFEGQE EHFKAGTRAI VMQPGAGRRF AAVVSGVPPR FEAATRTLKV RLDVVNPGLL LRPDMLVDVE LPVEIGPGLF VPKGAVIDSG TRRIVFVEQG EGVFVPRTVR AGRRLGERVE IVGGLMEGET IVTAGNFLLD SESRMRAAGA AVAGMALDPI CGMEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AAAAKAEGVK EVAAQERQPA NGIGTKAFHM EDPVCGMDVD PDEASRAGLI STFQGAPFVF CSPECKQEFD KDPRGVLSRP AGERSMPPAV SAPHEDGQHG MPPSMQEKTP PPAPQPEQMP MRAPARGDDE SHGAASAEPM RMQVDPVCGM RVDSLKARAK GLVSEYGGKT WFFCARVCKK AFDRDPQAVA AKAQGVKESA EQERRLPNAH ESMASRMEDP VCGMEVDPVE AREQGLLSEH AGKTWFFCAP ECKQAFDADP TVYPQVVR HMM: 424-448 ALDPI CGMEVDETRA RANGLVSEYG ALI: 446-470 EYG GTTWFFCAPV CKQEFDSDPK AA ENV: 431-485 MEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AAAAKAEGVK EVAAQER Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MRQRTFLIL VAILVPVAFI AGWYASRGSG GTGGAGDRKL LYYVDPMNPS FRSPEPGTAP CGMPLEPVYA GGATPGGVGT TPPGAVTVRA DRLQLIGVAR EAVRSGTLRH TLRLVGTVAP DETRLFRVTA ATAGRIREMG AATTGSLVNK GEILGSYYSG ELLVPQQNFL RMFETYQNVQ KGGTNPYDNF QGGGQLATYV RNVDVARQAL LNLGMTAEQV EEVAATRQPA YLVQIRAPAA GIVTSRNVSL GQSFDARADL FTIADLSLVW VLADAFEGQE EHFKAGTRAI VMQPGAGRRF AAVVSGVPPR FEAATRTLKV RLDVVNPGLL LRPDMLVDVE LPVEIGPGLF VPKGAVIDSG TRRIVFVEQG EGVFVPRTVR AGRRLGERVE IVGGLMEGET IVTAGNFLLD SESRMRAAGA AVAGMALDPI CGMEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AAAAKAEGVK EVAAQERQPA NGIGTKAFHM EDPVCGMDVD PDEASRAGLI STFQGAPFVF CSPECKQEFD KDPRGVLSRP AGERSMPPAV SAPHEDGQHG MPPSMQEKTP PPAPQPEQMP MRAPARGDDE SHGAASAEPM RMQVDPVCGM RVDSLKARAK GLVSEYGGKT WFFCARVCKK AFDRDPQAVA AKAQGVKESA EQERRLPNAH ESMASRMEDP VCGMEVDPVE AREQGLLSEH AGKTWFFCAP ECKQAFDADP TVYPQVVR HMM: 423-447 MALDPI CGMEVDETRA RANGLVSEY ALI: 519-543 STFQGAPFVF CSPECKQEFD KDPRG ENV: 483-549 QERQPA NGIGTKAFHM EDPVCGMDVD PDEASRAGLI STFQGAPFVF CSPECKQEFD KDPRGVLSRP A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MRQRTFLIL VAILVPVAFI AGWYASRGSG GTGGAGDRKL LYYVDPMNPS FRSPEPGTAP CGMPLEPVYA GGATPGGVGT TPPGAVTVRA DRLQLIGVAR EAVRSGTLRH TLRLVGTVAP DETRLFRVTA ATAGRIREMG AATTGSLVNK GEILGSYYSG ELLVPQQNFL RMFETYQNVQ KGGTNPYDNF QGGGQLATYV RNVDVARQAL LNLGMTAEQV EEVAATRQPA YLVQIRAPAA GIVTSRNVSL GQSFDARADL FTIADLSLVW VLADAFEGQE EHFKAGTRAI VMQPGAGRRF AAVVSGVPPR FEAATRTLKV RLDVVNPGLL LRPDMLVDVE LPVEIGPGLF VPKGAVIDSG TRRIVFVEQG EGVFVPRTVR AGRRLGERVE IVGGLMEGET IVTAGNFLLD SESRMRAAGA AVAGMALDPI CGMEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AAAAKAEGVK EVAAQERQPA NGIGTKAFHM EDPVCGMDVD PDEASRAGLI STFQGAPFVF CSPECKQEFD KDPRGVLSRP AGERSMPPAV SAPHEDGQHG MPPSMQEKTP PPAPQPEQMP MRAPARGDDE SHGAASAEPM RMQVDPVCGM RVDSLKARAK GLVSEYGGKT WFFCARVCKK AFDRDPQAVA AKAQGVKESA EQERRLPNAH ESMASRMEDP VCGMEVDPVE AREQGLLSEH AGKTWFFCAP ECKQAFDADP TVYPQVVR HMM: 424-449 ALDPI CGMEVDETRA RANGLVSEYG G ALI: 633-658 EYGGKT WFFCARVCKK AFDRDPQAVA ENV: 622-671 SLKARAK GLVSEYGGKT WFFCARVCKK AFDRDPQAVA AKAQGVKESA EQE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MRQRTFLIL VAILVPVAFI AGWYASRGSG GTGGAGDRKL LYYVDPMNPS FRSPEPGTAP CGMPLEPVYA GGATPGGVGT TPPGAVTVRA DRLQLIGVAR EAVRSGTLRH TLRLVGTVAP DETRLFRVTA ATAGRIREMG AATTGSLVNK GEILGSYYSG ELLVPQQNFL RMFETYQNVQ KGGTNPYDNF QGGGQLATYV RNVDVARQAL LNLGMTAEQV EEVAATRQPA YLVQIRAPAA GIVTSRNVSL GQSFDARADL FTIADLSLVW VLADAFEGQE EHFKAGTRAI VMQPGAGRRF AAVVSGVPPR FEAATRTLKV RLDVVNPGLL LRPDMLVDVE LPVEIGPGLF VPKGAVIDSG TRRIVFVEQG EGVFVPRTVR AGRRLGERVE IVGGLMEGET IVTAGNFLLD SESRMRAAGA AVAGMALDPI CGMEVDETRA RANGLVSEYG GTTWFFCAPV CKQEFDSDPK AAAAKAEGVK EVAAQERQPA NGIGTKAFHM EDPVCGMDVD PDEASRAGLI STFQGAPFVF CSPECKQEFD KDPRGVLSRP AGERSMPPAV SAPHEDGQHG MPPSMQEKTP PPAPQPEQMP MRAPARGDDE SHGAASAEPM RMQVDPVCGM RVDSLKARAK GLVSEYGGKT WFFCARVCKK AFDRDPQAVA AKAQGVKESA EQERRLPNAH ESMASRMEDP VCGMEVDPVE AREQGLLSEH AGKTWFFCAP ECKQAFDADP TVYPQVVR HMM: 424-451 ALDPI CGMEVDETRA RANGLVSEYG GTT ALI: 707-734 EH AGKTWFFCAP ECKQAFDADP TVYPQV ENV: 663-736 GVKESA EQERRLPNAH ESMASRMEDP VCGMEVDPVE AREQGLLSEH AGKTWFFCAP ECKQAFDADP TVYPQVVR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MKRLLIVLV LALGLMLSGF AFAPEAADAG KAQTNCPVMG GKIDRTVFAD YQGKRVYFCC TGCVEDFRKD PDKYIRKLES EGVELEKTSD AK
10 20 30 40 50 60 70 80 90
PF04945: 48-74 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
Sequence: MKRLLIVLV LALGLMLSGF AFAPEAADAG KAQTNCPVMG GKIDRTVFAD YQGKRVYFCC TGCVEDFRKD PDKYIRKLES EGVELEKTSD AK HMM: 424-451 ALI: 48-75 D YQGKRVYFCC TGCVEDFRKD PDKYIRK ENV: 36-82 VMG GKIDRTVFAD YQGKRVYFCC TGCVEDFRKD PDKYIRKLES EGVE Position: 10 20 30 40 50 60 70 80 90
Sequence: MHFKLTEEQ ELVRAGVREF CQKYVEPIAE EVDMEPRFPM ENIKRLAEQD WCGIPYPTQY GGAGADYLTY TIVVEELSRA CAATGFTLEC QTSLASFPLF KFGTEEQKQK WLTPLCKGQI LGSFALTEPG AGTDVAAGST TAVLDGDSYV LNGTKMFISN APVAGVFIIF ASTDKSKGPK GLSAFIVPAD TSGIKPGEHL NKMGIRGALT SEVVLKNCRI PKGNLLGGEG QGFKIAMMTL DGGRIGIAAQ ALGIAQAALD ESIHYSKERV QFGKPISSFQ AIQWMLADMA TEVEASRFLT YHAAWCYDQG LPYSKEAAMA KLHAAETAAR QTNRAIQIHG GIGFIKGHKV ERLYRDAKIT EIYEGTSEVM RMVISGSILR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-117 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 121-217 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 228-376 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
Sequence: MHFKLTEEQ ELVRAGVREF CQKYVEPIAE EVDMEPRFPM ENIKRLAEQD WCGIPYPTQY GGAGADYLTY TIVVEELSRA CAATGFTLEC QTSLASFPLF KFGTEEQKQK WLTPLCKGQI LGSFALTEPG AGTDVAAGST TAVLDGDSYV LNGTKMFISN APVAGVFIIF ASTDKSKGPK GLSAFIVPAD TSGIKPGEHL NKMGIRGALT SEVVLKNCRI PKGNLLGGEG QGFKIAMMTL DGGRIGIAAQ ALGIAQAALD ESIHYSKERV QFGKPISSFQ AIQWMLADMA TEVEASRFLT YHAAWCYDQG LPYSKEAAMA KLHAAETAAR QTNRAIQIHG GIGFIKGHKV ERLYRDAKIT EIYEGTSEVM RMVISGSILR HMM: 59-288 GGAGADYLTY TIVVEELSRA CAATGFTLEC QTSLASFPLF KFGTEEQKQK WLTPLCKGQI LGSFALTEPG AGTDVAAGST TAVLDGDSYV LNGTKMFISN APVAGVFIIF ASTDKSKGPK GLSAFIVPAD TSGIKPGEHL NKMGIRGALT SEVVLKNCRI PKGNLLGGEG QGFKIAMMTL DGGRIGIAAQ ALGIAQAALD ESIHYSKERV QFGKPISSFQ AIQWMLADMA ALI: 52-276 IPYPTQY GGAGADYLTY TIVVEELSRA CAATGFTLEC QTSLASFPLF KFGTEEQKQK WLTPLCKGQI LGSFALTEPG AGTDVAAGST TAVLDGDSYV LNGTKMFISN APVAGVFIIF ASTDKSKGPK GLSAFIVPAD TSGIKPGEHL NKMGIRGALT SEVVLKNCRI PKGNLLGGEG QGFKIAMMTL DGGRIGIAAQ ALGIAQAALD ESIHYSKERV QFGKPISS ENV: 14-294 GVREF CQKYVEPIAE EVDMEPRFPM ENIKRLAEQD WCGIPYPTQY GGAGADYLTY TIVVEELSRA CAATGFTLEC QTSLASFPLF KFGTEEQKQK WLTPLCKGQI LGSFALTEPG AGTDVAAGST TAVLDGDSYV LNGTKMFISN APVAGVFIIF ASTDKSKGPK GLSAFIVPAD TSGIKPGEHL NKMGIRGALT SEVVLKNCRI PKGNLLGGEG QGFKIAMMTL DGGRIGIAAQ ALGIAQAALD ESIHYSKERV QFGKPISSFQ AIQWMLADMA TEVEAS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MDFQFTDEQ RMIKETVYKW AVNELGPLQE KIDDEDWFPP DFFKKCAEIG ILGITIDEKY GGLGGDVLMQ TLAVEQMSRI CPALGMTYGT HSNLCMNNIH RNASEALKEK YLPSMVAGEK IGALGLTEPN AGSDAMGLRT RAVRKGDKYI LNGTKMFITN GPVADVLLVY AKTDPERGAK GISAFIVEKE FPGYKVSRKL KKCGMRGSPT GELVFEDCEV PAENLVGEEN KGVNVVTSGL DIERIVLAGG SLGMAQQALD YSIRYSVERE QFGRPIASFQ MIQQKLADMY ARTEAAKLLV YKAAQVARNS PRGGKGTELT KLAAAGILFA AETATWVCDQ AVQIHGGYGY CLEFPVQKLW RDAKLYEIGA GTSEIRRLIV ARELTREEFA RKSSR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-217 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 228-383 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌
Sequence: MDFQFTDEQ RMIKETVYKW AVNELGPLQE KIDDEDWFPP DFFKKCAEIG ILGITIDEKY GGLGGDVLMQ TLAVEQMSRI CPALGMTYGT HSNLCMNNIH RNASEALKEK YLPSMVAGEK IGALGLTEPN AGSDAMGLRT RAVRKGDKYI LNGTKMFITN GPVADVLLVY AKTDPERGAK GISAFIVEKE FPGYKVSRKL KKCGMRGSPT GELVFEDCEV PAENLVGEEN KGVNVVTSGL DIERIVLAGG SLGMAQQALD YSIRYSVERE QFGRPIASFQ MIQQKLADMY ARTEAAKLLV YKAAQVARNS PRGGKGTELT KLAAAGILFA AETATWVCDQ AVQIHGGYGY CLEFPVQKLW RDAKLYEIGA GTSEIRRLIV ARELTREEFA RKSSR HMM: 55-298 DEKY GGLGGDVLMQ TLAVEQMSRI CPALGMTYGT HSNLCMNNIH RNASEALKEK YLPSMVAGEK IGALGLTEPN AGSDAMGLRT RAVRKGDKYI LNGTKMFITN GPVADVLLVY AKTDPERGAK GISAFIVEKE FPGYKVSRKL KKCGMRGSPT GELVFEDCEV PAENLVGEEN KGVNVVTSGL DIERIVLAGG SLGMAQQALD YSIRYSVERE QFGRPIASFQ MIQQKLADMY ARTEAAKLLV ALI: 48-290 G ILGITIDEKY GGLGGDVLMQ TLAVEQMSRI CPALGMTYGT HSNLCMNNIH RNASEALKEK YLPSMVAGEK IGALGLTEPN AGSDAMGLRT RAVRKGDKYI LNGTKMFITN GPVADVLLVY AKTDPERGAK GISAFIVEKE FPGYKVSRKL KKCGMRGSPT GELVFEDCEV PAENLVGEEN KGVNVVTSGL DIERIVLAGG SLGMAQQALD YSIRYSVERE QFGRPIASFQ MIQQKLADMY AR ENV: 43-367 KCAEIG ILGITIDEKY GGLGGDVLMQ TLAVEQMSRI CPALGMTYGT HSNLCMNNIH RNASEALKEK YLPSMVAGEK IGALGLTEPN AGSDAMGLRT RAVRKGDKYI LNGTKMFITN GPVADVLLVY AKTDPERGAK GISAFIVEKE FPGYKVSRKL KKCGMRGSPT GELVFEDCEV PAENLVGEEN KGVNVVTSGL DIERIVLAGG SLGMAQQALD YSIRYSVERE QFGRPIASFQ MIQQKLADMY ARTEAAKLLV YKAAQVARNS PRGGKGTELT KLAAAGILFA AETATWVCDQ AVQIHGGYGY CLEFPVQKLW RDAKLYEIG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390
Sequence: MPPDAFLER IFHGSIDPDV FQSFRVVQDE AKVDRLRKAY AAILDEYPAG ALEAAGAIPE RMLRRMGEIG LFGVTIPEEY GGLGFNVWEY MRLVEAMVKM DVSVAIASIA HCSIGVKGVQ LFGNDAQKRK YLVPAATGEM IFSYALTEPR IGSDAQHIET LAELSPDGSH YILNGQKTYI TNANYAGGLT VFARMDPRRP GFLGVFIVET GWEGVKVGKD MPKMGLKASS TAPVRFTNVR VPVENLLGKP GEGFKIAMTV LNYGRLGLGA ASVGMMERSL RDMMKRSSTR VQFQVPIRDF PLIQEKLVRA RVNAAVSKAM NDFAAHFLNA APRLNVAIET SHCKLFGTTR AWDTLYDALQ VAGGSGYLST QPYEKRMRDF RVATVFEGTT EIHSIYPALF LIRKTAKDAL RGGRRTAALT FCLKALAARI DWELGFDNRI MRRAWRLAGA NARTISRMIP ALYLLYRDRL PEKEYLLRRI STLSLYLFGL VALLAGMSAR SGSGPYGEED LRVLAHFTEE AALARKASRR LFDSRKEILD GLICRDLFRG WKDERG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550
PF02771: 37-138 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 141-238 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 249-392 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
Sequence: MPPDAFLER IFHGSIDPDV FQSFRVVQDE AKVDRLRKAY AAILDEYPAG ALEAAGAIPE RMLRRMGEIG LFGVTIPEEY GGLGFNVWEY MRLVEAMVKM DVSVAIASIA HCSIGVKGVQ LFGNDAQKRK YLVPAATGEM IFSYALTEPR IGSDAQHIET LAELSPDGSH YILNGQKTYI TNANYAGGLT VFARMDPRRP GFLGVFIVET GWEGVKVGKD MPKMGLKASS TAPVRFTNVR VPVENLLGKP GEGFKIAMTV LNYGRLGLGA ASVGMMERSL RDMMKRSSTR VQFQVPIRDF PLIQEKLVRA RVNAAVSKAM NDFAAHFLNA APRLNVAIET SHCKLFGTTR AWDTLYDALQ VAGGSGYLST QPYEKRMRDF RVATVFEGTT EIHSIYPALF LIRKTAKDAL RGGRRTAALT FCLKALAARI DWELGFDNRI MRRAWRLAGA NARTISRMIP ALYLLYRDRL PEKEYLLRRI STLSLYLFGL VALLAGMSAR SGSGPYGEED LRVLAHFTEE AALARKASRR LFDSRKEILD GLICRDLFRG WKDERG HMM: 51-235 EAAGAIPE RMLRRMGEIG LFGVTIPEEY GGLGFNVWEY MRLVEAMVKM DVSVAIASIA HCSIGVKGVQ LFGNDAQKRK YLVPAATGEM IFSYALTEPR IGSDAQHIET LAELSPDGSH YILNGQKTYI TNANYAGGLT VFARMDPRRP GFLGVFIVET GWEGVKVGKD MPKMGLKASS TAPVRFT ALI: 64-250 MGEIG LFGVTIPEEY GGLGFNVWEY MRLVEAMVKM DVSVAIASIA HCSIGVKGVQ LFGNDAQKRK YLVPAATGEM IFSYALTEPR IGSDAQHIET LAELSPDGSH YILNGQKTYI TNANYAGGLT VFARMDPRRP GFLGVFIVET GWEGVKVGKD MPKMGLKASS TAPVRFTNVR VPVENLLGKP GE ENV: 22-272 FRVVQDE AKVDRLRKAY AAILDEYPAG ALEAAGAIPE RMLRRMGEIG LFGVTIPEEY GGLGFNVWEY MRLVEAMVKM DVSVAIASIA HCSIGVKGVQ LFGNDAQKRK YLVPAATGEM IFSYALTEPR IGSDAQHIET LAELSPDGSH YILNGQKTYI TNANYAGGLT VFARMDPRRP GFLGVFIVET GWEGVKVGKD MPKMGLKASS TAPVRFTNVR VPVENLLGKP GEGFKIAMTV LNYGRLGLGA ASVG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550
Sequence: MDFRFSERE EMLRKFVREF AENEIPPKME SMETNGKFPI ELMPFMAQIG ITGIITPTQY EGVGLGYVAR TIVLEELGRV CAAVPMAMQV HHMACAALAD FGNETQKKKY LPRLARGDTM GCVAVTEPGG GSDVAGTKTT ADLKGDKYII NGRKCFITNT HTSDFWVVIA RTGEGAKGLS AFVVDKNAPG ARVGREENKF GMRGANTGEL VFNDCEVPRE NLLGQEGGGV GVAMKTVSET GRTGMAAVAL GILTCAYEEA AKFAQERVLY GKPIATLQAI QFYMAEIFAQ LEIARLLCYR ASWMKDNNLR FDTESALAKW YTCEAAATAA KRAVEIHGSY GIMKEYTVQR LLRDAMVTIP AGGTGEIGKL VLGRAALAPF KK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-117 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 120-214 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF00441: 225-375 ◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
Sequence: MDFRFSERE EMLRKFVREF AENEIPPKME SMETNGKFPI ELMPFMAQIG ITGIITPTQY EGVGLGYVAR TIVLEELGRV CAAVPMAMQV HHMACAALAD FGNETQKKKY LPRLARGDTM GCVAVTEPGG GSDVAGTKTT ADLKGDKYII NGRKCFITNT HTSDFWVVIA RTGEGAKGLS AFVVDKNAPG ARVGREENKF GMRGANTGEL VFNDCEVPRE NLLGQEGGGV GVAMKTVSET GRTGMAAVAL GILTCAYEEA AKFAQERVLY GKPIATLQAI QFYMAEIFAQ LEIARLLCYR ASWMKDNNLR FDTESALAKW YTCEAAATAA KRAVEIHGSY GIMKEYTVQR LLRDAMVTIP AGGTGEIGKL VLGRAALAPF KK HMM: 55-277 PTQY EGVGLGYVAR TIVLEELGRV CAAVPMAMQV HHMACAALAD FGNETQKKKY LPRLARGDTM GCVAVTEPGG GSDVAGTKTT ADLKGDKYII NGRKCFITNT HTSDFWVVIA RTGEGAKGLS AFVVDKNAPG ARVGREENKF GMRGANTGEL VFNDCEVPRE NLLGQEGGGV GVAMKTVSET GRTGMAAVAL GILTCAYEEA AKFAQERVLY GKPIATLQA ALI: 48-263 G ITGIITPTQY EGVGLGYVAR TIVLEELGRV CAAVPMAMQV HHMACAALAD FGNETQKKKY LPRLARGDTM GCVAVTEPGG GSDVAGTKTT ADLKGDKYII NGRKCFITNT HTSDFWVVIA RTGEGAKGLS AFVVDKNAPG ARVGREENKF GMRGANTGEL VFNDCEVPRE NLLGQEGGGV GVAMKTVSET GRTGMAAVAL GILTCAYEEA AKFAQ ENV: 16-357 REF AENEIPPKME SMETNGKFPI ELMPFMAQIG ITGIITPTQY EGVGLGYVAR TIVLEELGRV CAAVPMAMQV HHMACAALAD FGNETQKKKY LPRLARGDTM GCVAVTEPGG GSDVAGTKTT ADLKGDKYII NGRKCFITNT HTSDFWVVIA RTGEGAKGLS AFVVDKNAPG ARVGREENKF GMRGANTGEL VFNDCEVPRE NLLGQEGGGV GVAMKTVSET GRTGMAAVAL GILTCAYEEA AKFAQERVLY GKPIATLQAI QFYMAEIFAQ LEIARLLCYR ASWMKDNNLR FDTESALAKW YTCEAAATAA KRAVEIHGSY GIMKEYTVQR LLRDAMVTI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDYFLTEEQ VMIQELAGQI AREKIRPVRA QLDEQEEFPW EIMKICAQAD LFGLYIPEEY GGLGGGILEN CLAIEKIAEA CIGIATSFAA SGLGAYPILL FGSEALKRAY LPDIASGKRL AAFGLTESGA GSDVSGIQTT AVRDGDHYVL NGAKQWITNG GEAEIYSVLA ITDRSKGPRG ASFFVVEKDD PGFSFGKKEK KLGIRASATR ELVFQDCRIP KERLIGREGT GFIVAMKTFD KSRPGIGALG VGLSQGALDI SVEYARKRMQ FGKPIISFQA IQHKLADMAI KTEAARALIY AAARYMDTDP PDSSKVAAMC KVFAGDAALY AATEAVQILG GYGYMQDYPV EKMMRDAKIL QIYEGTNEIQ RNIIGQELNK EYSRLKESFF
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-117 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 120-216 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 227-376 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
Sequence: MDYFLTEEQ VMIQELAGQI AREKIRPVRA QLDEQEEFPW EIMKICAQAD LFGLYIPEEY GGLGGGILEN CLAIEKIAEA CIGIATSFAA SGLGAYPILL FGSEALKRAY LPDIASGKRL AAFGLTESGA GSDVSGIQTT AVRDGDHYVL NGAKQWITNG GEAEIYSVLA ITDRSKGPRG ASFFVVEKDD PGFSFGKKEK KLGIRASATR ELVFQDCRIP KERLIGREGT GFIVAMKTFD KSRPGIGALG VGLSQGALDI SVEYARKRMQ FGKPIISFQA IQHKLADMAI KTEAARALIY AAARYMDTDP PDSSKVAAMC KVFAGDAALY AATEAVQILG GYGYMQDYPV EKMMRDAKIL QIYEGTNEIQ RNIIGQELNK EYSRLKESFF HMM: 55-324 PEEY GGLGGGILEN CLAIEKIAEA CIGIATSFAA SGLGAYPILL FGSEALKRAY LPDIASGKRL AAFGLTESGA GSDVSGIQTT AVRDGDHYVL NGAKQWITNG GEAEIYSVLA ITDRSKGPRG ASFFVVEKDD PGFSFGKKEK KLGIRASATR ELVFQDCRIP KERLIGREGT GFIVAMKTFD KSRPGIGALG VGLSQGALDI SVEYARKRMQ FGKPIISFQA IQHKLADMAI KTEAARALIY AAARYMDTDP PDSSKVAAMC KVFAGD ALI: 48-306 D LFGLYIPEEY GGLGGGILEN CLAIEKIAEA CIGIATSFAA SGLGAYPILL FGSEALKRAY LPDIASGKRL AAFGLTESGA GSDVSGIQTT AVRDGDHYVL NGAKQWITNG GEAEIYSVLA ITDRSKGPRG ASFFVVEKDD PGFSFGKKEK KLGIRASATR ELVFQDCRIP KERLIGREGT GFIVAMKTFD KSRPGIGALG VGLSQGALDI SVEYARKRMQ FGKPIISFQA IQHKLADMAI KTEAARALIY AAARYMDT ENV: 40-382 IMKICAQAD LFGLYIPEEY GGLGGGILEN CLAIEKIAEA CIGIATSFAA SGLGAYPILL FGSEALKRAY LPDIASGKRL AAFGLTESGA GSDVSGIQTT AVRDGDHYVL NGAKQWITNG GEAEIYSVLA ITDRSKGPRG ASFFVVEKDD PGFSFGKKEK KLGIRASATR ELVFQDCRIP KERLIGREGT GFIVAMKTFD KSRPGIGALG VGLSQGALDI SVEYARKRMQ FGKPIISFQA IQHKLADMAI KTEAARALIY AAARYMDTDP PDSSKVAAMC KVFAGDAALY AATEAVQILG GYGYMQDYPV EKMMRDAKIL QIYEGTNEIQ RNIIGQELNK EYSR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MRLLVDDRD QKFVLYEQLR IDELSHFPLF SEFSRDLSDM ILEQAEKLAE NEFLPVNRTG DLEGCRFEGG MVKVPESFHR AYARYREGGW LSLSDSTDYG GQGMPFVLAN ACVEYFAAAN WALLMYPGLT HGSSRLLEKY GTSELKETYL YKMYAGEWSG TMCLTEPDAG SDVGNLRTRA KRLPDGTYSI RGQKIFISCG MHDLTDNIIH MVLARIEGAP KGVRGISIFA VPRLRVTETG ELAENDVVCT GLEHKLGIHG AATCTMNFGE NERCVGYLLG KENTGMRIMF EMMNEARLFT GLQGLGHASA AYLHALNYAK ERRQGALIQH MKHPETPRVP IIRHPDVRRM LMFMKSSTEG LRALMHLGGY CIDRSRAAEA EEEKELFQGY ADLLIPLCKS VGSDLGFRVC ETAIQVYGGY GYVTEYPVEQ FLRDCKIASI YEGTNGIQAL DLVGRKLTYR RGLLVKNALN AIENILSRIR RNFSLRDLVR IYEEAQESTV QVTKFFALKG MTDEFESPLL YAKPYLDLCG DVAIGFLLLW QANIADQRLQ EIYRDHNATD QPSRTRVVNE NRSAAFYFGK IASARFFINQ VLTQAGGRAR AIMNNDRSAL EIPDDGFALG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
PF12418: 4-33 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF02771: 37-156 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
PF02770: 160-267 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 281-451 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
PF12806: 470-612 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MRLLVDDRD QKFVLYEQLR IDELSHFPLF SEFSRDLSDM ILEQAEKLAE NEFLPVNRTG DLEGCRFEGG MVKVPESFHR AYARYREGGW LSLSDSTDYG GQGMPFVLAN ACVEYFAAAN WALLMYPGLT HGSSRLLEKY GTSELKETYL YKMYAGEWSG TMCLTEPDAG SDVGNLRTRA KRLPDGTYSI RGQKIFISCG MHDLTDNIIH MVLARIEGAP KGVRGISIFA VPRLRVTETG ELAENDVVCT GLEHKLGIHG AATCTMNFGE NERCVGYLLG KENTGMRIMF EMMNEARLFT GLQGLGHASA AYLHALNYAK ERRQGALIQH MKHPETPRVP IIRHPDVRRM LMFMKSSTEG LRALMHLGGY CIDRSRAAEA EEEKELFQGY ADLLIPLCKS VGSDLGFRVC ETAIQVYGGY GYVTEYPVEQ FLRDCKIASI YEGTNGIQAL DLVGRKLTYR RGLLVKNALN AIENILSRIR RNFSLRDLVR IYEEAQESTV QVTKFFALKG MTDEFESPLL YAKPYLDLCG DVAIGFLLLW QANIADQRLQ EIYRDHNATD QPSRTRVVNE NRSAAFYFGK IASARFFINQ VLTQAGGRAR AIMNNDRSAL EIPDDGFALG HMM: 52-165 LPVNRTG DLEGCRFEGG MVKVPESFHR AYARYREGGW LSLSDSTDYG GQGMPFVLAN ACVEYFAAAN WALLMYPGLT HGSSRLLEKY GTSELKETYL YKMYAGEWSG TMCLTEP ALI: 84-199 REGGW LSLSDSTDYG GQGMPFVLAN ACVEYFAAAN WALLMYPGLT HGSSRLLEKY GTSELKETYL YKMYAGEWSG TMCLTEPDAG SDVGNLRTRA KRLPDGTYSI RGQKIFISCG M ENV: 72-312 VPESFHR AYARYREGGW LSLSDSTDYG GQGMPFVLAN ACVEYFAAAN WALLMYPGLT HGSSRLLEKY GTSELKETYL YKMYAGEWSG TMCLTEPDAG SDVGNLRTRA KRLPDGTYSI RGQKIFISCG MHDLTDNIIH MVLARIEGAP KGVRGISIFA VPRLRVTETG ELAENDVVCT GLEHKLGIHG AATCTMNFGE NERCVGYLLG KENTGMRIMF EMMNEARLFT GLQGLGHASA AYLH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MRLLVDDRD QKFVLYEQLR IDELSHFPLF SEFSRDLSDM ILEQAEKLAE NEFLPVNRTG DLEGCRFEGG MVKVPESFHR AYARYREGGW LSLSDSTDYG GQGMPFVLAN ACVEYFAAAN WALLMYPGLT HGSSRLLEKY GTSELKETYL YKMYAGEWSG TMCLTEPDAG SDVGNLRTRA KRLPDGTYSI RGQKIFISCG MHDLTDNIIH MVLARIEGAP KGVRGISIFA VPRLRVTETG ELAENDVVCT GLEHKLGIHG AATCTMNFGE NERCVGYLLG KENTGMRIMF EMMNEARLFT GLQGLGHASA AYLHALNYAK ERRQGALIQH MKHPETPRVP IIRHPDVRRM LMFMKSSTEG LRALMHLGGY CIDRSRAAEA EEEKELFQGY ADLLIPLCKS VGSDLGFRVC ETAIQVYGGY GYVTEYPVEQ FLRDCKIASI YEGTNGIQAL DLVGRKLTYR RGLLVKNALN AIENILSRIR RNFSLRDLVR IYEEAQESTV QVTKFFALKG MTDEFESPLL YAKPYLDLCG DVAIGFLLLW QANIADQRLQ EIYRDHNATD QPSRTRVVNE NRSAAFYFGK IASARFFINQ VLTQAGGRAR AIMNNDRSAL EIPDDGFALG HMM: 348-391 M LMFMKSSTEG LRALMHLGGY CIDRSRAAEA EEEKELFQGY ADL ALI: 397-440 KS VGSDLGFRVC ETAIQVYGGY GYVTEYPVEQ FLRDCKIASI YE ENV: 372-443 RSRAAEA EEEKELFQGY ADLLIPLCKS VGSDLGFRVC ETAIQVYGGY GYVTEYPVEQ FLRDCKIASI YEGTN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MRNFIEQMR SQGLVTDVHE PVSSRFDAPK RAFSTDKLLF FHNLDGKKAV MNLVASREAL AVALGVPSGE LVPKLAKCRY NGTLKDAGTL PLRPVNLDEI PIMENYPKEG GRYLNSGVVF SRYEGIENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL AQGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEGEFVRA VWED
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
PF01977: 4-374 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MRNFIEQMR SQGLVTDVHE PVSSRFDAPK RAFSTDKLLF FHNLDGKKAV MNLVASREAL AVALGVPSGE LVPKLAKCRY NGTLKDAGTL PLRPVNLDEI PIMENYPKEG GRYLNSGVVF SRYEGIENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL AQGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEGEFVRA VWED HMM: 187-418 SM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEGEFVRA VWED ALI: 160-381 QGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPS ENV: 92-384 PVNLDEI PIMENYPKEG GRYLNSGVVF SRYEGIENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL AQGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MRNFIEQMR SQGLVTDVHE PVSSRFDAPK RAFSTDKLLF FHNLDGKKAV MNLVASREAL AVALGVPSGE LVPKLAKCRY NGTLKDAGTL PLRPVNLDEI PIMENYPKEG GRYLNSGVVF SRYEGIENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL AQGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEGEFVRA VWED HMM: 132-452 MLKAGKD RLVARLVEGR HTHTLHKKAL AQGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEGEFVRA VWED ALI: 95-404 LDEI PIMENYPKEG GRYLNSGVVF SRYEGIENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL AQGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEGE ENV: 65-412 PSGE LVPKLAKCRY NGTLKDAGTL PLRPVNLDEI PIMENYPKEG GRYLNSGVVF SRYEGIENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL AQGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEGEFVRA VWED Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MRNFIEQMR SQGLVTDVHE PVSSRFDAPK RAFSTDKLLF FHNLDGKKAV MNLVASREAL AVALGVPSGE LVPKLAKCRY NGTLKDAGTL PLRPVNLDEI PIMENYPKEG GRYLNSGVVF SRYEGIENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL AQGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEGEFVRA VWED HMM: 119-407 SRYEGIENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL AQGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEGEFVR ALI: 95-372 LDEI PIMENYPKEG GRYLNSGVVF SRYEGIENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL AQGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPG ENV: 86-391 GTL PLRPVNLDEI PIMENYPKEG GRYLNSGVVF SRYEGIENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL AQGERLPVAV VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEIPVYTLPN GVRVPDAEII LEGYIGSETA VEGPYVDITR TYDPERIQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AQVTGVTDVV LTKGGCGYLH GVVQIRKRTE GDGKNAIMAA FAAHTSLKHV VIVDEDIDPA NLSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF04879: 0-55 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00384: 57-483 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF01568: 570-677 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 103-312 NEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGN ALI: 35-238 PVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC ENV: 5-240 TTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 387-469 PG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG E ALI: 242-328 DDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN ENV: 238-338 C NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 609-686 AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK ALI: 412-487 HALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYG ENV: 407-513 LT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 838-918 ALI: 568-650 Y PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HY ENV: 556-656 PFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAAN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 103-309 NEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM L ALI: 38-238 E GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC ENV: 5-243 TTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 395-465 IMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQD ALI: 254-324 SLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALR ENV: 241-341 FDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 611-679 KLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK I ALI: 417-483 LD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAK ENV: 391-491 KCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 820-901 ALI: 567-650 EY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HY ENV: 556-659 PFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL T Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 127-328 RL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN ALI: 43-238 PKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC ENV: 7-240 CP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 402-482 ISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAA ALI: 242-324 DDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALR ENV: 239-337 NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 566-703 NEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK ALI: 349-489 IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA Q ENV: 341-501 VYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HQFINSPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFRSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKFI YADPRYTPTG KQADLYLQFR SGTDVALMNG MMQEIIRNGW ENKEFIQNRC NGFDDLKKEV MKDDYSLENV SKITGVPAEK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DAWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETTEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQDPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FKEMATLTPS YGGMTYERLN RPEALHWPCP AQDHPGTPIL HGEKFGMPDG KGLMTGIPFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 840-920 ALI: 567-648 EY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF ENV: 556-655 PFK WPQEVPDNEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTDD AKKLGVVDKE KVKAKTRRGE ITITARVTPD IMPGVVFIPF HYVECAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF04879: 7-62 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF00384: 64-485 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF01568: 571-677 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 103-312 GLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGN ALI: 42-249 PINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR V ENV: 27-258 VN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 390-471 EEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQ ALI: 256-337 KKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQ ENV: 249-368 VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 606-684 NVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGG ALI: 411-487 LVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMG ENV: 408-508 D SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 837-915 ALI: 568-647 E YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYM ENV: 559-655 RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 99-310 HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SM ALI: 41-250 SPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VN ENV: 20-262 GCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 434-463 QYADV ILPGACFAEK DGTFTSGERR INRVR ALI: 300-329 LTTGTDNVR SMGNLALLTG NVGREGVGVN P ENV: 257-366 KT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 604-678 QINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS ALI: 412-484 VKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAA ENV: 398-490 L GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 821-924 ALI: 569-666 YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPM ENV: 562-679 AEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS I Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 127-328 GF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN ALI: 50-249 PKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR V ENV: 22-253 TLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 406-480 YPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI IS ALI: 257-329 KT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN P ENV: 250-338 NGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 625-701 SRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN ALI: 415-489 QFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL K ENV: 401-500 NPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENTELMK YVATTCPYCG VGCTLNLVVN NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LVKKDGKFVE ASWDEALDLV AKNLKAIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARIGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNSD LILIWGSNAV EAHPLAGRRI AQAKKKGIPI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGLEDLKKT VENYADAEAI HGVPLDVVKD MAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA DNRAKMEKAW GVTDLPDWYG ATLVEQIKQC GEEIKGMYIL GLNPAVTYPD SNLVKAQFQK LDFLVIQDIF FTESCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGL KGFELPTAKD VWDDMRAVTP SMFGATYEKL EKPESICWPC PTEEHPGTPI LHREKFGTAD GKGNLFGIEY RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK MPELKHCAIS IEKFGGN HMM: 840-920 ALI: 568-647 E YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYM ENV: 559-668 RPPAEVADAE YPFTLMTGRL IFHYHSRSQT GRAADMHREV PESYAQINVE DAKRLGIKNG EYIKLKSRRG ETKTLARVTD EVAPGVVYMT MHFPEGVNNL TNTALDPMSK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF04879: 3-56 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00384: 59-486 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
PF01568: 573-679 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 73-311 EATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QML ALI: 13-239 GTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK R ENV: 3-242 KYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 387-467 DK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQD ALI: 244-325 DELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNAL ENV: 239-339 RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG C Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 609-688 GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA ALI: 414-491 HALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQ ENV: 408-519 D LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER L Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 838-918 ALI: 570-652 YPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHY ENV: 558-658 P FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 70-309 KFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL Q ALI: 14-240 TGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RC ENV: 4-245 YVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 395-466 LYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQ ALI: 256-327 SLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRG ENV: 244-367 DELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 611-680 AKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VR ALI: 419-486 LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKM ENV: 396-493 YIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 820-899 ALI: 569-649 EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI P ENV: 558-660 P FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 126-328 HCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ ALI: 44-240 CPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RC ENV: 8-243 T CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 402-482 PMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASI ALI: 244-326 DELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALR ENV: 241-339 NGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG C Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 567-703 DE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA ALI: 352-491 DEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQ ENV: 340-494 LPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFVNAPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYNPDECMCL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLFLQ FRSGTDVCLM NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDEYSLE NVSSVTGVPV DKIKTAAEWF AKSGASAILY SMGITQHTTG VDNVKSCGNL QMLTGNLGRA GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADGWKFPDG IAKGENGYEV TTLMNVLTDK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAEKMGY GAQFPWKTSE EVFNEMASFT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHGEKFGMP DGKGLMTGIP FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAAN VLTINALDPI AKIPESKACA VRVEKIQEA HMM: 841-919 ALI: 570-649 YPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI P ENV: 559-657 FKWPQEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAKKLGIAD KEMVKAKTRR GEITITARVT DDIKPGVMFI PFHYVECAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF04879: 3-57 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00384: 59-486 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
PF01568: 573-679 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 75-311 SWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QML ALI: 16-239 CSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK R ENV: 4-243 YVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 387-469 DK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP P ALI: 244-330 DELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NN ENV: 240-341 CNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 609-684 EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKI ALI: 414-487 HALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMG ENV: 401-517 NPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 836-918 ALI: 568-652 A EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHF ENV: 556-658 AIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 70-309 KFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI Q ALI: 14-240 TGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RC ENV: 4-255 YVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 395-465 MYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKA ALI: 256-326 SLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALR ENV: 244-344 DELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 611-679 AKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA I ALI: 419-485 LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKA ENV: 403-494 MISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 815-899 ALI: 564-649 ERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI P ENV: 552-662 GLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 125-327 DHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRG ALI: 43-239 VCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK R ENV: 8-242 T CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 402-482 PMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEI ALI: 244-326 DELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALR ENV: 241-341 NGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 554-700 MTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA ALI: 345-488 TGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY ENV: 330-515 NVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSF NLVVKDGKVV GTAPYHRSPV NEGKVCPKGT YAHEFINSPD RLTKPLIKKD GKFVEASWEE AIKLIADKFK SYKPDECAVL SSARVSNEEN YAMMKFARGV LKTRHIDHCA RLCHASTVAG LANIFGSGAM TNSIPDIAES KCVFVIGSNT FENHPLIGRQ IMKAKSNGAK VVYVDPRKTP TGKQADLFLQ FYSGTDVCLL NGMMQEIIKN GWENKEFIEK RCNGFDELKK EVMKDDYSLE NVSSVTGVPV DDIKTAAEWF SKSGASTILY SMGITQHTTG VDNVKSVGNI QMLTGNLGRP GTGVNALRGQ NNVQGACDMG ALPVVFTGYQ KVIDEAAHKK FADAWKFPDG IAEGKNGYEV TVMMDVLTDK PGELKCMYIM GENPMISDPD LTHVEHALKS LEFLVVQDIF MNETGVLADV VLPSCCYAEK DGTQTSTERR VQMWRKAQDP PGEAKLDWVI ISEIAKAMGY GEQFAWKSAE EIFTEMAALT PSYAGMDYVR LNRPEALHWP CPTKEHPGTP ILHIEKFGMP DGKGLMTAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECAAN MLTINALDPI AKIPESKACA IKVEKIQEA HMM: 839-918 ALI: 568-648 A EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI ENV: 555-656 TAIP FKYQQERPDA EYPILLTTGR CIWHWHTGTM TRRSESLERE EPTGWIEMHP EDAKALGVKN NEMVKAISRR GEITIKARIT DTIKKGVMFI PFHFVECA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
PF04879: 21-76 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00384: 78-500 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
PF01568: 585-691 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 104-312 KKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGIT ALI: 57-263 IN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERV ENV: 39-266 LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 387-470 LP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GE ALI: 267-350 EE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NV ENV: 263-381 VNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 606-685 AAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPE ALI: 425-502 LVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGL ENV: 422-525 DSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 837-894 ALI: 582-640 EYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SR ENV: 573-667 RPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 100-310 DLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LG ALI: 56-264 PIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVN ENV: 16-276 SDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 399-463 IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKD ALI: 279-343 AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNP ENV: 264-380 NGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 601-680 QTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PM ALI: 424-500 NLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KM ENV: 403-506 GNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 820-901 ALI: 582-662 EYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMT ENV: 575-691 PAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 127-349 VN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN N ALI: 64-284 PKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHG ENV: 58-285 N DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 402-481 CGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVN ALI: 267-344 EE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPL ENV: 263-355 VNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 624-701 AKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N ALI: 428-503 A QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLK ENV: 401-513 QCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MDLFGLFHP ENSGERMSDS NLIKYVQTTC PYCGVGCTLN LVVKNEKVVG VEPYKRSPIN DGKLCPKGLT CWEHVHSPDR LTTPLIKKDG KFVEASWDEA LDLVAKKLKE TSDKYGPKGL GFQTSCRTVN EDCYIFQKFA RVGFKTNNVD NCARICHGPS VAGLSLSFGS GAATNGFEDA LNSDFILVWG SNALEAHPLA GRRMVQAKLK GIPIYAVDPR LSTTAKIADK WIQFNPSTHI ALANSMMYWI IKAGKHDKKF IEERVNGFEE LKAMVEKYAD AEDIHGVPLE TVKDLAYKYA SAKNAVIIYC LGITELTTGT DNVRSMGNLA LLTGNVGRPG VGVNPLRGQN NVQGACDMGA YPNVYSGYQK CEVADNRAKM EKAWGTSGLP DWYGATLVEQ IKQCGNEIKA MYVLGLNPVV TYPDSNLVKA QFQKLDFLVI QDIFFTESCQ YADVILPGAC FAEKDGTFTS GERRINRVRK AVNPPGKAKE DIWIIAELAK KMGLKGFELP TAKSVWDDMR NCTPNMFGAT YEKLEKPESI VWPCPTEDHP GTPILHIGKF STADGKGNLF GIEYRPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLTNTALD PMSKMPELKH CAVKVEKMGG N HMM: 840-916 ALI: 582-659 EYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV L ENV: 573-673 RPPAEV ADAEYPFTMM TGRLIFHYHS RSQTDRSAAL HYEVPASYVQ INHEDAKRLG IGQHEKILIS SRRGKTETVA HVTDEIGPGV LYMTMHFNEG VNNLT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
PF04879: 4-55 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00384: 58-484 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
PF01568: 571-674 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 96-313 VLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGN ALI: 31-240 PNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TR ENV: 7-242 IC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 387-467 RQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINP ALI: 243-324 ESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNAL ENV: 239-338 TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 610-683 ASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAG ALI: 414-485 AIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVM ENV: 397-492 VG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 834-915 ALI: 564-647 IPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFM ENV: 551-654 GVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 207-310 QF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM ML ALI: 137-240 GL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TR ENV: 8-246 C PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 393-465 ALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAI ALI: 253-325 RYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALR ENV: 240-339 REFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC L Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 609-680 DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IE ALI: 416-485 QNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVM ENV: 386-491 ARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 814-898 ALI: 561-647 PSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFM ENV: 541-661 NDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 223-329 EIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN N ALI: 134-240 TMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TR ENV: 40-242 GKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 402-482 LVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIA ALI: 243-325 ESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALR ENV: 239-334 TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGAC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 604-699 EIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S ALI: 395-486 FLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMG ENV: 382-492 QRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MISQIPTIC PYCGTGCSVN LIVQDGKVVG TNPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLVRKGG VFVETDWETV YQLIAQKFKS YTPDEIGVLA SARCTNEDNY VLMKFARGVL KTNNLDHCAR LCHEATMTGL TLSFGTGAMT NSIPDIGESE CVFCLGSNTF EQHPLIGRQI VRAQAAGGKF IYADPRYTPT AIQSDLFLQF FSGSDVAVLN CIMGEIIRNG WEDKEFIASR TREFESLKKV VLQSRYSPQN VSLLTGVSKE DLLLAAQWIG TSASCTVLYA MGLSQQSGGI NNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPGFFPGYQP VTDSLIHRKI GRIWKFPDGI CPPKEGLNIT NIFQRAGARQ NGIKALFLVG ENPLVTEPDQ NTTLHAIQNV EFLVVSDIFF TKTCEYAHIV LPAACFAEKD GTATNTERRV QHLSKAINPL GEAKPDWEII TDIARVMGFE KQFPYHSPEE IFGEITEVCE PYHGMTYVRI RHPDGICWPC PFDDHAGTPI LYNDRFYHPD GKGVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIFDSALNRL IGLPDDVQAG ISEYKPICVA IEPAGEEEEG S HMM: 832-913 ALI: 559-642 KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKE ENV: 551-651 GVFCPVEW KEPSEIPGKE FPFRLTSGRI IWHWHAGAMT RRSKNLADEV NEAYIEIHPS DASSARIVDG DMVQVRSRKG RLSCRARVVS DIKEGMVFMP LIF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MSKVVTDVT CPFCGTLCDD LEITVSDDGK EIIDCQNACA IGSEKFLHVR KEGRVTRPRK RQPDGSYKEI SYDEAIEYTA QMLAKAKKTL WYGWASTSCE AMAIGHKVAE KAGTIVDNCA TVCHGSSLLA IQDVGVPSCT LGEVKNRADR IVFWGCNPAH AHPRHMSRYS IFPRGFFTTK GHKGRKIICV DCRYTDTAKC ADEFIQIEQG YDYELLDAFR TVARGQPIPD VVGGVPKEKI ISAVNTLKEG RFGVIFFGMG LTHTLGRNHN IDIAINLTRD LNDFTKFSII AMRGHWNVTG SGQVLSWQYG FPYCVDLTRR THARYNPGET SSVDLLRRKE VDACICIASD IGAHFPIEAT RHMAQIPSVC IDPHINLTTE ISDVHIPVAL VGVEVEGCAY RMDNVPIACR KVVEPPEGML TDEELLEKVY DRLCEIMGDA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430
PF00384: 52-217 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
Sequence: MSKVVTDVT CPFCGTLCDD LEITVSDDGK EIIDCQNACA IGSEKFLHVR KEGRVTRPRK RQPDGSYKEI SYDEAIEYTA QMLAKAKKTL WYGWASTSCE AMAIGHKVAE KAGTIVDNCA TVCHGSSLLA IQDVGVPSCT LGEVKNRADR IVFWGCNPAH AHPRHMSRYS IFPRGFFTTK GHKGRKIICV DCRYTDTAKC ADEFIQIEQG YDYELLDAFR TVARGQPIPD VVGGVPKEKI ISAVNTLKEG RFGVIFFGMG LTHTLGRNHN IDIAINLTRD LNDFTKFSII AMRGHWNVTG SGQVLSWQYG FPYCVDLTRR THARYNPGET SSVDLLRRKE VDACICIASD IGAHFPIEAT RHMAQIPSVC IDPHINLTTE ISDVHIPVAL VGVEVEGCAY RMDNVPIACR KVVEPPEGML TDEELLEKVY DRLCEIMGDA HMM: 111-290 GTIVDNCA TVCHGSSLLA IQDVGVPSCT LGEVKNRADR IVFWGCNPAH AHPRHMSRYS IFPRGFFTTK GHKGRKIICV DCRYTDTAKC ADEFIQIEQG YDYELLDAFR TVARGQPIPD VVGGVPKEKI ISAVNTLKEG RFGVIFFGMG LTHTLGRNHN IDIAINLTRD LNDFTKFSII AM ALI: 34-214 QNACA IGSEKFLHVR KEGRVTRPRK RQPDGSYKEI SYDEAIEYTA QMLAKAKKTL WYGWASTSCE AMAIGHKVAE KAGTIVDNCA TVCHGSSLLA IQDVGVPSCT LGEVKNRADR IVFWGCNPAH AHPRHMSRYS IFPRGFFTTK GHKGRKIICV DCRYTDTAKC ADEFIQIEQG YDYELL ENV: 30-222 IIDCQNACA IGSEKFLHVR KEGRVTRPRK RQPDGSYKEI SYDEAIEYTA QMLAKAKKTL WYGWASTSCE AMAIGHKVAE KAGTIVDNCA TVCHGSSLLA IQDVGVPSCT LGEVKNRADR IVFWGCNPAH AHPRHMSRYS IFPRGFFTTK GHKGRKIICV DCRYTDTAKC ADEFIQIEQG YDYELLDAFR TVAR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430
Sequence: MSKVVTDVT CPFCGTLCDD LEITVSDDGK EIIDCQNACA IGSEKFLHVR KEGRVTRPRK RQPDGSYKEI SYDEAIEYTA QMLAKAKKTL WYGWASTSCE AMAIGHKVAE KAGTIVDNCA TVCHGSSLLA IQDVGVPSCT LGEVKNRADR IVFWGCNPAH AHPRHMSRYS IFPRGFFTTK GHKGRKIICV DCRYTDTAKC ADEFIQIEQG YDYELLDAFR TVARGQPIPD VVGGVPKEKI ISAVNTLKEG RFGVIFFGMG LTHTLGRNHN IDIAINLTRD LNDFTKFSII AMRGHWNVTG SGQVLSWQYG FPYCVDLTRR THARYNPGET SSVDLLRRKE VDACICIASD IGAHFPIEAT RHMAQIPSVC IDPHINLTTE ISDVHIPVAL VGVEVEGCAY RMDNVPIACR KVVEPPEGML TDEELLEKVY DRLCEIMGDA HMM: 126-175 LLA IQDVGVPSCT LGEVKNRADR IVFWGCNPAH AHPRHMSRYS IFPRGFF ALI: 33-83 CQNACA IGSEKFLHVR KEGRVTRPRK RQPDGSYKEI SYDEAIEYTA QMLAK ENV: 29-95 EIIDCQNACA IGSEKFLHVR KEGRVTRPRK RQPDGSYKEI SYDEAIEYTA QMLAKAKKTL WYGWAST Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430
Sequence: MSKVVTDVT CPFCGTLCDD LEITVSDDGK EIIDCQNACA IGSEKFLHVR KEGRVTRPRK RQPDGSYKEI SYDEAIEYTA QMLAKAKKTL WYGWASTSCE AMAIGHKVAE KAGTIVDNCA TVCHGSSLLA IQDVGVPSCT LGEVKNRADR IVFWGCNPAH AHPRHMSRYS IFPRGFFTTK GHKGRKIICV DCRYTDTAKC ADEFIQIEQG YDYELLDAFR TVARGQPIPD VVGGVPKEKI ISAVNTLKEG RFGVIFFGMG LTHTLGRNHN IDIAINLTRD LNDFTKFSII AMRGHWNVTG SGQVLSWQYG FPYCVDLTRR THARYNPGET SSVDLLRRKE VDACICIASD IGAHFPIEAT RHMAQIPSVC IDPHINLTTE ISDVHIPVAL VGVEVEGCAY RMDNVPIACR KVVEPPEGML TDEELLEKVY DRLCEIMGDA HMM: 267-303 HN IDIAINLTRD LNDFTKFSII AMRGHWNVTG SGQVL ALI: 175-211 FTTK GHKGRKIICV DCRYTDTAKC ADEFIQIEQG YDY ENV: 168-217 S IFPRGFFTTK GHKGRKIICV DCRYTDTAKC ADEFIQIEQG YDYELLDAF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430
Sequence: MSKVVTDVT CPFCGTLCDD LEITVSDDGK EIIDCQNACA IGSEKFLHVR KEGRVTRPRK RQPDGSYKEI SYDEAIEYTA QMLAKAKKTL WYGWASTSCE AMAIGHKVAE KAGTIVDNCA TVCHGSSLLA IQDVGVPSCT LGEVKNRADR IVFWGCNPAH AHPRHMSRYS IFPRGFFTTK GHKGRKIICV DCRYTDTAKC ADEFIQIEQG YDYELLDAFR TVARGQPIPD VVGGVPKEKI ISAVNTLKEG RFGVIFFGMG LTHTLGRNHN IDIAINLTRD LNDFTKFSII AMRGHWNVTG SGQVLSWQYG FPYCVDLTRR THARYNPGET SSVDLLRRKE VDACICIASD IGAHFPIEAT RHMAQIPSVC IDPHINLTTE ISDVHIPVAL VGVEVEGCAY RMDNVPIACR KVVEPPEGML TDEELLEKVY DRLCEIMGDA HMM: 266-299 NHN IDIAINLTRD LNDFTKFSII AMRGHWNVTG S ALI: 353-388 FPIEAT RHMAQIPSVC IDPHINLTTE ISDVHIPVAL ENV: 346-397 ASD IGAHFPIEAT RHMAQIPSVC IDPHINLTTE ISDVHIPVAL VGVEVEGCA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430
Sequence: MKPYKCEIC GYIYDPVRGE PKNGIPPGTA FEDLPDTYVC PVCGKANITK REFVPMEAPS GRYRCVACGY LYDPKRGEPK NGIPPGTSFE DLPDTYICPI CGVYAKIGKS EFIATE
10 20 30 40 50 60 70 80 90 100 110
PF00301: 60-103 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
Sequence: MKPYKCEIC GYIYDPVRGE PKNGIPPGTA FEDLPDTYVC PVCGKANITK REFVPMEAPS GRYRCVACGY LYDPKRGEPK NGIPPGTSFE DLPDTYICPI CGVYAKIGKS EFIATE HMM: 424-470 ALI: 2-48 PYKCEIC GYIYDPVRGE PKNGIPPGTA FEDLPDTYVC PVCGKANITK ENV: 1-60 KPYKCEIC GYIYDPVRGE PKNGIPPGTA FEDLPDTYVC PVCGKANITK REFVPMEAPS GR Position: 10 20 30 40 50 60 70 80 90 100 110
Sequence: MKPYKCEIC GYIYDPVRGE PKNGIPPGTA FEDLPDTYVC PVCGKANITK REFVPMEAPS GRYRCVACGY LYDPKRGEPK NGIPPGTSFE DLPDTYICPI CGVYAKIGKS EFIATE HMM: 423-473 ALI: 59-109 GRYRCVACGY LYDPKRGEPK NGIPPGTSFE DLPDTYICPI CGVYAKIGKS E ENV: 48-115 K REFVPMEAPS GRYRCVACGY LYDPKRGEPK NGIPPGTSFE DLPDTYICPI CGVYAKIGKS EFIATE Position: 10 20 30 40 50 60 70 80 90 100 110
Sequence: MASWVCTKC GYLYDDRFGD PEHGVPAGTP FEKIPDSWVC PRCKASKAFF AKRKE
10 20 30 40 50
PF00301: 3-49 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MASWVCTKC GYLYDDRFGD PEHGVPAGTP FEKIPDSWVC PRCKASKAFF AKRKE HMM: 426-469 ALI: 4-47 VCTKC GYLYDDRFGD PEHGVPAGTP FEKIPDSWVC PRCKASKAF ENV: 1-54 ASWVCTKC GYLYDDRFGD PEHGVPAGTP FEKIPDSWVC PRCKASKAFF AKRKE Position: 10 20 30 40 50
Sequence: MQKKGSGHQ LNQKDQSTCD LIFYIIPEEC MNMTKWQCLE CAYVYDPEKG DKTQNIPPGT PFEKLPKTWV CPECKISIQK KGLFVPRE
10 20 30 40 50 60 70 80
PF00301: 33-76 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
Sequence: MQKKGSGHQ LNQKDQSTCD LIFYIIPEEC MNMTKWQCLE CAYVYDPEKG DKTQNIPPGT PFEKLPKTWV CPECKISIQK KGLFVPRE HMM: 417-468 ALI: 26-77 EEC MNMTKWQCLE CAYVYDPEKG DKTQNIPPGT PFEKLPKTWV CPECKISIQ ENV: 2-86 KKGSGHQ LNQKDQSTCD LIFYIIPEEC MNMTKWQCLE CAYVYDPEKG DKTQNIPPGT PFEKLPKTWV CPECKISIQK KGLFVPRE Position: 10 20 30 40 50 60 70 80
Sequence: MFIPVPCDL FNKIGLEGMM QMDSYECTVC GYVYDPAKGD EKNQIPPGTA FEDLPDDWLC PLCLEGKEVF EKVS
10 20 30 40 50 60 70
PF00301: 23-69 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MFIPVPCDL FNKIGLEGMM QMDSYECTVC GYVYDPAKGD EKNQIPPGTA FEDLPDDWLC PLCLEGKEVF EKVS HMM: 421-465 ALI: 19-63 QMDSYECTVC GYVYDPAKGD EKNQIPPGTA FEDLPDDWLC PLCLE ENV: 8-73 L FNKIGLEGMM QMDSYECTVC GYVYDPAKGD EKNQIPPGTA FEDLPDDWLC PLCLEGKEVF EKVS Position: 10 20 30 40 50 60 70
Sequence: MNEIKKPVS SEAVWLYNEI TAHKFLIILA LIFAVIISFL IDVLSGPAWL TVPEIITALI SPEKDTNYFI VWVIRLPMAI MAVFVGAALG VAGAQMQTIL DNPLASPYTL GVSAAAGFGA ALAIVLGVGV LPLGIEFLVP INAFFFSMVC CVSIYLIAWR KKGTTETLVL AGIALLFLFN ALTTMLEYVS SQEDLQAVVF WLFGSMAKAT WSKAAIVGIV ILIVLPFFLK DAWKLTAIRL GDTKAKSLGI HVEKLRIKTL ILVSFLTSIA VCFVGIIGFI GLVAPHISRM LVGEDQRYYL PASLLSGALL LSASSIVSKL VIPGAIFPIG IATSCIGVPF FLYLILRRRS EFW
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF01032: 33-346 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
Sequence: MNEIKKPVS SEAVWLYNEI TAHKFLIILA LIFAVIISFL IDVLSGPAWL TVPEIITALI SPEKDTNYFI VWVIRLPMAI MAVFVGAALG VAGAQMQTIL DNPLASPYTL GVSAAAGFGA ALAIVLGVGV LPLGIEFLVP INAFFFSMVC CVSIYLIAWR KKGTTETLVL AGIALLFLFN ALTTMLEYVS SQEDLQAVVF WLFGSMAKAT WSKAAIVGIV ILIVLPFFLK DAWKLTAIRL GDTKAKSLGI HVEKLRIKTL ILVSFLTSIA VCFVGIIGFI GLVAPHISRM LVGEDQRYYL PASLLSGALL LSASSIVSKL VIPGAIFPIG IATSCIGVPF FLYLILRRRS EFW HMM: 35-135 ISFL IDVLSGPAWL TVPEIITALI SPEKDTNYFI VWVIRLPMAI MAVFVGAALG VAGAQMQTIL DNPLASPYTL GVSAAAGFGA ALAIVLGVGV LPLGIEF ALI: 13-128 WLYNEI TAHKFLIILA LIFAVIISFL IDVLSGPAWL TVPEIITALI SPEKDTNYFI VWVIRLPMAI MAVFVGAALG VAGAQMQTIL DNPLASPYTL GVSAAAGFGA ALAIVLGVGV ENV: 4-130 KKPVS SEAVWLYNEI TAHKFLIILA LIFAVIISFL IDVLSGPAWL TVPEIITALI SPEKDTNYFI VWVIRLPMAI MAVFVGAALG VAGAQMQTIL DNPLASPYTL GVSAAAGFGA ALAIVLGVGV LP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MNEIKKPVS SEAVWLYNEI TAHKFLIILA LIFAVIISFL IDVLSGPAWL TVPEIITALI SPEKDTNYFI VWVIRLPMAI MAVFVGAALG VAGAQMQTIL DNPLASPYTL GVSAAAGFGA ALAIVLGVGV LPLGIEFLVP INAFFFSMVC CVSIYLIAWR KKGTTETLVL AGIALLFLFN ALTTMLEYVS SQEDLQAVVF WLFGSMAKAT WSKAAIVGIV ILIVLPFFLK DAWKLTAIRL GDTKAKSLGI HVEKLRIKTL ILVSFLTSIA VCFVGIIGFI GLVAPHISRM LVGEDQRYYL PASLLSGALL LSASSIVSKL VIPGAIFPIG IATSCIGVPF FLYLILRRRS EFW HMM: 205-256 AKAT WSKAAIVGIV ILIVLPFFLK DAWKLTAIRL GDTKAKSLGI HVEKLRIK ALI: 228-279 K DAWKLTAIRL GDTKAKSLGI HVEKLRIKTL ILVSFLTSIA VCFVGIIGFI G ENV: 222-286 VLPFFLK DAWKLTAIRL GDTKAKSLGI HVEKLRIKTL ILVSFLTSIA VCFVGIIGFI GLVAPHIS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MSKWYCPRC GFMYNEAVGD ENLKIPPKTL FSSFDSSWVC PRCQTPKELF VEVMA
10 20 30 40 50
PF00301: 2-49 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MSKWYCPRC GFMYNEAVGD ENLKIPPKTL FSSFDSSWVC PRCQTPKELF VEVMA HMM: 425-469 ALI: 3-47 WYCPRC GFMYNEAVGD ENLKIPPKTL FSSFDSSWVC PRCQTPKEL ENV: 1-54 SKWYCPRC GFMYNEAVGD ENLKIPPKTL FSSFDSSWVC PRCQTPKELF VEVMA Position: 10 20 30 40 50
Sequence: MDLTVTAVL MFIIALIVSA VIIYIITKIF GETEDIKTAF IAAIVGTVIY TLIYYLIGQG LIAAFIAGIV WLIALQKLYT IGWVKSLIIA VVIWIVTSIV GWFLPHLTGP L
10 20 30 40 50 60 70 80 90 100 110
Sequence: MDLTVTAVL MFIIALIVSA VIIYIITKIF GETEDIKTAF IAAIVGTVIY TLIYYLIGQG LIAAFIAGIV WLIALQKLYT IGWVKSLIIA VVIWIVTSIV GWFLPHLTGP L HMM: 47-134 IY TLIYYLIGQG LIAAFIAGIV WLIALQKLYT IGWVKSLIIA VVIWIVTSIV GWFLPHLTGP L ALI: 8-98 L MFIIALIVSA VIIYIITKIF GETEDIKTAF IAAIVGTVIY TLIYYLIGQG LIAAFIAGIV WLIALQKLYT IGWVKSLIIA VVIWIVTSIV ENV: 1-105 DLTVTAVL MFIIALIVSA VIIYIITKIF GETEDIKTAF IAAIVGTVIY TLIYYLIGQG LIAAFIAGIV WLIALQKLYT IGWVKSLIIA VVIWIVTSIV GWFLPHL Position: 10 20 30 40 50 60 70 80 90 100 110
Sequence: MGDRSVADR LKDFGEVDNG LSPEEAIEEA SRCLQCKKPA CVDGCPVNID IPAFVAFIAK GEFLKAAESI RQQNLLPAIC GRVCPQETQC EALCILGKKD TPIRIGQLER FAADQERAKG LTVPARKTAT GKRVAVIGSG PAGIVAAGEL AKDGHDVILY ESLHAPGGVL TYGIPSFRLP KDVVKAEIDL ILAMGVDLRL NHLVGRTVSH QELEGYDAIL LGTGAGLPYF MGIPGENLSG VYSANEFLTR INLMHAERFP EFDTPVARMS RVVVVGGGNV AMDAARTARR MGAKVTLVYR RREEDLPARA AEVHHAQEEG IEFITCANPV RILGDQAVTG IECIRMHMCN LDESGRPVPE PIDNDTFTLD CDVVIQAIGQ GPNPVLVSQI PDLDKGKAGN VVTGEDGRTS HPKIFAAGDV TTGAATVIMA MGGAKQAARS ISEMLGSR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
PF14691: 9-119 ♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
PF07992: 130-431 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
Sequence: MGDRSVADR LKDFGEVDNG LSPEEAIEEA SRCLQCKKPA CVDGCPVNID IPAFVAFIAK GEFLKAAESI RQQNLLPAIC GRVCPQETQC EALCILGKKD TPIRIGQLER FAADQERAKG LTVPARKTAT GKRVAVIGSG PAGIVAAGEL AKDGHDVILY ESLHAPGGVL TYGIPSFRLP KDVVKAEIDL ILAMGVDLRL NHLVGRTVSH QELEGYDAIL LGTGAGLPYF MGIPGENLSG VYSANEFLTR INLMHAERFP EFDTPVARMS RVVVVGGGNV AMDAARTARR MGAKVTLVYR RREEDLPARA AEVHHAQEEG IEFITCANPV RILGDQAVTG IECIRMHMCN LDESGRPVPE PIDNDTFTLD CDVVIQAIGQ GPNPVLVSQI PDLDKGKAGN VVTGEDGRTS HPKIFAAGDV TTGAATVIMA MGGAKQAARS ISEMLGSR HMM: 171-206 GIPSFRLP KDVVKAEIDL ILAMGVDLRL NHLVGRTV ALI: 123-158 ARKTAT GKRVAVIGSG PAGIVAAGEL AKDGHDVILY ENV: 105-170 QLER FAADQERAKG LTVPARKTAT GKRVAVIGSG PAGIVAAGEL AKDGHDVILY ESLHAPGGVL TY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
Sequence: MGDRSVADR LKDFGEVDNG LSPEEAIEEA SRCLQCKKPA CVDGCPVNID IPAFVAFIAK GEFLKAAESI RQQNLLPAIC GRVCPQETQC EALCILGKKD TPIRIGQLER FAADQERAKG LTVPARKTAT GKRVAVIGSG PAGIVAAGEL AKDGHDVILY ESLHAPGGVL TYGIPSFRLP KDVVKAEIDL ILAMGVDLRL NHLVGRTVSH QELEGYDAIL LGTGAGLPYF MGIPGENLSG VYSANEFLTR INLMHAERFP EFDTPVARMS RVVVVGGGNV AMDAARTARR MGAKVTLVYR RREEDLPARA AEVHHAQEEG IEFITCANPV RILGDQAVTG IECIRMHMCN LDESGRPVPE PIDNDTFTLD CDVVIQAIGQ GPNPVLVSQI PDLDKGKAGN VVTGEDGRTS HPKIFAAGDV TTGAATVIMA MGGAKQAARS ISEMLGSR HMM: 163-209 APGGVL TYGIPSFRLP KDVVKAEIDL ILAMGVDLRL NHLVGRTVSH Q ALI: 251-299 LMHAERFP EFDTPVARMS RVVVVGGGNV AMDAARTARR MGAKVTLVYR R ENV: 239-310 VYSANEFLTR INLMHAERFP EFDTPVARMS RVVVVGGGNV AMDAARTARR MGAKVTLVYR RREEDLPARA AE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
Sequence: MPKVIENVG CPYCGCSCDD VRVTVSDDGK DILEVENVCA IGTEIFKHGC SKDRIKLPRL RQPDGSMKEI SYDEAIEWTA RHLIKAKKPL MYGFGSTNCE GQAAAARVME ISGGMLDNCA TICHGPSFLA IFDNGYPTCT LGEVKNRADV IVYWGSNPAH AHPRHMSRYS IFPRGFFTGK GQKKRTVIVI DPRFTDTANV ADYHLQVKQG HDYELFNAFR MVVNGHGDDL PDEVAGIKKE TILEVAEIMK NARFGTTFFG MGLTHSDGRN HNIDIAISLT RDLNKVSKWT IMAMRGHYNI AGPGVVWSWT FGFPYCLDLT KQNHAHMNPG ETSSVDMAMR DEVDMFINIG TDAGAHFPYP AVKQLKKHPW VTIDPSINMA SEISDLHIPV CICGVDVGGI VYRMDNVPIQ FRKVIEPPEG VMDDETLLNK IADRMEELIA KGEA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
PF00384: 52-278 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MPKVIENVG CPYCGCSCDD VRVTVSDDGK DILEVENVCA IGTEIFKHGC SKDRIKLPRL RQPDGSMKEI SYDEAIEWTA RHLIKAKKPL MYGFGSTNCE GQAAAARVME ISGGMLDNCA TICHGPSFLA IFDNGYPTCT LGEVKNRADV IVYWGSNPAH AHPRHMSRYS IFPRGFFTGK GQKKRTVIVI DPRFTDTANV ADYHLQVKQG HDYELFNAFR MVVNGHGDDL PDEVAGIKKE TILEVAEIMK NARFGTTFFG MGLTHSDGRN HNIDIAISLT RDLNKVSKWT IMAMRGHYNI AGPGVVWSWT FGFPYCLDLT KQNHAHMNPG ETSSVDMAMR DEVDMFINIG TDAGAHFPYP AVKQLKKHPW VTIDPSINMA SEISDLHIPV CICGVDVGGI VYRMDNVPIQ FRKVIEPPEG VMDDETLLNK IADRMEELIA KGEA HMM: 269-308 HNIDIAISLT RDLNKVSKWT IMAMRGHYNI AGPGVVWSWT ALI: 177-216 GK GQKKRTVIVI DPRFTDTANV ADYHLQVKQG HDYELFNA ENV: 36-227 VCA IGTEIFKHGC SKDRIKLPRL RQPDGSMKEI SYDEAIEWTA RHLIKAKKPL MYGFGSTNCE GQAAAARVME ISGGMLDNCA TICHGPSFLA IFDNGYPTCT LGEVKNRADV IVYWGSNPAH AHPRHMSRYS IFPRGFFTGK GQKKRTVIVI DPRFTDTANV ADYHLQVKQG HDYELFNAFR MVVNGHGDD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
Sequence: MPKVIENVG CPYCGCSCDD VRVTVSDDGK DILEVENVCA IGTEIFKHGC SKDRIKLPRL RQPDGSMKEI SYDEAIEWTA RHLIKAKKPL MYGFGSTNCE GQAAAARVME ISGGMLDNCA TICHGPSFLA IFDNGYPTCT LGEVKNRADV IVYWGSNPAH AHPRHMSRYS IFPRGFFTGK GQKKRTVIVI DPRFTDTANV ADYHLQVKQG HDYELFNAFR MVVNGHGDDL PDEVAGIKKE TILEVAEIMK NARFGTTFFG MGLTHSDGRN HNIDIAISLT RDLNKVSKWT IMAMRGHYNI AGPGVVWSWT FGFPYCLDLT KQNHAHMNPG ETSSVDMAMR DEVDMFINIG TDAGAHFPYP AVKQLKKHPW VTIDPSINMA SEISDLHIPV CICGVDVGGI VYRMDNVPIQ FRKVIEPPEG VMDDETLLNK IADRMEELIA KGEA HMM: 279-300 RDLNKVSKWT IMAMRGHYNI AG ALI: 370-391 TIDPSINMA SEISDLHIPV CIC ENV: 360-397 VKQLKKHPW VTIDPSINMA SEISDLHIPV CICGVDVGG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
Sequence: MPESPIAQS NSLVKLAFSI YSSPGAYALL LGSGVSRSAE ILTGWEVMLD LIQRVGKING EKKLDNPVQW YQEKFGKEPS YDTLLDELTS SQAGRRDLLA NYFEPREADI DEGRKIPQAA HRAIASLVKT GYIKIIITTN FDRLIETAVY DIGFHPYVIF HESGIRSCPP PAHIQHSCII FKIHGDYLDT QLRNTPEELA RYPDLINQYL DRIFDEFGLI TCGWSGEYDC AIIERLKARR SDSPYPIYVS SRGKKKPAIQ ELLKIPNTIP VEISDADDFF EKLSENVTFL MEHNKEPLTD ELLVIRVRKY LSDTKNQIKL WELLNTEVKS VQEKNNNEIL RAISKTSFTV KDLMAHFETN IKNLEIICMN VAFFGDQSYS PFFRSIIEQL MTVQEKGWYN KLVSLQYYPA LLIAYISGII LLKDDKFSQL SELLLNPICY DYNERKPSIS IINTRTVFRD SAEKQIDYPN AENLYAPVSE YLYHRLKDPL STFFSNENHY SETFDLFEYL LSLIYIDQIY PDLSKGRIWS PIGRYNWKRE SYYNEKTPFF EQKVEQWLHQ GENLSLFKEG FFQASPERLN QCHQGLLLLL KSSKEQWIRI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590
Sequence: MPESPIAQS NSLVKLAFSI YSSPGAYALL LGSGVSRSAE ILTGWEVMLD LIQRVGKING EKKLDNPVQW YQEKFGKEPS YDTLLDELTS SQAGRRDLLA NYFEPREADI DEGRKIPQAA HRAIASLVKT GYIKIIITTN FDRLIETAVY DIGFHPYVIF HESGIRSCPP PAHIQHSCII FKIHGDYLDT QLRNTPEELA RYPDLINQYL DRIFDEFGLI TCGWSGEYDC AIIERLKARR SDSPYPIYVS SRGKKKPAIQ ELLKIPNTIP VEISDADDFF EKLSENVTFL MEHNKEPLTD ELLVIRVRKY LSDTKNQIKL WELLNTEVKS VQEKNNNEIL RAISKTSFTV KDLMAHFETN IKNLEIICMN VAFFGDQSYS PFFRSIIEQL MTVQEKGWYN KLVSLQYYPA LLIAYISGII LLKDDKFSQL SELLLNPICY DYNERKPSIS IINTRTVFRD SAEKQIDYPN AENLYAPVSE YLYHRLKDPL STFFSNENHY SETFDLFEYL LSLIYIDQIY PDLSKGRIWS PIGRYNWKRE SYYNEKTPFF EQKVEQWLHQ GENLSLFKEG FFQASPERLN QCHQGLLLLL KSSKEQWIRI HMM: 671-729 ALI: 26-88 ALL LGSGVSRSAE ILTGWEVMLD LIQRVGKING EKKLDNPVQW YQEKFGKEPS YDTLLDELTS ENV: 13-95 KLAFSI YSSPGAYALL LGSGVSRSAE ILTGWEVMLD LIQRVGKING EKKLDNPVQW YQEKFGKEPS YDTLLDELTS SQAGRRD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590
Sequence: METKVGYFA SIEQYKPMDA LEQSVRAEKV GFDSIWVDDH FHPWYHSDAQ SGQAWAWMGA TLQATKKVFV STCITCPILR YNPGVVAQTF ATLRQMYPKR VGVAVGAGEA LNEVPVTGQW PSVPERQEMT IEAIEVMRKL WESKTPVTFK GKYYTLEKAF MYTKPEDEVP LYFSGMGPKG AKLAGIHGDH LMTVSADTET LKNVTIPKFE EGAKEAGKDP KKMEKAMLIW YSVDPDFEKA VEGNRFWAGC LVPAMFKYRV SDPPEVELHA NAVGSEMIKK NFLCATDAEG LIHEIERFKN AGITHFCLGN SSPNVNYGID IFKDVIPAVK D
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330
PF00296: 3-304 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌
Sequence: METKVGYFA SIEQYKPMDA LEQSVRAEKV GFDSIWVDDH FHPWYHSDAQ SGQAWAWMGA TLQATKKVFV STCITCPILR YNPGVVAQTF ATLRQMYPKR VGVAVGAGEA LNEVPVTGQW PSVPERQEMT IEAIEVMRKL WESKTPVTFK GKYYTLEKAF MYTKPEDEVP LYFSGMGPKG AKLAGIHGDH LMTVSADTET LKNVTIPKFE EGAKEAGKDP KKMEKAMLIW YSVDPDFEKA VEGNRFWAGC LVPAMFKYRV SDPPEVELHA NAVGSEMIKK NFLCATDAEG LIHEIERFKN AGITHFCLGN SSPNVNYGID IFKDVIPAVK D HMM: 157-175 AF MYTKPEDEVP LYFSGMG ALI: 124-142 RQEMT IEAIEVMRKL WESK ENV: 64-144 KKVFV STCITCPILR YNPGVVAQTF ATLRQMYPKR VGVAVGAGEA LNEVPVTGQW PSVPERQEMT IEAIEVMRKL WESKTP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330
Sequence: METKVGYFA SIEQYKPMDA LEQSVRAEKV GFDSIWVDDH FHPWYHSDAQ SGQAWAWMGA TLQATKKVFV STCITCPILR YNPGVVAQTF ATLRQMYPKR VGVAVGAGEA LNEVPVTGQW PSVPERQEMT IEAIEVMRKL WESKTPVTFK GKYYTLEKAF MYTKPEDEVP LYFSGMGPKG AKLAGIHGDH LMTVSADTET LKNVTIPKFE EGAKEAGKDP KKMEKAMLIW YSVDPDFEKA VEGNRFWAGC LVPAMFKYRV SDPPEVELHA NAVGSEMIKK NFLCATDAEG LIHEIERFKN AGITHFCLGN SSPNVNYGID IFKDVIPAVK D HMM: 200-280 KNVTIPKFE EGAKEAGKDP KKMEKAMLIW YSVDPDFEKA VEGNRFWAGC LVPAMFKYRV SDPPEVELHA NAVGSEMIKK NF ALI: 146-226 TFK GKYYTLEKAF MYTKPEDEVP LYFSGMGPKG AKLAGIHGDH LMTVSADTET LKNVTIPKFE EGAKEAGKDP KKMEKAML ENV: 141-244 SKTPVTFK GKYYTLEKAF MYTKPEDEVP LYFSGMGPKG AKLAGIHGDH LMTVSADTET LKNVTIPKFE EGAKEAGKDP KKMEKAMLIW YSVDPDFEKA VEGNRF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330
Sequence: METKVGYFA SIEQYKPMDA LEQSVRAEKV GFDSIWVDDH FHPWYHSDAQ SGQAWAWMGA TLQATKKVFV STCITCPILR YNPGVVAQTF ATLRQMYPKR VGVAVGAGEA LNEVPVTGQW PSVPERQEMT IEAIEVMRKL WESKTPVTFK GKYYTLEKAF MYTKPEDEVP LYFSGMGPKG AKLAGIHGDH LMTVSADTET LKNVTIPKFE EGAKEAGKDP KKMEKAMLIW YSVDPDFEKA VEGNRFWAGC LVPAMFKYRV SDPPEVELHA NAVGSEMIKK NFLCATDAEG LIHEIERFKN AGITHFCLGN SSPNVNYGID IFKDVIPAVK D HMM: 97-217 KR VGVAVGAGEA LNEVPVTGQW PSVPERQEMT IEAIEVMRKL WESKTPVTFK GKYYTLEKAF MYTKPEDEVP LYFSGMGPKG AKLAGIHGDH LMTVSADTET LKNVTIPKFE EGAKEAGKD ALI: 81-202 PGVVAQTF ATLRQMYPKR VGVAVGAGEA LNEVPVTGQW PSVPERQEMT IEAIEVMRKL WESKTPVTFK GKYYTLEKAF MYTKPEDEVP LYFSGMGPKG AKLAGIHGDH LMTVSADTET LKNV ENV: 58-226 A TLQATKKVFV STCITCPILR YNPGVVAQTF ATLRQMYPKR VGVAVGAGEA LNEVPVTGQW PSVPERQEMT IEAIEVMRKL WESKTPVTFK GKYYTLEKAF MYTKPEDEVP LYFSGMGPKG AKLAGIHGDH LMTVSADTET LKNVTIPKFE EGAKEAGKDP KKMEKAML Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330
Sequence: MHHIDISIE KDIFSTNKKL ADANAAHLHA HGVRAFDLLG GIGSGKTALI EKVVPKLKDR GMHAAAIAGD VYGDDDFQRI IALGIPAENV NTGKECHLDA HMIEHALDHL PLDGVNILFI ENVGNMVCPT DFELGAEKRI VVVSSTEGDD VVNKHPMMFR GCSIGVLNKI DLADAVGADL NRMEQDMRRY NPSMKIFRTN MKTGEGIDPL IDEILS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210
PF02492: 36-196 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
Sequence: MHHIDISIE KDIFSTNKKL ADANAAHLHA HGVRAFDLLG GIGSGKTALI EKVVPKLKDR GMHAAAIAGD VYGDDDFQRI IALGIPAENV NTGKECHLDA HMIEHALDHL PLDGVNILFI ENVGNMVCPT DFELGAEKRI VVVSSTEGDD VVNKHPMMFR GCSIGVLNKI DLADAVGADL NRMEQDMRRY NPSMKIFRTN MKTGEGIDPL IDEILS HMM: 372-428 ALI: 10-65 DIFSTNKKL ADANAAHLHA HGVRAFDLLG GIGSGKTALI EKVVPKLKDR GMHAAAI ENV: 2-91 HIDISIE KDIFSTNKKL ADANAAHLHA HGVRAFDLLG GIGSGKTALI EKVVPKLKDR GMHAAAIAGD VYGDDDFQRI IALGIPAENV NTG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210
Sequence: MNHLFPFTE ITGQEHAKKA LLCALVCDDI RSILILGNPG TAKSALVRSV ETLTDRKKVI TIPQNVTYDR LLGTIDLEKV ITSGNMHVHP GILQEGNNQI LYADDINLMD EGVIQSILST SETGQYLLER EGLSRMISTR FTFLASMDPA EGELSSGQMD RFDLCIRTDQ ITETGMRAEI IRKALSFEHS PDAFVLGCEK ETDDLKKNIQ AAKERFLYVS IPDGHADLIS SLCIELAVQG YRGDIAVART AKALAALDRR DEVIFDDIKL AALFALEHRR GDRQDRPPHP PHSEKEERPE QDSDKNRSEK QNQPDTRSDD QIGEQDKKNQ EKNQIPTPPP DRYFDIGSPF EVIRYLDENT WQVTQKQKSG RRSRVISSDS SGHYRSFRYP GRCRNDIAVD ATIRAAAPYQ RIRNRNGLAI SVKKTDIREK VREKKIAHTI LFLVDASGSM GVQKRMVAVK GAILSLLNDA YQKRDRVGLM IFRGDSADLL LPPTRSPELA AKLLKAIPTG GKTPLLKGLT EGYLLLTRGK YAAPGENKSI VLLTDGRGNM PLTNKAPGEE LALIARKITG TGVRFVVVDT ESGFPRLDRA RILARDLNGS YFRLEDLSIH GLAGCVNELM YSER
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620
PF00493: 7-153 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF17863: 226-298 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF13519: 438-545 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
Sequence: MNHLFPFTE ITGQEHAKKA LLCALVCDDI RSILILGNPG TAKSALVRSV ETLTDRKKVI TIPQNVTYDR LLGTIDLEKV ITSGNMHVHP GILQEGNNQI LYADDINLMD EGVIQSILST SETGQYLLER EGLSRMISTR FTFLASMDPA EGELSSGQMD RFDLCIRTDQ ITETGMRAEI IRKALSFEHS PDAFVLGCEK ETDDLKKNIQ AAKERFLYVS IPDGHADLIS SLCIELAVQG YRGDIAVART AKALAALDRR DEVIFDDIKL AALFALEHRR GDRQDRPPHP PHSEKEERPE QDSDKNRSEK QNQPDTRSDD QIGEQDKKNQ EKNQIPTPPP DRYFDIGSPF EVIRYLDENT WQVTQKQKSG RRSRVISSDS SGHYRSFRYP GRCRNDIAVD ATIRAAAPYQ RIRNRNGLAI SVKKTDIREK VREKKIAHTI LFLVDASGSM GVQKRMVAVK GAILSLLNDA YQKRDRVGLM IFRGDSADLL LPPTRSPELA AKLLKAIPTG GKTPLLKGLT EGYLLLTRGK YAAPGENKSI VLLTDGRGNM PLTNKAPGEE LALIARKITG TGVRFVVVDT ESGFPRLDRA RILARDLNGS YFRLEDLSIH GLAGCVNELM YSER HMM: 138-199 R FTFLASMDPA EGELSSGQMD RFDLCIRTDQ ITETGMRAEI IRKALSFEHS PDAFVLGCEK E ALI: 78-138 V ITSGNMHVHP GILQEGNNQI LYADDINLMD EGVIQSILST SETGQYLLER EGLSRMISTR ENV: 55-146 KKVI TIPQNVTYDR LLGTIDLEKV ITSGNMHVHP GILQEGNNQI LYADDINLMD EGVIQSILST SETGQYLLER EGLSRMISTR FTFLASMD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620
Sequence: MEEEKKKEV DLQISGMHCA TCAISVEKGL AATPGVMESK VNLATGKARI SYDPSQVSLH DLTHAVEKSG FSVSHEKIIV KVGGMTCASC VQTVTHALLT LEGIISADVN LNTERAYVTY NPSLVGIGDI RNVIISAGYQ FLGTDRDKED ESDKIREREL SSQLRKIILG FALSLLMMGM MYIPSHDMHL ISYLQFIITT PVLIWLGSPI FRAAFTSLRN KTLNMDVMYA MGIGVAYGAS VLGTFSIILD MSTLFYETAL MLTAFLMLGR YLEARAKGRT SSAIKSLIGL QAESASVIRD GEEREIPVQD VLPGDIIQMR TGARIPVDGV IFSGSSYVDE SMVTGEPLAV FRESGHEVIG GTLVTTGAFQ YKATRVGSDT MLARIIRLVE EAQGSRPPVQ RLADYVVAWF IPAVLLIAVL AFSYWYGIRG MDLRFSLQTM IAVLVVACPC ALGLATPTAV TVGIGRGAEF GILIRNGSVL EIANKITLAL FDKTGTITQG KPVVTDVDSF TGNPGLLISM AASLEHLSDH PISSAILSKS KEEGIIPAEV QDFQTVSGSG LSGIIAGGIV RLGVRDYILS SGLSLTPPQD AIHTQREREG KTTVLVSRDS SILGLISIAD QVKPEAGSCV RILNEMGIRS GMVTGDNKVT ADAVASMVGI HEVFARVLPE GKEQEVSRVQ KSGDVVAFIG DGINDAPALA RADTGIAIGS GTDIAIESAD IVLVRDSLIH IPAAIQLARK VMGRIRLNLF WAFAYNIILI PLAAGILYPV ILFKPEYGAL AMAFSSVTVI SLSLLLKRYI PPALSYIERE NHSKKELEKD PICGMMVDPK TAQYWSDFNE KRYYFCNKGC KETFDSNPEK YK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860
PF00403: 78-139 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
PF00122: 288-467 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00702: 484-702 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF04945: 817-861 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
Sequence: MEEEKKKEV DLQISGMHCA TCAISVEKGL AATPGVMESK VNLATGKARI SYDPSQVSLH DLTHAVEKSG FSVSHEKIIV KVGGMTCASC VQTVTHALLT LEGIISADVN LNTERAYVTY NPSLVGIGDI RNVIISAGYQ FLGTDRDKED ESDKIREREL SSQLRKIILG FALSLLMMGM MYIPSHDMHL ISYLQFIITT PVLIWLGSPI FRAAFTSLRN KTLNMDVMYA MGIGVAYGAS VLGTFSIILD MSTLFYETAL MLTAFLMLGR YLEARAKGRT SSAIKSLIGL QAESASVIRD GEEREIPVQD VLPGDIIQMR TGARIPVDGV IFSGSSYVDE SMVTGEPLAV FRESGHEVIG GTLVTTGAFQ YKATRVGSDT MLARIIRLVE EAQGSRPPVQ RLADYVVAWF IPAVLLIAVL AFSYWYGIRG MDLRFSLQTM IAVLVVACPC ALGLATPTAV TVGIGRGAEF GILIRNGSVL EIANKITLAL FDKTGTITQG KPVVTDVDSF TGNPGLLISM AASLEHLSDH PISSAILSKS KEEGIIPAEV QDFQTVSGSG LSGIIAGGIV RLGVRDYILS SGLSLTPPQD AIHTQREREG KTTVLVSRDS SILGLISIAD QVKPEAGSCV RILNEMGIRS GMVTGDNKVT ADAVASMVGI HEVFARVLPE GKEQEVSRVQ KSGDVVAFIG DGINDAPALA RADTGIAIGS GTDIAIESAD IVLVRDSLIH IPAAIQLARK VMGRIRLNLF WAFAYNIILI PLAAGILYPV ILFKPEYGAL AMAFSSVTVI SLSLLLKRYI PPALSYIERE NHSKKELEKD PICGMMVDPK TAQYWSDFNE KRYYFCNKGC KETFDSNPEK YK HMM: 414-445 LIAVL AFSYWYGIRG MDLRFSLQTM IAVLVVA ALI: 830-861 AQYWSDFNE KRYYFCNKGC KETFDSNPEK YK ENV: 815-861 LEKD PICGMMVDPK TAQYWSDFNE KRYYFCNKGC KETFDSNPEK YK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860
Sequence: MEEEKKKEV DLQISGMHCA TCAISVEKGL AATPGVMESK VNLATGKARI SYDPSQVSLH DLTHAVEKSG FSVSHEKIIV KVGGMTCASC VQTVTHALLT LEGIISADVN LNTERAYVTY NPSLVGIGDI RNVIISAGYQ FLGTDRDKED ESDKIREREL SSQLRKIILG FALSLLMMGM MYIPSHDMHL ISYLQFIITT PVLIWLGSPI FRAAFTSLRN KTLNMDVMYA MGIGVAYGAS VLGTFSIILD MSTLFYETAL MLTAFLMLGR YLEARAKGRT SSAIKSLIGL QAESASVIRD GEEREIPVQD VLPGDIIQMR TGARIPVDGV IFSGSSYVDE SMVTGEPLAV FRESGHEVIG GTLVTTGAFQ YKATRVGSDT MLARIIRLVE EAQGSRPPVQ RLADYVVAWF IPAVLLIAVL AFSYWYGIRG MDLRFSLQTM IAVLVVACPC ALGLATPTAV TVGIGRGAEF GILIRNGSVL EIANKITLAL FDKTGTITQG KPVVTDVDSF TGNPGLLISM AASLEHLSDH PISSAILSKS KEEGIIPAEV QDFQTVSGSG LSGIIAGGIV RLGVRDYILS SGLSLTPPQD AIHTQREREG KTTVLVSRDS SILGLISIAD QVKPEAGSCV RILNEMGIRS GMVTGDNKVT ADAVASMVGI HEVFARVLPE GKEQEVSRVQ KSGDVVAFIG DGINDAPALA RADTGIAIGS GTDIAIESAD IVLVRDSLIH IPAAIQLARK VMGRIRLNLF WAFAYNIILI PLAAGILYPV ILFKPEYGAL AMAFSSVTVI SLSLLLKRYI PPALSYIERE NHSKKELEKD PICGMMVDPK TAQYWSDFNE KRYYFCNKGC KETFDSNPEK YK HMM: 422-449 YWYGIRG MDLRFSLQTM IAVLVVACPC A ALI: 833-860 WSDFNE KRYYFCNKGC KETFDSNPEK YK ENV: 824-861 MVDPK TAQYWSDFNE KRYYFCNKGC KETFDSNPEK YK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF04879: 0-55 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00384: 57-483 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF01568: 570-677 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 103-312 NEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGN ALI: 35-238 PVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC ENV: 5-242 TTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 387-469 PG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG E ALI: 242-328 DELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN ENV: 239-340 NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 609-687 AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK ALI: 412-488 HALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA ENV: 407-516 LT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYER Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 837-918 ALI: 567-650 EY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HY ENV: 556-656 PFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAAN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 101-310 VSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LT ALI: 36-239 VNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC N ENV: 5-249 TTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV M Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 395-466 IMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNP ALI: 254-325 SLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRG ENV: 241-365 FDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 611-679 KLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK I ALI: 417-483 LD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAK ENV: 393-491 LYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 815-900 ALI: 564-648 PDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF ENV: 556-660 PFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 127-328 RL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN ALI: 43-238 PKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC ENV: 7-241 CP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 402-482 ISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAA ALI: 242-324 DELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALR ENV: 239-334 NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 567-703 EY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK ALI: 350-489 DEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA Q ENV: 332-495 ACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MKYVQTTCP YCGTGCSFNL VVDKGIVTGV APYQRSPVNE GKLCPKGTYA HEFINNPDRL KKPLIKKDGK FVEASWDEAL KLVAEKFKSY KPDECACLAS ARVSNEDNYA MMKFARGVLK TKHIDHCARL CHASTVAGLA NIFGSGAMTN SIGDIAESKC VFIIGSNTFE CHPLIGRRVM QAKAKGAKVI YADPRYTPTG KQADLYLQFR SGTDVALLNG MMQEIIRNGW ENKEFIQNRC NGFDELKKEV MKDDYSLENV SKITGVPADK IKTAAEWFAK SGASAILYSM GITQHTTGVD NVKSCGNLQM LTGNLGRPGT GVNALRGQNN VQGACDMGCL PVVYTAYQKV IDEAAQKKFA DGWKFPDGIA KGENGYEVTT LMNVLTEKPG EIKCLYIMGE NPMISDPDLT HVEHALKTLD FLVVQDIFLN ETAEFADVVL PAACYAEKDG TQTSTERRVQ MWRKAQNPPG EAKGDWEIIA SIAAKMGYGA QFPWKTSEDV FNEMASLTPS YAGMTYERLN RPEALHWPCP TTDHPGTPIL HTEKFGMPDG KGLMTGIPFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL TINALDPIAK IPESKACAVK IEKIAEAK HMM: 840-921 ALI: 567-649 EY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF H ENV: 556-658 PFK WPQEVPDSEY PFVLTTGRSI WQWHTGTMTR RSASLEREEP TGWVEINTED AKKLGIADKE KVKAKTRRGE ITIPARVTPD IMPGVVFIPF HYAECAANVL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF04879: 7-62 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF00384: 64-485 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF01568: 571-677 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 103-312 GLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGN ALI: 42-249 PINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR V ENV: 29-252 NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 387-472 QC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQA ALI: 253-338 EDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ENV: 247-392 DR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 610-684 ARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGG ALI: 415-487 QLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMG ENV: 409-506 SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 837-915 ALI: 568-647 E YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYM ENV: 559-653 RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFAD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 100-310 GPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SM ALI: 42-250 PINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VN ENV: 20-264 GCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYAD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 434-464 QYADV ILPGACFAEK DGTFTSGERR INRVRK ALI: 300-330 LTTGTDNVR SMGNLALLTG NVGREGVGVN PL ENV: 256-368 KKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 601-679 SYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS I ALI: 410-485 NHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAK ENV: 391-491 EIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 820-900 ALI: 568-647 E YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYM ENV: 562-675 AEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 127-328 GF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN ALI: 50-249 PKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR V ENV: 39-252 QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 402-481 PVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISE ALI: 253-330 EDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PL ENV: 250-343 NGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 625-700 SRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN ALI: 415-488 QLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF ENV: 383-499 EQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD V Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSENSEIMK YVATTCPYCG VGCTLNLVVS NGKVVGVEPN QRSPINEGKL CPKGVTCWEH IHSPDRLTTP LIKKDGKFIE ASWDEALDLV AKNLKVIYDK HGPKGLGFQT SCRTVNEDCY IFQKFARVGF KTNNVDNCAR ICHGPSVAGL SLSFGSGAAT NGFEDALNAD LILIWGSNAV EAHPLAGRRI AQAKKKGIQI IAVDPRYTMT ARLADTYVRF NPSTHIALAN SMMYWIIKEG LEDKKFIQDR VNGFEDLKKT VENYADAEAI HGVPLDVVKD IAFRYAKAKN AVIIYCLGIT ELTTGTDNVR SMGNLALLTG NVGREGVGVN PLRGQNNVQG ACDMGAYPNV YSGYQKCEVA ENRAKMEKAW SVTNLPDWYG ATLTEQINQC GDEIKGMYIL GLNPVVTYPS SNHVKAQLEK LDFLVVQDIF FTETCQYADV ILPGACFAEK DGTFTSGERR INRVRKAVNP PGQAKEDIHI ISELAAKMGF KGFELPTAKD VWDDMRAVTP SMFGATYEKL ERPEGICWPC PTEEHPGTPI LHREKFATAD GKGNLFGIDY RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLDPMSK MPELKHCAIS IEKVGGN HMM: 840-921 ALI: 568-648 E YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT ENV: 559-664 RPPAEVADAE YPFTLMTGRL IFHYHSRTQT DRAADLHREV PESYAQINIE DARRLGIKNN EYIKLKSRRG ETTTLARVTD EVAPGVVYMT MHFADGVNNL TNTVLD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF04879: 3-57 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00384: 59-485 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF01568: 573-679 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 76-311 WDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QML ALI: 17-239 SL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK R ENV: 3-243 KYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 387-469 EK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP P ALI: 244-330 DELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NN ENV: 239-340 RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 609-685 GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQ ALI: 414-488 HALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY ENV: 409-518 LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 838-918 ALI: 570-652 YPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHY ENV: 559-658 FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 71-309 FVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL Q ALI: 15-240 GCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RC ENV: 6-249 QTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK E Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 395-465 LYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKA ALI: 256-326 SLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALR ENV: 244-351 DELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 611-678 AQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA ALI: 419-484 LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAA ENV: 393-492 KCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 819-901 ALI: 568-652 E EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHY ENV: 553-663 LMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTIN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 127-328 CA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ ALI: 45-240 PKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RC ENV: 37-243 PV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 402-482 PMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASI ALI: 244-326 DELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALR ENV: 239-338 RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 566-700 PDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA ALI: 351-488 IDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY ENV: 341-494 PVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDLKYVQTT CPYCGTGCSL NLVVKDGKVV GTAPYHRSPV NEGKLCPKGT YAHEFINSPD RLTKPLIKKD GKFVEATWDE ALKLIAEKFK SYKPDECACL ASARVSNEDN YAMMKFARGV LKTKHIDHCA RLCHASTVAG LANIFGSGAM TNSIGDIADS KCVFIIGSNT FECHPLIGRR VMQAKAKGAK FIYADPRLTA TGKQADLYLQ FRSGTDVALF NGMMQEIIKN GWEAKDFIEK RCNGFDELKK EVMKDEYSLE NVSSITGVPV DQIKTAAEWV AKSGATAILY SMGITQHTTG VDNVKSVGNL QMLTGNLGRP GTGVNALRGQ NNVQGACDMG CLPVVYTAYQ KVIDEAAQKK FADAWKFPDG IAKGENGYEV TTLMNVLTEK PGEIKCLYIM GENPMISDPD LTHVEHALKT LDFLVVQDIF LNETAEFADV VLPAACYAEK DGTQTSTERR VQMWRKAQDP PGEAKGDWEI IASIAAAMGY GAQFPWKTSE EVFNEMASLT PSYAGMTYER LNRPEALHWP CPTKEHPGTP ILHSEKFGMP DGKGLMTAIP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN MLTINALDPI AKIPESKACA VRVEKIQEA HMM: 841-919 ALI: 570-649 YPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI P ENV: 557-658 IP FKWPVEVPDE EYPYVLTTGR SIWQWHTGTM TRRSVDLERE EPTGWIEINT GDAQKLGIKD KELVKAKTRR GEITITARVT DNIKPGVMFI PFHYVECAAN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF04879: 7-61 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF00384: 63-485 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF01568: 570-676 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 104-312 GFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNL ALI: 42-248 INDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV ENV: 21-251 TLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 387-471 CG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKA ALI: 252-336 EELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQ ENV: 249-367 NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 610-684 RRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN ALI: 414-486 QLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMG ENV: 408-504 S NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 837-894 ALI: 567-625 EY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSR ENV: 558-652 R PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 100-309 PKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS M ALI: 41-248 PINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV ENV: 2-258 ESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 399-464 LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKA ALI: 264-329 AEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP L ENV: 251-371 FEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 594-680 HYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EK ALI: 402-485 VVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKM ENV: 388-490 G DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 820-900 ALI: 567-646 EY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYM ENV: 561-673 AEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 127-330 FK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LR ALI: 49-250 PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NG ENV: 42-269 INDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 402-481 VVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SEL ALI: 252-329 EELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP L ENV: 249-342 NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 627-701 GK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN ALI: 416-488 EKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK ENV: 390-499 EIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV W Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MSESNLVKY VQTTCPYCGV GCTLNLVVKN EKVVGVEPYK RSPINDGKLC PKGLTCWEHI HSPDRLTTPL IKKDGKFVEA SWDEALDLVA KKLKETSDKY GPKAFGFQTS CRTVNEDCYI FQKFARVGFK TNNVDNCARI CHGPSVAGLS LSFGSGAATN GFEDALNSDF ILVWGSNALE AHPLAGRRLV QAKLKGIPIY AVDPRLSTTA KIADKWIQFN PSTHIALANS MMYWIIKADK HDKKFIEERV NGFEELKATV EKYADAEDIH GVPLETVKEL AYKYASAKSA VIIYCLGVTE LTTGTDNVRS MGNLALLTGN VGRPGTGVNP LRGQNNVQGA CDMGAYPNVY SGYQKCEIAE NRAKMEKAWG VTGLPDWYGQ TLTEQINICG DEIKTMYILG LNPVVTYPDS NHVKRQLEKL DFLVVQDIFF TETCQYADVI LPGACFAEKD GTFTSGERRI NRVRKATNPP GKAKEDIWII SELAKKMGLK GFDLPTAKDV WDDMRNCTPS MFGATYEKLE KPESIVWPCP TLEHCGTPIL HCEKFACADG KGNLFGIEYR PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NTVLDPMSKM PELKHCAVKV EKIGGN HMM: 840-916 ALI: 567-644 EY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVL ENV: 558-660 R PPAEVADAEY PFTMMTGRLI FHYHSRTQTD RSAALHYEVP ASYVQINNED ARRLGIGQHE KILITSRRGK TETIAHVTDE IGPGVLYMTM HFNEGVNNLT NT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF04879: 4-55 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00384: 58-483 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF01568: 571-660 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 97-313 LA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGN ALI: 32-240 NIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TR ENV: 9-242 PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 387-469 SS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP V ALI: 243-329 ESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN N ENV: 239-340 TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 605-681 VHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPV ALI: 409-483 HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIAC ENV: 389-495 NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 838-915 ALI: 569-647 YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFM ENV: 555-654 PVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 208-310 F YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM ML ALI: 138-240 L TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TR ENV: 9-248 PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 394-465 MILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAV ALI: 254-325 YTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALR ENV: 241-341 EYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 587-675 MT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPIC ALI: 395-480 ILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TE ENV: 366-488 ENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 821-897 ALI: 569-646 YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIF ENV: 555-655 PVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAAL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 224-329 IIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN N ALI: 135-240 MTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TR ENV: 36-242 PVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 405-482 EPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIA ALI: 246-325 KKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALR ENV: 241-337 EYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 601-696 VYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV ALI: 392-483 KAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIAC ENV: 343-491 FPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MINQVPTIC PYCGTGCSVH LIVQDGKITG TTPNIRSPVN EGKLCPKGTY CHQFIHSPDR LKKPLIRKGD VFVETDWETV YHLIAQKLTT YSADEIGVLA SARCSNEDNY VLMKFARGVL KTNNLDHCAR FCHEATMTGL TLSFGRGVMT NSIPDIGRSD CIFCLGSNTF EQHPLIGRQI VRAQAAGGRF IYADPRYTPT AIQADLFLQF YSGSDVAVLN CIMGEIIRNG LEDKDFIRSR TREYESLKKL VLQNRYTPQE VSILTGVSKT DLIRAAEWIG SADRCTVLYA MGLSHLSGGV HNVRAIANLM MLTGNIGRPG TGVNALRGQN NVQGACDMGC LPDFFPGYKP VTDGNFHQKI ARTWKFPENI APARPGLDMN RMFQKAGESS NRIKAMILVG ENPLVTEPDR HIVEHAIKNL KFLVVSDIFF TKTCEYAHVV LPAACYAEKD GTVTNTERRV QRLRKAVEAP VLAKPDWQII TEIACLMGYE KQFPYQHPSD IFREITTVCE PYQGMTFERV SLPDGICWPC VSADDPGTAI LYSDRFYHPD GKGVFCPVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SLFDAALNRL MGLSESGPGF SEYKPICVSL EPVGGGEV HMM: 840-913 ALI: 568-642 R YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKE ENV: 555-650 PVEW KAPAELPDSR YPFRLTSGRV IWHWHTGTMT RRSKNLTDEL NEVYIEVHPS DAEKVRISDG DMIQVRSRKG ELSCRARVVS DIKEGMIFMP SL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MVLVREGIG CPYCGCSCDD VRITLSDDGK KILDVENACA IGTEIFLHAT NHHRITHPRI RQPDGSFNEI SYEKAIDFVA TAILNAKKPL MYGFGSTTCE AQGAAARLME LGGGVLDNCA SICHGPSLMA FFDNGHPTCT LGEVKNRADV ILYWGANPVH AHPRHMSRYA IYPIGFFTGN GHLRRTVIVV DPRKTDSAGT ADYHLQIEPG MDYELINAFR MVLYGFESDI PEMVAGIPKQ SILEISKVLR EAKFGVCFFG MGLTHTDGRN HNVDIAISLM RDLNAVSKWS IMAMRGHFNI AGPNMVWSWS YGFPYCLDLT KGEHAHMNPG ETSTIDLAIR DEIDLFINIG TDAAAHFPID AVRHLKKHTW ITIDPNMSMA AEIADLHIPV GISGIEVSGI VYRMDNVPIQ YRKVIDMPDG MLSDEEVLNR ISERLEELME SERVKAEVPD ISLQKGISPA PGFTQSLI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460
PF00384: 52-222 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MVLVREGIG CPYCGCSCDD VRITLSDDGK KILDVENACA IGTEIFLHAT NHHRITHPRI RQPDGSFNEI SYEKAIDFVA TAILNAKKPL MYGFGSTTCE AQGAAARLME LGGGVLDNCA SICHGPSLMA FFDNGHPTCT LGEVKNRADV ILYWGANPVH AHPRHMSRYA IYPIGFFTGN GHLRRTVIVV DPRKTDSAGT ADYHLQIEPG MDYELINAFR MVLYGFESDI PEMVAGIPKQ SILEISKVLR EAKFGVCFFG MGLTHTDGRN HNVDIAISLM RDLNAVSKWS IMAMRGHFNI AGPNMVWSWS YGFPYCLDLT KGEHAHMNPG ETSTIDLAIR DEIDLFINIG TDAAAHFPID AVRHLKKHTW ITIDPNMSMA AEIADLHIPV GISGIEVSGI VYRMDNVPIQ YRKVIDMPDG MLSDEEVLNR ISERLEELME SERVKAEVPD ISLQKGISPA PGFTQSLI HMM: 120-294 ICHGPSLMA FFDNGHPTCT LGEVKNRADV ILYWGANPVH AHPRHMSRYA IYPIGFFTGN GHLRRTVIVV DPRKTDSAGT ADYHLQIEPG MDYELINAFR MVLYGFESDI PEMVAGIPKQ SILEISKVLR EAKFGVCFFG MGLTHTDGRN HNVDIAISLM RDLNAVSKWS IMAMRG ALI: 47-218 AT NHHRITHPRI RQPDGSFNEI SYEKAIDFVA TAILNAKKPL MYGFGSTTCE AQGAAARLME LGGGVLDNCA SICHGPSLMA FFDNGHPTCT LGEVKNRADV ILYWGANPVH AHPRHMSRYA IYPIGFFTGN GHLRRTVIVV DPRKTDSAGT ADYHLQIEPG MDYELINAFR ENV: 33-227 VENACA IGTEIFLHAT NHHRITHPRI RQPDGSFNEI SYEKAIDFVA TAILNAKKPL MYGFGSTTCE AQGAAARLME LGGGVLDNCA SICHGPSLMA FFDNGHPTCT LGEVKNRADV ILYWGANPVH AHPRHMSRYA IYPIGFFTGN GHLRRTVIVV DPRKTDSAGT ADYHLQIEPG MDYELINAFR MVLYGFESD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460
Sequence: MVLVREGIG CPYCGCSCDD VRITLSDDGK KILDVENACA IGTEIFLHAT NHHRITHPRI RQPDGSFNEI SYEKAIDFVA TAILNAKKPL MYGFGSTTCE AQGAAARLME LGGGVLDNCA SICHGPSLMA FFDNGHPTCT LGEVKNRADV ILYWGANPVH AHPRHMSRYA IYPIGFFTGN GHLRRTVIVV DPRKTDSAGT ADYHLQIEPG MDYELINAFR MVLYGFESDI PEMVAGIPKQ SILEISKVLR EAKFGVCFFG MGLTHTDGRN HNVDIAISLM RDLNAVSKWS IMAMRGHFNI AGPNMVWSWS YGFPYCLDLT KGEHAHMNPG ETSTIDLAIR DEIDLFINIG TDAAAHFPID AVRHLKKHTW ITIDPNMSMA AEIADLHIPV GISGIEVSGI VYRMDNVPIQ YRKVIDMPDG MLSDEEVLNR ISERLEELME SERVKAEVPD ISLQKGISPA PGFTQSLI HMM: 259-284 MGLTHTDGRN HNVDIAISLM RDLNAV ALI: 366-391 HTW ITIDPNMSMA AEIADLHIPV GIS ENV: 351-410 AAAHFPID AVRHLKKHTW ITIDPNMSMA AEIADLHIPV GISGIEVSGI VYRMDNVPIQ YR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460
Sequence: MAAWVCTKC GYVYDERFGD PEHGIVAGTL FEKIPDTWVC PRCKAAKPFF AKKKV
10 20 30 40 50
PF00301: 3-49 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MAAWVCTKC GYVYDERFGD PEHGIVAGTL FEKIPDTWVC PRCKAAKPFF AKKKV HMM: 426-468 ALI: 4-46 VCTKC GYVYDERFGD PEHGIVAGTL FEKIPDTWVC PRCKAAKP ENV: 1-53 AAWVCTKC GYVYDERFGD PEHGIVAGTL FEKIPDTWVC PRCKAAKPFF AKKKV Position: 10 20 30 40 50
Sequence: MDSYECSIC GYVYDPAKGD PDNGIEPGTA FDDLPDDWLC PLCQEGKEVF EMI
10 20 30 40 50
PF00301: 3-49 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MDSYECSIC GYVYDPAKGD PDNGIEPGTA FDDLPDDWLC PLCQEGKEVF EMI HMM: 425-467 ALI: 3-45 YECSIC GYVYDPAKGD PDNGIEPGTA FDDLPDDWLC PLCQEGK ENV: 1-51 DSYECSIC GYVYDPAKGD PDNGIEPGTA FDDLPDDWLC PLCQEGKEVF EMI Position: 10 20 30 40 50
Sequence: MGDRSVADR LKDFGEVDNG LSPKEAIEEA GRCLQCKKPG CVDGCPVNID IPAFVALIAK GKFLEAAESI RQQNLLPAIC GRVCPQETQC EALCILGKKD TPIRIGQLER FAADQERAKG LTVPARKTAT GKRVAVIGSG PAGIVAAGEL AKDGHDVVLY ESLHAPGGVL TYGIPSFRLP KDVVKAEIDL ILAMGVDLRL NHLVGRTVSF EELEEYDAIL LGTGAGLPYF MGIPGENLSG VYSANEFLTR VNLMHAERFP EYDTPVAKMN RVVVVGGGNV AMDAARTARR MGAQVTLVYR RREEDLPARA AEVHHAKEEG IEFITCANPI RILGEQAVTG IECIRMQMCN LDKSGRPIPE PIDNDTFTLD CDVVIQAIGQ GPNPVLVSQI PGLDKGRAGN VVTEEDGRTS HPKIFAAGDV TTGAATVIMA MGGAKQAARS ICEMLGSR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
PF14691: 9-119 ♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
PF07992: 130-431 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
Sequence: MGDRSVADR LKDFGEVDNG LSPKEAIEEA GRCLQCKKPG CVDGCPVNID IPAFVALIAK GKFLEAAESI RQQNLLPAIC GRVCPQETQC EALCILGKKD TPIRIGQLER FAADQERAKG LTVPARKTAT GKRVAVIGSG PAGIVAAGEL AKDGHDVVLY ESLHAPGGVL TYGIPSFRLP KDVVKAEIDL ILAMGVDLRL NHLVGRTVSF EELEEYDAIL LGTGAGLPYF MGIPGENLSG VYSANEFLTR VNLMHAERFP EYDTPVAKMN RVVVVGGGNV AMDAARTARR MGAQVTLVYR RREEDLPARA AEVHHAKEEG IEFITCANPI RILGEQAVTG IECIRMQMCN LDKSGRPIPE PIDNDTFTLD CDVVIQAIGQ GPNPVLVSQI PGLDKGRAGN VVTEEDGRTS HPKIFAAGDV TTGAATVIMA MGGAKQAARS ICEMLGSR HMM: 171-207 GIPSFRLP KDVVKAEIDL ILAMGVDLRL NHLVGRTVS ALI: 123-159 ARKTAT GKRVAVIGSG PAGIVAAGEL AKDGHDVVLY E ENV: 105-171 QLER FAADQERAKG LTVPARKTAT GKRVAVIGSG PAGIVAAGEL AKDGHDVVLY ESLHAPGGVL TYG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
Sequence: MGDRSVADR LKDFGEVDNG LSPKEAIEEA GRCLQCKKPG CVDGCPVNID IPAFVALIAK GKFLEAAESI RQQNLLPAIC GRVCPQETQC EALCILGKKD TPIRIGQLER FAADQERAKG LTVPARKTAT GKRVAVIGSG PAGIVAAGEL AKDGHDVVLY ESLHAPGGVL TYGIPSFRLP KDVVKAEIDL ILAMGVDLRL NHLVGRTVSF EELEEYDAIL LGTGAGLPYF MGIPGENLSG VYSANEFLTR VNLMHAERFP EYDTPVAKMN RVVVVGGGNV AMDAARTARR MGAQVTLVYR RREEDLPARA AEVHHAKEEG IEFITCANPI RILGEQAVTG IECIRMQMCN LDKSGRPIPE PIDNDTFTLD CDVVIQAIGQ GPNPVLVSQI PGLDKGRAGN VVTEEDGRTS HPKIFAAGDV TTGAATVIMA MGGAKQAARS ICEMLGSR HMM: 161-209 LHAPGGVL TYGIPSFRLP KDVVKAEIDL ILAMGVDLRL NHLVGRTVSF E ALI: 249-299 VNLMHAERFP EYDTPVAKMN RVVVVGGGNV AMDAARTARR MGAQVTLVYR R ENV: 238-311 G VYSANEFLTR VNLMHAERFP EYDTPVAKMN RVVVVGGGNV AMDAARTARR MGAQVTLVYR RREEDLPARA AEV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
Sequence: MPEVTVYST QNCPYCRLAK AFLDRNNIPY RSVDVGIDRK AAKEMVELSG QYGVPVIVAG EEVIVGFDTD KLRALFTTGK KPDMFDVIIV GAGPAGLTAA LYCVRKNLKT LMISPDIGGQ ALESWNIENY MGYRMITGDD LMAKFEEQIR ELEIRIELDQ VNSLLPTSGG FSVKTVSDQE YKGKTIILSQ GKKPRKLGVA REEEFIGRGL SVCATCDGPI FKEKVVGVVG GGNSALTTAL EMSGIAKEVH LIVRSSIRAD AVYTSQYAQK QNIITHTGYE VTELIGDDRL SGIIITNRET GEKKTLKLDG LFTEIGWIPN TSFVEGLLKL NDQKEIVIDI NCRTSAPGIF AAGDVTSIAG KQIIIACGEG AKAALSAFDY LMTQ
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF00462: 3-63 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF07992: 83-358 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MPEVTVYST QNCPYCRLAK AFLDRNNIPY RSVDVGIDRK AAKEMVELSG QYGVPVIVAG EEVIVGFDTD KLRALFTTGK KPDMFDVIIV GAGPAGLTAA LYCVRKNLKT LMISPDIGGQ ALESWNIENY MGYRMITGDD LMAKFEEQIR ELEIRIELDQ VNSLLPTSGG FSVKTVSDQE YKGKTIILSQ GKKPRKLGVA REEEFIGRGL SVCATCDGPI FKEKVVGVVG GGNSALTTAL EMSGIAKEVH LIVRSSIRAD AVYTSQYAQK QNIITHTGYE VTELIGDDRL SGIIITNRET GEKKTLKLDG LFTEIGWIPN TSFVEGLLKL NDQKEIVIDI NCRTSAPGIF AAGDVTSIAG KQIIIACGEG AKAALSAFDY LMTQ HMM: 4-31 TVYST QNCPYCRLAK AFLDRNNIPY RSV ALI: 82-109 MFDVIIV GAGPAGLTAA LYCVRKNLKT L ENV: 79-141 KPDMFDVIIV GAGPAGLTAA LYCVRKNLKT LMISPDIGGQ ALESWNIENY MGYRMITGDD LMA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MPEVTVYST QNCPYCRLAK AFLDRNNIPY RSVDVGIDRK AAKEMVELSG QYGVPVIVAG EEVIVGFDTD KLRALFTTGK KPDMFDVIIV GAGPAGLTAA LYCVRKNLKT LMISPDIGGQ ALESWNIENY MGYRMITGDD LMAKFEEQIR ELEIRIELDQ VNSLLPTSGG FSVKTVSDQE YKGKTIILSQ GKKPRKLGVA REEEFIGRGL SVCATCDGPI FKEKVVGVVG GGNSALTTAL EMSGIAKEVH LIVRSSIRAD AVYTSQYAQK QNIITHTGYE VTELIGDDRL SGIIITNRET GEKKTLKLDG LFTEIGWIPN TSFVEGLLKL NDQKEIVIDI NCRTSAPGIF AAGDVTSIAG KQIIIACGEG AKAALSAFDY LMTQ HMM: 177-212 QE YKGKTIILSQ GKKPRKLGVA REEEFIGRGL SVCA ALI: 221-256 EKVVGVVG GGNSALTTAL EMSGIAKEVH LIVRSSIR ENV: 198-270 A REEEFIGRGL SVCATCDGPI FKEKVVGVVG GGNSALTTAL EMSGIAKEVH LIVRSSIRAD AVYTSQYAQK QN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MPEVTVYST QNCPYCRLAK AFLDRNNIPY RSVDVGIDRK AAKEMVELSG QYGVPVIVAG EEVIVGFDTD KLRALFTTGK KPDMFDVIIV GAGPAGLTAA LYCVRKNLKT LMISPDIGGQ ALESWNIENY MGYRMITGDD LMAKFEEQIR ELEIRIELDQ VNSLLPTSGG FSVKTVSDQE YKGKTIILSQ GKKPRKLGVA REEEFIGRGL SVCATCDGPI FKEKVVGVVG GGNSALTTAL EMSGIAKEVH LIVRSSIRAD AVYTSQYAQK QNIITHTGYE VTELIGDDRL SGIIITNRET GEKKTLKLDG LFTEIGWIPN TSFVEGLLKL NDQKEIVIDI NCRTSAPGIF AAGDVTSIAG KQIIIACGEG AKAALSAFDY LMTQ HMM: 338-386 I NCRTSAPGIF AAGDVTSIAG KQIIIACGEG AKAALSAFDY LMTQ ALI: 271-325 IITHTGYE VTELIGDDRL SGIIITNRET GEKKTLKLDG LFTEIGWIPN TSFVEGL ENV: 260-342 VYTSQYAQK QNIITHTGYE VTELIGDDRL SGIIITNRET GEKKTLKLDG LFTEIGWIPN TSFVEGLLKL NDQKEIVIDI NCRT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MPKVIENVG CPYCGCSCDD VRITVSDDGK DILEVENVCA IGTEIFKHGC SKDRIRLPRM RQPDGSMKDI SYEEAIDWTA RHLLKAKKPL MYGFGSTNCE GQAAAARVME IAGGMLDNCA TICHGPSFLA IFDNGYPSCT LGEVKNRADV IVYWGSNPAH AHPRHMSRYS IFPRGFFTGK GQKKRTVIVI DPRFTDTANV ADYHLQVKQG HDYELFNAFR MVIHGHGKDL PDEVAGIKKE TILEVAEIMK NARFGTTFFG MGLTHTDGRN HNIDIAISLT RDLNKISKWT IMAMRGHYNI AGPGVVWSWT FGFPYCLDLT KQNHAHMNPG ETSSVDMAMR DEVDMFINIG TDAAAHFPIP AVKQLKKHPW VTIDPSINMA SEISDLHIPV CICGVDVGGI VYRMDNVPIQ FRKVIEPPEG VMDDETLLNK IADRMEELKA KGEA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
PF00384: 52-225 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MPKVIENVG CPYCGCSCDD VRITVSDDGK DILEVENVCA IGTEIFKHGC SKDRIRLPRM RQPDGSMKDI SYEEAIDWTA RHLLKAKKPL MYGFGSTNCE GQAAAARVME IAGGMLDNCA TICHGPSFLA IFDNGYPSCT LGEVKNRADV IVYWGSNPAH AHPRHMSRYS IFPRGFFTGK GQKKRTVIVI DPRFTDTANV ADYHLQVKQG HDYELFNAFR MVIHGHGKDL PDEVAGIKKE TILEVAEIMK NARFGTTFFG MGLTHTDGRN HNIDIAISLT RDLNKISKWT IMAMRGHYNI AGPGVVWSWT FGFPYCLDLT KQNHAHMNPG ETSSVDMAMR DEVDMFINIG TDAAAHFPIP AVKQLKKHPW VTIDPSINMA SEISDLHIPV CICGVDVGGI VYRMDNVPIQ FRKVIEPPEG VMDDETLLNK IADRMEELKA KGEA HMM: 273-310 IAISLT RDLNKISKWT IMAMRGHYNI AGPGVVWSWT FG ALI: 181-218 KKRTVIVI DPRFTDTANV ADYHLQVKQG HDYELFNAFR ENV: 147-233 DV IVYWGSNPAH AHPRHMSRYS IFPRGFFTGK GQKKRTVIVI DPRFTDTANV ADYHLQVKQG HDYELFNAFR MVIHGHGKDL PDEVA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
Sequence: MPKVIENVG CPYCGCSCDD VRITVSDDGK DILEVENVCA IGTEIFKHGC SKDRIRLPRM RQPDGSMKDI SYEEAIDWTA RHLLKAKKPL MYGFGSTNCE GQAAAARVME IAGGMLDNCA TICHGPSFLA IFDNGYPSCT LGEVKNRADV IVYWGSNPAH AHPRHMSRYS IFPRGFFTGK GQKKRTVIVI DPRFTDTANV ADYHLQVKQG HDYELFNAFR MVIHGHGKDL PDEVAGIKKE TILEVAEIMK NARFGTTFFG MGLTHTDGRN HNIDIAISLT RDLNKISKWT IMAMRGHYNI AGPGVVWSWT FGFPYCLDLT KQNHAHMNPG ETSSVDMAMR DEVDMFINIG TDAAAHFPIP AVKQLKKHPW VTIDPSINMA SEISDLHIPV CICGVDVGGI VYRMDNVPIQ FRKVIEPPEG VMDDETLLNK IADRMEELKA KGEA HMM: 279-300 RDLNKISKWT IMAMRGHYNI AG ALI: 370-391 TIDPSINMA SEISDLHIPV CIC ENV: 358-397 P AVKQLKKHPW VTIDPSINMA SEISDLHIPV CICGVDVGG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
Sequence: MRTFIEQMR TRGLVTDVHD PVSSRYDAPK RAFSTDRLLF FHNLDGRKAV MNLVATRESL AVALGVAPEI LVPRLASCRY DGKLLDAGSL PMRPVNLDEI PIMENYPGEA GRYLNSGVVF SRYEGVENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL ANGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AGVTGVTDVV LTKGGCGYLH GVVQIKKRTE GDGKNAIMAA FAAHTSLKHV VIVDGDINPG NPSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEEEFVRA VWED
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
PF01977: 4-374 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MRTFIEQMR TRGLVTDVHD PVSSRYDAPK RAFSTDRLLF FHNLDGRKAV MNLVATRESL AVALGVAPEI LVPRLASCRY DGKLLDAGSL PMRPVNLDEI PIMENYPGEA GRYLNSGVVF SRYEGVENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL ANGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AGVTGVTDVV LTKGGCGYLH GVVQIKKRTE GDGKNAIMAA FAAHTSLKHV VIVDGDINPG NPSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEEEFVRA VWED HMM: 118-409 F SRYEGVENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL ANGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AGVTGVTDVV LTKGGCGYLH GVVQIKKRTE GDGKNAIMAA FAAHTSLKHV VIVDGDINPG NPSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEEEFVRA V ALI: 94-374 NLDEI PIMENYPGEA GRYLNSGVVF SRYEGVENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL ANGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AGVTGVTDVV LTKGGCGYLH GVVQIKKRTE GDGKNAIMAA FAAHTSLKHV VIVDGDINPG NPSDVEFAIA TRVRADRDTL IIPGVR ENV: 90-396 MRPVNLDEI PIMENYPGEA GRYLNSGVVF SRYEGVENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL ANGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AGVTGVTDVV LTKGGCGYLH GVVQIKKRTE GDGKNAIMAA FAAHTSLKHV VIVDGDINPG NPSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDAT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MRTFIEQMR TRGLVTDVHD PVSSRYDAPK RAFSTDRLLF FHNLDGRKAV MNLVATRESL AVALGVAPEI LVPRLASCRY DGKLLDAGSL PMRPVNLDEI PIMENYPGEA GRYLNSGVVF SRYEGVENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL ANGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AGVTGVTDVV LTKGGCGYLH GVVQIKKRTE GDGKNAIMAA FAAHTSLKHV VIVDGDINPG NPSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEEEFVRA VWED HMM: 187-279 SM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA P ALI: 160-248 NGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV ENV: 91-382 RPVNLDEI PIMENYPGEA GRYLNSGVVF SRYEGVENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL ANGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AGVTGVTDVV LTKGGCGYLH GVVQIKKRTE GDGKNAIMAA FAAHTSLKHV VIVDGDINPG NPSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MRTFIEQMR TRGLVTDVHD PVSSRYDAPK RAFSTDRLLF FHNLDGRKAV MNLVATRESL AVALGVAPEI LVPRLASCRY DGKLLDAGSL PMRPVNLDEI PIMENYPGEA GRYLNSGVVF SRYEGVENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL ANGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AGVTGVTDVV LTKGGCGYLH GVVQIKKRTE GDGKNAIMAA FAAHTSLKHV VIVDGDINPG NPSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEEEFVRA VWED HMM: 132-456 MLKAGKD RLVARLVEGR HTHTLHKKAL ANGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AGVTGVTDVV LTKGGCGYLH GVVQIKKRTE GDGKNAIMAA FAAHTSLKHV VIVDGDINPG NPSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEEEFVRA VWED ALI: 95-409 LDEI PIMENYPGEA GRYLNSGVVF SRYEGVENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL ANGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AGVTGVTDVV LTKGGCGYLH GVVQIKKRTE GDGKNAIMAA FAAHTSLKHV VIVDGDINPG NPSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEEEFVRA V ENV: 89-413 PMRPVNLDEI PIMENYPGEA GRYLNSGVVF SRYEGVENAS VHRMLKAGKD RLVARLVEGR HTHTLHKKAL ANGERLPVAI VIGMHPLVLF ASCSRVPESM ELPFAAELLG GEMPVYTLSN GVRVPDAEII LEGYIGNETA VEGPYVDITR TYDPERVQPV IELTGMYTKP DFIYHGLVNA GDEHKLLMGA PYEPLIYRSV AGVTGVTDVV LTKGGCGYLH GVVQIKKRTE GDGKNAIMAA FAAHTSLKHV VIVDGDINPG NPSDVEFAIA TRVRADRDTL IIPGVRGSSL DPSRIGDGLN VKMGIDATME LGKEEEFVRA VWED Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MAEENKKEI ELEISGMHCA TCAVTVEKSL SSTPGVMESK VNLATGKARV LYDPSQVSVS DLTGAVEKSG FSVKFEKAVI KVGGMTCASC VQTVQKALQT LDGVISADVN LSNERAYITY NPSLVDIKKI RDVIDNAGYQ FLGTDRDEID ESEKLLEIQL KKQFFKIIIG FSLSLVLMGM MYIPDHDMHL MSYVQFLITT PVLFWLGTPI FRAAFGALRN KTLNMDVMYA MGISVAYLAS VLGTFSIILD MNMLFYETAL MLTAFLSLGR YLEARAKGRT SSAITSLIGL QADSASVIRD GVEIDIPVQE VIPGDIIRMR PGGRIPVDGI VVSGSSYVDE SMVTGEPLAV LREPGQEVIG GTLVTNGAFI YKATRVGSDT MLARIIRLVE EAQGSRPPVQ RLADYAVTWF IPVVLLIAFL AFLYWYGIRG MDLRFSLQTL IAVLVVACPC ALGLATPTAV TVGIGRGAEL GILIRNGSVL EIADKITVAL FDKTGTITKG KPVVTDVDSF IGNPRLLLSM AASLEILSDH PISSAILAKA HHEGIEPAEV TSFQNISGSG LSGTISGGVV RLGTRDFIVS EGISFVSNEE ELVTRREREG KTTILISRDD QILGLISIAD QVKPEAERAV RLLKEMGIRS GMVTGDNQIT ADAVASMVGI TDIFARVLPE GKEDQVIQIQ NNGNVVAFIG DGINDAPALA RADTGIAIGS GTDIAIESAD VVLVRDSLIH IPAALQLARK VMGRIRLNLF WAFAYNIVLI PLAAGILYPV ITFRPEYGAL AMAFSSVTVI SLSLLLKQYT PPALMQEMKS GMYMNKEIDP ICGMSVDPNT AQFKSTYEGK TYYFCNKGCK DTFDKNPEQY KK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860
PF00403: 77-139 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
PF00122: 288-467 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00702: 484-702 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF04945: 816-860 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
Sequence: MAEENKKEI ELEISGMHCA TCAVTVEKSL SSTPGVMESK VNLATGKARV LYDPSQVSVS DLTGAVEKSG FSVKFEKAVI KVGGMTCASC VQTVQKALQT LDGVISADVN LSNERAYITY NPSLVDIKKI RDVIDNAGYQ FLGTDRDEID ESEKLLEIQL KKQFFKIIIG FSLSLVLMGM MYIPDHDMHL MSYVQFLITT PVLFWLGTPI FRAAFGALRN KTLNMDVMYA MGISVAYLAS VLGTFSIILD MNMLFYETAL MLTAFLSLGR YLEARAKGRT SSAITSLIGL QADSASVIRD GVEIDIPVQE VIPGDIIRMR PGGRIPVDGI VVSGSSYVDE SMVTGEPLAV LREPGQEVIG GTLVTNGAFI YKATRVGSDT MLARIIRLVE EAQGSRPPVQ RLADYAVTWF IPVVLLIAFL AFLYWYGIRG MDLRFSLQTL IAVLVVACPC ALGLATPTAV TVGIGRGAEL GILIRNGSVL EIADKITVAL FDKTGTITKG KPVVTDVDSF IGNPRLLLSM AASLEILSDH PISSAILAKA HHEGIEPAEV TSFQNISGSG LSGTISGGVV RLGTRDFIVS EGISFVSNEE ELVTRREREG KTTILISRDD QILGLISIAD QVKPEAERAV RLLKEMGIRS GMVTGDNQIT ADAVASMVGI TDIFARVLPE GKEDQVIQIQ NNGNVVAFIG DGINDAPALA RADTGIAIGS GTDIAIESAD VVLVRDSLIH IPAALQLARK VMGRIRLNLF WAFAYNIVLI PLAAGILYPV ITFRPEYGAL AMAFSSVTVI SLSLLLKQYT PPALMQEMKS GMYMNKEIDP ICGMSVDPNT AQFKSTYEGK TYYFCNKGCK DTFDKNPEQY KK HMM: 413-445 LLIAFL AFLYWYGIRG MDLRFSLQTL IAVLVVA ALI: 828-860 T AQFKSTYEGK TYYFCNKGCK DTFDKNPEQY KK ENV: 811-861 YMNKEIDP ICGMSVDPNT AQFKSTYEGK TYYFCNKGCK DTFDKNPEQY KK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860
Sequence: MAEENKKEI ELEISGMHCA TCAVTVEKSL SSTPGVMESK VNLATGKARV LYDPSQVSVS DLTGAVEKSG FSVKFEKAVI KVGGMTCASC VQTVQKALQT LDGVISADVN LSNERAYITY NPSLVDIKKI RDVIDNAGYQ FLGTDRDEID ESEKLLEIQL KKQFFKIIIG FSLSLVLMGM MYIPDHDMHL MSYVQFLITT PVLFWLGTPI FRAAFGALRN KTLNMDVMYA MGISVAYLAS VLGTFSIILD MNMLFYETAL MLTAFLSLGR YLEARAKGRT SSAITSLIGL QADSASVIRD GVEIDIPVQE VIPGDIIRMR PGGRIPVDGI VVSGSSYVDE SMVTGEPLAV LREPGQEVIG GTLVTNGAFI YKATRVGSDT MLARIIRLVE EAQGSRPPVQ RLADYAVTWF IPVVLLIAFL AFLYWYGIRG MDLRFSLQTL IAVLVVACPC ALGLATPTAV TVGIGRGAEL GILIRNGSVL EIADKITVAL FDKTGTITKG KPVVTDVDSF IGNPRLLLSM AASLEILSDH PISSAILAKA HHEGIEPAEV TSFQNISGSG LSGTISGGVV RLGTRDFIVS EGISFVSNEE ELVTRREREG KTTILISRDD QILGLISIAD QVKPEAERAV RLLKEMGIRS GMVTGDNQIT ADAVASMVGI TDIFARVLPE GKEDQVIQIQ NNGNVVAFIG DGINDAPALA RADTGIAIGS GTDIAIESAD VVLVRDSLIH IPAALQLARK VMGRIRLNLF WAFAYNIVLI PLAAGILYPV ITFRPEYGAL AMAFSSVTVI SLSLLLKQYT PPALMQEMKS GMYMNKEIDP ICGMSVDPNT AQFKSTYEGK TYYFCNKGCK DTFDKNPEQY KK HMM: 422-450 YWYGIRG MDLRFSLQTL IAVLVVACPC AL ALI: 832-860 KSTYEGK TYYFCNKGCK DTFDKNPEQY KK ENV: 817-861 DP ICGMSVDPNT AQFKSTYEGK TYYFCNKGCK DTFDKNPEQY KK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860
Sequence: MTQPTKRME IGISTFLDAS PDPVTGVAIS HAERMRRSVE EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP LPVWIASGGT PESAVRAGTL GLPITFAIIG GMPERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP STHAAMNKLG RERGWPPYTR DSFDAARSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARMEGN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF00296: 7-313 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌
Sequence: MTQPTKRME IGISTFLDAS PDPVTGVAIS HAERMRRSVE EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP LPVWIASGGT PESAVRAGTL GLPITFAIIG GMPERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP STHAAMNKLG RERGWPPYTR DSFDAARSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARMEGN HMM: 370-399 ALI: 289-318 GALYVGDPEY VAEKIVLLRK NLGLDRFFLH ENV: 278-327 R DSFDAARSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MTQPTKRME IGISTFLDAS PDPVTGVAIS HAERMRRSVE EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP LPVWIASGGT PESAVRAGTL GLPITFAIIG GMPERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP STHAAMNKLG RERGWPPYTR DSFDAARSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARMEGN HMM: 53-131 IGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYS ALI: 39-113 EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAE ENV: 28-125 S HAERMRRSVE EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MTQPTKRME IGISTFLDAS PDPVTGVAIS HAERMRRSVE EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP LPVWIASGGT PESAVRAGTL GLPITFAIIG GMPERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP STHAAMNKLG RERGWPPYTR DSFDAARSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARMEGN HMM: 251-297 QAAELYYP STHAAMNKLG RERGWPPYTR DSFDAARSLR GALYVGDPE ALI: 211-257 PERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYY ENV: 204-274 FAIIG GMPERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP STHAAMNKLG RERGWP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MTQPTKRME IGISTFLDAS PDPVTGVAIS HAERMRRSVE EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP LPVWIASGGT PESAVRAGTL GLPITFAIIG GMPERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP STHAAMNKLG RERGWPPYTR DSFDAARSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARMEGN HMM: 65-120 SPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GS ALI: 57-113 HR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAE ENV: 30-121 AERMRRSVE EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MTQPTKRME IGISTFLDAS PDPVTGVAIS HAERMRRSVE EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP LPVWIASGGT PESAVRAGTL GLPITFAIIG GMPERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP STHAAMNKLG RERGWPPYTR DSFDAARSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARMEGN HMM: 250-286 EQAAELYYP STHAAMNKLG RERGWPPYTR DSFDAARS ALI: 222-258 KEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP ENV: 212-271 ERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP STHAAMNKLG RER Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MTQPTKRME IGISTFLDAS PDPVTGVAIS HAERMRRSVE EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP LPVWIASGGT PESAVRAGTL GLPITFAIIG GMPERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP STHAAMNKLG RERGWPPYTR DSFDAARSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARMEGN HMM: 362-392 ALI: 292-322 YVGDPEY VAEKIVLLRK NLGLDRFFLH VDYG ENV: 285-337 RSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MTQPTKRME IGISTFLDAS PDPVTGVAIS HAERMRRSVE EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP LPVWIASGGT PESAVRAGTL GLPITFAIIG GMPERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP STHAAMNKLG RERGWPPYTR DSFDAARSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARMEGN HMM: 74-183 ASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP LPVWI ALI: 70-179 LAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP L ENV: 63-252 ASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP LPVWIASGGT PESAVRAGTL GLPITFAIIG GMPERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MTQPTKRME IGISTFLDAS PDPVTGVAIS HAERMRRSVE EIVLADQVGL DVYGIGEHHR ANYAASSPAV ILAAAASMTK HIRLSSAVTV LSSADPVRVY QDFATLDGLS NGRAEIMAGR GSFIESFPLF GYSLEDYDEL FEEHLELLLA VRASEKVSWR GGHRPAIDNL GVYPRAVQDP LPVWIASGGT PESAVRAGTL GLPITFAIIG GMPERFAPLV SLYKEAAARA GHDPSKLQIA SHSHGFIGDT NEQAAELYYP STHAAMNKLG RERGWPPYTR DSFDAARSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARMEGN HMM: 317-367 LH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARMEGN ALI: 293-351 VGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARM ENV: 285-354 RSLR GALYVGDPEY VAEKIVLLRK NLGLDRFFLH VDYGSLPHSE MLRTIEYLGT KVAPIVHKEI ARMEGN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MTKKKQLKL GALLHGVGGG TSLWRHPDVD PGASVNFELY KSWVHKAEQG KLDLIFIADG LYINEKSIPH FLNRFEPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADGFMLA AAVPRGLEDF VELVVPILQE RGIFRTEYES DTLRGNLGLP IPENQYTRAR AAAEAEGVRS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
PF00296: 20-382 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
Sequence: MTKKKQLKL GALLHGVGGG TSLWRHPDVD PGASVNFELY KSWVHKAEQG KLDLIFIADG LYINEKSIPH FLNRFEPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADGFMLA AAVPRGLEDF VELVVPILQE RGIFRTEYES DTLRGNLGLP IPENQYTRAR AAAEAEGVRS HMM: 2-439 KKKQLKL GALLHGVGGG TSLWRHPDVD PGASVNFELY KSWVHKAEQG KLDLIFIADG LYINEKSIPH FLNRFEPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADGFMLA AAVPRGLEDF VELVVPILQE RGIFRTEYES DTLRGNLGLP IPENQYTRAR A ALI: 3-438 KKQLKL GALLHGVGGG TSLWRHPDVD PGASVNFELY KSWVHKAEQG KLDLIFIADG LYINEKSIPH FLNRFEPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADGFMLA AAVPRGLEDF VELVVPILQE RGIFRTEYES DTLRGNLGLP IPENQYTRAR ENV: 2-441 KKKQLKL GALLHGVGGG TSLWRHPDVD PGASVNFELY KSWVHKAEQG KLDLIFIADG LYINEKSIPH FLNRFEPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADGFMLA AAVPRGLEDF VELVVPILQE RGIFRTEYES DTLRGNLGLP IPENQYTRAR AAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
Sequence: MTKKKQLKL GALLHGVGGG TSLWRHPDVD PGASVNFELY KSWVHKAEQG KLDLIFIADG LYINEKSIPH FLNRFEPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADGFMLA AAVPRGLEDF VELVVPILQE RGIFRTEYES DTLRGNLGLP IPENQYTRAR AAAEAEGVRS HMM: 74-338 EPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK ALI: 79-384 LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADG ENV: 72-415 RFEPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADGFMLA AAVPRGLEDF VELVVPILQE RGIFRTE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
Sequence: MTKKKQLKL GALLHGVGGG TSLWRHPDVD PGASVNFELY KSWVHKAEQG KLDLIFIADG LYINEKSIPH FLNRFEPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADGFMLA AAVPRGLEDF VELVVPILQE RGIFRTEYES DTLRGNLGLP IPENQYTRAR AAAEAEGVRS HMM: 20-438 SLWRHPDVD PGASVNFELY KSWVHKAEQG KLDLIFIADG LYINEKSIPH FLNRFEPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADGFMLA AAVPRGLEDF VELVVPILQE RGIFRTEYES DTLRGNLGLP IPENQYTRAR ALI: 20-426 SLWRHPDVD PGASVNFELY KSWVHKAEQG KLDLIFIADG LYINEKSIPH FLNRFEPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADGFMLA AAVPRGLEDF VELVVPILQE RGIFRTEYES DTLRGNLG ENV: 1-446 TKKKQLKL GALLHGVGGG TSLWRHPDVD PGASVNFELY KSWVHKAEQG KLDLIFIADG LYINEKSIPH FLNRFEPLTL LSALASISSN IGLVGTLSTS YSEPFTVARQ FGSLDVLSGG RAGWNVVTSP LEGSALNYSK KEHPEHDKRY KIATEYLEVT RGLWDSWEDD AFIRDKEKGI FFDPDKVHTL NHEGEFFSVK GPLNIARSKQ GGPVIFQAGA SEVGKNYAAK EADAIFTGAE NLEEAIQFAQ DVKARAASFG RNPDDVLIFP GIGPIIGSTE EEAERKYQEV ASLVTIENAL NYLGRFFEHH DFSQYPLDEP FPELGDLGKN SFQSGTDMIK KDAKEKGLTL RQVALQSATP RTSFIGTAEQ VADRVQEWFE AGAADGFMLA AAVPRGLEDF VELVVPILQE RGIFRTEYES DTLRGNLGLP IPENQYTRAR AAAEAEGV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440
Sequence: MKVALFSLM MNIPNAVTGE SWTAQQKFRN VIRQAVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PFVSLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREAAVPTE AS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
PF00296: 11-304 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌
Sequence: MKVALFSLM MNIPNAVTGE SWTAQQKFRN VIRQAVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PFVSLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREAAVPTE AS HMM: 66-119 IAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY P ALI: 51-105 GAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRL ENV: 25-111 KFRN VIRQAVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MKVALFSLM MNIPNAVTGE SWTAQQKFRN VIRQAVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PFVSLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREAAVPTE AS HMM: 207-286 YK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PFVSLEDVIA NGPALIGS ALI: 168-252 Y QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRP ENV: 149-262 TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTES Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MKVALFSLM MNIPNAVTGE SWTAQQKFRN VIRQAVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PFVSLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREAAVPTE AS HMM: 363-412 ALI: 284-337 IGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREI ENV: 279-359 NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREAAVPTE A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MKVALFSLM MNIPNAVTGE SWTAQQKFRN VIRQAVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PFVSLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREAAVPTE AS HMM: 48-232 E RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGA ALI: 33-225 AVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDP ENV: 9-269 MNIPNAVTGE SWTAQQKFRN VIRQAVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS P Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MKVALFSLM MNIPNAVTGE SWTAQQKFRN VIRQAVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PFVSLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREAAVPTE AS HMM: 312-368 GLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREAAVPTE AS ALI: 279-341 NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STV ENV: 267-344 QS PFVSLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MKVALFSLM MNIPNAVTGE SWTAQQKFRN VIRQAVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PFVSLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREAAVPTE AS HMM: 81-135 VLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAER ALI: 55-110 LSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IG ENV: 42-147 DAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEED Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MKVALFSLM MNIPNAVTGE SWTAQQKFRN VIRQAVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PFVSLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREAAVPTE AS HMM: 217-307 RL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PFVSLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLS ALI: 168-261 Y QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTE ENV: 147-270 DV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MKVALFSLM MNIPNAVTGE SWTAQQKFRN VIRQAVLAEK LGFDAYGVGE RHGAPFLSSS PPVVLTAIAA QTSRIRLLTT VTVLSVLDPV RVAEDYATLD HLSGGRLEMI IGKGNDPRHY PLFGITEEEQ WESLAERYGL LRRLWSEEDV TWSGRYRPPI EGVTTYPRPY QKPIPVWHGS ASSTLSTELA AKYGEPIFSS NSFHPQAKYK ALIDHYRERL AYYGHDPARA VVGAGSGSLY LGTTGEEAIR RYRPYYNAFS VTESSKHNQS PFVSLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREAAVPTE AS HMM: 372-421 ALI: 282-336 ALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQRE ENV: 272-353 SLEDVIA NGPALIGSPD QVIEKILDYQ EAFGHQVLSI SVDGLTESEQ EEQLQRFAEE VLPVLQREIK STVWQDPAVK EDREA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MNMKDNGVE PTFEFGLYTL GDLSPDIQTG KPIHPAQRLR DIVEAAKLAD EAGIDVFGVG EHHRLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLES TTLTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ TVNAKA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
PF00296: 14-318 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MNMKDNGVE PTFEFGLYTL GDLSPDIQTG KPIHPAQRLR DIVEAAKLAD EAGIDVFGVG EHHRLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLES TTLTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ TVNAKA HMM: 74-120 LAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI IS ALI: 70-117 PPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAE ENV: 36-121 RLR DIVEAAKLAD EAGIDVFGVG EHHRLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MNMKDNGVE PTFEFGLYTL GDLSPDIQTG KPIHPAQRLR DIVEAAKLAD EAGIDVFGVG EHHRLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLES TTLTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ TVNAKA HMM: 244-285 TSHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLES TTLTREA ALI: 220-261 HIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFY ENV: 176-268 PRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MNMKDNGVE PTFEFGLYTL GDLSPDIQTG KPIHPAQRLR DIVEAAKLAD EAGIDVFGVG EHHRLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLES TTLTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ TVNAKA HMM: 348-374 I VRRELRKQSQ TVNAKA ALI: 284-309 EAFEQ LAGPETALAV GSPERIAEKI L ENV: 275-316 RLES TTLTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MNMKDNGVE PTFEFGLYTL GDLSPDIQTG KPIHPAQRLR DIVEAAKLAD EAGIDVFGVG EHHRLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLES TTLTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ TVNAKA HMM: 74-188 LAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG ALI: 74-189 LAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG V ENV: 63-263 LDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MNMKDNGVE PTFEFGLYTL GDLSPDIQTG KPIHPAQRLR DIVEAAKLAD EAGIDVFGVG EHHRLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLES TTLTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ TVNAKA HMM: 310-369 TQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ TVNAKA ALI: 290-358 AGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ ENV: 281-360 LTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ TV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MNMKDNGVE PTFEFGLYTL GDLSPDIQTG KPIHPAQRLR DIVEAAKLAD EAGIDVFGVG EHHRLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLES TTLTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ TVNAKA HMM: 77-131 IA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPL ALI: 62-117 RLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAE ENV: 35-121 QRLR DIVEAAKLAD EAGIDVFGVG EHHRLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MNMKDNGVE PTFEFGLYTL GDLSPDIQTG KPIHPAQRLR DIVEAAKLAD EAGIDVFGVG EHHRLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLES TTLTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ TVNAKA HMM: 245-305 SHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLES TTLTREAFEQ LAGPETALAV GSPERIA ALI: 209-269 AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT A ENV: 126-277 LES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MNMKDNGVE PTFEFGLYTL GDLSPDIQTG KPIHPAQRLR DIVEAAKLAD EAGIDVFGVG EHHRLDFALS SPPVVLAAIA QATKHIRLTS ATTVLSTADP VRVFEDFATL DLLSNGRAEI ISGRGAFLES FPLFGYARED YHALFQENLT LLQELNRQAK VTWKGAFRSD LEGAEIAPRP VQPEIPLWIG VGGTPASAAL AGTYGTGMAL AILGGDPSKL QHIVETYRQA GEKAGHDPRH LQVGITSHGY IAKTTEQAMS EFYPYYANYT AQFNGNRLES TTLTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRVAKAI ELLATEVAPI VRRELRKQSQ TVNAKA HMM: 359-389 TVNAKA ALI: 284-313 EAFEQ LAGPETALAV GSPERIAEKI LTQHQ ENV: 268-334 T AQFNGNRLES TTLTREAFEQ LAGPETALAV GSPERIAEKI LTQHQLFGHT RYMMQMDIGG VPFNRV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MEIGITSFV ETKPDVHTGE VISHAQRLRE VVEEIVLADQ VGLDVFGVGE HHRADYAASS PAVVLAAAAA QTRQIRLTSA VTVLSSLDPV RVFQDFATLD GISNGRAEIM AGRGSFIESF PLFGYDLNDY AELYEEHLEL LLKIRASEKV TWKGGHRPSI NNLGVYPRPV QDSIPIWVGS GGRQESAIRA GLLGLPLMLA IIGGSPTDFA PLVQLYQKAA AHAGHDASRL KVGSHSIGFV GENTEAAADT FFPSTMAGMN RLGKERGWGH YDRSSYDAAR SFEGALYVGD PDIVAQKIIH LRKHVGVTRF MLYVPLSTMP HDQVMRAIEL LGTEVAPRVR EEVTKWEAEQ GLDHDSIGI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF00296: 0-302 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
Sequence: MEIGITSFV ETKPDVHTGE VISHAQRLRE VVEEIVLADQ VGLDVFGVGE HHRADYAASS PAVVLAAAAA QTRQIRLTSA VTVLSSLDPV RVFQDFATLD GISNGRAEIM AGRGSFIESF PLFGYDLNDY AELYEEHLEL LLKIRASEKV TWKGGHRPSI NNLGVYPRPV QDSIPIWVGS GGRQESAIRA GLLGLPLMLA IIGGSPTDFA PLVQLYQKAA AHAGHDASRL KVGSHSIGFV GENTEAAADT FFPSTMAGMN RLGKERGWGH YDRSSYDAAR SFEGALYVGD PDIVAQKIIH LRKHVGVTRF MLYVPLSTMP HDQVMRAIEL LGTEVAPRVR EEVTKWEAEQ GLDHDSIGI HMM: 65-120 AAAA QTRQIRLTSA VTVLSSLDPV RVFQDFATLD GISNGRAEIM AGRGSFIESF PL ALI: 50-106 HRADYAASS PAVVLAAAAA QTRQIRLTSA VTVLSSLDPV RVFQDFATLD GISNGRAE ENV: 9-115 ETKPDVHTGE VISHAQRLRE VVEEIVLADQ VGLDVFGVGE HHRADYAASS PAVVLAAAAA QTRQIRLTSA VTVLSSLDPV RVFQDFATLD GISNGRAEIM AGRGSFI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MEIGITSFV ETKPDVHTGE VISHAQRLRE VVEEIVLADQ VGLDVFGVGE HHRADYAASS PAVVLAAAAA QTRQIRLTSA VTVLSSLDPV RVFQDFATLD GISNGRAEIM AGRGSFIESF PLFGYDLNDY AELYEEHLEL LLKIRASEKV TWKGGHRPSI NNLGVYPRPV QDSIPIWVGS GGRQESAIRA GLLGLPLMLA IIGGSPTDFA PLVQLYQKAA AHAGHDASRL KVGSHSIGFV GENTEAAADT FFPSTMAGMN RLGKERGWGH YDRSSYDAAR SFEGALYVGD PDIVAQKIIH LRKHVGVTRF MLYVPLSTMP HDQVMRAIEL LGTEVAPRVR EEVTKWEAEQ GLDHDSIGI HMM: 73-189 IRLTSA VTVLSSLDPV RVFQDFATLD GISNGRAEIM AGRGSFIESF PLFGYDLNDY AELYEEHLEL LLKIRASEKV TWKGGHRPSI NNLGVYPRPV QDSIPIWVGS GGRQESAIRA G ALI: 62-179 VLAAAAA QTRQIRLTSA VTVLSSLDPV RVFQDFATLD GISNGRAEIM AGRGSFIESF PLFGYDLNDY AELYEEHLEL LLKIRASEKV TWKGGHRPSI NNLGVYPRPV QDSIPIWVGS G ENV: 56-191 ASS PAVVLAAAAA QTRQIRLTSA VTVLSSLDPV RVFQDFATLD GISNGRAEIM AGRGSFIESF PLFGYDLNDY AELYEEHLEL LLKIRASEKV TWKGGHRPSI NNLGVYPRPV QDSIPIWVGS GGRQESAIRA GLL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MEIGITSFV ETKPDVHTGE VISHAQRLRE VVEEIVLADQ VGLDVFGVGE HHRADYAASS PAVVLAAAAA QTRQIRLTSA VTVLSSLDPV RVFQDFATLD GISNGRAEIM AGRGSFIESF PLFGYDLNDY AELYEEHLEL LLKIRASEKV TWKGGHRPSI NNLGVYPRPV QDSIPIWVGS GGRQESAIRA GLLGLPLMLA IIGGSPTDFA PLVQLYQKAA AHAGHDASRL KVGSHSIGFV GENTEAAADT FFPSTMAGMN RLGKERGWGH YDRSSYDAAR SFEGALYVGD PDIVAQKIIH LRKHVGVTRF MLYVPLSTMP HDQVMRAIEL LGTEVAPRVR EEVTKWEAEQ GLDHDSIGI HMM: 317-367 MP HDQVMRAIEL LGTEVAPRVR EEVTKWEAEQ GLDHDSIGI ALI: 286-344 VGD PDIVAQKIIH LRKHVGVTRF MLYVPLSTMP HDQVMRAIEL LGTEVAPRVR EEVTKW ENV: 279-348 SFEGALYVGD PDIVAQKIIH LRKHVGVTRF MLYVPLSTMP HDQVMRAIEL LGTEVAPRVR EEVTKWEAEQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MFEYHQTYQ RTFREGELTL GLHIPLENYN METPTMARQI ELAQAAETYG FTTLWLRDVI LDDPNFGDPA VGQIYDILIY GTHLLSQTKQ IALGTSALVL PLRHPLRLAK EVATIEALFP ERLIMGVSSG DRRADFKGLG VDHPSRGAQF REALSYLEKA LYESFPSIDS RYGVIEQATL VPKLKQKIPT LITGFAQQDL DWIGLNGDGW MYYPQAPGRQ IDAIHAWRES ASRQNQSVFR PFSMPMHLDL AEDPDEYATP IRLGFRVGRN KLIELLHLYR KIGVNHLFFA LFDSPRPADE VIHELGEYVL QHFPPHKISV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310
PF00296: 21-236 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
Sequence: MFEYHQTYQ RTFREGELTL GLHIPLENYN METPTMARQI ELAQAAETYG FTTLWLRDVI LDDPNFGDPA VGQIYDILIY GTHLLSQTKQ IALGTSALVL PLRHPLRLAK EVATIEALFP ERLIMGVSSG DRRADFKGLG VDHPSRGAQF REALSYLEKA LYESFPSIDS RYGVIEQATL VPKLKQKIPT LITGFAQQDL DWIGLNGDGW MYYPQAPGRQ IDAIHAWRES ASRQNQSVFR PFSMPMHLDL AEDPDEYATP IRLGFRVGRN KLIELLHLYR KIGVNHLFFA LFDSPRPADE VIHELGEYVL QHFPPHKISV HMM: 39-228 ELAQAAETYG FTTLWLRDVI LDDPNFGDPA VGQIYDILIY GTHLLSQTKQ IALGTSALVL PLRHPLRLAK EVATIEALFP ERLIMGVSSG DRRADFKGLG VDHPSRGAQF REALSYLEKA LYESFPSIDS RYGVIEQATL VPKLKQKIPT LITGFAQQDL DWIGLNGDGW MYYPQAPGRQ IDAIHAWRES ALI: 32-232 PTMARQI ELAQAAETYG FTTLWLRDVI LDDPNFGDPA VGQIYDILIY GTHLLSQTKQ IALGTSALVL PLRHPLRLAK EVATIEALFP ERLIMGVSSG DRRADFKGLG VDHPSRGAQF REALSYLEKA LYESFPSIDS RYGVIEQATL VPKLKQKIPT LITGFAQQDL DWIGLNGDGW MYYPQAPGRQ IDAIHAWRES ASRQ ENV: 25-252 ENYN METPTMARQI ELAQAAETYG FTTLWLRDVI LDDPNFGDPA VGQIYDILIY GTHLLSQTKQ IALGTSALVL PLRHPLRLAK EVATIEALFP ERLIMGVSSG DRRADFKGLG VDHPSRGAQF REALSYLEKA LYESFPSIDS RYGVIEQATL VPKLKQKIPT LITGFAQQDL DWIGLNGDGW MYYPQAPGRQ IDAIHAWRES ASRQNQSVFR PFSMPMHLDL AEDP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310
Sequence: MIIEDAVLR REWLVACRTD ELQEKPLGVM LMGERVVLFR NEEGIHAFKD LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL PADRAIPGKA RTFKYACKEE YGLVWVCLDS EQPAPMFALP EWTDESYRNV MWGSTTVEAK PPRVIENFLD VGHLAVVHEG YLGVSTHTII GDYHVIYDEH SIRSEEIEVF QPDPDGSGQA KNVYYTYEIL RPMTVKFTKR DKETDNKMSI VLTVAPKDAE TTIAYGILSF NYPMDLSDQE IAAFQDVIFA QDKPVVENQK PEDLPLDLQA ELSLACDRMS IAYRRYLKDS GLVWGTA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
PF00355: 10-89 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
PF19112: 145-317 ◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MIIEDAVLR REWLVACRTD ELQEKPLGVM LMGERVVLFR NEEGIHAFKD LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL PADRAIPGKA RTFKYACKEE YGLVWVCLDS EQPAPMFALP EWTDESYRNV MWGSTTVEAK PPRVIENFLD VGHLAVVHEG YLGVSTHTII GDYHVIYDEH SIRSEEIEVF QPDPDGSGQA KNVYYTYEIL RPMTVKFTKR DKETDNKMSI VLTVAPKDAE TTIAYGILSF NYPMDLSDQE IAAFQDVIFA QDKPVVENQK PEDLPLDLQA ELSLACDRMS IAYRRYLKDS GLVWGTA HMM: 48-134 D LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL PADRAIPGKA RTFKYACKEE YGLVWVCLDS EQPAPMFALP EWTDES ALI: 6-88 VLR REWLVACRTD ELQEKPLGVM LMGERVVLFR NEEGIHAFKD LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL ENV: 2-126 IEDAVLR REWLVACRTD ELQEKPLGVM LMGERVVLFR NEEGIHAFKD LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL PADRAIPGKA RTFKYACKEE YGLVWVCLDS EQPAPMFA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
Sequence: MIIEDAVLR REWLVACRTD ELQEKPLGVM LMGERVVLFR NEEGIHAFKD LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL PADRAIPGKA RTFKYACKEE YGLVWVCLDS EQPAPMFALP EWTDESYRNV MWGSTTVEAK PPRVIENFLD VGHLAVVHEG YLGVSTHTII GDYHVIYDEH SIRSEEIEVF QPDPDGSGQA KNVYYTYEIL RPMTVKFTKR DKETDNKMSI VLTVAPKDAE TTIAYGILSF NYPMDLSDQE IAAFQDVIFA QDKPVVENQK PEDLPLDLQA ELSLACDRMS IAYRRYLKDS GLVWGTA HMM: 57-118 LS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL PADRAIPGKA RTFKYACKEE YGLVWVCLDS ALI: 30-88 MGERVVLFR NEEGIHAFKD LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL ENV: 5-130 AVLR REWLVACRTD ELQEKPLGVM LMGERVVLFR NEEGIHAFKD LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL PADRAIPGKA RTFKYACKEE YGLVWVCLDS EQPAPMFALP EW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
Sequence: MIIEDAVLR REWLVACRTD ELQEKPLGVM LMGERVVLFR NEEGIHAFKD LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL PADRAIPGKA RTFKYACKEE YGLVWVCLDS EQPAPMFALP EWTDESYRNV MWGSTTVEAK PPRVIENFLD VGHLAVVHEG YLGVSTHTII GDYHVIYDEH SIRSEEIEVF QPDPDGSGQA KNVYYTYEIL RPMTVKFTKR DKETDNKMSI VLTVAPKDAE TTIAYGILSF NYPMDLSDQE IAAFQDVIFA QDKPVVENQK PEDLPLDLQA ELSLACDRMS IAYRRYLKDS GLVWGTA HMM: 35-230 VLFR NEEGIHAFKD LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL PADRAIPGKA RTFKYACKEE YGLVWVCLDS EQPAPMFALP EWTDESYRNV MWGSTTVEAK PPRVIENFLD VGHLAVVHEG YLGVSTHTII GDYHVIYDEH SIRSEEIEVF QPDPDGSGQA KNVYYTYEIL RPMTVKFTKR DK ALI: 5-184 AVLR REWLVACRTD ELQEKPLGVM LMGERVVLFR NEEGIHAFKD LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL PADRAIPGKA RTFKYACKEE YGLVWVCLDS EQPAPMFALP EWTDESYRNV MWGSTTVEAK PPRVIENFLD VGHLAVVHEG YLGVSTHTII GDYHVI ENV: 3-290 EDAVLR REWLVACRTD ELQEKPLGVM LMGERVVLFR NEEGIHAFKD LCIHRGAKLS LGCVRDGNLV CPYHAWEYDG SGACVKIPQL PADRAIPGKA RTFKYACKEE YGLVWVCLDS EQPAPMFALP EWTDESYRNV MWGSTTVEAK PPRVIENFLD VGHLAVVHEG YLGVSTHTII GDYHVIYDEH SIRSEEIEVF QPDPDGSGQA KNVYYTYEIL RPMTVKFTKR DKETDNKMSI VLTVAPKDAE TTIAYGILSF NYPMDLSDQE IAAFQDVIFA QDKPVVENQK PE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
Sequence: MSNEVIELI TSHRSTRKYT DQPISEEILK ALFNAAQWAP SSHHVQAYSI IVVKNKETKQ SYLSSALSQA GPRNTLRLAQ CSSSFAQITI D
10 20 30 40 50 60 70 80 90
PF00881: 8-69 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
Sequence: MSNEVIELI TSHRSTRKYT DQPISEEILK ALFNAAQWAP SSHHVQAYSI IVVKNKETKQ SYLSSALSQA GPRNTLRLAQ CSSSFAQITI D HMM: 130-183 ALI: 19-72 DQPISEEILK ALFNAAQWAP SSHHVQAYSI IVVKNKETKQ SYLSSALSQA GPRN ENV: 11-88 HRSTRKYT DQPISEEILK ALFNAAQWAP SSHHVQAYSI IVVKNKETKQ SYLSSALSQA GPRNTLRLAQ CSSSFAQITI Position: 10 20 30 40 50 60 70 80 90
Sequence: MSNHNEHEK KGNARKEMTR RQFLAYTLGG TTAFMAGGVA LPMIRFAVNP LLEKKEKGSF IKVVEESKIT NEPQEFSFEK HQVDGWYESN AKLSAYISKG EDGKIFALSP ICQHLGCTIG WNNDKNFPNE YHCPCHGAHY TKDGKNLAVA PRPLKEYQMK IENGFIYLGD LIDNTRVK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170
PF00355: 61-156 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
Sequence: MSNHNEHEK KGNARKEMTR RQFLAYTLGG TTAFMAGGVA LPMIRFAVNP LLEKKEKGSF IKVVEESKIT NEPQEFSFEK HQVDGWYESN AKLSAYISKG EDGKIFALSP ICQHLGCTIG WNNDKNFPNE YHCPCHGAHY TKDGKNLAVA PRPLKEYQMK IENGFIYLGD LIDNTRVK HMM: 65-128 SKIT NEPQEFSFEK HQVDGWYESN AKLSAYISKG EDGKIFALSP ICQHLGCTIG WNNDKNFPNE ALI: 96-161 SKG EDGKIFALSP ICQHLGCTIG WNNDKNFPNE YHCPCHGAHY TKDGKNLAVA PRPLKEYQMK IEN ENV: 85-171 YESN AKLSAYISKG EDGKIFALSP ICQHLGCTIG WNNDKNFPNE YHCPCHGAHY TKDGKNLAVA PRPLKEYQMK IENGFIYLGD LID Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170
Sequence: MSNHNEHEK KGNARKEMTR RQFLAYTLGG TTAFMAGGVA LPMIRFAVNP LLEKKEKGSF IKVVEESKIT NEPQEFSFEK HQVDGWYESN AKLSAYISKG EDGKIFALSP ICQHLGCTIG WNNDKNFPNE YHCPCHGAHY TKDGKNLAVA PRPLKEYQMK IENGFIYLGD LIDNTRVK HMM: 69-121 NEPQEFSFEK HQVDGWYESN AKLSAYISKG EDGKIFALSP ICQHLGCTIG WNN ALI: 96-149 SKG EDGKIFALSP ICQHLGCTIG WNNDKNFPNE YHCPCHGAHY TKDGKNLAVA P ENV: 90-167 KLSAYISKG EDGKIFALSP ICQHLGCTIG WNNDKNFPNE YHCPCHGAHY TKDGKNLAVA PRPLKEYQMK IENGFIYLG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170
Sequence: MSVIEREVM DKQNGWRGFK DGKWSREVNV NNFIGLNITP YLGDEAFLAG PTENTTALWK IVSELTKKEI TNGGVLDVDV NHPSTIVSHG PGYLDKDKEQ IVGLQTDEPF KRSIQPFGGI KMMIDACKAY GFELPQEIIH MFTDIRKTHN QGVFDAYTSE MRAARKAGII TGLPDAYGRG RIIGDYRRVA LYGVDFLIKQ KQQDLKNLEL DSMTPEVIRD REEISEQIRA LGELKKMGEM HGFDISKPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK ASIETSSIQY ENDDLMRPYF GDDYGIACCV SAMRIGKQMQ FFGARANLAK ALLYAINGGV DEKSGAQVSP EFPRITSDVL DYNEVMKRYH NVMEWLAKLY VNTLNVIHFM HDKYSYERIE MALHDKDILR TMACGIAGLS VVADSLSAIK YAKVRPIRNE NGIAVDFEVE GEFPNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750
PF02901: 32-612 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF01228: 627-734 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MSVIEREVM DKQNGWRGFK DGKWSREVNV NNFIGLNITP YLGDEAFLAG PTENTTALWK IVSELTKKEI TNGGVLDVDV NHPSTIVSHG PGYLDKDKEQ IVGLQTDEPF KRSIQPFGGI KMMIDACKAY GFELPQEIIH MFTDIRKTHN QGVFDAYTSE MRAARKAGII TGLPDAYGRG RIIGDYRRVA LYGVDFLIKQ KQQDLKNLEL DSMTPEVIRD REEISEQIRA LGELKKMGEM HGFDISKPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK ASIETSSIQY ENDDLMRPYF GDDYGIACCV SAMRIGKQMQ FFGARANLAK ALLYAINGGV DEKSGAQVSP EFPRITSDVL DYNEVMKRYH NVMEWLAKLY VNTLNVIHFM HDKYSYERIE MALHDKDILR TMACGIAGLS VVADSLSAIK YAKVRPIRNE NGIAVDFEVE GEFPNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM HMM: 78-109 V NHPSTIVSHG PGYLDKDKEQ IVGLQTDEPF K ALI: 95-126 DKEQ IVGLQTDEPF KRSIQPFGGI KMMIDACK ENV: 85-146 VSHG PGYLDKDKEQ IVGLQTDEPF KRSIQPFGGI KMMIDACKAY GFELPQEIIH MFTDIRKT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750
Sequence: MSVIEREVM DKQNGWRGFK DGKWSREVNV NNFIGLNITP YLGDEAFLAG PTENTTALWK IVSELTKKEI TNGGVLDVDV NHPSTIVSHG PGYLDKDKEQ IVGLQTDEPF KRSIQPFGGI KMMIDACKAY GFELPQEIIH MFTDIRKTHN QGVFDAYTSE MRAARKAGII TGLPDAYGRG RIIGDYRRVA LYGVDFLIKQ KQQDLKNLEL DSMTPEVIRD REEISEQIRA LGELKKMGEM HGFDISKPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK ASIETSSIQY ENDDLMRPYF GDDYGIACCV SAMRIGKQMQ FFGARANLAK ALLYAINGGV DEKSGAQVSP EFPRITSDVL DYNEVMKRYH NVMEWLAKLY VNTLNVIHFM HDKYSYERIE MALHDKDILR TMACGIAGLS VVADSLSAIK YAKVRPIRNE NGIAVDFEVE GEFPNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM HMM: 634-817 MHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM ALI: 563-748 NYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF ENV: 553-751 VDFEVE GEFPNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750
Sequence: MSVIEREVM DKQNGWRGFK DGKWSREVNV NNFIGLNITP YLGDEAFLAG PTENTTALWK IVSELTKKEI TNGGVLDVDV NHPSTIVSHG PGYLDKDKEQ IVGLQTDEPF KRSIQPFGGI KMMIDACKAY GFELPQEIIH MFTDIRKTHN QGVFDAYTSE MRAARKAGII TGLPDAYGRG RIIGDYRRVA LYGVDFLIKQ KQQDLKNLEL DSMTPEVIRD REEISEQIRA LGELKKMGEM HGFDISKPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK ASIETSSIQY ENDDLMRPYF GDDYGIACCV SAMRIGKQMQ FFGARANLAK ALLYAINGGV DEKSGAQVSP EFPRITSDVL DYNEVMKRYH NVMEWLAKLY VNTLNVIHFM HDKYSYERIE MALHDKDILR TMACGIAGLS VVADSLSAIK YAKVRPIRNE NGIAVDFEVE GEFPNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM HMM: 276-421 GRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK ASIETSSIQY ENDDLMRPYF GDDYGIACCV SAM ALI: 232-378 LKKMGEM HGFDISKPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL ENV: 215-390 VIRD REEISEQIRA LGELKKMGEM HGFDISKPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK AS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750
Sequence: MSVIEREVM DKQNGWRGFK DGKWSREVNV NNFIGLNITP YLGDEAFLAG PTENTTALWK IVSELTKKEI TNGGVLDVDV NHPSTIVSHG PGYLDKDKEQ IVGLQTDEPF KRSIQPFGGI KMMIDACKAY GFELPQEIIH MFTDIRKTHN QGVFDAYTSE MRAARKAGII TGLPDAYGRG RIIGDYRRVA LYGVDFLIKQ KQQDLKNLEL DSMTPEVIRD REEISEQIRA LGELKKMGEM HGFDISKPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK ASIETSSIQY ENDDLMRPYF GDDYGIACCV SAMRIGKQMQ FFGARANLAK ALLYAINGGV DEKSGAQVSP EFPRITSDVL DYNEVMKRYH NVMEWLAKLY VNTLNVIHFM HDKYSYERIE MALHDKDILR TMACGIAGLS VVADSLSAIK YAKVRPIRNE NGIAVDFEVE GEFPNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM HMM: 482-561 EWLAKLY VNTLNVIHFM HDKYSYERIE MALHDKDILR TMACGIAGLS VVADSLSAIK YAKVRPIRNE NGIAVDFEVE GEF ALI: 424-504 GKQMQ FFGARANLAK ALLYAINGGV DEKSGAQVSP EFPRITSDVL DYNEVMKRYH NVMEWLAKLY VNTLNVIHFM HDKYSY ENV: 413-520 GIACCV SAMRIGKQMQ FFGARANLAK ALLYAINGGV DEKSGAQVSP EFPRITSDVL DYNEVMKRYH NVMEWLAKLY VNTLNVIHFM HDKYSYERIE MALHDKDILR TM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750
Sequence: MSVIEREVM DKQNGWRGFK DGKWSREVNV NNFIGLNITP YLGDEAFLAG PTENTTALWK IVSELTKKEI TNGGVLDVDV NHPSTIVSHG PGYLDKDKEQ IVGLQTDEPF KRSIQPFGGI KMMIDACKAY GFELPQEIIH MFTDIRKTHN QGVFDAYTSE MRAARKAGII TGLPDAYGRG RIIGDYRRVA LYGVDFLIKQ KQQDLKNLEL DSMTPEVIRD REEISEQIRA LGELKKMGEM HGFDISKPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK ASIETSSIQY ENDDLMRPYF GDDYGIACCV SAMRIGKQMQ FFGARANLAK ALLYAINGGV DEKSGAQVSP EFPRITSDVL DYNEVMKRYH NVMEWLAKLY VNTLNVIHFM HDKYSYERIE MALHDKDILR TMACGIAGLS VVADSLSAIK YAKVRPIRNE NGIAVDFEVE GEFPNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM HMM: 644-831 ASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM ALI: 562-750 PNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HG ENV: 550-752 GIAVDFEVE GEFPNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750
Sequence: MSVIEREVM DKQNGWRGFK DGKWSREVNV NNFIGLNITP YLGDEAFLAG PTENTTALWK IVSELTKKEI TNGGVLDVDV NHPSTIVSHG PGYLDKDKEQ IVGLQTDEPF KRSIQPFGGI KMMIDACKAY GFELPQEIIH MFTDIRKTHN QGVFDAYTSE MRAARKAGII TGLPDAYGRG RIIGDYRRVA LYGVDFLIKQ KQQDLKNLEL DSMTPEVIRD REEISEQIRA LGELKKMGEM HGFDISKPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK ASIETSSIQY ENDDLMRPYF GDDYGIACCV SAMRIGKQMQ FFGARANLAK ALLYAINGGV DEKSGAQVSP EFPRITSDVL DYNEVMKRYH NVMEWLAKLY VNTLNVIHFM HDKYSYERIE MALHDKDILR TMACGIAGLS VVADSLSAIK YAKVRPIRNE NGIAVDFEVE GEFPNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM HMM: 297-432 EE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK ASIETSSIQY ENDDLMRPYF GDDYGIACCV SAMRIGKQMQ FFGA ALI: 245-378 KPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL ENV: 221-403 EISEQIRA LGELKKMGEM HGFDISKPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK ASIETSSIQY ENDDL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750
Sequence: MSVIEREVM DKQNGWRGFK DGKWSREVNV NNFIGLNITP YLGDEAFLAG PTENTTALWK IVSELTKKEI TNGGVLDVDV NHPSTIVSHG PGYLDKDKEQ IVGLQTDEPF KRSIQPFGGI KMMIDACKAY GFELPQEIIH MFTDIRKTHN QGVFDAYTSE MRAARKAGII TGLPDAYGRG RIIGDYRRVA LYGVDFLIKQ KQQDLKNLEL DSMTPEVIRD REEISEQIRA LGELKKMGEM HGFDISKPAS NAKEAFQWLY FGYLAAIKEQ NGAAMSLGRT SSFLDIYVER DLQEGTLTEE QAQELVDHFV MKLRIVKFLR TPDYNELFSG DPTWVTESIG GMGVNGETRV TRNSFRFLHT LYNLGPAPEP NLTVLWSTKL PEGFKKYCAK ASIETSSIQY ENDDLMRPYF GDDYGIACCV SAMRIGKQMQ FFGARANLAK ALLYAINGGV DEKSGAQVSP EFPRITSDVL DYNEVMKRYH NVMEWLAKLY VNTLNVIHFM HDKYSYERIE MALHDKDILR TMACGIAGLS VVADSLSAIK YAKVRPIRNE NGIAVDFEVE GEFPNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM HMM: 662-846 SNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGSM ALI: 562-748 PNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF ENV: 548-751 E NGIAVDFEVE GEFPNYGNND DRVDAIAVEL VETFMGMIRK HQTYRNSLPT QSVLTITSNV VYGKKTGTTP DGRKAGEPFA PGANPMHGRD KKGALASLSS VAKLPYEHSL DGISNTFSIV PKALGKDEET RKTNLTSMMD GYFGSGAHHL NVNVFAREQL LDAMEHPENY PQLTIRVSGY AVNFIKLTKE QQMDVINRTF HGS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750
Sequence: MSTTMNMIK VIKLEDLAIQ IGKEVHVKEK SIAIFRLSNG DVRAVSNRCP HKNGPLAEGI VSGEFVFCPL HDWKISLVTG EVQKPDDGCI EVYPTEIRDG YVYLGGL
10 20 30 40 50 60 70 80 90 100
PF13806: 7-102 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
Sequence: MSTTMNMIK VIKLEDLAIQ IGKEVHVKEK SIAIFRLSNG DVRAVSNRCP HKNGPLAEGI VSGEFVFCPL HDWKISLVTG EVQKPDDGCI EVYPTEIRDG YVYLGGL HMM: 60-110 SGEFVFCPL HDWKISLVTG EVQKPDDGCI EVYPTEIRDG YVYLGGL ALI: 24-73 HVKEK SIAIFRLSNG DVRAVSNRCP HKNGPLAEGI VSGEFVFCPL HDWKI ENV: 22-83 EVHVKEK SIAIFRLSNG DVRAVSNRCP HKNGPLAEGI VSGEFVFCPL HDWKISLVTG EVQKP Position: 10 20 30 40 50 60 70 80 90 100
Sequence: MRYRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED TSFGDLIHQL TGGAIQNEIR GVKEVHAVDA AGVHPLLFAI GSERYTPYQQ VKQPAEILTQ ANRILGTGQL SLAKFLFMTA EEKGRNVSTH EMEDFLGYIL ERIDLHRDIH FQTNTTIDTL DYSGTGLNTG SKVIFAAVGD KKRELCTDVP ELMQGLPGFE QVNFVMPGIV AVRGPQFTSY PEAEQQVNDL CDAIRARGPL TTCPMIIFCD DPAYLSAELN NFLWVTFTRS NPSHDIYGVN SFYDFKHWGC DNVIIDARSK PHQAPPLIQD PEVEERIKRV FAKGASLSGV GMK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
PF01977: 11-434 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MRYRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED TSFGDLIHQL TGGAIQNEIR GVKEVHAVDA AGVHPLLFAI GSERYTPYQQ VKQPAEILTQ ANRILGTGQL SLAKFLFMTA EEKGRNVSTH EMEDFLGYIL ERIDLHRDIH FQTNTTIDTL DYSGTGLNTG SKVIFAAVGD KKRELCTDVP ELMQGLPGFE QVNFVMPGIV AVRGPQFTSY PEAEQQVNDL CDAIRARGPL TTCPMIIFCD DPAYLSAELN NFLWVTFTRS NPSHDIYGVN SFYDFKHWGC DNVIIDARSK PHQAPPLIQD PEVEERIKRV FAKGASLSGV GMK HMM: 2-306 YRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIY ALI: 3-318 RNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED ENV: 2-330 YRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED TSFGDLIHQL TG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MRYRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED TSFGDLIHQL TGGAIQNEIR GVKEVHAVDA AGVHPLLFAI GSERYTPYQQ VKQPAEILTQ ANRILGTGQL SLAKFLFMTA EEKGRNVSTH EMEDFLGYIL ERIDLHRDIH FQTNTTIDTL DYSGTGLNTG SKVIFAAVGD KKRELCTDVP ELMQGLPGFE QVNFVMPGIV AVRGPQFTSY PEAEQQVNDL CDAIRARGPL TTCPMIIFCD DPAYLSAELN NFLWVTFTRS NPSHDIYGVN SFYDFKHWGC DNVIIDARSK PHQAPPLIQD PEVEERIKRV FAKGASLSGV GMK HMM: 1-450 RYRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED TSFGDLIHQL TGGAIQNEIR GVKEVHAVDA AGVHPLLFAI GSERYTPYQQ VKQPAEILTQ ANRILGTGQL SLAKFLFMTA EEKGRNVSTH EMEDFLGYIL ERIDLHRDIH FQTNTTIDTL DYSGTGLNTG SK ALI: 1-462 RYRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED TSFGDLIHQL TGGAIQNEIR GVKEVHAVDA AGVHPLLFAI GSERYTPYQQ VKQPAEILTQ ANRILGTGQL SLAKFLFMTA EEKGRNVSTH EMEDFLGYIL ERIDLHRDIH FQTNTTIDTL DYSGTGLNTG SKVIFAAVGD KKRE ENV: 1-473 RYRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED TSFGDLIHQL TGGAIQNEIR GVKEVHAVDA AGVHPLLFAI GSERYTPYQQ VKQPAEILTQ ANRILGTGQL SLAKFLFMTA EEKGRNVSTH EMEDFLGYIL ERIDLHRDIH FQTNTTIDTL DYSGTGLNTG SKVIFAAVGD KKRELCTDVP ELMQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MRYRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED TSFGDLIHQL TGGAIQNEIR GVKEVHAVDA AGVHPLLFAI GSERYTPYQQ VKQPAEILTQ ANRILGTGQL SLAKFLFMTA EEKGRNVSTH EMEDFLGYIL ERIDLHRDIH FQTNTTIDTL DYSGTGLNTG SKVIFAAVGD KKRELCTDVP ELMQGLPGFE QVNFVMPGIV AVRGPQFTSY PEAEQQVNDL CDAIRARGPL TTCPMIIFCD DPAYLSAELN NFLWVTFTRS NPSHDIYGVN SFYDFKHWGC DNVIIDARSK PHQAPPLIQD PEVEERIKRV FAKGASLSGV GMK HMM: 378-416 Q ANRILGTGQL SLAKFLFMTA EEKGRNVSTH EMEDFLGY ALI: 516-555 GPL TTCPMIIFCD DPAYLSAELN NFLWVTFTRS NPSHDIY ENV: 505-559 VNDL CDAIRARGPL TTCPMIIFCD DPAYLSAELN NFLWVTFTRS NPSHDIYGVN S Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MRYRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED TSFGDLIHQL TGGAIQNEIR GVKEVHAVDA AGVHPLLFAI GSERYTPYQQ VKQPAEILTQ ANRILGTGQL SLAKFLFMTA EEKGRNVSTH EMEDFLGYIL ERIDLHRDIH FQTNTTIDTL DYSGTGLNTG SKVIFAAVGD KKRELCTDVP ELMQGLPGFE QVNFVMPGIV AVRGPQFTSY PEAEQQVNDL CDAIRARGPL TTCPMIIFCD DPAYLSAELN NFLWVTFTRS NPSHDIYGVN SFYDFKHWGC DNVIIDARSK PHQAPPLIQD PEVEERIKRV FAKGASLSGV GMK HMM: 1-317 RYRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQE ALI: 1-332 RYRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED TSFGDLIHQL TGGA ENV: 1-441 RYRNLEEC IIDLEKHGHL VRIREEVDPH LEMAAIHMKV YEAGGPALLF ENVKGSTYRA VSNLFGTMER SKFIFRDTWH STQNVIGLRN DPVKALKNPF KYIGTGVAAR KALPFKKSGG PAGFKEIQIS DMPLIKHWQG DGGAFVTLPQ VYSEDPEKPG IMNSNLGMYR VQLTGNDYKV NREVGIHYQI HRGIGVHQHK ANKRGEPLKV SVFIGGPPAH TLSAIMPLPE GMSELTFAGL LSGRHFRYTY VDGYCISLDA DFVITGEIHP EDTKPEGPFG DHLGYYSLIH PFPVMKVHKV YARENAIYPF TVVGRPPQED TSFGDLIHQL TGGAIQNEIR GVKEVHAVDA AGVHPLLFAI GSERYTPYQQ VKQPAEILTQ ANRILGTGQL SLAKFLFMTA EEKGRNVSTH EMEDFLGYIL ERIDLHRDIH FQTNTTIDTL DYS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MSQSNQQTY QNHKKVDPMY HFVLTLIVLI VLVASVVYVI REAFSYASVL LFGMAIVIVL LAALLRLYST KLQDRIIRQE ENFRYYRLTG KLLDPRLNVK QIIALRFAAD EEFPALCSKA AETGMQPDAI KQAITKWRAD HLRV
10 20 30 40 50 60 70 80 90 100 110 120 130 140
PF20136: 5-143 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
Sequence: MSQSNQQTY QNHKKVDPMY HFVLTLIVLI VLVASVVYVI REAFSYASVL LFGMAIVIVL LAALLRLYST KLQDRIIRQE ENFRYYRLTG KLLDPRLNVK QIIALRFAAD EEFPALCSKA AETGMQPDAI KQAITKWRAD HLRV HMM: 7-115 TY QNHKKVDPMY HFVLTLIVLI VLVASVVYVI REAFSYASVL LFGMAIVIVL LAALLRLYST KLQDRIIRQE ENFRYYRLTG KLLDPRLNVK QIIALRFAAD EEFPALC ALI: 4-111 NQQTY QNHKKVDPMY HFVLTLIVLI VLVASVVYVI REAFSYASVL LFGMAIVIVL LAALLRLYST KLQDRIIRQE ENFRYYRLTG KLLDPRLNVK QIIALRFAAD EEF ENV: 1-125 SQSNQQTY QNHKKVDPMY HFVLTLIVLI VLVASVVYVI REAFSYASVL LFGMAIVIVL LAALLRLYST KLQDRIIRQE ENFRYYRLTG KLLDPRLNVK QIIALRFAAD EEFPALCSKA AETGMQP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140
Sequence: MEVLSTIVN VVVLLALIGI LLYMQKKHVS FSKRVFTALG LGILFGVSLQ LIFGRSSDVI KDSVDWFSLV GNGYVKLLQM VAIPLIMVSI ISAIIKVKAK SGVGKLSTLI IGLLLFTTAI SAAVGISAAL GFNLKTVNIE QGEKEQKRGE YLNGKLADVE DKTIPQQVLD VIPSNPFDDM TGSRPTSTIA VVIFAAFIGI AVRGIAKKKP AEAELFTKFV EAVYAVVMRI VTLVLRLTPY GILALIAKVT ATTNYAEIAK LGQFVIASYV ALIVMFIIHL IIIAVNGLNP VTYVRKALPV LSFAFTSRTS AGALPLNVDT QVKKLGVSEG IANFSASFGL SIGQNGCAGI YPAMLAIMIA PTVGIDPFSF SFIATLIAVV TISSFGVAGV GGGATFAAII VLSTMNLPVA LAGLLISVEP LIDMGRTALN VSGSMTAGLV TSKVTKDLDV NVYNTPSRAE DVDGGVPA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460
PF00375: 31-442 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
Sequence: MEVLSTIVN VVVLLALIGI LLYMQKKHVS FSKRVFTALG LGILFGVSLQ LIFGRSSDVI KDSVDWFSLV GNGYVKLLQM VAIPLIMVSI ISAIIKVKAK SGVGKLSTLI IGLLLFTTAI SAAVGISAAL GFNLKTVNIE QGEKEQKRGE YLNGKLADVE DKTIPQQVLD VIPSNPFDDM TGSRPTSTIA VVIFAAFIGI AVRGIAKKKP AEAELFTKFV EAVYAVVMRI VTLVLRLTPY GILALIAKVT ATTNYAEIAK LGQFVIASYV ALIVMFIIHL IIIAVNGLNP VTYVRKALPV LSFAFTSRTS AGALPLNVDT QVKKLGVSEG IANFSASFGL SIGQNGCAGI YPAMLAIMIA PTVGIDPFSF SFIATLIAVV TISSFGVAGV GGGATFAAII VLSTMNLPVA LAGLLISVEP LIDMGRTALN VSGSMTAGLV TSKVTKDLDV NVYNTPSRAE DVDGGVPA HMM: 26-140 HVS FSKRVFTALG LGILFGVSLQ LIFGRSSDVI KDSVDWFSLV GNGYVKLLQM VAIPLIMVSI ISAIIKVKAK SGVGKLSTLI IGLLLFTTAI SAAVGISAAL GFNLKTVNIE QG ALI: 11-129 VLLALIGI LLYMQKKHVS FSKRVFTALG LGILFGVSLQ LIFGRSSDVI KDSVDWFSLV GNGYVKLLQM VAIPLIMVSI ISAIIKVKAK SGVGKLSTLI IGLLLFTTAI SAAVGISAAL G ENV: 3-141 LSTIVN VVVLLALIGI LLYMQKKHVS FSKRVFTALG LGILFGVSLQ LIFGRSSDVI KDSVDWFSLV GNGYVKLLQM VAIPLIMVSI ISAIIKVKAK SGVGKLSTLI IGLLLFTTAI SAAVGISAAL GFNLKTVNIE QGE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460
Sequence: MSTENVDKK LLDPEFEHAP VPQEYRKKLS SVAAVWFGFP MVLTSAVIGG LITAQLGFKA GALAMLLGNL LLFVMVGLLS YDAGRSGMNF SLTAQKTFGR SGYYIISGLL STVVIGWFAL QVGLTGSTMH GSFGASLLLM TIIGGVLYVA ITYVGIKALS ILGWIAAPFY IIIAIIVIAM AVKNGRSDIL NYHPQVTGAM SFGAAVTLVF AGFADSGTMT ADFTRWAKNG REGALSVIFA FPIGNFIAEL VGGIVVATGV IPNATSTGGD FMSVLAGHGP LLTILSILFV FINLGSVGTH CLYNGAVGWS HMTGKKMRTI TLIIGVVGLI AAISGIYNHF FDWLVLLGVI IPPIGSIIIM DRLVLRKNNS ADLVSWRPLA FIVWILSAAI SLVVNFYAPE LSVAVVGLVT SAIFYAIGSM MVKGNARTVK NTM
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430
PF02133: 18-405 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
Sequence: MSTENVDKK LLDPEFEHAP VPQEYRKKLS SVAAVWFGFP MVLTSAVIGG LITAQLGFKA GALAMLLGNL LLFVMVGLLS YDAGRSGMNF SLTAQKTFGR SGYYIISGLL STVVIGWFAL QVGLTGSTMH GSFGASLLLM TIIGGVLYVA ITYVGIKALS ILGWIAAPFY IIIAIIVIAM AVKNGRSDIL NYHPQVTGAM SFGAAVTLVF AGFADSGTMT ADFTRWAKNG REGALSVIFA FPIGNFIAEL VGGIVVATGV IPNATSTGGD FMSVLAGHGP LLTILSILFV FINLGSVGTH CLYNGAVGWS HMTGKKMRTI TLIIGVVGLI AAISGIYNHF FDWLVLLGVI IPPIGSIIIM DRLVLRKNNS ADLVSWRPLA FIVWILSAAI SLVVNFYAPE LSVAVVGLVT SAIFYAIGSM MVKGNARTVK NTM HMM: 19-137 VPQEYRKKLS SVAAVWFGFP MVLTSAVIGG LITAQLGFKA GALAMLLGNL LLFVMVGLLS YDAGRSGMNF SLTAQKTFGR SGYYIISGLL STVVIGWFAL QVGLTGSTMH GSFGASLLL ALI: 34-151 WFGFP MVLTSAVIGG LITAQLGFKA GALAMLLGNL LLFVMVGLLS YDAGRSGMNF SLTAQKTFGR SGYYIISGLL STVVIGWFAL QVGLTGSTMH GSFGASLLLM TIIGGVLYVA ITY ENV: 17-157 AP VPQEYRKKLS SVAAVWFGFP MVLTSAVIGG LITAQLGFKA GALAMLLGNL LLFVMVGLLS YDAGRSGMNF SLTAQKTFGR SGYYIISGLL STVVIGWFAL QVGLTGSTMH GSFGASLLLM TIIGGVLYVA ITYVGIKAL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430
Sequence: MSTENVDKK LLDPEFEHAP VPQEYRKKLS SVAAVWFGFP MVLTSAVIGG LITAQLGFKA GALAMLLGNL LLFVMVGLLS YDAGRSGMNF SLTAQKTFGR SGYYIISGLL STVVIGWFAL QVGLTGSTMH GSFGASLLLM TIIGGVLYVA ITYVGIKALS ILGWIAAPFY IIIAIIVIAM AVKNGRSDIL NYHPQVTGAM SFGAAVTLVF AGFADSGTMT ADFTRWAKNG REGALSVIFA FPIGNFIAEL VGGIVVATGV IPNATSTGGD FMSVLAGHGP LLTILSILFV FINLGSVGTH CLYNGAVGWS HMTGKKMRTI TLIIGVVGLI AAISGIYNHF FDWLVLLGVI IPPIGSIIIM DRLVLRKNNS ADLVSWRPLA FIVWILSAAI SLVVNFYAPE LSVAVVGLVT SAIFYAIGSM MVKGNARTVK NTM HMM: 244-263 FIAEL VGGIVVATGV IPNAT ALI: 157-176 LS ILGWIAAPFY IIIAIIVI ENV: 129-181 GSFGASLLLM TIIGGVLYVA ITYVGIKALS ILGWIAAPFY IIIAIIVIAM AVK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430
Sequence: MDDKKFTLW VLAWPIFIEV FLQFLLGTAD TLMVSRISDD AVAVVGFSNQ LFNALMILFT TVASGAGILI AQKMGSRQQE HARTIGMMAL NVGTAIGLLL SLLLILFPVP IARMLQMPEP LLPLGKIYIA IVGGGMVLTA IMSTLSTVIR STGNTKGPMF IAIGMNVVHI FFNYAFIFGA FGFPQWGLTG VAISTLLSRV LGTIMLMGMF LNTFERRVTW RDLWTFDAKL FKDVMRIAWP LGVNMASWVF SQLIIFTFIS MLGSKEMAAR TYMNTLESFC FLLGSSVAMA VQIQVAHLFG GKRTDLAYRS AYRALGIGLV LVTVNAFIIY LFGRQFLGFF TTNPEIIALG ASLLGLNLIL QPGKMMNMAL GNSLNAVGDS RYTMTIAILS MWSIATGLSY ALGIHLGWGL IGIYCCMIAD EYLRGILVWF RWKGQKKLRY AERLEPVSIK TCIQSEVL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450
PF01554: 238-399 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
Sequence: MDDKKFTLW VLAWPIFIEV FLQFLLGTAD TLMVSRISDD AVAVVGFSNQ LFNALMILFT TVASGAGILI AQKMGSRQQE HARTIGMMAL NVGTAIGLLL SLLLILFPVP IARMLQMPEP LLPLGKIYIA IVGGGMVLTA IMSTLSTVIR STGNTKGPMF IAIGMNVVHI FFNYAFIFGA FGFPQWGLTG VAISTLLSRV LGTIMLMGMF LNTFERRVTW RDLWTFDAKL FKDVMRIAWP LGVNMASWVF SQLIIFTFIS MLGSKEMAAR TYMNTLESFC FLLGSSVAMA VQIQVAHLFG GKRTDLAYRS AYRALGIGLV LVTVNAFIIY LFGRQFLGFF TTNPEIIALG ASLLGLNLIL QPGKMMNMAL GNSLNAVGDS RYTMTIAILS MWSIATGLSY ALGIHLGWGL IGIYCCMIAD EYLRGILVWF RWKGQKKLRY AERLEPVSIK TCIQSEVL HMM: 122-159 LGKIYIA IVGGGMVLTA IMSTLSTVIR STGNTKGPMF I ALI: 53-90 LMILFT TVASGAGILI AQKMGSRQQE HARTIGMMAL NV ENV: 10-93 LAWPIFIEV FLQFLLGTAD TLMVSRISDD AVAVVGFSNQ LFNALMILFT TVASGAGILI AQKMGSRQQE HARTIGMMAL NVGTA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450
Sequence: MDDKKFTLW VLAWPIFIEV FLQFLLGTAD TLMVSRISDD AVAVVGFSNQ LFNALMILFT TVASGAGILI AQKMGSRQQE HARTIGMMAL NVGTAIGLLL SLLLILFPVP IARMLQMPEP LLPLGKIYIA IVGGGMVLTA IMSTLSTVIR STGNTKGPMF IAIGMNVVHI FFNYAFIFGA FGFPQWGLTG VAISTLLSRV LGTIMLMGMF LNTFERRVTW RDLWTFDAKL FKDVMRIAWP LGVNMASWVF SQLIIFTFIS MLGSKEMAAR TYMNTLESFC FLLGSSVAMA VQIQVAHLFG GKRTDLAYRS AYRALGIGLV LVTVNAFIIY LFGRQFLGFF TTNPEIIALG ASLLGLNLIL QPGKMMNMAL GNSLNAVGDS RYTMTIAILS MWSIATGLSY ALGIHLGWGL IGIYCCMIAD EYLRGILVWF RWKGQKKLRY AERLEPVSIK TCIQSEVL HMM: 91-151 GTAIGLLL SLLLILFPVP IARMLQMPEP LLPLGKIYIA IVGGGMVLTA IMSTLSTVIR STG ALI: 247-307 VF SQLIIFTFIS MLGSKEMAAR TYMNTLESFC FLLGSSVAMA VQIQVAHLFG GKRTDLAYR ENV: 243-337 MASWVF SQLIIFTFIS MLGSKEMAAR TYMNTLESFC FLLGSSVAMA VQIQVAHLFG GKRTDLAYRS AYRALGIGLV LVTVNAFIIY LFGRQFLGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450
Sequence: MDDKKFTLW VLAWPIFIEV FLQFLLGTAD TLMVSRISDD AVAVVGFSNQ LFNALMILFT TVASGAGILI AQKMGSRQQE HARTIGMMAL NVGTAIGLLL SLLLILFPVP IARMLQMPEP LLPLGKIYIA IVGGGMVLTA IMSTLSTVIR STGNTKGPMF IAIGMNVVHI FFNYAFIFGA FGFPQWGLTG VAISTLLSRV LGTIMLMGMF LNTFERRVTW RDLWTFDAKL FKDVMRIAWP LGVNMASWVF SQLIIFTFIS MLGSKEMAAR TYMNTLESFC FLLGSSVAMA VQIQVAHLFG GKRTDLAYRS AYRALGIGLV LVTVNAFIIY LFGRQFLGFF TTNPEIIALG ASLLGLNLIL QPGKMMNMAL GNSLNAVGDS RYTMTIAILS MWSIATGLSY ALGIHLGWGL IGIYCCMIAD EYLRGILVWF RWKGQKKLRY AERLEPVSIK TCIQSEVL HMM: 218-253 W RDLWTFDAKL FKDVMRIAWP LGVNMASWVF SQLII ALI: 375-410 VGDS RYTMTIAILS MWSIATGLSY ALGIHLGWGL IG ENV: 371-416 SLNAVGDS RYTMTIAILS MWSIATGLSY ALGIHLGWGL IGIYCCMI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450
Sequence: MMEEIDILV IGGGQAGLAA GYYLKHTAKS FLIISKERRI GNVWRHRYDS LVLFTPRWFS ALPGRRLEGD PNGFATKNEI ADYMERYAES MSLPVQLNTE ILGISKMGES FHIRTAAVEY IAKQVIIATG PFQKPFLPEI ACQVPQSIFQ THTAAYTNPS ILQEGPVLVV GAGNSGAQIA VELSKDRQVY LSANHALKFF PLQFLGQSIF WWFDRLGLLH SARDSKIGAF IRRQGDPIFG MELKRGIREG RIHLQPRTTG FHQDAVTFID GSQVIVRNII WATGFRSDYS YMHLPGALND EGMPRHRRGV SPVTGLFYVG LPWQHERGSA LIGGVGEDAK YIVKVMNAL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
PF13738: 7-190 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
Sequence: MMEEIDILV IGGGQAGLAA GYYLKHTAKS FLIISKERRI GNVWRHRYDS LVLFTPRWFS ALPGRRLEGD PNGFATKNEI ADYMERYAES MSLPVQLNTE ILGISKMGES FHIRTAAVEY IAKQVIIATG PFQKPFLPEI ACQVPQSIFQ THTAAYTNPS ILQEGPVLVV GAGNSGAQIA VELSKDRQVY LSANHALKFF PLQFLGQSIF WWFDRLGLLH SARDSKIGAF IRRQGDPIFG MELKRGIREG RIHLQPRTTG FHQDAVTFID GSQVIVRNII WATGFRSDYS YMHLPGALND EGMPRHRRGV SPVTGLFYVG LPWQHERGSA LIGGVGEDAK YIVKVMNAL HMM: 5-47 DILV IGGGQAGLAA GYYLKHTAKS FLIISKERRI GNVWRHRYD ALI: 4-44 IDILV IGGGQAGLAA GYYLKHTAKS FLIISKERRI GNVWRH ENV: 1-53 MEEIDILV IGGGQAGLAA GYYLKHTAKS FLIISKERRI GNVWRHRYDS LVLFT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
Sequence: MMEEIDILV IGGGQAGLAA GYYLKHTAKS FLIISKERRI GNVWRHRYDS LVLFTPRWFS ALPGRRLEGD PNGFATKNEI ADYMERYAES MSLPVQLNTE ILGISKMGES FHIRTAAVEY IAKQVIIATG PFQKPFLPEI ACQVPQSIFQ THTAAYTNPS ILQEGPVLVV GAGNSGAQIA VELSKDRQVY LSANHALKFF PLQFLGQSIF WWFDRLGLLH SARDSKIGAF IRRQGDPIFG MELKRGIREG RIHLQPRTTG FHQDAVTFID GSQVIVRNII WATGFRSDYS YMHLPGALND EGMPRHRRGV SPVTGLFYVG LPWQHERGSA LIGGVGEDAK YIVKVMNAL HMM: 8-27 V IGGGQAGLAA GYYLKHTAK ALI: 166-185 LVV GAGNSGAQIA VELSKDR ENV: 162-190 EGPVLVV GAGNSGAQIA VELSKDRQVY LS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
Sequence: MMEEIDILV IGGGQAGLAA GYYLKHTAKS FLIISKERRI GNVWRHRYDS LVLFTPRWFS ALPGRRLEGD PNGFATKNEI ADYMERYAES MSLPVQLNTE ILGISKMGES FHIRTAAVEY IAKQVIIATG PFQKPFLPEI ACQVPQSIFQ THTAAYTNPS ILQEGPVLVV GAGNSGAQIA VELSKDRQVY LSANHALKFF PLQFLGQSIF WWFDRLGLLH SARDSKIGAF IRRQGDPIFG MELKRGIREG RIHLQPRTTG FHQDAVTFID GSQVIVRNII WATGFRSDYS YMHLPGALND EGMPRHRRGV SPVTGLFYVG LPWQHERGSA LIGGVGEDAK YIVKVMNAL HMM: 1-46 MEEIDILV IGGGQAGLAA GYYLKHTAKS FLIISKERRI GNVWRHRY ALI: 1-44 MEEIDILV IGGGQAGLAA GYYLKHTAKS FLIISKERRI GNVWRH ENV: 1-51 MEEIDILV IGGGQAGLAA GYYLKHTAKS FLIISKERRI GNVWRHRYDS LVL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
Sequence: MMEEIDILV IGGGQAGLAA GYYLKHTAKS FLIISKERRI GNVWRHRYDS LVLFTPRWFS ALPGRRLEGD PNGFATKNEI ADYMERYAES MSLPVQLNTE ILGISKMGES FHIRTAAVEY IAKQVIIATG PFQKPFLPEI ACQVPQSIFQ THTAAYTNPS ILQEGPVLVV GAGNSGAQIA VELSKDRQVY LSANHALKFF PLQFLGQSIF WWFDRLGLLH SARDSKIGAF IRRQGDPIFG MELKRGIREG RIHLQPRTTG FHQDAVTFID GSQVIVRNII WATGFRSDYS YMHLPGALND EGMPRHRRGV SPVTGLFYVG LPWQHERGSA LIGGVGEDAK YIVKVMNAL HMM: 7-26 LV IGGGQAGLAA GYYLKHTA ALI: 166-185 LVV GAGNSGAQIA VELSKDR ENV: 162-190 EGPVLVV GAGNSGAQIA VELSKDRQVY LS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
Sequence: MKKLVILGG GYGGLAVANR LLEGEIPVDT SVMLIDRQPY QGLKTEYYAL AAGTASDLQI RVAFPTDPRI ELKYGDITRI DLQAKHVYLN AEEVIPYDQL VIALGCTDKF HGILGAEQYA ESIQSLSRTR RTYQALNDVK PYGQVNIMGG GLSGVEVAAE LRESRPDLNI RIIDRGPRVL SAFPEKLSAF VSEWFHEHHV DLSSHISTTQ LEQGGIIHQN GVIYSDVTVW TAGIQPVKPV QDLDVPKDPQ GRVLLNLHYQ IPGHEDVFVV GDCASLSFSP SAQAAGAQGE QVADVIQASW KGEEPKLGKI KLKGVLGSLG KKSGFGLLGN RTMMGRVPRV LKMGVLWRSK HHFG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF07992: 2-288 ◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MKKLVILGG GYGGLAVANR LLEGEIPVDT SVMLIDRQPY QGLKTEYYAL AAGTASDLQI RVAFPTDPRI ELKYGDITRI DLQAKHVYLN AEEVIPYDQL VIALGCTDKF HGILGAEQYA ESIQSLSRTR RTYQALNDVK PYGQVNIMGG GLSGVEVAAE LRESRPDLNI RIIDRGPRVL SAFPEKLSAF VSEWFHEHHV DLSSHISTTQ LEQGGIIHQN GVIYSDVTVW TAGIQPVKPV QDLDVPKDPQ GRVLLNLHYQ IPGHEDVFVV GDCASLSFSP SAQAAGAQGE QVADVIQASW KGEEPKLGKI KLKGVLGSLG KKSGFGLLGN RTMMGRVPRV LKMGVLWRSK HHFG HMM: 5-42 ILGG GYGGLAVANR LLEGEIPVDT SVMLIDRQPY QGLK ALI: 141-178 GQVNIMGG GLSGVEVAAE LRESRPDLNI RIIDRGPRVL ENV: 138-183 K PYGQVNIMGG GLSGVEVAAE LRESRPDLNI RIIDRGPRVL SAFPE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MRSTYTHLS DISTPAAMNP YVSVIRNGLS KTKHPKHIMI VGAGMAGLVA ASLLKDAGHH VNIIEGSNRV GGRVLTFRFS EETYFEAGAM RIPEMHDLVF EYIRKFGLLV NPFINSTPED FIYANGILTR AKIYERDPDI LRYPVAPSER GKTAQQLFNM AVQPIIDFIN KDPERNWPIV EKQLDQYSVY TFLKFYPYRP KTTFSEGAIE MMSVLLSLEG IMEEAFLEIL RDMMLFKPET RFYEITGGND RLPQAFLPQL QQNIIFNQRV TKIIQHSDCV TLNYMDTQSF DPYAMSGDLA IMTIPFTVMQ QVEVEPRNSF SHNKWRAIRE LHYMRATKIG FAFRNRFWEQ QGLYGGKTMT DLPVRSAYYP SHVFDNARPA ALLASYTWED DTMPWDGLSQ DQRIYFALRN LATIHGDQVY REFITGASYS WTLDPFACGA VTFFKPGQQS ALFPYIPTPE GRVHFAGEHT TLTHGWIQGA IESGIRVALE VNDLPKA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490
PF01593: 43-490 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MRSTYTHLS DISTPAAMNP YVSVIRNGLS KTKHPKHIMI VGAGMAGLVA ASLLKDAGHH VNIIEGSNRV GGRVLTFRFS EETYFEAGAM RIPEMHDLVF EYIRKFGLLV NPFINSTPED FIYANGILTR AKIYERDPDI LRYPVAPSER GKTAQQLFNM AVQPIIDFIN KDPERNWPIV EKQLDQYSVY TFLKFYPYRP KTTFSEGAIE MMSVLLSLEG IMEEAFLEIL RDMMLFKPET RFYEITGGND RLPQAFLPQL QQNIIFNQRV TKIIQHSDCV TLNYMDTQSF DPYAMSGDLA IMTIPFTVMQ QVEVEPRNSF SHNKWRAIRE LHYMRATKIG FAFRNRFWEQ QGLYGGKTMT DLPVRSAYYP SHVFDNARPA ALLASYTWED DTMPWDGLSQ DQRIYFALRN LATIHGDQVY REFITGASYS WTLDPFACGA VTFFKPGQQS ALFPYIPTPE GRVHFAGEHT TLTHGWIQGA IESGIRVALE VNDLPKA HMM: 7-51 LS DISTPAAMNP YVSVIRNGLS KTKHPKHIMI VGAGMAGLVA ASL ALI: 36-78 IMI VGAGMAGLVA ASLLKDAGHH VNIIEGSNRV GGRVLTFRFS ENV: 30-81 TKHPKHIMI VGAGMAGLVA ASLLKDAGHH VNIIEGSNRV GGRVLTFRFS EET Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490
Sequence: MRSTYTHLS DISTPAAMNP YVSVIRNGLS KTKHPKHIMI VGAGMAGLVA ASLLKDAGHH VNIIEGSNRV GGRVLTFRFS EETYFEAGAM RIPEMHDLVF EYIRKFGLLV NPFINSTPED FIYANGILTR AKIYERDPDI LRYPVAPSER GKTAQQLFNM AVQPIIDFIN KDPERNWPIV EKQLDQYSVY TFLKFYPYRP KTTFSEGAIE MMSVLLSLEG IMEEAFLEIL RDMMLFKPET RFYEITGGND RLPQAFLPQL QQNIIFNQRV TKIIQHSDCV TLNYMDTQSF DPYAMSGDLA IMTIPFTVMQ QVEVEPRNSF SHNKWRAIRE LHYMRATKIG FAFRNRFWEQ QGLYGGKTMT DLPVRSAYYP SHVFDNARPA ALLASYTWED DTMPWDGLSQ DQRIYFALRN LATIHGDQVY REFITGASYS WTLDPFACGA VTFFKPGQQS ALFPYIPTPE GRVHFAGEHT TLTHGWIQGA IESGIRVALE VNDLPKA HMM: 6-50 HLS DISTPAAMNP YVSVIRNGLS KTKHPKHIMI VGAGMAGLVA AS ALI: 36-78 IMI VGAGMAGLVA ASLLKDAGHH VNIIEGSNRV GGRVLTFRFS ENV: 32-82 HPKHIMI VGAGMAGLVA ASLLKDAGHH VNIIEGSNRV GGRVLTFRFS EETY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490
Sequence: MRSTYTHLS DISTPAAMNP YVSVIRNGLS KTKHPKHIMI VGAGMAGLVA ASLLKDAGHH VNIIEGSNRV GGRVLTFRFS EETYFEAGAM RIPEMHDLVF EYIRKFGLLV NPFINSTPED FIYANGILTR AKIYERDPDI LRYPVAPSER GKTAQQLFNM AVQPIIDFIN KDPERNWPIV EKQLDQYSVY TFLKFYPYRP KTTFSEGAIE MMSVLLSLEG IMEEAFLEIL RDMMLFKPET RFYEITGGND RLPQAFLPQL QQNIIFNQRV TKIIQHSDCV TLNYMDTQSF DPYAMSGDLA IMTIPFTVMQ QVEVEPRNSF SHNKWRAIRE LHYMRATKIG FAFRNRFWEQ QGLYGGKTMT DLPVRSAYYP SHVFDNARPA ALLASYTWED DTMPWDGLSQ DQRIYFALRN LATIHGDQVY REFITGASYS WTLDPFACGA VTFFKPGQQS ALFPYIPTPE GRVHFAGEHT TLTHGWIQGA IESGIRVALE VNDLPKA HMM: 399-433 DQRIYFALRN LATIHGDQVY REFITGASYS WTLDP ALI: 274-309 HSDCV TLNYMDTQSF DPYAMSGDLA IMTIPFTVMQ Q ENV: 264-314 FNQRV TKIIQHSDCV TLNYMDTQSF DPYAMSGDLA IMTIPFTVMQ QVEVEP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490
Sequence: MTGELELYD VTIIGGGPAG MYAAFYSGMR DMKTKIIEAR EELGGRMLIY PEKMIWDVGG FAPIQCEQLI VELARQARLF DPTLVFGQQV RGLERMADGT YVLVTASGER HWTRTIILAL GRGILQMEKL EIEGADRYEV TNLHYTVQAL EPFRGKRVLI SGGGNSAIDW ANELEPIAER VVVVHRRDQF GGHEKNVLRM KASSVEVRTP YVVQQLHSRD EQQIDQVTIR HLESGETERM DVDAVIVNHG LKSDFTGITA WGLRMDDWNV FVSEKLATNL PGVFAAGDFV YYESKVNLIA GAFSDAVLAV NSAILYLDPE APRVAYVSSH NDRFKEKNRA YGVRDE
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
PF07992: 7-297 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MTGELELYD VTIIGGGPAG MYAAFYSGMR DMKTKIIEAR EELGGRMLIY PEKMIWDVGG FAPIQCEQLI VELARQARLF DPTLVFGQQV RGLERMADGT YVLVTASGER HWTRTIILAL GRGILQMEKL EIEGADRYEV TNLHYTVQAL EPFRGKRVLI SGGGNSAIDW ANELEPIAER VVVVHRRDQF GGHEKNVLRM KASSVEVRTP YVVQQLHSRD EQQIDQVTIR HLESGETERM DVDAVIVNHG LKSDFTGITA WGLRMDDWNV FVSEKLATNL PGVFAAGDFV YYESKVNLIA GAFSDAVLAV NSAILYLDPE APRVAYVSSH NDRFKEKNRA YGVRDE HMM: 5-46 ELYD VTIIGGGPAG MYAAFYSGMR DMKTKIIEAR EELGGRML ALI: 7-46 YD VTIIGGGPAG MYAAFYSGMR DMKTKIIEAR EELGGRML ENV: 4-54 LELYD VTIIGGGPAG MYAAFYSGMR DMKTKIIEAR EELGGRMLIY PEKMIW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
Sequence: MTGELELYD VTIIGGGPAG MYAAFYSGMR DMKTKIIEAR EELGGRMLIY PEKMIWDVGG FAPIQCEQLI VELARQARLF DPTLVFGQQV RGLERMADGT YVLVTASGER HWTRTIILAL GRGILQMEKL EIEGADRYEV TNLHYTVQAL EPFRGKRVLI SGGGNSAIDW ANELEPIAER VVVVHRRDQF GGHEKNVLRM KASSVEVRTP YVVQQLHSRD EQQIDQVTIR HLESGETERM DVDAVIVNHG LKSDFTGITA WGLRMDDWNV FVSEKLATNL PGVFAAGDFV YYESKVNLIA GAFSDAVLAV NSAILYLDPE APRVAYVSSH NDRFKEKNRA YGVRDE HMM: 176-210 AER VVVVHRRDQF GGHEKNVLRM KASSVEVRTP YV ALI: 152-186 RGKRVLI SGGGNSAIDW ANELEPIAER VVVVHRRD ENV: 109-197 HWTRTIILAL GRGILQMEKL EIEGADRYEV TNLHYTVQAL EPFRGKRVLI SGGGNSAIDW ANELEPIAER VVVVHRRDQF GGHEKNVLR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
Sequence: MTGELELYD VTIIGGGPAG MYAAFYSGMR DMKTKIIEAR EELGGRMLIY PEKMIWDVGG FAPIQCEQLI VELARQARLF DPTLVFGQQV RGLERMADGT YVLVTASGER HWTRTIILAL GRGILQMEKL EIEGADRYEV TNLHYTVQAL EPFRGKRVLI SGGGNSAIDW ANELEPIAER VVVVHRRDQF GGHEKNVLRM KASSVEVRTP YVVQQLHSRD EQQIDQVTIR HLESGETERM DVDAVIVNHG LKSDFTGITA WGLRMDDWNV FVSEKLATNL PGVFAAGDFV YYESKVNLIA GAFSDAVLAV NSAILYLDPE APRVAYVSSH NDRFKEKNRA YGVRDE HMM: 316-366 DPE APRVAYVSSH NDRFKEKNRA YGVRDE ALI: 221-273 QIDQVTIR HLESGETERM DVDAVIVNHG LKSDFTGITA WGLRMDDWNV FVSEK ENV: 210-278 VVQQLHSRD EQQIDQVTIR HLESGETERM DVDAVIVNHG LKSDFTGITA WGLRMDDWNV FVSEKLATNL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
Sequence: MEQTVDVII VGGGVIGCSI AYHLSKRGIK VRLLERGRIA SEASSAAAGM LAAQAEFIDS VPLFDWARQS RAMFPALTAD LQAHSGMEIG LVQQGLLRVA TSEEDVLRYH AQAELQRQSG ESAQWLSAQE ALALEGTLAS DVYGALYLEN DHQVVAPSLT LAYASAAAAL GAEIREHSEV QELLREGGRI TGVRMQDGIH RCQQVIIASS IWSQALLRTV GYDLPLYPVK GECIAVRTNK PLIRRTIYTD NCYLVPKANG ELLIGATVTP HTMQRHVTVG GILALMGVAE RLIPSIRGAT WIRTWSGLRP QTPQGLPYIG NHPELAGLMI AAGHYRNGIL LSPLTGSVMA DLVEGIELAA DLTAFQVPAM RWSKDQEMTG VGI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF01266: 5-351 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MEQTVDVII VGGGVIGCSI AYHLSKRGIK VRLLERGRIA SEASSAAAGM LAAQAEFIDS VPLFDWARQS RAMFPALTAD LQAHSGMEIG LVQQGLLRVA TSEEDVLRYH AQAELQRQSG ESAQWLSAQE ALALEGTLAS DVYGALYLEN DHQVVAPSLT LAYASAAAAL GAEIREHSEV QELLREGGRI TGVRMQDGIH RCQQVIIASS IWSQALLRTV GYDLPLYPVK GECIAVRTNK PLIRRTIYTD NCYLVPKANG ELLIGATVTP HTMQRHVTVG GILALMGVAE RLIPSIRGAT WIRTWSGLRP QTPQGLPYIG NHPELAGLMI AAGHYRNGIL LSPLTGSVMA DLVEGIELAA DLTAFQVPAM RWSKDQEMTG VGI HMM: 1-29 EQTVDVII VGGGVIGCSI AYHLSKRGIK V ALI: 1-29 EQTVDVII VGGGVIGCSI AYHLSKRGIK V ENV: 1-72 EQTVDVII VGGGVIGCSI AYHLSKRGIK VRLLERGRIA SEASSAAAGM LAAQAEFIDS VPLFDWARQS RAMF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MEWLKEGNE LIPLSWFKDM REQAPLSYDA EHNSWDAFRY EDIKAIFTNH EHFSSQLNDT AEVPIDASIL FLDPPKHRQL RMLVSRAFTP QVIEGLAPKI TAISHELCDQ IEQRGRMDVL HDFASPLPMI VIAEMLGIPA SDRLQFREWS NALVGTSYDA FIQCQQEMSE YFTAIANGRR AAPQQDLISS LVHTHVDGEQ LTDLEIIGFC VLLLVAGNET TTNLISSAML CFDSEPSARE QLAADPSLFP TAIEEVLRYC SPVQKMSRRV KQATELCGQS LEPGQQVDIW IGSANHDPAV FESPNTFNIH RSPNPHLAFG HGIHFCLGAQ LARLEARIAL RILFERFANF RRDQSHMLER AESSMIFGLK SLPFFIA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF00067: 147-372 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
Sequence: MEWLKEGNE LIPLSWFKDM REQAPLSYDA EHNSWDAFRY EDIKAIFTNH EHFSSQLNDT AEVPIDASIL FLDPPKHRQL RMLVSRAFTP QVIEGLAPKI TAISHELCDQ IEQRGRMDVL HDFASPLPMI VIAEMLGIPA SDRLQFREWS NALVGTSYDA FIQCQQEMSE YFTAIANGRR AAPQQDLISS LVHTHVDGEQ LTDLEIIGFC VLLLVAGNET TTNLISSAML CFDSEPSARE QLAADPSLFP TAIEEVLRYC SPVQKMSRRV KQATELCGQS LEPGQQVDIW IGSANHDPAV FESPNTFNIH RSPNPHLAFG HGIHFCLGAQ LARLEARIAL RILFERFANF RRDQSHMLER AESSMIFGLK SLPFFIA HMM: 37-415 RY EDIKAIFTNH EHFSSQLNDT AEVPIDASIL FLDPPKHRQL RMLVSRAFTP QVIEGLAPKI TAISHELCDQ IEQRGRMDVL HDFASPLPMI VIAEMLGIPA SDRLQFREWS NALVGTSYDA FIQCQQEMSE YFTAIANGRR AAPQQDLISS LVHTHVDGEQ LTDLEIIGFC VLLLVAGNET TTNLISSAML CFDSEPSARE QLAADPSLFP TAIEEVLRYC SPVQKMSRRV KQATELCGQS LEPGQQVDIW IGSANHDPAV FESPNTFNIH RSPNPHLAFG HGIHFCLGAQ LARLEARIAL RILFERFANF RRDQSHMLER AESSMIFGLK SLPFFIA ALI: 14-373 WFKDM REQAPLSYDA EHNSWDAFRY EDIKAIFTNH EHFSSQLNDT AEVPIDASIL FLDPPKHRQL RMLVSRAFTP QVIEGLAPKI TAISHELCDQ IEQRGRMDVL HDFASPLPMI VIAEMLGIPA SDRLQFREWS NALVGTSYDA FIQCQQEMSE YFTAIANGRR AAPQQDLISS LVHTHVDGEQ LTDLEIIGFC VLLLVAGNET TTNLISSAML CFDSEPSARE QLAADPSLFP TAIEEVLRYC SPVQKMSRRV KQATELCGQS LEPGQQVDIW IGSANHDPAV FESPNTFNIH RSPNPHLAFG HGIHFCLGAQ LARLEARIAL RILFERFANF RRDQSHMLER AESSMIFGLK SLPFF ENV: 9-376 LIPLSWFKDM REQAPLSYDA EHNSWDAFRY EDIKAIFTNH EHFSSQLNDT AEVPIDASIL FLDPPKHRQL RMLVSRAFTP QVIEGLAPKI TAISHELCDQ IEQRGRMDVL HDFASPLPMI VIAEMLGIPA SDRLQFREWS NALVGTSYDA FIQCQQEMSE YFTAIANGRR AAPQQDLISS LVHTHVDGEQ LTDLEIIGFC VLLLVAGNET TTNLISSAML CFDSEPSARE QLAADPSLFP TAIEEVLRYC SPVQKMSRRV KQATELCGQS LEPGQQVDIW IGSANHDPAV FESPNTFNIH RSPNPHLAFG HGIHFCLGAQ LARLEARIAL RILFERFANF RRDQSHMLER AESSMIFGLK SLPFFIA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MTEHPDDYE KAMENIRNKL ALLPDQPGCY LMKNSEGTII YVGKAKVLKN RVRSYFTGSH DGKTQRLVAD IRDFEYIVTA SNMEALILEC NLIKTHYPRY NVLLKDDKTY PYIKITNDTH PRLEVTRRVL KDKAKYFGPY PNAFAAQQTK KLLDRMYPLR KCVNIPNQAC LYYHIGQCLG PCVEEVTAAQ NEGMIQEITR FLNGGHEEIK RDLQQRMGEA AEALEFERAK ELRDQILSID ALMEKQNITT ADNMDRDVFG YAVDKGWMSV QILYMRQGKM IQRNSSTFPY YGTAYDDFMS FVSQYYSENS ALPREIYLPD DDAADQAAEV SAENGADALE GWLKVKVNIP KRGSKKKLVE MAMQNAKIAL DEKFKLIERD EERSVKAAQN LGEWIGLDSL HRIEAFDNSN IQGTDPVSAM VVFIDGKPAR KEYRKYKIKT VVGPDDYGTM REVIRRRYER VLKENLPMPD LVVVDGGRGQ ISAAVDVLEN ELGLFIPVCG LVKDEKHRTA QLMVGDPAEV VPLKRDSQEF YLLQRIQDEV HRFAITFHRE QRGKSMITSK LDSIPGIGEK RRKALLKHFG SLKKIKEASI EDFRPLSIGE KLASQIIQAL QEES
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
PF01541: 25-100 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
PF02151: 206-239 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
PF08459: 393-544 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF14520: 558-611 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
Sequence: MTEHPDDYE KAMENIRNKL ALLPDQPGCY LMKNSEGTII YVGKAKVLKN RVRSYFTGSH DGKTQRLVAD IRDFEYIVTA SNMEALILEC NLIKTHYPRY NVLLKDDKTY PYIKITNDTH PRLEVTRRVL KDKAKYFGPY PNAFAAQQTK KLLDRMYPLR KCVNIPNQAC LYYHIGQCLG PCVEEVTAAQ NEGMIQEITR FLNGGHEEIK RDLQQRMGEA AEALEFERAK ELRDQILSID ALMEKQNITT ADNMDRDVFG YAVDKGWMSV QILYMRQGKM IQRNSSTFPY YGTAYDDFMS FVSQYYSENS ALPREIYLPD DDAADQAAEV SAENGADALE GWLKVKVNIP KRGSKKKLVE MAMQNAKIAL DEKFKLIERD EERSVKAAQN LGEWIGLDSL HRIEAFDNSN IQGTDPVSAM VVFIDGKPAR KEYRKYKIKT VVGPDDYGTM REVIRRRYER VLKENLPMPD LVVVDGGRGQ ISAAVDVLEN ELGLFIPVCG LVKDEKHRTA QLMVGDPAEV VPLKRDSQEF YLLQRIQDEV HRFAITFHRE QRGKSMITSK LDSIPGIGEK RRKALLKHFG SLKKIKEASI EDFRPLSIGE KLASQIIQAL QEES HMM: 94-145 HYPRY NVLLKDDKTY PYIKITNDTH PRLEVTRRVL KDKAKYFGPY PNAFAAQ ALI: 415-467 VSAM VVFIDGKPAR KEYRKYKIKT VVGPDDYGTM REVIRRRYER VLKENLPMP ENV: 394-471 GLDSL HRIEAFDNSN IQGTDPVSAM VVFIDGKPAR KEYRKYKIKT VVGPDDYGTM REVIRRRYER VLKENLPMPD LVV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MELRLSREQ AHWQNRTRQF AESILVSHAA RMEQVGAFPR ELLMEMRANG LMGIPIPKAW GGEGADFISY ILSIHEISKV SAAAGVILSV HTSVGTLPIL YYGTDEQKKK YVRKLASGDA LGAFALTEPQ AGSDAASIRT TAIREGDYYR LKGSKMFITN AGEADTYITF AVTNASQGAR GISAFIIERD CPGFIVGRAE KKMGLHGSNT CEITLEDVRI PVTQRLGHEG EGFVIAMGTL DGGRIGIAAQ ALGIAQAALE LVEGARIRKG DSLARRRRWS SSELDLFAEL TTQVEAARLL VYRAASMRQA GLPCTKESSM AKMFASDTAM RVTGAVVSML GRQGCTDEYA AERLFRDAKV TQIYEGTNEI HRIVISGSML R
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 6-118 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-217 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 228-378 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MELRLSREQ AHWQNRTRQF AESILVSHAA RMEQVGAFPR ELLMEMRANG LMGIPIPKAW GGEGADFISY ILSIHEISKV SAAAGVILSV HTSVGTLPIL YYGTDEQKKK YVRKLASGDA LGAFALTEPQ AGSDAASIRT TAIREGDYYR LKGSKMFITN AGEADTYITF AVTNASQGAR GISAFIIERD CPGFIVGRAE KKMGLHGSNT CEITLEDVRI PVTQRLGHEG EGFVIAMGTL DGGRIGIAAQ ALGIAQAALE LVEGARIRKG DSLARRRRWS SSELDLFAEL TTQVEAARLL VYRAASMRQA GLPCTKESSM AKMFASDTAM RVTGAVVSML GRQGCTDEYA AERLFRDAKV TQIYEGTNEI HRIVISGSML R HMM: 40-249 LLMEMRANG LMGIPIPKAW GGEGADFISY ILSIHEISKV SAAAGVILSV HTSVGTLPIL YYGTDEQKKK YVRKLASGDA LGAFALTEPQ AGSDAASIRT TAIREGDYYR LKGSKMFITN AGEADTYITF AVTNASQGAR GISAFIIERD CPGFIVGRAE KKMGLHGSNT CEITLEDVRI PVTQRLGHEG EGFVIAMGTL DGGRIGIAAQ A ALI: 33-244 VGAFPR ELLMEMRANG LMGIPIPKAW GGEGADFISY ILSIHEISKV SAAAGVILSV HTSVGTLPIL YYGTDEQKKK YVRKLASGDA LGAFALTEPQ AGSDAASIRT TAIREGDYYR LKGSKMFITN AGEADTYITF AVTNASQGAR GISAFIIERD CPGFIVGRAE KKMGLHGSNT CEITLEDVRI PVTQRLGHEG EGFVIAMGTL DGGRIG ENV: 7-288 EQ AHWQNRTRQF AESILVSHAA RMEQVGAFPR ELLMEMRANG LMGIPIPKAW GGEGADFISY ILSIHEISKV SAAAGVILSV HTSVGTLPIL YYGTDEQKKK YVRKLASGDA LGAFALTEPQ AGSDAASIRT TAIREGDYYR LKGSKMFITN AGEADTYITF AVTNASQGAR GISAFIIERD CPGFIVGRAE KKMGLHGSNT CEITLEDVRI PVTQRLGHEG EGFVIAMGTL DGGRIGIAAQ ALGIAQAALE LVEGARIRKG DSLARRRRWS SSELDLFAEL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MELRLSREQ AHWQNRTRQF AESILVSHAA RMEQVGAFPR ELLMEMRANG LMGIPIPKAW GGEGADFISY ILSIHEISKV SAAAGVILSV HTSVGTLPIL YYGTDEQKKK YVRKLASGDA LGAFALTEPQ AGSDAASIRT TAIREGDYYR LKGSKMFITN AGEADTYITF AVTNASQGAR GISAFIIERD CPGFIVGRAE KKMGLHGSNT CEITLEDVRI PVTQRLGHEG EGFVIAMGTL DGGRIGIAAQ ALGIAQAALE LVEGARIRKG DSLARRRRWS SSELDLFAEL TTQVEAARLL VYRAASMRQA GLPCTKESSM AKMFASDTAM RVTGAVVSML GRQGCTDEYA AERLFRDAKV TQIYEGTNEI HRIVISGSML R HMM: 346-391 EYA AERLFRDAKV TQIYEGTNEI HRIVISGSML R ALI: 318-363 M AKMFASDTAM RVTGAVVSML GRQGCTDEYA AERLFRDAKV TQIYE ENV: 302-373 AASMRQA GLPCTKESSM AKMFASDTAM RVTGAVVSML GRQGCTDEYA AERLFRDAKV TQIYEGTNEI HRIVI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MNTMPSDPF IRNEREQAIA VRSDQLAAIL EQHASLHDRE GSFPFENFEH LREEGYLALT APKEFGGEEA SLYEMILAQE RLARGDGSTA LAVGWHVSQV LQLRIKQSWP QPLYADFCRR VVEEGAMINQ FASEPATGSP SRGGRPQTVA VRTENGYLLT GRKTFSSLLP ILDQFTVTAF IEEENQLGTF YVRKGPGVSM DETWDTIGMR GTGSHDLVLT GAYVPEEHRI NNCENGEVMS DHGGGLLHVP ACYLGIAWAA RDFAIQFAKE YRPNSLPGSI VDLPHIQQKI GEMETERITA RSLLYSVADR WDRLPEERAS MRPELGLAKT VATNAAMRIV DLAMRIVGGS SLSRSLPLER MYRDVRAGLH NPPMDDAVMA MLVQRAIRES
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 28-99 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
PF02770: 130-219 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
PF00441: 249-366 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
Sequence: MNTMPSDPF IRNEREQAIA VRSDQLAAIL EQHASLHDRE GSFPFENFEH LREEGYLALT APKEFGGEEA SLYEMILAQE RLARGDGSTA LAVGWHVSQV LQLRIKQSWP QPLYADFCRR VVEEGAMINQ FASEPATGSP SRGGRPQTVA VRTENGYLLT GRKTFSSLLP ILDQFTVTAF IEEENQLGTF YVRKGPGVSM DETWDTIGMR GTGSHDLVLT GAYVPEEHRI NNCENGEVMS DHGGGLLHVP ACYLGIAWAA RDFAIQFAKE YRPNSLPGSI VDLPHIQQKI GEMETERITA RSLLYSVADR WDRLPEERAS MRPELGLAKT VATNAAMRIV DLAMRIVGGS SLSRSLPLER MYRDVRAGLH NPPMDDAVMA MLVQRAIRES HMM: 19-393 VRSDQLAAIL EQHASLHDRE GSFPFENFEH LREEGYLALT APKEFGGEEA SLYEMILAQE RLARGDGSTA LAVGWHVSQV LQLRIKQSWP QPLYADFCRR VVEEGAMINQ FASEPATGSP SRGGRPQTVA VRTENGYLLT GRKTFSSLLP ILDQFTVTAF IEEENQLGTF YVRKGPGVSM DETWDTIGMR GTGSHDLVLT GAYVPEEHRI NNCENGEVMS DHGGGLLHVP ACYLGIAWAA RDFAIQFAKE YRPNSLPGSI VDLPHIQQKI GEMETERITA RSLLYSVADR WDRLPEERAS MRPELGLAKT VATNAAMRIV DLAMRIVGGS SLSRSLPLER MYRDVRAGLH NPPMDDAVMA MLVQRAIRES ALI: 16-371 AIA VRSDQLAAIL EQHASLHDRE GSFPFENFEH LREEGYLALT APKEFGGEEA SLYEMILAQE RLARGDGSTA LAVGWHVSQV LQLRIKQSWP QPLYADFCRR VVEEGAMINQ FASEPATGSP SRGGRPQTVA VRTENGYLLT GRKTFSSLLP ILDQFTVTAF IEEENQLGTF YVRKGPGVSM DETWDTIGMR GTGSHDLVLT GAYVPEEHRI NNCENGEVMS DHGGGLLHVP ACYLGIAWAA RDFAIQFAKE YRPNSLPGSI VDLPHIQQKI GEMETERITA RSLLYSVADR WDRLPEERAS MRPELGLAKT VATNAAMRIV DLAMRIVGGS SLSRSLPLER MYRDVRAGLH NPP ENV: 9-379 IRNEREQAIA VRSDQLAAIL EQHASLHDRE GSFPFENFEH LREEGYLALT APKEFGGEEA SLYEMILAQE RLARGDGSTA LAVGWHVSQV LQLRIKQSWP QPLYADFCRR VVEEGAMINQ FASEPATGSP SRGGRPQTVA VRTENGYLLT GRKTFSSLLP ILDQFTVTAF IEEENQLGTF YVRKGPGVSM DETWDTIGMR GTGSHDLVLT GAYVPEEHRI NNCENGEVMS DHGGGLLHVP ACYLGIAWAA RDFAIQFAKE YRPNSLPGSI VDLPHIQQKI GEMETERITA RSLLYSVADR WDRLPEERAS MRPELGLAKT VATNAAMRIV DLAMRIVGGS SLSRSLPLER MYRDVRAGLH NPPMDDAVMA M Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MQFLGSEEL EMTRSVLRDF ARSELMPRVK ERDEHQLFDR ALVRKMADIG LTGMLIPEHY GGAAGDYLTF AVVMEELAAV CVSSAAVLGA HTAFTSWVIH SSGTERLKWE HMHGLAQGLK LGGIGFPVRH VGGEDQDTLL SAHKSGDVHV LQGNHPCVVN AGIADLYILF ARVQSGSRKR YQAYVVEKST MGFEIGKPHR KIGLRSYPTA NVVLKQCVLP EINRLGRASH SNSKAVLWGD LTYLSAAAMA VGIAQGAVDR AAAYARERVQ FGRAIGRQQG IAFKLADMAV KLEAARMLTY QAAWNMDQRL PSRREAAMAR MYSAEAAVSI TTEAVQIFGG YGYMQEVGLE RYMRDAKCLE SDYGTGGFQS DVRSRIRMNS KAVK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-117 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 132-216 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 243-367 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MQFLGSEEL EMTRSVLRDF ARSELMPRVK ERDEHQLFDR ALVRKMADIG LTGMLIPEHY GGAAGDYLTF AVVMEELAAV CVSSAAVLGA HTAFTSWVIH SSGTERLKWE HMHGLAQGLK LGGIGFPVRH VGGEDQDTLL SAHKSGDVHV LQGNHPCVVN AGIADLYILF ARVQSGSRKR YQAYVVEKST MGFEIGKPHR KIGLRSYPTA NVVLKQCVLP EINRLGRASH SNSKAVLWGD LTYLSAAAMA VGIAQGAVDR AAAYARERVQ FGRAIGRQQG IAFKLADMAV KLEAARMLTY QAAWNMDQRL PSRREAAMAR MYSAEAAVSI TTEAVQIFGG YGYMQEVGLE RYMRDAKCLE SDYGTGGFQS DVRSRIRMNS KAVK HMM: 37-386 DR ALVRKMADIG LTGMLIPEHY GGAAGDYLTF AVVMEELAAV CVSSAAVLGA HTAFTSWVIH SSGTERLKWE HMHGLAQGLK LGGIGFPVRH VGGEDQDTLL SAHKSGDVHV LQGNHPCVVN AGIADLYILF ARVQSGSRKR YQAYVVEKST MGFEIGKPHR KIGLRSYPTA NVVLKQCVLP EINRLGRASH SNSKAVLWGD LTYLSAAAMA VGIAQGAVDR AAAYARERVQ FGRAIGRQQG IAFKLADMAV KLEAARMLTY QAAWNMDQRL PSRREAAMAR MYSAEAAVSI TTEAVQIFGG YGYMQEVGLE RYMRDAKCLE SDYGTGGFQS DVRSRIRMNS KAVK ALI: 30-356 RDEHQLFDR ALVRKMADIG LTGMLIPEHY GGAAGDYLTF AVVMEELAAV CVSSAAVLGA HTAFTSWVIH SSGTERLKWE HMHGLAQGLK LGGIGFPVRH VGGEDQDTLL SAHKSGDVHV LQGNHPCVVN AGIADLYILF ARVQSGSRKR YQAYVVEKST MGFEIGKPHR KIGLRSYPTA NVVLKQCVLP EINRLGRASH SNSKAVLWGD LTYLSAAAMA VGIAQGAVDR AAAYARERVQ FGRAIGRQQG IAFKLADMAV KLEAARMLTY QAAWNMDQRL PSRREAAMAR MYSAEAAVSI TTEAVQIFGG YGYMQEVGLE RYMRDAKC ENV: 11-361 TRSVLRDF ARSELMPRVK ERDEHQLFDR ALVRKMADIG LTGMLIPEHY GGAAGDYLTF AVVMEELAAV CVSSAAVLGA HTAFTSWVIH SSGTERLKWE HMHGLAQGLK LGGIGFPVRH VGGEDQDTLL SAHKSGDVHV LQGNHPCVVN AGIADLYILF ARVQSGSRKR YQAYVVEKST MGFEIGKPHR KIGLRSYPTA NVVLKQCVLP EINRLGRASH SNSKAVLWGD LTYLSAAAMA VGIAQGAVDR AAAYARERVQ FGRAIGRQQG IAFKLADMAV KLEAARMLTY QAAWNMDQRL PSRREAAMAR MYSAEAAVSI TTEAVQIFGG YGYMQEVGLE RYMRDAKCLE SDY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MGKVIDRII GGSFVIEDIS PDRIVTPEDF TEEQRMFVET TKQFLQTDVL PQDEQLEKLD YELTVKLMRK AGELGLLSSD IPEIYGGLGL DKVSSTIINE VLAGASSFAL SVGAHVGIGT LPIVFFGTPE QKARYLPDLA TGAKIAAYCL TEPTSGSDAL GAKTTAKLSD DGQHYILNGS KVFITNAGFA DLFIVYAKVD GQHFSAFIVE KDTPGFTLGP EEKKMGIKGS STRPLFFEEA HVPVDNLLGE IGKGHLIAFN ILNIGRFKLG AGCLGGAKEA IHIAAQYANV RTQFGKPIAS FPLIGKKLAE MNITTYVMES MVYRTAGYID HILSDLDHTS PDAGKQSAKG ISEYALECSI NKVFASEALD FVADEGVQIH GGYGFIQEYK IERIYRDSRI NRIFEGTNEI NRLLIPGTLL KKALKGELPL IQKAEALQSE LLQLIPGQTF DGVLEQERHL LSMAKKIFLF AGGVAIQKVG TRIEAEQEIL SSLADMMIQI YALESALLRA EKQVARSSEA ESLNYIQMTQ VFAQEAFERI ESEAKITLST LETGDVLRTQ LSILKKLARH TPVNTTQLKR AIGARVIHGE KYQS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590
PF02771: 29-141 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
PF02770: 145-238 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 250-414 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌
Sequence: MGKVIDRII GGSFVIEDIS PDRIVTPEDF TEEQRMFVET TKQFLQTDVL PQDEQLEKLD YELTVKLMRK AGELGLLSSD IPEIYGGLGL DKVSSTIINE VLAGASSFAL SVGAHVGIGT LPIVFFGTPE QKARYLPDLA TGAKIAAYCL TEPTSGSDAL GAKTTAKLSD DGQHYILNGS KVFITNAGFA DLFIVYAKVD GQHFSAFIVE KDTPGFTLGP EEKKMGIKGS STRPLFFEEA HVPVDNLLGE IGKGHLIAFN ILNIGRFKLG AGCLGGAKEA IHIAAQYANV RTQFGKPIAS FPLIGKKLAE MNITTYVMES MVYRTAGYID HILSDLDHTS PDAGKQSAKG ISEYALECSI NKVFASEALD FVADEGVQIH GGYGFIQEYK IERIYRDSRI NRIFEGTNEI NRLLIPGTLL KKALKGELPL IQKAEALQSE LLQLIPGQTF DGVLEQERHL LSMAKKIFLF AGGVAIQKVG TRIEAEQEIL SSLADMMIQI YALESALLRA EKQVARSSEA ESLNYIQMTQ VFAQEAFERI ESEAKITLST LETGDVLRTQ LSILKKLARH TPVNTTQLKR AIGARVIHGE KYQS HMM: 55-233 EKLD YELTVKLMRK AGELGLLSSD IPEIYGGLGL DKVSSTIINE VLAGASSFAL SVGAHVGIGT LPIVFFGTPE QKARYLPDLA TGAKIAAYCL TEPTSGSDAL GAKTTAKLSD DGQHYILNGS KVFITNAGFA DLFIVYAKVD GQHFSAFIVE KDTPGFTLGP EEKKMGIKGS STRPL ALI: 73-249 GLLSSD IPEIYGGLGL DKVSSTIINE VLAGASSFAL SVGAHVGIGT LPIVFFGTPE QKARYLPDLA TGAKIAAYCL TEPTSGSDAL GAKTTAKLSD DGQHYILNGS KVFITNAGFA DLFIVYAKVD GQHFSAFIVE KDTPGFTLGP EEKKMGIKGS STRPLFFEEA HVPVDNLLGE I ENV: 64-406 KLMRK AGELGLLSSD IPEIYGGLGL DKVSSTIINE VLAGASSFAL SVGAHVGIGT LPIVFFGTPE QKARYLPDLA TGAKIAAYCL TEPTSGSDAL GAKTTAKLSD DGQHYILNGS KVFITNAGFA DLFIVYAKVD GQHFSAFIVE KDTPGFTLGP EEKKMGIKGS STRPLFFEEA HVPVDNLLGE IGKGHLIAFN ILNIGRFKLG AGCLGGAKEA IHIAAQYANV RTQFGKPIAS FPLIGKKLAE MNITTYVMES MVYRTAGYID HILSDLDHTS PDAGKQSAKG ISEYALECSI NKVFASEALD FVADEGVQIH GGYGFIQEYK IERIYRDSRI NRIFEGTN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590
Sequence: MDKYICTVC SYIYDPEAGD PDSGIAPGTS FEDIPDDWVC PLCGVGKDSF EKYTE
10 20 30 40 50
PF00301: 2-49 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MDKYICTVC SYIYDPEAGD PDSGIAPGTS FEDIPDDWVC PLCGVGKDSF EKYTE HMM: 425-469 ALI: 3-47 YICTVC SYIYDPEAGD PDSGIAPGTS FEDIPDDWVC PLCGVGKDS ENV: 1-54 DKYICTVC SYIYDPEAGD PDSGIAPGTS FEDIPDDWVC PLCGVGKDSF EKYTE Position: 10 20 30 40 50
Sequence: MELSYEIIL AYMVGIIFLF FIGRLFLVPL KILLKLVYNC ILGAILLIVV NYIGRTFGFS IPLNIFSAAL VGFLGIPGML LLVALKVLYF
10 20 30 40 50 60 70 80
PF07441: 12-86 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
Sequence: MELSYEIIL AYMVGIIFLF FIGRLFLVPL KILLKLVYNC ILGAILLIVV NYIGRTFGFS IPLNIFSAAL VGFLGIPGML LLVALKVLYF HMM: 229-273 ALI: 6-52 IIL AYMVGIIFLF FIGRLFLVPL KILLKLVYNC ILGAILLIVV NYIG ENV: 1-54 ELSYEIIL AYMVGIIFLF FIGRLFLVPL KILLKLVYNC ILGAILLIVV NYIGRT Position: 10 20 30 40 50 60 70 80
Sequence: MELSINART KIIGIIGDPI EHSKSPILHN YISASKNINA VYVPFRVHTD NLLDAVRGLR GLNVVGFNVT VPHKNKVMEY LDCISEEARL IGAVNTVKNI DGKLWGYNTD GDGFLRSFKE ETGHSFKGER VVIIGAGGAA RAVAVKVALE GASEVVILNR SVDKAKELSD YINNNISCCS SFAGMEHSDV KNAVMNCRIV INTTSVGMYP EIDKSPIESY SLLNDKHIVY DIIYNPVKTE LLKAAGEKGS IAVNGMGMLF YQGIYAYEKW MDIEFLENEI EQFYMRFKET VMAI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290
PF08501: 13-96 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
PF01488: 122-205 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MELSINART KIIGIIGDPI EHSKSPILHN YISASKNINA VYVPFRVHTD NLLDAVRGLR GLNVVGFNVT VPHKNKVMEY LDCISEEARL IGAVNTVKNI DGKLWGYNTD GDGFLRSFKE ETGHSFKGER VVIIGAGGAA RAVAVKVALE GASEVVILNR SVDKAKELSD YINNNISCCS SFAGMEHSDV KNAVMNCRIV INTTSVGMYP EIDKSPIESY SLLNDKHIVY DIIYNPVKTE LLKAAGEKGS IAVNGMGMLF YQGIYAYEKW MDIEFLENEI EQFYMRFKET VMAI HMM: 174-211 ISCCS SFAGMEHSDV KNAVMNCRIV INTTSVGMYP EID ALI: 123-161 SFKGER VVIIGAGGAA RAVAVKVALE GASEVVILNR SVD ENV: 113-176 LRSFKE ETGHSFKGER VVIIGAGGAA RAVAVKVALE GASEVVILNR SVDKAKELSD YINNNISC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290
Sequence: MELSINART KIIGIIGDPI EHSKSPILHN YISASKNINA VYVPFRVHTD NLLDAVRGLR GLNVVGFNVT VPHKNKVMEY LDCISEEARL IGAVNTVKNI DGKLWGYNTD GDGFLRSFKE ETGHSFKGER VVIIGAGGAA RAVAVKVALE GASEVVILNR SVDKAKELSD YINNNISCCS SFAGMEHSDV KNAVMNCRIV INTTSVGMYP EIDKSPIESY SLLNDKHIVY DIIYNPVKTE LLKAAGEKGS IAVNGMGMLF YQGIYAYEKW MDIEFLENEI EQFYMRFKET VMAI HMM: 173-210 NISCCS SFAGMEHSDV KNAVMNCRIV INTTSVGMYP EI ALI: 124-161 FKGER VVIIGAGGAA RAVAVKVALE GASEVVILNR SVD ENV: 114-173 RSFKE ETGHSFKGER VVIIGAGGAA RAVAVKVALE GASEVVILNR SVDKAKELSD YINNN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290
Sequence: MSEFYTVCD STNFEEVISK SQVPVVAYFY SDDCLPCTKF SQIFERSAVT LAEQLKFVKV FRPHNRQLAE KYSVKSSPTI IFFKEGREVC SRLNGYISFP EFKEAIENVL EKTCDSKERT IVHCDVLIIG AGPAGLTAAI YASRSKLHTI VVDSSLPGGQ VASTYHISNY PGTNGVIRGI DLMENMKKQA LDFGSQIDDM QSIKSINLTG DEKYIQTETN DYYAKSIIIA TGAEPRKLPV ESEREYRGRG IHYCATCDGA LYTDANVIVV GGELQQLKNR CSSLDMQKAL R
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290
PF00085: 7-94 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
PF07992: 123-271 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌
Sequence: MSEFYTVCD STNFEEVISK SQVPVVAYFY SDDCLPCTKF SQIFERSAVT LAEQLKFVKV FRPHNRQLAE KYSVKSSPTI IFFKEGREVC SRLNGYISFP EFKEAIENVL EKTCDSKERT IVHCDVLIIG AGPAGLTAAI YASRSKLHTI VVDSSLPGGQ VASTYHISNY PGTNGVIRGI DLMENMKKQA LDFGSQIDDM QSIKSINLTG DEKYIQTETN DYYAKSIIIA TGAEPRKLPV ESEREYRGRG IHYCATCDGA LYTDANVIVV GGELQQLKNR CSSLDMQKAL R HMM: 5-54 TVCD STNFEEVISK SQVPVVAYFY SDDCLPCTKF SQIFERSAVT LAEQLK ALI: 122-172 CDVLIIG AGPAGLTAAI YASRSKLHTI VVDSSLPGGQ VASTYHISNY PGTN ENV: 118-220 T IVHCDVLIIG AGPAGLTAAI YASRSKLHTI VVDSSLPGGQ VASTYHISNY PGTNGVIRGI DLMENMKKQA LDFGSQIDDM QSIKSINLTG DEKYIQTETN DY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290
Sequence: MNSKYKEGK WCKGIDVRDF IQKNYTPYDG DESFLAQPTE STIKLWSKVK ELMKIERERG GIIDIDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRMV RSSLKAYDRP MDPNVENVFK YRKTHNDGVF DAYTDEMKKA RHTGIITGLP DSYGRGRIIG DYRRVALYGV DYLIQKKKEA KSNYVFDIMN SPIIRQREEI SEQIRALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
PF02901: 14-598 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF01228: 613-720 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MNSKYKEGK WCKGIDVRDF IQKNYTPYDG DESFLAQPTE STIKLWSKVK ELMKIERERG GIIDIDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRMV RSSLKAYDRP MDPNVENVFK YRKTHNDGVF DAYTDEMKKA RHTGIITGLP DSYGRGRIIG DYRRVALYGV DYLIQKKKEA KSNYVFDIMN SPIIRQREEI SEQIRALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF HMM: 288-426 E IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSL ALI: 230-369 GRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF K ENV: 202-379 IRQREEI SEQIRALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE T Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MNSKYKEGK WCKGIDVRDF IQKNYTPYDG DESFLAQPTE STIKLWSKVK ELMKIERERG GIIDIDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRMV RSSLKAYDRP MDPNVENVFK YRKTHNDGVF DAYTDEMKKA RHTGIITGLP DSYGRGRIIG DYRRVALYGV DYLIQKKKEA KSNYVFDIMN SPIIRQREEI SEQIRALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF HMM: 483-564 YMHDKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDL ALI: 411-493 KQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERI ENV: 397-507 DY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MNSKYKEGK WCKGIDVRDF IQKNYTPYDG DESFLAQPTE STIKLWSKVK ELMKIERERG GIIDIDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRMV RSSLKAYDRP MDPNVENVFK YRKTHNDGVF DAYTDEMKKA RHTGIITGLP DSYGRGRIIG DYRRVALYGV DYLIQKKKEA KSNYVFDIMN SPIIRQREEI SEQIRALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF HMM: 644-831 EDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF ALI: 548-736 P KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHE ENV: 540-737 DYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHER Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MNSKYKEGK WCKGIDVRDF IQKNYTPYDG DESFLAQPTE STIKLWSKVK ELMKIERERG GIIDIDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRMV RSSLKAYDRP MDPNVENVFK YRKTHNDGVF DAYTDEMKKA RHTGIITGLP DSYGRGRIIG DYRRVALYGV DYLIQKKKEA KSNYVFDIMN SPIIRQREEI SEQIRALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF HMM: 299-439 MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT G ALI: 233-371 AQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKY ENV: 214-393 ALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MNSKYKEGK WCKGIDVRDF IQKNYTPYDG DESFLAQPTE STIKLWSKVK ELMKIERERG GIIDIDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRMV RSSLKAYDRP MDPNVENVFK YRKTHNDGVF DAYTDEMKKA RHTGIITGLP DSYGRGRIIG DYRRVALYGV DYLIQKKKEA KSNYVFDIMN SPIIRQREEI SEQIRALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF HMM: 514-581 SVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDS ALI: 423-490 AKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CY ENV: 402-504 CCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MNSKYKEGK WCKGIDVRDF IQKNYTPYDG DESFLAQPTE STIKLWSKVK ELMKIERERG GIIDIDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRMV RSSLKAYDRP MDPNVENVFK YRKTHNDGVF DAYTDEMKKA RHTGIITGLP DSYGRGRIIG DYRRVALYGV DYLIQKKKEA KSNYVFDIMN SPIIRQREEI SEQIRALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF HMM: 662-846 DDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF ALI: 548-734 P KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTF ENV: 537-738 LI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MNSKYKEGK WCKGIDVRDF IQKNYTPYDG DESFLAQPTE STIKLWSKVK ELMKIERERG GIIDIDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRMV RSSLKAYDRP MDPNVENVFK YRKTHNDGVF DAYTDEMKKA RHTGIITGLP DSYGRGRIIG DYRRVALYGV DYLIQKKKEA KSNYVFDIMN SPIIRQREEI SEQIRALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF HMM: 63-103 IDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFG ALI: 66-107 KTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRM ENV: 49-132 ELMKIERERG GIIDIDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRMV RSSLKAYDRP MDPNVENVFK YRKT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MNSKYKEGK WCKGIDVRDF IQKNYTPYDG DESFLAQPTE STIKLWSKVK ELMKIERERG GIIDIDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRMV RSSLKAYDRP MDPNVENVFK YRKTHNDGVF DAYTDEMKKA RHTGIITGLP DSYGRGRIIG DYRRVALYGV DYLIQKKKEA KSNYVFDIMN SPIIRQREEI SEQIRALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF HMM: 486-556 DKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPV ALI: 424-494 KSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQ ENV: 408-509 K LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSAC G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MNSKYKEGK WCKGIDVRDF IQKNYTPYDG DESFLAQPTE STIKLWSKVK ELMKIERERG GIIDIDTKTI STIISHEPGY IDKEIEKIVG LQADEPLKRT IMPFGGIRMV RSSLKAYDRP MDPNVENVFK YRKTHNDGVF DAYTDEMKKA RHTGIITGLP DSYGRGRIIG DYRRVALYGV DYLIQKKKEA KSNYVFDIMN SPIIRQREEI SEQIRALEEL KFMAASYGYD IGRPAQNTLE AIQWLYFGYL AAVKEQNGAA MSLGRVSTFL DIYSEKDLEE GRFTEEQIQE IVDHFVMKLR MVRFLRTPAY DELFSGDPTW ITEAFAGMGL DGRHMVTKMS YRFLHTLVNL GPAPEPNMTV LWSSKLPQNF KKYCAKLSIE TSSIQYENDD LMKEKFGDDY GIACCVSAMK LGKQMQFFGA RANLAKSLLY AINGGKDEIT GEQVGPLIAP ITSEYLDYEE VMQRFDMTMD WLSKLYINTL NIIHYMHDKY CYERIQMALH DEEILRTSAC GLAGLSVVVD SLSAIKHAKV RAIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF HMM: 633-818 ASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF ALI: 548-735 P KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFH ENV: 530-738 AIRNEQGLI TDYDIEGDYP KFGNNDPVVD DIAVDLVKTF MNKLSKHKTY RDSKPTMSIL TITSNVVYGK KTGSTPDGRK LGEPFAPGAN PMHNRDTKGC IASMASVSKI PFNYSEDGIS YTFSIVPSAL GKTDDDKLDN LVSLMDGYFD ESGHHINVNV LNKEVLIDAM EHPEEYPQLT IRVSGYAVNF IKLTREQQID VINRTFHERF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730
Sequence: MTWNYWNGF MGLDWKQRID LRGFIVENYK PYDGDDSFLA KATFKTRRLW DRCKELIGEE SKKGGVLDIE TDIISGINSF APGYIDQGLE VIKGIQTDKP LKRAVVPYGG IRMAKQACEK YGYKLSDKIE EVFTNYSKTH NDGVFDVYTP EMKKARKSGV ITGLPDAYGR GRLIGDYRRV ALYGVDKLIE EKSKELSELV PSVFDESILR SREELQEQIK SLNELKLMAN SYGFDISKPA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVSIDTCTLQ YENDDIMRPA FGDDYGISCC VSAMRIGRDM QYFGARCNLP KLLLMALNGG RDEVTGDQVA PLSAPYEGEY LDYKTVLNKY EELQEWLAGL YVNTMNAIHY MHDKYAYERL MMALHDTDVR RFMAFGIAGL SVIADSLSAI KYGKVKAIRD ERGIITDFEI EGDFPKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGEI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
PF02901: 15-603 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF01228: 618-725 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MTWNYWNGF MGLDWKQRID LRGFIVENYK PYDGDDSFLA KATFKTRRLW DRCKELIGEE SKKGGVLDIE TDIISGINSF APGYIDQGLE VIKGIQTDKP LKRAVVPYGG IRMAKQACEK YGYKLSDKIE EVFTNYSKTH NDGVFDVYTP EMKKARKSGV ITGLPDAYGR GRLIGDYRRV ALYGVDKLIE EKSKELSELV PSVFDESILR SREELQEQIK SLNELKLMAN SYGFDISKPA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVSIDTCTLQ YENDDIMRPA FGDDYGISCC VSAMRIGRDM QYFGARCNLP KLLLMALNGG RDEVTGDQVA PLSAPYEGEY LDYKTVLNKY EELQEWLAGL YVNTMNAIHY MHDKYAYERL MMALHDTDVR RFMAFGIAGL SVIADSLSAI KYGKVKAIRD ERGIITDFEI EGDFPKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGEI HMM: 275-420 IYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVSIDTCTLQ YENDDIMRPA FGDDYGISCC VSAMRIGRDM QY ALI: 222-368 ELKLMAN SYGFDISKPA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG ENV: 209-378 SREELQEQIK SLNELKLMAN SYGFDISKPA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MTWNYWNGF MGLDWKQRID LRGFIVENYK PYDGDDSFLA KATFKTRRLW DRCKELIGEE SKKGGVLDIE TDIISGINSF APGYIDQGLE VIKGIQTDKP LKRAVVPYGG IRMAKQACEK YGYKLSDKIE EVFTNYSKTH NDGVFDVYTP EMKKARKSGV ITGLPDAYGR GRLIGDYRRV ALYGVDKLIE EKSKELSELV PSVFDESILR SREELQEQIK SLNELKLMAN SYGFDISKPA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVSIDTCTLQ YENDDIMRPA FGDDYGISCC VSAMRIGRDM QYFGARCNLP KLLLMALNGG RDEVTGDQVA PLSAPYEGEY LDYKTVLNKY EELQEWLAGL YVNTMNAIHY MHDKYAYERL MMALHDTDVR RFMAFGIAGL SVIADSLSAI KYGKVKAIRD ERGIITDFEI EGDFPKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGEI HMM: 475-569 LAGL YVNTMNAIHY MHDKYAYERL MMALHDTDVR RFMAFGIAGL SVIADSLSAI KYGKVKAIRD ERGIITDFEI EGDFPKYGND DDRVDKIAVS I ALI: 408-503 C VSAMRIGRDM QYFGARCNLP KLLLMALNGG RDEVTGDQVA PLSAPYEGEY LDYKTVLNKY EELQEWLAGL YVNTMNAIHY MHDKYAYERL MMALH ENV: 402-512 DYGISCC VSAMRIGRDM QYFGARCNLP KLLLMALNGG RDEVTGDQVA PLSAPYEGEY LDYKTVLNKY EELQEWLAGL YVNTMNAIHY MHDKYAYERL MMALHDTDVR RFMA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MTWNYWNGF MGLDWKQRID LRGFIVENYK PYDGDDSFLA KATFKTRRLW DRCKELIGEE SKKGGVLDIE TDIISGINSF APGYIDQGLE VIKGIQTDKP LKRAVVPYGG IRMAKQACEK YGYKLSDKIE EVFTNYSKTH NDGVFDVYTP EMKKARKSGV ITGLPDAYGR GRLIGDYRRV ALYGVDKLIE EKSKELSELV PSVFDESILR SREELQEQIK SLNELKLMAN SYGFDISKPA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVSIDTCTLQ YENDDIMRPA FGDDYGISCC VSAMRIGRDM QYFGARCNLP KLLLMALNGG RDEVTGDQVA PLSAPYEGEY LDYKTVLNKY EELQEWLAGL YVNTMNAIHY MHDKYAYERL MMALHDTDVR RFMAFGIAGL SVIADSLSAI KYGKVKAIRD ERGIITDFEI EGDFPKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGEI HMM: 644-831 PYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGEI ALI: 553-741 PKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHG ENV: 545-742 DFEI EGDFPKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MTWNYWNGF MGLDWKQRID LRGFIVENYK PYDGDDSFLA KATFKTRRLW DRCKELIGEE SKKGGVLDIE TDIISGINSF APGYIDQGLE VIKGIQTDKP LKRAVVPYGG IRMAKQACEK YGYKLSDKIE EVFTNYSKTH NDGVFDVYTP EMKKARKSGV ITGLPDAYGR GRLIGDYRRV ALYGVDKLIE EKSKELSELV PSVFDESILR SREELQEQIK SLNELKLMAN SYGFDISKPA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVSIDTCTLQ YENDDIMRPA FGDDYGISCC VSAMRIGRDM QYFGARCNLP KLLLMALNGG RDEVTGDQVA PLSAPYEGEY LDYKTVLNKY EELQEWLAGL YVNTMNAIHY MHDKYAYERL MMALHDTDVR RFMAFGIAGL SVIADSLSAI KYGKVKAIRD ERGIITDFEI EGDFPKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGEI HMM: 298-431 F IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVSIDTCTLQ YENDDIMRPA FGDDYGISCC VSAMRIGRDM QYFGARCNLP KLL ALI: 237-368 PA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG ENV: 211-381 EELQEQIK SLNELKLMAN SYGFDISKPA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MTWNYWNGF MGLDWKQRID LRGFIVENYK PYDGDDSFLA KATFKTRRLW DRCKELIGEE SKKGGVLDIE TDIISGINSF APGYIDQGLE VIKGIQTDKP LKRAVVPYGG IRMAKQACEK YGYKLSDKIE EVFTNYSKTH NDGVFDVYTP EMKKARKSGV ITGLPDAYGR GRLIGDYRRV ALYGVDKLIE EKSKELSELV PSVFDESILR SREELQEQIK SLNELKLMAN SYGFDISKPA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVSIDTCTLQ YENDDIMRPA FGDDYGISCC VSAMRIGRDM QYFGARCNLP KLLLMALNGG RDEVTGDQVA PLSAPYEGEY LDYKTVLNKY EELQEWLAGL YVNTMNAIHY MHDKYAYERL MMALHDTDVR RFMAFGIAGL SVIADSLSAI KYGKVKAIRD ERGIITDFEI EGDFPKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGEI HMM: 662-846 ALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGEI ALI: 553-739 PKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT F ENV: 541-742 GIITDFEI EGDFPKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MTWNYWNGF MGLDWKQRID LRGFIVENYK PYDGDDSFLA KATFKTRRLW DRCKELIGEE SKKGGVLDIE TDIISGINSF APGYIDQGLE VIKGIQTDKP LKRAVVPYGG IRMAKQACEK YGYKLSDKIE EVFTNYSKTH NDGVFDVYTP EMKKARKSGV ITGLPDAYGR GRLIGDYRRV ALYGVDKLIE EKSKELSELV PSVFDESILR SREELQEQIK SLNELKLMAN SYGFDISKPA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVSIDTCTLQ YENDDIMRPA FGDDYGISCC VSAMRIGRDM QYFGARCNLP KLLLMALNGG RDEVTGDQVA PLSAPYEGEY LDYKTVLNKY EELQEWLAGL YVNTMNAIHY MHDKYAYERL MMALHDTDVR RFMAFGIAGL SVIADSLSAI KYGKVKAIRD ERGIITDFEI EGDFPKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGEI HMM: 329-408 GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVSIDTCTLQ YENDDIMRPA FGDDYGISCC ALI: 287-367 TE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSN ENV: 275-376 IYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MTWNYWNGF MGLDWKQRID LRGFIVENYK PYDGDDSFLA KATFKTRRLW DRCKELIGEE SKKGGVLDIE TDIISGINSF APGYIDQGLE VIKGIQTDKP LKRAVVPYGG IRMAKQACEK YGYKLSDKIE EVFTNYSKTH NDGVFDVYTP EMKKARKSGV ITGLPDAYGR GRLIGDYRRV ALYGVDKLIE EKSKELSELV PSVFDESILR SREELQEQIK SLNELKLMAN SYGFDISKPA QNAYEAFQWT YLAFLGAMKE TNGAANSLGR MSTFFDIYIE RDIKEGKLTE DEAQELVDQF IIKLRMIRHL RTPEYNELFA GDPVWITESI GGMCEDGRHM VTKTSYRFLQ SLYNIGSSPE PNLTILWSNG LPTNFKNFCA KVSIDTCTLQ YENDDIMRPA FGDDYGISCC VSAMRIGRDM QYFGARCNLP KLLLMALNGG RDEVTGDQVA PLSAPYEGEY LDYKTVLNKY EELQEWLAGL YVNTMNAIHY MHDKYAYERL MMALHDTDVR RFMAFGIAGL SVIADSLSAI KYGKVKAIRD ERGIITDFEI EGDFPKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGEI HMM: 633-817 ILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGEI ALI: 553-739 PKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT F ENV: 522-742 ADSLSAI KYGKVKAIRD ERGIITDFEI EGDFPKYGND DDRVDKIAVS IVKNFYKSLE KHKTLRGAKH TLSVLTITSN VVYGSKTGST PDGRIKGEAF APGANPMHGR DTNGILASLN TLAKIPYEYC LDGISYTLSI IPHALGKSAN SRVTNLAGIL AGYFALGGHH VNINIMERSI LEEAMKDPAK YPQMTVRVSG YAVNFNRLSK KQQLEVVNRT FHGE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MKIELTEEQ IKRQAEFRSF VDNEISPYAG QNDLMETVAD EIINKVIERG YLGSMISSTY GGQGMDMLTI GILNEEIGRG CSSIRSLLTV HGMVAMAIER WGSREQKEYW LPKMARGEII GAFGLSEPNV GSDAKSVETT AVLEGEHYIL NGRKKWTTMG QIANVFLIIA LTEGKPTAFL VDKNSPGFST KPMKGLMGSR ASMIAELFMD NCLIPKDNII GSIGTGLSHI ALSSLDYGRY TIACGCVGLA QACLEESIMY CRKRKQFGAP LRQNQLIQKM ITEMVVNIKA ARLLCWSAGY MKEAGDPDSI MEVWNAKYFA SIMANKVASD AVQIHGANGC CRDYPVERYY RDAKINEIIE GTTQMHEVLI ATNAFRGM
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-117 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 120-211 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF00441: 228-372 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
Sequence: MKIELTEEQ IKRQAEFRSF VDNEISPYAG QNDLMETVAD EIINKVIERG YLGSMISSTY GGQGMDMLTI GILNEEIGRG CSSIRSLLTV HGMVAMAIER WGSREQKEYW LPKMARGEII GAFGLSEPNV GSDAKSVETT AVLEGEHYIL NGRKKWTTMG QIANVFLIIA LTEGKPTAFL VDKNSPGFST KPMKGLMGSR ASMIAELFMD NCLIPKDNII GSIGTGLSHI ALSSLDYGRY TIACGCVGLA QACLEESIMY CRKRKQFGAP LRQNQLIQKM ITEMVVNIKA ARLLCWSAGY MKEAGDPDSI MEVWNAKYFA SIMANKVASD AVQIHGANGC CRDYPVERYY RDAKINEIIE GTTQMHEVLI ATNAFRGM HMM: 52-175 SMISSTY GGQGMDMLTI GILNEEIGRG CSSIRSLLTV HGMVAMAIER WGSREQKEYW LPKMARGEII GAFGLSEPNV GSDAKSVETT AVLEGEHYIL NGRKKWTTMG QIANVFLIIA LTEGKPT ALI: 45-169 IERG YLGSMISSTY GGQGMDMLTI GILNEEIGRG CSSIRSLLTV HGMVAMAIER WGSREQKEYW LPKMARGEII GAFGLSEPNV GSDAKSVETT AVLEGEHYIL NGRKKWTTMG QIANVFLIIA L ENV: 29-177 QNDLMETVAD EIINKVIERG YLGSMISSTY GGQGMDMLTI GILNEEIGRG CSSIRSLLTV HGMVAMAIER WGSREQKEYW LPKMARGEII GAFGLSEPNV GSDAKSVETT AVLEGEHYIL NGRKKWTTMG QIANVFLIIA LTEGKPTAF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MKIELTEEQ IKRQAEFRSF VDNEISPYAG QNDLMETVAD EIINKVIERG YLGSMISSTY GGQGMDMLTI GILNEEIGRG CSSIRSLLTV HGMVAMAIER WGSREQKEYW LPKMARGEII GAFGLSEPNV GSDAKSVETT AVLEGEHYIL NGRKKWTTMG QIANVFLIIA LTEGKPTAFL VDKNSPGFST KPMKGLMGSR ASMIAELFMD NCLIPKDNII GSIGTGLSHI ALSSLDYGRY TIACGCVGLA QACLEESIMY CRKRKQFGAP LRQNQLIQKM ITEMVVNIKA ARLLCWSAGY MKEAGDPDSI MEVWNAKYFA SIMANKVASD AVQIHGANGC CRDYPVERYY RDAKINEIIE GTTQMHEVLI ATNAFRGM HMM: 321-388 MANKVASD AVQIHGANGC CRDYPVERYY RDAKINEIIE GTTQMHEVLI ATNAFRGM ALI: 291-355 LLCWSAGY MKEAGDPDSI MEVWNAKYFA SIMANKVASD AVQIHGANGC CRDYPVERYY RDAKINE ENV: 278-365 M ITEMVVNIKA ARLLCWSAGY MKEAGDPDSI MEVWNAKYFA SIMANKVASD AVQIHGANGC CRDYPVERYY RDAKINEIIE GTTQMHE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
No PFAM domains
Sequence: MEILSILET LEDIIEKSVS VPFSGRCLVD REEILEIIKE MRLKLPDDLK QAKWVKEERQ RILMEAQKEA NNVVKEAESK ISALVDEHEI SKQAYDQANE IISNAQKNAK EIRLGTREYA DSILNKVEEI LKEALEVVQA DRSELK HMM: 215-289 ALI: 57-131 RQ RILMEAQKEA NNVVKEAESK ISALVDEHEI SKQAYDQANE IISNAQKNAK EIRLGTREYA DSILNKVEEI LKE ENV: 47-140 LK QAKWVKEERQ RILMEAQKEA NNVVKEAESK ISALVDEHEI SKQAYDQANE IISNAQKNAK EIRLGTREYA DSILNKVEEI LKEALEVVQA DR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140
Sequence: MEKINDLRS AVKFLESQGE SILEYTKPID ANCELAMHYV NHGAGVPASP NCIEGSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLTQSPQYSK SINAIGNTAK AVFDCTVPWN MKNEFKRTFY NY
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470
PF01977: 12-424 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MEKINDLRS AVKFLESQGE SILEYTKPID ANCELAMHYV NHGAGVPASP NCIEGSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLTQSPQYSK SINAIGNTAK AVFDCTVPWN MKNEFKRTFY NY HMM: 42-442 AGVPASP NCIEGSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLTQSPQYSK SINA ALI: 53-459 GSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLTQSPQYSK SINAIGNTAK AVFDCTVPWN M ENV: 6-467 LRS AVKFLESQGE SILEYTKPID ANCELAMHYV NHGAGVPASP NCIEGSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLTQSPQYSK SINAIGNTAK AVFDCTVPWN MKNEFKRTF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470
Sequence: MEKINDLRS AVKFLESQGE SILEYTKPID ANCELAMHYV NHGAGVPASP NCIEGSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLTQSPQYSK SINAIGNTAK AVFDCTVPWN MKNEFKRTFY NY HMM: 44-429 VPASP NCIEGSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA D ALI: 54-431 SPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLT ENV: 48-466 P NCIEGSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLTQSPQYSK SINAIGNTAK AVFDCTVPWN MKNEFKRT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470
Sequence: MEKINDLRS AVKFLESQGE SILEYTKPID ANCELAMHYV NHGAGVPASP NCIEGSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLTQSPQYSK SINAIGNTAK AVFDCTVPWN MKNEFKRTFY NY HMM: 5-443 DLRS AVKFLESQGE SILEYTKPID ANCELAMHYV NHGAGVPASP NCIEGSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLTQSPQYSK SINAI ALI: 6-462 LRS AVKFLESQGE SILEYTKPID ANCELAMHYV NHGAGVPASP NCIEGSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLTQSPQYSK SINAIGNTAK AVFDCTVPWN MKNE ENV: 2-467 KINDLRS AVKFLESQGE SILEYTKPID ANCELAMHYV NHGAGVPASP NCIEGSPILY KNVKGYSIPV LMGLFGSRKR SNLLLSSQNN NSVIEVMLNA LKNRIPPKSL DNPPCQENIV RDVDIMKLLP IPTLSKYDCG PFITLGVVYA TDPETGQRNC SIHRFCIHSK DTMSIWIVPG RDLGVLYNKA IKKNASLPIS INIGLDPAIY YAACFSNPTV ATGDDELSIA GGIRGCPVNV SKCISVDALC ISNAEIVLEG EITNELVNEN LNDPLGFSLP EFLGYQGTAK SSIPLVKIKA ITHRNDAVYQ ALLGPGKEQS ELLSIPAEAS VIKLLKENLY GDFINAHYSS AGGGLLFLIL QIRKKSERDD ALVKQAGLLA LSAFHMLKHV IIVDEDVNIY SHEDVLWAMT TRFQADKDFT LIQNMPGFSA DLTQSPQYSK SINAIGNTAK AVFDCTVPWN MKNEFKRTF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470
Sequence: MNLNITDFK PGKWQNSIDV QDFIQTNYSP YDGDASFLVG SSFKTKYLWN SCKSLLVEEH LKGGILDIDT STVSGITSHK PGYIDEAYEV IKGLQTDAPL KRALVPNTGY RMTKQACQEF GVSPAPEIDN AFKNIKTHND GVFSAYSEEM RKARKSGIIT GLPDAYGRGR IIGDYRRVAL YGIDILIEEK KKDLAAISTE MSEEIIRLRQ EVSDQIASLN DLAVMGSSYG FDLRRPAANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGKDMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTDVNRLM AFGISGLSVF VDSLSAIKHS RVKVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
PF02901: 15-600 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
PF01228: 615-722 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MNLNITDFK PGKWQNSIDV QDFIQTNYSP YDGDASFLVG SSFKTKYLWN SCKSLLVEEH LKGGILDIDT STVSGITSHK PGYIDEAYEV IKGLQTDAPL KRALVPNTGY RMTKQACQEF GVSPAPEIDN AFKNIKTHND GVFSAYSEEM RKARKSGIIT GLPDAYGRGR IIGDYRRVAL YGIDILIEEK KKDLAAISTE MSEEIIRLRQ EVSDQIASLN DLAVMGSSYG FDLRRPAANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGKDMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTDVNRLM AFGISGLSVF VDSLSAIKHS RVKVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM HMM: 370-413 FKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGK ALI: 325-369 IGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE P ENV: 291-373 LIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MNLNITDFK PGKWQNSIDV QDFIQTNYSP YDGDASFLVG SSFKTKYLWN SCKSLLVEEH LKGGILDIDT STVSGITSHK PGYIDEAYEV IKGLQTDAPL KRALVPNTGY RMTKQACQEF GVSPAPEIDN AFKNIKTHND GVFSAYSEEM RKARKSGIIT GLPDAYGRGR IIGDYRRVAL YGIDILIEEK KKDLAAISTE MSEEIIRLRQ EVSDQIASLN DLAVMGSSYG FDLRRPAANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGKDMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTDVNRLM AFGISGLSVF VDSLSAIKHS RVKVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM HMM: 631-818 LALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM ALI: 548-737 P YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFH ENV: 531-740 KVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MNLNITDFK PGKWQNSIDV QDFIQTNYSP YDGDASFLVG SSFKTKYLWN SCKSLLVEEH LKGGILDIDT STVSGITSHK PGYIDEAYEV IKGLQTDAPL KRALVPNTGY RMTKQACQEF GVSPAPEIDN AFKNIKTHND GVFSAYSEEM RKARKSGIIT GLPDAYGRGR IIGDYRRVAL YGIDILIEEK KKDLAAISTE MSEEIIRLRQ EVSDQIASLN DLAVMGSSYG FDLRRPAANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGKDMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTDVNRLM AFGISGLSVF VDSLSAIKHS RVKVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM HMM: 291-423 LIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGKDMQFF GARCN ALI: 235-368 AANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE ENV: 232-376 RRPAANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MNLNITDFK PGKWQNSIDV QDFIQTNYSP YDGDASFLVG SSFKTKYLWN SCKSLLVEEH LKGGILDIDT STVSGITSHK PGYIDEAYEV IKGLQTDAPL KRALVPNTGY RMTKQACQEF GVSPAPEIDN AFKNIKTHND GVFSAYSEEM RKARKSGIIT GLPDAYGRGR IIGDYRRVAL YGIDILIEEK KKDLAAISTE MSEEIIRLRQ EVSDQIASLN DLAVMGSSYG FDLRRPAANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGKDMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTDVNRLM AFGISGLSVF VDSLSAIKHS RVKVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM HMM: 484-572 HYMHD KYAYERLMMA LHDTDVNRLM AFGISGLSVF VDSLSAIKHS RVKVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYN ALI: 414-503 DMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTD ENV: 401-511 GIACCVSA MRLGKDMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTDVNRLM AFG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MNLNITDFK PGKWQNSIDV QDFIQTNYSP YDGDASFLVG SSFKTKYLWN SCKSLLVEEH LKGGILDIDT STVSGITSHK PGYIDEAYEV IKGLQTDAPL KRALVPNTGY RMTKQACQEF GVSPAPEIDN AFKNIKTHND GVFSAYSEEM RKARKSGIIT GLPDAYGRGR IIGDYRRVAL YGIDILIEEK KKDLAAISTE MSEEIIRLRQ EVSDQIASLN DLAVMGSSYG FDLRRPAANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGKDMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTDVNRLM AFGISGLSVF VDSLSAIKHS RVKVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM HMM: 645-831 CRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM ALI: 551-738 QFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE ENV: 542-740 DFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MNLNITDFK PGKWQNSIDV QDFIQTNYSP YDGDASFLVG SSFKTKYLWN SCKSLLVEEH LKGGILDIDT STVSGITSHK PGYIDEAYEV IKGLQTDAPL KRALVPNTGY RMTKQACQEF GVSPAPEIDN AFKNIKTHND GVFSAYSEEM RKARKSGIIT GLPDAYGRGR IIGDYRRVAL YGIDILIEEK KKDLAAISTE MSEEIIRLRQ EVSDQIASLN DLAVMGSSYG FDLRRPAANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGKDMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTDVNRLM AFGISGLSVF VDSLSAIKHS RVKVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM HMM: 306-432 RTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGKDMQFF GARCNLAKLL LLSL ALI: 239-366 FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKL ENV: 233-382 RPAANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MNLNITDFK PGKWQNSIDV QDFIQTNYSP YDGDASFLVG SSFKTKYLWN SCKSLLVEEH LKGGILDIDT STVSGITSHK PGYIDEAYEV IKGLQTDAPL KRALVPNTGY RMTKQACQEF GVSPAPEIDN AFKNIKTHND GVFSAYSEEM RKARKSGIIT GLPDAYGRGR IIGDYRRVAL YGIDILIEEK KKDLAAISTE MSEEIIRLRQ EVSDQIASLN DLAVMGSSYG FDLRRPAANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGKDMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTDVNRLM AFGISGLSVF VDSLSAIKHS RVKVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM HMM: 511-591 GISGLSVF VDSLSAIKHS RVKVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLT ALI: 422-502 CNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDT ENV: 411-514 LGKDMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTDVNRLM AFGISG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MNLNITDFK PGKWQNSIDV QDFIQTNYSP YDGDASFLVG SSFKTKYLWN SCKSLLVEEH LKGGILDIDT STVSGITSHK PGYIDEAYEV IKGLQTDAPL KRALVPNTGY RMTKQACQEF GVSPAPEIDN AFKNIKTHND GVFSAYSEEM RKARKSGIIT GLPDAYGRGR IIGDYRRVAL YGIDILIEEK KKDLAAISTE MSEEIIRLRQ EVSDQIASLN DLAVMGSSYG FDLRRPAANA FEAIQWTYLA FLGAMKETNG AANSLGRLNT FFDIYIEKDI KNNILTELDA QELIDQFVIK LRLIRHLRTK SYNELFAGDP VWLTESIGGM SSDGRHMVTK TSYRFLQTLN NLGAAPEPNL TILWSTKLPE PFKQFCSKMS IKTSAIQYEN DDLMQPLYGD DYGIACCVSA MRLGKDMQFF GARCNLAKLL LLSLNGGKDE ISGTQVAPEI EPYEGEYLEY DKVMSNFLKM QDWLTGLYVN TMNVIHYMHD KYAYERLMMA LHDTDVNRLM AFGISGLSVF VDSLSAIKHS RVKVIRDERG IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM HMM: 662-847 KDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM ALI: 550-737 PQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFH ENV: 538-741 G IITDFETELP YPQFGNNDDR VDSIAKEVVE SFYNSLKSHP TYRNATHTLS VLTITSNVVY GKKTGATPDG RKKGEPFAPG ANPMHNRDKS GILALLSSVA KIPYNSCRDG ISLTASIIPA ALGKDEDTKI RNLAAIIDGY MMSSGHHINV NVLDKATLEN AMAEPLKYSS LTVRVSGYAV HFIKLTREQQ LEVISRTFHE AM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDKYVCSVC GYVYDPAEGD PDGGIAPGTA FEDIPEDWVC PVCGVGKDSF EKQ
10 20 30 40 50
PF00301: 2-49 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MDKYVCSVC GYVYDPAEGD PDGGIAPGTA FEDIPEDWVC PVCGVGKDSF EKQ HMM: 425-469 ALI: 3-47 YVCSVC GYVYDPAEGD PDGGIAPGTA FEDIPEDWVC PVCGVGKDS ENV: 1-52 DKYVCSVC GYVYDPAEGD PDGGIAPGTA FEDIPEDWVC PVCGVGKDSF EKQ Position: 10 20 30 40 50
Sequence: MDDNYKHPV DEKKVKFKAN IVGSKKETRV WTLLIIVVTF FISIFMSFFS NKTIGNASTA VSFLIVFIII IISILFDVVG TAATAADEAP FHSMASRKLY GARQAIRLIR NADKVSNFCN DVVGDICGVV SGAAVALIVY RFSGNATNSQ NSIFALSFTA LVASLTVGGK SLGKSIALSN SNYIIYKVAI ITNFPFGKFK ILKKLNFRSK RKKQNKKTKS QKDKGN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220
Sequence: MDDNYKHPV DEKKVKFKAN IVGSKKETRV WTLLIIVVTF FISIFMSFFS NKTIGNASTA VSFLIVFIII IISILFDVVG TAATAADEAP FHSMASRKLY GARQAIRLIR NADKVSNFCN DVVGDICGVV SGAAVALIVY RFSGNATNSQ NSIFALSFTA LVASLTVGGK SLGKSIALSN SNYIIYKVAI ITNFPFGKFK ILKKLNFRSK RKKQNKKTKS QKDKGN HMM: 17-91 AN IVGSKKETRV WTLLIIVVTF FISIFMSFFS NKTIGNASTA VSFLIVFIII IISILFDVVG TAATAADEAP FHS ALI: 27-101 RV WTLLIIVVTF FISIFMSFFS NKTIGNASTA VSFLIVFIII IISILFDVVG TAATAADEAP FHSMASRKLY GAR ENV: 12-148 KVKFKAN IVGSKKETRV WTLLIIVVTF FISIFMSFFS NKTIGNASTA VSFLIVFIII IISILFDVVG TAATAADEAP FHSMASRKLY GARQAIRLIR NADKVSNFCN DVVGDICGVV SGAAVALIVY RFSGNATNSQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220
No PFAM domains
Sequence: MIVVNYVII GNSAAAIGCV SGIRTIDKES PITLISDEPH FTYSRPLISY WLKGKVDDEK MYYRNSDFYE KNNCNVILGK KVIKIESDSK LVVLEDDSNI KYDKLLVATG SSPFVPPVEG LNEAKNTFTF MKWDSVKDVK SAVKTDSKVV IMGAGLIGLK AAEGLHEICE DITVVDMADR ILPSILDKKG ADFVQRHIEK HNIKFILNDA AQSVYNNSIT LKSGQTIDYD VLIIAVGVRP NTELVKNAGG NVNRGIVTDK KQETSLKDIY AAGDCTESFD ICSEQNKILA LLPNAYMQGE IAGINMAGGD KVFDTAMPMN AIGFFGLHML TAGSMEGECV EVIDENNYKK MFFADNLLKG YILIGEINRA GIYTSLIREK IHLQELDINL LKNSPQLLVF NKNTRKAKLG HMM: 7-33 II GNSAAAIGCV SGIRTIDKES PITLI ALI: 147-173 VV IMGAGLIGLK AAEGLHEICE DITVV ENV: 142-181 KTDSKVV IMGAGLIGLK AAEGLHEICE DITVVDMADR ILP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400
Sequence: MIVVNYVII GNSAAAIGCV SGIRTIDKES PITLISDEPH FTYSRPLISY WLKGKVDDEK MYYRNSDFYE KNNCNVILGK KVIKIESDSK LVVLEDDSNI KYDKLLVATG SSPFVPPVEG LNEAKNTFTF MKWDSVKDVK SAVKTDSKVV IMGAGLIGLK AAEGLHEICE DITVVDMADR ILPSILDKKG ADFVQRHIEK HNIKFILNDA AQSVYNNSIT LKSGQTIDYD VLIIAVGVRP NTELVKNAGG NVNRGIVTDK KQETSLKDIY AAGDCTESFD ICSEQNKILA LLPNAYMQGE IAGINMAGGD KVFDTAMPMN AIGFFGLHML TAGSMEGECV EVIDENNYKK MFFADNLLKG YILIGEINRA GIYTSLIREK IHLQELDINL LKNSPQLLVF NKNTRKAKLG HMM: 313-345 TAMPMN AIGFFGLHML TAGSMEGECV EVIDENN ALI: 205-237 LNDA AQSVYNNSIT LKSGQTIDYD VLIIAVGVR ENV: 190-263 DFVQRHIEK HNIKFILNDA AQSVYNNSIT LKSGQTIDYD VLIIAVGVRP NTELVKNAGG NVNRGIVTDK KQETS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400
Sequence: MKILNYDVA IIGCGISGIF AGYELTKLNP QLKVLMIEQG NTIFDRNCPI VANKIKDCVR CKSCDIMRGF GGAGAFSDGK FNFTTAFGGW LNDYLDDADV MKLINYVDSV NVEFGATKEK YSTYTDAAKI IEKKAIENDL HLLQAAVKHL GTENNVEILK GMYNHLTKLL EIKCNTQVIN IMPSQDGYQL DLYNGESINC NYLIAAPGRS GAEWFSKQCK QLKLNLINNQ VDIGVRVELP AKVFEHITDV VYESKLIYRT KQYGDLVRTF CMNPYGHVVS ENVDDIITVN GHSYTDPQLR SENTNFALLV SNRFTQPFNE PYQYGKRIAS LSNMLGGGVL VQRFGDLIKG NRTNAHRLSQ SFTHPTLNAT PGDLSLVLTK RHLDNIIEMI YALDKIAPGT ANYDTLLYGV EVKFYSSRLE LTNELETQLP NMFAIGDGAG VTRGLSQASA SGVHVARTIA NRISKKPLPK LKNRY
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470
Sequence: MKILNYDVA IIGCGISGIF AGYELTKLNP QLKVLMIEQG NTIFDRNCPI VANKIKDCVR CKSCDIMRGF GGAGAFSDGK FNFTTAFGGW LNDYLDDADV MKLINYVDSV NVEFGATKEK YSTYTDAAKI IEKKAIENDL HLLQAAVKHL GTENNVEILK GMYNHLTKLL EIKCNTQVIN IMPSQDGYQL DLYNGESINC NYLIAAPGRS GAEWFSKQCK QLKLNLINNQ VDIGVRVELP AKVFEHITDV VYESKLIYRT KQYGDLVRTF CMNPYGHVVS ENVDDIITVN GHSYTDPQLR SENTNFALLV SNRFTQPFNE PYQYGKRIAS LSNMLGGGVL VQRFGDLIKG NRTNAHRLSQ SFTHPTLNAT PGDLSLVLTK RHLDNIIEMI YALDKIAPGT ANYDTLLYGV EVKFYSSRLE LTNELETQLP NMFAIGDGAG VTRGLSQASA SGVHVARTIA NRISKKPLPK LKNRY HMM: 2-41 ILNYDVA IIGCGISGIF AGYELTKLNP QLKVLMIEQG NTI ALI: 2-41 ILNYDVA IIGCGISGIF AGYELTKLNP QLKVLMIEQG NTI ENV: 1-44 KILNYDVA IIGCGISGIF AGYELTKLNP QLKVLMIEQG NTIFDR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470
Sequence: MKILNYDVA IIGCGISGIF AGYELTKLNP QLKVLMIEQG NTIFDRNCPI VANKIKDCVR CKSCDIMRGF GGAGAFSDGK FNFTTAFGGW LNDYLDDADV MKLINYVDSV NVEFGATKEK YSTYTDAAKI IEKKAIENDL HLLQAAVKHL GTENNVEILK GMYNHLTKLL EIKCNTQVIN IMPSQDGYQL DLYNGESINC NYLIAAPGRS GAEWFSKQCK QLKLNLINNQ VDIGVRVELP AKVFEHITDV VYESKLIYRT KQYGDLVRTF CMNPYGHVVS ENVDDIITVN GHSYTDPQLR SENTNFALLV SNRFTQPFNE PYQYGKRIAS LSNMLGGGVL VQRFGDLIKG NRTNAHRLSQ SFTHPTLNAT PGDLSLVLTK RHLDNIIEMI YALDKIAPGT ANYDTLLYGV EVKFYSSRLE LTNELETQLP NMFAIGDGAG VTRGLSQASA SGVHVARTIA NRISKKPLPK LKNRY HMM: 265-289 VRTF CMNPYGHVVS ENVDDIITVN G ALI: 140-164 LLQAAVKHL GTENNVEILK GMYNHL ENV: 129-174 IEKKAIENDL HLLQAAVKHL GTENNVEILK GMYNHLTKLL EIKCNT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470
Sequence: MGRKILIIG GVAGGASAAA RLRRNSEEDQ IIMFERGPHV SFSNCSLPYH LSGVVKEIDD LVLMNPERFL KQYNIDARIN SEVTAIDRKN KTVTVKRIDL GEEYTETYDK LILSPGASPI VPSLPGIENV NVFTVRNVVN IDELNQFVKQ MNTKDITVIG GGYVGVEVAE NLNEAGYNVS LIEATNQILR PFDYDMVQIF HKVLIDHNVN LIVGDKVERF EKDKVVLASG KTINAGAVVM AIGVSPETYL AKEAGLEIGE TGAIKVDKNY LTNDPDIYAI GDAIEVYHAL THTMTKLSLA GPALKQARIV ADHINNKRTS NHGYIGSSAI KVFEYNGAST GLNESLIKAL NMKINYDIVR IILSDKVGIM PNAAPMHFKL LFEVPTGKIL GAQAIGKGDV TKRIDVVAAA IKFGGTVEDL KDLEFSYAPP FTTAKDIVNY AGYVGSNLLN GDFKQVNVDK VRELVENNNI IIDVREINEF KRGHIKGAIN IPLSELRERI DEIPKDRPVY LHCRTGQRSY NAALALQNMG FNNVINITGS FLGVSFYEYY NDKFYDRESI VTEYNFI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560
PF07992: 3-292 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
PF02852: 327-431 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
PF00581: 457-540 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MGRKILIIG GVAGGASAAA RLRRNSEEDQ IIMFERGPHV SFSNCSLPYH LSGVVKEIDD LVLMNPERFL KQYNIDARIN SEVTAIDRKN KTVTVKRIDL GEEYTETYDK LILSPGASPI VPSLPGIENV NVFTVRNVVN IDELNQFVKQ MNTKDITVIG GGYVGVEVAE NLNEAGYNVS LIEATNQILR PFDYDMVQIF HKVLIDHNVN LIVGDKVERF EKDKVVLASG KTINAGAVVM AIGVSPETYL AKEAGLEIGE TGAIKVDKNY LTNDPDIYAI GDAIEVYHAL THTMTKLSLA GPALKQARIV ADHINNKRTS NHGYIGSSAI KVFEYNGAST GLNESLIKAL NMKINYDIVR IILSDKVGIM PNAAPMHFKL LFEVPTGKIL GAQAIGKGDV TKRIDVVAAA IKFGGTVEDL KDLEFSYAPP FTTAKDIVNY AGYVGSNLLN GDFKQVNVDK VRELVENNNI IIDVREINEF KRGHIKGAIN IPLSELRERI DEIPKDRPVY LHCRTGQRSY NAALALQNMG FNNVINITGS FLGVSFYEYY NDKFYDRESI VTEYNFI HMM: 8-39 G GVAGGASAAA RLRRNSEEDQ IIMFERGPHV S ALI: 5-36 LIIG GVAGGASAAA RLRRNSEEDQ IIMFERGP ENV: 3-42 KILIIG GVAGGASAAA RLRRNSEEDQ IIMFERGPHV SFSN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560
Sequence: MGRKILIIG GVAGGASAAA RLRRNSEEDQ IIMFERGPHV SFSNCSLPYH LSGVVKEIDD LVLMNPERFL KQYNIDARIN SEVTAIDRKN KTVTVKRIDL GEEYTETYDK LILSPGASPI VPSLPGIENV NVFTVRNVVN IDELNQFVKQ MNTKDITVIG GGYVGVEVAE NLNEAGYNVS LIEATNQILR PFDYDMVQIF HKVLIDHNVN LIVGDKVERF EKDKVVLASG KTINAGAVVM AIGVSPETYL AKEAGLEIGE TGAIKVDKNY LTNDPDIYAI GDAIEVYHAL THTMTKLSLA GPALKQARIV ADHINNKRTS NHGYIGSSAI KVFEYNGAST GLNESLIKAL NMKINYDIVR IILSDKVGIM PNAAPMHFKL LFEVPTGKIL GAQAIGKGDV TKRIDVVAAA IKFGGTVEDL KDLEFSYAPP FTTAKDIVNY AGYVGSNLLN GDFKQVNVDK VRELVENNNI IIDVREINEF KRGHIKGAIN IPLSELRERI DEIPKDRPVY LHCRTGQRSY NAALALQNMG FNNVINITGS FLGVSFYEYY NDKFYDRESI VTEYNFI HMM: 5-30 LIIG GVAGGASAAA RLRRNSEEDQ II ALI: 152-177 KDITVIG GGYVGVEVAE NLNEAGYNV ENV: 132-187 TVRNVVN IDELNQFVKQ MNTKDITVIG GGYVGVEVAE NLNEAGYNVS LIEATNQIL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560
Sequence: MGRKILIIG GVAGGASAAA RLRRNSEEDQ IIMFERGPHV SFSNCSLPYH LSGVVKEIDD LVLMNPERFL KQYNIDARIN SEVTAIDRKN KTVTVKRIDL GEEYTETYDK LILSPGASPI VPSLPGIENV NVFTVRNVVN IDELNQFVKQ MNTKDITVIG GGYVGVEVAE NLNEAGYNVS LIEATNQILR PFDYDMVQIF HKVLIDHNVN LIVGDKVERF EKDKVVLASG KTINAGAVVM AIGVSPETYL AKEAGLEIGE TGAIKVDKNY LTNDPDIYAI GDAIEVYHAL THTMTKLSLA GPALKQARIV ADHINNKRTS NHGYIGSSAI KVFEYNGAST GLNESLIKAL NMKINYDIVR IILSDKVGIM PNAAPMHFKL LFEVPTGKIL GAQAIGKGDV TKRIDVVAAA IKFGGTVEDL KDLEFSYAPP FTTAKDIVNY AGYVGSNLLN GDFKQVNVDK VRELVENNNI IIDVREINEF KRGHIKGAIN IPLSELRERI DEIPKDRPVY LHCRTGQRSY NAALALQNMG FNNVINITGS FLGVSFYEYY NDKFYDRESI VTEYNFI HMM: 309-345 ADHINNKRTS NHGYIGSSAI KVFEYNGAST GLNESLI ALI: 207-243 VN LIVGDKVERF EKDKVVLASG KTINAGAVVM AIGVS ENV: 194-260 MVQIF HKVLIDHNVN LIVGDKVERF EKDKVVLASG KTINAGAVVM AIGVSPETYL AKEAGLEIGE TG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560
Sequence: MEVVNFVNG KTELYGILGD PIEHTKSPFI HNTLFKQFNI NAIYIPIHVN EVCLENVING LKAQNISGFN VTVPHKKSII KYLDDISHDA LLMGAVNTVK NIQGRLKGYN TDAEGFVRDF KEGLDTNFKD KRVMILGAGG TARALAVKLA SEGIEHLTLV NRTEENAKNI TELIKNNYGG IASYMLPDST KLFDQMSQSH IIINTTPAGM STYLDSTPFN IDYVFDKNQV VYDVVYSPEK TKFLLQAESY GCKTRNGFGM LINQGVSAFE IWTGNIVPRQ MAIELLNKII KMKDFPK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290
PF08501: 15-98 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF01488: 125-205 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF18317: 255-279 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MEVVNFVNG KTELYGILGD PIEHTKSPFI HNTLFKQFNI NAIYIPIHVN EVCLENVING LKAQNISGFN VTVPHKKSII KYLDDISHDA LLMGAVNTVK NIQGRLKGYN TDAEGFVRDF KEGLDTNFKD KRVMILGAGG TARALAVKLA SEGIEHLTLV NRTEENAKNI TELIKNNYGG IASYMLPDST KLFDQMSQSH IIINTTPAGM STYLDSTPFN IDYVFDKNQV VYDVVYSPEK TKFLLQAESY GCKTRNGFGM LINQGVSAFE IWTGNIVPRQ MAIELLNKII KMKDFPK HMM: 172-210 IKNNYGG IASYMLPDST KLFDQMSQSH IIINTTPAGM ST ALI: 125-163 NFKD KRVMILGAGG TARALAVKLA SEGIEHLTLV NRTEE ENV: 108-184 N TDAEGFVRDF KEGLDTNFKD KRVMILGAGG TARALAVKLA SEGIEHLTLV NRTEENAKNI TELIKNNYGG IASYML Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290
Sequence: MSSINNVSS NTLRLSGLVS GMDTDTVVKQ MLAAERAKID KIEAKVQIGE WQTEAYREIT ASLQSFYSTY FDTTSPLNLK STNSFASFAT SYSNAASTNY VTLTGVSGAQ AGKYSITELK TATSATLTGG NVSKDIESGT INLSDLTNMI GDNKIFITVN GMSNFISIPT DGSITSVNDL KEALQQEINN AFGADKINVE LNSTADGIKF SAVRPTDTFS ISTDSPALSV LGLDSSNLSN KIDLSAKVTD LTNSLGTTLT TGANNTIAFT INGISFTFDL SQKSIKDIMN EVNTNTKLNV TMKYDVTKNS FSIKSNGTGA MEKVEITDSI GNFMSALGIT GSSAGTDASV TFSDGTKIVR SSNSFTYDGI TYNIKQDFTA GTDAITGKVT EPIEATITAD ATKTFEYLKG FVDKYNELIE KINNKLTEEK YRNYSPLTEE QKSQMTKEQI EKWEEKAKSG LLKNDSILTG ILADLRNVLY SSVEGAGISL SSIGITTSSD YKKNGKLEIN EEKLKDAIIN KSEEIKTLFT KSSEITYYES LDSQSAKSQR YKESGLAQRI SDIIQNAIRT STDKNGYKGT LLEKAGISGD RSEFTNSLFK EMMGFQEMID EMNSRLNYKE DALYAKFTAM ESALSKLNEQ QNYLLSMLGN GK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
PF02465: 18-123 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF07195: 343-638 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MSSINNVSS NTLRLSGLVS GMDTDTVVKQ MLAAERAKID KIEAKVQIGE WQTEAYREIT ASLQSFYSTY FDTTSPLNLK STNSFASFAT SYSNAASTNY VTLTGVSGAQ AGKYSITELK TATSATLTGG NVSKDIESGT INLSDLTNMI GDNKIFITVN GMSNFISIPT DGSITSVNDL KEALQQEINN AFGADKINVE LNSTADGIKF SAVRPTDTFS ISTDSPALSV LGLDSSNLSN KIDLSAKVTD LTNSLGTTLT TGANNTIAFT INGISFTFDL SQKSIKDIMN EVNTNTKLNV TMKYDVTKNS FSIKSNGTGA MEKVEITDSI GNFMSALGIT GSSAGTDASV TFSDGTKIVR SSNSFTYDGI TYNIKQDFTA GTDAITGKVT EPIEATITAD ATKTFEYLKG FVDKYNELIE KINNKLTEEK YRNYSPLTEE QKSQMTKEQI EKWEEKAKSG LLKNDSILTG ILADLRNVLY SSVEGAGISL SSIGITTSSD YKKNGKLEIN EEKLKDAIIN KSEEIKTLFT KSSEITYYES LDSQSAKSQR YKESGLAQRI SDIIQNAIRT STDKNGYKGT LLEKAGISGD RSEFTNSLFK EMMGFQEMID EMNSRLNYKE DALYAKFTAM ESALSKLNEQ QNYLLSMLGN GK HMM: 158-216 N GMSNFISIPT DGSITSVNDL KEALQQEINN AFGADKINVE LNSTADGIKF SAVRPTDT ALI: 240-298 IDLSAKVTD LTNSLGTTLT TGANNTIAFT INGISFTFDL SQKSIKDIMN EVNTNTKLNV ENV: 233-325 SSNLSN KIDLSAKVTD LTNSLGTTLT TGANNTIAFT INGISFTFDL SQKSIKDIMN EVNTNTKLNV TMKYDVTKNS FSIKSNGTGA MEKVEIT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MSSINNVSS NTLRLSGLVS GMDTDTVVKQ MLAAERAKID KIEAKVQIGE WQTEAYREIT ASLQSFYSTY FDTTSPLNLK STNSFASFAT SYSNAASTNY VTLTGVSGAQ AGKYSITELK TATSATLTGG NVSKDIESGT INLSDLTNMI GDNKIFITVN GMSNFISIPT DGSITSVNDL KEALQQEINN AFGADKINVE LNSTADGIKF SAVRPTDTFS ISTDSPALSV LGLDSSNLSN KIDLSAKVTD LTNSLGTTLT TGANNTIAFT INGISFTFDL SQKSIKDIMN EVNTNTKLNV TMKYDVTKNS FSIKSNGTGA MEKVEITDSI GNFMSALGIT GSSAGTDASV TFSDGTKIVR SSNSFTYDGI TYNIKQDFTA GTDAITGKVT EPIEATITAD ATKTFEYLKG FVDKYNELIE KINNKLTEEK YRNYSPLTEE QKSQMTKEQI EKWEEKAKSG LLKNDSILTG ILADLRNVLY SSVEGAGISL SSIGITTSSD YKKNGKLEIN EEKLKDAIIN KSEEIKTLFT KSSEITYYES LDSQSAKSQR YKESGLAQRI SDIIQNAIRT STDKNGYKGT LLEKAGISGD RSEFTNSLFK EMMGFQEMID EMNSRLNYKE DALYAKFTAM ESALSKLNEQ QNYLLSMLGN GK HMM: 169-240 DGSITSVNDL KEALQQEINN AFGADKINVE LNSTADGIKF SAVRPTDTFS ISTDSPALSV LGLDSSNLSN KI ALI: 381-453 DAITGKVT EPIEATITAD ATKTFEYLKG FVDKYNELIE KINNKLTEEK YRNYSPLTEE QKSQMTKEQI EKWEE ENV: 356-461 IVR SSNSFTYDGI TYNIKQDFTA GTDAITGKVT EPIEATITAD ATKTFEYLKG FVDKYNELIE KINNKLTEEK YRNYSPLTEE QKSQMTKEQI EKWEEKAKSG LLK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MSSINNVSS NTLRLSGLVS GMDTDTVVKQ MLAAERAKID KIEAKVQIGE WQTEAYREIT ASLQSFYSTY FDTTSPLNLK STNSFASFAT SYSNAASTNY VTLTGVSGAQ AGKYSITELK TATSATLTGG NVSKDIESGT INLSDLTNMI GDNKIFITVN GMSNFISIPT DGSITSVNDL KEALQQEINN AFGADKINVE LNSTADGIKF SAVRPTDTFS ISTDSPALSV LGLDSSNLSN KIDLSAKVTD LTNSLGTTLT TGANNTIAFT INGISFTFDL SQKSIKDIMN EVNTNTKLNV TMKYDVTKNS FSIKSNGTGA MEKVEITDSI GNFMSALGIT GSSAGTDASV TFSDGTKIVR SSNSFTYDGI TYNIKQDFTA GTDAITGKVT EPIEATITAD ATKTFEYLKG FVDKYNELIE KINNKLTEEK YRNYSPLTEE QKSQMTKEQI EKWEEKAKSG LLKNDSILTG ILADLRNVLY SSVEGAGISL SSIGITTSSD YKKNGKLEIN EEKLKDAIIN KSEEIKTLFT KSSEITYYES LDSQSAKSQR YKESGLAQRI SDIIQNAIRT STDKNGYKGT LLEKAGISGD RSEFTNSLFK EMMGFQEMID EMNSRLNYKE DALYAKFTAM ESALSKLNEQ QNYLLSMLGN GK HMM: 178-232 L KEALQQEINN AFGADKINVE LNSTADGIKF SAVRPTDTFS ISTDSPALSV LGLD ALI: 577-635 GT LLEKAGISGD RSEFTNSLFK EMMGFQEMID EMNSRLNYKE DALYAKFTAM ESALSKL ENV: 495-646 TSSD YKKNGKLEIN EEKLKDAIIN KSEEIKTLFT KSSEITYYES LDSQSAKSQR YKESGLAQRI SDIIQNAIRT STDKNGYKGT LLEKAGISGD RSEFTNSLFK EMMGFQEMID EMNSRLNYKE DALYAKFTAM ESALSKLNEQ QNYLLSML Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MYLFNDFQN EIKESIDDFI LNVIEKQNSN DINKKTFLYE VLEQLGSLGY KGLMVSEEFG GVGLDAVSAL LIISRIAYSD PSLAHVLETI NFGFCYPIYL LGTQEQKELF LSNTLRENYI GTLAVNEPEK EIKTIAHKDG DYYILNGIKN MITCAGTAQY ALVNALVDNN NTFFIVDLKN TDGIVIGKTE ETMGLESMAV SEIYLEDAKV HKDNILLGIG KGLEVILKSM ELMRICNSAV ALGIAQRAFN EAVEYSKVRI INGQPLFEMQ SVKYDLAEIK ANLEMMETLV YYTGNIYSEN VEGKILHSSI SKLIVTEKAK EICDKCLQYF GGYGYVKGVK VEKLYRDIRI MTILGGVSEV MKWSISRFI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
PF02771: 6-115 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF02770: 129-206 ♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 218-366 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
Sequence: MYLFNDFQN EIKESIDDFI LNVIEKQNSN DINKKTFLYE VLEQLGSLGY KGLMVSEEFG GVGLDAVSAL LIISRIAYSD PSLAHVLETI NFGFCYPIYL LGTQEQKELF LSNTLRENYI GTLAVNEPEK EIKTIAHKDG DYYILNGIKN MITCAGTAQY ALVNALVDNN NTFFIVDLKN TDGIVIGKTE ETMGLESMAV SEIYLEDAKV HKDNILLGIG KGLEVILKSM ELMRICNSAV ALGIAQRAFN EAVEYSKVRI INGQPLFEMQ SVKYDLAEIK ANLEMMETLV YYTGNIYSEN VEGKILHSSI SKLIVTEKAK EICDKCLQYF GGYGYVKGVK VEKLYRDIRI MTILGGVSEV MKWSISRFI HMM: 51-280 LMVSEEFG GVGLDAVSAL LIISRIAYSD PSLAHVLETI NFGFCYPIYL LGTQEQKELF LSNTLRENYI GTLAVNEPEK EIKTIAHKDG DYYILNGIKN MITCAGTAQY ALVNALVDNN NTFFIVDLKN TDGIVIGKTE ETMGLESMAV SEIYLEDAKV HKDNILLGIG KGLEVILKSM ELMRICNSAV ALGIAQRAFN EAVEYSKVRI INGQPLFEMQ SVKYDLAEIK AN ALI: 43-258 LGSLGY KGLMVSEEFG GVGLDAVSAL LIISRIAYSD PSLAHVLETI NFGFCYPIYL LGTQEQKELF LSNTLRENYI GTLAVNEPEK EIKTIAHKDG DYYILNGIKN MITCAGTAQY ALVNALVDNN NTFFIVDLKN TDGIVIGKTE ETMGLESMAV SEIYLEDAKV HKDNILLGIG KGLEVILKSM ELMRICNSAV ALGIAQRAFN EAVEYSKVRI ENV: 36-279 LYE VLEQLGSLGY KGLMVSEEFG GVGLDAVSAL LIISRIAYSD PSLAHVLETI NFGFCYPIYL LGTQEQKELF LSNTLRENYI GTLAVNEPEK EIKTIAHKDG DYYILNGIKN MITCAGTAQY ALVNALVDNN NTFFIVDLKN TDGIVIGKTE ETMGLESMAV SEIYLEDAKV HKDNILLGIG KGLEVILKSM ELMRICNSAV ALGIAQRAFN EAVEYSKVRI INGQPLFEMQ SVKYDLAEIK A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MYLFNDFQN EIKESIDDFI LNVIEKQNSN DINKKTFLYE VLEQLGSLGY KGLMVSEEFG GVGLDAVSAL LIISRIAYSD PSLAHVLETI NFGFCYPIYL LGTQEQKELF LSNTLRENYI GTLAVNEPEK EIKTIAHKDG DYYILNGIKN MITCAGTAQY ALVNALVDNN NTFFIVDLKN TDGIVIGKTE ETMGLESMAV SEIYLEDAKV HKDNILLGIG KGLEVILKSM ELMRICNSAV ALGIAQRAFN EAVEYSKVRI INGQPLFEMQ SVKYDLAEIK ANLEMMETLV YYTGNIYSEN VEGKILHSSI SKLIVTEKAK EICDKCLQYF GGYGYVKGVK VEKLYRDIRI MTILGGVSEV MKWSISRFI HMM: 327-395 YF GGYGYVKGVK VEKLYRDIRI MTILGGVSEV MKWSISRFI ALI: 290-357 YTGNIYSEN VEGKILHSSI SKLIVTEKAK EICDKCLQYF GGYGYVKGVK VEKLYRDIRI MTILGGVSE ENV: 259-362 INGQPLFEMQ SVKYDLAEIK ANLEMMETLV YYTGNIYSEN VEGKILHSSI SKLIVTEKAK EICDKCLQYF GGYGYVKGVK VEKLYRDIRI MTILGGVSEV MKWS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MSHILTEEN IQKLREELDY RMNVKRNEIA REKLIAAEHG DRSENAEYKE ACERFNANDD RIQQLMTIIS TATVIDDKNT DKTKLGINTK ARIKFIEDNE EDIITLVTTM DADVKKMHIS IEADLGKALY GKKVGDLVEV NAPSGKYFVE VLEIL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150
PF03449: 3-73 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF01272: 81-153 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
Sequence: MSHILTEEN IQKLREELDY RMNVKRNEIA REKLIAAEHG DRSENAEYKE ACERFNANDD RIQQLMTIIS TATVIDDKNT DKTKLGINTK ARIKFIEDNE EDIITLVTTM DADVKKMHIS IEADLGKALY GKKVGDLVEV NAPSGKYFVE VLEIL HMM: 42-96 ENAEYKE ACERFNANDD RIQQLMTIIS TATVIDDKNT DKTKLGINTK ARIKFIED ALI: 6-65 EEN IQKLREELDY RMNVKRNEIA REKLIAAEHG DRSENAEYKE ACERFNANDD RIQQLMT ENV: 1-73 SHILTEEN IQKLREELDY RMNVKRNEIA REKLIAAEHG DRSENAEYKE ACERFNANDD RIQQLMTIIS TATVI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150
Sequence: MKYVCNICG YIYDPAEGAP DSGVPAGTEW EAVPDDFVCP LCGVGKDDFS PAE
10 20 30 40 50
PF00301: 1-48 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
Sequence: MKYVCNICG YIYDPAEGAP DSGVPAGTEW EAVPDDFVCP LCGVGKDDFS PAE HMM: 425-469 ALI: 2-46 YVCNICG YIYDPAEGAP DSGVPAGTEW EAVPDDFVCP LCGVGKDD ENV: 1-52 KYVCNICG YIYDPAEGAP DSGVPAGTEW EAVPDDFVCP LCGVGKDDFS PAE Position: 10 20 30 40 50
Sequence: MTRTIISII LFVISALLAK CSIRHFLGRG YLLNNAYIFA PKTERESMNK KPYYRQSAVV FLLMSAVFIV LGLAVLFEDT KLELIELPLI AGAVIYAVIS EVKIEKKSK
10 20 30 40 50 60 70 80 90 100
PF12650: 8-100 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
Sequence: MTRTIISII LFVISALLAK CSIRHFLGRG YLLNNAYIFA PKTERESMNK KPYYRQSAVV FLLMSAVFIV LGLAVLFEDT KLELIELPLI AGAVIYAVIS EVKIEKKSK HMM: 76-121 EDT KLELIELPLI AGAVIYAVIS EVKIEKKSK ALI: 40-86 KTERESMNK KPYYRQSAVV FLLMSAVFIV LGLAVLFEDT KLELIELP ENV: 30-104 LLNNAYIFA PKTERESMNK KPYYRQSAVV FLLMSAVFIV LGLAVLFEDT KLELIELPLI AGAVIYAVIS EVKIEK Position: 10 20 30 40 50 60 70 80 90 100
Sequence: MAFNIITEA RRCLNCKNPG CKKGCPISTP IPDVIRTFLD GDIDKAGGML FENNPLSVIC SLICNHDNQC EGNCVLGRKG SPVHFSDIEN YISDTYFDKL QFGEIKKNNI HVGVIGGGPA GITIAILLAQ RGYNITLFES REKIGGVLRY GIPEFRLPKQ LLERYKKLMI SLGIKIRPNT SIGTTITIDD LFRDGYKAIF IGTGVWKPNT LHIKGESLGN VHFAINYLTN PDVYTLGETL NVIGAGNSAM DVARTALRHG CKKVTVFSRS EKLAASVTEV EYAKFDGVDF VMGVEPVEIT DNGTIFVSVE KDEEGNRKRI EGSEKLYPAD STIIAVSQGP RDRIVSTTTG LDVTDRGLLV TNTYGKTTRD GIFAAGDVVR GARTVVEAVN YSKQVADTMD EYLRSL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400
PF14691: 4-96 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF07992: 110-388 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MAFNIITEA RRCLNCKNPG CKKGCPISTP IPDVIRTFLD GDIDKAGGML FENNPLSVIC SLICNHDNQC EGNCVLGRKG SPVHFSDIEN YISDTYFDKL QFGEIKKNNI HVGVIGGGPA GITIAILLAQ RGYNITLFES REKIGGVLRY GIPEFRLPKQ LLERYKKLMI SLGIKIRPNT SIGTTITIDD LFRDGYKAIF IGTGVWKPNT LHIKGESLGN VHFAINYLTN PDVYTLGETL NVIGAGNSAM DVARTALRHG CKKVTVFSRS EKLAASVTEV EYAKFDGVDF VMGVEPVEIT DNGTIFVSVE KDEEGNRKRI EGSEKLYPAD STIIAVSQGP RDRIVSTTTG LDVTDRGLLV TNTYGKTTRD GIFAAGDVVR GARTVVEAVN YSKQVADTMD EYLRSL HMM: 2-71 FNIITEA RRCLNCKNPG CKKGCPISTP IPDVIRTFLD GDIDKAGGML FENNPLSVIC SLICNHDNQC EGN ALI: 105-179 KNNI HVGVIGGGPA GITIAILLAQ RGYNITLFES REKIGGVLRY GIPEFRLPKQ LLERYKKLMI SLGIKIRPNT S ENV: 74-188 LGRKG SPVHFSDIEN YISDTYFDKL QFGEIKKNNI HVGVIGGGPA GITIAILLAQ RGYNITLFES REKIGGVLRY GIPEFRLPKQ LLERYKKLMI SLGIKIRPNT SIGTTITIDD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400
Sequence: MAFNIITEA RRCLNCKNPG CKKGCPISTP IPDVIRTFLD GDIDKAGGML FENNPLSVIC SLICNHDNQC EGNCVLGRKG SPVHFSDIEN YISDTYFDKL QFGEIKKNNI HVGVIGGGPA GITIAILLAQ RGYNITLFES REKIGGVLRY GIPEFRLPKQ LLERYKKLMI SLGIKIRPNT SIGTTITIDD LFRDGYKAIF IGTGVWKPNT LHIKGESLGN VHFAINYLTN PDVYTLGETL NVIGAGNSAM DVARTALRHG CKKVTVFSRS EKLAASVTEV EYAKFDGVDF VMGVEPVEIT DNGTIFVSVE KDEEGNRKRI EGSEKLYPAD STIIAVSQGP RDRIVSTTTG LDVTDRGLLV TNTYGKTTRD GIFAAGDVVR GARTVVEAVN YSKQVADTMD EYLRSL HMM: 176-221 PNT SIGTTITIDD LFRDGYKAIF IGTGVWKPNT LHIKGESLGN VHF ALI: 234-280 LGETL NVIGAGNSAM DVARTALRHG CKKVTVFSRS EKLAASVTEV EY ENV: 205-285 KPNT LHIKGESLGN VHFAINYLTN PDVYTLGETL NVIGAGNSAM DVARTALRHG CKKVTVFSRS EKLAASVTEV EYAKFDG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400
Sequence: MAFNIITEA RRCLNCKNPG CKKGCPISTP IPDVIRTFLD GDIDKAGGML FENNPLSVIC SLICNHDNQC EGNCVLGRKG SPVHFSDIEN YISDTYFDKL QFGEIKKNNI HVGVIGGGPA GITIAILLAQ RGYNITLFES REKIGGVLRY GIPEFRLPKQ LLERYKKLMI SLGIKIRPNT SIGTTITIDD LFRDGYKAIF IGTGVWKPNT LHIKGESLGN VHFAINYLTN PDVYTLGETL NVIGAGNSAM DVARTALRHG CKKVTVFSRS EKLAASVTEV EYAKFDGVDF VMGVEPVEIT DNGTIFVSVE KDEEGNRKRI EGSEKLYPAD STIIAVSQGP RDRIVSTTTG LDVTDRGLLV TNTYGKTTRD GIFAAGDVVR GARTVVEAVN YSKQVADTMD EYLRSL HMM: 4-44 IITEA RRCLNCKNPG CKKGCPISTP IPDVIRTFLD GDIDKA ALI: 108-146 I HVGVIGGGPA GITIAILLAQ RGYNITLFES REKIGGVL ENV: 105-161 KNNI HVGVIGGGPA GITIAILLAQ RGYNITLFES REKIGGVLRY GIPEFRLPKQ LLE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400
Sequence: MAFNIITEA RRCLNCKNPG CKKGCPISTP IPDVIRTFLD GDIDKAGGML FENNPLSVIC SLICNHDNQC EGNCVLGRKG SPVHFSDIEN YISDTYFDKL QFGEIKKNNI HVGVIGGGPA GITIAILLAQ RGYNITLFES REKIGGVLRY GIPEFRLPKQ LLERYKKLMI SLGIKIRPNT SIGTTITIDD LFRDGYKAIF IGTGVWKPNT LHIKGESLGN VHFAINYLTN PDVYTLGETL NVIGAGNSAM DVARTALRHG CKKVTVFSRS EKLAASVTEV EYAKFDGVDF VMGVEPVEIT DNGTIFVSVE KDEEGNRKRI EGSEKLYPAD STIIAVSQGP RDRIVSTTTG LDVTDRGLLV TNTYGKTTRD GIFAAGDVVR GARTVVEAVN YSKQVADTMD EYLRSL HMM: 176-221 PNT SIGTTITIDD LFRDGYKAIF IGTGVWKPNT LHIKGESLGN VHF ALI: 236-281 ETL NVIGAGNSAM DVARTALRHG CKKVTVFSRS EKLAASVTEV EYA ENV: 205-293 KPNT LHIKGESLGN VHFAINYLTN PDVYTLGETL NVIGAGNSAM DVARTALRHG CKKVTVFSRS EKLAASVTEV EYAKFDGVDF VMGVE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400
Sequence: MGKPTGFLE YNRAETAART PLDRIKDFNE FHTEISAEHR CEQAARCMDC GVPFCQNGKL IGGMISGCPL NNLIPEWNEL LYRGKKEQAL MRLLETNNFP EFTSRVCPAL CEKACICGIH DDPVTVRENE KAIIENGFST GLIKPRIPLN RSGKKIAVIG SGPSGLAAAD SLNRRGHNVT VFERSDRAGG LLMYGIPNMK LEKDIVTRRT ALMELEGVEI RTSCDVGIDI SADEILADYD AVILACGSSQ PRDITAAGRD ANGIHFAVDF LKATTKSLLD SDLKDGSYIS AKDKDVVVIG GGDTGNDCVG TAVRHGCKSV TQLEMMPKLP DTRAANNPFP EYPRVCKTDY GQEEAIAVFG SDPRIYETTV KEFIKNDNGE LEAIKTVKVR FENKDGRRVL VEVEGSEQVI PCQLCLIAAG FTGCQSYIAD AFGVELNVRT NVSTAEGSFA SSAEKVFTAG DMHIGQSLVV RAIREGRDCA AEVDRFLMGY TNL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490
PF14691: 22-135 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF07992: 152-475 ◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
Sequence: MGKPTGFLE YNRAETAART PLDRIKDFNE FHTEISAEHR CEQAARCMDC GVPFCQNGKL IGGMISGCPL NNLIPEWNEL LYRGKKEQAL MRLLETNNFP EFTSRVCPAL CEKACICGIH DDPVTVRENE KAIIENGFST GLIKPRIPLN RSGKKIAVIG SGPSGLAAAD SLNRRGHNVT VFERSDRAGG LLMYGIPNMK LEKDIVTRRT ALMELEGVEI RTSCDVGIDI SADEILADYD AVILACGSSQ PRDITAAGRD ANGIHFAVDF LKATTKSLLD SDLKDGSYIS AKDKDVVVIG GGDTGNDCVG TAVRHGCKSV TQLEMMPKLP DTRAANNPFP EYPRVCKTDY GQEEAIAVFG SDPRIYETTV KEFIKNDNGE LEAIKTVKVR FENKDGRRVL VEVEGSEQVI PCQLCLIAAG FTGCQSYIAD AFGVELNVRT NVSTAEGSFA SSAEKVFTAG DMHIGQSLVV RAIREGRDCA AEVDRFLMGY TNL HMM: 175-211 HNVT VFERSDRAGG LLMYGIPNMK LEKDIVTRRT ALM ALI: 149-185 RSGKKIAVIG SGPSGLAAAD SLNRRGHNVT VFERSDR ENV: 133-207 ENGFST GLIKPRIPLN RSGKKIAVIG SGPSGLAAAD SLNRRGHNVT VFERSDRAGG LLMYGIPNMK LEKDIVTRR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490
Sequence: MGKPTGFLE YNRAETAART PLDRIKDFNE FHTEISAEHR CEQAARCMDC GVPFCQNGKL IGGMISGCPL NNLIPEWNEL LYRGKKEQAL MRLLETNNFP EFTSRVCPAL CEKACICGIH DDPVTVRENE KAIIENGFST GLIKPRIPLN RSGKKIAVIG SGPSGLAAAD SLNRRGHNVT VFERSDRAGG LLMYGIPNMK LEKDIVTRRT ALMELEGVEI RTSCDVGIDI SADEILADYD AVILACGSSQ PRDITAAGRD ANGIHFAVDF LKATTKSLLD SDLKDGSYIS AKDKDVVVIG GGDTGNDCVG TAVRHGCKSV TQLEMMPKLP DTRAANNPFP EYPRVCKTDY GQEEAIAVFG SDPRIYETTV KEFIKNDNGE LEAIKTVKVR FENKDGRRVL VEVEGSEQVI PCQLCLIAAG FTGCQSYIAD AFGVELNVRT NVSTAEGSFA SSAEKVFTAG DMHIGQSLVV RAIREGRDCA AEVDRFLMGY TNL HMM: 177-210 VT VFERSDRAGG LLMYGIPNMK LEKDIVTRRT AL ALI: 291-325 DKDVVVIG GGDTGNDCVG TAVRHGCKSV TQLEMMP ENV: 286-335 YIS AKDKDVVVIG GGDTGNDCVG TAVRHGCKSV TQLEMMPKLP DTRAANN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490
Sequence: MGKPTGFLE YNRAETAART PLDRIKDFNE FHTEISAEHR CEQAARCMDC GVPFCQNGKL IGGMISGCPL NNLIPEWNEL LYRGKKEQAL MRLLETNNFP EFTSRVCPAL CEKACICGIH DDPVTVRENE KAIIENGFST GLIKPRIPLN RSGKKIAVIG SGPSGLAAAD SLNRRGHNVT VFERSDRAGG LLMYGIPNMK LEKDIVTRRT ALMELEGVEI RTSCDVGIDI SADEILADYD AVILACGSSQ PRDITAAGRD ANGIHFAVDF LKATTKSLLD SDLKDGSYIS AKDKDVVVIG GGDTGNDCVG TAVRHGCKSV TQLEMMPKLP DTRAANNPFP EYPRVCKTDY GQEEAIAVFG SDPRIYETTV KEFIKNDNGE LEAIKTVKVR FENKDGRRVL VEVEGSEQVI PCQLCLIAAG FTGCQSYIAD AFGVELNVRT NVSTAEGSFA SSAEKVFTAG DMHIGQSLVV RAIREGRDCA AEVDRFLMGY TNL HMM: 171-210 NRRGHNVT VFERSDRAGG LLMYGIPNMK LEKDIVTRRT AL ALI: 147-185 LN RSGKKIAVIG SGPSGLAAAD SLNRRGHNVT VFERSDR ENV: 132-209 IENGFST GLIKPRIPLN RSGKKIAVIG SGPSGLAAAD SLNRRGHNVT VFERSDRAGG LLMYGIPNMK LEKDIVTRRT A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490
Sequence: MGKPTGFLE YNRAETAART PLDRIKDFNE FHTEISAEHR CEQAARCMDC GVPFCQNGKL IGGMISGCPL NNLIPEWNEL LYRGKKEQAL MRLLETNNFP EFTSRVCPAL CEKACICGIH DDPVTVRENE KAIIENGFST GLIKPRIPLN RSGKKIAVIG SGPSGLAAAD SLNRRGHNVT VFERSDRAGG LLMYGIPNMK LEKDIVTRRT ALMELEGVEI RTSCDVGIDI SADEILADYD AVILACGSSQ PRDITAAGRD ANGIHFAVDF LKATTKSLLD SDLKDGSYIS AKDKDVVVIG GGDTGNDCVG TAVRHGCKSV TQLEMMPKLP DTRAANNPFP EYPRVCKTDY GQEEAIAVFG SDPRIYETTV KEFIKNDNGE LEAIKTVKVR FENKDGRRVL VEVEGSEQVI PCQLCLIAAG FTGCQSYIAD AFGVELNVRT NVSTAEGSFA SSAEKVFTAG DMHIGQSLVV RAIREGRDCA AEVDRFLMGY TNL HMM: 174-210 GHNVT VFERSDRAGG LLMYGIPNMK LEKDIVTRRT AL ALI: 290-326 KDKDVVVIG GGDTGNDCVG TAVRHGCKSV TQLEMMPK ENV: 282-333 KDGSYIS AKDKDVVVIG GGDTGNDCVG TAVRHGCKSV TQLEMMPKLP DTRAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490
Sequence: MREFDIVIV GGGPAGMAAA VSARENGMEN IIIFERDSEL GGILNQCIHN GFGLHTFKEE LTGPEYAERY AEMVRAMNIP YETDTMVLDI SKDRVVTVMS RKRGVEEIRA KAVILAMGCR ERPRGALNIP GFRPQGVYTA GTAQKLVNCE GYVPGKEVVI LGSGDIGLIM ARRMTLEGAH VAAVAELMPY SSGLKRNIVQ CLEDYGIPLL LSHTVVDIKG KEKLEGVVIA EVDGKNTPIP GTEKLYPCDT LLLSCGLIPE NELSKNCGVG IDPRTNGPVV DEGLETDIDG VFACGNVLHV HDLVDFVSEE SARAGASAAA FVKRGCTADS TAAVKVIPQN GVRYTVPAEI HTSELLGDVH IRFRVTGVFK DRSIVIKAGD EELIRRKSRI LVPSEMLDII IKKEKLEGVN CDITAAIEEV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
PF07992: 3-297 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MREFDIVIV GGGPAGMAAA VSARENGMEN IIIFERDSEL GGILNQCIHN GFGLHTFKEE LTGPEYAERY AEMVRAMNIP YETDTMVLDI SKDRVVTVMS RKRGVEEIRA KAVILAMGCR ERPRGALNIP GFRPQGVYTA GTAQKLVNCE GYVPGKEVVI LGSGDIGLIM ARRMTLEGAH VAAVAELMPY SSGLKRNIVQ CLEDYGIPLL LSHTVVDIKG KEKLEGVVIA EVDGKNTPIP GTEKLYPCDT LLLSCGLIPE NELSKNCGVG IDPRTNGPVV DEGLETDIDG VFACGNVLHV HDLVDFVSEE SARAGASAAA FVKRGCTADS TAAVKVIPQN GVRYTVPAEI HTSELLGDVH IRFRVTGVFK DRSIVIKAGD EELIRRKSRI LVPSEMLDII IKKEKLEGVN CDITAAIEEV HMM: 5-46 IVIV GGGPAGMAAA VSARENGMEN IIIFERDSEL GGILNQCI ALI: 3-43 FDIVIV GGGPAGMAAA VSARENGMEN IIIFERDSEL GGILN ENV: 1-51 REFDIVIV GGGPAGMAAA VSARENGMEN IIIFERDSEL GGILNQCIHN GFG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MREFDIVIV GGGPAGMAAA VSARENGMEN IIIFERDSEL GGILNQCIHN GFGLHTFKEE LTGPEYAERY AEMVRAMNIP YETDTMVLDI SKDRVVTVMS RKRGVEEIRA KAVILAMGCR ERPRGALNIP GFRPQGVYTA GTAQKLVNCE GYVPGKEVVI LGSGDIGLIM ARRMTLEGAH VAAVAELMPY SSGLKRNIVQ CLEDYGIPLL LSHTVVDIKG KEKLEGVVIA EVDGKNTPIP GTEKLYPCDT LLLSCGLIPE NELSKNCGVG IDPRTNGPVV DEGLETDIDG VFACGNVLHV HDLVDFVSEE SARAGASAAA FVKRGCTADS TAAVKVIPQN GVRYTVPAEI HTSELLGDVH IRFRVTGVFK DRSIVIKAGD EELIRRKSRI LVPSEMLDII IKKEKLEGVN CDITAAIEEV HMM: 177-207 AH VAAVAELMPY SSGLKRNIVQ CLEDYGIPL ALI: 153-183 GKEVVI LGSGDIGLIM ARRMTLEGAH VAAVA ENV: 143-193 KLVNCE GYVPGKEVVI LGSGDIGLIM ARRMTLEGAH VAAVAELMPY SSGLK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MERNWFDEE WKGFKPGRWS STSVNLRDFI QKNFTPYDGD ESFLAGPTEA TNKLWEQVTE LSRQEREAGG VLDMDTKIVS TITSHEAGYL NKDLEKIVGF QTDKPFKRSL QPFGGLRMAQ AACKQYGYEV DPEIVKIFTE YRKTHNQGVF DAYTPEMKLA RHAAILTGLP DAYGRGRIIG DYRRVALYGV DYLIMDKKDQ LDNSLVRMTS KNIRLREELA EQIRALGELK KLGEIYGCDI SRPAKNAQEA IQWLYFGYLA AVKEQNGAAM SLGRTSTFID IYIQRDIESG VLTEEEAQEL VDHFIMKLRL VKFARTPEYN SLFSGDPTWV TESIGGVSID GVPMVTKTSF RYLNTLNNLG PAPEPNMTVL WSVKLPENFK KFCARMSIRT SAIQYENDDL MRATHGDDYA VACCVSSMVV GKEMQFFGAR ANLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPFRHAQD GISNTFSIIP GALGKDDEMF VGDIDIASIA EDLNNGN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
PF02901: 26-621 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF01228: 637-687 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
Sequence: MERNWFDEE WKGFKPGRWS STSVNLRDFI QKNFTPYDGD ESFLAGPTEA TNKLWEQVTE LSRQEREAGG VLDMDTKIVS TITSHEAGYL NKDLEKIVGF QTDKPFKRSL QPFGGLRMAQ AACKQYGYEV DPEIVKIFTE YRKTHNQGVF DAYTPEMKLA RHAAILTGLP DAYGRGRIIG DYRRVALYGV DYLIMDKKDQ LDNSLVRMTS KNIRLREELA EQIRALGELK KLGEIYGCDI SRPAKNAQEA IQWLYFGYLA AVKEQNGAAM SLGRTSTFID IYIQRDIESG VLTEEEAQEL VDHFIMKLRL VKFARTPEYN SLFSGDPTWV TESIGGVSID GVPMVTKTSF RYLNTLNNLG PAPEPNMTVL WSVKLPENFK KFCARMSIRT SAIQYENDDL MRATHGDDYA VACCVSSMVV GKEMQFFGAR ANLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPFRHAQD GISNTFSIIP GALGKDDEMF VGDIDIASIA EDLNNGN HMM: 276-737 FID IYIQRDIESG VLTEEEAQEL VDHFIMKLRL VKFARTPEYN SLFSGDPTWV TESIGGVSID GVPMVTKTSF RYLNTLNNLG PAPEPNMTVL WSVKLPENFK KFCARMSIRT SAIQYENDDL MRATHGDDYA VACCVSSMVV GKEMQFFGAR ANLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPFRHAQD GISNTFSIIP GALGKDDEMF VGDIDIASIA EDLNNGN ALI: 227-663 LK KLGEIYGCDI SRPAKNAQEA IQWLYFGYLA AVKEQNGAAM SLGRTSTFID IYIQRDIESG VLTEEEAQEL VDHFIMKLRL VKFARTPEYN SLFSGDPTWV TESIGGVSID GVPMVTKTSF RYLNTLNNLG PAPEPNMTVL WSVKLPENFK KFCARMSIRT SAIQYENDDL MRATHGDDYA VACCVSSMVV GKEMQFFGAR ANLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPF ENV: 202-674 SLVRMTS KNIRLREELA EQIRALGELK KLGEIYGCDI SRPAKNAQEA IQWLYFGYLA AVKEQNGAAM SLGRTSTFID IYIQRDIESG VLTEEEAQEL VDHFIMKLRL VKFARTPEYN SLFSGDPTWV TESIGGVSID GVPMVTKTSF RYLNTLNNLG PAPEPNMTVL WSVKLPENFK KFCARMSIRT SAIQYENDDL MRATHGDDYA VACCVSSMVV GKEMQFFGAR ANLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPFRHAQD GISNTF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MERNWFDEE WKGFKPGRWS STSVNLRDFI QKNFTPYDGD ESFLAGPTEA TNKLWEQVTE LSRQEREAGG VLDMDTKIVS TITSHEAGYL NKDLEKIVGF QTDKPFKRSL QPFGGLRMAQ AACKQYGYEV DPEIVKIFTE YRKTHNQGVF DAYTPEMKLA RHAAILTGLP DAYGRGRIIG DYRRVALYGV DYLIMDKKDQ LDNSLVRMTS KNIRLREELA EQIRALGELK KLGEIYGCDI SRPAKNAQEA IQWLYFGYLA AVKEQNGAAM SLGRTSTFID IYIQRDIESG VLTEEEAQEL VDHFIMKLRL VKFARTPEYN SLFSGDPTWV TESIGGVSID GVPMVTKTSF RYLNTLNNLG PAPEPNMTVL WSVKLPENFK KFCARMSIRT SAIQYENDDL MRATHGDDYA VACCVSSMVV GKEMQFFGAR ANLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPFRHAQD GISNTFSIIP GALGKDDEMF VGDIDIASIA EDLNNGN HMM: 284-756 DIESG VLTEEEAQEL VDHFIMKLRL VKFARTPEYN SLFSGDPTWV TESIGGVSID GVPMVTKTSF RYLNTLNNLG PAPEPNMTVL WSVKLPENFK KFCARMSIRT SAIQYENDDL MRATHGDDYA VACCVSSMVV GKEMQFFGAR ANLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPFRHAQD GISNTFSIIP GALGKDDEMF VGDIDIASIA EDLNNGN ALI: 227-663 LK KLGEIYGCDI SRPAKNAQEA IQWLYFGYLA AVKEQNGAAM SLGRTSTFID IYIQRDIESG VLTEEEAQEL VDHFIMKLRL VKFARTPEYN SLFSGDPTWV TESIGGVSID GVPMVTKTSF RYLNTLNNLG PAPEPNMTVL WSVKLPENFK KFCARMSIRT SAIQYENDDL MRATHGDDYA VACCVSSMVV GKEMQFFGAR ANLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPF ENV: 202-676 SLVRMTS KNIRLREELA EQIRALGELK KLGEIYGCDI SRPAKNAQEA IQWLYFGYLA AVKEQNGAAM SLGRTSTFID IYIQRDIESG VLTEEEAQEL VDHFIMKLRL VKFARTPEYN SLFSGDPTWV TESIGGVSID GVPMVTKTSF RYLNTLNNLG PAPEPNMTVL WSVKLPENFK KFCARMSIRT SAIQYENDDL MRATHGDDYA VACCVSSMVV GKEMQFFGAR ANLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPFRHAQD GISNTFSI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MERNWFDEE WKGFKPGRWS STSVNLRDFI QKNFTPYDGD ESFLAGPTEA TNKLWEQVTE LSRQEREAGG VLDMDTKIVS TITSHEAGYL NKDLEKIVGF QTDKPFKRSL QPFGGLRMAQ AACKQYGYEV DPEIVKIFTE YRKTHNQGVF DAYTPEMKLA RHAAILTGLP DAYGRGRIIG DYRRVALYGV DYLIMDKKDQ LDNSLVRMTS KNIRLREELA EQIRALGELK KLGEIYGCDI SRPAKNAQEA IQWLYFGYLA AVKEQNGAAM SLGRTSTFID IYIQRDIESG VLTEEEAQEL VDHFIMKLRL VKFARTPEYN SLFSGDPTWV TESIGGVSID GVPMVTKTSF RYLNTLNNLG PAPEPNMTVL WSVKLPENFK KFCARMSIRT SAIQYENDDL MRATHGDDYA VACCVSSMVV GKEMQFFGAR ANLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPFRHAQD GISNTFSIIP GALGKDDEMF VGDIDIASIA EDLNNGN HMM: 483-729 YVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPFRHAQD GISNTFSIIP GALGKDDEMF VGDIDIASIA EDLNNGN ALI: 430-666 NLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPFRHA ENV: 404-675 GDDYA VACCVSSMVV GKEMQFFGAR ANLAKCLLYA INGGVDERLG VQVGPKYRPV DSEYLDFDDV MEKYDDMMEW LAGLYVNTLN VIHFMHDKYS YERIQMALHD RDVKRYFATG IAGLSVVADS LSAIKYAKVK PVRKDIEIRD KAGNVVDVAR NVVVDYIVEG DFPKYGNNDD RVDKLAVDIV KRFMNKIRKH HTYRDGVPTM SILTITSNVV YGKKTGSTSD GRKIGVPLAP GANPMHGRDT HGAASSLASV AKLPFRHAQD GISNTFS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700
Sequence: MANFEPTDA QVDNLIGLLD GYAEKGGHHL NVNVLNRETL LDAQAHPEKY PQLTIRVSGY AVNFVKLTKE QQDDVISRTF HESL
10 20 30 40 50 60 70 80
PF01228: 7-64 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MANFEPTDA QVDNLIGLLD GYAEKGGHHL NVNVLNRETL LDAQAHPEKY PQLTIRVSGY AVNFVKLTKE QQDDVISRTF HESL HMM: 770-831 ALI: 19-80 GYAEKGGHHL NVNVLNRETL LDAQAHPEKY PQLTIRVSGY AVNFVKLTKE QQDDVISRTF HE ENV: 14-82 IGLLD GYAEKGGHHL NVNVLNRETL LDAQAHPEKY PQLTIRVSGY AVNFVKLTKE QQDDVISRTF HESL Position: 10 20 30 40 50 60 70 80
Sequence: MANFEPTDA QVDNLIGLLD GYAEKGGHHL NVNVLNRETL LDAQAHPEKY PQLTIRVSGY AVNFVKLTKE QQDDVISRTF HESL HMM: 787-847 ALI: 19-79 GYAEKGGHHL NVNVLNRETL LDAQAHPEKY PQLTIRVSGY AVNFVKLTKE QQDDVISRTF H ENV: 8-82 A QVDNLIGLLD GYAEKGGHHL NVNVLNRETL LDAQAHPEKY PQLTIRVSGY AVNFVKLTKE QQDDVISRTF HESL Position: 10 20 30 40 50 60 70 80
Sequence: MANFEPTDA QVDNLIGLLD GYAEKGGHHL NVNVLNRETL LDAQAHPEKY PQLTIRVSGY AVNFVKLTKE QQDDVISRTF HESL HMM: 763-818 ALI: 24-79 GGHHL NVNVLNRETL LDAQAHPEKY PQLTIRVSGY AVNFVKLTKE QQDDVISRTF H ENV: 10-82 VDNLIGLLD GYAEKGGHHL NVNVLNRETL LDAQAHPEKY PQLTIRVSGY AVNFVKLTKE QQDDVISRTF HESL Position: 10 20 30 40 50 60 70 80
Sequence: MSMDRLIEN IVKTQNPSVV GLDPKLEYVP EFIKEKKFKK YDRTLKAAAK AILEFNKCII DEIHDICPAI KPQAAYYEMY GYEGVKTLYK TIQYAKEKGM FVMTDGKRND IGATMEAYAA AHLGLTDVGG EKIEAFGADA LTVNGYLGSD GINPLLEQCK LYDKGIFVLV KTSNKSSGEL QDLKIGDKTV YATMGDMCEK WGSEVMGKYG YSGVGAVVGA TYPEQLAEMR AALPHTFFLV PGYGAQGGGA EGVSKGFDKN GLGAIVNSSR GVMCAYKKEE CDEQDFAKAA RREVIRMKED IISYLPRIAF PD
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310
PF00215: 57-279 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MSMDRLIEN IVKTQNPSVV GLDPKLEYVP EFIKEKKFKK YDRTLKAAAK AILEFNKCII DEIHDICPAI KPQAAYYEMY GYEGVKTLYK TIQYAKEKGM FVMTDGKRND IGATMEAYAA AHLGLTDVGG EKIEAFGADA LTVNGYLGSD GINPLLEQCK LYDKGIFVLV KTSNKSSGEL QDLKIGDKTV YATMGDMCEK WGSEVMGKYG YSGVGAVVGA TYPEQLAEMR AALPHTFFLV PGYGAQGGGA EGVSKGFDKN GLGAIVNSSR GVMCAYKKEE CDEQDFAKAA RREVIRMKED IISYLPRIAF PD HMM: 101-172 MTDGKRND IGATMEAYAA AHLGLTDVGG EKIEAFGADA LTVNGYLGSD GINPLLEQCK LYDKGIFVLV KTSN ALI: 191-262 TMGDMCEK WGSEVMGKYG YSGVGAVVGA TYPEQLAEMR AALPHTFFLV PGYGAQGGGA EGVSKGFDKN GLGA ENV: 165-273 FVLV KTSNKSSGEL QDLKIGDKTV YATMGDMCEK WGSEVMGKYG YSGVGAVVGA TYPEQLAEMR AALPHTFFLV PGYGAQGGGA EGVSKGFDKN GLGAIVNSSR GVMCA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310
Sequence: MEKAVRVDM LDFDFWTILF SVINILVLFF FLKKFLFGRV NAMLEKRAQM VQADMDEAKQ HAADAEKLKN AYEETLSGAK QEAKQIIATA EQNAHAQGSE ITAKAQQQAD TLLKEAQKEI ERERRQTLDG VQGEIADLAL AAASKLMEQK VDDQTNRELV NAFLSEEGAG E
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170
PF00430: 15-147 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
Sequence: MEKAVRVDM LDFDFWTILF SVINILVLFF FLKKFLFGRV NAMLEKRAQM VQADMDEAKQ HAADAEKLKN AYEETLSGAK QEAKQIIATA EQNAHAQGSE ITAKAQQQAD TLLKEAQKEI ERERRQTLDG VQGEIADLAL AAASKLMEQK VDDQTNRELV NAFLSEEGAG E HMM: 358-471 ALI: 42-155 LEKRAQM VQADMDEAKQ HAADAEKLKN AYEETLSGAK QEAKQIIATA EQNAHAQGSE ITAKAQQQAD TLLKEAQKEI ERERRQTLDG VQGEIADLAL AAASKLMEQK VDDQTNR ENV: 15-166 TILF SVINILVLFF FLKKFLFGRV NAMLEKRAQM VQADMDEAKQ HAADAEKLKN AYEETLSGAK QEAKQIIATA EQNAHAQGSE ITAKAQQQAD TLLKEAQKEI ERERRQTLDG VQGEIADLAL AAASKLMEQK VDDQTNRELV NAFLSEEG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170
Sequence: MQQYTTDIM IIGGGASGLA AAVAAKRFCP ELSVMILERN SRVGKKILAT GNGRCNLGNI STDSRYYYGS CKKYWNTIVE QTQPAEAFFQ SMGLYCRRES DGRLYPCSNQ AASVLDALRL TIEQEGISDV CYCLVSDIQQ TESGILAKTT QGDFLASAAI VTTGGFAAPK TGSDGSAFSW LLNLGHHCNT PKPALVPFLT KPVLLRLLKG IRLSAEVTAI SENGTVLAVD TGEVQFTERT ISGICVMNLS AACVGQEPAA ICLRLLPEIP EQRLLPLLWE LYGVRTNWKL EDWLTGLLPK KAGIQLLRSA GIAMSMDTPV YEITPQQLEQ VAKTILSWKF PVLSRGSWQE AQVTSGGIPA EEIDADLQSR LVNGLFFAGE ILDFHGNCGG YNLNWAWQSG QFSGENAAKQ ILQKRGDTV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
PF03486: 6-404 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MQQYTTDIM IIGGGASGLA AAVAAKRFCP ELSVMILERN SRVGKKILAT GNGRCNLGNI STDSRYYYGS CKKYWNTIVE QTQPAEAFFQ SMGLYCRRES DGRLYPCSNQ AASVLDALRL TIEQEGISDV CYCLVSDIQQ TESGILAKTT QGDFLASAAI VTTGGFAAPK TGSDGSAFSW LLNLGHHCNT PKPALVPFLT KPVLLRLLKG IRLSAEVTAI SENGTVLAVD TGEVQFTERT ISGICVMNLS AACVGQEPAA ICLRLLPEIP EQRLLPLLWE LYGVRTNWKL EDWLTGLLPK KAGIQLLRSA GIAMSMDTPV YEITPQQLEQ VAKTILSWKF PVLSRGSWQE AQVTSGGIPA EEIDADLQSR LVNGLFFAGE ILDFHGNCGG YNLNWAWQSG QFSGENAAKQ ILQKRGDTV HMM: 1-43 QQYTTDIM IIGGGASGLA AAVAAKRFCP ELSVMILERN SRVGK ALI: 1-43 QQYTTDIM IIGGGASGLA AAVAAKRFCP ELSVMILERN SRVGK ENV: 1-47 QQYTTDIM IIGGGASGLA AAVAAKRFCP ELSVMILERN SRVGKKILA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MQQYTTDIM IIGGGASGLA AAVAAKRFCP ELSVMILERN SRVGKKILAT GNGRCNLGNI STDSRYYYGS CKKYWNTIVE QTQPAEAFFQ SMGLYCRRES DGRLYPCSNQ AASVLDALRL TIEQEGISDV CYCLVSDIQQ TESGILAKTT QGDFLASAAI VTTGGFAAPK TGSDGSAFSW LLNLGHHCNT PKPALVPFLT KPVLLRLLKG IRLSAEVTAI SENGTVLAVD TGEVQFTERT ISGICVMNLS AACVGQEPAA ICLRLLPEIP EQRLLPLLWE LYGVRTNWKL EDWLTGLLPK KAGIQLLRSA GIAMSMDTPV YEITPQQLEQ VAKTILSWKF PVLSRGSWQE AQVTSGGIPA EEIDADLQSR LVNGLFFAGE ILDFHGNCGG YNLNWAWQSG QFSGENAAKQ ILQKRGDTV HMM: 4-42 TTDIM IIGGGASGLA AAVAAKRFCP ELSVMILERN SRVG ALI: 5-43 TDIM IIGGGASGLA AAVAAKRFCP ELSVMILERN SRVGK ENV: 1-50 QQYTTDIM IIGGGASGLA AAVAAKRFCP ELSVMILERN SRVGKKILAT GN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MYDIIIIGS GPAGLTAAIY ASRARLQTLV LERDTMGAGQ IAVTEQVDNY PGLPHIGGYE LGEKFREHAT ELGTLFCEND VTHLEKKDGY FTATLEDHTE LQARSVIYAA GTSYRRLEIA GGRLAGVSYC ATCDGAFYQG KVVAVIGGGD TALEDALYLS RMAKTVYLVH RRDTFRANAA LQEAVQKTEN IVLVTNAVPT EITGEKRVET LKLLHGGSPE ELSLDGVFVA IGSVPNTSLL EGVAELDSSG YVQAGEDGRT SVEGLFAAGD VRTKALRQVI TAAADGANCV ASAEKYLLEN RG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
PF07992: 1-285 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
Sequence: MYDIIIIGS GPAGLTAAIY ASRARLQTLV LERDTMGAGQ IAVTEQVDNY PGLPHIGGYE LGEKFREHAT ELGTLFCEND VTHLEKKDGY FTATLEDHTE LQARSVIYAA GTSYRRLEIA GGRLAGVSYC ATCDGAFYQG KVVAVIGGGD TALEDALYLS RMAKTVYLVH RRDTFRANAA LQEAVQKTEN IVLVTNAVPT EITGEKRVET LKLLHGGSPE ELSLDGVFVA IGSVPNTSLL EGVAELDSSG YVQAGEDGRT SVEGLFAAGD VRTKALRQVI TAAADGANCV ASAEKYLLEN RG HMM: 6-68 IGS GPAGLTAAIY ASRARLQTLV LERDTMGAGQ IAVTEQVDNY PGLPHIGGYE LGEKFREHAT ALI: 2-65 DIIIIGS GPAGLTAAIY ASRARLQTLV LERDTMGAGQ IAVTEQVDNY PGLPHIGGYE LGEKFRE ENV: 1-74 YDIIIIGS GPAGLTAAIY ASRARLQTLV LERDTMGAGQ IAVTEQVDNY PGLPHIGGYE LGEKFREHAT ELGTLF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MYDIIIIGS GPAGLTAAIY ASRARLQTLV LERDTMGAGQ IAVTEQVDNY PGLPHIGGYE LGEKFREHAT ELGTLFCEND VTHLEKKDGY FTATLEDHTE LQARSVIYAA GTSYRRLEIA GGRLAGVSYC ATCDGAFYQG KVVAVIGGGD TALEDALYLS RMAKTVYLVH RRDTFRANAA LQEAVQKTEN IVLVTNAVPT EITGEKRVET LKLLHGGSPE ELSLDGVFVA IGSVPNTSLL EGVAELDSSG YVQAGEDGRT SVEGLFAAGD VRTKALRQVI TAAADGANCV ASAEKYLLEN RG HMM: 176-226 NAA LQEAVQKTEN IVLVTNAVPT EITGEKRVET LKLLHGGSPE ELSLDGVF ALI: 137-187 QG KVVAVIGGGD TALEDALYLS RMAKTVYLVH RRDTFRANAA LQEAVQKTE ENV: 130-199 TCDGAFYQG KVVAVIGGGD TALEDALYLS RMAKTVYLVH RRDTFRANAA LQEAVQKTEN IVLVTNAVPT E Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MNIAVAGTG YVGLSIATLL AQHNKVTAVD IIPEKVELIR QKKSPIQDDY IEKYLAEKEL DLTATLDAEA AYRDADFVVI AAPTNYDGKK NFFDTSAVEA VIALVMQYNP NAIMVIKSTI PVGYTKSIRE KTGSKNIIFS PEFLRESKAL YDNLYPSRII VGTDMDDARL VEAAHTFAGL LQQGAIKENI DTLFMGFTEA EAVKLFANTY LALRVSYFNE LDTYAELKGL DTQQIIDGVC LDPRIGTHYN NPSFGYGGYC LPKDTKQLLA NYADVPQNMM SAIVESNRTR KDFIADRVLE KAGYYDYSQN NDWNAGTEKQ VTIGVYRLTM KSNSDNFRQS SIQGVMKRVK AKGATVIIYE PTLQDGATFF GSVVVNDLEK FKAAADAIIA NRYDACLDDV ENKVYTRDIF RRD
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
PF03721: 0-168 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00984: 197-287 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
PF03720: 323-398 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MNIAVAGTG YVGLSIATLL AQHNKVTAVD IIPEKVELIR QKKSPIQDDY IEKYLAEKEL DLTATLDAEA AYRDADFVVI AAPTNYDGKK NFFDTSAVEA VIALVMQYNP NAIMVIKSTI PVGYTKSIRE KTGSKNIIFS PEFLRESKAL YDNLYPSRII VGTDMDDARL VEAAHTFAGL LQQGAIKENI DTLFMGFTEA EAVKLFANTY LALRVSYFNE LDTYAELKGL DTQQIIDGVC LDPRIGTHYN NPSFGYGGYC LPKDTKQLLA NYADVPQNMM SAIVESNRTR KDFIADRVLE KAGYYDYSQN NDWNAGTEKQ VTIGVYRLTM KSNSDNFRQS SIQGVMKRVK AKGATVIIYE PTLQDGATFF GSVVVNDLEK FKAAADAIIA NRYDACLDDV ENKVYTRDIF RRD HMM: 6-36 GTG YVGLSIATLL AQHNKVTAVD IIPEKVEL ALI: 2-32 IAVAGTG YVGLSIATLL AQHNKVTAVD IIPE ENV: 1-38 NIAVAGTG YVGLSIATLL AQHNKVTAVD IIPEKVELIR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MNIAVAGTG YVGLSIATLL AQHNKVTAVD IIPEKVELIR QKKSPIQDDY IEKYLAEKEL DLTATLDAEA AYRDADFVVI AAPTNYDGKK NFFDTSAVEA VIALVMQYNP NAIMVIKSTI PVGYTKSIRE KTGSKNIIFS PEFLRESKAL YDNLYPSRII VGTDMDDARL VEAAHTFAGL LQQGAIKENI DTLFMGFTEA EAVKLFANTY LALRVSYFNE LDTYAELKGL DTQQIIDGVC LDPRIGTHYN NPSFGYGGYC LPKDTKQLLA NYADVPQNMM SAIVESNRTR KDFIADRVLE KAGYYDYSQN NDWNAGTEKQ VTIGVYRLTM KSNSDNFRQS SIQGVMKRVK AKGATVIIYE PTLQDGATFF GSVVVNDLEK FKAAADAIIA NRYDACLDDV ENKVYTRDIF RRD HMM: 303-341 YDYSQN NDWNAGTEKQ VTIGVYRLTM KSNSDNFRQS SIQ ALI: 36-80 LIR QKKSPIQDDY IEKYLAEKEL DLTATLDAEA AYRDADFVVI AA ENV: 26-108 AVD IIPEKVELIR QKKSPIQDDY IEKYLAEKEL DLTATLDAEA AYRDADFVVI AAPTNYDGKK NFFDTSAVEA VIALVMQYNP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MNIAVAGTG YVGLSIATLL AQHNKVTAVD IIPEKVELIR QKKSPIQDDY IEKYLAEKEL DLTATLDAEA AYRDADFVVI AAPTNYDGKK NFFDTSAVEA VIALVMQYNP NAIMVIKSTI PVGYTKSIRE KTGSKNIIFS PEFLRESKAL YDNLYPSRII VGTDMDDARL VEAAHTFAGL LQQGAIKENI DTLFMGFTEA EAVKLFANTY LALRVSYFNE LDTYAELKGL DTQQIIDGVC LDPRIGTHYN NPSFGYGGYC LPKDTKQLLA NYADVPQNMM SAIVESNRTR KDFIADRVLE KAGYYDYSQN NDWNAGTEKQ VTIGVYRLTM KSNSDNFRQS SIQGVMKRVK AKGATVIIYE PTLQDGATFF GSVVVNDLEK FKAAADAIIA NRYDACLDDV ENKVYTRDIF RRD HMM: 104-153 MQYNP NAIMVIKSTI PVGYTKSIRE KTGSKNIIFS PEFLRESKAL YDNLY ALI: 266-315 LLA NYADVPQNMM SAIVESNRTR KDFIADRVLE KAGYYDYSQN NDWNAGT ENV: 261-375 KDTKQLLA NYADVPQNMM SAIVESNRTR KDFIADRVLE KAGYYDYSQN NDWNAGTEKQ VTIGVYRLTM KSNSDNFRQS SIQGVMKRVK AKGATVIIYE PTLQDGATFF GSVVVND Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MAETMAKAW EGFVGGAWEK TIDVRDFIQK NYTPYEGDES FLAGPTESTT KLWSEVMDLF QKERENGGVL DMDTKLVSTV DSHEAGYIDK DLETIVGLQT DKPLKRSLQP FGGIRMAEEA CKAYGYEVDP EITYIFTHYR KTHNEGVFDV YTPEMRAARH NAIITGLPDA YGRGRIIGDY RRVALYGIDR LIEDKNYQKA ITSGTMTEEK IRLREELADQ IKALKALKNM AKKYGYDISV PATNAKEAIQ WTYFAYLGAV KDQNGAAMSL GRTSTFLDIY IQRDLDNGTL TEEQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRLPKAFKHY CAKLSINTSS FQYENDDLMR VTHGDDYAIA CCVSSMRVGK EMQFFGARAN LAKCLLYAIN GGVDERLDAK TGKHNQVGPK YRPVEGDYLD YDDVMAKYTD MMTWLAKLYV DTLNCIHYMH DKYCYEAIQM ALHDRDVKRY FATGIAGMSV VADSLSAIKY AKVKCIRDEY GVVTDFEVEG DFPKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQD GISNTFTIIP DALGKDSKVF AGDIDIASIR EEMEKQ
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
PF02901: 19-611 ♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF01228: 627-677 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
Sequence: MAETMAKAW EGFVGGAWEK TIDVRDFIQK NYTPYEGDES FLAGPTESTT KLWSEVMDLF QKERENGGVL DMDTKLVSTV DSHEAGYIDK DLETIVGLQT DKPLKRSLQP FGGIRMAEEA CKAYGYEVDP EITYIFTHYR KTHNEGVFDV YTPEMRAARH NAIITGLPDA YGRGRIIGDY RRVALYGIDR LIEDKNYQKA ITSGTMTEEK IRLREELADQ IKALKALKNM AKKYGYDISV PATNAKEAIQ WTYFAYLGAV KDQNGAAMSL GRTSTFLDIY IQRDLDNGTL TEEQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRLPKAFKHY CAKLSINTSS FQYENDDLMR VTHGDDYAIA CCVSSMRVGK EMQFFGARAN LAKCLLYAIN GGVDERLDAK TGKHNQVGPK YRPVEGDYLD YDDVMAKYTD MMTWLAKLYV DTLNCIHYMH DKYCYEAIQM ALHDRDVKRY FATGIAGMSV VADSLSAIKY AKVKCIRDEY GVVTDFEVEG DFPKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQD GISNTFTIIP DALGKDSKVF AGDIDIASIR EEMEKQ HMM: 291-420 EQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRLPKAFKHY CAKLSINTSS FQYENDDLMR VTHGDDYAIA CCVSSMRVGK EM ALI: 240-370 ATNAKEAIQ WTYFAYLGAV KDQNGAAMSL GRTSTFLDIY IQRDLDNGTL TEEQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KR ENV: 215-380 LADQ IKALKALKNM AKKYGYDISV PATNAKEAIQ WTYFAYLGAV KDQNGAAMSL GRTSTFLDIY IQRDLDNGTL TEEQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRLPKAFKHY CA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAETMAKAW EGFVGGAWEK TIDVRDFIQK NYTPYEGDES FLAGPTESTT KLWSEVMDLF QKERENGGVL DMDTKLVSTV DSHEAGYIDK DLETIVGLQT DKPLKRSLQP FGGIRMAEEA CKAYGYEVDP EITYIFTHYR KTHNEGVFDV YTPEMRAARH NAIITGLPDA YGRGRIIGDY RRVALYGIDR LIEDKNYQKA ITSGTMTEEK IRLREELADQ IKALKALKNM AKKYGYDISV PATNAKEAIQ WTYFAYLGAV KDQNGAAMSL GRTSTFLDIY IQRDLDNGTL TEEQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRLPKAFKHY CAKLSINTSS FQYENDDLMR VTHGDDYAIA CCVSSMRVGK EMQFFGARAN LAKCLLYAIN GGVDERLDAK TGKHNQVGPK YRPVEGDYLD YDDVMAKYTD MMTWLAKLYV DTLNCIHYMH DKYCYEAIQM ALHDRDVKRY FATGIAGMSV VADSLSAIKY AKVKCIRDEY GVVTDFEVEG DFPKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQD GISNTFTIIP DALGKDSKVF AGDIDIASIR EEMEKQ HMM: 476-575 YTD MMTWLAKLYV DTLNCIHYMH DKYCYEAIQM ALHDRDVKRY FATGIAGMSV VADSLSAIKY AKVKCIRDEY GVVTDFEVEG DFPKYGNNDD RVDSIAV ALI: 411-517 VSSMRVGK EMQFFGARAN LAKCLLYAIN GGVDERLDAK TGKHNQVGPK YRPVEGDYLD YDDVMAKYTD MMTWLAKLYV DTLNCIHYMH DKYCYEAIQM ALHDRDVKR ENV: 401-529 HGDDYAIA CCVSSMRVGK EMQFFGARAN LAKCLLYAIN GGVDERLDAK TGKHNQVGPK YRPVEGDYLD YDDVMAKYTD MMTWLAKLYV DTLNCIHYMH DKYCYEAIQM ALHDRDVKRY FATGIAGMSV V Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAETMAKAW EGFVGGAWEK TIDVRDFIQK NYTPYEGDES FLAGPTESTT KLWSEVMDLF QKERENGGVL DMDTKLVSTV DSHEAGYIDK DLETIVGLQT DKPLKRSLQP FGGIRMAEEA CKAYGYEVDP EITYIFTHYR KTHNEGVFDV YTPEMRAARH NAIITGLPDA YGRGRIIGDY RRVALYGIDR LIEDKNYQKA ITSGTMTEEK IRLREELADQ IKALKALKNM AKKYGYDISV PATNAKEAIQ WTYFAYLGAV KDQNGAAMSL GRTSTFLDIY IQRDLDNGTL TEEQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRLPKAFKHY CAKLSINTSS FQYENDDLMR VTHGDDYAIA CCVSSMRVGK EMQFFGARAN LAKCLLYAIN GGVDERLDAK TGKHNQVGPK YRPVEGDYLD YDDVMAKYTD MMTWLAKLYV DTLNCIHYMH DKYCYEAIQM ALHDRDVKRY FATGIAGMSV VADSLSAIKY AKVKCIRDEY GVVTDFEVEG DFPKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQD GISNTFTIIP DALGKDSKVF AGDIDIASIR EEMEKQ HMM: 644-737 SMASV AKLPWKNAQD GISNTFTIIP DALGKDSKVF AGDIDIASIR EEMEKQ ALI: 561-653 PKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPW ENV: 552-662 TDFEVEG DFPKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQD GISN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAETMAKAW EGFVGGAWEK TIDVRDFIQK NYTPYEGDES FLAGPTESTT KLWSEVMDLF QKERENGGVL DMDTKLVSTV DSHEAGYIDK DLETIVGLQT DKPLKRSLQP FGGIRMAEEA CKAYGYEVDP EITYIFTHYR KTHNEGVFDV YTPEMRAARH NAIITGLPDA YGRGRIIGDY RRVALYGIDR LIEDKNYQKA ITSGTMTEEK IRLREELADQ IKALKALKNM AKKYGYDISV PATNAKEAIQ WTYFAYLGAV KDQNGAAMSL GRTSTFLDIY IQRDLDNGTL TEEQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRLPKAFKHY CAKLSINTSS FQYENDDLMR VTHGDDYAIA CCVSSMRVGK EMQFFGARAN LAKCLLYAIN GGVDERLDAK TGKHNQVGPK YRPVEGDYLD YDDVMAKYTD MMTWLAKLYV DTLNCIHYMH DKYCYEAIQM ALHDRDVKRY FATGIAGMSV VADSLSAIKY AKVKCIRDEY GVVTDFEVEG DFPKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQD GISNTFTIIP DALGKDSKVF AGDIDIASIR EEMEKQ HMM: 299-432 HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRLPKAFKHY CAKLSINTSS FQYENDDLMR VTHGDDYAIA CCVSSMRVGK EMQFFGARAN LAKC ALI: 240-371 ATNAKEAIQ WTYFAYLGAV KDQNGAAMSL GRTSTFLDIY IQRDLDNGTL TEEQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRL ENV: 214-387 ELADQ IKALKALKNM AKKYGYDISV PATNAKEAIQ WTYFAYLGAV KDQNGAAMSL GRTSTFLDIY IQRDLDNGTL TEEQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRLPKAFKHY CAKLSINTS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAETMAKAW EGFVGGAWEK TIDVRDFIQK NYTPYEGDES FLAGPTESTT KLWSEVMDLF QKERENGGVL DMDTKLVSTV DSHEAGYIDK DLETIVGLQT DKPLKRSLQP FGGIRMAEEA CKAYGYEVDP EITYIFTHYR KTHNEGVFDV YTPEMRAARH NAIITGLPDA YGRGRIIGDY RRVALYGIDR LIEDKNYQKA ITSGTMTEEK IRLREELADQ IKALKALKNM AKKYGYDISV PATNAKEAIQ WTYFAYLGAV KDQNGAAMSL GRTSTFLDIY IQRDLDNGTL TEEQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRLPKAFKHY CAKLSINTSS FQYENDDLMR VTHGDDYAIA CCVSSMRVGK EMQFFGARAN LAKCLLYAIN GGVDERLDAK TGKHNQVGPK YRPVEGDYLD YDDVMAKYTD MMTWLAKLYV DTLNCIHYMH DKYCYEAIQM ALHDRDVKRY FATGIAGMSV VADSLSAIKY AKVKCIRDEY GVVTDFEVEG DFPKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQD GISNTFTIIP DALGKDSKVF AGDIDIASIR EEMEKQ HMM: 662-756 NTFTIIP DALGKDSKVF AGDIDIASIR EEMEKQ ALI: 561-653 PKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPW ENV: 547-664 EY GVVTDFEVEG DFPKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQD GISNTF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MAETMAKAW EGFVGGAWEK TIDVRDFIQK NYTPYEGDES FLAGPTESTT KLWSEVMDLF QKERENGGVL DMDTKLVSTV DSHEAGYIDK DLETIVGLQT DKPLKRSLQP FGGIRMAEEA CKAYGYEVDP EITYIFTHYR KTHNEGVFDV YTPEMRAARH NAIITGLPDA YGRGRIIGDY RRVALYGIDR LIEDKNYQKA ITSGTMTEEK IRLREELADQ IKALKALKNM AKKYGYDISV PATNAKEAIQ WTYFAYLGAV KDQNGAAMSL GRTSTFLDIY IQRDLDNGTL TEEQAQEYID HFIMKLRMVK FARTPEYNAL FSGDPQWVTE SIGGMGIDGR TLVTKNSFRY LHTLENLGTA PEPNLTVLWS KRLPKAFKHY CAKLSINTSS FQYENDDLMR VTHGDDYAIA CCVSSMRVGK EMQFFGARAN LAKCLLYAIN GGVDERLDAK TGKHNQVGPK YRPVEGDYLD YDDVMAKYTD MMTWLAKLYV DTLNCIHYMH DKYCYEAIQM ALHDRDVKRY FATGIAGMSV VADSLSAIKY AKVKCIRDEY GVVTDFEVEG DFPKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQD GISNTFTIIP DALGKDSKVF AGDIDIASIR EEMEKQ HMM: 614-730 GNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQD GISNTFTIIP DALGKDSKVF AGDIDIASIR EEMEKQ ALI: 543-657 CIRDEY GVVTDFEVEG DFPKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQ ENV: 425-679 ARAN LAKCLLYAIN GGVDERLDAK TGKHNQVGPK YRPVEGDYLD YDDVMAKYTD MMTWLAKLYV DTLNCIHYMH DKYCYEAIQM ALHDRDVKRY FATGIAGMSV VADSLSAIKY AKVKCIRDEY GVVTDFEVEG DFPKYGNNDD RVDSIAVEIL DKFMDMIRSN YCYRGGVPTT SILTITSNVV YGKKTGNTPD GRKKGQPLAP GANPMHGRDT HGAAASMASV AKLPWKNAQD GISNTFTIIP DALGKDSKVF A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690
Sequence: MANEKQIEN LVGLLDGYAE KGGHHLNVNV LNRETLLDAQ AHPEKYPQLT IRVSGYAVNF IKLTKEQQDD VITRTFHASL
10 20 30 40 50 60 70
PF01228: 2-60 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MANEKQIEN LVGLLDGYAE KGGHHLNVNV LNRETLLDAQ AHPEKYPQLT IRVSGYAVNF IKLTKEQQDD VITRTFHASL HMM: 768-830 ALI: 13-75 LDGYAE KGGHHLNVNV LNRETLLDAQ AHPEKYPQLT IRVSGYAVNF IKLTKEQQDD VITRTFH ENV: 1-77 ANEKQIEN LVGLLDGYAE KGGHHLNVNV LNRETLLDAQ AHPEKYPQLT IRVSGYAVNF IKLTKEQQDD VITRTFHAS Position: 10 20 30 40 50 60 70
Sequence: MANEKQIEN LVGLLDGYAE KGGHHLNVNV LNRETLLDAQ AHPEKYPQLT IRVSGYAVNF IKLTKEQQDD VITRTFHASL HMM: 785-846 ALI: 13-74 LDGYAE KGGHHLNVNV LNRETLLDAQ AHPEKYPQLT IRVSGYAVNF IKLTKEQQDD VITRTF ENV: 1-78 ANEKQIEN LVGLLDGYAE KGGHHLNVNV LNRETLLDAQ AHPEKYPQLT IRVSGYAVNF IKLTKEQQDD VITRTFHASL Position: 10 20 30 40 50 60 70
Sequence: MANEKQIEN LVGLLDGYAE KGGHHLNVNV LNRETLLDAQ AHPEKYPQLT IRVSGYAVNF IKLTKEQQDD VITRTFHASL HMM: 746-817 ALI: 3-74 EKQIEN LVGLLDGYAE KGGHHLNVNV LNRETLLDAQ AHPEKYPQLT IRVSGYAVNF IKLTKEQQDD VITRTF ENV: 1-78 ANEKQIEN LVGLLDGYAE KGGHHLNVNV LNRETLLDAQ AHPEKYPQLT IRVSGYAVNF IKLTKEQQDD VITRTFHASL Position: 10 20 30 40 50 60 70
Sequence: MKIAIAQAE IIFEQPEENL ANAAAWIAQA AAAQADCIVF PEMSFTGFSM QVEKIAGYAP KIHEKMRQLA VQCGIAIGYG WTSKKQHGKG ENHYTLLDKN GGVLSDYVKI HPFSYGGEDR FYHSGEKLTS AVLGEFSVGT LICYDLRFPE VFRAAAQKNR LLLVPANWLH QRTAHWRILL RARAIENQVY VLGVNCVGRQ QSYTFDGQSC LVNPEGELLC TCGGEKQLVY VTIADDTEQF RQAFPTCRDV KISLYRKLYE DIF
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260
PF00795: 1-240 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌
Sequence: MKIAIAQAE IIFEQPEENL ANAAAWIAQA AAAQADCIVF PEMSFTGFSM QVEKIAGYAP KIHEKMRQLA VQCGIAIGYG WTSKKQHGKG ENHYTLLDKN GGVLSDYVKI HPFSYGGEDR FYHSGEKLTS AVLGEFSVGT LICYDLRFPE VFRAAAQKNR LLLVPANWLH QRTAHWRILL RARAIENQVY VLGVNCVGRQ QSYTFDGQSC LVNPEGELLC TCGGEKQLVY VTIADDTEQF RQAFPTCRDV KISLYRKLYE DIF HMM: 407-441 ALI: 57-92 AP KIHEKMRQLA VQCGIAIGYG WTSKKQHGKG ENHY ENV: 48-99 M QVEKIAGYAP KIHEKMRQLA VQCGIAIGYG WTSKKQHGKG ENHYTLLDKN G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260
Sequence: MHKNLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQV YHRRDAIYPA TIVANRARKT ITSENGCRN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
PF01977: 8-314 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MHKNLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQV YHRRDAIYPA TIVANRARKT ITSENGCRN HMM: 1-297 HKNLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQ ALI: 1-309 HKNLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQV YHRRDAIYPA T ENV: 1-320 HKNLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQV YHRRDAIYPA TIVANRARKT IT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
Sequence: MHKNLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQV YHRRDAIYPA TIVANRARKT ITSENGCRN HMM: 4-314 LRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQV YHRRDAIYPA TIVANR ALI: 3-314 NLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQV YHRRDAIYPA TIVANR ENV: 1-320 HKNLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQV YHRRDAIYPA TIVANRARKT IT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
Sequence: MHKNLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQV YHRRDAIYPA TIVANRARKT ITSENGCRN HMM: 3-297 NLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQ ALI: 2-308 KNLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQV YHRRDAIYPA ENV: 1-317 HKNLRSFI DQLKKEKEII EVNAEVDPYL ELAEIHRRIV DEGGPALLFT RVKGSRFPAA TNLFGTVRRV EMAIGPKPEE TINRAVKALD KLMPPSLKAL WGERDWLFSL AKVGQRDIAK NKAPVLARRM PKVNLHELPV LTSWQEDGGP FFTLPLVYTE HPLKKEHNLG MYRLQVFSEN QTGMHWQIHK GGGFHYYEAE KQGQSLPVTV FLGGPPALVI AAITALPEPV PELLYASFLS GDKIDMVEVE NHPHKLIAEA EFALCGEVPP HVRKPEGPFG DHYGYYSLVH DFPVFNIKQV YHRRDAIYPA TIVANRARK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
Sequence: MQELISPLF PLLMPGLKSL WSYAETGFHS LSGAIVRESY HREALAHAFR ILGEGQLSLT KVLLLTDVDL DLKDFPRLLE TILQRFNPAR DLIIINDTAM DTLDYTGRKF NQGSKAVMLG LGNPIRDLPR GYIGESLPGI TRVKPYCGGC LLISGTDYTS APELGNEIIQ QNLTSLREWP LVILVDNADS IIDQTSFLWT VFTRFDPAFD IYAAHRYITI RSNMKARF
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220
PF01977: 1-97 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
Sequence: MQELISPLF PLLMPGLKSL WSYAETGFHS LSGAIVRESY HREALAHAFR ILGEGQLSLT KVLLLTDVDL DLKDFPRLLE TILQRFNPAR DLIIINDTAM DTLDYTGRKF NQGSKAVMLG LGNPIRDLPR GYIGESLPGI TRVKPYCGGC LLISGTDYTS APELGNEIIQ QNLTSLREWP LVILVDNADS IIDQTSFLWT VFTRFDPAFD IYAAHRYITI RSNMKARF HMM: 332-440 ALI: 7-115 LF PLLMPGLKSL WSYAETGFHS LSGAIVRESY HREALAHAFR ILGEGQLSLT KVLLLTDVDL DLKDFPRLLE TILQRFNPAR DLIIINDTAM DTLDYTGRKF NQGSKAV ENV: 2-129 ELISPLF PLLMPGLKSL WSYAETGFHS LSGAIVRESY HREALAHAFR ILGEGQLSLT KVLLLTDVDL DLKDFPRLLE TILQRFNPAR DLIIINDTAM DTLDYTGRKF NQGSKAVMLG LGNPIRDLPR G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220
Sequence: MQELISPLF PLLMPGLKSL WSYAETGFHS LSGAIVRESY HREALAHAFR ILGEGQLSLT KVLLLTDVDL DLKDFPRLLE TILQRFNPAR DLIIINDTAM DTLDYTGRKF NQGSKAVMLG LGNPIRDLPR GYIGESLPGI TRVKPYCGGC LLISGTDYTS APELGNEIIQ QNLTSLREWP LVILVDNADS IIDQTSFLWT VFTRFDPAFD IYAAHRYITI RSNMKARF HMM: 386-416 ALI: 180-210 VILVDNADS IIDQTSFLWT VFTRFDPAFD IY ENV: 165-215 EIIQ QNLTSLREWP LVILVDNADS IIDQTSFLWT VFTRFDPAFD IYAAHRY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
PF00384: 3-333 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF01568: 414-523 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 250-313 MMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAV ALI: 32-95 IKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTE ENV: 12-97 QLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 389-470 FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RR ALI: 100-183 MAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNV ENV: 95-193 EGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 610-696 ALI: 262-346 ALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIF ENV: 256-366 IHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 838-918 ALI: 412-493 YPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFH ENV: 400-498 EFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 249-311 PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRK ALI: 34-96 SNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEG ENV: 11-99 AQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE E Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 392-462 GLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGD ALI: 105-175 AKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVN ENV: 97-213 YE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 610-680 ALI: 265-333 NLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRL ENV: 232-343 AKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 820-900 ALI: 411-492 EYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYF ENV: 400-506 EFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNAS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 246-330 GEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LS ALI: 11-96 AQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEG ENV: 3-98 SINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 406-481 ELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITA ALI: 102-177 AVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPL ENV: 96-190 GYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 586-710 ALI: 225-345 LTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEI ENV: 195-367 TYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSINELQ NDAQLVFLIG TNTTENHPVI GYKIKSNVRK NGAKLIVADP RSIDLSNMAD VFIQFKPGTD VALINGMMNV IIEEGLADKE FIANRTEGYE EMAAVVAKYT PEAVEKITGV AAEDIRMAAR LYASAERASI CYAMGLTQHS TGTDNVKSIC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVTYPA YQKVVDDAVR EKFEKAWGVK LSPNNGLTIT AAIAKAHHGE LKGLIVIGEN PMMSDPDIHH VEEALDNLDF LMVQDIFLTE TAQKADVVFP GVSFAEKDGT FTNTERRVQR VRKAVNPRGD ARPDWQIICE LSNRLGYSMN YNSVEEIFEE IRTVTPSYAG MTYQRLEGKG LQWPCPSEDH AGTPVLHKEK FNRGLGLFHA IEFKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANVLTNASPE SLDPVAGIPE YKVAAARVEK I HMM: 841-922 ALI: 412-494 YPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHF ENV: 401-501 FKEAAELP DEEYPLILTT GRSLYHYHTG TMTRRAIALD AIQPENEVQI SPVTAANLGI NDGDMVRVIT RRGKIDVKAR ITAAVSENVI FTYFHFAEAA ANV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MSLGRVSAF LDIYIERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP FLEFCAELSI QTCALQYEND DLMRDYYGDD YAIACCVSAM RLGKETQLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLHYYMA FGLAGLSVTA DSLSAIRYGR VKVIKDERGL AAAFQSEGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK F
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
PF02901: 0-339 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
PF01228: 355-461 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MSLGRVSAF LDIYIERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP FLEFCAELSI QTCALQYEND DLMRDYYGDD YAIACCVSAM RLGKETQLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLHYYMA FGLAGLSVTA DSLSAIRYGR VKVIKDERGL AAAFQSEGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK F HMM: 633-817 ALI: 289-475 PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTF ENV: 274-478 DERGL AAAFQSEGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MSLGRVSAF LDIYIERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP FLEFCAELSI QTCALQYEND DLMRDYYGDD YAIACCVSAM RLGKETQLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLHYYMA FGLAGLSVTA DSLSAIRYGR VKVIKDERGL AAAFQSEGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK F HMM: 491-552 ALI: 170-231 AINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAY ENV: 155-244 QLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MSLGRVSAF LDIYIERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP FLEFCAELSI QTCALQYEND DLMRDYYGDD YAIACCVSAM RLGKETQLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLHYYMA FGLAGLSVTA DSLSAIRYGR VKVIKDERGL AAAFQSEGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK F HMM: 329-428 LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN ALI: 13-112 IERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP FLEF ENV: 5-129 VSAF LDIYIERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP FLEFCAELSI QTCALQYEND D Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MSLGRVSAF LDIYIERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP FLEFCAELSI QTCALQYEND DLMRDYYGDD YAIACCVSAM RLGKETQLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLHYYMA FGLAGLSVTA DSLSAIRYGR VKVIKDERGL AAAFQSEGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK F HMM: 490-562 ALI: 159-232 ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYE ENV: 140-245 AIACCVSAM RLGKETQLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLHY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MSLGRVSAF LDIYIERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP FLEFCAELSI QTCALQYEND DLMRDYYGDD YAIACCVSAM RLGKETQLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLHYYMA FGLAGLSVTA DSLSAIRYGR VKVIKDERGL AAAFQSEGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK F HMM: 645-830 ALI: 290-476 CFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFY ENV: 285-478 EGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MSLGRVSAF LDIYIERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP FLEFCAELSI QTCALQYEND DLMRDYYGDD YAIACCVSAM RLGKETQLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLHYYMA FGLAGLSVTA DSLSAIRYGR VKVIKDERGL AAAFQSEGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK F HMM: 351-431 GEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLD ALI: 23-104 NEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQR ENV: 11-108 IYIERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MSLGRVSAF LDIYIERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP FLEFCAELSI QTCALQYEND DLMRDYYGDD YAIACCVSAM RLGKETQLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLHYYMA FGLAGLSVTA DSLSAIRYGR VKVIKDERGL AAAFQSEGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK F HMM: 509-588 ALI: 159-238 ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL ENV: 128-253 D DLMRDYYGDD YAIACCVSAM RLGKETQLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLHYYMA FGLAG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MSLGRVSAF LDIYIERDLQ QGRINEERAQ ELIDQLVIKL RLVRHLRTPE YNELFAGDPN WVTESLGGMG TDGRPLVTKS SFRFLNTLRN LGPSPEPNMT ILWSQRLPRP FLEFCAELSI QTCALQYEND DLMRDYYGDD YAIACCVSAM RLGKETQLFG ARCNLAKLLL YAINGGRDEI TGEQVGVEMP VYEEEYLDYQ QVMHRLQVQM EWLTRLYVNT MNVIHFMHDR YAYESLQMAL HDSKLHYYMA FGLAGLSVTA DSLSAIRYGR VKVIKDERGL AAAFQSEGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK F HMM: 663-846 ALI: 290-475 CFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTF ENV: 280-479 AAFQSEGDF PCFGNDDDRV DSIAVQLIKD FSCSLQKHTA YRNAQHTLSI LTITSNVMYG KHTGDTPDGR KRGEALAPGA NPVHGREKMG ALAGLNSLAK LPYSYARDGI SLTFSIVPES LGKSEIEKIN NLLALLQGYF SQGAHHMNVN VLDPETLIKA MQHPEEYADL TIRVSGYAVH FTKLSRELQE EIIARTFYRK F Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MSSRITRRQ FITRGGATVA SLGLAASLGF DLEATASEVK GLRIVNITPT PTVCPYCGSG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL FSGYDPATRK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPGYVESPT VTPEHKDLLA FIRKVTPGAD KVNFTSLEEL RPLVKEGFPN SGWRIHSSKW VVSMLKAWYG KAAVPENDFA FHYLPKRDPK KNYSHIGMFE AMHRGEIEGL FVNGTNPVVG GPNANKEQEA LCNLKWMVAI DLWLTETADF WTYQGWERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG ASGDEPDVLK VANELCGYNV ADGTPVEGFA KLADDGSTAC GCWVYCGATT LKDGKFVYKT QLRQHEDPSG LGLFPNWSWA WPMNRRIVYN RCSVQPDGIT PWPGDAERQL VRWDPLAIPD PKKPEVVGSW VGVDVPDMIK TTGPDKPAFI NPFIMRTDGK GALFAIKTLM KDGPFPEHYE PWESPLEPIL NKQALNPAAN IWEPDKQGKT DKYPIIGTSF RLVEHWQTGA LTRNLPWLAE LMPNMFVELS EQLAKEKGIK NGGKVIVSTS RGDIEAIACV TKRLKPFNLN GKTVHEIGMP WQFGFKGYAT GDPCNRLTPH IGDANTVCPE YKAWLCDIRR A
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070
PF04879: 48-102 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF00384: 119-628 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF01568: 946-1063 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MSSRITRRQ FITRGGATVA SLGLAASLGF DLEATASEVK GLRIVNITPT PTVCPYCGSG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL FSGYDPATRK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPGYVESPT VTPEHKDLLA FIRKVTPGAD KVNFTSLEEL RPLVKEGFPN SGWRIHSSKW VVSMLKAWYG KAAVPENDFA FHYLPKRDPK KNYSHIGMFE AMHRGEIEGL FVNGTNPVVG GPNANKEQEA LCNLKWMVAI DLWLTETADF WTYQGWERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG ASGDEPDVLK VANELCGYNV ADGTPVEGFA KLADDGSTAC GCWVYCGATT LKDGKFVYKT QLRQHEDPSG LGLFPNWSWA WPMNRRIVYN RCSVQPDGIT PWPGDAERQL VRWDPLAIPD PKKPEVVGSW VGVDVPDMIK TTGPDKPAFI NPFIMRTDGK GALFAIKTLM KDGPFPEHYE PWESPLEPIL NKQALNPAAN IWEPDKQGKT DKYPIIGTSF RLVEHWQTGA LTRNLPWLAE LMPNMFVELS EQLAKEKGIK NGGKVIVSTS RGDIEAIACV TKRLKPFNLN GKTVHEIGMP WQFGFKGYAT GDPCNRLTPH IGDANTVCPE YKAWLCDIRR A HMM: 3-30 RITRRQ FITRGGATVA SLGLAASLGF DL ALI: 2-30 SRITRRQ FITRGGATVA SLGLAASLGF DL ENV: 1-42 SSRITRRQ FITRGGATVA SLGLAASLGF DLEATASEVK GLRI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070
Sequence: MSSRITRRQ FITRGGATVA SLGLAASLGF DLEATASEVK GLRIVNITPT PTVCPYCGSG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL FSGYDPATRK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPGYVESPT VTPEHKDLLA FIRKVTPGAD KVNFTSLEEL RPLVKEGFPN SGWRIHSSKW VVSMLKAWYG KAAVPENDFA FHYLPKRDPK KNYSHIGMFE AMHRGEIEGL FVNGTNPVVG GPNANKEQEA LCNLKWMVAI DLWLTETADF WTYQGWERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG ASGDEPDVLK VANELCGYNV ADGTPVEGFA KLADDGSTAC GCWVYCGATT LKDGKFVYKT QLRQHEDPSG LGLFPNWSWA WPMNRRIVYN RCSVQPDGIT PWPGDAERQL VRWDPLAIPD PKKPEVVGSW VGVDVPDMIK TTGPDKPAFI NPFIMRTDGK GALFAIKTLM KDGPFPEHYE PWESPLEPIL NKQALNPAAN IWEPDKQGKT DKYPIIGTSF RLVEHWQTGA LTRNLPWLAE LMPNMFVELS EQLAKEKGIK NGGKVIVSTS RGDIEAIACV TKRLKPFNLN GKTVHEIGMP WQFGFKGYAT GDPCNRLTPH IGDANTVCPE YKAWLCDIRR A HMM: 120-321 IQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNY ALI: 114-331 EINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDE ENV: 57-339 SG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL F Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070
Sequence: MSSRITRRQ FITRGGATVA SLGLAASLGF DLEATASEVK GLRIVNITPT PTVCPYCGSG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL FSGYDPATRK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPGYVESPT VTPEHKDLLA FIRKVTPGAD KVNFTSLEEL RPLVKEGFPN SGWRIHSSKW VVSMLKAWYG KAAVPENDFA FHYLPKRDPK KNYSHIGMFE AMHRGEIEGL FVNGTNPVVG GPNANKEQEA LCNLKWMVAI DLWLTETADF WTYQGWERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG ASGDEPDVLK VANELCGYNV ADGTPVEGFA KLADDGSTAC GCWVYCGATT LKDGKFVYKT QLRQHEDPSG LGLFPNWSWA WPMNRRIVYN RCSVQPDGIT PWPGDAERQL VRWDPLAIPD PKKPEVVGSW VGVDVPDMIK TTGPDKPAFI NPFIMRTDGK GALFAIKTLM KDGPFPEHYE PWESPLEPIL NKQALNPAAN IWEPDKQGKT DKYPIIGTSF RLVEHWQTGA LTRNLPWLAE LMPNMFVELS EQLAKEKGIK NGGKVIVSTS RGDIEAIACV TKRLKPFNLN GKTVHEIGMP WQFGFKGYAT GDPCNRLTPH IGDANTVCPE YKAWLCDIRR A HMM: 383-471 HYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GAT ALI: 374-468 HCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ ENV: 359-508 DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPGYVESPT VTPEHKDLLA FIRKVTPGAD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070
Sequence: MSSRITRRQ FITRGGATVA SLGLAASLGF DLEATASEVK GLRIVNITPT PTVCPYCGSG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL FSGYDPATRK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPGYVESPT VTPEHKDLLA FIRKVTPGAD KVNFTSLEEL RPLVKEGFPN SGWRIHSSKW VVSMLKAWYG KAAVPENDFA FHYLPKRDPK KNYSHIGMFE AMHRGEIEGL FVNGTNPVVG GPNANKEQEA LCNLKWMVAI DLWLTETADF WTYQGWERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG ASGDEPDVLK VANELCGYNV ADGTPVEGFA KLADDGSTAC GCWVYCGATT LKDGKFVYKT QLRQHEDPSG LGLFPNWSWA WPMNRRIVYN RCSVQPDGIT PWPGDAERQL VRWDPLAIPD PKKPEVVGSW VGVDVPDMIK TTGPDKPAFI NPFIMRTDGK GALFAIKTLM KDGPFPEHYE PWESPLEPIL NKQALNPAAN IWEPDKQGKT DKYPIIGTSF RLVEHWQTGA LTRNLPWLAE LMPNMFVELS EQLAKEKGIK NGGKVIVSTS RGDIEAIACV TKRLKPFNLN GKTVHEIGMP WQFGFKGYAT GDPCNRLTPH IGDANTVCPE YKAWLCDIRR A HMM: 634-688 WERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ALI: 657-709 FL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY A ENV: 645-730 KKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG AS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070
Sequence: MSSRITRRQ FITRGGATVA SLGLAASLGF DLEATASEVK GLRIVNITPT PTVCPYCGSG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL FSGYDPATRK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPGYVESPT VTPEHKDLLA FIRKVTPGAD KVNFTSLEEL RPLVKEGFPN SGWRIHSSKW VVSMLKAWYG KAAVPENDFA FHYLPKRDPK KNYSHIGMFE AMHRGEIEGL FVNGTNPVVG GPNANKEQEA LCNLKWMVAI DLWLTETADF WTYQGWERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG ASGDEPDVLK VANELCGYNV ADGTPVEGFA KLADDGSTAC GCWVYCGATT LKDGKFVYKT QLRQHEDPSG LGLFPNWSWA WPMNRRIVYN RCSVQPDGIT PWPGDAERQL VRWDPLAIPD PKKPEVVGSW VGVDVPDMIK TTGPDKPAFI NPFIMRTDGK GALFAIKTLM KDGPFPEHYE PWESPLEPIL NKQALNPAAN IWEPDKQGKT DKYPIIGTSF RLVEHWQTGA LTRNLPWLAE LMPNMFVELS EQLAKEKGIK NGGKVIVSTS RGDIEAIACV TKRLKPFNLN GKTVHEIGMP WQFGFKGYAT GDPCNRLTPH IGDANTVCPE YKAWLCDIRR A HMM: 116-319 NPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV V ALI: 113-332 QEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEY ENV: 99-464 MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL FSGYDPATRK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070
Sequence: MSSRITRRQ FITRGGATVA SLGLAASLGF DLEATASEVK GLRIVNITPT PTVCPYCGSG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL FSGYDPATRK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPGYVESPT VTPEHKDLLA FIRKVTPGAD KVNFTSLEEL RPLVKEGFPN SGWRIHSSKW VVSMLKAWYG KAAVPENDFA FHYLPKRDPK KNYSHIGMFE AMHRGEIEGL FVNGTNPVVG GPNANKEQEA LCNLKWMVAI DLWLTETADF WTYQGWERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG ASGDEPDVLK VANELCGYNV ADGTPVEGFA KLADDGSTAC GCWVYCGATT LKDGKFVYKT QLRQHEDPSG LGLFPNWSWA WPMNRRIVYN RCSVQPDGIT PWPGDAERQL VRWDPLAIPD PKKPEVVGSW VGVDVPDMIK TTGPDKPAFI NPFIMRTDGK GALFAIKTLM KDGPFPEHYE PWESPLEPIL NKQALNPAAN IWEPDKQGKT DKYPIIGTSF RLVEHWQTGA LTRNLPWLAE LMPNMFVELS EQLAKEKGIK NGGKVIVSTS RGDIEAIACV TKRLKPFNLN GKTVHEIGMP WQFGFKGYAT GDPCNRLTPH IGDANTVCPE YKAWLCDIRR A HMM: 631-681 YQGWERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRW ALI: 657-705 FL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIK ENV: 650-709 DIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070
Sequence: MSSRITRRQ FITRGGATVA SLGLAASLGF DLEATASEVK GLRIVNITPT PTVCPYCGSG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL FSGYDPATRK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPGYVESPT VTPEHKDLLA FIRKVTPGAD KVNFTSLEEL RPLVKEGFPN SGWRIHSSKW VVSMLKAWYG KAAVPENDFA FHYLPKRDPK KNYSHIGMFE AMHRGEIEGL FVNGTNPVVG GPNANKEQEA LCNLKWMVAI DLWLTETADF WTYQGWERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG ASGDEPDVLK VANELCGYNV ADGTPVEGFA KLADDGSTAC GCWVYCGATT LKDGKFVYKT QLRQHEDPSG LGLFPNWSWA WPMNRRIVYN RCSVQPDGIT PWPGDAERQL VRWDPLAIPD PKKPEVVGSW VGVDVPDMIK TTGPDKPAFI NPFIMRTDGK GALFAIKTLM KDGPFPEHYE PWESPLEPIL NKQALNPAAN IWEPDKQGKT DKYPIIGTSF RLVEHWQTGA LTRNLPWLAE LMPNMFVELS EQLAKEKGIK NGGKVIVSTS RGDIEAIACV TKRLKPFNLN GKTVHEIGMP WQFGFKGYAT GDPCNRLTPH IGDANTVCPE YKAWLCDIRR A HMM: 126-338 RAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL ALI: 93-332 CAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEY ENV: 56-339 GSG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL F Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070
Sequence: MSSRITRRQ FITRGGATVA SLGLAASLGF DLEATASEVK GLRIVNITPT PTVCPYCGSG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL FSGYDPATRK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPGYVESPT VTPEHKDLLA FIRKVTPGAD KVNFTSLEEL RPLVKEGFPN SGWRIHSSKW VVSMLKAWYG KAAVPENDFA FHYLPKRDPK KNYSHIGMFE AMHRGEIEGL FVNGTNPVVG GPNANKEQEA LCNLKWMVAI DLWLTETADF WTYQGWERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG ASGDEPDVLK VANELCGYNV ADGTPVEGFA KLADDGSTAC GCWVYCGATT LKDGKFVYKT QLRQHEDPSG LGLFPNWSWA WPMNRRIVYN RCSVQPDGIT PWPGDAERQL VRWDPLAIPD PKKPEVVGSW VGVDVPDMIK TTGPDKPAFI NPFIMRTDGK GALFAIKTLM KDGPFPEHYE PWESPLEPIL NKQALNPAAN IWEPDKQGKT DKYPIIGTSF RLVEHWQTGA LTRNLPWLAE LMPNMFVELS EQLAKEKGIK NGGKVIVSTS RGDIEAIACV TKRLKPFNLN GKTVHEIGMP WQFGFKGYAT GDPCNRLTPH IGDANTVCPE YKAWLCDIRR A HMM: 399-482 PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPG ALI: 375-462 CVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALR ENV: 347-474 RK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070
Sequence: MSSRITRRQ FITRGGATVA SLGLAASLGF DLEATASEVK GLRIVNITPT PTVCPYCGSG CGLVVYAQKD ANGKFQKLLS VHGDPDNPIN QGGACAKGAA MFNLREIYNE ETGEQEINPK RIQKPLYRAP GSDKWEEKDW DWMLDRIAER VKETRDSSFV HKKKLEDGSE IIVNHTEKIA SIGGSGMDNE ECYLLSKLMR SLGVVYLETQ ARLCHSPSVG GLAPSFGRGV MTNHVVDMKN TDCALIMGSN CAENHPITMK WLLKARETRG AKLISVDPRF TRTAARADIY APMRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLV KDEYDFRDGL FSGYDPATRK YDVSSWDYKY DEKNLPLTDP TLQDPHCVFQ LMKKHYQRYD IDTVCSITGT PKNKYLEVLD TFCATGKPNK TGTILYAMGI TQHTVGSQNI RAFAIVQLLL GNIGRPGGGI NALRGENNVQ GATDMGLLFN NIPGYVESPT VTPEHKDLLA FIRKVTPGAD KVNFTSLEEL RPLVKEGFPN SGWRIHSSKW VVSMLKAWYG KAAVPENDFA FHYLPKRDPK KNYSHIGMFE AMHRGEIEGL FVNGTNPVVG GPNANKEQEA LCNLKWMVAI DLWLTETADF WTYQGWERPV DNPNVPKKTP ADIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG ASGDEPDVLK VANELCGYNV ADGTPVEGFA KLADDGSTAC GCWVYCGATT LKDGKFVYKT QLRQHEDPSG LGLFPNWSWA WPMNRRIVYN RCSVQPDGIT PWPGDAERQL VRWDPLAIPD PKKPEVVGSW VGVDVPDMIK TTGPDKPAFI NPFIMRTDGK GALFAIKTLM KDGPFPEHYE PWESPLEPIL NKQALNPAAN IWEPDKQGKT DKYPIIGTSF RLVEHWQTGA LTRNLPWLAE LMPNMFVELS EQLAKEKGIK NGGKVIVSTS RGDIEAIACV TKRLKPFNLN GKTVHEIGMP WQFGFKGYAT GDPCNRLTPH IGDANTVCPE YKAWLCDIRR A HMM: 650-708 DIKTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY ALI: 658-714 L PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLP ENV: 652-729 KTEVFFL PACAVYEKEG TAASTGRWVQ YRWKGADPVG ESKADLWTYN QLAKKIKAVY AGSKLPQDEP ILNMTWDYDG A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850 860 870 880 890 900 910 920 930 940 950 960 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070
Sequence: MSPSFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTSKW VVSLLKAWWG DAAKPENDFA YHYLPKRDEK KNYSHIAIFE AMYKGEIDGL FVSGSNPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPEDEP IVNMTWDYEG PAGSEEPDIM KVARELCGYD TKTKAPIEGF AKLTDDGATA CGCWVYCGAM TTLPDGTVQY KPQKRDNVDN SKTGLGLFSN WAWCWPMNRR IVYNRCSVQP DGITPWPGDA ERSWYTGIPW HCLILRSQNC WAAGSETMCP TS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
PF00384: 8-409 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
Sequence: MSPSFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTSKW VVSLLKAWWG DAAKPENDFA YHYLPKRDEK KNYSHIAIFE AMYKGEIDGL FVSGSNPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPEDEP IVNMTWDYEG PAGSEEPDIM KVARELCGYD TKTKAPIEGF AKLTDDGATA CGCWVYCGAM TTLPDGTVQY KPQKRDNVDN SKTGLGLFSN WAWCWPMNRR IVYNRCSVQP DGITPWPGDA ERSWYTGIPW HCLILRSQNC WAAGSETMCP TS HMM: 216-319 QNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTSKW V ALI: 5-109 GRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI D ENV: 2-118 PSFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MSPSFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTSKW VVSLLKAWWG DAAKPENDFA YHYLPKRDEK KNYSHIAIFE AMYKGEIDGL FVSGSNPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPEDEP IVNMTWDYEG PAGSEEPDIM KVARELCGYD TKTKAPIEGF AKLTDDGATA CGCWVYCGAM TTLPDGTVQY KPQKRDNVDN SKTGLGLFSN WAWCWPMNRR IVYNRCSVQP DGITPWPGDA ERSWYTGIPW HCLILRSQNC WAAGSETMCP TS HMM: 374-469 NPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG E ALI: 145-243 LTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRG ENV: 132-270 TTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MSPSFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTSKW VVSLLKAWWG DAAKPENDFA YHYLPKRDEK KNYSHIAIFE AMYKGEIDGL FVSGSNPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPEDEP IVNMTWDYEG PAGSEEPDIM KVARELCGYD TKTKAPIEGF AKLTDDGATA CGCWVYCGAM TTLPDGTVQY KPQKRDNVDN SKTGLGLFSN WAWCWPMNRR IVYNRCSVQP DGITPWPGDA ERSWYTGIPW HCLILRSQNC WAAGSETMCP TS HMM: 634-687 RSQNC WAAGSETMCP TS ALI: 437-488 FL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY ENV: 424-509 PKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPEDEP IVNMTWDYEG P Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MSPSFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTSKW VVSLLKAWWG DAAKPENDFA YHYLPKRDEK KNYSHIAIFE AMYKGEIDGL FVSGSNPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPEDEP IVNMTWDYEG PAGSEEPDIM KVARELCGYD TKTKAPIEGF AKLTDDGATA CGCWVYCGAM TTLPDGTVQY KPQKRDNVDN SKTGLGLFSN WAWCWPMNRR IVYNRCSVQP DGITPWPGDA ERSWYTGIPW HCLILRSQNC WAAGSETMCP TS HMM: 224-316 VQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTS ALI: 16-109 MKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI D ENV: 3-142 SFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MSPSFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTSKW VVSLLKAWWG DAAKPENDFA YHYLPKRDEK KNYSHIAIFE AMYKGEIDGL FVSGSNPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPEDEP IVNMTWDYEG PAGSEEPDIM KVARELCGYD TKTKAPIEGF AKLTDDGATA CGCWVYCGAM TTLPDGTVQY KPQKRDNVDN SKTGLGLFSN WAWCWPMNRR IVYNRCSVQP DGITPWPGDA ERSWYTGIPW HCLILRSQNC WAAGSETMCP TS HMM: 373-465 SNPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGAD ALI: 146-242 TDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMR ENV: 135-255 DYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMAL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MSPSFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTSKW VVSLLKAWWG DAAKPENDFA YHYLPKRDEK KNYSHIAIFE AMYKGEIDGL FVSGSNPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPEDEP IVNMTWDYEG PAGSEEPDIM KVARELCGYD TKTKAPIEGF AKLTDDGATA CGCWVYCGAM TTLPDGTVQY KPQKRDNVDN SKTGLGLFSN WAWCWPMNRR IVYNRCSVQP DGITPWPGDA ERSWYTGIPW HCLILRSQNC WAAGSETMCP TS HMM: 631-683 LILRSQNC WAAGSETMCP TS ALI: 437-487 FL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKA ENV: 390-504 CNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPEDEP IVNMTW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MSPSFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTSKW VVSLLKAWWG DAAKPENDFA YHYLPKRDEK KNYSHIAIFE AMYKGEIDGL FVSGSNPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPEDEP IVNMTWDYEG PAGSEEPDIM KVARELCGYD TKTKAPIEGF AKLTDDGATA CGCWVYCGAM TTLPDGTVQY KPQKRDNVDN SKTGLGLFSN WAWCWPMNRR IVYNRCSVQP DGITPWPGDA ERSWYTGIPW HCLILRSQNC WAAGSETMCP TS HMM: 244-482 ENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTSKW VVSLLKAWWG DAAKPENDFA YHYLPKRDEK KNYSHIAIFE AMYKGEIDGL FVSGSNPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGK ALI: 17-242 KN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMR ENV: 3-256 SFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MSPSFGRGV MTNHIVDMKN TDCALIMGSN VAENHPISMK WLFKAKENRG AKLIHVDPRF TRTSARADIY APLRSGTDIA FLGGMIKYIL DNELYHKDYV VNYTNAAFLI DDKYGFEDGL FTGYDPANRK YDPTTWDYKK DDKGAALTDP TLQDPRCVFQ LMKKHYERYD IDTVCKITGT PKDKYLEVLK TFCATGKPNK VGTIIYAMGI TQHTVGAQNI RAFAIVQLLL GNMGRPGGGI NAMRGENNVQ GATDMALLFH YIPGYIDSPM NSTANKDLIS YLKAVTPGAA KLPVTNLEEL RAAVKEGFPN SGFKINTSKW VVSLLKAWWG DAAKPENDFA YHYLPKRDEK KNYSHIAIFE AMYKGEIDGL FVSGSNPVVG GPNANKEQEA MCNLKWMVSS DLWLNETAEF WTYQAWERPV DNPNVPKKTP ADIQTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPEDEP IVNMTWDYEG PAGSEEPDIM KVARELCGYD TKTKAPIEGF AKLTDDGATA CGCWVYCGAM TTLPDGTVQY KPQKRDNVDN SKTGLGLFSN WAWCWPMNRR IVYNRCSVQP DGITPWPGDA ERSWYTGIPW HCLILRSQNC WAAGSETMCP TS HMM: 650-701 S ALI: 438-487 L PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKA ENV: 432-495 QTEVFFL PAAAVYEKEG TAAQTGRWVQ YRWKGADPVG ESKADLAIIY ELGKAIKKAY AGSKRPE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MKVTRRQFL KVTGATAASF AVLDLGFDMQ ATAAGVKELR IKNVTPTPTV CPYCASGCGL VVYSEKDSAG KFVKLLSVHG DPDNPINQGG ACAKGAAMFN LREIYNEETG EQEINPKRVQ KPMYRAPGSD KWEEKDWEWM VETIAQRVKE TRDKSFIHKE KNADGNEVIV NRTERIAHVG GSGLDNEEAY ILSKLMRSLG LVYLETQARI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
PF04879: 45-99 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MKVTRRQFL KVTGATAASF AVLDLGFDMQ ATAAGVKELR IKNVTPTPTV CPYCASGCGL VVYSEKDSAG KFVKLLSVHG DPDNPINQGG ACAKGAAMFN LREIYNEETG EQEINPKRVQ KPMYRAPGSD KWEEKDWEWM VETIAQRVKE TRDKSFIHKE KNADGNEVIV NRTERIAHVG GSGLDNEEAY ILSKLMRSLG LVYLETQARI HMM: 5-200 RQFL KVTGATAASF AVLDLGFDMQ ATAAGVKELR IKNVTPTPTV CPYCASGCGL VVYSEKDSAG KFVKLLSVHG DPDNPINQGG ACAKGAAMFN LREIYNEETG EQEINPKRVQ KPMYRAPGSD KWEEKDWEWM VETIAQRVKE TRDKSFIHKE KNADGNEVIV NRTERIAHVG GSGLDNEEAY ILSKLMRSLG LV ALI: 2-184 VTRRQFL KVTGATAASF AVLDLGFDMQ ATAAGVKELR IKNVTPTPTV CPYCASGCGL VVYSEKDSAG KFVKLLSVHG DPDNPINQGG ACAKGAAMFN LREIYNEETG EQEINPKRVQ KPMYRAPGSD KWEEKDWEWM VETIAQRVKE TRDKSFIHKE KNADGNEVIV NRTERIAHVG GSGLDN ENV: 1-203 KVTRRQFL KVTGATAASF AVLDLGFDMQ ATAAGVKELR IKNVTPTPTV CPYCASGCGL VVYSEKDSAG KFVKLLSVHG DPDNPINQGG ACAKGAAMFN LREIYNEETG EQEINPKRVQ KPMYRAPGSD KWEEKDWEWM VETIAQRVKE TRDKSFIHKE KNADGNEVIV NRTERIAHVG GSGLDNEEAY ILSKLMRSLG LVYLE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MSKYETEVD IVVVGAGVIG LAAAVELAHR NPAAQILLIE KNRGYGQEVS SRSSEVIHAG LYYPPGSLKA RFCAEGNRLL YEFCTQYRIP HRCTGKLVTA TVAEEAVDLQ KLYQKAISNG VEVDYLEAGQ VKIMEPHVQA VAALFSPTTG IIDSHRFMYA LFYKARQNGV TVLFNSPLHN IEVLANSYIL VFARERIKSR VVINCAGLHS DVVAAMAGLD IDETGYRLHY CRGEYYRLRR RYEFAHLVYP LPEKNGLGIH LTLDLQGGQR LGPDTRYVDT IDYSIDDSYK EKFYFAARRY LPWLEMEDLQ PDYAGIRPKL QTEGGEFRDF VINEESCHGL PGFINLIGIE SPGLTAALAI ARYAAKLVEN MFN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF01266: 8-366 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
Sequence: MSKYETEVD IVVVGAGVIG LAAAVELAHR NPAAQILLIE KNRGYGQEVS SRSSEVIHAG LYYPPGSLKA RFCAEGNRLL YEFCTQYRIP HRCTGKLVTA TVAEEAVDLQ KLYQKAISNG VEVDYLEAGQ VKIMEPHVQA VAALFSPTTG IIDSHRFMYA LFYKARQNGV TVLFNSPLHN IEVLANSYIL VFARERIKSR VVINCAGLHS DVVAAMAGLD IDETGYRLHY CRGEYYRLRR RYEFAHLVYP LPEKNGLGIH LTLDLQGGQR LGPDTRYVDT IDYSIDDSYK EKFYFAARRY LPWLEMEDLQ PDYAGIRPKL QTEGGEFRDF VINEESCHGL PGFINLIGIE SPGLTAALAI ARYAAKLVEN MFN HMM: 4-41 ETEVD IVVVGAGVIG LAAAVELAHR NPAAQILLIE KNR ALI: 6-43 EVD IVVVGAGVIG LAAAVELAHR NPAAQILLIE KNRGY ENV: 2-48 KYETEVD IVVVGAGVIG LAAAVELAHR NPAAQILLIE KNRGYGQEVS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MSKYETEVD IVVVGAGVIG LAAAVELAHR NPAAQILLIE KNRGYGQEVS SRSSEVIHAG LYYPPGSLKA RFCAEGNRLL YEFCTQYRIP HRCTGKLVTA TVAEEAVDLQ KLYQKAISNG VEVDYLEAGQ VKIMEPHVQA VAALFSPTTG IIDSHRFMYA LFYKARQNGV TVLFNSPLHN IEVLANSYIL VFARERIKSR VVINCAGLHS DVVAAMAGLD IDETGYRLHY CRGEYYRLRR RYEFAHLVYP LPEKNGLGIH LTLDLQGGQR LGPDTRYVDT IDYSIDDSYK EKFYFAARRY LPWLEMEDLQ PDYAGIRPKL QTEGGEFRDF VINEESCHGL PGFINLIGIE SPGLTAALAI ARYAAKLVEN MFN HMM: 2-42 KYETEVD IVVVGAGVIG LAAAVELAHR NPAAQILLIE KNRG ALI: 5-45 TEVD IVVVGAGVIG LAAAVELAHR NPAAQILLIE KNRGYGQ ENV: 4-49 ETEVD IVVVGAGVIG LAAAVELAHR NPAAQILLIE KNRGYGQEVS S Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MNINTETRV LGLLGNPVEH SLSPFLHNQV FALLGLNCVY LPFKVETGKL EDAVRGIRGL NLAGVNVTIP YKEAVIPYLD ELSPEASACG AVNVIKNSAG GLTGYNTDGI GFLGALRQEN ITEHKRVLFI GAGGAARSLA ATLANSGASH LYFLDPDQRR AAEAAEWLKK QYVCETVTDL MNEENFRAMA VNADLLINCS PVGMYPAVDE SPVVSLDSVP DTAVLCDIIY NPLRTKLLQM GQERGLKCIT GLSMFAHQAA LTLKILLDAD PPLEYMQSEL VKRLELES
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280
PF08501: 11-94 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MNINTETRV LGLLGNPVEH SLSPFLHNQV FALLGLNCVY LPFKVETGKL EDAVRGIRGL NLAGVNVTIP YKEAVIPYLD ELSPEASACG AVNVIKNSAG GLTGYNTDGI GFLGALRQEN ITEHKRVLFI GAGGAARSLA ATLANSGASH LYFLDPDQRR AAEAAEWLKK QYVCETVTDL MNEENFRAMA VNADLLINCS PVGMYPAVDE SPVVSLDSVP DTAVLCDIIY NPLRTKLLQM GQERGLKCIT GLSMFAHQAA LTLKILLDAD PPLEYMQSEL VKRLELES HMM: 175-233 VTDL MNEENFRAMA VNADLLINCS PVGMYPAVDE SPVVSLDSVP DTAVLCDIIY NPLRT ALI: 122-183 HKRVLFI GAGGAARSLA ATLANSGASH LYFLDPDQRR AAEAAEWLKK QYVCETVTDL MNEEN ENV: 115-197 RQEN ITEHKRVLFI GAGGAARSLA ATLANSGASH LYFLDPDQRR AAEAAEWLKK QYVCETVTDL MNEENFRAMA VNADLLINC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280
Sequence: MSMSAPRPG RKYTYGDYLK WPDEERWEII DGVPYEMSPA PSTEHQRVST QLLGQLIPFA ANKPCNIFHA PFDVRLPWGN EKDEEIDTVV QPDICVICDP AKIDARGCKG APDLVIEILS HATAKKDLSE KYNLYEKCGV REYWVVFPKE KVLDVYHLND NGIYDKTGTY FDSDIMECEL FPGLAIKLED VFAGI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
PF05685: 15-187 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
Sequence: MSMSAPRPG RKYTYGDYLK WPDEERWEII DGVPYEMSPA PSTEHQRVST QLLGQLIPFA ANKPCNIFHA PFDVRLPWGN EKDEEIDTVV QPDICVICDP AKIDARGCKG APDLVIEILS HATAKKDLSE KYNLYEKCGV REYWVVFPKE KVLDVYHLND NGIYDKTGTY FDSDIMECEL FPGLAIKLED VFAGI HMM: 34-73 EMSPA PSTEHQRVST QLLGQLIPFA ANKPCNIFHA PFDVR ALI: 65-104 IFHA PFDVRLPWGN EKDEEIDTVV QPDICVICDP AKIDAR ENV: 42-112 EHQRVST QLLGQLIPFA ANKPCNIFHA PFDVRLPWGN EKDEEIDTVV QPDICVICDP AKIDARGCKG APDL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MSMSAPKPG RKYTYGDYLK WPGEERWEII DGVPYMMSPA PSSEHQRILL EIASQLHLYL RGKSCMVFPA PFDVRLPRGD EKDEDIQTVV QPDIVVICDN SKLDRRGYRG APAMVVEILS PQTTKKDLRE KYDLYERSGI KEYWVVFPLD QVLDVYLLDE EGKYQKNRTY EKDARVKPSI FEDLEIDLGL VFRDN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
PF05685: 15-186 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
Sequence: MSMSAPKPG RKYTYGDYLK WPGEERWEII DGVPYMMSPA PSSEHQRILL EIASQLHLYL RGKSCMVFPA PFDVRLPRGD EKDEDIQTVV QPDIVVICDN SKLDRRGYRG APAMVVEILS PQTTKKDLRE KYDLYERSGI KEYWVVFPLD QVLDVYLLDE EGKYQKNRTY EKDARVKPSI FEDLEIDLGL VFRDN HMM: 26-72 EII DGVPYMMSPA PSSEHQRILL EIASQLHLYL RGKSCMVFPA PFDV ALI: 57-103 YL RGKSCMVFPA PFDVRLPRGD EKDEDIQTVV QPDIVVICDN SKLDR ENV: 47-109 LL EIASQLHLYL RGKSCMVFPA PFDVRLPRGD EKDEDIQTVV QPDIVVICDN SKLDRRGYRG A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MDFKLSEEQ ELVRQNMREF AMKYVDPIAA EIDENSRFPA EVVAKLGEMG YMGMPYPVEF GGSGTDYVTY ALAVEELSKS CAATGFTMSV HTSLALGPIN NFGNEEQKKK FLTPLCQGKH LGAFALTEPG AGTDVGAATT TAVLDGDEYV LNGTKTFTSN GPVADTFVTF AWTDKSAGSK GMSAFIVPKD APGLRVGEHF MKMGIRASQT SEIIFKDCRI PKANLLGEEG QGLKIAMNCF DHGRIGIAAQ AVGIAQAALE ESIRYAKERV QFGKPIAKNQ AVQWWIADMA TDITCARFLY MQAAWLKDQG LPFTKEASMA KVFAAEMCMK HTIKAVQIHG GYGYIKGQKV ERLMRDAKIT EIYEGTSEAQ RMVIANNLLR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-217 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 228-377 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MDFKLSEEQ ELVRQNMREF AMKYVDPIAA EIDENSRFPA EVVAKLGEMG YMGMPYPVEF GGSGTDYVTY ALAVEELSKS CAATGFTMSV HTSLALGPIN NFGNEEQKKK FLTPLCQGKH LGAFALTEPG AGTDVGAATT TAVLDGDEYV LNGTKTFTSN GPVADTFVTF AWTDKSAGSK GMSAFIVPKD APGLRVGEHF MKMGIRASQT SEIIFKDCRI PKANLLGEEG QGLKIAMNCF DHGRIGIAAQ AVGIAQAALE ESIRYAKERV QFGKPIAKNQ AVQWWIADMA TDITCARFLY MQAAWLKDQG LPFTKEASMA KVFAAEMCMK HTIKAVQIHG GYGYIKGQKV ERLMRDAKIT EIYEGTSEAQ RMVIANNLLR HMM: 37-293 PA EVVAKLGEMG YMGMPYPVEF GGSGTDYVTY ALAVEELSKS CAATGFTMSV HTSLALGPIN NFGNEEQKKK FLTPLCQGKH LGAFALTEPG AGTDVGAATT TAVLDGDEYV LNGTKTFTSN GPVADTFVTF AWTDKSAGSK GMSAFIVPKD APGLRVGEHF MKMGIRASQT SEIIFKDCRI PKANLLGEEG QGLKIAMNCF DHGRIGIAAQ AVGIAQAALE ESIRYAKERV QFGKPIAKNQ AVQWWIADMA TDITC ALI: 30-281 IDENSRFPA EVVAKLGEMG YMGMPYPVEF GGSGTDYVTY ALAVEELSKS CAATGFTMSV HTSLALGPIN NFGNEEQKKK FLTPLCQGKH LGAFALTEPG AGTDVGAATT TAVLDGDEYV LNGTKTFTSN GPVADTFVTF AWTDKSAGSK GMSAFIVPKD APGLRVGEHF MKMGIRASQT SEIIFKDCRI PKANLLGEEG QGLKIAMNCF DHGRIGIAAQ AVGIAQAALE ESIRYAKERV QFGKPIAKNQ AVQ ENV: 8-289 Q ELVRQNMREF AMKYVDPIAA EIDENSRFPA EVVAKLGEMG YMGMPYPVEF GGSGTDYVTY ALAVEELSKS CAATGFTMSV HTSLALGPIN NFGNEEQKKK FLTPLCQGKH LGAFALTEPG AGTDVGAATT TAVLDGDEYV LNGTKTFTSN GPVADTFVTF AWTDKSAGSK GMSAFIVPKD APGLRVGEHF MKMGIRASQT SEIIFKDCRI PKANLLGEEG QGLKIAMNCF DHGRIGIAAQ AVGIAQAALE ESIRYAKERV QFGKPIAKNQ AVQWWIADMA T Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MNFTFTKEQ LMIQQMAKEF AEKYLEPVAE QVDRENKIPD EILKGLAELD LFGIPYAEEY GGAGGGYDGY VLAMEQISRA CSGVAMTISA HSLSLSAINV FGTEEQKKKY MTPACKGEHI ASFAFTEPQT GSDPKQLATT AKKVGNEYIL NGTKRFISNA NWPGVAVIFA VDDQTGKPSG FLVEKFCEGY SISEPWDKIG MHGGQLLDIY LKDVRVPAEN MLGGPSMGYP ILQLGISFGK VGVSSTALGG ILAAYEEGVK YATEKMHRDA PISKFQAVQL RIADMAIKYE AARWLTYRLG CLANNVKDPR AFAKEAALTK TFVCDTMVDV ARISIDIHGS YGLMNDYKIA KIYKDAIIGP EIEGVADMQK LIVAGVTLAE RK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-117 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 120-213 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF00441: 226-373 ◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌
Sequence: MNFTFTKEQ LMIQQMAKEF AEKYLEPVAE QVDRENKIPD EILKGLAELD LFGIPYAEEY GGAGGGYDGY VLAMEQISRA CSGVAMTISA HSLSLSAINV FGTEEQKKKY MTPACKGEHI ASFAFTEPQT GSDPKQLATT AKKVGNEYIL NGTKRFISNA NWPGVAVIFA VDDQTGKPSG FLVEKFCEGY SISEPWDKIG MHGGQLLDIY LKDVRVPAEN MLGGPSMGYP ILQLGISFGK VGVSSTALGG ILAAYEEGVK YATEKMHRDA PISKFQAVQL RIADMAIKYE AARWLTYRLG CLANNVKDPR AFAKEAALTK TFVCDTMVDV ARISIDIHGS YGLMNDYKIA KIYKDAIIGP EIEGVADMQK LIVAGVTLAE RK HMM: 23-235 LEPVAE QVDRENKIPD EILKGLAELD LFGIPYAEEY GGAGGGYDGY VLAMEQISRA CSGVAMTISA HSLSLSAINV FGTEEQKKKY MTPACKGEHI ASFAFTEPQT GSDPKQLATT AKKVGNEYIL NGTKRFISNA NWPGVAVIFA VDDQTGKPSG FLVEKFCEGY SISEPWDKIG MHGGQLLDIY LKDVRVPAEN MLGGPSMGYP ILQLGIS ALI: 15-225 AKEF AEKYLEPVAE QVDRENKIPD EILKGLAELD LFGIPYAEEY GGAGGGYDGY VLAMEQISRA CSGVAMTISA HSLSLSAINV FGTEEQKKKY MTPACKGEHI ASFAFTEPQT GSDPKQLATT AKKVGNEYIL NGTKRFISNA NWPGVAVIFA VDDQTGKPSG FLVEKFCEGY SISEPWDKIG MHGGQLLDIY LKDVRVPAEN MLGGPSM ENV: 7-238 EQ LMIQQMAKEF AEKYLEPVAE QVDRENKIPD EILKGLAELD LFGIPYAEEY GGAGGGYDGY VLAMEQISRA CSGVAMTISA HSLSLSAINV FGTEEQKKKY MTPACKGEHI ASFAFTEPQT GSDPKQLATT AKKVGNEYIL NGTKRFISNA NWPGVAVIFA VDDQTGKPSG FLVEKFCEGY SISEPWDKIG MHGGQLLDIY LKDVRVPAEN MLGGPSMGYP ILQLGISFGK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MAYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
PF01977: 9-423 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MAYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE HMM: 2-413 YKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDP ALI: 3-426 KDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDV ENV: 2-459 YKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP K Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MAYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE HMM: 1-478 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY ALI: 1-479 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY G ENV: 1-481 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MAYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE HMM: 1-403 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEV ALI: 1-418 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM ENV: 1-481 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
PF00384: 2-332 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF01568: 414-520 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 253-313 DPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAI ALI: 35-95 NVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTE ENV: 26-97 PVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 385-470 HKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RR ALI: 96-183 AYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNV ENV: 91-193 ETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 610-684 ALI: 262-334 ALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLG ENV: 257-356 DH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 838-912 ALI: 412-487 YPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENV ENV: 402-498 QEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 251-311 VSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRK ALI: 36-96 VRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEA ENV: 17-102 IG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 392-462 GLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGE ALI: 105-175 EKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVN ENV: 97-184 YE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 610-679 ALI: 265-332 NLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTR ENV: 231-337 INKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 820-894 ALI: 411-486 EYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKEN ENV: 401-508 FQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 246-330 GEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LS ALI: 11-96 ATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEA ENV: 7-99 LE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 408-481 P DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTD ALI: 103-177 VVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPL ENV: 96-185 AYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 592-700 ALI: 231-335 INKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGY ENV: 187-341 CD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 841-921 ALI: 412-493 YPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFH ENV: 402-506 QEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNAS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
PF00384: 1-301 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
PF01568: 400-504 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 254-314 LVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMF ALI: 21-81 AARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TEN ENV: 7-82 PT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 386-470 HIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GV ALI: 82-168 YEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV ENV: 79-180 TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 612-675 ALI: 249-309 EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ T ENV: 240-319 DANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG Y Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 874-915 ALI: 432-473 NPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWM ENV: 426-483 KEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 251-311 LEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TIC ALI: 21-81 AARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TEN ENV: 3-93 IGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 389-462 PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKV ALI: 87-160 AI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VC ENV: 82-164 YEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 591-641 ALI: 232-281 ENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECD ENV: 193-311 REKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TIC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 860-908 ALI: 435-478 DADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ENV: 429-500 SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 256-330 VQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IW ALI: 7-81 PT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TEN ENV: 1-82 FLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 403-480 TGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN AT ALI: 84-161 ELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCP ENV: 81-170 NYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 601-696 ALI: 225-315 KAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFV ENV: 173-324 DMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 877-915 ALI: 432-470 NPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GV ENV: 428-480 M SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN AT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
PF00384: 9-327 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF01568: 413-518 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 254-314 NSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEP ALI: 35-95 AARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTEN ENV: 12-96 ELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 386-471 GKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVV ALI: 96-183 YEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQ ENV: 93-197 TENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 615-681 ALI: 266-330 EFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SR ENV: 258-343 I RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 874-915 ALI: 446-487 NPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWM ENV: 436-497 SVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 251-311 TDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKA ALI: 35-95 AARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTEN ENV: 11-105 AELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVEN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 389-464 TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVT ALI: 101-176 ATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPI ENV: 95-251 NYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 585-641 ALI: 240-295 AMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECD ENV: 219-331 PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 857-908 ALI: 446-492 NPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYS ENV: 411-516 YPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 245-330 GENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SR ALI: 10-95 DAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTEN ENV: 4-96 ISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 402-480 PPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RV ALI: 97-175 EA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCP ENV: 94-198 ENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 629-700 ALI: 265-333 LEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGY ENV: 229-337 MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 874-917 ALI: 443-486 AELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIW ENV: 407-498 PD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
PF00384: 429-475 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF01568: 718-835 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 247-465 LF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADL ALI: 27-230 SM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VN ENV: 3-250 HIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 634-687 DVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTE ALI: 428-479 F LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL Y ENV: 414-500 VPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 243-464 DMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKAD ALI: 27-232 SM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNAL ENV: 5-247 VDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 632-681 GDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEP ALI: 429-476 LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVK ENV: 389-502 VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 831-898 YKAWLCDI RRA ALI: 725-795 HWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVH ENV: 705-816 DKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 248-481 F HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAG ALI: 12-232 CALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNAL ENV: 5-248 VDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 650-701 TGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKV ALI: 429-478 LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL ENV: 422-486 IQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 875-908 ALI: 748-781 E LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVT ENV: 745-787 MMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
PF00384: 8-436 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
PF01568: 683-801 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 215-313 CYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPA ALI: 4-102 FGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTN ENV: 2-113 PSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 385-480 PTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND AT ALI: 155-250 VFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM AN ENV: 139-283 AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 634-687 GMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYG ALI: 390-441 FLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLY ENV: 383-460 KIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 213-311 IRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNN ALI: 5-103 GRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNA ENV: 2-114 PSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 383-465 KIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEAS ALI: 155-237 VFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALR ENV: 144-247 VKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 838-894 ALI: 698-753 T RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTL ENV: 660-800 VQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 231-330 GGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QF ALI: 4-103 FGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNA ENV: 1-112 SPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 400-481 AGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATG ALI: 155-236 VFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQAL ENV: 135-251 YQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 649-700 ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RN ALI: 390-439 FLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR T ENV: 377-446 EG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSND Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
PF04879: 43-95 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00384: 98-135 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI HMM: 4-27 RRGFL KLSGLSVAVV ASGLGFDLE ALI: 1-23 KFTRRGFL KLSGLSVAVV ASGLG ENV: 1-40 KFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI HMM: 104-202 YRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI ALI: 77-173 IN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEE ENV: 49-180 HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI HMM: 97-160 ER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EG ALI: 73-134 PDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDK ENV: 56-150 GLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI HMM: 20-33 SGLGFDLEA TAAHG ALI: 3-16 TRRGFL KLSGLSVA ENV: 2-30 FTRRGFL KLSGLSVAVV ASGLGFDLEA TA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI HMM: 124-181 IAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLA ALI: 81-136 TLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTW ENV: 63-161 DGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
PF04879: 45-99 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI HMM: 4-36 RRQFL KVTGATAASF ALVDLGFDLQ ATASAAKE ALI: 1-34 KVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAA ENV: 1-44 KVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI HMM: 118-165 Q KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSE ALI: 109-154 EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNF ENV: 59-206 VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI HMM: 115-154 KRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNF ALI: 109-146 EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKI ENV: 85-160 NQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI HMM: 19-46 ALVDLGFDLQ ATASAAKELR IKNVTPTP ALI: 2-29 VTRRQFL KVTGATAASF ALVDLGFDLQ A ENV: 1-48 KVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI HMM: 127-178 SD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG ALI: 91-151 SKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRD ENV: 60-162 IYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLED Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MVDLVKLII NGKEVEAPAG STILQAAELA GIEIPRLCYD KDLSPLGACR LCVVEVKGNR LLPASCVTPV FQGMEVETES PAVVEARKTI LELLIANHPL DCLTCEKAGA CKLQDYCYRY GIKGSPFVGQ KHAYAIDDSN PFIVRDLNKC ILCGACVRAC EELTGADNLS YLKRGFHRKA TTAGDVDYID SDCVFCGQCV AVCPTGALTE KTMVGQGRRW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA ALSSARCTNE ENFLVSKFSR AVMGTNNVDH CART
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 4-79 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
PF10588: 85-124 ◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌
PF12838: 147-206 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF04879: 221-275 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00384: 277-352 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MVDLVKLII NGKEVEAPAG STILQAAELA GIEIPRLCYD KDLSPLGACR LCVVEVKGNR LLPASCVTPV FQGMEVETES PAVVEARKTI LELLIANHPL DCLTCEKAGA CKLQDYCYRY GIKGSPFVGQ KHAYAIDDSN PFIVRDLNKC ILCGACVRAC EELTGADNLS YLKRGFHRKA TTAGDVDYID SDCVFCGQCV AVCPTGALTE KTMVGQGRRW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA ALSSARCTNE ENFLVSKFSR AVMGTNNVDH CART HMM: 57-171 NR LLPASCVTPV FQGMEVETES PAVVEARKTI LELLIANHPL DCLTCEKAGA CKLQDYCYRY GIKGSPFVGQ KHAYAIDDSN PFIVRDLNKC ILCGACVRAC EELTGADNLS YLK ALI: 217-319 RW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA A ENV: 206-349 LTE KTMVGQGRRW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA ALSSARCTNE ENFLVSKFSR AVMGTNNVDH C Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MVDLVKLII NGKEVEAPAG STILQAAELA GIEIPRLCYD KDLSPLGACR LCVVEVKGNR LLPASCVTPV FQGMEVETES PAVVEARKTI LELLIANHPL DCLTCEKAGA CKLQDYCYRY GIKGSPFVGQ KHAYAIDDSN PFIVRDLNKC ILCGACVRAC EELTGADNLS YLKRGFHRKA TTAGDVDYID SDCVFCGQCV AVCPTGALTE KTMVGQGRRW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA ALSSARCTNE ENFLVSKFSR AVMGTNNVDH CART HMM: 115-187 CYRY GIKGSPFVGQ KHAYAIDDSN PFIVRDLNKC ILCGACVRAC EELTGADNLS YLKRGFHRKA TTAGDVDYI ALI: 251-319 NPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA A ENV: 217-330 RW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA ALSSARCTNE EN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MELIKITID GKEVEVPAGT TIMKAADSVG INIPRLCYDP DLSALGACRL CVVEVEGNRL LPASCVTPIF PGMVVNTNSP AVVEARKTIL ELLVANHPLD CMTCDKLGDC KLADYCYQYG VKESPFVGEK HEYAIDDTNP FILRDLNKCI LCGACVRACE EMTGQDNLSY LNRGFHRKAT TAGDVDYIDS DCVFCGQCVA VCPTGALQEK TMVGQGRRWD IDRVRTTCPF CGTGCNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA LSSARCTNEE NYLVQKFTRA VMGNNNVDHC ART
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 2-78 ◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
PF10588: 84-123 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌
PF12838: 146-205 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF04879: 221-274 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF00384: 276-351 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MELIKITID GKEVEVPAGT TIMKAADSVG INIPRLCYDP DLSALGACRL CVVEVEGNRL LPASCVTPIF PGMVVNTNSP AVVEARKTIL ELLVANHPLD CMTCDKLGDC KLADYCYQYG VKESPFVGEK HEYAIDDTNP FILRDLNKCI LCGACVRACE EMTGQDNLSY LNRGFHRKAT TAGDVDYIDS DCVFCGQCVA VCPTGALQEK TMVGQGRRWD IDRVRTTCPF CGTGCNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA LSSARCTNEE NYLVQKFTRA VMGNNNVDHC ART HMM: 103-170 DKLGDC KLADYCYQYG VKESPFVGEK HEYAIDDTNP FILRDLNKCI LCGACVRACE EMTGQDNLSY LN ALI: 253-317 STVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFA ENV: 208-347 K TMVGQGRRWD IDRVRTTCPF CGTGCNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA LSSARCTNEE NYLVQKFTRA VMGNNNVDH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MELIKITID GKEVEVPAGT TIMKAADSVG INIPRLCYDP DLSALGACRL CVVEVEGNRL LPASCVTPIF PGMVVNTNSP AVVEARKTIL ELLVANHPLD CMTCDKLGDC KLADYCYQYG VKESPFVGEK HEYAIDDTNP FILRDLNKCI LCGACVRACE EMTGQDNLSY LNRGFHRKAT TAGDVDYIDS DCVFCGQCVA VCPTGALQEK TMVGQGRRWD IDRVRTTCPF CGTGCNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA LSSARCTNEE NYLVQKFTRA VMGNNNVDHC ART HMM: 91-187 LVANHPLD CMTCDKLGDC KLADYCYQYG VKESPFVGEK HEYAIDDTNP FILRDLNKCI LCGACVRACE EMTGQDNLSY LNRGFHRKAT TAGDVDYID ALI: 233-318 CNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA ENV: 214-347 GRRWD IDRVRTTCPF CGTGCNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA LSSARCTNEE NYLVQKFTRA VMGNNNVDH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MIKLTIDGK EIEVARGTML LDACRQAGAD IPTLCYDPDL RLAGSCRMCV VDVKGRPALV ASCVAPAENG MVVQTESDDV VESRKIILEL LAARHKFECP TCEKDGDCKL QDYMYRYGVK ESRYDGEGPH FGMEDPNPFI ERDYDKCIMC TRCVRACDGI TGAQAINVKD RGHHAKIAAP FDGKLADSTC VFCGQCIMVC PVGALTSKVA AGKGKPAQNE KVLTTCTYCG TGCTLELNVN NDRVVGVTSN RDADWSPVNK GALCVKGRFG WDFIHSPDRL TTPMIRENGE LRPASWDEAL DFAAGKIKGI KEKYGSDSLA MFSSARVTNE ENYIAQKLMR AVIGTNNVDH CARL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 0-76 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
PF10588: 82-122 ◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
PF14697: 141-203 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF04879: 219-274 ♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF00384: 277-353 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MIKLTIDGK EIEVARGTML LDACRQAGAD IPTLCYDPDL RLAGSCRMCV VDVKGRPALV ASCVAPAENG MVVQTESDDV VESRKIILEL LAARHKFECP TCEKDGDCKL QDYMYRYGVK ESRYDGEGPH FGMEDPNPFI ERDYDKCIMC TRCVRACDGI TGAQAINVKD RGHHAKIAAP FDGKLADSTC VFCGQCIMVC PVGALTSKVA AGKGKPAQNE KVLTTCTYCG TGCTLELNVN NDRVVGVTSN RDADWSPVNK GALCVKGRFG WDFIHSPDRL TTPMIRENGE LRPASWDEAL DFAAGKIKGI KEKYGSDSLA MFSSARVTNE ENYIAQKLMR AVIGTNNVDH CARL HMM: 110-177 DYMYRYGVK ESRYDGEGPH FGMEDPNPFI ERDYDKCIMC TRCVRACDGI TGAQAINVKD RGHHAKIAA ALI: 262-325 CVKGRFG WDFIHSPDRL TTPMIRENGE LRPASWDEAL DFAAGKIKGI KEKYGSDSLA MFSSARV ENV: 244-352 GVTSN RDADWSPVNK GALCVKGRFG WDFIHSPDRL TTPMIRENGE LRPASWDEAL DFAAGKIKGI KEKYGSDSLA MFSSARVTNE ENYIAQKLMR AVIGTNNVDH CARL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MEWVNVIIA ALFFLAILYI ILQVLFKPVK LLWKLAINSL MGLVLLLISN YIGAYFQFDL PVNIITVLIA GFLGLPGIIL LICFQLLVR
10 20 30 40 50 60 70 80
PF07441: 13-85 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
Sequence: MEWVNVIIA ALFFLAILYI ILQVLFKPVK LLWKLAINSL MGLVLLLISN YIGAYFQFDL PVNIITVLIA GFLGLPGIIL LICFQLLVR HMM: 225-276 ALI: 2-54 WVNVIIA ALFFLAILYI ILQVLFKPVK LLWKLAINSL MGLVLLLISN YIGAYF ENV: 1-54 EWVNVIIA ALFFLAILYI ILQVLFKPVK LLWKLAINSL MGLVLLLISN YIGAYF Position: 10 20 30 40 50 60 70 80
Sequence: MKTFPELFS PAYIGKLLVK NRIVMAPMLV SYASSDGEVS ERLLDYYEAR ARGGAGLIVV EAACVDAPTG RESFRQINID SLRYVAGLQQ LAQHIKAYGC RTFIQLFHAG RQTSSLFTGV QPVAPSPLAC PMVKEIPREL TGEEIKEIEN KFSQAAAYAF MAGFDGVELH AAHGYLINQF LSPHSNLRQD EYGGSLENRM RFLLNIIKKI KTSSPGLIIS VRINMDDFVP GGLELKESVE ICQHLEQAGV ELINCSSGTY ESGLKSIEPA SYKEGWRVYL AGELKKWIHI PVIAGGMLNN PAFANQLIAG GQADFIFLGR SLLADSEWPH KVRESGTEDI RPCIRCNNCI DNNFRGMMVD CSVNPLTGRE RHFSQEGKKL LHKANVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACLPPH KHRVAYLRDY LIRQVEKSGV EAFLNCSFNL ESLPDLNPDY LLIATGSKPL LPQIPGWDQS YCLGIREVLE RKPEIKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQNK YLAADMEKKN RRDLMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFTPNNALYI EAQNRHKNVY LIGDAFQVKG FKNAFLQGEA VAHMIATGLK K
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
PF00724: 5-333 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF07992: 383-609 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
Sequence: MKTFPELFS PAYIGKLLVK NRIVMAPMLV SYASSDGEVS ERLLDYYEAR ARGGAGLIVV EAACVDAPTG RESFRQINID SLRYVAGLQQ LAQHIKAYGC RTFIQLFHAG RQTSSLFTGV QPVAPSPLAC PMVKEIPREL TGEEIKEIEN KFSQAAAYAF MAGFDGVELH AAHGYLINQF LSPHSNLRQD EYGGSLENRM RFLLNIIKKI KTSSPGLIIS VRINMDDFVP GGLELKESVE ICQHLEQAGV ELINCSSGTY ESGLKSIEPA SYKEGWRVYL AGELKKWIHI PVIAGGMLNN PAFANQLIAG GQADFIFLGR SLLADSEWPH KVRESGTEDI RPCIRCNNCI DNNFRGMMVD CSVNPLTGRE RHFSQEGKKL LHKANVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACLPPH KHRVAYLRDY LIRQVEKSGV EAFLNCSFNL ESLPDLNPDY LLIATGSKPL LPQIPGWDQS YCLGIREVLE RKPEIKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQNK YLAADMEKKN RRDLMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFTPNNALYI EAQNRHKNVY LIGDAFQVKG FKNAFLQGEA VAHMIATGLK K HMM: 5-49 ELFS PAYIGKLLVK NRIVMAPMLV SYASSDGEVS ERLLDYYEAR A ALI: 383-425 NVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACL ENV: 380-431 HKANVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACLPPH KHR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MKTFPELFS PAYIGKLLVK NRIVMAPMLV SYASSDGEVS ERLLDYYEAR ARGGAGLIVV EAACVDAPTG RESFRQINID SLRYVAGLQQ LAQHIKAYGC RTFIQLFHAG RQTSSLFTGV QPVAPSPLAC PMVKEIPREL TGEEIKEIEN KFSQAAAYAF MAGFDGVELH AAHGYLINQF LSPHSNLRQD EYGGSLENRM RFLLNIIKKI KTSSPGLIIS VRINMDDFVP GGLELKESVE ICQHLEQAGV ELINCSSGTY ESGLKSIEPA SYKEGWRVYL AGELKKWIHI PVIAGGMLNN PAFANQLIAG GQADFIFLGR SLLADSEWPH KVRESGTEDI RPCIRCNNCI DNNFRGMMVD CSVNPLTGRE RHFSQEGKKL LHKANVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACLPPH KHRVAYLRDY LIRQVEKSGV EAFLNCSFNL ESLPDLNPDY LLIATGSKPL LPQIPGWDQS YCLGIREVLE RKPEIKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQNK YLAADMEKKN RRDLMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFTPNNALYI EAQNRHKNVY LIGDAFQVKG FKNAFLQGEA VAHMIATGLK K HMM: 173-207 YLINQF LSPHSNLRQD EYGGSLENRM RFLLNIIKK ALI: 503-536 IKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQ ENV: 497-546 LE RKPEIKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQNK YLAADMEK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MKTFPELFS PAYIGKLLVK NRIVMAPMLV SYASSDGEVS ERLLDYYEAR ARGGAGLIVV EAACVDAPTG RESFRQINID SLRYVAGLQQ LAQHIKAYGC RTFIQLFHAG RQTSSLFTGV QPVAPSPLAC PMVKEIPREL TGEEIKEIEN KFSQAAAYAF MAGFDGVELH AAHGYLINQF LSPHSNLRQD EYGGSLENRM RFLLNIIKKI KTSSPGLIIS VRINMDDFVP GGLELKESVE ICQHLEQAGV ELINCSSGTY ESGLKSIEPA SYKEGWRVYL AGELKKWIHI PVIAGGMLNN PAFANQLIAG GQADFIFLGR SLLADSEWPH KVRESGTEDI RPCIRCNNCI DNNFRGMMVD CSVNPLTGRE RHFSQEGKKL LHKANVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACLPPH KHRVAYLRDY LIRQVEKSGV EAFLNCSFNL ESLPDLNPDY LLIATGSKPL LPQIPGWDQS YCLGIREVLE RKPEIKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQNK YLAADMEKKN RRDLMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFTPNNALYI EAQNRHKNVY LIGDAFQVKG FKNAFLQGEA VAHMIATGLK K HMM: 300-344 AFANQLIAG GQADFIFLGR SLLADSEWPH KVRESGTEDI RPCIRC ALI: 552-601 LMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFT ENV: 548-614 N RRDLMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFTPNNALYI EAQNRH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MNKVDVAII GAGVVGLAIA WKIASKTGKT VVVIERNNKY GQEISSRNSE VIHSGLYYSP SMLKTQLCVR GNSLLYEFCE QRNVAHYRRG KILVALNQGE EEQLDALYNN ALSNTVSVNR LTGRKVLEME PEVLAYSGLY FPNTGTVDVH ELMQALFFEG RQAGVVYLFY SIVKEAVYTG SGYEIGTQRE TIHAQNVINC AGLGAETIAQ LIGIDTIKSG YHLHPCKGDY FKIKRKLKIQ HLVYSVPTSN SLGIHLSMDR EGYLRLGPNA YYVEDLNYSV NESHGTEFFQ AARQYIPSLK MEDLMPDFAG IRPKIQGPGE EMKDFVIKDE SDPGYPGWIN LIGIESPGLT SCLAIGDYVK ELI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
PF01266: 4-361 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MNKVDVAII GAGVVGLAIA WKIASKTGKT VVVIERNNKY GQEISSRNSE VIHSGLYYSP SMLKTQLCVR GNSLLYEFCE QRNVAHYRRG KILVALNQGE EEQLDALYNN ALSNTVSVNR LTGRKVLEME PEVLAYSGLY FPNTGTVDVH ELMQALFFEG RQAGVVYLFY SIVKEAVYTG SGYEIGTQRE TIHAQNVINC AGLGAETIAQ LIGIDTIKSG YHLHPCKGDY FKIKRKLKIQ HLVYSVPTSN SLGIHLSMDR EGYLRLGPNA YYVEDLNYSV NESHGTEFFQ AARQYIPSLK MEDLMPDFAG IRPKIQGPGE EMKDFVIKDE SDPGYPGWIN LIGIESPGLT SCLAIGDYVK ELI HMM: 4-42 DVAII GAGVVGLAIA WKIASKTGKT VVVIERNNKY GQEI ALI: 3-40 VDVAII GAGVVGLAIA WKIASKTGKT VVVIERNNKY GQ ENV: 1-51 NKVDVAII GAGVVGLAIA WKIASKTGKT VVVIERNNKY GQEISSRNSE VIH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
PF02901: 3-588 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF01228: 604-710 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 272-428 TENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS ALI: 204-361 SLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEF ENV: 192-369 IQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS T Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 490-561 TFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQ ALI: 408-480 A RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AY ENV: 391-497 ACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 644-830 VPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM ALI: 538-725 P KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFY ENV: 529-727 SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 297-431 EY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQ ALI: 221-353 RPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRN ENV: 177-362 EN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 510-580 LSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TI ALI: 409-479 RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY A ENV: 389-507 GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 662-846 LLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM ALI: 538-724 P KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTF ENV: 525-727 RGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 490-552 TFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAV ALI: 418-480 Y AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AY ENV: 400-517 GKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 633-817 ARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM ALI: 538-724 P KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTF ENV: 530-727 DFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MQDLYWECK VCEACGVCGK SEEECRLYDE YYGFGKSPGA GKAERGSLAV LERDARKLNQ ANQGIINRLN GRIVKVIEGE STALLTIAMG EHYISSMMPL SRFRESGKKI GDLLAVAFKS IDVKVMN
10 20 30 40 50 60 70 80 90 100 110 120
Sequence: MQDLYWECK VCEACGVCGK SEEECRLYDE YYGFGKSPGA GKAERGSLAV LERDARKLNQ ANQGIINRLN GRIVKVIEGE STALLTIAMG EHYISSMMPL SRFRESGKKI GDLLAVAFKS IDVKVMN HMM: 705-752 ALI: 25-73 LYDE YYGFGKSPGA GKAERGSLAV LERDARKLNQ ANQGIINRLN GRIVK ENV: 11-96 EACGVCGK SEEECRLYDE YYGFGKSPGA GKAERGSLAV LERDARKLNQ ANQGIINRLN GRIVKVIEGE STALLTIAMG EHYISSMM Position: 10 20 30 40 50 60 70 80 90 100 110 120
Sequence: MNFMLSEEQ ELIRSNAREF ALKYIEPVAT KIDQESRHPV EVFDKLAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQWFIANMA TDIDAARFLY MNAAFIKDQG KPFSVAASKA KLFCSECAAR HTTKAVQIQG GYGFMKGAKV ERFYRDVKLT EIGEGTSEAQ RMIIAGSVLR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-217 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 228-377 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MNFMLSEEQ ELIRSNAREF ALKYIEPVAT KIDQESRHPV EVFDKLAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQWFIANMA TDIDAARFLY MNAAFIKDQG KPFSVAASKA KLFCSECAAR HTTKAVQIQG GYGFMKGAKV ERFYRDVKLT EIGEGTSEAQ RMIIAGSVLR HMM: 44-293 LAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQWFIANMA TDIDA ALI: 37-281 PV EVFDKLAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQ ENV: 9-288 ELIRSNAREF ALKYIEPVAT KIDQESRHPV EVFDKLAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQWFIANMA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MNFMLSEEQ ELIRSNAREF ALKYIEPVAT KIDQESRHPV EVFDKLAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQWFIANMA TDIDAARFLY MNAAFIKDQG KPFSVAASKA KLFCSECAAR HTTKAVQIQG GYGFMKGAKV ERFYRDVKLT EIGEGTSEAQ RMIIAGSVLR HMM: 343-387 MKGAKV ERFYRDVKLT EIGEGTSEAQ RMIIAGSVLR ALI: 314-358 AASKA KLFCSECAAR HTTKAVQIQG GYGFMKGAKV ERFYRDVKLT ENV: 302-364 AFIKDQG KPFSVAASKA KLFCSECAAR HTTKAVQIQG GYGFMKGAKV ERFYRDVKLT EIGEGT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MDFALSDES LMMRDMFRKF SKNEVEPLAA EIDRTHEFPM TTFKKMADLG LTGLPIPEEW GGAGASYLDF AMFVEELAKC CASTAVIMSV HTGLGCMSTY LYGSQRVKEK YLRALATGEI VGAYALTEPN AGSDAASLKC KAEDKGDYFL VNGSKIFITN GGVATTYCTF VKSDPSQGSG RGITCLVIEK DTPGFTMSKP VAKMGMNGSP TVELYFEDVK VPKENVLGEI NDGFKVAMGL LAGGRVTIAA QGLGIGEGAL DYTVQYIKER QQFGKPLAAN QGVQFMVADM AAALDAAQLL VYRAAWLKDN GLPHNKEASM AKKFATDTGM EVCTNCVQLM GGYGYCNEFP VERMMRDVKI TQIYEGSNQI QRMIIGRETI GRF
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-218 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 229-377 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MDFALSDES LMMRDMFRKF SKNEVEPLAA EIDRTHEFPM TTFKKMADLG LTGLPIPEEW GGAGASYLDF AMFVEELAKC CASTAVIMSV HTGLGCMSTY LYGSQRVKEK YLRALATGEI VGAYALTEPN AGSDAASLKC KAEDKGDYFL VNGSKIFITN GGVATTYCTF VKSDPSQGSG RGITCLVIEK DTPGFTMSKP VAKMGMNGSP TVELYFEDVK VPKENVLGEI NDGFKVAMGL LAGGRVTIAA QGLGIGEGAL DYTVQYIKER QQFGKPLAAN QGVQFMVADM AAALDAAQLL VYRAAWLKDN GLPHNKEASM AKKFATDTGM EVCTNCVQLM GGYGYCNEFP VERMMRDVKI TQIYEGSNQI QRMIIGRETI GRF HMM: 35-391 EFPM TTFKKMADLG LTGLPIPEEW GGAGASYLDF AMFVEELAKC CASTAVIMSV HTGLGCMSTY LYGSQRVKEK YLRALATGEI VGAYALTEPN AGSDAASLKC KAEDKGDYFL VNGSKIFITN GGVATTYCTF VKSDPSQGSG RGITCLVIEK DTPGFTMSKP VAKMGMNGSP TVELYFEDVK VPKENVLGEI NDGFKVAMGL LAGGRVTIAA QGLGIGEGAL DYTVQYIKER QQFGKPLAAN QGVQFMVADM AAALDAAQLL VYRAAWLKDN GLPHNKEASM AKKFATDTGM EVCTNCVQLM GGYGYCNEFP VERMMRDVKI TQIYEGSNQI QRMIIGRETI GRF ALI: 28-363 A EIDRTHEFPM TTFKKMADLG LTGLPIPEEW GGAGASYLDF AMFVEELAKC CASTAVIMSV HTGLGCMSTY LYGSQRVKEK YLRALATGEI VGAYALTEPN AGSDAASLKC KAEDKGDYFL VNGSKIFITN GGVATTYCTF VKSDPSQGSG RGITCLVIEK DTPGFTMSKP VAKMGMNGSP TVELYFEDVK VPKENVLGEI NDGFKVAMGL LAGGRVTIAA QGLGIGEGAL DYTVQYIKER QQFGKPLAAN QGVQFMVADM AAALDAAQLL VYRAAWLKDN GLPHNKEASM AKKFATDTGM EVCTNCVQLM GGYGYCNEFP VERMMRDVKI TQIYE ENV: 2-378 FALSDES LMMRDMFRKF SKNEVEPLAA EIDRTHEFPM TTFKKMADLG LTGLPIPEEW GGAGASYLDF AMFVEELAKC CASTAVIMSV HTGLGCMSTY LYGSQRVKEK YLRALATGEI VGAYALTEPN AGSDAASLKC KAEDKGDYFL VNGSKIFITN GGVATTYCTF VKSDPSQGSG RGITCLVIEK DTPGFTMSKP VAKMGMNGSP TVELYFEDVK VPKENVLGEI NDGFKVAMGL LAGGRVTIAA QGLGIGEGAL DYTVQYIKER QQFGKPLAAN QGVQFMVADM AAALDAAQLL VYRAAWLKDN GLPHNKEASM AKKFATDTGM EVCTNCVQLM GGYGYCNEFP VERMMRDVKI TQIYEGSNQI QRMIIGRETI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDFKLSEEQ ELIRENIREL VKKYLDPIAV EIDESSRYPA EVIEQLAAGG WMGMPYPVEY GGAGLDYVSY AMVIEEISRS CAATGFTVSC HTSLASGPIF NFGNEEQKQK YLVPLAKGQH IGAFAVTEPG AGTDVGAATT TATLDGDSYV LNGIKTFTSN GPVADTFVVF AFTDKSLGGK GMSAFIISKD NPGLKVGQHF YKMGIRASQT SEIILKDCRV PREDLLGKEG QGLQIAMSSF DHGRIGIAAQ AVGITQAALD ESISYSKQRV QFGKPISKNQ AIQWMIADMA TDIAAARFLY SYAAFLKDQK QPFSKEAAMA KVFAAEMSTR HTSKAVQIHG GYGYIKGQKV ERLMRDAKIT EIYEGTSEAQ RMVIAGNLLR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-217 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 228-377 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MDFKLSEEQ ELIRENIREL VKKYLDPIAV EIDESSRYPA EVIEQLAAGG WMGMPYPVEY GGAGLDYVSY AMVIEEISRS CAATGFTVSC HTSLASGPIF NFGNEEQKQK YLVPLAKGQH IGAFAVTEPG AGTDVGAATT TATLDGDSYV LNGIKTFTSN GPVADTFVVF AFTDKSLGGK GMSAFIISKD NPGLKVGQHF YKMGIRASQT SEIILKDCRV PREDLLGKEG QGLQIAMSSF DHGRIGIAAQ AVGITQAALD ESISYSKQRV QFGKPISKNQ AIQWMIADMA TDIAAARFLY SYAAFLKDQK QPFSKEAAMA KVFAAEMSTR HTSKAVQIHG GYGYIKGQKV ERLMRDAKIT EIYEGTSEAQ RMVIAGNLLR HMM: 24-293 DPIAV EIDESSRYPA EVIEQLAAGG WMGMPYPVEY GGAGLDYVSY AMVIEEISRS CAATGFTVSC HTSLASGPIF NFGNEEQKQK YLVPLAKGQH IGAFAVTEPG AGTDVGAATT TATLDGDSYV LNGIKTFTSN GPVADTFVVF AFTDKSLGGK GMSAFIISKD NPGLKVGQHF YKMGIRASQT SEIILKDCRV PREDLLGKEG QGLQIAMSSF DHGRIGIAAQ AVGITQAALD ESISYSKQRV QFGKPISKNQ AIQWMIADMA TDIAA ALI: 16-281 REL VKKYLDPIAV EIDESSRYPA EVIEQLAAGG WMGMPYPVEY GGAGLDYVSY AMVIEEISRS CAATGFTVSC HTSLASGPIF NFGNEEQKQK YLVPLAKGQH IGAFAVTEPG AGTDVGAATT TATLDGDSYV LNGIKTFTSN GPVADTFVVF AFTDKSLGGK GMSAFIISKD NPGLKVGQHF YKMGIRASQT SEIILKDCRV PREDLLGKEG QGLQIAMSSF DHGRIGIAAQ AVGITQAALD ESISYSKQRV QFGKPISKNQ AIQ ENV: 6-317 EEQ ELIRENIREL VKKYLDPIAV EIDESSRYPA EVIEQLAAGG WMGMPYPVEY GGAGLDYVSY AMVIEEISRS CAATGFTVSC HTSLASGPIF NFGNEEQKQK YLVPLAKGQH IGAFAVTEPG AGTDVGAATT TATLDGDSYV LNGIKTFTSN GPVADTFVVF AFTDKSLGGK GMSAFIISKD NPGLKVGQHF YKMGIRASQT SEIILKDCRV PREDLLGKEG QGLQIAMSSF DHGRIGIAAQ AVGITQAALD ESISYSKQRV QFGKPISKNQ AIQWMIADMA TDIAAARFLY SYAAFLKDQK QPFSKEAAM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MDFNLSKEQ SLIQQMAREF AEKSIAPVAK QIDEESKIPE EVLAGMAELD LFGIPFPEEY GGADGGYDGY VLAMEQIAKV SGGIAMTMAA HTLGLGAISA FGTEEQKKKY MIPGCKAKHI VSFAFTEPGT GSDPKQITTT AVKQGDFYIL NGTKRFISNA NYPGAMVVFA REMESGEVTA FILDKWAEGY SISEPWEKIG MHGGQLLDVY MKDVKVPADN LLGKIGQGFP ILLLGIALGK IGTSTAALGG TLAALEEASK YAREKTHRGQ PIAKFQAIQL KIADLAIKYE TARWLCYRLG CLANDIKDPG KFAAEAALVK AYCGDNVVDA ARIAVDVHGS YGLMRDYTIE RVYRDAIIGP EIEGVADMQK LIVASSILRS KG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 6-112 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF02770: 120-213 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF00441: 224-376 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
Sequence: MDFNLSKEQ SLIQQMAREF AEKSIAPVAK QIDEESKIPE EVLAGMAELD LFGIPFPEEY GGADGGYDGY VLAMEQIAKV SGGIAMTMAA HTLGLGAISA FGTEEQKKKY MIPGCKAKHI VSFAFTEPGT GSDPKQITTT AVKQGDFYIL NGTKRFISNA NYPGAMVVFA REMESGEVTA FILDKWAEGY SISEPWEKIG MHGGQLLDVY MKDVKVPADN LLGKIGQGFP ILLLGIALGK IGTSTAALGG TLAALEEASK YAREKTHRGQ PIAKFQAIQL KIADLAIKYE TARWLCYRLG CLANDIKDPG KFAAEAALVK AYCGDNVVDA ARIAVDVHGS YGLMRDYTIE RVYRDAIIGP EIEGVADMQK LIVASSILRS KG HMM: 51-235 GIPFPEEY GGADGGYDGY VLAMEQIAKV SGGIAMTMAA HTLGLGAISA FGTEEQKKKY MIPGCKAKHI VSFAFTEPGT GSDPKQITTT AVKQGDFYIL NGTKRFISNA NYPGAMVVFA REMESGEVTA FILDKWAEGY SISEPWEKIG MHGGQLLDVY MKDVKVPADN LLGKIGQGFP ILLLGIA ALI: 44-225 MAELD LFGIPFPEEY GGADGGYDGY VLAMEQIAKV SGGIAMTMAA HTLGLGAISA FGTEEQKKKY MIPGCKAKHI VSFAFTEPGT GSDPKQITTT AVKQGDFYIL NGTKRFISNA NYPGAMVVFA REMESGEVTA FILDKWAEGY SISEPWEKIG MHGGQLLDVY MKDVKVPADN LLGKIGQ ENV: 6-359 KEQ SLIQQMAREF AEKSIAPVAK QIDEESKIPE EVLAGMAELD LFGIPFPEEY GGADGGYDGY VLAMEQIAKV SGGIAMTMAA HTLGLGAISA FGTEEQKKKY MIPGCKAKHI VSFAFTEPGT GSDPKQITTT AVKQGDFYIL NGTKRFISNA NYPGAMVVFA REMESGEVTA FILDKWAEGY SISEPWEKIG MHGGQLLDVY MKDVKVPADN LLGKIGQGFP ILLLGIALGK IGTSTAALGG TLAALEEASK YAREKTHRGQ PIAKFQAIQL KIADLAIKYE TARWLCYRLG CLANDIKDPG KFAAEAALVK AYCGDNVVDA ARIAVDVHGS YGLMRDYTIE RVYRDAIIGP E Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDFRLNEEQ EMMKKMAHDF AVNEIAPYAS EWDNNHIYPE DCIKKMHEVG LMTIGVPAEY GGAGLDHTAQ NIVAEEICWG DAGVGTVMVA STLLASDPVL VAANHEQKKE FYGRLLDGEL AAFCLTEPGA GSDAGGIATR CVKSGDEYIL NGSKQFISNG GTAGVYTVLA TLDKKMGTKG MCAFIVDRNT PGITVGKTED KLGIRTSNTT EVIFEDVRVP AKNLLGTEGQ GFYIIMKTLD LSRASIAAMA TGVSQACLDA SLEYSKLRTQ FGKPICSFQA IQFKLADMAM RIEASRLLYL EASSLQDMNV PRFSKAASLA KAYAGDTAVF CATEAVQVFG GYGYTKDYPV EKYYRDAKIF QIYEGTGEVQ RLVIAGDLLR G
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 120-216 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 227-375 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
Sequence: MDFRLNEEQ EMMKKMAHDF AVNEIAPYAS EWDNNHIYPE DCIKKMHEVG LMTIGVPAEY GGAGLDHTAQ NIVAEEICWG DAGVGTVMVA STLLASDPVL VAANHEQKKE FYGRLLDGEL AAFCLTEPGA GSDAGGIATR CVKSGDEYIL NGSKQFISNG GTAGVYTVLA TLDKKMGTKG MCAFIVDRNT PGITVGKTED KLGIRTSNTT EVIFEDVRVP AKNLLGTEGQ GFYIIMKTLD LSRASIAAMA TGVSQACLDA SLEYSKLRTQ FGKPICSFQA IQFKLADMAM RIEASRLLYL EASSLQDMNV PRFSKAASLA KAYAGDTAVF CATEAVQVFG GYGYTKDYPV EKYYRDAKIF QIYEGTGEVQ RLVIAGDLLR G HMM: 51-285 TIGVPAEY GGAGLDHTAQ NIVAEEICWG DAGVGTVMVA STLLASDPVL VAANHEQKKE FYGRLLDGEL AAFCLTEPGA GSDAGGIATR CVKSGDEYIL NGSKQFISNG GTAGVYTVLA TLDKKMGTKG MCAFIVDRNT PGITVGKTED KLGIRTSNTT EVIFEDVRVP AKNLLGTEGQ GFYIIMKTLD LSRASIAAMA TGVSQACLDA SLEYSKLRTQ FGKPICSFQA IQFKLAD ALI: 44-272 MHEVG LMTIGVPAEY GGAGLDHTAQ NIVAEEICWG DAGVGTVMVA STLLASDPVL VAANHEQKKE FYGRLLDGEL AAFCLTEPGA GSDAGGIATR CVKSGDEYIL NGSKQFISNG GTAGVYTVLA TLDKKMGTKG MCAFIVDRNT PGITVGKTED KLGIRTSNTT EVIFEDVRVP AKNLLGTEGQ GFYIIMKTLD LSRASIAAMA TGVSQACLDA SLEYSKLRTQ FGKP ENV: 30-367 WDNNHIYPE DCIKKMHEVG LMTIGVPAEY GGAGLDHTAQ NIVAEEICWG DAGVGTVMVA STLLASDPVL VAANHEQKKE FYGRLLDGEL AAFCLTEPGA GSDAGGIATR CVKSGDEYIL NGSKQFISNG GTAGVYTVLA TLDKKMGTKG MCAFIVDRNT PGITVGKTED KLGIRTSNTT EVIFEDVRVP AKNLLGTEGQ GFYIIMKTLD LSRASIAAMA TGVSQACLDA SLEYSKLRTQ FGKPICSFQA IQFKLADMAM RIEASRLLYL EASSLQDMNV PRFSKAASLA KAYAGDTAVF CATEAVQVFG GYGYTKDYPV EKYYRDAKIF QIYEGTGEV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MNFNYTEEQ LMLKESVRKF SENEIAPLVK WMETEKRTPW DLIKKIKDLG WCGIQYPEKY GGSGNTYVEY VIMQIEMARV YCSTACTISV NGMLGANIMK FATEEQKMKF LPEHLNGDGI GSFAFTEAST GSDPNALRTT CVRDGDEWVI NGEKVFITNA SLPGLMGIFC KDVEMGGKCT NILIPKGIKG YSIPRIYDKM GMHGLEVCDV LLDNVRVPYE NTTGGEAMRG KGFEVLLGST QIGKLSVCAQ AVGMAQAALE AAVKYSKERV QRGKPIAYFP TIQSLIGDMA TDVMVAHQAV LATAFKASEG KELASDAART RLFTSEAVHR VASKAMQVMG AYSYTTEFPI ERIFRDAKLT EIYEGVNEIQ RLIAAADLLR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-117 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 120-214 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF00441: 228-377 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MNFNYTEEQ LMLKESVRKF SENEIAPLVK WMETEKRTPW DLIKKIKDLG WCGIQYPEKY GGSGNTYVEY VIMQIEMARV YCSTACTISV NGMLGANIMK FATEEQKMKF LPEHLNGDGI GSFAFTEAST GSDPNALRTT CVRDGDEWVI NGEKVFITNA SLPGLMGIFC KDVEMGGKCT NILIPKGIKG YSIPRIYDKM GMHGLEVCDV LLDNVRVPYE NTTGGEAMRG KGFEVLLGST QIGKLSVCAQ AVGMAQAALE AAVKYSKERV QRGKPIAYFP TIQSLIGDMA TDVMVAHQAV LATAFKASEG KELASDAART RLFTSEAVHR VASKAMQVMG AYSYTTEFPI ERIFRDAKLT EIYEGVNEIQ RLIAAADLLR HMM: 52-283 IQYPEKY GGSGNTYVEY VIMQIEMARV YCSTACTISV NGMLGANIMK FATEEQKMKF LPEHLNGDGI GSFAFTEAST GSDPNALRTT CVRDGDEWVI NGEKVFITNA SLPGLMGIFC KDVEMGGKCT NILIPKGIKG YSIPRIYDKM GMHGLEVCDV LLDNVRVPYE NTTGGEAMRG KGFEVLLGST QIGKLSVCAQ AVGMAQAALE AAVKYSKERV QRGKPIAYFP TIQSL ALI: 45-271 KDLG WCGIQYPEKY GGSGNTYVEY VIMQIEMARV YCSTACTISV NGMLGANIMK FATEEQKMKF LPEHLNGDGI GSFAFTEAST GSDPNALRTT CVRDGDEWVI NGEKVFITNA SLPGLMGIFC KDVEMGGKCT NILIPKGIKG YSIPRIYDKM GMHGLEVCDV LLDNVRVPYE NTTGGEAMRG KGFEVLLGST QIGKLSVCAQ AVGMAQAALE AAVKYSKERV QRG ENV: 40-368 LIKKIKDLG WCGIQYPEKY GGSGNTYVEY VIMQIEMARV YCSTACTISV NGMLGANIMK FATEEQKMKF LPEHLNGDGI GSFAFTEAST GSDPNALRTT CVRDGDEWVI NGEKVFITNA SLPGLMGIFC KDVEMGGKCT NILIPKGIKG YSIPRIYDKM GMHGLEVCDV LLDNVRVPYE NTTGGEAMRG KGFEVLLGST QIGKLSVCAQ AVGMAQAALE AAVKYSKERV QRGKPIAYFP TIQSLIGDMA TDVMVAHQAV LATAFKASEG KELASDAART RLFTSEAVHR VASKAMQVMG AYSYTTEFPI ERIFRDAKLT EIYEGVNEIQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
PF02901: 3-588 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF01228: 604-710 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 510-580 LSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TI ALI: 409-479 RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY A ENV: 389-507 GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 662-846 LLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM ALI: 538-724 P KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTF ENV: 525-727 RGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 297-431 EY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQ ALI: 221-353 RPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRN ENV: 177-362 EN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 490-552 TFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAV ALI: 418-480 Y AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AY ENV: 400-517 GKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 633-817 ARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM ALI: 538-724 P KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTF ENV: 530-727 DFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 272-428 TENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS ALI: 204-361 SLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEF ENV: 192-369 IQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS T Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 490-561 TFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQ ALI: 408-480 A RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AY ENV: 391-497 ACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MHEIDVRDF IQKNYSPYDG DSGFLTGPGE KTSLLWRKCQ DLLQKERESK GVLLVDADTP LSITSHPPGY IDRELEKIIG LQTDKALKRA INVYGGLKMT LNACRAYGYE PDKKLLKFFE KHRRTHNDGV FAVYTPEMRL ARKVGIITGL PDSYGRGRII GDCRRVSLYG VDFLIKAKEN DRDWLNRRMT PELIQLREDM AGQIKSLQDL KQMAKSYDYD ISRPAATAVE AVQHLYFAYL AAVKEQNGAA MSLGRVSTFL DIYLERDLRL GRITENEAQE LIDQLVIKLR LVRHLRTPEY SEIFAGDPNW VTESLGGSGT DGRHLVSKTS YRFLQTLKNL GAAPEPNMTI LWSRNLPRNF LEFCAKLSIS TSALQYENDD LMRDYYGDDY GIACCVSAMR LGKETQLFGA RCNLAKLLLY AINGGKDEIS GQQVGVEMSV YDGDRLEFGE VMRRFKIQME WLAELYVNTM NLIHYMHDKY AYEYVQMALH NTFVKHFMAF GIAGLSVAAD SLSAIKYAKV RPIKDERGLV SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM HMM: 644-830 VPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRRM ALI: 538-725 P KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFY ENV: 529-727 SDFAIEGEFP KFGNDDDRVD LLAVEIIHTF IHQLKRHPAY RDAQHTLSIL TITSNVMYGK YTGTTPDGRQ KGEPLAPGAN PLHGREEKGA IAACNSVAKL PYEDARDGIS FTFSTVPEAL GKSKEERVNN LLALLEGYFV QDAHHMNVNV LNVETLKEAM EHPEKYPDLT IRVSGYAVHF TKLNREQQEE IIMRTFYRR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
PF00384: 2-332 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF01568: 414-520 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 251-311 VSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRK ALI: 36-96 VRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEA ENV: 17-102 IG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 392-462 GLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGE ALI: 105-175 EKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVN ENV: 97-184 YE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 610-679 ALI: 265-332 NLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTR ENV: 231-337 INKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 820-894 ALI: 411-486 EYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKEN ENV: 401-508 FQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 246-330 GEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LS ALI: 11-96 ATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEA ENV: 7-99 LE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 408-481 P DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTD ALI: 103-177 VVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPL ENV: 96-185 AYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 592-700 ALI: 231-335 INKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGY ENV: 187-341 CD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 841-921 ALI: 412-493 YPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFH ENV: 402-506 QEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNAS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 253-313 DPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAI ALI: 35-95 NVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTE ENV: 26-97 PVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 385-470 HKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RR ALI: 96-183 AYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNV ENV: 91-193 ETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 610-684 ALI: 262-334 ALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLG ENV: 257-356 DH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAIGELE KDATAIFLIG TNTTENHPVI GYKIRKNVRE NGAKLIVADP REIELAGIAD VYMQFRPGTD VALLNGMMNV IINEGLLDKE FVETRTEAYE AFAQVVEKYT PEYVSPITGV PAEDIRKAAR IYAEAERASI CYAMGLTQHS TGTDNVKSCC NLALLTGNLG KPGTGVNPLR GQNNVQGACD MGALPVVFTA YQGVGIEANR EKFEKAWGVK LSGQNGLTLT AAINKAHHGE LKALLVLGEN PMVSDPDLDH VEDALDNLEF LMVQDIFLTE TAQRADVVFP GVTFAEKEGT FTNTERRVQR VRKAISNRGD ARQDYEILCE LSTRLGYPMS YSSPEEIFEE IRTLTPSYAG ITYQRLEGKG LHWPCPTEDH PGTPILHKEK FNRGLGLFHA IEFQEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA ANMLTNASVL DPVAGIPEYK VSAARLEKIS HMM: 838-912 ALI: 412-487 YPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENV ENV: 402-498 QEAAELP DAEYPLILST GRSLFHYHTG TMTRRAVALD LHQPENEIQV NPVTAAKLGI MDGEMARVVT RRGSIELKAK LTDIVKENVI FTFFHFSEAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
PF00384: 8-436 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
PF01568: 683-801 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 213-311 IRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNN ALI: 5-103 GRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNA ENV: 2-114 PSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 383-465 KIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEAS ALI: 155-237 VFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALR ENV: 144-247 VKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 838-894 ALI: 698-753 T RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTL ENV: 660-800 VQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 231-330 GGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QF ALI: 4-103 FGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNA ENV: 1-112 SPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 400-481 AGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATG ALI: 155-236 VFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQAL ENV: 135-251 YQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 649-700 ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RN ALI: 390-439 FLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR T ENV: 377-446 EG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSND Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 215-313 CYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPA ALI: 4-102 FGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTN ENV: 2-113 PSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 385-480 PTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND AT ALI: 155-250 VFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM AN ENV: 139-283 AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSPSFGRGA MTNSWQDMQN SECFLIAGSN CAECHPIAMK WVNRARAKGA KVIVVDPRFT RTASQADIFA QIRPGTDIAY LGAMINYYIE NRLYDEFYVL NFTNALNKIS KDYQFNDGLF SGFNPETRKY DYASWAYQLD AEGKPVKADS LDDPDCVFQK LKTHYSRYTF DAASKITGIP VAKIKLIADT FAAAKPGNIF YALGMTQHTT GVQGIRCYAI IQLLLGNVGK AGGGIQALRG EPNVQGSTDM ANLNANLPGY LPYPTNAEKT LQDYVAKNGS VQHKPLVALL KAWFGNNATP ENEYGYQWLP KNNPANMPIQ PQFFSKMEEG QFKLLLNWGS NSTVSIPDRK LVSRGLSKLE MLVVADIFNT ETAQFWKEEG LNPAKIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YGEHEASALK VLQELNGYND ATGKLTASLG EYLAAPVGTI STGCWIYAGV TPDVDKNLAD RRGNADPTGL GLNKDYAFAW PGNIRVLYNR ASCDAQGQPV DSRRKLIWWD PIQNLWVGND GPDVVDKTKG PDTPEGKQAF RMNPEGVGRL FAATYKSGTF ATPPEGIAAV PIRGAGMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYGV VEHFCAGAIT RNIPWLNEIA PEPYAEISKN LAKQIGVKEG DKVEVSSARG SLVVRALVTD RIQTLKINGK DQETIGMPWS WGFASLNPGP STNNVTMNAC DPGAGTPEYK CCLVNIRRA HMM: 634-687 GMTID GPMPEFYEPI ESPVANLLHP AVQNNPCAKI VSKEFGNPDE YPHVLTTYG ALI: 390-441 FLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLY ENV: 383-460 KIPTEV IFLPAAFVYE KAGSMTNSSR LIQWKEVALK PLNDCHPDLD MLDHIFKRVR TLYAGSNDPK DEPILKANWD YG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
PF00384: 429-475 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF01568: 718-835 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 243-464 DMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKAD ALI: 27-232 SM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNAL ENV: 5-247 VDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 632-681 GDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEP ALI: 429-476 LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVK ENV: 389-502 VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 831-898 YKAWLCDI RRA ALI: 725-795 HWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVH ENV: 705-816 DKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 248-481 F HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAG ALI: 12-232 CALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNAL ENV: 5-248 VDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 650-701 TGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKV ALI: 429-478 LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL ENV: 422-486 IQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 875-908 ALI: 748-781 E LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVT ENV: 745-787 MMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 247-465 LF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADL ALI: 27-230 SM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VN ENV: 3-250 HIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARETR GAKIIHVDPR FTRTSARSDI YCPMRSGTDI AFLGGMIKYI IDNELYHKDY VVHYTNASFL VKEEFGFEDG LFTGYDAEKR KYDVSSWDYQ VDEAGLPLTD PTLQDPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL NTYCATGAPD KTGNIMYAMG ITQHTVGSQN VRSFAMVQLL LGNMGRPGGG VNALRGENNV QGATDMALLF HIIPGYIDSP MNTAANKDLL SFIRAQTPGA AKLPFTNLEE FRALVKAGFP NSGFKINTSK WVISLLKAWW GKAATADNDF GYHYLPKRDG NKNYSHIALF EAMHRGEIDG LFVNGTNPVV GGPNANKEQE ALTKLKWMVS VDLWLNETAD YWTYQGWERT VKNPNVPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DENGHDDIMK VALELCGYNV ADGKPVEGFA KLSDDGSTAC GCWVYCGAMT YKDGKIIYKT QNRDNKDNSK TGLGLFSNWA WAWPMNRRIV YNRCSVQPDG MTPWPGDADR QLIRWDPTIP ADPKKPEALG SWVGDDVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTEN IMNKQNLNPA TKVWEPDKQG TSDKYPIIGT TYRVVEHWQT GALTRNLPWL AELMPDMMVE LSEQLAKERG IKNGHKVIIS TTRGDIEAVA CVTKRFKPFI VNGKTVHEIG LLWHYGFKGY ATGDPANRLT PHIGDANTMI PEYKAWLCDI RRA HMM: 634-687 DVPDF LKPTSPDKPA FTGPFIMRPE LKGCLFAPKS AMKDGPFPEH YEPWESPTE ALI: 428-479 F LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL Y ENV: 414-500 VPTYT PADIQTEVFF LPAAAVYEKE GTAAQTGRWV QFRWKGADPV GESKADLWIY NELGKRVKKL YAGSTKPQDE PIVNLDWNYD DE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
PF00384: 1-301 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
PF01568: 400-504 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 251-311 LEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TIC ALI: 21-81 AARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TEN ENV: 3-93 IGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 389-462 PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKV ALI: 87-160 AI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VC ENV: 82-164 YEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 591-641 ALI: 232-281 ENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECD ENV: 193-311 REKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TIC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 860-908 ALI: 435-478 DADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ENV: 429-500 SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 256-330 VQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IW ALI: 7-81 PT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TEN ENV: 1-82 FLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 403-480 TGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN AT ALI: 84-161 ELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCP ENV: 81-170 NYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 601-696 ALI: 225-315 KAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFV ENV: 173-324 DMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 877-915 ALI: 432-470 NPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GV ENV: 428-480 M SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN AT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 254-314 LVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMF ALI: 21-81 AARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TEN ENV: 7-82 PT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 386-470 HIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GV ALI: 82-168 YEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV ENV: 79-180 TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 612-675 ALI: 249-309 EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ T ENV: 240-319 DANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG Y Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MFLIGTNPT EAHPVIGYKM RQAARRGAKL VVCDPRHIDL VDEADYWLRV KPGTDIPLLN GLMHIIIKEG LEDKTFIEER TENYEELKAI VESYTPERVS ELTGISVDDL YAVARLYATT DKAMIFYTLG ITEHICGTRN VMSCANLAML TGHLGRPGTG VCPQRGQNNV QGACDMGALP NVYSGYQAVG VDAVREKHEK AWKASLSAKV GLKIPEMFGA AHEGKVKAMY ILGENPVLTD PDANHIRGAL EKLEFLVVQE LFLTETAAYA DVILPAASFA ECDGTFTNTE RRVQRVRKAI EPIPGQANWQ TICQMFVAMG YPVNYNSPKE IWDEMASLSP SMAGINFERI DQENSLQWPC PSLDHPGTPV LHVGKFTRGL GLFQPSEHIP PGEIPDAEYP YLLSTGRILQ HYNVTTPYSK GISSIWDKEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTNALTSH HLDPITGTGE YKVCAVKLEK V HMM: 874-915 ALI: 432-473 NPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWM ENV: 426-483 KEM SELNPVDADK LGVVTGDQVK VTSRRGEAIT QIKVTDRVLP GVIWMSFHYN ATPTN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
PF00384: 9-327 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF01568: 413-518 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 251-311 TDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKA ALI: 35-95 AARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTEN ENV: 11-105 AELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVEN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 389-464 TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVT ALI: 101-176 ATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPI ENV: 95-251 NYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 585-641 ALI: 240-295 AMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECD ENV: 219-331 PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 857-908 ALI: 446-492 NPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYS ENV: 411-516 YPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 245-330 GENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SR ALI: 10-95 DAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTEN ENV: 4-96 ISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 402-480 PPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RV ALI: 97-175 EA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCP ENV: 94-198 ENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 629-700 ALI: 265-333 LEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGY ENV: 229-337 MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 874-917 ALI: 443-486 AELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIW ENV: 407-498 PD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 254-314 NSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEP ALI: 35-95 AARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTEN ENV: 12-96 ELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 386-471 GKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVV ALI: 96-183 YEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQ ENV: 93-197 TENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 615-681 ALI: 266-330 EFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SR ENV: 258-343 I RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNAISEIT TDAELLFLIG TNTTEAHPVT GYKMRQAARR GCKLVVCDPR HIDLVDEADY WLRQKPGTDI PLINGLMHII IKEGLEDKKF IEERTENYEA LKATVENYPP EYVAELTGIP VDVLYEVARL YATTDRAMIF YTLGITEHIC GTRNVMSLAN LAMLTGHMGR AGVGVCPIRG QNNVQGACDM GALPNVYQGY QNVTLPAVKE KFEKAWGRPM PDKIGLKIPE MFEAAHEGKV KAMYILGENP VLTDPNSHHI RGGLEALEFL VVQELFLTET AEYADVILPA ASFAECDGTF SNTERRVQRV RKAIEPIPGR ANWQTICEMV SRMGYPMNYE SPREIWDEMA SLAPSMTGIN YDRLEELGSL QWPCPSTDHP GTQFMHVGKF TRGLGLFQPS DHIPPGEMPD EEYPFLLSTG RILQHYNVTT PYSKGIMSVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTNA LTSHHLDPIT GTGEYKVCAV KLEKI HMM: 874-915 ALI: 446-487 NPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWM ENV: 436-497 SVW NKEMAELNPA DAEKMGVKTG DKLKVTSRRG EVVTAVRVTD RVMPGIIWMS FHYSETPTN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
PF04879: 43-95 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00384: 98-135 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI HMM: 97-160 ER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EG ALI: 73-134 PDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDK ENV: 56-150 GLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI HMM: 20-33 SGLGFDLEA TAAHG ALI: 3-16 TRRGFL KLSGLSVA ENV: 2-30 FTRRGFL KLSGLSVAVV ASGLGFDLEA TA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI HMM: 124-181 IAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLA ALI: 81-136 TLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTW ENV: 63-161 DGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI HMM: 4-27 RRGFL KLSGLSVAVV ASGLGFDLE ALI: 1-23 KFTRRGFL KLSGLSVAVV ASGLG ENV: 1-40 KFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MKFTRRGFL KLSGLSVAVV ASGLGFDLEA TAAHGHALKL AGCTKIPSIC HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI HMM: 104-202 YRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KLARLIGTPF HEHQARI ALI: 77-173 IN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEE ENV: 49-180 HFCSGGCGLL LHIKDGKLVH LDGNPDNPIN EGTLCPKAAS LAQVAYSPER PKNPLYRAPG SDKFVDISWE EAYDRIAKKI KEVRDKTWTS TEEITNAKTG AKETVTVNRA EGICMIGSAE VDNEESYLLS KL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
PF04879: 45-99 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI HMM: 115-154 KRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNF ALI: 109-146 EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKI ENV: 85-160 NQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI HMM: 19-46 ALVDLGFDLQ ATASAAKELR IKNVTPTP ALI: 2-29 VTRRQFL KVTGATAASF ALVDLGFDLQ A ENV: 1-48 KVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI HMM: 127-178 SD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG ALI: 91-151 SKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRD ENV: 60-162 IYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLED Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI HMM: 4-36 RRQFL KVTGATAASF ALVDLGFDLQ ATASAAKE ALI: 1-34 KVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAA ENV: 1-44 KVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MKVTRRQFL KVTGATAASF ALVDLGFDLQ ATASAAKELR IKNVTPTPTV CPYCASGCGL VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQARI HMM: 118-165 Q KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSE ALI: 109-154 EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNF ENV: 59-206 VIYAERDANG NFVKLLSVHG DPDNPINQGG ACSKGAAMFN LREIYDERTG EQMINPKRVQ KPLYRAPGSD KWEEKDWDWM LDRIAEKIKE TRDSNFIHKE KLEDGSEIIV NRTERIASIG GSGLDNEECY ILSKMMRALG VVYLETQA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MNFMLSEEQ ELIRSNAREF ALKYIEPVAT KIDQESRHPV EVFDKLAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQWFIANMA TDIDAARFLY MNAAFIKDQG KPFSVAASKA KLFCSECAAR HTTKAVQIQG GYGFMKGAKV ERFYRDVKLT EIGEGTSEAQ RMIIAGSVLR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-217 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 228-377 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MNFMLSEEQ ELIRSNAREF ALKYIEPVAT KIDQESRHPV EVFDKLAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQWFIANMA TDIDAARFLY MNAAFIKDQG KPFSVAASKA KLFCSECAAR HTTKAVQIQG GYGFMKGAKV ERFYRDVKLT EIGEGTSEAQ RMIIAGSVLR HMM: 44-293 LAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQWFIANMA TDIDA ALI: 37-281 PV EVFDKLAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQ ENV: 9-288 ELIRSNAREF ALKYIEPVAT KIDQESRHPV EVFDKLAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQWFIANMA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MNFMLSEEQ ELIRSNAREF ALKYIEPVAT KIDQESRHPV EVFDKLAELD MMGISYPSEY GGGGAEFLTT MIVTEELARS CATTGFLHGY SYGLIGHPIL TFGNEEQKQK WMPGLAAGKL VGSFALTEPG AGTDVSSATT TAVKKGDKYI LNGTKTFITN AILADVFVVF AYTDRSAGAK GMSCFLVPQG SSGLNVGQHF DKMGVRGSQT SEVVFKDCVV AADCMLGKEG DGFKIAMSAL DVGRIGIAAM STGITQGCLD ESIKYSKERV QFKKPIASQQ AIQWFIANMA TDIDAARFLY MNAAFIKDQG KPFSVAASKA KLFCSECAAR HTTKAVQIQG GYGFMKGAKV ERFYRDVKLT EIGEGTSEAQ RMIIAGSVLR HMM: 343-387 MKGAKV ERFYRDVKLT EIGEGTSEAQ RMIIAGSVLR ALI: 314-358 AASKA KLFCSECAAR HTTKAVQIQG GYGFMKGAKV ERFYRDVKLT ENV: 302-364 AFIKDQG KPFSVAASKA KLFCSECAAR HTTKAVQIQG GYGFMKGAKV ERFYRDVKLT EIGEGT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MDFALSDES LMMRDMFRKF SKNEVEPLAA EIDRTHEFPM TTFKKMADLG LTGLPIPEEW GGAGASYLDF AMFVEELAKC CASTAVIMSV HTGLGCMSTY LYGSQRVKEK YLRALATGEI VGAYALTEPN AGSDAASLKC KAEDKGDYFL VNGSKIFITN GGVATTYCTF VKSDPSQGSG RGITCLVIEK DTPGFTMSKP VAKMGMNGSP TVELYFEDVK VPKENVLGEI NDGFKVAMGL LAGGRVTIAA QGLGIGEGAL DYTVQYIKER QQFGKPLAAN QGVQFMVADM AAALDAAQLL VYRAAWLKDN GLPHNKEASM AKKFATDTGM EVCTNCVQLM GGYGYCNEFP VERMMRDVKI TQIYEGSNQI QRMIIGRETI GRF
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-218 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 229-377 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MDFALSDES LMMRDMFRKF SKNEVEPLAA EIDRTHEFPM TTFKKMADLG LTGLPIPEEW GGAGASYLDF AMFVEELAKC CASTAVIMSV HTGLGCMSTY LYGSQRVKEK YLRALATGEI VGAYALTEPN AGSDAASLKC KAEDKGDYFL VNGSKIFITN GGVATTYCTF VKSDPSQGSG RGITCLVIEK DTPGFTMSKP VAKMGMNGSP TVELYFEDVK VPKENVLGEI NDGFKVAMGL LAGGRVTIAA QGLGIGEGAL DYTVQYIKER QQFGKPLAAN QGVQFMVADM AAALDAAQLL VYRAAWLKDN GLPHNKEASM AKKFATDTGM EVCTNCVQLM GGYGYCNEFP VERMMRDVKI TQIYEGSNQI QRMIIGRETI GRF HMM: 35-391 EFPM TTFKKMADLG LTGLPIPEEW GGAGASYLDF AMFVEELAKC CASTAVIMSV HTGLGCMSTY LYGSQRVKEK YLRALATGEI VGAYALTEPN AGSDAASLKC KAEDKGDYFL VNGSKIFITN GGVATTYCTF VKSDPSQGSG RGITCLVIEK DTPGFTMSKP VAKMGMNGSP TVELYFEDVK VPKENVLGEI NDGFKVAMGL LAGGRVTIAA QGLGIGEGAL DYTVQYIKER QQFGKPLAAN QGVQFMVADM AAALDAAQLL VYRAAWLKDN GLPHNKEASM AKKFATDTGM EVCTNCVQLM GGYGYCNEFP VERMMRDVKI TQIYEGSNQI QRMIIGRETI GRF ALI: 28-363 A EIDRTHEFPM TTFKKMADLG LTGLPIPEEW GGAGASYLDF AMFVEELAKC CASTAVIMSV HTGLGCMSTY LYGSQRVKEK YLRALATGEI VGAYALTEPN AGSDAASLKC KAEDKGDYFL VNGSKIFITN GGVATTYCTF VKSDPSQGSG RGITCLVIEK DTPGFTMSKP VAKMGMNGSP TVELYFEDVK VPKENVLGEI NDGFKVAMGL LAGGRVTIAA QGLGIGEGAL DYTVQYIKER QQFGKPLAAN QGVQFMVADM AAALDAAQLL VYRAAWLKDN GLPHNKEASM AKKFATDTGM EVCTNCVQLM GGYGYCNEFP VERMMRDVKI TQIYE ENV: 2-378 FALSDES LMMRDMFRKF SKNEVEPLAA EIDRTHEFPM TTFKKMADLG LTGLPIPEEW GGAGASYLDF AMFVEELAKC CASTAVIMSV HTGLGCMSTY LYGSQRVKEK YLRALATGEI VGAYALTEPN AGSDAASLKC KAEDKGDYFL VNGSKIFITN GGVATTYCTF VKSDPSQGSG RGITCLVIEK DTPGFTMSKP VAKMGMNGSP TVELYFEDVK VPKENVLGEI NDGFKVAMGL LAGGRVTIAA QGLGIGEGAL DYTVQYIKER QQFGKPLAAN QGVQFMVADM AAALDAAQLL VYRAAWLKDN GLPHNKEASM AKKFATDTGM EVCTNCVQLM GGYGYCNEFP VERMMRDVKI TQIYEGSNQI QRMIIGRETI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDFKLSEEQ ELIRENIREL VKKYLDPIAV EIDESSRYPA EVIEQLAAGG WMGMPYPVEY GGAGLDYVSY AMVIEEISRS CAATGFTVSC HTSLASGPIF NFGNEEQKQK YLVPLAKGQH IGAFAVTEPG AGTDVGAATT TATLDGDSYV LNGIKTFTSN GPVADTFVVF AFTDKSLGGK GMSAFIISKD NPGLKVGQHF YKMGIRASQT SEIILKDCRV PREDLLGKEG QGLQIAMSSF DHGRIGIAAQ AVGITQAALD ESISYSKQRV QFGKPISKNQ AIQWMIADMA TDIAAARFLY SYAAFLKDQK QPFSKEAAMA KVFAAEMSTR HTSKAVQIHG GYGYIKGQKV ERLMRDAKIT EIYEGTSEAQ RMVIAGNLLR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-217 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 228-377 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MDFKLSEEQ ELIRENIREL VKKYLDPIAV EIDESSRYPA EVIEQLAAGG WMGMPYPVEY GGAGLDYVSY AMVIEEISRS CAATGFTVSC HTSLASGPIF NFGNEEQKQK YLVPLAKGQH IGAFAVTEPG AGTDVGAATT TATLDGDSYV LNGIKTFTSN GPVADTFVVF AFTDKSLGGK GMSAFIISKD NPGLKVGQHF YKMGIRASQT SEIILKDCRV PREDLLGKEG QGLQIAMSSF DHGRIGIAAQ AVGITQAALD ESISYSKQRV QFGKPISKNQ AIQWMIADMA TDIAAARFLY SYAAFLKDQK QPFSKEAAMA KVFAAEMSTR HTSKAVQIHG GYGYIKGQKV ERLMRDAKIT EIYEGTSEAQ RMVIAGNLLR HMM: 24-293 DPIAV EIDESSRYPA EVIEQLAAGG WMGMPYPVEY GGAGLDYVSY AMVIEEISRS CAATGFTVSC HTSLASGPIF NFGNEEQKQK YLVPLAKGQH IGAFAVTEPG AGTDVGAATT TATLDGDSYV LNGIKTFTSN GPVADTFVVF AFTDKSLGGK GMSAFIISKD NPGLKVGQHF YKMGIRASQT SEIILKDCRV PREDLLGKEG QGLQIAMSSF DHGRIGIAAQ AVGITQAALD ESISYSKQRV QFGKPISKNQ AIQWMIADMA TDIAA ALI: 16-281 REL VKKYLDPIAV EIDESSRYPA EVIEQLAAGG WMGMPYPVEY GGAGLDYVSY AMVIEEISRS CAATGFTVSC HTSLASGPIF NFGNEEQKQK YLVPLAKGQH IGAFAVTEPG AGTDVGAATT TATLDGDSYV LNGIKTFTSN GPVADTFVVF AFTDKSLGGK GMSAFIISKD NPGLKVGQHF YKMGIRASQT SEIILKDCRV PREDLLGKEG QGLQIAMSSF DHGRIGIAAQ AVGITQAALD ESISYSKQRV QFGKPISKNQ AIQ ENV: 6-317 EEQ ELIRENIREL VKKYLDPIAV EIDESSRYPA EVIEQLAAGG WMGMPYPVEY GGAGLDYVSY AMVIEEISRS CAATGFTVSC HTSLASGPIF NFGNEEQKQK YLVPLAKGQH IGAFAVTEPG AGTDVGAATT TATLDGDSYV LNGIKTFTSN GPVADTFVVF AFTDKSLGGK GMSAFIISKD NPGLKVGQHF YKMGIRASQT SEIILKDCRV PREDLLGKEG QGLQIAMSSF DHGRIGIAAQ AVGITQAALD ESISYSKQRV QFGKPISKNQ AIQWMIADMA TDIAAARFLY SYAAFLKDQK QPFSKEAAM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MDFNLSKEQ SLIQQMAREF AEKSIAPVAK QIDEESKIPE EVLAGMAELD LFGIPFPEEY GGADGGYDGY VLAMEQIAKV SGGIAMTMAA HTLGLGAISA FGTEEQKKKY MIPGCKAKHI VSFAFTEPGT GSDPKQITTT AVKQGDFYIL NGTKRFISNA NYPGAMVVFA REMESGEVTA FILDKWAEGY SISEPWEKIG MHGGQLLDVY MKDVKVPADN LLGKIGQGFP ILLLGIALGK IGTSTAALGG TLAALEEASK YAREKTHRGQ PIAKFQAIQL KIADLAIKYE TARWLCYRLG CLANDIKDPG KFAAEAALVK AYCGDNVVDA ARIAVDVHGS YGLMRDYTIE RVYRDAIIGP EIEGVADMQK LIVASSILRS KG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 6-112 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF02770: 120-213 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF00441: 224-376 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
Sequence: MDFNLSKEQ SLIQQMAREF AEKSIAPVAK QIDEESKIPE EVLAGMAELD LFGIPFPEEY GGADGGYDGY VLAMEQIAKV SGGIAMTMAA HTLGLGAISA FGTEEQKKKY MIPGCKAKHI VSFAFTEPGT GSDPKQITTT AVKQGDFYIL NGTKRFISNA NYPGAMVVFA REMESGEVTA FILDKWAEGY SISEPWEKIG MHGGQLLDVY MKDVKVPADN LLGKIGQGFP ILLLGIALGK IGTSTAALGG TLAALEEASK YAREKTHRGQ PIAKFQAIQL KIADLAIKYE TARWLCYRLG CLANDIKDPG KFAAEAALVK AYCGDNVVDA ARIAVDVHGS YGLMRDYTIE RVYRDAIIGP EIEGVADMQK LIVASSILRS KG HMM: 51-235 GIPFPEEY GGADGGYDGY VLAMEQIAKV SGGIAMTMAA HTLGLGAISA FGTEEQKKKY MIPGCKAKHI VSFAFTEPGT GSDPKQITTT AVKQGDFYIL NGTKRFISNA NYPGAMVVFA REMESGEVTA FILDKWAEGY SISEPWEKIG MHGGQLLDVY MKDVKVPADN LLGKIGQGFP ILLLGIA ALI: 44-225 MAELD LFGIPFPEEY GGADGGYDGY VLAMEQIAKV SGGIAMTMAA HTLGLGAISA FGTEEQKKKY MIPGCKAKHI VSFAFTEPGT GSDPKQITTT AVKQGDFYIL NGTKRFISNA NYPGAMVVFA REMESGEVTA FILDKWAEGY SISEPWEKIG MHGGQLLDVY MKDVKVPADN LLGKIGQ ENV: 6-359 KEQ SLIQQMAREF AEKSIAPVAK QIDEESKIPE EVLAGMAELD LFGIPFPEEY GGADGGYDGY VLAMEQIAKV SGGIAMTMAA HTLGLGAISA FGTEEQKKKY MIPGCKAKHI VSFAFTEPGT GSDPKQITTT AVKQGDFYIL NGTKRFISNA NYPGAMVVFA REMESGEVTA FILDKWAEGY SISEPWEKIG MHGGQLLDVY MKDVKVPADN LLGKIGQGFP ILLLGIALGK IGTSTAALGG TLAALEEASK YAREKTHRGQ PIAKFQAIQL KIADLAIKYE TARWLCYRLG CLANDIKDPG KFAAEAALVK AYCGDNVVDA ARIAVDVHGS YGLMRDYTIE RVYRDAIIGP E Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDFRLNEEQ EMMKKMAHDF AVNEIAPYAS EWDNNHIYPE DCIKKMHEVG LMTIGVPAEY GGAGLDHTAQ NIVAEEICWG DAGVGTVMVA STLLASDPVL VAANHEQKKE FYGRLLDGEL AAFCLTEPGA GSDAGGIATR CVKSGDEYIL NGSKQFISNG GTAGVYTVLA TLDKKMGTKG MCAFIVDRNT PGITVGKTED KLGIRTSNTT EVIFEDVRVP AKNLLGTEGQ GFYIIMKTLD LSRASIAAMA TGVSQACLDA SLEYSKLRTQ FGKPICSFQA IQFKLADMAM RIEASRLLYL EASSLQDMNV PRFSKAASLA KAYAGDTAVF CATEAVQVFG GYGYTKDYPV EKYYRDAKIF QIYEGTGEVQ RLVIAGDLLR G
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 120-216 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 227-375 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
Sequence: MDFRLNEEQ EMMKKMAHDF AVNEIAPYAS EWDNNHIYPE DCIKKMHEVG LMTIGVPAEY GGAGLDHTAQ NIVAEEICWG DAGVGTVMVA STLLASDPVL VAANHEQKKE FYGRLLDGEL AAFCLTEPGA GSDAGGIATR CVKSGDEYIL NGSKQFISNG GTAGVYTVLA TLDKKMGTKG MCAFIVDRNT PGITVGKTED KLGIRTSNTT EVIFEDVRVP AKNLLGTEGQ GFYIIMKTLD LSRASIAAMA TGVSQACLDA SLEYSKLRTQ FGKPICSFQA IQFKLADMAM RIEASRLLYL EASSLQDMNV PRFSKAASLA KAYAGDTAVF CATEAVQVFG GYGYTKDYPV EKYYRDAKIF QIYEGTGEVQ RLVIAGDLLR G HMM: 51-285 TIGVPAEY GGAGLDHTAQ NIVAEEICWG DAGVGTVMVA STLLASDPVL VAANHEQKKE FYGRLLDGEL AAFCLTEPGA GSDAGGIATR CVKSGDEYIL NGSKQFISNG GTAGVYTVLA TLDKKMGTKG MCAFIVDRNT PGITVGKTED KLGIRTSNTT EVIFEDVRVP AKNLLGTEGQ GFYIIMKTLD LSRASIAAMA TGVSQACLDA SLEYSKLRTQ FGKPICSFQA IQFKLAD ALI: 44-272 MHEVG LMTIGVPAEY GGAGLDHTAQ NIVAEEICWG DAGVGTVMVA STLLASDPVL VAANHEQKKE FYGRLLDGEL AAFCLTEPGA GSDAGGIATR CVKSGDEYIL NGSKQFISNG GTAGVYTVLA TLDKKMGTKG MCAFIVDRNT PGITVGKTED KLGIRTSNTT EVIFEDVRVP AKNLLGTEGQ GFYIIMKTLD LSRASIAAMA TGVSQACLDA SLEYSKLRTQ FGKP ENV: 30-367 WDNNHIYPE DCIKKMHEVG LMTIGVPAEY GGAGLDHTAQ NIVAEEICWG DAGVGTVMVA STLLASDPVL VAANHEQKKE FYGRLLDGEL AAFCLTEPGA GSDAGGIATR CVKSGDEYIL NGSKQFISNG GTAGVYTVLA TLDKKMGTKG MCAFIVDRNT PGITVGKTED KLGIRTSNTT EVIFEDVRVP AKNLLGTEGQ GFYIIMKTLD LSRASIAAMA TGVSQACLDA SLEYSKLRTQ FGKPICSFQA IQFKLADMAM RIEASRLLYL EASSLQDMNV PRFSKAASLA KAYAGDTAVF CATEAVQVFG GYGYTKDYPV EKYYRDAKIF QIYEGTGEV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MNFNYTEEQ LMLKESVRKF SENEIAPLVK WMETEKRTPW DLIKKIKDLG WCGIQYPEKY GGSGNTYVEY VIMQIEMARV YCSTACTISV NGMLGANIMK FATEEQKMKF LPEHLNGDGI GSFAFTEAST GSDPNALRTT CVRDGDEWVI NGEKVFITNA SLPGLMGIFC KDVEMGGKCT NILIPKGIKG YSIPRIYDKM GMHGLEVCDV LLDNVRVPYE NTTGGEAMRG KGFEVLLGST QIGKLSVCAQ AVGMAQAALE AAVKYSKERV QRGKPIAYFP TIQSLIGDMA TDVMVAHQAV LATAFKASEG KELASDAART RLFTSEAVHR VASKAMQVMG AYSYTTEFPI ERIFRDAKLT EIYEGVNEIQ RLIAAADLLR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-117 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 120-214 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF00441: 228-377 ◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MNFNYTEEQ LMLKESVRKF SENEIAPLVK WMETEKRTPW DLIKKIKDLG WCGIQYPEKY GGSGNTYVEY VIMQIEMARV YCSTACTISV NGMLGANIMK FATEEQKMKF LPEHLNGDGI GSFAFTEAST GSDPNALRTT CVRDGDEWVI NGEKVFITNA SLPGLMGIFC KDVEMGGKCT NILIPKGIKG YSIPRIYDKM GMHGLEVCDV LLDNVRVPYE NTTGGEAMRG KGFEVLLGST QIGKLSVCAQ AVGMAQAALE AAVKYSKERV QRGKPIAYFP TIQSLIGDMA TDVMVAHQAV LATAFKASEG KELASDAART RLFTSEAVHR VASKAMQVMG AYSYTTEFPI ERIFRDAKLT EIYEGVNEIQ RLIAAADLLR HMM: 52-283 IQYPEKY GGSGNTYVEY VIMQIEMARV YCSTACTISV NGMLGANIMK FATEEQKMKF LPEHLNGDGI GSFAFTEAST GSDPNALRTT CVRDGDEWVI NGEKVFITNA SLPGLMGIFC KDVEMGGKCT NILIPKGIKG YSIPRIYDKM GMHGLEVCDV LLDNVRVPYE NTTGGEAMRG KGFEVLLGST QIGKLSVCAQ AVGMAQAALE AAVKYSKERV QRGKPIAYFP TIQSL ALI: 45-271 KDLG WCGIQYPEKY GGSGNTYVEY VIMQIEMARV YCSTACTISV NGMLGANIMK FATEEQKMKF LPEHLNGDGI GSFAFTEAST GSDPNALRTT CVRDGDEWVI NGEKVFITNA SLPGLMGIFC KDVEMGGKCT NILIPKGIKG YSIPRIYDKM GMHGLEVCDV LLDNVRVPYE NTTGGEAMRG KGFEVLLGST QIGKLSVCAQ AVGMAQAALE AAVKYSKERV QRG ENV: 40-368 LIKKIKDLG WCGIQYPEKY GGSGNTYVEY VIMQIEMARV YCSTACTISV NGMLGANIMK FATEEQKMKF LPEHLNGDGI GSFAFTEAST GSDPNALRTT CVRDGDEWVI NGEKVFITNA SLPGLMGIFC KDVEMGGKCT NILIPKGIKG YSIPRIYDKM GMHGLEVCDV LLDNVRVPYE NTTGGEAMRG KGFEVLLGST QIGKLSVCAQ AVGMAQAALE AAVKYSKERV QRGKPIAYFP TIQSLIGDMA TDVMVAHQAV LATAFKASEG KELASDAART RLFTSEAVHR VASKAMQVMG AYSYTTEFPI ERIFRDAKLT EIYEGVNEIQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MELIKITID GKEVEVPAGT TIMKAADSVG INIPRLCYDP DLSALGACRL CVVEVEGNRL LPASCVTPIF PGMVVNTNSP AVVEARKTIL ELLVANHPLD CMTCDKLGDC KLADYCYQYG VKESPFVGEK HEYAIDDTNP FILRDLNKCI LCGACVRACE EMTGQDNLSY LNRGFHRKAT TAGDVDYIDS DCVFCGQCVA VCPTGALQEK TMVGQGRRWD IDRVRTTCPF CGTGCNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA LSSARCTNEE NYLVQKFTRA VMGNNNVDHC ART
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 2-78 ◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
PF10588: 84-123 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌
PF12838: 146-205 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF04879: 221-274 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF00384: 276-351 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MELIKITID GKEVEVPAGT TIMKAADSVG INIPRLCYDP DLSALGACRL CVVEVEGNRL LPASCVTPIF PGMVVNTNSP AVVEARKTIL ELLVANHPLD CMTCDKLGDC KLADYCYQYG VKESPFVGEK HEYAIDDTNP FILRDLNKCI LCGACVRACE EMTGQDNLSY LNRGFHRKAT TAGDVDYIDS DCVFCGQCVA VCPTGALQEK TMVGQGRRWD IDRVRTTCPF CGTGCNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA LSSARCTNEE NYLVQKFTRA VMGNNNVDHC ART HMM: 91-187 LVANHPLD CMTCDKLGDC KLADYCYQYG VKESPFVGEK HEYAIDDTNP FILRDLNKCI LCGACVRACE EMTGQDNLSY LNRGFHRKAT TAGDVDYID ALI: 233-318 CNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA ENV: 214-347 GRRWD IDRVRTTCPF CGTGCNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA LSSARCTNEE NYLVQKFTRA VMGNNNVDH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MELIKITID GKEVEVPAGT TIMKAADSVG INIPRLCYDP DLSALGACRL CVVEVEGNRL LPASCVTPIF PGMVVNTNSP AVVEARKTIL ELLVANHPLD CMTCDKLGDC KLADYCYQYG VKESPFVGEK HEYAIDDTNP FILRDLNKCI LCGACVRACE EMTGQDNLSY LNRGFHRKAT TAGDVDYIDS DCVFCGQCVA VCPTGALQEK TMVGQGRRWD IDRVRTTCPF CGTGCNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA LSSARCTNEE NYLVQKFTRA VMGNNNVDHC ART HMM: 103-170 DKLGDC KLADYCYQYG VKESPFVGEK HEYAIDDTNP FILRDLNKCI LCGACVRACE EMTGQDNLSY LN ALI: 253-317 STVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFA ENV: 208-347 K TMVGQGRRWD IDRVRTTCPF CGTGCNFDLA VKNGKVIGVL SNPDSTVNQR SLCVKGRFGW DFIYNEKRLT TPLIKKNGKF EEASWDEAFD LIAQRFGEIK AQYGSESFAA LSSARCTNEE NYLVQKFTRA VMGNNNVDH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MAYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
PF01977: 9-423 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MAYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE HMM: 2-413 YKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDP ALI: 3-426 KDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDV ENV: 2-459 YKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP K Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MAYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE HMM: 1-478 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY ALI: 1-479 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY G ENV: 1-481 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MAYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE HMM: 1-403 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEV ALI: 1-418 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM ENV: 1-481 AYKDLQEF IQVLESEGEL KRISVEVDPE LEITEITDRV SKNYGPALLF EKVKGSDMPV LINAFGSEKR MALSLQVDKL DDLATEIMGL LEIADSVPQS LLDKVKVLPK LAQLSSFLPR MVKSGACQEV VDLNPSLDKI PVLKCWPEDA GRFITLPQVY TKDPESGKRN VGMYRLQVFD GQSTGMHWHT HHDGAENYRK NCQRGQATEV AVALGGDPAI TYAGTAPLPK DIDELIFAGF IRKKPVELVK CKTVNLEVPA DAEIVIEGYV DPYERRIEGP FGDHTGYYSL ADEYPVFHVK CITHKKNAVY PTTIVGKPPQ EDCYMALATE RIFLPLLKLQ LPEVVDMHLP MEGVFHNCVL VAIKKSFPGH ARKIMSSLWG MGQMMFAKFI IVVDEDVNVQ NVSEVMWKVF NNVDPRRDTM IVEGPLDVLD HSAPLPLIGS KMGIDATKKW MSEGHSREWP KDIVMSPEIK EMVSRRWSEY GFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MVDLVKLII NGKEVEAPAG STILQAAELA GIEIPRLCYD KDLSPLGACR LCVVEVKGNR LLPASCVTPV FQGMEVETES PAVVEARKTI LELLIANHPL DCLTCEKAGA CKLQDYCYRY GIKGSPFVGQ KHAYAIDDSN PFIVRDLNKC ILCGACVRAC EELTGADNLS YLKRGFHRKA TTAGDVDYID SDCVFCGQCV AVCPTGALTE KTMVGQGRRW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA ALSSARCTNE ENFLVSKFSR AVMGTNNVDH CART
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 4-79 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
PF10588: 85-124 ◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌
PF12838: 147-206 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF04879: 221-275 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00384: 277-352 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MVDLVKLII NGKEVEAPAG STILQAAELA GIEIPRLCYD KDLSPLGACR LCVVEVKGNR LLPASCVTPV FQGMEVETES PAVVEARKTI LELLIANHPL DCLTCEKAGA CKLQDYCYRY GIKGSPFVGQ KHAYAIDDSN PFIVRDLNKC ILCGACVRAC EELTGADNLS YLKRGFHRKA TTAGDVDYID SDCVFCGQCV AVCPTGALTE KTMVGQGRRW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA ALSSARCTNE ENFLVSKFSR AVMGTNNVDH CART HMM: 115-187 CYRY GIKGSPFVGQ KHAYAIDDSN PFIVRDLNKC ILCGACVRAC EELTGADNLS YLKRGFHRKA TTAGDVDYI ALI: 251-319 NPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA A ENV: 217-330 RW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA ALSSARCTNE EN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MVDLVKLII NGKEVEAPAG STILQAAELA GIEIPRLCYD KDLSPLGACR LCVVEVKGNR LLPASCVTPV FQGMEVETES PAVVEARKTI LELLIANHPL DCLTCEKAGA CKLQDYCYRY GIKGSPFVGQ KHAYAIDDSN PFIVRDLNKC ILCGACVRAC EELTGADNLS YLKRGFHRKA TTAGDVDYID SDCVFCGQCV AVCPTGALTE KTMVGQGRRW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA ALSSARCTNE ENFLVSKFSR AVMGTNNVDH CART HMM: 57-171 NR LLPASCVTPV FQGMEVETES PAVVEARKTI LELLIANHPL DCLTCEKAGA CKLQDYCYRY GIKGSPFVGQ KHAYAIDDSN PFIVRDLNKC ILCGACVRAC EELTGADNLS YLK ALI: 217-319 RW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA A ENV: 206-349 LTE KTMVGQGRRW DIERVRTTCP FCGTGCNFDL AVKDGKVIGV LSNPDAPVNQ RSLCVKGRFG WDFIYNENRL TTPLIKKNGE FEPASWDEAF SLIATRFKEI KEKYGPDSFA ALSSARCTNE ENFLVSKFSR AVMGTNNVDH C Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MIKLTIDGK EIEVARGTML LDACRQAGAD IPTLCYDPDL RLAGSCRMCV VDVKGRPALV ASCVAPAENG MVVQTESDDV VESRKIILEL LAARHKFECP TCEKDGDCKL QDYMYRYGVK ESRYDGEGPH FGMEDPNPFI ERDYDKCIMC TRCVRACDGI TGAQAINVKD RGHHAKIAAP FDGKLADSTC VFCGQCIMVC PVGALTSKVA AGKGKPAQNE KVLTTCTYCG TGCTLELNVN NDRVVGVTSN RDADWSPVNK GALCVKGRFG WDFIHSPDRL TTPMIRENGE LRPASWDEAL DFAAGKIKGI KEKYGSDSLA MFSSARVTNE ENYIAQKLMR AVIGTNNVDH CARL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 0-76 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
PF10588: 82-122 ◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
PF14697: 141-203 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF04879: 219-274 ♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF00384: 277-353 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MIKLTIDGK EIEVARGTML LDACRQAGAD IPTLCYDPDL RLAGSCRMCV VDVKGRPALV ASCVAPAENG MVVQTESDDV VESRKIILEL LAARHKFECP TCEKDGDCKL QDYMYRYGVK ESRYDGEGPH FGMEDPNPFI ERDYDKCIMC TRCVRACDGI TGAQAINVKD RGHHAKIAAP FDGKLADSTC VFCGQCIMVC PVGALTSKVA AGKGKPAQNE KVLTTCTYCG TGCTLELNVN NDRVVGVTSN RDADWSPVNK GALCVKGRFG WDFIHSPDRL TTPMIRENGE LRPASWDEAL DFAAGKIKGI KEKYGSDSLA MFSSARVTNE ENYIAQKLMR AVIGTNNVDH CARL HMM: 110-177 DYMYRYGVK ESRYDGEGPH FGMEDPNPFI ERDYDKCIMC TRCVRACDGI TGAQAINVKD RGHHAKIAA ALI: 262-325 CVKGRFG WDFIHSPDRL TTPMIRENGE LRPASWDEAL DFAAGKIKGI KEKYGSDSLA MFSSARV ENV: 244-352 GVTSN RDADWSPVNK GALCVKGRFG WDFIHSPDRL TTPMIRENGE LRPASWDEAL DFAAGKIKGI KEKYGSDSLA MFSSARVTNE ENYIAQKLMR AVIGTNNVDH CARL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MEWVNVIIA ALFFLAILYI ILQVLFKPVK LLWKLAINSL MGLVLLLISN YIGAYFQFDL PVNIITVLIA GFLGLPGIIL LICFQLLVR
10 20 30 40 50 60 70 80
PF07441: 13-85 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
Sequence: MEWVNVIIA ALFFLAILYI ILQVLFKPVK LLWKLAINSL MGLVLLLISN YIGAYFQFDL PVNIITVLIA GFLGLPGIIL LICFQLLVR HMM: 225-276 ALI: 2-54 WVNVIIA ALFFLAILYI ILQVLFKPVK LLWKLAINSL MGLVLLLISN YIGAYF ENV: 1-54 EWVNVIIA ALFFLAILYI ILQVLFKPVK LLWKLAINSL MGLVLLLISN YIGAYF Position: 10 20 30 40 50 60 70 80
Sequence: MKTFPELFS PAYIGKLLVK NRIVMAPMLV SYASSDGEVS ERLLDYYEAR ARGGAGLIVV EAACVDAPTG RESFRQINID SLRYVAGLQQ LAQHIKAYGC RTFIQLFHAG RQTSSLFTGV QPVAPSPLAC PMVKEIPREL TGEEIKEIEN KFSQAAAYAF MAGFDGVELH AAHGYLINQF LSPHSNLRQD EYGGSLENRM RFLLNIIKKI KTSSPGLIIS VRINMDDFVP GGLELKESVE ICQHLEQAGV ELINCSSGTY ESGLKSIEPA SYKEGWRVYL AGELKKWIHI PVIAGGMLNN PAFANQLIAG GQADFIFLGR SLLADSEWPH KVRESGTEDI RPCIRCNNCI DNNFRGMMVD CSVNPLTGRE RHFSQEGKKL LHKANVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACLPPH KHRVAYLRDY LIRQVEKSGV EAFLNCSFNL ESLPDLNPDY LLIATGSKPL LPQIPGWDQS YCLGIREVLE RKPEIKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQNK YLAADMEKKN RRDLMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFTPNNALYI EAQNRHKNVY LIGDAFQVKG FKNAFLQGEA VAHMIATGLK K
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
PF00724: 5-333 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF07992: 383-609 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
Sequence: MKTFPELFS PAYIGKLLVK NRIVMAPMLV SYASSDGEVS ERLLDYYEAR ARGGAGLIVV EAACVDAPTG RESFRQINID SLRYVAGLQQ LAQHIKAYGC RTFIQLFHAG RQTSSLFTGV QPVAPSPLAC PMVKEIPREL TGEEIKEIEN KFSQAAAYAF MAGFDGVELH AAHGYLINQF LSPHSNLRQD EYGGSLENRM RFLLNIIKKI KTSSPGLIIS VRINMDDFVP GGLELKESVE ICQHLEQAGV ELINCSSGTY ESGLKSIEPA SYKEGWRVYL AGELKKWIHI PVIAGGMLNN PAFANQLIAG GQADFIFLGR SLLADSEWPH KVRESGTEDI RPCIRCNNCI DNNFRGMMVD CSVNPLTGRE RHFSQEGKKL LHKANVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACLPPH KHRVAYLRDY LIRQVEKSGV EAFLNCSFNL ESLPDLNPDY LLIATGSKPL LPQIPGWDQS YCLGIREVLE RKPEIKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQNK YLAADMEKKN RRDLMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFTPNNALYI EAQNRHKNVY LIGDAFQVKG FKNAFLQGEA VAHMIATGLK K HMM: 5-49 ELFS PAYIGKLLVK NRIVMAPMLV SYASSDGEVS ERLLDYYEAR A ALI: 383-425 NVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACL ENV: 380-431 HKANVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACLPPH KHR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MKTFPELFS PAYIGKLLVK NRIVMAPMLV SYASSDGEVS ERLLDYYEAR ARGGAGLIVV EAACVDAPTG RESFRQINID SLRYVAGLQQ LAQHIKAYGC RTFIQLFHAG RQTSSLFTGV QPVAPSPLAC PMVKEIPREL TGEEIKEIEN KFSQAAAYAF MAGFDGVELH AAHGYLINQF LSPHSNLRQD EYGGSLENRM RFLLNIIKKI KTSSPGLIIS VRINMDDFVP GGLELKESVE ICQHLEQAGV ELINCSSGTY ESGLKSIEPA SYKEGWRVYL AGELKKWIHI PVIAGGMLNN PAFANQLIAG GQADFIFLGR SLLADSEWPH KVRESGTEDI RPCIRCNNCI DNNFRGMMVD CSVNPLTGRE RHFSQEGKKL LHKANVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACLPPH KHRVAYLRDY LIRQVEKSGV EAFLNCSFNL ESLPDLNPDY LLIATGSKPL LPQIPGWDQS YCLGIREVLE RKPEIKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQNK YLAADMEKKN RRDLMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFTPNNALYI EAQNRHKNVY LIGDAFQVKG FKNAFLQGEA VAHMIATGLK K HMM: 173-207 YLINQF LSPHSNLRQD EYGGSLENRM RFLLNIIKK ALI: 503-536 IKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQ ENV: 497-546 LE RKPEIKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQNK YLAADMEK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MKTFPELFS PAYIGKLLVK NRIVMAPMLV SYASSDGEVS ERLLDYYEAR ARGGAGLIVV EAACVDAPTG RESFRQINID SLRYVAGLQQ LAQHIKAYGC RTFIQLFHAG RQTSSLFTGV QPVAPSPLAC PMVKEIPREL TGEEIKEIEN KFSQAAAYAF MAGFDGVELH AAHGYLINQF LSPHSNLRQD EYGGSLENRM RFLLNIIKKI KTSSPGLIIS VRINMDDFVP GGLELKESVE ICQHLEQAGV ELINCSSGTY ESGLKSIEPA SYKEGWRVYL AGELKKWIHI PVIAGGMLNN PAFANQLIAG GQADFIFLGR SLLADSEWPH KVRESGTEDI RPCIRCNNCI DNNFRGMMVD CSVNPLTGRE RHFSQEGKKL LHKANVMVVG GGPAGMQAAL SLKSRGLNVT LYEKEKSLGG LLNLACLPPH KHRVAYLRDY LIRQVEKSGV EAFLNCSFNL ESLPDLNPDY LLIATGSKPL LPQIPGWDQS YCLGIREVLE RKPEIKGKRV VIIGGGSNGC EVADFLLAGN NQITIVEQNK YLAADMEKKN RRDLMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFTPNNALYI EAQNRHKNVY LIGDAFQVKG FKNAFLQGEA VAHMIATGLK K HMM: 300-344 AFANQLIAG GQADFIFLGR SLLADSEWPH KVRESGTEDI RPCIRC ALI: 552-601 LMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFT ENV: 548-614 N RRDLMNRLEE GKVNKKTSSQ VMEIKDQQLQ LKSQQGAYEC LEADYIVLAT GFTPNNALYI EAQNRH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MNKVDVAII GAGVVGLAIA WKIASKTGKT VVVIERNNKY GQEISSRNSE VIHSGLYYSP SMLKTQLCVR GNSLLYEFCE QRNVAHYRRG KILVALNQGE EEQLDALYNN ALSNTVSVNR LTGRKVLEME PEVLAYSGLY FPNTGTVDVH ELMQALFFEG RQAGVVYLFY SIVKEAVYTG SGYEIGTQRE TIHAQNVINC AGLGAETIAQ LIGIDTIKSG YHLHPCKGDY FKIKRKLKIQ HLVYSVPTSN SLGIHLSMDR EGYLRLGPNA YYVEDLNYSV NESHGTEFFQ AARQYIPSLK MEDLMPDFAG IRPKIQGPGE EMKDFVIKDE SDPGYPGWIN LIGIESPGLT SCLAIGDYVK ELI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
PF01266: 4-361 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MNKVDVAII GAGVVGLAIA WKIASKTGKT VVVIERNNKY GQEISSRNSE VIHSGLYYSP SMLKTQLCVR GNSLLYEFCE QRNVAHYRRG KILVALNQGE EEQLDALYNN ALSNTVSVNR LTGRKVLEME PEVLAYSGLY FPNTGTVDVH ELMQALFFEG RQAGVVYLFY SIVKEAVYTG SGYEIGTQRE TIHAQNVINC AGLGAETIAQ LIGIDTIKSG YHLHPCKGDY FKIKRKLKIQ HLVYSVPTSN SLGIHLSMDR EGYLRLGPNA YYVEDLNYSV NESHGTEFFQ AARQYIPSLK MEDLMPDFAG IRPKIQGPGE EMKDFVIKDE SDPGYPGWIN LIGIESPGLT SCLAIGDYVK ELI HMM: 4-42 DVAII GAGVVGLAIA WKIASKTGKT VVVIERNNKY GQEI ALI: 3-40 VDVAII GAGVVGLAIA WKIASKTGKT VVVIERNNKY GQ ENV: 1-51 NKVDVAII GAGVVGLAIA WKIASKTGKT VVVIERNNKY GQEISSRNSE VIH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360
Sequence: MQDLYWECK VCEACGVCGK SEEECRLYDE YYGFGKSPGA GKAERGSLAV LERDARKLNQ ANQGIINRLN GRIVKVIEGE STALLTIAMG EHYISSMMPL SRFRESGKKI GDLLAVAFKS IDVKVMN
10 20 30 40 50 60 70 80 90 100 110 120
Sequence: MQDLYWECK VCEACGVCGK SEEECRLYDE YYGFGKSPGA GKAERGSLAV LERDARKLNQ ANQGIINRLN GRIVKVIEGE STALLTIAMG EHYISSMMPL SRFRESGKKI GDLLAVAFKS IDVKVMN HMM: 705-752 ALI: 25-73 LYDE YYGFGKSPGA GKAERGSLAV LERDARKLNQ ANQGIINRLN GRIVK ENV: 11-96 EACGVCGK SEEECRLYDE YYGFGKSPGA GKAERGSLAV LERDARKLNQ ANQGIINRLN GRIVKVIEGE STALLTIAMG EHYISSMM Position: 10 20 30 40 50 60 70 80 90 100 110 120
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INALRGENNV QGATDMALLF HIIPGYVDSP MNTADNKDLI SFIRKVTPGA AKLPFTNLAE FRELVKAGFP NSGWKIHTSK WVVSMLKAWY GKAATPGNDF AYHYLPKRDE KKNYSHIAMF EAMHRGEIEG LFVNGSNPVV GGPNSNKEQE ALTKLKWMVS IDLWANETAE FWTHQAWDRP VKNPDVPRMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKRKEDE PIVNMTWDYD DEHGHDDIMK VALELCGYNV ADGKPVEGFA KLADDGSTAC GCWVYCGAMT FKDGKNIYKP QLRKKDDPSG LGIHPEWGWA WPMNRRIVYN RCSVQPDGVT PWPGDAKRQL VKWDPLALAD PKNPTSLGSW VGVDVPDFIK TTGPDKAAFT SPFIMRPEGK GCLFAAKNSL KDGPFPEHYE PWESPTVNIM NKQNLNPAVK VWEPDKQGTR DKYPIIGTTY RVVEHWQTGA LTRNLPWLAE LMPDMMVELS EELAKEKGIK NGHNVVISTS RGDVKAVACV TKRFKPFNIN GQYIHQIGLL WQFGFKGYAT GDPANRLTPH IGDANAMCPE YKAWLCDIRR A
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
PF00384: 1-399 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
PF01568: 716-833 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INALRGENNV QGATDMALLF HIIPGYVDSP MNTADNKDLI SFIRKVTPGA AKLPFTNLAE FRELVKAGFP NSGWKIHTSK WVVSMLKAWY GKAATPGNDF AYHYLPKRDE KKNYSHIAMF EAMHRGEIEG LFVNGSNPVV GGPNSNKEQE ALTKLKWMVS IDLWANETAE FWTHQAWDRP VKNPDVPRMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKRKEDE PIVNMTWDYD DEHGHDDIMK VALELCGYNV ADGKPVEGFA KLADDGSTAC GCWVYCGAMT FKDGKNIYKP QLRKKDDPSG LGIHPEWGWA WPMNRRIVYN RCSVQPDGVT PWPGDAKRQL VKWDPLALAD PKNPTSLGSW VGVDVPDFIK TTGPDKAAFT SPFIMRPEGK GCLFAAKNSL KDGPFPEHYE PWESPTVNIM NKQNLNPAVK VWEPDKQGTR DKYPIIGTTY RVVEHWQTGA LTRNLPWLAE LMPDMMVELS EELAKEKGIK NGHNVVISTS RGDVKAVACV TKRFKPFNIN GQYIHQIGLL WQFGFKGYAT GDPANRLTPH IGDANAMCPE YKAWLCDIRR A HMM: 247-467 LF HIIPGYVDSP MNTADNKDLI SFIRKVTPGA AKLPFTNLAE FRELVKAGFP NSGWKIHTSK WVVSMLKAWY GKAATPGNDF AYHYLPKRDE KKNYSHIAMF EAMHRGEIEG LFVNGSNPVV GGPNSNKEQE ALTKLKWMVS IDLWANETAE FWTHQAWDRP VKNPDVPRMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWI ALI: 27-232 SM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INAL ENV: 3-250 HIVDLK NTDCALIMGS NAAENHPISM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INALRGENNV QGATDMALLF HI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INALRGENNV QGATDMALLF HIIPGYVDSP MNTADNKDLI SFIRKVTPGA AKLPFTNLAE FRELVKAGFP NSGWKIHTSK WVVSMLKAWY GKAATPGNDF AYHYLPKRDE KKNYSHIAMF EAMHRGEIEG LFVNGSNPVV GGPNSNKEQE ALTKLKWMVS IDLWANETAE FWTHQAWDRP VKNPDVPRMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKRKEDE PIVNMTWDYD DEHGHDDIMK VALELCGYNV ADGKPVEGFA KLADDGSTAC GCWVYCGAMT FKDGKNIYKP QLRKKDDPSG LGIHPEWGWA WPMNRRIVYN RCSVQPDGVT PWPGDAKRQL VKWDPLALAD PKNPTSLGSW VGVDVPDFIK TTGPDKAAFT SPFIMRPEGK GCLFAAKNSL KDGPFPEHYE PWESPTVNIM NKQNLNPAVK VWEPDKQGTR DKYPIIGTTY RVVEHWQTGA LTRNLPWLAE LMPDMMVELS EELAKEKGIK NGHNVVISTS RGDVKAVACV TKRFKPFNIN GQYIHQIGLL WQFGFKGYAT GDPANRLTPH IGDANAMCPE YKAWLCDIRR A HMM: 634-706 PDFIK TTGPDKAAFT SPFIMRPEGK GCLFAAKNSL KDGPFPEHYE PWESPTVNIM NKQNLNPAVK VWEPDKQG ALI: 428-498 F LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKRKEDE PIVNMTWDYD ENV: 414-522 VPRMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKRKEDE PIVNMTWDYD DEHGHDDIMK VALELCGYNV ADGK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INALRGENNV QGATDMALLF HIIPGYVDSP MNTADNKDLI SFIRKVTPGA AKLPFTNLAE FRELVKAGFP NSGWKIHTSK WVVSMLKAWY GKAATPGNDF AYHYLPKRDE KKNYSHIAMF EAMHRGEIEG LFVNGSNPVV GGPNSNKEQE ALTKLKWMVS IDLWANETAE FWTHQAWDRP VKNPDVPRMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKRKEDE PIVNMTWDYD DEHGHDDIMK VALELCGYNV ADGKPVEGFA KLADDGSTAC GCWVYCGAMT FKDGKNIYKP QLRKKDDPSG LGIHPEWGWA WPMNRRIVYN RCSVQPDGVT PWPGDAKRQL VKWDPLALAD PKNPTSLGSW VGVDVPDFIK TTGPDKAAFT SPFIMRPEGK GCLFAAKNSL KDGPFPEHYE PWESPTVNIM NKQNLNPAVK VWEPDKQGTR DKYPIIGTTY RVVEHWQTGA LTRNLPWLAE LMPDMMVELS EELAKEKGIK NGHNVVISTS RGDVKAVACV TKRFKPFNIN GQYIHQIGLL WQFGFKGYAT GDPANRLTPH IGDANAMCPE YKAWLCDIRR A HMM: 243-464 DMALLF HIIPGYVDSP MNTADNKDLI SFIRKVTPGA AKLPFTNLAE FRELVKAGFP NSGWKIHTSK WVVSMLKAWY GKAATPGNDF AYHYLPKRDE KKNYSHIAMF EAMHRGEIEG LFVNGSNPVV GGPNSNKEQE ALTKLKWMVS IDLWANETAE FWTHQAWDRP VKNPDVPRMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSD ALI: 27-232 SM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INAL ENV: 6-247 DLK NTDCALIMGS NAAENHPISM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INALRGENNV QGATDMALL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INALRGENNV QGATDMALLF HIIPGYVDSP MNTADNKDLI SFIRKVTPGA AKLPFTNLAE FRELVKAGFP NSGWKIHTSK WVVSMLKAWY GKAATPGNDF AYHYLPKRDE KKNYSHIAMF EAMHRGEIEG LFVNGSNPVV GGPNSNKEQE ALTKLKWMVS IDLWANETAE FWTHQAWDRP VKNPDVPRMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKRKEDE PIVNMTWDYD DEHGHDDIMK VALELCGYNV ADGKPVEGFA KLADDGSTAC GCWVYCGAMT FKDGKNIYKP QLRKKDDPSG LGIHPEWGWA WPMNRRIVYN RCSVQPDGVT PWPGDAKRQL VKWDPLALAD PKNPTSLGSW VGVDVPDFIK TTGPDKAAFT SPFIMRPEGK GCLFAAKNSL KDGPFPEHYE PWESPTVNIM NKQNLNPAVK VWEPDKQGTR DKYPIIGTTY RVVEHWQTGA LTRNLPWLAE LMPDMMVELS EELAKEKGIK NGHNVVISTS RGDVKAVACV TKRFKPFNIN GQYIHQIGLL WQFGFKGYAT GDPANRLTPH IGDANAMCPE YKAWLCDIRR A HMM: 653-684 MRPEGK GCLFAAKNSL KDGPFPEHYE PWESPT ALI: 448-479 V QYRWKGAEPV GDSKSDLWIY NELVKKIKQK Y ENV: 427-484 FF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INALRGENNV QGATDMALLF HIIPGYVDSP MNTADNKDLI SFIRKVTPGA AKLPFTNLAE FRELVKAGFP NSGWKIHTSK WVVSMLKAWY GKAATPGNDF AYHYLPKRDE KKNYSHIAMF EAMHRGEIEG LFVNGSNPVV GGPNSNKEQE ALTKLKWMVS IDLWANETAE FWTHQAWDRP VKNPDVPRMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKRKEDE PIVNMTWDYD DEHGHDDIMK VALELCGYNV ADGKPVEGFA KLADDGSTAC GCWVYCGAMT FKDGKNIYKP QLRKKDDPSG LGIHPEWGWA WPMNRRIVYN RCSVQPDGVT PWPGDAKRQL VKWDPLALAD PKNPTSLGSW VGVDVPDFIK TTGPDKAAFT SPFIMRPEGK GCLFAAKNSL KDGPFPEHYE PWESPTVNIM NKQNLNPAVK VWEPDKQGTR DKYPIIGTTY RVVEHWQTGA LTRNLPWLAE LMPDMMVELS EELAKEKGIK NGHNVVISTS RGDVKAVACV TKRFKPFNIN GQYIHQIGLL WQFGFKGYAT GDPANRLTPH IGDANAMCPE YKAWLCDIRR A HMM: 248-482 F HIIPGYVDSP MNTADNKDLI SFIRKVTPGA AKLPFTNLAE FRELVKAGFP NSGWKIHTSK WVVSMLKAWY GKAATPGNDF AYHYLPKRDE KKNYSHIAMF EAMHRGEIEG LFVNGSNPVV GGPNSNKEQE ALTKLKWMVS IDLWANETAE FWTHQAWDRP VKNPDVPRMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGAS ALI: 12-233 CALIMGS NAAENHPISM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INALR ENV: 5-248 VDLK NTDCALIMGS NAAENHPISM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INALRGENNV QGATDMALLF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MTNHIVDLK NTDCALIMGS NAAENHPISM RWLLKARDTR GAKIIHVDPR YTRTSARADL YTPLRSGTDI AFLGGMIKYI IDNELYHRDY VVNYTNASYL IKDEFDFHDG LFSGWDKENK KYDVSSWDYQ ADANGLPLTD PSLQNPRCVF QLMKKHYERY DIDTVCKITG TPKNKYLEVL KTFCATGAPD KTGTILYAMG ITQHTVGAQN IRAFAIVQLL LGNMGRPGGG INALRGENNV QGATDMALLF HIIPGYVDSP MNTADNKDLI SFIRKVTPGA AKLPFTNLAE FRELVKAGFP NSGWKIHTSK WVVSMLKAWY GKAATPGNDF AYHYLPKRDE KKNYSHIAMF EAMHRGEIEG LFVNGSNPVV GGPNSNKEQE ALTKLKWMVS IDLWANETAE FWTHQAWDRP VKNPDVPRMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKRKEDE PIVNMTWDYD DEHGHDDIMK VALELCGYNV ADGKPVEGFA KLADDGSTAC GCWVYCGAMT FKDGKNIYKP QLRKKDDPSG LGIHPEWGWA WPMNRRIVYN RCSVQPDGVT PWPGDAKRQL VKWDPLALAD PKNPTSLGSW VGVDVPDFIK TTGPDKAAFT SPFIMRPEGK GCLFAAKNSL KDGPFPEHYE PWESPTVNIM NKQNLNPAVK VWEPDKQGTR DKYPIIGTTY RVVEHWQTGA LTRNLPWLAE LMPDMMVELS EELAKEKGIK NGHNVVISTS RGDVKAVACV TKRFKPFNIN GQYIHQIGLL WQFGFKGYAT GDPANRLTPH IGDANAMCPE YKAWLCDIRR A HMM: 649-707 SPFIMRPEGK GCLFAAKNSL KDGPFPEHYE PWESPTVNIM NKQNLNPAVK VWEPDKQGT ALI: 428-484 F LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKR ENV: 416-508 RMT PAEIGTEVFF LPAAAVYEKE GTAAQTGRWV QYRWKGAEPV GDSKSDLWIY NELVKKIKQK YGASKRKEDE PIVNMTWDYD DEHGHDDIMK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840
Sequence: MMLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EIWAEMASLT PSMKGINYGR LENESLQWPC PSTDHPGTPF LHAGKFTRGL GLFQPSEHIP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATPTNALTSH HLDPITGTGE YKVAAVKIEK I
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
PF00384: 1-302 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF01568: 399-503 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MMLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EIWAEMASLT PSMKGINYGR LENESLQWPC PSTDHPGTPF LHAGKFTRGL GLFQPSEHIP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATPTNALTSH HLDPITGTGE YKVAAVKIEK I HMM: 254-314 FLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQM ALI: 22-82 AARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTEN ENV: 13-83 PIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MMLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EIWAEMASLT PSMKGINYGR LENESLQWPC PSTDHPGTPF LHAGKFTRGL GLFQPSEHIP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATPTNALTSH HLDPITGTGE YKVAAVKIEK I HMM: 387-472 IP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIW ALI: 84-171 EELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQG ENV: 81-200 ENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MMLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EIWAEMASLT PSMKGINYGR LENESLQWPC PSTDHPGTPF LHAGKFTRGL GLFQPSEHIP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATPTNALTSH HLDPITGTGE YKVAAVKIEK I HMM: 612-683 ALI: 250-318 SNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM ENV: 241-329 DTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR E Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MMLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EIWAEMASLT PSMKGINYGR LENESLQWPC PSTDHPGTPF LHAGKFTRGL GLFQPSEHIP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATPTNALTSH HLDPITGTGE YKVAAVKIEK I HMM: 874-915 ALI: 432-473 NPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWM ENV: 417-481 SK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MMLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EIWAEMASLT PSMKGINYGR LENESLQWPC PSTDHPGTPF LHAGKFTRGL GLFQPSEHIP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATPTNALTSH HLDPITGTGE YKVAAVKIEK I HMM: 251-311 NLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETI ALI: 22-82 AARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTEN ENV: 3-85 LIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MMLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EIWAEMASLT PSMKGINYGR LENESLQWPC PSTDHPGTPF LHAGKFTRGL GLFQPSEHIP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATPTNALTSH HLDPITGTGE YKVAAVKIEK I HMM: 388-464 P PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTD ALI: 87-163 KE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPM ENV: 82-237 NYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MMLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EIWAEMASLT PSMKGINYGR LENESLQWPC PSTDHPGTPF LHAGKFTRGL GLFQPSEHIP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATPTNALTSH HLDPITGTGE YKVAAVKIEK I HMM: 610-642 ALI: 251-283 NLDFLVVQ ELFLTETAEY ADVVLPAASF AECNG ENV: 208-319 K VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MMLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EIWAEMASLT PSMKGINYGR LENESLQWPC PSTDHPGTPF LHAGKFTRGL GLFQPSEHIP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATPTNALTSH HLDPITGTGE YKVAAVKIEK I HMM: 255-330 LVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EI ALI: 7-82 NA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTEN ENV: 1-84 MLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MMLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EIWAEMASLT PSMKGINYGR LENESLQWPC PSTDHPGTPF LHAGKFTRGL GLFQPSEHIP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATPTNALTSH HLDPITGTGE YKVAAVKIEK I HMM: 403-480 TGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT AT ALI: 85-162 ELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCP ENV: 82-176 NYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MMLLIGTNA TEAHPIIGYK MRQAARRGAK MVVCDPRHID LVDEADYWLR QKPGTDIPLL NGLMHIIIKE GLEDKKFIAE RTENYEELKE IVASYTPERV AELTGVSADD LYAVARLYAT TDKAMIFYTL GITEHICGTR NVMSIANLAM LTGHLGRPGT GVCPMRGQNN VQGACDMGAL PNVYPGYQSV TVEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYESPR EIWAEMASLT PSMKGINYGR LENESLQWPC PSTDHPGTPF LHAGKFTRGL GLFQPSEHIP PGEMPDEEYP FLLSTGRILY HYNVTTPYSK GISSIWDKEM AEVNPLDAEK LGLVTGSQVK VSSRRGEAIT AVKVTDRVLP GVIWMSFHYT ATPTNALTSH HLDPITGTGE YKVAAVKIEK I HMM: 601-700 ALI: 226-320 KSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GY ENV: 190-325 VEANQEKFE KAWGGKIPAK VGLKIPEMFE AAHEGKVKSM YILGENPVLT DPDTNHIRAA LSNLDFLVVQ ELFLTETAEY ADVVLPAASF AECNGTFTNT ERRVQRVRKA IEPIPGQANW ETICQMVTRM GYPMNYE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510
Sequence: MRVTRRQFL KVTGATAASL AVVDLGFDMT ATASAIKGVR TRNVTPTPTV CPYCASGCGL MVYSERDAAG RFVKLLSVQG DPDNPINQGG ACSKGAAMFN LREIYEEGTG KQVINPKRVQ KPMYRAPGSD KWEEKDWDWM LDKIADRIKE TRDSSFIHKE KIADGSEIIV NRTEKIASLG GSGLDNEEAY VLSKMMRSLG VVYLETQARI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
PF04879: 45-99 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MRVTRRQFL KVTGATAASL AVVDLGFDMT ATASAIKGVR TRNVTPTPTV CPYCASGCGL MVYSERDAAG RFVKLLSVQG DPDNPINQGG ACSKGAAMFN LREIYEEGTG KQVINPKRVQ KPMYRAPGSD KWEEKDWDWM LDKIADRIKE TRDSSFIHKE KIADGSEIIV NRTEKIASLG GSGLDNEEAY VLSKMMRSLG VVYLETQARI HMM: 4-35 RRQFL KVTGATAASL AVVDLGFDMT ATASAIK ALI: 1-32 RVTRRQFL KVTGATAASL AVVDLGFDMT ATAS ENV: 1-45 RVTRRQFL KVTGATAASL AVVDLGFDMT ATASAIKGVR TRNVTPT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MRVTRRQFL KVTGATAASL AVVDLGFDMT ATASAIKGVR TRNVTPTPTV CPYCASGCGL MVYSERDAAG RFVKLLSVQG DPDNPINQGG ACSKGAAMFN LREIYEEGTG KQVINPKRVQ KPMYRAPGSD KWEEKDWDWM LDKIADRIKE TRDSSFIHKE KIADGSEIIV NRTEKIASLG GSGLDNEEAY VLSKMMRSLG VVYLETQARI HMM: 118-201 Q KPMYRAPGSD KWEEKDWDWM LDKIADRIKE TRDSSFIHKE KIADGSEIIV NRTEKIASLG GSGLDNEEAY VLSKMMRSLG VVY ALI: 109-185 KQVINPKRVQ KPMYRAPGSD KWEEKDWDWM LDKIADRIKE TRDSSFIHKE KIADGSEIIV NRTEKIASLG GSGLDNE ENV: 36-194 GVR TRNVTPTPTV CPYCASGCGL MVYSERDAAG RFVKLLSVQG DPDNPINQGG ACSKGAAMFN LREIYEEGTG KQVINPKRVQ KPMYRAPGSD KWEEKDWDWM LDKIADRIKE TRDSSFIHKE KIADGSEIIV NRTEKIASLG GSGLDNEEAY VLSKMM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MRVTRRQFL KVTGATAASL AVVDLGFDMT ATASAIKGVR TRNVTPTPTV CPYCASGCGL MVYSERDAAG RFVKLLSVQG DPDNPINQGG ACSKGAAMFN LREIYEEGTG KQVINPKRVQ KPMYRAPGSD KWEEKDWDWM LDKIADRIKE TRDSSFIHKE KIADGSEIIV NRTEKIASLG GSGLDNEEAY VLSKMMRSLG VVYLETQARI HMM: 19-45 AVVDLGFDMT ATASAIKGVR TRNVTPT ALI: 2-28 VTRRQFL KVTGATAASL AVVDLGFDMT ENV: 1-50 RVTRRQFL KVTGATAASL AVVDLGFDMT ATASAIKGVR TRNVTPTPTV CP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MRVTRRQFL KVTGATAASL AVVDLGFDMT ATASAIKGVR TRNVTPTPTV CPYCASGCGL MVYSERDAAG RFVKLLSVQG DPDNPINQGG ACSKGAAMFN LREIYEEGTG KQVINPKRVQ KPMYRAPGSD KWEEKDWDWM LDKIADRIKE TRDSSFIHKE KIADGSEIIV NRTEKIASLG GSGLDNEEAY VLSKMMRSLG VVYLETQARI HMM: 127-178 SD KWEEKDWDWM LDKIADRIKE TRDSSFIHKE KIADGSEIIV NRTEKIASLG ALI: 91-151 SKGAAMFN LREIYEEGTG KQVINPKRVQ KPMYRAPGSD KWEEKDWDWM LDKIADRIKE TRD ENV: 47-163 TV CPYCASGCGL MVYSERDAAG RFVKLLSVQG DPDNPINQGG ACSKGAAMFN LREIYEEGTG KQVINPKRVQ KPMYRAPGSD KWEEKDWDWM LDKIADRIKE TRDSSFIHKE KIADG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200
Sequence: MLNLTINGQ AIQVPRGTML LDACQMAGAD VPTFCYDPQL HLAGSCRMCV VEVQGRHNLQ ASCVTPCVDN MVVDTESPAT VEARKIILEL LLARHNINCH VCEKTGECKL QDYCYRYGVD DSRFAGEKGH FTSEDPNPFI ERDYDKCIMC TRCVRACDEI TGAQAISVKD RGHHAKISTV FDGKLADSTC VFCGQCIMVC PVGALSSKVS MNKGRAYQCE KVLTTCTYCG TGCTLELNVK DNQVVGVSSN RDPVYSPVNQ GALCVKGRFG WDFIHSEDRL TTPLIKENGQ FRAASWEEAL DLAASKLKSI KTEYGPDSIA LFSSARVTNE ENYLAQKMMR AAIGTNNVDH CARL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 1-76 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
PF10588: 82-122 ◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
PF14697: 141-203 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF04879: 219-274 ♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF00384: 277-353 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MLNLTINGQ AIQVPRGTML LDACQMAGAD VPTFCYDPQL HLAGSCRMCV VEVQGRHNLQ ASCVTPCVDN MVVDTESPAT VEARKIILEL LLARHNINCH VCEKTGECKL QDYCYRYGVD DSRFAGEKGH FTSEDPNPFI ERDYDKCIMC TRCVRACDEI TGAQAISVKD RGHHAKISTV FDGKLADSTC VFCGQCIMVC PVGALSSKVS MNKGRAYQCE KVLTTCTYCG TGCTLELNVK DNQVVGVSSN RDPVYSPVNQ GALCVKGRFG WDFIHSEDRL TTPLIKENGQ FRAASWEEAL DLAASKLKSI KTEYGPDSIA LFSSARVTNE ENYLAQKMMR AAIGTNNVDH CARL HMM: 108-200 L QDYCYRYGVD DSRFAGEKGH FTSEDPNPFI ERDYDKCIMC TRCVRACDEI TGAQAISVKD RGHHAKISTV FDGKLADSTC VFCGQCIMVC PV ALI: 260-348 ALCVKGRFG WDFIHSEDRL TTPLIKENGQ FRAASWEEAL DLAASKLKSI KTEYGPDSIA LFSSARVTNE ENYLAQKMMR AAIGTNNVDH ENV: 216-352 QCE KVLTTCTYCG TGCTLELNVK DNQVVGVSSN RDPVYSPVNQ GALCVKGRFG WDFIHSEDRL TTPLIKENGQ FRAASWEEAL DLAASKLKSI KTEYGPDSIA LFSSARVTNE ENYLAQKMMR AAIGTNNVDH CARL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MEVNLVKLN INGKEVEAPQ GSTILQAAEL AGIEIPRLCY DPELSKMGSC RLCVVEVKGN RLLPASCVTP ISPGMEVQTE SPAVVEARKT ILELLIANHP LDCLTCDKLG DCKLADYCYE YGVKESPYVG EKHNYAIDNS NPFIIRDLNK CILCGACVRA CEEMTGQDNL SYLHRGFHRK ATTAADVPYI ESDCVFCGQC VAVCPTGALT EKTMAGKARR FNIDRVQTTC PFCGTGCNFD LAVKDGKVIG VLSNPEAPVN GRSLCVKGRF GWDFIYNEKR LTQPLIKKNG QFVEASWDEA FDLIALRFNE IKEKYGPDSF AALSSARCTN EENYLVQKFT RAYMGTNNVD HCART
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 5-80 ◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌
PF10588: 86-125 ◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
PF12838: 148-207 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF04879: 223-276 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00384: 278-353 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MEVNLVKLN INGKEVEAPQ GSTILQAAEL AGIEIPRLCY DPELSKMGSC RLCVVEVKGN RLLPASCVTP ISPGMEVQTE SPAVVEARKT ILELLIANHP LDCLTCDKLG DCKLADYCYE YGVKESPYVG EKHNYAIDNS NPFIIRDLNK CILCGACVRA CEEMTGQDNL SYLHRGFHRK ATTAADVPYI ESDCVFCGQC VAVCPTGALT EKTMAGKARR FNIDRVQTTC PFCGTGCNFD LAVKDGKVIG VLSNPEAPVN GRSLCVKGRF GWDFIYNEKR LTQPLIKKNG QFVEASWDEA FDLIALRFNE IKEKYGPDSF AALSSARCTN EENYLVQKFT RAYMGTNNVD HCART HMM: 101-170 CLTCDKLG DCKLADYCYE YGVKESPYVG EKHNYAIDNS NPFIIRDLNK CILCGACVRA CEEMTGQDNL SY ALI: 254-319 EAPVN GRSLCVKGRF GWDFIYNEKR LTQPLIKKNG QFVEASWDEA FDLIALRFNE IKEKYGPDSF A ENV: 218-349 R FNIDRVQTTC PFCGTGCNFD LAVKDGKVIG VLSNPEAPVN GRSLCVKGRF GWDFIYNEKR LTQPLIKKNG QFVEASWDEA FDLIALRFNE IKEKYGPDSF AALSSARCTN EENYLVQKFT RAYMGTNNVD H Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
No PFAM domains
Sequence: MSIRTMDMQ VLVQKTGDVA KIQQIQNQGN NLRQQEISSN ILQDTNKNTH TVNKTQASEG KQVYKKQDKE KNPPNDKNKK GNSTKKENKE EDQQLDPHRG TNLDILA HMM: 356-446 ALI: 4-100 TMDMQ VLVQKTGDVA KIQQIQNQGN NLRQQEISSN ILQDTNKNTH TVNKTQASEG KQVYKKQDKE KNPPNDKNKK GNSTKKENKE EDQQLDPHRG TN ENV: 2-104 IRTMDMQ VLVQKTGDVA KIQQIQNQGN NLRQQEISSN ILQDTNKNTH TVNKTQASEG KQVYKKQDKE KNPPNDKNKK GNSTKKENKE EDQQLDPHRG TNLDIL Position: 10 20 30 40 50 60 70 80 90 100
Sequence: METSSIKTI LVTAASILVM VITWHLLALM LGHEYILPTP AETARQMIIL VSSAGFWPVV LATIGRGLLG FIISLGLGVI LGLVAGFSKA AYWLLQPWVT VVRSTPVMSV IILAIIWFES NLVPVVVTLL ILFPIIYGNV VAGIMNINKE LLEMARMYKV KTWRIVTELY LPSILPFLLA GASTAMGIAW KVIIAAEILS QPQLGIGTNL MIAKIDFATA QVFAWTVVAI VISFVFEYLI RLIETRLNTW S
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250
PF00528: 76-246 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
Sequence: METSSIKTI LVTAASILVM VITWHLLALM LGHEYILPTP AETARQMIIL VSSAGFWPVV LATIGRGLLG FIISLGLGVI LGLVAGFSKA AYWLLQPWVT VVRSTPVMSV IILAIIWFES NLVPVVVTLL ILFPIIYGNV VAGIMNINKE LLEMARMYKV KTWRIVTELY LPSILPFLLA GASTAMGIAW KVIIAAEILS QPQLGIGTNL MIAKIDFATA QVFAWTVVAI VISFVFEYLI RLIETRLNTW S HMM: 16-117 LVM VITWHLLALM LGHEYILPTP AETARQMIIL VSSAGFWPVV LATIGRGLLG FIISLGLGVI LGLVAGFSKA AYWLLQPWVT VVRSTPVMSV IILAIIWFE ALI: 88-190 A AYWLLQPWVT VVRSTPVMSV IILAIIWFES NLVPVVVTLL ILFPIIYGNV VAGIMNINKE LLEMARMYKV KTWRIVTELY LPSILPFLLA GASTAMGIAW KV ENV: 83-213 AGFSKA AYWLLQPWVT VVRSTPVMSV IILAIIWFES NLVPVVVTLL ILFPIIYGNV VAGIMNINKE LLEMARMYKV KTWRIVTELY LPSILPFLLA GASTAMGIAW KVIIAAEILS QPQLGIGTNL MIAKI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250
Sequence: MTPTTTLHQ SGQIGPIQTK NRIVMPAMGT GLGSINGEVT PQMIHYYEER AAGGVGMIIV ELACVDSPGG KANLTQLGID HPRYIFGLNE LTEAIHAHDC RAMIQLHHAG RQTSEPVTEG IQPVAPSAQA CKLMRVMPRE LSREEIVELK NKFVSAAFYA YKAGFDGVEL HAAHGYLLSQ FLSPYTNQRS DEYGGNTANR ARLLLEIIST IKQKIPQLAL SVRLNIVDFV PGGLEQAEGL EIAALVEKAG ADLINVSNGI YESGQTNIEP VSFQEGWRIH LAEAVKARVK IPVLAGGVIR HPDFANQLLA SGKTDFVWVG RGMLADPHWA VKSLRGQADK IRPCISCNHC IARSFAGVHI RCAVNPFAAR EWRLRDFNRL DGLRVVVVGG GPAGMQAAIS LARAGASVDL MERSSKLGGL LNVASQPPHK ERLAELVNYL IREVELSGVK VHLNTTFTPE MLTDFKADAL VIASGAKPVM PKINGLPSNI SSLEDILSGQ VKINGEKVVI IGGGSSGCEL GEYLADQENN VTIVEQSPQL AVGLENINRL DLLGRIKKKG VKVKTACNVE EILKDGVVVY SLKEEKQEVL TADRIVISCG YRADHELYGA VQDKVKTVFL IGDAYAARGV QESLEEAALV AYRLRKSREQ FPGLEIN
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
PF00724: 11-334 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
PF07992: 382-616 ◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
Sequence: MTPTTTLHQ SGQIGPIQTK NRIVMPAMGT GLGSINGEVT PQMIHYYEER AAGGVGMIIV ELACVDSPGG KANLTQLGID HPRYIFGLNE LTEAIHAHDC RAMIQLHHAG RQTSEPVTEG IQPVAPSAQA CKLMRVMPRE LSREEIVELK NKFVSAAFYA YKAGFDGVEL HAAHGYLLSQ FLSPYTNQRS DEYGGNTANR ARLLLEIIST IKQKIPQLAL SVRLNIVDFV PGGLEQAEGL EIAALVEKAG ADLINVSNGI YESGQTNIEP VSFQEGWRIH LAEAVKARVK IPVLAGGVIR HPDFANQLLA SGKTDFVWVG RGMLADPHWA VKSLRGQADK IRPCISCNHC IARSFAGVHI RCAVNPFAAR EWRLRDFNRL DGLRVVVVGG GPAGMQAAIS LARAGASVDL MERSSKLGGL LNVASQPPHK ERLAELVNYL IREVELSGVK VHLNTTFTPE MLTDFKADAL VIASGAKPVM PKINGLPSNI SSLEDILSGQ VKINGEKVVI IGGGSSGCEL GEYLADQENN VTIVEQSPQL AVGLENINRL DLLGRIKKKG VKVKTACNVE EILKDGVVVY SLKEEKQEVL TADRIVISCG YRADHELYGA VQDKVKTVFL IGDAYAARGV QESLEEAALV AYRLRKSREQ FPGLEIN HMM: 6-48 LHQ SGQIGPIQTK NRIVMPAMGT GLGSINGEVT PQMIHYYEER ALI: 382-422 RVVVVGG GPAGMQAAIS LARAGASVDL MERSSKLGGL LNVA ENV: 376-430 NRL DGLRVVVVGG GPAGMQAAIS LARAGASVDL MERSSKLGGL LNVASQPPHK ER Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MTPTTTLHQ SGQIGPIQTK NRIVMPAMGT GLGSINGEVT PQMIHYYEER AAGGVGMIIV ELACVDSPGG KANLTQLGID HPRYIFGLNE LTEAIHAHDC RAMIQLHHAG RQTSEPVTEG IQPVAPSAQA CKLMRVMPRE LSREEIVELK NKFVSAAFYA YKAGFDGVEL HAAHGYLLSQ FLSPYTNQRS DEYGGNTANR ARLLLEIIST IKQKIPQLAL SVRLNIVDFV PGGLEQAEGL EIAALVEKAG ADLINVSNGI YESGQTNIEP VSFQEGWRIH LAEAVKARVK IPVLAGGVIR HPDFANQLLA SGKTDFVWVG RGMLADPHWA VKSLRGQADK IRPCISCNHC IARSFAGVHI RCAVNPFAAR EWRLRDFNRL DGLRVVVVGG GPAGMQAAIS LARAGASVDL MERSSKLGGL LNVASQPPHK ERLAELVNYL IREVELSGVK VHLNTTFTPE MLTDFKADAL VIASGAKPVM PKINGLPSNI SSLEDILSGQ VKINGEKVVI IGGGSSGCEL GEYLADQENN VTIVEQSPQL AVGLENINRL DLLGRIKKKG VKVKTACNVE EILKDGVVVY SLKEEKQEVL TADRIVISCG YRADHELYGA VQDKVKTVFL IGDAYAARGV QESLEEAALV AYRLRKSREQ FPGLEIN HMM: 149-214 NKFVSAAFYA YKAGFDGVEL HAAHGYLLSQ FLSPYTNQRS DEYGGNTANR ARLLLEIIST IKQKIP ALI: 474-540 AKPVM PKINGLPSNI SSLEDILSGQ VKINGEKVVI IGGGSSGCEL GEYLADQENN VTIVEQSPQL AV ENV: 454-607 TFTPE MLTDFKADAL VIASGAKPVM PKINGLPSNI SSLEDILSGQ VKINGEKVVI IGGGSSGCEL GEYLADQENN VTIVEQSPQL AVGLENINRL DLLGRIKKKG VKVKTACNVE EILKDGVVVY SLKEEKQEVL TADRIVISCG YRADHELYG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650
Sequence: MYDVIILGA GPAGLTAGLY TGRAKLKTLI LEASNIGGNA AWIDQLDNYP GFPEGVSGGE LMDSFYKQAE RFGVETRFEE VIKVESLPEG KKVTTTEGYY MSQAVVITLG AKRRELEVPG EQEFKGSGVS YCATCDAAFF ADCPVAVVGG GDSAVKEALF LADIASKVYL IHRREGFRAN QTAVDKMLAN DKIELKLNKV ITRIEGDGIM RRVVLRDVNT QAEEVLEIEG LFVSIGLVAA ADFLEGLVET RDGYVVTDDE MHTSVEGIFA AGDIRVKQGR QVATAVGDGA QAGIAVTAYL KE
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
PF07992: 1-287 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MYDVIILGA GPAGLTAGLY TGRAKLKTLI LEASNIGGNA AWIDQLDNYP GFPEGVSGGE LMDSFYKQAE RFGVETRFEE VIKVESLPEG KKVTTTEGYY MSQAVVITLG AKRRELEVPG EQEFKGSGVS YCATCDAAFF ADCPVAVVGG GDSAVKEALF LADIASKVYL IHRREGFRAN QTAVDKMLAN DKIELKLNKV ITRIEGDGIM RRVVLRDVNT QAEEVLEIEG LFVSIGLVAA ADFLEGLVET RDGYVVTDDE MHTSVEGIFA AGDIRVKQGR QVATAVGDGA QAGIAVTAYL KE HMM: 6-53 LGA GPAGLTAGLY TGRAKLKTLI LEASNIGGNA AWIDQLDNYP GFPEG ALI: 2-50 DVIILGA GPAGLTAGLY TGRAKLKTLI LEASNIGGNA AWIDQLDNYP GF ENV: 1-53 YDVIILGA GPAGLTAGLY TGRAKLKTLI LEASNIGGNA AWIDQLDNYP GFPEG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MYDVIILGA GPAGLTAGLY TGRAKLKTLI LEASNIGGNA AWIDQLDNYP GFPEGVSGGE LMDSFYKQAE RFGVETRFEE VIKVESLPEG KKVTTTEGYY MSQAVVITLG AKRRELEVPG EQEFKGSGVS YCATCDAAFF ADCPVAVVGG GDSAVKEALF LADIASKVYL IHRREGFRAN QTAVDKMLAN DKIELKLNKV ITRIEGDGIM RRVVLRDVNT QAEEVLEIEG LFVSIGLVAA ADFLEGLVET RDGYVVTDDE MHTSVEGIFA AGDIRVKQGR QVATAVGDGA QAGIAVTAYL KE HMM: 152-223 AVKEALF LADIASKVYL IHRREGFRAN QTAVDKMLAN DKIELKLNKV ITRIEGDGIM RRVVLRDVNT QAEEV ALI: 115-186 EVPG EQEFKGSGVS YCATCDAAFF ADCPVAVVGG GDSAVKEALF LADIASKVYL IHRREGFRAN QTAVDKML ENV: 60-217 MDSFYKQAE RFGVETRFEE VIKVESLPEG KKVTTTEGYY MSQAVVITLG AKRRELEVPG EQEFKGSGVS YCATCDAAFF ADCPVAVVGG GDSAVKEALF LADIASKVYL IHRREGFRAN QTAVDKMLAN DKIELKLNKV ITRIEGDGIM RRVVLRDVN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300
Sequence: MQNTAWEGF VAGHWVDEID VRDFIQLNYM PYTGDGTFLK PPTAKSLDLW DKVKKLLWEE HQKNGVLNID THTVSSITSH KPCYIDRDLE VIVGLQTDEP LKRAIMPMGG IRMVRAATDS YGYELDPEID LIFTHYRKTH NQGVFDVYTP EIRKARKAGI ITGLPDAYGR GRIIGDYRRI ALYGTDFLIK NKIACLKQIE YDVFTDDLIR LREEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDLNIY RTMAFGMAGL SVVADSLSAV KHARVKIIRN SQGLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
PF02901: 16-603 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF01228: 618-725 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MQNTAWEGF VAGHWVDEID VRDFIQLNYM PYTGDGTFLK PPTAKSLDLW DKVKKLLWEE HQKNGVLNID THTVSSITSH KPCYIDRDLE VIVGLQTDEP LKRAIMPMGG IRMVRAATDS YGYELDPEID LIFTHYRKTH NQGVFDVYTP EIRKARKAGI ITGLPDAYGR GRIIGDYRRI ALYGTDFLIK NKIACLKQIE YDVFTDDLIR LREEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDLNIY RTMAFGMAGL SVVADSLSAV KHARVKIIRN SQGLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV HMM: 273-420 LDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QY ALI: 220-368 LKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN ENV: 196-378 QIE YDVFTDDLIR LREEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MQNTAWEGF VAGHWVDEID VRDFIQLNYM PYTGDGTFLK PPTAKSLDLW DKVKKLLWEE HQKNGVLNID THTVSSITSH KPCYIDRDLE VIVGLQTDEP LKRAIMPMGG IRMVRAATDS YGYELDPEID LIFTHYRKTH NQGVFDVYTP EIRKARKAGI ITGLPDAYGR GRIIGDYRRI ALYGTDFLIK NKIACLKQIE YDVFTDDLIR LREEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDLNIY RTMAFGMAGL SVVADSLSAV KHARVKIIRN SQGLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV HMM: 469-560 DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDLNIY RTMAFGMAGL SVVADSLSAV KHARVKIIRN SQGLATDFEV CGEYPSFGNN DP ALI: 402-494 DYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYA ENV: 394-508 LMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDLNIY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MQNTAWEGF VAGHWVDEID VRDFIQLNYM PYTGDGTFLK PPTAKSLDLW DKVKKLLWEE HQKNGVLNID THTVSSITSH KPCYIDRDLE VIVGLQTDEP LKRAIMPMGG IRMVRAATDS YGYELDPEID LIFTHYRKTH NQGVFDVYTP EIRKARKAGI ITGLPDAYGR GRIIGDYRRI ALYGTDFLIK NKIACLKQIE YDVFTDDLIR LREEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDLNIY RTMAFGMAGL SVVADSLSAV KHARVKIIRN SQGLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV HMM: 644-832 PYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV ALI: 553-742 PSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTI ENV: 541-743 GLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MQNTAWEGF VAGHWVDEID VRDFIQLNYM PYTGDGTFLK PPTAKSLDLW DKVKKLLWEE HQKNGVLNID THTVSSITSH KPCYIDRDLE VIVGLQTDEP LKRAIMPMGG IRMVRAATDS YGYELDPEID LIFTHYRKTH NQGVFDVYTP EIRKARKAGI ITGLPDAYGR GRIIGDYRRI ALYGTDFLIK NKIACLKQIE YDVFTDDLIR LREEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDLNIY RTMAFGMAGL SVVADSLSAV KHARVKIIRN SQGLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV HMM: 283-432 RGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALL ALI: 222-369 ELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN L ENV: 206-505 LIR LREEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MQNTAWEGF VAGHWVDEID VRDFIQLNYM PYTGDGTFLK PPTAKSLDLW DKVKKLLWEE HQKNGVLNID THTVSSITSH KPCYIDRDLE VIVGLQTDEP LKRAIMPMGG IRMVRAATDS YGYELDPEID LIFTHYRKTH NQGVFDVYTP EIRKARKAGI ITGLPDAYGR GRIIGDYRRI ALYGTDFLIK NKIACLKQIE YDVFTDDLIR LREEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDLNIY RTMAFGMAGL SVVADSLSAV KHARVKIIRN SQGLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV HMM: 661-847 KALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV ALI: 552-740 YPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FH ENV: 533-744 VKIIRN SQGLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MQNTAWEGF VAGHWVDEID VRDFIQLNYM PYTGDGTFLK PPTAKSLDLW DKVKKLLWEE HQKNGVLNID THTVSSITSH KPCYIDRDLE VIVGLQTDEP LKRAIMPMGG IRMVRAATDS YGYELDPEID LIFTHYRKTH NQGVFDVYTP EIRKARKAGI ITGLPDAYGR GRIIGDYRRI ALYGTDFLIK NKIACLKQIE YDVFTDDLIR LREEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDLNIY RTMAFGMAGL SVVADSLSAV KHARVKIIRN SQGLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV HMM: 66-102 NID THTVSSITSH KPCYIDRDLE VIVGLQTDEP LKRA ALI: 73-110 SSITSH KPCYIDRDLE VIVGLQTDEP LKRAIMPMGG IR ENV: 48-124 W DKVKKLLWEE HQKNGVLNID THTVSSITSH KPCYIDRDLE VIVGLQTDEP LKRAIMPMGG IRMVRAATDS YGYELD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MQNTAWEGF VAGHWVDEID VRDFIQLNYM PYTGDGTFLK PPTAKSLDLW DKVKKLLWEE HQKNGVLNID THTVSSITSH KPCYIDRDLE VIVGLQTDEP LKRAIMPMGG IRMVRAATDS YGYELDPEID LIFTHYRKTH NQGVFDVYTP EIRKARKAGI ITGLPDAYGR GRIIGDYRRI ALYGTDFLIK NKIACLKQIE YDVFTDDLIR LREEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDLNIY RTMAFGMAGL SVVADSLSAV KHARVKIIRN SQGLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV HMM: 260-293 NGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQE ALI: 221-254 KELNEMAE MYGYDISQPA RNAREAVQFV YFGYLG ENV: 210-257 REEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MQNTAWEGF VAGHWVDEID VRDFIQLNYM PYTGDGTFLK PPTAKSLDLW DKVKKLLWEE HQKNGVLNID THTVSSITSH KPCYIDRDLE VIVGLQTDEP LKRAIMPMGG IRMVRAATDS YGYELDPEID LIFTHYRKTH NQGVFDVYTP EIRKARKAGI ITGLPDAYGR GRIIGDYRRI ALYGTDFLIK NKIACLKQIE YDVFTDDLIR LREEVSEQIT ALKELNEMAE MYGYDISQPA RNAREAVQFV YFGYLGSIKE QNGAAMSLGR VSTFLDIYLN RDLKRGDIDE EAAQELIDQF CIKLRMVRFL RTVDYNELFS GDPVWVTESI GGMGIDGRTL VTRTSFRFLH TLNNLGSAPE PNLTVLWSQN LPQPFKEFCA QTSIDTSSIQ YENDDLMRPY WGDDYAIACC VSAMRIGKQM QYFGARANLA KALLYAINGG IDEMLGLQVA PEFKPISGDI LDYDELWDRY DKVLEWLAKT YVNTMNIIHY MHDKYAYERL EFALHDLNIY RTMAFGMAGL SVVADSLSAV KHARVKIIRN SQGLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV HMM: 633-819 ALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV ALI: 553-741 PSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHT ENV: 518-744 L SVVADSLSAV KHARVKIIRN SQGLATDFEV CGEYPSFGNN DPRVDEIAIL VQKTFMEKLA KHPTYRDSKH TLSILTITSN VVYGKKTGST PDGRKAGEPF APGANPMHGR DQRGALASMN SVAKLPYRYA LDGISYTFSI IPKALGREIK ERPRNLRSLL DGYFASGGHH INVNVLEREI LEDAIEHPEK YPQLTIRVSG YAVNFIKLTR EQQLDVINRT FHTIV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
PF00384: 4-332 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF01568: 414-522 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 250-311 MISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQ ALI: 35-96 NVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEA ENV: 12-102 TAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 385-462 HIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGE ALI: 98-175 E DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVN ENV: 93-214 RTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 602-679 ALI: 257-332 HH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNR ENV: 230-337 AINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 821-892 ALI: 412-484 YPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILN ENV: 402-499 KEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA A Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 245-330 LGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LT ALI: 10-96 DATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEA ENV: 1-97 TNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 401-481 FKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTD ALI: 97-177 FE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPL ENV: 95-185 EAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 602-700 ALI: 241-335 ALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGY ENV: 209-342 EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 841-922 ALI: 412-494 YPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHF ENV: 400-516 EFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 253-314 DPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAII ALI: 35-96 NVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEA ENV: 26-97 PII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 386-470 IGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RR ALI: 97-183 FE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNV ENV: 95-193 EAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 609-684 ALI: 261-334 EALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLG ENV: 256-346 QHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSIDELE KDATAIFLIG TNTTENHPII GYKIRKNVRE NGAKLIVADP RRIELAEIAD VYMQFRPGTD VALLNGMMNV IINEGLLDQK FITERTEAFE DMKQIVEKYT PEVVAAITGV PAADIRKAAR IYAEAEAGSI CYAMGLTQHH TGTDNVKSVC NLAMLTGHLG RPGTGVNPLR GQNNVQGACD MGALPVSYPA YQAVSADANR EKFEKAWGVK LSPHNGLTLT AAINKAYQGE LKALYVLGEN PMISDPDQHH VEEALDNLEF LIVQDIFLSE TAQKADLILP GVSWAEKDGT FSNTERRVQR VRQAIIPPAN SRQDWQILMD LTNRLGYSMD YGSPQDIFEE IRTVAPSYAG ISYARIERTG LHWPCPNEEH PGTPILHIGK FSRGQGLFHP VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEAA ANILTHAEVL DPVAGIPEYK VCAARLEKIV HMM: 838-906 ALI: 412-481 YPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTD ENV: 399-497 VEFKEPFELP DEEYPLILST GRSLFHYHTG TMTRRTQALD AHQPTNEVQV NHHTAAALGI QDGEMVRLST RRGSIELKAK LTDILNEKVV FTFFHFSEA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MEEWKKSSC TLCAQNCGLE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILRSITGRF CVEGGQMYPA FLFPMGGDSD ERNPKTWRTV KHNMFPIMGV FPPAILPDEI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELPGYLYEA GKKGITSYLG AMGAFINENP QHLKIVPLIM AETLGYALGS VNQALIVGLL VGSSKAFKVG AAAMGYPTDQ TMVETIFNDI LAHPQGLMLA KFQGDNFNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN ELVKSTDRDE MCTPMHRRIY CRVEKL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
PF04879: 2-55 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00384: 58-474 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
PF01568: 634-730 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MEEWKKSSC TLCAQNCGLE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILRSITGRF CVEGGQMYPA FLFPMGGDSD ERNPKTWRTV KHNMFPIMGV FPPAILPDEI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELPGYLYEA GKKGITSYLG AMGAFINENP QHLKIVPLIM AETLGYALGS VNQALIVGLL VGSSKAFKVG AAAMGYPTDQ TMVETIFNDI LAHPQGLMLA KFQGDNFNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN ELVKSTDRDE MCTPMHRRIY CRVEKL HMM: 103-309 GGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML H ALI: 39-245 QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHV ENV: 14-253 NCGLE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MEEWKKSSC TLCAQNCGLE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILRSITGRF CVEGGQMYPA FLFPMGGDSD ERNPKTWRTV KHNMFPIMGV FPPAILPDEI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELPGYLYEA GKKGITSYLG AMGAFINENP QHLKIVPLIM AETLGYALGS VNQALIVGLL VGSSKAFKVG AAAMGYPTDQ TMVETIFNDI LAHPQGLMLA KFQGDNFNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN ELVKSTDRDE MCTPMHRRIY CRVEKL HMM: 585-644 FNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRN ALI: 378-436 A LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTT ENV: 370-476 NDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MEEWKKSSC TLCAQNCGLE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILRSITGRF CVEGGQMYPA FLFPMGGDSD ERNPKTWRTV KHNMFPIMGV FPPAILPDEI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELPGYLYEA GKKGITSYLG AMGAFINENP QHLKIVPLIM AETLGYALGS VNQALIVGLL VGSSKAFKVG AAAMGYPTDQ TMVETIFNDI LAHPQGLMLA KFQGDNFNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN ELVKSTDRDE MCTPMHRRIY CRVEKL HMM: 791-902 ALI: 594-704 KIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGG ENV: 577-720 LA KFQGDNFNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN EL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MEEWKKSSC TLCAQNCGLE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILRSITGRF CVEGGQMYPA FLFPMGGDSD ERNPKTWRTV KHNMFPIMGV FPPAILPDEI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELPGYLYEA GKKGITSYLG AMGAFINENP QHLKIVPLIM AETLGYALGS VNQALIVGLL VGSSKAFKVG AAAMGYPTDQ TMVETIFNDI LAHPQGLMLA KFQGDNFNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN ELVKSTDRDE MCTPMHRRIY CRVEKL HMM: 122-328 LGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILRSITGRF CVEGGQMYPA ALI: 39-245 QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHV ENV: 17-249 LE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW D Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MEEWKKSSC TLCAQNCGLE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILRSITGRF CVEGGQMYPA FLFPMGGDSD ERNPKTWRTV KHNMFPIMGV FPPAILPDEI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELPGYLYEA GKKGITSYLG AMGAFINENP QHLKIVPLIM AETLGYALGS VNQALIVGLL VGSSKAFKVG AAAMGYPTDQ TMVETIFNDI LAHPQGLMLA KFQGDNFNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN ELVKSTDRDE MCTPMHRRIY CRVEKL HMM: 602-700 LLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YI ALI: 378-477 A LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGF ENV: 367-502 EI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELPGYLYEA GKKGITSYLG AMGA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MEEWKKSSC TLCAQNCGLE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILRSITGRF CVEGGQMYPA FLFPMGGDSD ERNPKTWRTV KHNMFPIMGV FPPAILPDEI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELPGYLYEA GKKGITSYLG AMGAFINENP QHLKIVPLIM AETLGYALGS VNQALIVGLL VGSSKAFKVG AAAMGYPTDQ TMVETIFNDI LAHPQGLMLA KFQGDNFNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN ELVKSTDRDE MCTPMHRRIY CRVEKL HMM: 838-915 ALI: 621-697 PAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGC ENV: 612-713 NSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MEEWKKSSC TLCAQNCGLE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILRSITGRF CVEGGQMYPA FLFPMGGDSD ERNPKTWRTV KHNMFPIMGV FPPAILPDEI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELPGYLYEA GKKGITSYLG AMGAFINENP QHLKIVPLIM AETLGYALGS VNQALIVGLL VGSSKAFKVG AAAMGYPTDQ TMVETIFNDI LAHPQGLMLA KFQGDNFNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN ELVKSTDRDE MCTPMHRRIY CRVEKL HMM: 100-312 YMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILR ALI: 33-245 KDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHV ENV: 17-251 LE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DEL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MEEWKKSSC TLCAQNCGLE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILRSITGRF CVEGGQMYPA FLFPMGGDSD ERNPKTWRTV KHNMFPIMGV FPPAILPDEI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELPGYLYEA GKKGITSYLG AMGAFINENP QHLKIVPLIM AETLGYALGS VNQALIVGLL VGSSKAFKVG AAAMGYPTDQ TMVETIFNDI LAHPQGLMLA KFQGDNFNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN ELVKSTDRDE MCTPMHRRIY CRVEKL HMM: 591-680 EDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KA ALI: 382-472 SSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELI ENV: 367-482 EI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MEEWKKSSC TLCAQNCGLE MMVEDNRIKK VRGDKDNPRS QGYCCRKGLS IAHAIHNADR IHYPMKKLGD HHERISWEQA IKEISEKMLA IREQHGSKAF AYMGGGSSGG QMEVGVGLRL LNLLGSRYYY SPLAQEFSNV YWVDGRIAGK QGLITLPDPH RADTIVAWGW NGWMSHQEPR TRELIKEIKA NPNRRLIVVD PRLSETAERA DIHLALRPGT DTMLLKAMIQ IILNNRWEDR AFIQEHVNGW DELEPLFEDF DAKRAVEEVC ALDYALVIEA TRLIAQTKSC IHQDLGIYMN RNSTINNYML HILRSITGRF CVEGGQMYPA FLFPMGGDSD ERNPKTWRTV KHNMFPIMGV FPPAILPDEI LNDHPDHIRA LIVSSCNPLR SYPDTLAYEK AFEALELSVC LEINYSETAR LSDYILPCRS YMEMYDTTCF NFSYPELFFQ MRQPVLVPLS DESKENAAIM LELIKAMGFL PELPGYLYEA GKKGITSYLG AMGAFINENP QHLKIVPLIM AETLGYALGS VNQALIVGLL VGSSKAFKVG AAAMGYPTDQ TMVETIFNDI LAHPQGLMLA KFQGDNFNML RTEDKKIALK IEELLEPLKA ATINSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN ELVKSTDRDE MCTPMHRRIY CRVEKL HMM: 834-919 ALI: 620-704 MPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGG ENV: 612-726 NSELESL TMPAKYPMIL HSGLHHETVA NTNMRNPEWN KSRRWATMLV NEADAVRLGL TDGEKARIVT KASSAEIEVE ISPRAAAGCV YIRHGGGLIY DGKKYGVNVN ELVKSTDR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDFTLTEEQ IMIKKMARDF ADNEILPYCQ EWDAKDTFPY DTVKKLHDLG LMTIGVPAEY GGSGLDHLSQ GIVVEEIARG DAGLATTLAA STLLAADPVY VAANDEQKKW FYGRMNEGDL AAFCLTEPGA GSDAGGLSTK CVKDGDDYIL NGTKQFISNG GVAGLYTVFA TLDKKLGYKG HCAFMVDRNT PGITIGPKED KLGIRSSNTT QVIFEDVRVP SKNLLGKEGE GFKICMKTLD LSRAVVAAMA VGVAQGAFEC AVKYSKERQQ FGQPICRFQA IQFILADMAM QVETARLLYQ KACALQDMGL PYTQMSSLAK CWAGDAAMKV ATDAVQVYGG YGYSKEYPVE KYFRDAKIMQ IFEGTAQIQR LVIANDILKE
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-117 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 120-216 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 227-376 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
Sequence: MDFTLTEEQ IMIKKMARDF ADNEILPYCQ EWDAKDTFPY DTVKKLHDLG LMTIGVPAEY GGSGLDHLSQ GIVVEEIARG DAGLATTLAA STLLAADPVY VAANDEQKKW FYGRMNEGDL AAFCLTEPGA GSDAGGLSTK CVKDGDDYIL NGTKQFISNG GVAGLYTVFA TLDKKLGYKG HCAFMVDRNT PGITIGPKED KLGIRSSNTT QVIFEDVRVP SKNLLGKEGE GFKICMKTLD LSRAVVAAMA VGVAQGAFEC AVKYSKERQQ FGQPICRFQA IQFILADMAM QVETARLLYQ KACALQDMGL PYTQMSSLAK CWAGDAAMKV ATDAVQVYGG YGYSKEYPVE KYFRDAKIMQ IFEGTAQIQR LVIANDILKE HMM: 50-386 MTIGVPAEY GGSGLDHLSQ GIVVEEIARG DAGLATTLAA STLLAADPVY VAANDEQKKW FYGRMNEGDL AAFCLTEPGA GSDAGGLSTK CVKDGDDYIL NGTKQFISNG GVAGLYTVFA TLDKKLGYKG HCAFMVDRNT PGITIGPKED KLGIRSSNTT QVIFEDVRVP SKNLLGKEGE GFKICMKTLD LSRAVVAAMA VGVAQGAFEC AVKYSKERQQ FGQPICRFQA IQFILADMAM QVETARLLYQ KACALQDMGL PYTQMSSLAK CWAGDAAMKV ATDAVQVYGG YGYSKEYPVE KYFRDAKIMQ IFEGTAQIQR LVIANDILKE ALI: 43-356 KLHDLG LMTIGVPAEY GGSGLDHLSQ GIVVEEIARG DAGLATTLAA STLLAADPVY VAANDEQKKW FYGRMNEGDL AAFCLTEPGA GSDAGGLSTK CVKDGDDYIL NGTKQFISNG GVAGLYTVFA TLDKKLGYKG HCAFMVDRNT PGITIGPKED KLGIRSSNTT QVIFEDVRVP SKNLLGKEGE GFKICMKTLD LSRAVVAAMA VGVAQGAFEC AVKYSKERQQ FGQPICRFQA IQFILADMAM QVETARLLYQ KACALQDMGL PYTQMSSLAK CWAGDAAMKV ATDAVQVYGG YGYSKEYPVE KYFRDAKI ENV: 14-368 MARDF ADNEILPYCQ EWDAKDTFPY DTVKKLHDLG LMTIGVPAEY GGSGLDHLSQ GIVVEEIARG DAGLATTLAA STLLAADPVY VAANDEQKKW FYGRMNEGDL AAFCLTEPGA GSDAGGLSTK CVKDGDDYIL NGTKQFISNG GVAGLYTVFA TLDKKLGYKG HCAFMVDRNT PGITIGPKED KLGIRSSNTT QVIFEDVRVP SKNLLGKEGE GFKICMKTLD LSRAVVAAMA VGVAQGAFEC AVKYSKERQQ FGQPICRFQA IQFILADMAM QVETARLLYQ KACALQDMGL PYTQMSSLAK CWAGDAAMKV ATDAVQVYGG YGYSKEYPVE KYFRDAKIMQ IFEGTAQIQR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MWYMTEERQ LMLNVARDFV QNEVKPVALE IDKSCRFPLE LFKRAGELGF LGVTISEEYG GLGGDQTTLA LIMEEIAKSL PVLTVAIGAH SLLAGGLLEM LGTPEQKKKY LAPAATGEIM LACGSTEGAG GSNQAEFTTR AVLDGDEWVL NGNKVLISNI GVADVYIVLA LTSDIDPATK SGMSCFIVEA GTPGFVIGQP EHKLGWHGSN TGSISFQNCR IPKESLLGPL GGCLQAMFVS ATAEFLSCGP VSLGMAEGAY EMALEYSLER MQKGKSMFDR FQVTRHKLVQ MWGEIESLRA LVYSTYAMRD AGSMELARGR LLKCKGAEVS EYVAREAIQL IGGVGTVVDT GVERFWRDAK VMAIGGASVE ALMDNIAMLI KNKTV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 4-117 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 120-218 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 246-377 ◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MWYMTEERQ LMLNVARDFV QNEVKPVALE IDKSCRFPLE LFKRAGELGF LGVTISEEYG GLGGDQTTLA LIMEEIAKSL PVLTVAIGAH SLLAGGLLEM LGTPEQKKKY LAPAATGEIM LACGSTEGAG GSNQAEFTTR AVLDGDEWVL NGNKVLISNI GVADVYIVLA LTSDIDPATK SGMSCFIVEA GTPGFVIGQP EHKLGWHGSN TGSISFQNCR IPKESLLGPL GGCLQAMFVS ATAEFLSCGP VSLGMAEGAY EMALEYSLER MQKGKSMFDR FQVTRHKLVQ MWGEIESLRA LVYSTYAMRD AGSMELARGR LLKCKGAEVS EYVAREAIQL IGGVGTVVDT GVERFWRDAK VMAIGGASVE ALMDNIAMLI KNKTV HMM: 21-277 EVKPVALE IDKSCRFPLE LFKRAGELGF LGVTISEEYG GLGGDQTTLA LIMEEIAKSL PVLTVAIGAH SLLAGGLLEM LGTPEQKKKY LAPAATGEIM LACGSTEGAG GSNQAEFTTR AVLDGDEWVL NGNKVLISNI GVADVYIVLA LTSDIDPATK SGMSCFIVEA GTPGFVIGQP EHKLGWHGSN TGSISFQNCR IPKESLLGPL GGCLQAMFVS ATAEFLSCGP VSLGMAEGAY EMALEYSLER MQKGKSMFD ALI: 12-266 NVARDFV QNEVKPVALE IDKSCRFPLE LFKRAGELGF LGVTISEEYG GLGGDQTTLA LIMEEIAKSL PVLTVAIGAH SLLAGGLLEM LGTPEQKKKY LAPAATGEIM LACGSTEGAG GSNQAEFTTR AVLDGDEWVL NGNKVLISNI GVADVYIVLA LTSDIDPATK SGMSCFIVEA GTPGFVIGQP EHKLGWHGSN TGSISFQNCR IPKESLLGPL GGCLQAMFVS ATAEFLSCGP VSLGMAEGAY EMALEYSL ENV: 5-278 EERQ LMLNVARDFV QNEVKPVALE IDKSCRFPLE LFKRAGELGF LGVTISEEYG GLGGDQTTLA LIMEEIAKSL PVLTVAIGAH SLLAGGLLEM LGTPEQKKKY LAPAATGEIM LACGSTEGAG GSNQAEFTTR AVLDGDEWVL NGNKVLISNI GVADVYIVLA LTSDIDPATK SGMSCFIVEA GTPGFVIGQP EHKLGWHGSN TGSISFQNCR IPKESLLGPL GGCLQAMFVS ATAEFLSCGP VSLGMAEGAY EMALEYSLER MQKGKSMFDR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MWYMTEERQ LMLNVARDFV QNEVKPVALE IDKSCRFPLE LFKRAGELGF LGVTISEEYG GLGGDQTTLA LIMEEIAKSL PVLTVAIGAH SLLAGGLLEM LGTPEQKKKY LAPAATGEIM LACGSTEGAG GSNQAEFTTR AVLDGDEWVL NGNKVLISNI GVADVYIVLA LTSDIDPATK SGMSCFIVEA GTPGFVIGQP EHKLGWHGSN TGSISFQNCR IPKESLLGPL GGCLQAMFVS ATAEFLSCGP VSLGMAEGAY EMALEYSLER MQKGKSMFDR FQVTRHKLVQ MWGEIESLRA LVYSTYAMRD AGSMELARGR LLKCKGAEVS EYVAREAIQL IGGVGTVVDT GVERFWRDAK VMAIGGASVE ALMDNIAMLI KNKTV HMM: 358-388 K VMAIGGASVE ALMDNIAMLI KNKTV ALI: 331-361 VAREAIQL IGGVGTVVDT GVERFWRDAK VMA ENV: 306-376 MRD AGSMELARGR LLKCKGAEVS EYVAREAIQL IGGVGTVVDT GVERFWRDAK VMAIGGASVE ALMDNIAM Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MFEFTMTPE QIALRDETRE FAKSVSREYI LDMDADKIKY PKEYLKECGK QNLIGLRVPK EYGGRGLGWE EDIIALEELC VNGYMFGCTY GVTGDVVTEA IVHFGTEEQK KKFLIPICKG EKFAAECLTE PRGGSDFFGT TTIATKDGDD YILNGQKRFI VGGEGADYFL VYARTNTEVP PHKGITCFMV EREMGVKTDY LYGLMGCRGG GTARVVFDNV RVPKENVIGK VDGATPIFYQ MMVPERFGTA AMTIGAVRPA LEIATDYSTK RKAFGRTINK FQGVNFKIAD AVTKLDTCRS MMYITAKAVD SGADPNLCRR LVSEGKKFVT EQCWDVANLS MQVMGGIGYT DVYPIEKILR DMRLSMIWVG SNEIMNVIVQ HEWYEERKKE LANNTKRNSE LDALNAFDEE EKIYE
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
PF02771: 6-120 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
PF02770: 125-219 ♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
PF00441: 240-379 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
Sequence: MFEFTMTPE QIALRDETRE FAKSVSREYI LDMDADKIKY PKEYLKECGK QNLIGLRVPK EYGGRGLGWE EDIIALEELC VNGYMFGCTY GVTGDVVTEA IVHFGTEEQK KKFLIPICKG EKFAAECLTE PRGGSDFFGT TTIATKDGDD YILNGQKRFI VGGEGADYFL VYARTNTEVP PHKGITCFMV EREMGVKTDY LYGLMGCRGG GTARVVFDNV RVPKENVIGK VDGATPIFYQ MMVPERFGTA AMTIGAVRPA LEIATDYSTK RKAFGRTINK FQGVNFKIAD AVTKLDTCRS MMYITAKAVD SGADPNLCRR LVSEGKKFVT EQCWDVANLS MQVMGGIGYT DVYPIEKILR DMRLSMIWVG SNEIMNVIVQ HEWYEERKKE LANNTKRNSE LDALNAFDEE EKIYE HMM: 55-277 RVPK EYGGRGLGWE EDIIALEELC VNGYMFGCTY GVTGDVVTEA IVHFGTEEQK KKFLIPICKG EKFAAECLTE PRGGSDFFGT TTIATKDGDD YILNGQKRFI VGGEGADYFL VYARTNTEVP PHKGITCFMV EREMGVKTDY LYGLMGCRGG GTARVVFDNV RVPKENVIGK VDGATPIFYQ MMVPERFGTA AMTIGAVRPA LEIATDYSTK RKAFGRTIN ALI: 50-267 NLIGLRVPK EYGGRGLGWE EDIIALEELC VNGYMFGCTY GVTGDVVTEA IVHFGTEEQK KKFLIPICKG EKFAAECLTE PRGGSDFFGT TTIATKDGDD YILNGQKRFI VGGEGADYFL VYARTNTEVP PHKGITCFMV EREMGVKTDY LYGLMGCRGG GTARVVFDNV RVPKENVIGK VDGATPIFYQ MMVPERFGTA AMTIGAVRPA LEIATDYST ENV: 39-367 PKEYLKECGK QNLIGLRVPK EYGGRGLGWE EDIIALEELC VNGYMFGCTY GVTGDVVTEA IVHFGTEEQK KKFLIPICKG EKFAAECLTE PRGGSDFFGT TTIATKDGDD YILNGQKRFI VGGEGADYFL VYARTNTEVP PHKGITCFMV EREMGVKTDY LYGLMGCRGG GTARVVFDNV RVPKENVIGK VDGATPIFYQ MMVPERFGTA AMTIGAVRPA LEIATDYSTK RKAFGRTINK FQGVNFKIAD AVTKLDTCRS MMYITAKAVD SGADPNLCRR LVSEGKKFVT EQCWDVANLS MQVMGGIGYT DVYPIEKILR DMRLSMIWV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410
Sequence: MFRSTISEQ DRDLVMMVRE LVQTQIAPQA IMYDAQNEDS FDWSAVDILA DHNLLALSIP EEYGGRGLSH LTTTMIIEEI AAGCAGVATV VAANLHAASP LLISGTEEQR RQFLPLLTAQ KARLGGLAMM ENQPNLDILA RSESLEILGS SIYALEDDND DILILNGFKD YVMNGQVASF ITFMFTLPPQ GGKNGIQVAV LPADTPGIRL GRVRHKLGLK YCSTCELIFE DVKLNPEYLI GKPRSGFLIF MQNLDRCLPY VGAIALGVAR SAYDTALAVS KKKFVLGRPS FEESAISFAL VDMAAKLNAA RLSVHLASWL IDQELDSSQA SSKSKIISSR VAQEITTAAM EITGGRAYIR GYPSEKYLRD AKMLSMIDGS EQFHKALIAS QF
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390
PF02771: 7-117 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 153-231 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF00441: 243-389 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
Sequence: MFRSTISEQ DRDLVMMVRE LVQTQIAPQA IMYDAQNEDS FDWSAVDILA DHNLLALSIP EEYGGRGLSH LTTTMIIEEI AAGCAGVATV VAANLHAASP LLISGTEEQR RQFLPLLTAQ KARLGGLAMM ENQPNLDILA RSESLEILGS SIYALEDDND DILILNGFKD YVMNGQVASF ITFMFTLPPQ GGKNGIQVAV LPADTPGIRL GRVRHKLGLK YCSTCELIFE DVKLNPEYLI GKPRSGFLIF MQNLDRCLPY VGAIALGVAR SAYDTALAVS KKKFVLGRPS FEESAISFAL VDMAAKLNAA RLSVHLASWL IDQELDSSQA SSKSKIISSR VAQEITTAAM EITGGRAYIR GYPSEKYLRD AKMLSMIDGS EQFHKALIAS QF HMM: 17-276 RE LVQTQIAPQA IMYDAQNEDS FDWSAVDILA DHNLLALSIP EEYGGRGLSH LTTTMIIEEI AAGCAGVATV VAANLHAASP LLISGTEEQR RQFLPLLTAQ KARLGGLAMM ENQPNLDILA RSESLEILGS SIYALEDDND DILILNGFKD YVMNGQVASF ITFMFTLPPQ GGKNGIQVAV LPADTPGIRL GRVRHKLGLK YCSTCELIFE DVKLNPEYLI GKPRSGFLIF MQNLDRCLPY VGAIALGVAR SAYDTALA ALI: 10-278 RDLVMMVRE LVQTQIAPQA IMYDAQNEDS FDWSAVDILA DHNLLALSIP EEYGGRGLSH LTTTMIIEEI AAGCAGVATV VAANLHAASP LLISGTEEQR RQFLPLLTAQ KARLGGLAMM ENQPNLDILA RSESLEILGS SIYALEDDND DILILNGFKD YVMNGQVASF ITFMFTLPPQ GGKNGIQVAV LPADTPGIRL GRVRHKLGLK YCSTCELIFE DVKLNPEYLI GKPRSGFLIF MQNLDRCLPY VGAIALGVAR SAYDTALAVS ENV: 3-383 STISEQ DRDLVMMVRE LVQTQIAPQA IMYDAQNEDS FDWSAVDILA DHNLLALSIP EEYGGRGLSH LTTTMIIEEI AAGCAGVATV VAANLHAASP LLISGTEEQR RQFLPLLTAQ KARLGGLAMM ENQPNLDILA RSESLEILGS SIYALEDDND DILILNGFKD YVMNGQVASF ITFMFTLPPQ GGKNGIQVAV LPADTPGIRL GRVRHKLGLK YCSTCELIFE DVKLNPEYLI GKPRSGFLIF MQNLDRCLPY VGAIALGVAR SAYDTALAVS KKKFVLGRPS FEESAISFAL VDMAAKLNAA RLSVHLASWL IDQELDSSQA SSKSKIISSR VAQEITTAAM EITGGRAYIR GYPSEKYLRD AKMLSMIDGS EQFHK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390
Sequence: MDFRLTEEQ EMIRQMAAEF AANEITPYAA EWDKADEVPM DTIAKMHDLG LMTIGIPAEY GGDGLDWLSK YLVCEEIGAG DAGTACTLIA STLLASDPIW VGANDEQKKW WYGRSLEGAL CAFCLTEPGA GSDALGMSCK CVKDGNDYIL NGTKQFITNG GIARNFSVFA TLDKKMGNKG ICCFMVDKDF PGVSIGPKED KMGIRSSSTT QVIFEDVRVP SWMMLGGEGQ GVPIMMETLD LSRTAVAAMA TGIATAALNT AIAYANERQQ FGKPIASFQA ISFMLADMAT AVETSHLLYQ KAAWLQDNNL PFKMVSNMAK MWAADTAMKV TTDALQVLGG YGYTKEYPVE KYMRDAKIMQ LFEGTVQIQR MVIGKYLSQN GYVAYA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-116 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
PF02770: 120-216 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 227-374 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌
Sequence: MDFRLTEEQ EMIRQMAAEF AANEITPYAA EWDKADEVPM DTIAKMHDLG LMTIGIPAEY GGDGLDWLSK YLVCEEIGAG DAGTACTLIA STLLASDPIW VGANDEQKKW WYGRSLEGAL CAFCLTEPGA GSDALGMSCK CVKDGNDYIL NGTKQFITNG GIARNFSVFA TLDKKMGNKG ICCFMVDKDF PGVSIGPKED KMGIRSSSTT QVIFEDVRVP SWMMLGGEGQ GVPIMMETLD LSRTAVAAMA TGIATAALNT AIAYANERQQ FGKPIASFQA ISFMLADMAT AVETSHLLYQ KAAWLQDNNL PFKMVSNMAK MWAADTAMKV TTDALQVLGG YGYTKEYPVE KYMRDAKIMQ LFEGTVQIQR MVIGKYLSQN GYVAYA HMM: 28-405 A EWDKADEVPM DTIAKMHDLG LMTIGIPAEY GGDGLDWLSK YLVCEEIGAG DAGTACTLIA STLLASDPIW VGANDEQKKW WYGRSLEGAL CAFCLTEPGA GSDALGMSCK CVKDGNDYIL NGTKQFITNG GIARNFSVFA TLDKKMGNKG ICCFMVDKDF PGVSIGPKED KMGIRSSSTT QVIFEDVRVP SWMMLGGEGQ GVPIMMETLD LSRTAVAAMA TGIATAALNT AIAYANERQQ FGKPIASFQA ISFMLADMAT AVETSHLLYQ KAAWLQDNNL PFKMVSNMAK MWAADTAMKV TTDALQVLGG YGYTKEYPVE KYMRDAKIMQ LFEGTVQIQR MVIGKYLSQN GYVAYA ALI: 21-376 NEITPYAA EWDKADEVPM DTIAKMHDLG LMTIGIPAEY GGDGLDWLSK YLVCEEIGAG DAGTACTLIA STLLASDPIW VGANDEQKKW WYGRSLEGAL CAFCLTEPGA GSDALGMSCK CVKDGNDYIL NGTKQFITNG GIARNFSVFA TLDKKMGNKG ICCFMVDKDF PGVSIGPKED KMGIRSSSTT QVIFEDVRVP SWMMLGGEGQ GVPIMMETLD LSRTAVAAMA TGIATAALNT AIAYANERQQ FGKPIASFQA ISFMLADMAT AVETSHLLYQ KAAWLQDNNL PFKMVSNMAK MWAADTAMKV TTDALQVLGG YGYTKEYPVE KYMRDAKIMQ LFEGTVQIQR MVIGKYLS ENV: 4-383 LTEEQ EMIRQMAAEF AANEITPYAA EWDKADEVPM DTIAKMHDLG LMTIGIPAEY GGDGLDWLSK YLVCEEIGAG DAGTACTLIA STLLASDPIW VGANDEQKKW WYGRSLEGAL CAFCLTEPGA GSDALGMSCK CVKDGNDYIL NGTKQFITNG GIARNFSVFA TLDKKMGNKG ICCFMVDKDF PGVSIGPKED KMGIRSSSTT QVIFEDVRVP SWMMLGGEGQ GVPIMMETLD LSRTAVAAMA TGIATAALNT AIAYANERQQ FGKPIASFQA ISFMLADMAT AVETSHLLYQ KAAWLQDNNL PFKMVSNMAK MWAADTAMKV TTDALQVLGG YGYTKEYPVE KYMRDAKIMQ LFEGTVQIQR MVIGKYLSQN GYVAY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MNFALTDEQ RLLIEQVREL CINELQPYFA SRQKSELEFD LWPLRLLGEL NIVCPTIPKE YGGLGLDIIT TALVIEEIAA CWPGLAAVID TNLHAVQPLL LAGSPEQKEK YLPLLTGPDA GLASFAFTET TGGSDIDAMQ TCARKTKGGF IIDGGKDYVL NAPQANFLTL FAMTNQQNKK SSLRCFIIPR DTFGVKIDKY YDMTTLDYAQ LAKLVFNEAF LDNDAIIKEN ELFSGYLLLS QTFDIGRVLV GATSVGIARA AYEIAKNYAN ERFQFGRPLK RHQAVAHDLV DMATKIQMAR LMTWQACWLI DQGDDYTVAS AMAKFSASQI AQEVTLKASD ILASRAYERG SFIEQLSRDA RVLSTIEGAN NIQKNIIASL IL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-114 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
PF02770: 122-217 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00441: 233-378 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MNFALTDEQ RLLIEQVREL CINELQPYFA SRQKSELEFD LWPLRLLGEL NIVCPTIPKE YGGLGLDIIT TALVIEEIAA CWPGLAAVID TNLHAVQPLL LAGSPEQKEK YLPLLTGPDA GLASFAFTET TGGSDIDAMQ TCARKTKGGF IIDGGKDYVL NAPQANFLTL FAMTNQQNKK SSLRCFIIPR DTFGVKIDKY YDMTTLDYAQ LAKLVFNEAF LDNDAIIKEN ELFSGYLLLS QTFDIGRVLV GATSVGIARA AYEIAKNYAN ERFQFGRPLK RHQAVAHDLV DMATKIQMAR LMTWQACWLI DQGDDYTVAS AMAKFSASQI AQEVTLKASD ILASRAYERG SFIEQLSRDA RVLSTIEGAN NIQKNIIASL IL HMM: 59-290 YGGLGLDIIT TALVIEEIAA CWPGLAAVID TNLHAVQPLL LAGSPEQKEK YLPLLTGPDA GLASFAFTET TGGSDIDAMQ TCARKTKGGF IIDGGKDYVL NAPQANFLTL FAMTNQQNKK SSLRCFIIPR DTFGVKIDKY YDMTTLDYAQ LAKLVFNEAF LDNDAIIKEN ELFSGYLLLS QTFDIGRVLV GATSVGIARA AYEIAKNYAN ERFQFGRPLK RHQAVAHDLV DM ALI: 53-281 PTIPKE YGGLGLDIIT TALVIEEIAA CWPGLAAVID TNLHAVQPLL LAGSPEQKEK YLPLLTGPDA GLASFAFTET TGGSDIDAMQ TCARKTKGGF IIDGGKDYVL NAPQANFLTL FAMTNQQNKK SSLRCFIIPR DTFGVKIDKY YDMTTLDYAQ LAKLVFNEAF LDNDAIIKEN ELFSGYLLLS QTFDIGRVLV GATSVGIARA AYEIAKNYAN ERFQFGRPLK RHQ ENV: 43-293 RLLGEL NIVCPTIPKE YGGLGLDIIT TALVIEEIAA CWPGLAAVID TNLHAVQPLL LAGSPEQKEK YLPLLTGPDA GLASFAFTET TGGSDIDAMQ TCARKTKGGF IIDGGKDYVL NAPQANFLTL FAMTNQQNKK SSLRCFIIPR DTFGVKIDKY YDMTTLDYAQ LAKLVFNEAF LDNDAIIKEN ELFSGYLLLS QTFDIGRVLV GATSVGIARA AYEIAKNYAN ERFQFGRPLK RHQAVAHDLV DMATK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDFGFTKEE ALLQKMAREF AEKHIEPLAE KIDQENEVPK EILEGLAELE LFGVPFPEKY GGADGGYAGY VLAVEQIARC SSGVGMIMSA HTLSVGAIGV FGTEDQKKKY MPPCCQGKQI ASFAFTEPGT GSDPKQITST AVKDGDSYIL NGTKRFISNA NFPGPIVIFA RESESNEITA FIVDKFCEGY SISEPWKKMG MHGGPLLDVY LKDVRVPAEN VLGQIGQGYP ILQMGISFGK VGVSSCALGG MLAAYEEALK YAKEKTHRGA PIAKFQAIQL RIADLAMKYE ASRWLTYRLG YLADNVKNPA VFAKEAALTK TVVCENSADV ARISLDVHGS YGAMEDYKIS RLYRDAIMGP QIEGVTDMQK MIISGVILKG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
PF02771: 5-117 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 120-213 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF00441: 224-375 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
Sequence: MDFGFTKEE ALLQKMAREF AEKHIEPLAE KIDQENEVPK EILEGLAELE LFGVPFPEKY GGADGGYAGY VLAVEQIARC SSGVGMIMSA HTLSVGAIGV FGTEDQKKKY MPPCCQGKQI ASFAFTEPGT GSDPKQITST AVKDGDSYIL NGTKRFISNA NFPGPIVIFA RESESNEITA FIVDKFCEGY SISEPWKKMG MHGGPLLDVY LKDVRVPAEN VLGQIGQGYP ILQMGISFGK VGVSSCALGG MLAAYEEALK YAKEKTHRGA PIAKFQAIQL RIADLAMKYE ASRWLTYRLG YLADNVKNPA VFAKEAALTK TVVCENSADV ARISLDVHGS YGAMEDYKIS RLYRDAIMGP QIEGVTDMQK MIISGVILKG HMM: 23-233 IEPLAE KIDQENEVPK EILEGLAELE LFGVPFPEKY GGADGGYAGY VLAVEQIARC SSGVGMIMSA HTLSVGAIGV FGTEDQKKKY MPPCCQGKQI ASFAFTEPGT GSDPKQITST AVKDGDSYIL NGTKRFISNA NFPGPIVIFA RESESNEITA FIVDKFCEGY SISEPWKKMG MHGGPLLDVY LKDVRVPAEN VLGQIGQGYP ILQMG ALI: 15-223 AREF AEKHIEPLAE KIDQENEVPK EILEGLAELE LFGVPFPEKY GGADGGYAGY VLAVEQIARC SSGVGMIMSA HTLSVGAIGV FGTEDQKKKY MPPCCQGKQI ASFAFTEPGT GSDPKQITST AVKDGDSYIL NGTKRFISNA NFPGPIVIFA RESESNEITA FIVDKFCEGY SISEPWKKMG MHGGPLLDVY LKDVRVPAEN VLGQI ENV: 7-227 EE ALLQKMAREF AEKHIEPLAE KIDQENEVPK EILEGLAELE LFGVPFPEKY GGADGGYAGY VLAVEQIARC SSGVGMIMSA HTLSVGAIGV FGTEDQKKKY MPPCCQGKQI ASFAFTEPGT GSDPKQITST AVKDGDSYIL NGTKRFISNA NFPGPIVIFA RESESNEITA FIVDKFCEGY SISEPWKKMG MHGGPLLDVY LKDVRVPAEN VLGQIGQGY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MDFGFTKEE ALLQKMAREF AEKHIEPLAE KIDQENEVPK EILEGLAELE LFGVPFPEKY GGADGGYAGY VLAVEQIARC SSGVGMIMSA HTLSVGAIGV FGTEDQKKKY MPPCCQGKQI ASFAFTEPGT GSDPKQITST AVKDGDSYIL NGTKRFISNA NFPGPIVIFA RESESNEITA FIVDKFCEGY SISEPWKKMG MHGGPLLDVY LKDVRVPAEN VLGQIGQGYP ILQMGISFGK VGVSSCALGG MLAAYEEALK YAKEKTHRGA PIAKFQAIQL RIADLAMKYE ASRWLTYRLG YLADNVKNPA VFAKEAALTK TVVCENSADV ARISLDVHGS YGAMEDYKIS RLYRDAIMGP QIEGVTDMQK MIISGVILKG HMM: 348-384 S RLYRDAIMGP QIEGVTDMQK MIISGVILKG ALI: 318-354 K TVVCENSADV ARISLDVHGS YGAMEDYKIS RLYRDA ENV: 273-357 FQAIQL RIADLAMKYE ASRWLTYRLG YLADNVKNPA VFAKEAALTK TVVCENSADV ARISLDVHGS YGAMEDYKIS RLYRDAIMG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370
Sequence: MDFKLGEEH EMLRQSVRDF AEGELAPGVA DRDENEYFDR SVFDKMGELG LTGIPFEEKY GGAGMDYLAY AIAVEELGRV DPSAADTLSA HVSLGAWPIL AFGTEEQKSK YLIPLAEGTK LGAFGLTEAG AGSDAIAMTC KADLDGESYV LNGRKIFITN AGAADTYVVF ARTGPKELRS KAFSAFIVEK GTPGFSFGKF EKKMGLRGTQ NCDLVFEDCR IPKENLLGKE GEGFKISMQT LDGGRIGIAA QSVGIAQGAF ELARDYAKQR VQFGKPISAL QAIQFKLADM ALEIKASRLL TYNAAWKKSQ NMDFGIDAAM AKLKASETAN KVANQAVQIH GGYGYTREYP VERIMRDAKI TEIYEGTSEI QRVVISNSIL R
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 6-117 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 121-218 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 229-378 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MDFKLGEEH EMLRQSVRDF AEGELAPGVA DRDENEYFDR SVFDKMGELG LTGIPFEEKY GGAGMDYLAY AIAVEELGRV DPSAADTLSA HVSLGAWPIL AFGTEEQKSK YLIPLAEGTK LGAFGLTEAG AGSDAIAMTC KADLDGESYV LNGRKIFITN AGAADTYVVF ARTGPKELRS KAFSAFIVEK GTPGFSFGKF EKKMGLRGTQ NCDLVFEDCR IPKENLLGKE GEGFKISMQT LDGGRIGIAA QSVGIAQGAF ELARDYAKQR VQFGKPISAL QAIQFKLADM ALEIKASRLL TYNAAWKKSQ NMDFGIDAAM AKLKASETAN KVANQAVQIH GGYGYTREYP VERIMRDAKI TEIYEGTSEI QRVVISNSIL R HMM: 51-293 GIPFEEKY GGAGMDYLAY AIAVEELGRV DPSAADTLSA HVSLGAWPIL AFGTEEQKSK YLIPLAEGTK LGAFGLTEAG AGSDAIAMTC KADLDGESYV LNGRKIFITN AGAADTYVVF ARTGPKELRS KAFSAFIVEK GTPGFSFGKF EKKMGLRGTQ NCDLVFEDCR IPKENLLGKE GEGFKISMQT LDGGRIGIAA QSVGIAQGAF ELARDYAKQR VQFGKPISAL QAIQFKLADM ALEIK ALI: 44-282 MGELG LTGIPFEEKY GGAGMDYLAY AIAVEELGRV DPSAADTLSA HVSLGAWPIL AFGTEEQKSK YLIPLAEGTK LGAFGLTEAG AGSDAIAMTC KADLDGESYV LNGRKIFITN AGAADTYVVF ARTGPKELRS KAFSAFIVEK GTPGFSFGKF EKKMGLRGTQ NCDLVFEDCR IPKENLLGKE GEGFKISMQT LDGGRIGIAA QSVGIAQGAF ELARDYAKQR VQFGKPISAL QAIQ ENV: 15-370 VRDF AEGELAPGVA DRDENEYFDR SVFDKMGELG LTGIPFEEKY GGAGMDYLAY AIAVEELGRV DPSAADTLSA HVSLGAWPIL AFGTEEQKSK YLIPLAEGTK LGAFGLTEAG AGSDAIAMTC KADLDGESYV LNGRKIFITN AGAADTYVVF ARTGPKELRS KAFSAFIVEK GTPGFSFGKF EKKMGLRGTQ NCDLVFEDCR IPKENLLGKE GEGFKISMQT LDGGRIGIAA QSVGIAQGAF ELARDYAKQR VQFGKPISAL QAIQFKLADM ALEIKASRLL TYNAAWKKSQ NMDFGIDAAM AKLKASETAN KVANQAVQIH GGYGYTREYP VERIMRDAKI TEIYEGTSEI QR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDFGLNDEQ RLFKRTFADF SDEVVAPGAA ERDEEEEFDL ECWRKMAELG LAGLIVPEEY GGIAAGTVVY AMAVEEVSRN CASMGVTLSA HTSLCTWPIL HLGNEEHKKR FLPRLASGES LGALGLTEPN AGSDVGATAM TAVKDGNHYI LNGTKIFITN GYYADIYVIL VRTGDKNAKH GNSSYFVVEK GTPGFSFGKK EKKLGIRSSA TYELVFEDCR VPQENLLGNE GDGFKQTMHV LNGGRVGIAA QALGIAEGAY RYALNFALER QQFGKPIFSN QAISFKLADM AMKIQAARNL VYEVAWREDQ GLPYQRQGAF AKCYAGDVAM EVTTEAVQIL GGYGYTREYP VERMMRDAKI TQIYEGTNEI QRLTITNCIK KGDITNYDY
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-218 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 229-375 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
Sequence: MDFGLNDEQ RLFKRTFADF SDEVVAPGAA ERDEEEEFDL ECWRKMAELG LAGLIVPEEY GGIAAGTVVY AMAVEEVSRN CASMGVTLSA HTSLCTWPIL HLGNEEHKKR FLPRLASGES LGALGLTEPN AGSDVGATAM TAVKDGNHYI LNGTKIFITN GYYADIYVIL VRTGDKNAKH GNSSYFVVEK GTPGFSFGKK EKKLGIRSSA TYELVFEDCR VPQENLLGNE GDGFKQTMHV LNGGRVGIAA QALGIAEGAY RYALNFALER QQFGKPIFSN QAISFKLADM AMKIQAARNL VYEVAWREDQ GLPYQRQGAF AKCYAGDVAM EVTTEAVQIL GGYGYTREYP VERMMRDAKI TQIYEGTNEI QRLTITNCIK KGDITNYDY HMM: 35-388 EFDL ECWRKMAELG LAGLIVPEEY GGIAAGTVVY AMAVEEVSRN CASMGVTLSA HTSLCTWPIL HLGNEEHKKR FLPRLASGES LGALGLTEPN AGSDVGATAM TAVKDGNHYI LNGTKIFITN GYYADIYVIL VRTGDKNAKH GNSSYFVVEK GTPGFSFGKK EKKLGIRSSA TYELVFEDCR VPQENLLGNE GDGFKQTMHV LNGGRVGIAA QALGIAEGAY RYALNFALER QQFGKPIFSN QAISFKLADM AMKIQAARNL VYEVAWREDQ GLPYQRQGAF AKCYAGDVAM EVTTEAVQIL GGYGYTREYP VERMMRDAKI TQIYEGTNEI QRLTITNCIK KGDITNYDY ALI: 28-360 A ERDEEEEFDL ECWRKMAELG LAGLIVPEEY GGIAAGTVVY AMAVEEVSRN CASMGVTLSA HTSLCTWPIL HLGNEEHKKR FLPRLASGES LGALGLTEPN AGSDVGATAM TAVKDGNHYI LNGTKIFITN GYYADIYVIL VRTGDKNAKH GNSSYFVVEK GTPGFSFGKK EKKLGIRSSA TYELVFEDCR VPQENLLGNE GDGFKQTMHV LNGGRVGIAA QALGIAEGAY RYALNFALER QQFGKPIFSN QAISFKLADM AMKIQAARNL VYEVAWREDQ GLPYQRQGAF AKCYAGDVAM EVTTEAVQIL GGYGYTREYP VERMMRDAKI TQ ENV: 17-369 DF SDEVVAPGAA ERDEEEEFDL ECWRKMAELG LAGLIVPEEY GGIAAGTVVY AMAVEEVSRN CASMGVTLSA HTSLCTWPIL HLGNEEHKKR FLPRLASGES LGALGLTEPN AGSDVGATAM TAVKDGNHYI LNGTKIFITN GYYADIYVIL VRTGDKNAKH GNSSYFVVEK GTPGFSFGKK EKKLGIRSSA TYELVFEDCR VPQENLLGNE GDGFKQTMHV LNGGRVGIAA QALGIAEGAY RYALNFALER QQFGKPIFSN QAISFKLADM AMKIQAARNL VYEVAWREDQ GLPYQRQGAF AKCYAGDVAM EVTTEAVQIL GGYGYTREYP VERMMRDAKI TQIYEGTNEI Q Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MNFELNDEQ IMFRKMVRDF AENEVAPSAA TRDEEERFDM EIFYQMGELG ICGIPWDEEY GGAGADYIFY AIAVEELSRV CASTGVTLSA HTSLCSWPIY RFGTHEQKMK YLKPLAEGIQ LGAFGITEPS AGSDAGGTKC TAKKDGNSYI LNGTKIFITN AFYADTYIVI ARTGPKELGS KGISAFIVEK DTPGFSFGKK EKKMGIKSSA TYELVFEDCR IPAENLLGKE GEGFKIGMMI LDGGRTGIAA QALGIAQGAY EYALDYARQR VQFGKPISEL QSVRFKLADM ATQIEAARLL VYQAAYMESN DIPYGKASAM AKVFAGDTAM AVTTEAVQIL GGYGYTREYP VERMMRDAKI TQIYEGTNEI QRVVIANSIL R
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-117 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 121-218 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 229-378 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MNFELNDEQ IMFRKMVRDF AENEVAPSAA TRDEEERFDM EIFYQMGELG ICGIPWDEEY GGAGADYIFY AIAVEELSRV CASTGVTLSA HTSLCSWPIY RFGTHEQKMK YLKPLAEGIQ LGAFGITEPS AGSDAGGTKC TAKKDGNSYI LNGTKIFITN AFYADTYIVI ARTGPKELGS KGISAFIVEK DTPGFSFGKK EKKMGIKSSA TYELVFEDCR IPAENLLGKE GEGFKIGMMI LDGGRTGIAA QALGIAQGAY EYALDYARQR VQFGKPISEL QSVRFKLADM ATQIEAARLL VYQAAYMESN DIPYGKASAM AKVFAGDTAM AVTTEAVQIL GGYGYTREYP VERMMRDAKI TQIYEGTNEI QRVVIANSIL R HMM: 59-289 GGAGADYIFY AIAVEELSRV CASTGVTLSA HTSLCSWPIY RFGTHEQKMK YLKPLAEGIQ LGAFGITEPS AGSDAGGTKC TAKKDGNSYI LNGTKIFITN AFYADTYIVI ARTGPKELGS KGISAFIVEK DTPGFSFGKK EKKMGIKSSA TYELVFEDCR IPAENLLGKE GEGFKIGMMI LDGGRTGIAA QALGIAQGAY EYALDYARQR VQFGKPISEL QSVRFKLADM A ALI: 52-278 IPWDEEY GGAGADYIFY AIAVEELSRV CASTGVTLSA HTSLCSWPIY RFGTHEQKMK YLKPLAEGIQ LGAFGITEPS AGSDAGGTKC TAKKDGNSYI LNGTKIFITN AFYADTYIVI ARTGPKELGS KGISAFIVEK DTPGFSFGKK EKKMGIKSSA TYELVFEDCR IPAENLLGKE GEGFKIGMMI LDGGRTGIAA QALGIAQGAY EYALDYARQR VQFGKPISEL ENV: 13-372 KMVRDF AENEVAPSAA TRDEEERFDM EIFYQMGELG ICGIPWDEEY GGAGADYIFY AIAVEELSRV CASTGVTLSA HTSLCSWPIY RFGTHEQKMK YLKPLAEGIQ LGAFGITEPS AGSDAGGTKC TAKKDGNSYI LNGTKIFITN AFYADTYIVI ARTGPKELGS KGISAFIVEK DTPGFSFGKK EKKMGIKSSA TYELVFEDCR IPAENLLGKE GEGFKIGMMI LDGGRTGIAA QALGIAQGAY EYALDYARQR VQFGKPISEL QSVRFKLADM ATQIEAARLL VYQAAYMESN DIPYGKASAM AKVFAGDTAM AVTTEAVQIL GGYGYTREYP VERMMRDAKI TQIYEGTNEI QRVV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MPAFILSQE ENQLIKEVRE LANGKIKERG TYLDKIGDDK IDWQIPEVLA KHNLLAPNIP AEYGGRGLSM LATAHVIEEL AFGCAGAAAI VVMNIYSLTP VLVTGSEAMK NEILPKFCSD RPHLGCTAIS ETTPEHDLEP SQRLRADETR ITTTAALEGD WITINGTKDF IMNGAAADFV VVLARSKESK RKSRIQMYLV PRKTPGLEVV RVLNKVGMRS CHTVQLRFND VVIPADNRIG IAGGGYFLLT QTFDRNLPLI GAAGIGIARA AYELAMEVAR TNRMLNRDAL LKKYVSSALV EMSTEIDAAR LAVERAAYYI DTDDNFARAA YMAKLYATRT AQRVAFQTVD IIGRMGFAVS YNAEKYLRDA QMLSMIAGSE YLHKTVLAGQ L
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390
PF02771: 7-118 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 146-230 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
PF00441: 243-387 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MPAFILSQE ENQLIKEVRE LANGKIKERG TYLDKIGDDK IDWQIPEVLA KHNLLAPNIP AEYGGRGLSM LATAHVIEEL AFGCAGAAAI VVMNIYSLTP VLVTGSEAMK NEILPKFCSD RPHLGCTAIS ETTPEHDLEP SQRLRADETR ITTTAALEGD WITINGTKDF IMNGAAADFV VVLARSKESK RKSRIQMYLV PRKTPGLEVV RVLNKVGMRS CHTVQLRFND VVIPADNRIG IAGGGYFLLT QTFDRNLPLI GAAGIGIARA AYELAMEVAR TNRMLNRDAL LKKYVSSALV EMSTEIDAAR LAVERAAYYI DTDDNFARAA YMAKLYATRT AQRVAFQTVD IIGRMGFAVS YNAEKYLRDA QMLSMIAGSE YLHKTVLAGQ L HMM: 49-325 KHNLLAPNIP AEYGGRGLSM LATAHVIEEL AFGCAGAAAI VVMNIYSLTP VLVTGSEAMK NEILPKFCSD RPHLGCTAIS ETTPEHDLEP SQRLRADETR ITTTAALEGD WITINGTKDF IMNGAAADFV VVLARSKESK RKSRIQMYLV PRKTPGLEVV RVLNKVGMRS CHTVQLRFND VVIPADNRIG IAGGGYFLLT QTFDRNLPLI GAAGIGIARA AYELAMEVAR TNRMLNRDAL LKKYVSSALV EMSTEIDAAR LAVERAAYYI DTDDNFA ALI: 45-321 EVLA KHNLLAPNIP AEYGGRGLSM LATAHVIEEL AFGCAGAAAI VVMNIYSLTP VLVTGSEAMK NEILPKFCSD RPHLGCTAIS ETTPEHDLEP SQRLRADETR ITTTAALEGD WITINGTKDF IMNGAAADFV VVLARSKESK RKSRIQMYLV PRKTPGLEVV RVLNKVGMRS CHTVQLRFND VVIPADNRIG IAGGGYFLLT QTFDRNLPLI GAAGIGIARA AYELAMEVAR TNRMLNRDAL LKKYVSSALV EMSTEIDAAR LAVERAAYYI DTD ENV: 6-382 SQE ENQLIKEVRE LANGKIKERG TYLDKIGDDK IDWQIPEVLA KHNLLAPNIP AEYGGRGLSM LATAHVIEEL AFGCAGAAAI VVMNIYSLTP VLVTGSEAMK NEILPKFCSD RPHLGCTAIS ETTPEHDLEP SQRLRADETR ITTTAALEGD WITINGTKDF IMNGAAADFV VVLARSKESK RKSRIQMYLV PRKTPGLEVV RVLNKVGMRS CHTVQLRFND VVIPADNRIG IAGGGYFLLT QTFDRNLPLI GAAGIGIARA AYELAMEVAR TNRMLNRDAL LKKYVSSALV EMSTEIDAAR LAVERAAYYI DTDDNFARAA YMAKLYATRT AQRVAFQTVD IIGRMGFAVS YNAEKYLRDA QMLSMIAGSE YLHK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390
Sequence: MNLLLNPKQ YQDRHYPDER SKEIMLQTIQ WFEEKGLAKQ KEQYHNKQFA EDFQAFMTEE GFFETLFLPA GYGSDPHQYY STYRMYEFSE ICGFYGAAYW YCYHVSTLGL DPVLMGDNEE AKHLAAAKLK ENAFCAFGLS EKEHGADIYA TEMMLYPQDD GTYLANGSKY YIGNGNVAST ISVFGKMADT GEYVFFVVDS AHPNYKLVKN IVDVNQQYVA EFELQDYPIT KAEILTVGPK AWDDMLNTIN VCKFNIGSGA TGIVTHSFYE AINHAFHRHL YGQRVTDFPH VKRLFADAWL RIMGMKLFGL RATDYMRVAS ENDKRYLLYN PIMKMKVAIQ GEKVHELLFD IIAAKGFEKD MYFEQAVTEL TGFPKLEGTR HVNMALIAKL IPSYMFMPGE FEEVGKITDN RDDTFLFHQG RTRGYAQTKF HDYMIAYRRL AHLPNVQVYI EQIEAYKAYL ALSGRELARQ MTDFDYLLAV GELFTMVAYG QLIIESAQLE GVGDAVMNQL FDVFVRDFSA YAMELYGKPL NTEGQAEAIQ KMFRRPIPNP EEFAKVLEEE VYSLADVYTQ NP
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570
PF02770: 134-206 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 240-388 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MNLLLNPKQ YQDRHYPDER SKEIMLQTIQ WFEEKGLAKQ KEQYHNKQFA EDFQAFMTEE GFFETLFLPA GYGSDPHQYY STYRMYEFSE ICGFYGAAYW YCYHVSTLGL DPVLMGDNEE AKHLAAAKLK ENAFCAFGLS EKEHGADIYA TEMMLYPQDD GTYLANGSKY YIGNGNVAST ISVFGKMADT GEYVFFVVDS AHPNYKLVKN IVDVNQQYVA EFELQDYPIT KAEILTVGPK AWDDMLNTIN VCKFNIGSGA TGIVTHSFYE AINHAFHRHL YGQRVTDFPH VKRLFADAWL RIMGMKLFGL RATDYMRVAS ENDKRYLLYN PIMKMKVAIQ GEKVHELLFD IIAAKGFEKD MYFEQAVTEL TGFPKLEGTR HVNMALIAKL IPSYMFMPGE FEEVGKITDN RDDTFLFHQG RTRGYAQTKF HDYMIAYRRL AHLPNVQVYI EQIEAYKAYL ALSGRELARQ MTDFDYLLAV GELFTMVAYG QLIIESAQLE GVGDAVMNQL FDVFVRDFSA YAMELYGKPL NTEGQAEAIQ KMFRRPIPNP EEFAKVLEEE VYSLADVYTQ NP HMM: 92-193 FYGAAYW YCYHVSTLGL DPVLMGDNEE AKHLAAAKLK ENAFCAFGLS EKEHGADIYA TEMMLYPQDD GTYLANGSKY YIGNGNVAST ISVFGKMADT GEYVF ALI: 98-202 W YCYHVSTLGL DPVLMGDNEE AKHLAAAKLK ENAFCAFGLS EKEHGADIYA TEMMLYPQDD GTYLANGSKY YIGNGNVAST ISVFGKMADT GEYVFFVVDS AHPN ENV: 58-220 E GFFETLFLPA GYGSDPHQYY STYRMYEFSE ICGFYGAAYW YCYHVSTLGL DPVLMGDNEE AKHLAAAKLK ENAFCAFGLS EKEHGADIYA TEMMLYPQDD GTYLANGSKY YIGNGNVAST ISVFGKMADT GEYVFFVVDS AHPNYKLVKN IVDVNQQYVA EF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570
Sequence: MSANFINST RDHKFILKEW LNLEQVLATP RFKGGYSVDD IDFILDNALK GAREVVAPTC EEADQIGSRF ENGHAFMPSA CKEAYHFIQQ NGFCSSNKNK NDPSAVPLSV MWSMMEYMIG ANPHLGTILA GPAAAGEVLE EFGSDYLQRT YVDKMFSGEW TATMCLTEPG AGSDVGDLLT RAYPTGEPGV YNIKGTKCFI SHAENGICDN TIHLVLARIE GAAPGTKGLS LFVIPQFFSD EDGHITEPND VSVSGIEHKL GLKGNATCVL NFGEEGKCKG WLVGDPPGED GVGAGMKQMF KVMNEERLMT GHAALSLAAV AYHNAVAYSQ ERIQGRPLTD PKGERVPILQ HEDVRRMLLF QKSHIEVFRA MIINNFYLLD LAYNSPDKNL ARYCANLAEV NIPIIKAYCS DMAIECISTA MQCYGGYGFS EEYPIAELYR DCRIYPIWEG TNYIQAMDLV GRKFTLGKGQ VFADWLKEIT DFVNKNEGTN GFEREFALMA EALQNYQGIL ATLGNYIGEN KISMMPLFAT RILHATGKLL GGKLILDQAL LAQSKINQLG SEHFDYAFYN GKIAAARFYV RNIVPEIGTT LSIFKDGDTS ALDIMEEAFL V
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
PF12418: 9-31 ♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF02770: 162-271 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF00441: 291-458 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
PF12806: 473-603 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MSANFINST RDHKFILKEW LNLEQVLATP RFKGGYSVDD IDFILDNALK GAREVVAPTC EEADQIGSRF ENGHAFMPSA CKEAYHFIQQ NGFCSSNKNK NDPSAVPLSV MWSMMEYMIG ANPHLGTILA GPAAAGEVLE EFGSDYLQRT YVDKMFSGEW TATMCLTEPG AGSDVGDLLT RAYPTGEPGV YNIKGTKCFI SHAENGICDN TIHLVLARIE GAAPGTKGLS LFVIPQFFSD EDGHITEPND VSVSGIEHKL GLKGNATCVL NFGEEGKCKG WLVGDPPGED GVGAGMKQMF KVMNEERLMT GHAALSLAAV AYHNAVAYSQ ERIQGRPLTD PKGERVPILQ HEDVRRMLLF QKSHIEVFRA MIINNFYLLD LAYNSPDKNL ARYCANLAEV NIPIIKAYCS DMAIECISTA MQCYGGYGFS EEYPIAELYR DCRIYPIWEG TNYIQAMDLV GRKFTLGKGQ VFADWLKEIT DFVNKNEGTN GFEREFALMA EALQNYQGIL ATLGNYIGEN KISMMPLFAT RILHATGKLL GGKLILDQAL LAQSKINQLG SEHFDYAFYN GKIAAARFYV RNIVPEIGTT LSIFKDGDTS ALDIMEEAFL V HMM: 87-167 QQ NGFCSSNKNK NDPSAVPLSV MWSMMEYMIG ANPHLGTILA GPAAAGEVLE EFGSDYLQRT YVDKMFSGEW TATMCLTEP ALI: 121-204 PHLGTILA GPAAAGEVLE EFGSDYLQRT YVDKMFSGEW TATMCLTEPG AGSDVGDLLT RAYPTGEPGV YNIKGTKCFI SHAENG ENV: 108-239 V MWSMMEYMIG ANPHLGTILA GPAAAGEVLE EFGSDYLQRT YVDKMFSGEW TATMCLTEPG AGSDVGDLLT RAYPTGEPGV YNIKGTKCFI SHAENGICDN TIHLVLARIE GAAPGTKGLS LFVIPQFFSD E Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MSANFINST RDHKFILKEW LNLEQVLATP RFKGGYSVDD IDFILDNALK GAREVVAPTC EEADQIGSRF ENGHAFMPSA CKEAYHFIQQ NGFCSSNKNK NDPSAVPLSV MWSMMEYMIG ANPHLGTILA GPAAAGEVLE EFGSDYLQRT YVDKMFSGEW TATMCLTEPG AGSDVGDLLT RAYPTGEPGV YNIKGTKCFI SHAENGICDN TIHLVLARIE GAAPGTKGLS LFVIPQFFSD EDGHITEPND VSVSGIEHKL GLKGNATCVL NFGEEGKCKG WLVGDPPGED GVGAGMKQMF KVMNEERLMT GHAALSLAAV AYHNAVAYSQ ERIQGRPLTD PKGERVPILQ HEDVRRMLLF QKSHIEVFRA MIINNFYLLD LAYNSPDKNL ARYCANLAEV NIPIIKAYCS DMAIECISTA MQCYGGYGFS EEYPIAELYR DCRIYPIWEG TNYIQAMDLV GRKFTLGKGQ VFADWLKEIT DFVNKNEGTN GFEREFALMA EALQNYQGIL ATLGNYIGEN KISMMPLFAT RILHATGKLL GGKLILDQAL LAQSKINQLG SEHFDYAFYN GKIAAARFYV RNIVPEIGTT LSIFKDGDTS ALDIMEEAFL V HMM: 321-397 HNAVAYSQ ERIQGRPLTD PKGERVPILQ HEDVRRMLLF QKSHIEVFRA MIINNFYLLD LAYNSPDKNL ARYCANLAE ALI: 376-453 LLD LAYNSPDKNL ARYCANLAEV NIPIIKAYCS DMAIECISTA MQCYGGYGFS EEYPIAELYR DCRIYPIWEG TNYIQ ENV: 306-469 LMT GHAALSLAAV AYHNAVAYSQ ERIQGRPLTD PKGERVPILQ HEDVRRMLLF QKSHIEVFRA MIINNFYLLD LAYNSPDKNL ARYCANLAEV NIPIIKAYCS DMAIECISTA MQCYGGYGFS EEYPIAELYR DCRIYPIWEG TNYIQAMDLV GRKFTLGKGQ V Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MSYKFAYNT RDIKFILKEW LPTEEILAYD KYKDYYTLDD FDTIIDQVRK VAAEVIAPTA EDADNIGARW ENGQVYLPPS FHTAIRFMHE NGWATSNLDD EAEGVLPIVL NSLLFEIEAA ANPALFAYMA TGSGVANVLK HYGSDEQKQR FLPKLFEGTW GGTMCLTEPT AGSDVGELLS KAYPTDEPGI YKMKGQKIFI TCGDRDDVEN IIHLYLARVD GAKNGTKGLS LFIVPKFWVD ENGNLTPNDV QCIGIEHKMG LKGSATCALV VGENNNCRGW LIGNPPDENG VGEGIMQMFN MMNEARLDTG RLSTAVAANA YWNAKDYGKE RIQGRLLTDP KAGKVTINKH EDVKRMYLLN KATTEACRAL LAKCYFYDDV SENDPDPERR KWARKKMDML TPLCKAYPSD EAWGLVAESL QSYGGYGYCE DYPAANSARD CKIWSIWEGT NFIQSMDLIG RKWMAGKGAI FASVLGEIDE FLAQYKGKIE GMDQEMIHLE KALAAYREIQ MTIGGYVGAG KLGLMAVYAR RILTATAQTY CGFLLMDQAR IAKERLAELP ADHYDYNFYL GKVLSARYYL NNAVPNVWHI LELIKIGDMS VIDAPIEIFD Y
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
PF02771: 41-157 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 162-269 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
PF00441: 291-456 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
PF12806: 473-603 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MSYKFAYNT RDIKFILKEW LPTEEILAYD KYKDYYTLDD FDTIIDQVRK VAAEVIAPTA EDADNIGARW ENGQVYLPPS FHTAIRFMHE NGWATSNLDD EAEGVLPIVL NSLLFEIEAA ANPALFAYMA TGSGVANVLK HYGSDEQKQR FLPKLFEGTW GGTMCLTEPT AGSDVGELLS KAYPTDEPGI YKMKGQKIFI TCGDRDDVEN IIHLYLARVD GAKNGTKGLS LFIVPKFWVD ENGNLTPNDV QCIGIEHKMG LKGSATCALV VGENNNCRGW LIGNPPDENG VGEGIMQMFN MMNEARLDTG RLSTAVAANA YWNAKDYGKE RIQGRLLTDP KAGKVTINKH EDVKRMYLLN KATTEACRAL LAKCYFYDDV SENDPDPERR KWARKKMDML TPLCKAYPSD EAWGLVAESL QSYGGYGYCE DYPAANSARD CKIWSIWEGT NFIQSMDLIG RKWMAGKGAI FASVLGEIDE FLAQYKGKIE GMDQEMIHLE KALAAYREIQ MTIGGYVGAG KLGLMAVYAR RILTATAQTY CGFLLMDQAR IAKERLAELP ADHYDYNFYL GKVLSARYYL NNAVPNVWHI LELIKIGDMS VIDAPIEIFD Y HMM: 93-169 TSNLDD EAEGVLPIVL NSLLFEIEAA ANPALFAYMA TGSGVANVLK HYGSDEQKQR FLPKLFEGTW GGTMCLTEPT A ALI: 124-206 FAYMA TGSGVANVLK HYGSDEQKQR FLPKLFEGTW GGTMCLTEPT AGSDVGELLS KAYPTDEPGI YKMKGQKIFI TCGDRDDV ENV: 111-255 LLFEIEAA ANPALFAYMA TGSGVANVLK HYGSDEQKQR FLPKLFEGTW GGTMCLTEPT AGSDVGELLS KAYPTDEPGI YKMKGQKIFI TCGDRDDVEN IIHLYLARVD GAKNGTKGLS LFIVPKFWVD ENGNLTPNDV QCIGIEH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610
Sequence: MHKNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAMDTLDY TGRTYNQGSK AILLGIGAPI RKLPGEYQGG SLPGITKIKT YCAGCLLVSG QTFDQGPELA AQIARQEIPD LCDWPLVILV DDVDHIKDQT SFLWTVFTRF DPAMDIYAQQ ELRQNYIHYE LPIIIDARMK GMYPADLEPR EDIVRQVDKR WKEYFG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580
PF01977: 8-422 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MHKNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAMDTLDY TGRTYNQGSK AILLGIGAPI RKLPGEYQGG SLPGITKIKT YCAGCLLVSG QTFDQGPELA AQIARQEIPD LCDWPLVILV DDVDHIKDQT SFLWTVFTRF DPAMDIYAQQ ELRQNYIHYE LPIIIDARMK GMYPADLEPR EDIVRQVDKR WKEYFG HMM: 3-410 NLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FN ALI: 2-423 KNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAM ENV: 1-450 HKNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAMDTLDY TGRTYNQGSK AILLGIGAPI RK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580
Sequence: MHKNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAMDTLDY TGRTYNQGSK AILLGIGAPI RKLPGEYQGG SLPGITKIKT YCAGCLLVSG QTFDQGPELA AQIARQEIPD LCDWPLVILV DDVDHIKDQT SFLWTVFTRF DPAMDIYAQQ ELRQNYIHYE LPIIIDARMK GMYPADLEPR EDIVRQVDKR WKEYFG HMM: 372-408 FRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR ALI: 504-540 LVILV DDVDHIKDQT SFLWTVFTRF DPAMDIYAQQ EL ENV: 464-583 TKIKT YCAGCLLVSG QTFDQGPELA AQIARQEIPD LCDWPLVILV DDVDHIKDQT SFLWTVFTRF DPAMDIYAQQ ELRQNYIHYE LPIIIDARMK GMYPADLEPR EDIVRQVDKR WKEYF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580
Sequence: MHKNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAMDTLDY TGRTYNQGSK AILLGIGAPI RKLPGEYQGG SLPGITKIKT YCAGCLLVSG QTFDQGPELA AQIARQEIPD LCDWPLVILV DDVDHIKDQT SFLWTVFTRF DPAMDIYAQQ ELRQNYIHYE LPIIIDARMK GMYPADLEPR EDIVRQVDKR WKEYFG HMM: 1-320 HKNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YY ALI: 1-330 HKNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IA ENV: 1-443 HKNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAMDTLDY TGRTYNQGSK AILLG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580
Sequence: MHKNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAMDTLDY TGRTYNQGSK AILLGIGAPI RKLPGEYQGG SLPGITKIKT YCAGCLLVSG QTFDQGPELA AQIARQEIPD LCDWPLVILV DDVDHIKDQT SFLWTVFTRF DPAMDIYAQQ ELRQNYIHYE LPIIIDARMK GMYPADLEPR EDIVRQVDKR WKEYFG HMM: 4-442 LRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAMDTLDY TGRTYNQGSK AILL ALI: 3-445 NLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAMDTLDY TGRTYNQGSK AILLGIG ENV: 1-457 HKNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAMDTLDY TGRTYNQGSK AILLGIGAPI RKLPGEYQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580
Sequence: MHKNLRSFI AQLKKEKQIV EVPAQVDPYL ELAEVHRRVV ENDGPALLFT NVKGSRFPVA TNLFGSMERM EMAIGTRPEE IIGSAISSLD KLLPPRFNSL WEERHWLLDL LKLGTKPVTA RQAPVMEKRI KNINLYELPV ITSWQEDGGP FFTLPLVYTE KPGTKEHNLG MYRMQVYSAN QTGMHWQIHK GGGFHYHAAE QRGQNLPVTV FLGGPPALTV AAITALPEPV PELLYASFLL GSKINTVQTP DHPHPLIAEA EFALCGQVPA GIRHPEGPFG DHYGYYSLVH DFPVFNVKQL YHRKDAIYPA TIVGKPRQED YYIGEWMQEL IAPLFPLIMP GLKSMWTYAE AGFHTLCAAV VRESYYREAL AHGFRILGEG QLSLTKVLLI TNVEQDLKNF AELLENILLR FNPSRDLIII NQTAMDTLDY TGRTYNQGSK AILLGIGAPI RKLPGEYQGG SLPGITKIKT YCAGCLLVSG QTFDQGPELA AQIARQEIPD LCDWPLVILV DDVDHIKDQT SFLWTVFTRF DPAMDIYAQQ ELRQNYIHYE LPIIIDARMK GMYPADLEPR EDIVRQVDKR WKEYFG HMM: 386-417 LLI TNVEQDLKNF AELLENILLR FNPSRDLII ALI: 505-536 VILV DDVDHIKDQT SFLWTVFTRF DPAMDIYA ENV: 499-546 LCDWPLVILV DDVDHIKDQT SFLWTVFTRF DPAMDIYAQQ ELRQNYIH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580
Sequence: MKTRRTNII LLVVFLGLIL FSLGINKGAE FAGADEQAEE VIAQINPDYE PWFNPLWEPP SGEIESLLFA VQAALGCGFI CFYFGYKYGQ KGKTAEVSSE RN
10 20 30 40 50 60 70 80 90 100
PF02553: 6-73 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
Sequence: MKTRRTNII LLVVFLGLIL FSLGINKGAE FAGADEQAEE VIAQINPDYE PWFNPLWEPP SGEIESLLFA VQAALGCGFI CFYFGYKYGQ KGKTAEVSSE RN HMM: 90-119 GKTAEVSSE RN ALI: 70-99 QAALGCGFI CFYFGYKYGQ KGKTAEVSSE R ENV: 64-101 SLLFA VQAALGCGFI CFYFGYKYGQ KGKTAEVSSE RN Position: 10 20 30 40 50 60 70 80 90 100
Sequence: MQVFKHIND MQAWSQAQKK QGLTIGLVPT MGYLHAGHLS LVQAAREQCD RVIVSIFVNP TQFGAGEDFA DYPRDIERDC ELLRQAQTDA VFAPDAREMY AQDFNTWVEV KGEITAKLCG ASRPNHFKGV TTVVSKLFNI CLPDRAFFGQ KDVQQAMIIE KMVRELNFPL SIVRVPIMRE ASGLAMSSRN VYLSSEQKEQ ALVLSQSLQK AAQLIAAGER NPAHIKGVIR DMIAQSPEAV IDYAEIYDAH GLSDVEVVQG SVLIALAVKF GTTRLIDNLI VEV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280
PF02569: 1-278 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MQVFKHIND MQAWSQAQKK QGLTIGLVPT MGYLHAGHLS LVQAAREQCD RVIVSIFVNP TQFGAGEDFA DYPRDIERDC ELLRQAQTDA VFAPDAREMY AQDFNTWVEV KGEITAKLCG ASRPNHFKGV TTVVSKLFNI CLPDRAFFGQ KDVQQAMIIE KMVRELNFPL SIVRVPIMRE ASGLAMSSRN VYLSSEQKEQ ALVLSQSLQK AAQLIAAGER NPAHIKGVIR DMIAQSPEAV IDYAEIYDAH GLSDVEVVQG SVLIALAVKF GTTRLIDNLI VEV HMM: 267-319 KF GTTRLIDNLI VEV ALI: 56-110 VNP TQFGAGEDFA DYPRDIERDC ELLRQAQTDA VFAPDAREMY AQDFNTWVEV KG ENV: 28-135 T MGYLHAGHLS LVQAAREQCD RVIVSIFVNP TQFGAGEDFA DYPRDIERDC ELLRQAQTDA VFAPDAREMY AQDFNTWVEV KGEITAKLCG ASRPNHFKGV TTVVSKL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
PF00384: 2-333 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF01568: 415-521 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 254-309 DPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ P ALI: 38-93 K GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERC ENV: 26-96 VIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 384-462 VLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADG ALI: 96-175 FDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVN ENV: 81-232 EGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 600-679 ALI: 257-333 QH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANR ENV: 244-339 YVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW N Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 820-897 ALI: 412-490 EYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VF ENV: 404-508 PPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 274-328 DIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM ALI: 39-93 GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERC ENV: 25-96 PVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 402-480 YTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KI ALI: 97-176 DE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNP ENV: 94-185 EGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 632-701 ALI: 270-337 LVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMN ENV: 240-353 LKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 841-914 ALI: 413-485 YPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPK ENV: 405-499 PAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET C Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 258-313 H HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKV ALI: 39-94 GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCE ENV: 31-96 IKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 387-471 KD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRR ALI: 97-184 DE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQ ENV: 94-212 EGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 614-686 ALI: 267-337 LE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMN ENV: 258-371 H HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSIREVP VSEGYLLIGT NTTDNHPVIG SMIKAQVVNK GKKLIVADPR RIELAKYADY FFQIKPGTNI AILNGFMHVL VKEGLYDRKY VAERCEGFDE LAKTLEKYTP EYVAEICGLE NGEDIPKAAR LMAACKPFAL YYAMGITQFI SGVNGVKSTA NLQMLMGNLG IPGGGVNPLR GQNNVQGACD MGALNAVYPA YQTVASEENK AKFEKAWGAS GLSMKPGLTV VEMFNAAIAG QLKAAYVMGE NPVVSDPNQH HIIEGLNALE FLVVQDIVLT ETAQYADVVL PAYAFLEKEG TATNTERRVQ PMHKVVAPWG EARDDWWIIM QIANRMGMNW NYGKAEDIFE EIRTVTPSYA GITYDRIEKE LIQWPCPTED HPGTQVLHKD KFSRGLGLLT AIDYTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANVLTIDAL DPVCKIPEYK VCSCKIEKIY L HMM: 837-921 ALI: 412-498 EYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET ENV: 402-502 YTPPAEE TDSEYPLILT TGRLLEHFHT GTMSRNSRIL DEIVPEGYVE LNPNEASNYN IADGEVISVS TRRGSIRIKA KISEKPKAGV VFMPFHFFET CANV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
PF00384: 1-332 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF01568: 415-521 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 246-311 ENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTV ALI: 29-94 TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDN ENV: 8-96 A NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 366-462 TDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGE ALI: 76-173 VLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVN ENV: 68-194 A FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 621-678 ALI: 275-330 PTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AK ENV: 266-340 EFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 820-897 ALI: 412-489 EYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV W ENV: 403-515 APPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 243-330 IFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AK ALI: 7-94 FA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDN ENV: 1-95 TNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 402-480 WAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VT ALI: 96-174 EAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNP ENV: 94-183 NFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 644-702 ALI: 280-336 RFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEW ENV: 269-349 VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE V Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 840-927 ALI: 412-495 EYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFR ENV: 402-511 WAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 248-314 L ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTP ALI: 28-94 S TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDN ENV: 2-96 NSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 387-465 DG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVK ALI: 96-173 EAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVN ENV: 94-193 NFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 614-689 ALI: 265-338 AEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS ENV: 229-354 MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MTNSFGEFA NAKMFFCIGT NMTEAHPVAS TFLKNAVRNG AKLIVADPRK QPLVDFADIH CQIRVGSDIA FLNGIMNVLI TENLYDKKFV EQKCDNFEAF KAKILEYPPE RAAEISGVSV EQIREVARLL ASVKPAMLCY TLGITEHTTG KDNVMSTANL QLLLGNLGMP SAGVNPLRGQ NNVQGACDMG ALPNVFPGYQ KVIDPAARAK FEKAWGVEKL PENNGLMIPQ MMEGLVDKSV RAFYIFGENL ANTEPDIHKV EHELASAEFL VCQDIFPTET TRFAHVVFPA AAWSEDDGTF SSSERRVNRV RTVKTPPGDA RPNWWIFREL AKRMGQEWTS SSSQEIWDNE VSVLAPALGG IKYRRIETDG LQWPCPTEDH PGTAFLHRDG IFTHGKGIFN PVDWAPPAEV PDAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD PVTKTAEYKA CAVNVEKL HMM: 871-916 ALI: 446-491 ADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMA ENV: 410-508 DAEYPFVLS TGRRLFHYHT RTQTGRSGMN LILSEETADI SPADAQKLGI AQGEYVKVSS RRGEVKVRAK VTEQVPAGMV WMAFHFREGC ANWLTNAVYD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520
Sequence: MDFALSEEL EMLRSMARDF AAEKIAPFAD KWDEEHYFPY EEVVKPMGEL GFFGTVIPEE YGGTNMGWLA AMILTEEISR ASSALRVQIN MEGLGCAYTI WKYGTEEAKK KYVQKLVSAE YLGGFGITEF NAGSDVMSMK STAEDKGDYY LLNGSKTWIS NANCADVIIY YAYTDKAAKG KGLSAFAVEL KNNPGIRTTD LDKMGSKSSP TGEIYLDNVK VPKENLLGKP GDGAKIVFGS LNGTRLSAAA GGIGLAQACL DAAIKYANER EQFGKPIGTF QANQFLIGEM ATELEAARLM VYRAAWQKDQ GNLGNTVETA QAKYLAGEVA YKCAIGAMRI FGAYGYSTEY PVNRYYRDAP TYAMVEGSTN VCKMIVGGAL LAQK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-119 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
PF02770: 122-218 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 229-379 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
Sequence: MDFALSEEL EMLRSMARDF AAEKIAPFAD KWDEEHYFPY EEVVKPMGEL GFFGTVIPEE YGGTNMGWLA AMILTEEISR ASSALRVQIN MEGLGCAYTI WKYGTEEAKK KYVQKLVSAE YLGGFGITEF NAGSDVMSMK STAEDKGDYY LLNGSKTWIS NANCADVIIY YAYTDKAAKG KGLSAFAVEL KNNPGIRTTD LDKMGSKSSP TGEIYLDNVK VPKENLLGKP GDGAKIVFGS LNGTRLSAAA GGIGLAQACL DAAIKYANER EQFGKPIGTF QANQFLIGEM ATELEAARLM VYRAAWQKDQ GNLGNTVETA QAKYLAGEVA YKCAIGAMRI FGAYGYSTEY PVNRYYRDAP TYAMVEGSTN VCKMIVGGAL LAQK HMM: 56-391 PEE YGGTNMGWLA AMILTEEISR ASSALRVQIN MEGLGCAYTI WKYGTEEAKK KYVQKLVSAE YLGGFGITEF NAGSDVMSMK STAEDKGDYY LLNGSKTWIS NANCADVIIY YAYTDKAAKG KGLSAFAVEL KNNPGIRTTD LDKMGSKSSP TGEIYLDNVK VPKENLLGKP GDGAKIVFGS LNGTRLSAAA GGIGLAQACL DAAIKYANER EQFGKPIGTF QANQFLIGEM ATELEAARLM VYRAAWQKDQ GNLGNTVETA QAKYLAGEVA YKCAIGAMRI FGAYGYSTEY PVNRYYRDAP TYAMVEGSTN VCKMIVGGAL LAQK ALI: 50-364 FFGTVIPEE YGGTNMGWLA AMILTEEISR ASSALRVQIN MEGLGCAYTI WKYGTEEAKK KYVQKLVSAE YLGGFGITEF NAGSDVMSMK STAEDKGDYY LLNGSKTWIS NANCADVIIY YAYTDKAAKG KGLSAFAVEL KNNPGIRTTD LDKMGSKSSP TGEIYLDNVK VPKENLLGKP GDGAKIVFGS LNGTRLSAAA GGIGLAQACL DAAIKYANER EQFGKPIGTF QANQFLIGEM ATELEAARLM VYRAAWQKDQ GNLGNTVETA QAKYLAGEVA YKCAIGAMRI FGAYGYSTEY PVNRYYRDAP TYAMVE ENV: 40-379 EVVKPMGEL GFFGTVIPEE YGGTNMGWLA AMILTEEISR ASSALRVQIN MEGLGCAYTI WKYGTEEAKK KYVQKLVSAE YLGGFGITEF NAGSDVMSMK STAEDKGDYY LLNGSKTWIS NANCADVIIY YAYTDKAAKG KGLSAFAVEL KNNPGIRTTD LDKMGSKSSP TGEIYLDNVK VPKENLLGKP GDGAKIVFGS LNGTRLSAAA GGIGLAQACL DAAIKYANER EQFGKPIGTF QANQFLIGEM ATELEAARLM VYRAAWQKDQ GNLGNTVETA QAKYLAGEVA YKCAIGAMRI FGAYGYSTEY PVNRYYRDAP TYAMVEGSTN VCKMIVGGAL L Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MNELTEEQK LLMEMVRNLA VREIAPRAIE IDENHSFPVH ARDLFADLGL LSPLVPVEYG GTGMDITTFA MVLEEIGKVC ASTALMLLAQ ADGMLSIILD GSPALKEKYL PRFGEKSTLM TAFAATEPGA GSDLLAMKTR AVKKGDKYVI NGQKCFITNG SVADILTVWA YTDPSKGAKG MSTFVVERGT PGLIYGHNEK KMGMRGCPNS ELFFEDLEVP AENLVGEEGK GFAYLMGALS INRVFCASQA VGIAQGALER AMQHTREREQ FGKPIAHLTP IQFMIADMAT EVEAARLLVR KATTLLDAKD KRGPLIGGMA KTFASDTAMK VTTDAVQVMG GSGYMQEYQV ERMMREAKLT QIYTGTNQIT RMVTGRSLLF PS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 4-112 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF02770: 120-215 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00441: 227-377 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MNELTEEQK LLMEMVRNLA VREIAPRAIE IDENHSFPVH ARDLFADLGL LSPLVPVEYG GTGMDITTFA MVLEEIGKVC ASTALMLLAQ ADGMLSIILD GSPALKEKYL PRFGEKSTLM TAFAATEPGA GSDLLAMKTR AVKKGDKYVI NGQKCFITNG SVADILTVWA YTDPSKGAKG MSTFVVERGT PGLIYGHNEK KMGMRGCPNS ELFFEDLEVP AENLVGEEGK GFAYLMGALS INRVFCASQA VGIAQGALER AMQHTREREQ FGKPIAHLTP IQFMIADMAT EVEAARLLVR KATTLLDAKD KRGPLIGGMA KTFASDTAMK VTTDAVQVMG GSGYMQEYQV ERMMREAKLT QIYTGTNQIT RMVTGRSLLF PS HMM: 22-387 IAPRAIE IDENHSFPVH ARDLFADLGL LSPLVPVEYG GTGMDITTFA MVLEEIGKVC ASTALMLLAQ ADGMLSIILD GSPALKEKYL PRFGEKSTLM TAFAATEPGA GSDLLAMKTR AVKKGDKYVI NGQKCFITNG SVADILTVWA YTDPSKGAKG MSTFVVERGT PGLIYGHNEK KMGMRGCPNS ELFFEDLEVP AENLVGEEGK GFAYLMGALS INRVFCASQA VGIAQGALER AMQHTREREQ FGKPIAHLTP IQFMIADMAT EVEAARLLVR KATTLLDAKD KRGPLIGGMA KTFASDTAMK VTTDAVQVMG GSGYMQEYQV ERMMREAKLT QIYTGTNQIT RMVTGRSLLF PS ALI: 13-358 MVRNLA VREIAPRAIE IDENHSFPVH ARDLFADLGL LSPLVPVEYG GTGMDITTFA MVLEEIGKVC ASTALMLLAQ ADGMLSIILD GSPALKEKYL PRFGEKSTLM TAFAATEPGA GSDLLAMKTR AVKKGDKYVI NGQKCFITNG SVADILTVWA YTDPSKGAKG MSTFVVERGT PGLIYGHNEK KMGMRGCPNS ELFFEDLEVP AENLVGEEGK GFAYLMGALS INRVFCASQA VGIAQGALER AMQHTREREQ FGKPIAHLTP IQFMIADMAT EVEAARLLVR KATTLLDAKD KRGPLIGGMA KTFASDTAMK VTTDAVQVMG GSGYMQEYQV ERMMREAKLT ENV: 4-367 TEEQK LLMEMVRNLA VREIAPRAIE IDENHSFPVH ARDLFADLGL LSPLVPVEYG GTGMDITTFA MVLEEIGKVC ASTALMLLAQ ADGMLSIILD GSPALKEKYL PRFGEKSTLM TAFAATEPGA GSDLLAMKTR AVKKGDKYVI NGQKCFITNG SVADILTVWA YTDPSKGAKG MSTFVVERGT PGLIYGHNEK KMGMRGCPNS ELFFEDLEVP AENLVGEEGK GFAYLMGALS INRVFCASQA VGIAQGALER AMQHTREREQ FGKPIAHLTP IQFMIADMAT EVEAARLLVR KATTLLDAKD KRGPLIGGMA KTFASDTAMK VTTDAVQVMG GSGYMQEYQV ERMMREAKLT QIYTGTNQI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDFSLTAEQ IRFKESVVEF ARRALKNEAL EHGDPREFYW EGWRRCAEFG IQGIAMPKAY GGLELDLLTC VLIMQGLGYA CRDAGLIFSL NTQIWTCECP ILKFGTDEQK EKYLGRLISG SIVGGHAMTE PDSGSDAFSM KTRAVRDGDR YILNGTKIFI TNAPIADILL VFAVTNEQKK FGGVSAFIVE KGFPGFSVGK PFSLMGLRSC PIGEVILQDC EVPAENRLGS EGAGSAIFNS EMEQERSCLF ASQLGAMEKI LEDCVQYAKA RSQFGQPIGD YQAVSHKIAD MRVRIELSRL ILYQVAWMKA SGKRAPVESS IAKLYVSESY VQTCMDALQI HGAYGYSTEF PIERNLRDSI AGKIYSGSSE IQRNILASFL GL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-119 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
PF02770: 124-219 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
PF00441: 231-377 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MDFSLTAEQ IRFKESVVEF ARRALKNEAL EHGDPREFYW EGWRRCAEFG IQGIAMPKAY GGLELDLLTC VLIMQGLGYA CRDAGLIFSL NTQIWTCECP ILKFGTDEQK EKYLGRLISG SIVGGHAMTE PDSGSDAFSM KTRAVRDGDR YILNGTKIFI TNAPIADILL VFAVTNEQKK FGGVSAFIVE KGFPGFSVGK PFSLMGLRSC PIGEVILQDC EVPAENRLGS EGAGSAIFNS EMEQERSCLF ASQLGAMEKI LEDCVQYAKA RSQFGQPIGD YQAVSHKIAD MRVRIELSRL ILYQVAWMKA SGKRAPVESS IAKLYVSESY VQTCMDALQI HGAYGYSTEF PIERNLRDSI AGKIYSGSSE IQRNILASFL GL HMM: 56-252 KAY GGLELDLLTC VLIMQGLGYA CRDAGLIFSL NTQIWTCECP ILKFGTDEQK EKYLGRLISG SIVGGHAMTE PDSGSDAFSM KTRAVRDGDR YILNGTKIFI TNAPIADILL VFAVTNEQKK FGGVSAFIVE KGFPGFSVGK PFSLMGLRSC PIGEVILQDC EVPAENRLGS EGAGSAIFNS EMEQERSCLF ASQL ALI: 49-251 IQGIAMPKAY GGLELDLLTC VLIMQGLGYA CRDAGLIFSL NTQIWTCECP ILKFGTDEQK EKYLGRLISG SIVGGHAMTE PDSGSDAFSM KTRAVRDGDR YILNGTKIFI TNAPIADILL VFAVTNEQKK FGGVSAFIVE KGFPGFSVGK PFSLMGLRSC PIGEVILQDC EVPAENRLGS EGAGSAIFNS EMEQERSCLF ASQ ENV: 42-282 RRCAEFG IQGIAMPKAY GGLELDLLTC VLIMQGLGYA CRDAGLIFSL NTQIWTCECP ILKFGTDEQK EKYLGRLISG SIVGGHAMTE PDSGSDAFSM KTRAVRDGDR YILNGTKIFI TNAPIADILL VFAVTNEQKK FGGVSAFIVE KGFPGFSVGK PFSLMGLRSC PIGEVILQDC EVPAENRLGS EGAGSAIFNS EMEQERSCLF ASQLGAMEKI LEDCVQYAKA RSQFGQPIGD YQAV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDLSLTDTQ QMYVTTVQRF VKNDILPHVL EMDRRHVFPM DLIKTSWEMG IMNISIPESI KGYHVDVVSA ALIIRELAYG DSGIATSAMC NDLANVVIAQ HGTDEQKEAF LRPFVDSPLL SAFCLTEPGA GSDNLSMTSF ISKRDDGKYV LNGSKCFITN ASYASQFTVF CKVGKPSSQL MACVVVPVPP FVLDKASPVD GIREIELASG GKITVGKPED KLGQRLSNTA SVTFEDVLIE PGQIIGDRRL GFKYIIDVLD FARPMIAAIG VGVAKKAFDL TLSYTKERKQ FGQRLCDIPV AREMLVQMWK KVELSELALL KSAIKIQENA TDKGMYSSLA KNEAAEAALF CANEGLHLHG GYGFTNEYEI SKLVRDVHII DIYEGTREVQ NMIIGRELV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390
PF02771: 5-114 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
PF02770: 120-236 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 249-397 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MDLSLTDTQ QMYVTTVQRF VKNDILPHVL EMDRRHVFPM DLIKTSWEMG IMNISIPESI KGYHVDVVSA ALIIRELAYG DSGIATSAMC NDLANVVIAQ HGTDEQKEAF LRPFVDSPLL SAFCLTEPGA GSDNLSMTSF ISKRDDGKYV LNGSKCFITN ASYASQFTVF CKVGKPSSQL MACVVVPVPP FVLDKASPVD GIREIELASG GKITVGKPED KLGQRLSNTA SVTFEDVLIE PGQIIGDRRL GFKYIIDVLD FARPMIAAIG VGVAKKAFDL TLSYTKERKQ FGQRLCDIPV AREMLVQMWK KVELSELALL KSAIKIQENA TDKGMYSSLA KNEAAEAALF CANEGLHLHG GYGFTNEYEI SKLVRDVHII DIYEGTREVQ NMIIGRELV HMM: 54-193 IPESI KGYHVDVVSA ALIIRELAYG DSGIATSAMC NDLANVVIAQ HGTDEQKEAF LRPFVDSPLL SAFCLTEPGA GSDNLSMTSF ISKRDDGKYV LNGSKCFITN ASYASQFTVF CKVGKPSSQL MACVVVPVPP FVLDK ALI: 47-188 MG IMNISIPESI KGYHVDVVSA ALIIRELAYG DSGIATSAMC NDLANVVIAQ HGTDEQKEAF LRPFVDSPLL SAFCLTEPGA GSDNLSMTSF ISKRDDGKYV LNGSKCFITN ASYASQFTVF CKVGKPSSQL MACVVVPVPP ENV: 16-291 QRF VKNDILPHVL EMDRRHVFPM DLIKTSWEMG IMNISIPESI KGYHVDVVSA ALIIRELAYG DSGIATSAMC NDLANVVIAQ HGTDEQKEAF LRPFVDSPLL SAFCLTEPGA GSDNLSMTSF ISKRDDGKYV LNGSKCFITN ASYASQFTVF CKVGKPSSQL MACVVVPVPP FVLDKASPVD GIREIELASG GKITVGKPED KLGQRLSNTA SVTFEDVLIE PGQIIGDRRL GFKYIIDVLD FARPMIAAIG VGVAKKAFDL TLSYTKERKQ FGQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390
Sequence: MYINTETED LKTAIDAIRK AVKDRIAPLA AEVDDSGVIK PEIYDLLWDL GLMTVTYPPE YGGSETNPGT LLCIGCEEIA KACASTALLL IIQAVGSFPL MHGGRKELLD RIAPRIVNNR ELAGYLVSEP GAGSDVKAIR TKAVKDGNDW VINGTKCWAT NGPIASFYSC LCRTKDDKGV QGYSFFLVER NTPGLSVGKI EHKMGMRGSQ TSEVILEDVR VPAENLLGEL NNGFKLAMKD FDMSRPAIAA QALGISEGAF AQMETYSRER YTFGKPLCEH GMITQIIADS AALIEAGRGL IYQAADLYDK GKKNTKLASM AKFFMGDAAV KITTDAIQVF GGYGYTHDYP VERMFRDAKL TQIFEGANQI QRIVVAREIR DEQSK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 6-117 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 123-218 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 229-378 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MYINTETED LKTAIDAIRK AVKDRIAPLA AEVDDSGVIK PEIYDLLWDL GLMTVTYPPE YGGSETNPGT LLCIGCEEIA KACASTALLL IIQAVGSFPL MHGGRKELLD RIAPRIVNNR ELAGYLVSEP GAGSDVKAIR TKAVKDGNDW VINGTKCWAT NGPIASFYSC LCRTKDDKGV QGYSFFLVER NTPGLSVGKI EHKMGMRGSQ TSEVILEDVR VPAENLLGEL NNGFKLAMKD FDMSRPAIAA QALGISEGAF AQMETYSRER YTFGKPLCEH GMITQIIADS AALIEAGRGL IYQAADLYDK GKKNTKLASM AKFFMGDAAV KITTDAIQVF GGYGYTHDYP VERMFRDAKL TQIFEGANQI QRIVVAREIR DEQSK HMM: 24-299 IAPLA AEVDDSGVIK PEIYDLLWDL GLMTVTYPPE YGGSETNPGT LLCIGCEEIA KACASTALLL IIQAVGSFPL MHGGRKELLD RIAPRIVNNR ELAGYLVSEP GAGSDVKAIR TKAVKDGNDW VINGTKCWAT NGPIASFYSC LCRTKDDKGV QGYSFFLVER NTPGLSVGKI EHKMGMRGSQ TSEVILEDVR VPAENLLGEL NNGFKLAMKD FDMSRPAIAA QALGISEGAF AQMETYSRER YTFGKPLCEH GMITQIIADS AALIEAGRGL I ALI: 18-292 K AVKDRIAPLA AEVDDSGVIK PEIYDLLWDL GLMTVTYPPE YGGSETNPGT LLCIGCEEIA KACASTALLL IIQAVGSFPL MHGGRKELLD RIAPRIVNNR ELAGYLVSEP GAGSDVKAIR TKAVKDGNDW VINGTKCWAT NGPIASFYSC LCRTKDDKGV QGYSFFLVER NTPGLSVGKI EHKMGMRGSQ TSEVILEDVR VPAENLLGEL NNGFKLAMKD FDMSRPAIAA QALGISEGAF AQMETYSRER YTFGKPLCEH GMITQIIADS AALI ENV: 4-369 TETED LKTAIDAIRK AVKDRIAPLA AEVDDSGVIK PEIYDLLWDL GLMTVTYPPE YGGSETNPGT LLCIGCEEIA KACASTALLL IIQAVGSFPL MHGGRKELLD RIAPRIVNNR ELAGYLVSEP GAGSDVKAIR TKAVKDGNDW VINGTKCWAT NGPIASFYSC LCRTKDDKGV QGYSFFLVER NTPGLSVGKI EHKMGMRGSQ TSEVILEDVR VPAENLLGEL NNGFKLAMKD FDMSRPAIAA QALGISEGAF AQMETYSRER YTFGKPLCEH GMITQIIADS AALIEAGRGL IYQAADLYDK GKKNTKLASM AKFFMGDAAV KITTDAIQVF GGYGYTHDYP VERMFRDAKL TQIFEGANQI Q Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MEILQYMQE HRIFRETFKK FLAKEIVPHI EEWEEAGIVP RWAWKKMGEQ GFLGMSVPEA YGGPAVDFLY EVVVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKKR YLPGCVSGDI ITAIGMTEPN TGSDLAAIRT TAVADRDEIV LNGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVEA GTPGFEKGRN LKKIGWHSQD TAELFFAECR IPVTNRLGGK GTGFRKMMEM LQQERLVVAI GAQVMAEFML ENTIAYCRER KVFGRPISRF QNSQFEFAEM ATEIEIGRTF LDKMIVEHME GRDLTREMSM AKYWITDMAG RVADRCLQLH GGYGYCEEYP IARAWRDIRI MRIYAGSNEI MKVIIARTLG L
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 7-118 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-218 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 229-378 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MEILQYMQE HRIFRETFKK FLAKEIVPHI EEWEEAGIVP RWAWKKMGEQ GFLGMSVPEA YGGPAVDFLY EVVVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKKR YLPGCVSGDI ITAIGMTEPN TGSDLAAIRT TAVADRDEIV LNGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVEA GTPGFEKGRN LKKIGWHSQD TAELFFAECR IPVTNRLGGK GTGFRKMMEM LQQERLVVAI GAQVMAEFML ENTIAYCRER KVFGRPISRF QNSQFEFAEM ATEIEIGRTF LDKMIVEHME GRDLTREMSM AKYWITDMAG RVADRCLQLH GGYGYCEEYP IARAWRDIRI MRIYAGSNEI MKVIIARTLG L HMM: 47-224 EQ GFLGMSVPEA YGGPAVDFLY EVVVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKKR YLPGCVSGDI ITAIGMTEPN TGSDLAAIRT TAVADRDEIV LNGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVEA GTPGFEKGRN LKKIGWHSQD TAELFFAECR IPVTNR ALI: 41-219 AWKKMGEQ GFLGMSVPEA YGGPAVDFLY EVVVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKKR YLPGCVSGDI ITAIGMTEPN TGSDLAAIRT TAVADRDEIV LNGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVEA GTPGFEKGRN LKKIGWHSQD TAELFFAECR I ENV: 16-260 FKK FLAKEIVPHI EEWEEAGIVP RWAWKKMGEQ GFLGMSVPEA YGGPAVDFLY EVVVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKKR YLPGCVSGDI ITAIGMTEPN TGSDLAAIRT TAVADRDEIV LNGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVEA GTPGFEKGRN LKKIGWHSQD TAELFFAECR IPVTNRLGGK GTGFRKMMEM LQQERLVVAI GAQVMAEFML EN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MEILQYMQE HRIFRETFKK FLAKEIVPHI EEWEEAGIVP RWAWKKMGEQ GFLGMSVPEA YGGPAVDFLY EVVVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKKR YLPGCVSGDI ITAIGMTEPN TGSDLAAIRT TAVADRDEIV LNGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVEA GTPGFEKGRN LKKIGWHSQD TAELFFAECR IPVTNRLGGK GTGFRKMMEM LQQERLVVAI GAQVMAEFML ENTIAYCRER KVFGRPISRF QNSQFEFAEM ATEIEIGRTF LDKMIVEHME GRDLTREMSM AKYWITDMAG RVADRCLQLH GGYGYCEEYP IARAWRDIRI MRIYAGSNEI MKVIIARTLG L HMM: 340-390 GYGYCEEYP IARAWRDIRI MRIYAGSNEI MKVIIARTLG L ALI: 312-362 LTREMSM AKYWITDMAG RVADRCLQLH GGYGYCEEYP IARAWRDIRI MRIY ENV: 294-373 IGRTF LDKMIVEHME GRDLTREMSM AKYWITDMAG RVADRCLQLH GGYGYCEEYP IARAWRDIRI MRIYAGSNEI MKVII Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF00384: 381-471 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
PF01568: 574-676 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET HMM: 124-326 SPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPL ALI: 39-237 LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQ ENV: 18-241 T VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET HMM: 624-701 QVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET ALI: 398-475 R ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLE ENV: 370-479 GERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF P Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET HMM: 867-917 ALI: 589-641 LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIR ENV: 570-650 ISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE ID Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET HMM: 108-310 W GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TG ALI: 39-237 LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQ ENV: 21-240 AGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET HMM: 387-463 AV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQ ALI: 243-318 DELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD ENV: 238-321 Y GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET HMM: 610-684 ISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET ALI: 399-473 ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLG ENV: 375-480 PIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PW Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET HMM: 871-920 ALI: 598-647 V DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWG ENV: 587-651 PS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET HMM: 99-308 AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV ALI: 33-238 LPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY ENV: 4-244 TVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET HMM: 387-467 AV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFE ALI: 245-325 LRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIP ENV: 241-350 GFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET HMM: 585-682 RIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET ALI: 378-474 M LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGL ENV: 371-504 ERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLREN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MQCHTVCRL CSACCPVTVT VEAGKMVRAA RKSFLPEEKR LSCPKLAAAP EIVYSPARIL RPLIRSGPGN GFHEASWDEA LGRVAERFNF FRRTDGAQSI AWLRGMAADW GAPWDYACRL MNAFGSPNTI GNGSVCHVAR EMAHAFTYGA MTLPQPRNSR CILIWGKNDR NTAPGVCEQI LHARSHGARL IVVDPIRTSF AQMADIWLQI KPGHDGPLAM AMLNEIINNN LYDAAFVDQY GIGFDELRAA VAHFSPDLVA ADLWLDPEDI RRAARLYATT RPACIIDGNG LDMQLSTFQA TRAVCMLRAV TGNIDREGGD LIPQPIPLKN IQLKERLPKD VQPVTAAYPL FDAFHPTWGR HAQSCLIDAI LGERPYPIRM LVVQSGNPAV TMTDAKRVRR ALQKLDFLVV IDLFRNRTAE MADVILPAAS CFEKTQLNRA SMRSSPVVLQ NQVIDCLGES RPDWQIVFEL GRRLGLEADF PWASVEAAID EQLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC RIET HMM: 826-906 ALI: 571-650 SGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE ID ENV: 490-679 QLSPSGLTV AFLRENPDGL WTEPTKFEKY RSKGFATPSG RVEFHSDRLA RAGHAPVPFA EGTFEDLPGS ADACNADVVI GISGERTNRF THTQFLRIPS LARQEPEGFV DIHPRDAAAR GISDGQEITI SNERGQVRMK ARISDVVHPG SIRIAWGWGE IDPDANVNNL TDDNRRDPIT ATPSNRSFLC R Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVAKEINGF FLEDKTVENP TKKGEFKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYTD KNMSARRDGK KDPTGIGLYP EWAWAWPVNR RIIYNGASVD PSGKPWSAKK AVIKWVGDKW VGDVPDGVGD PGSGRPPFIM KPDGVASLFG PGLADGPFPE HYEPLECPVE KNFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNINGNILH EVGIPWHFGW ITTKDRQYNP GDKKAEVFTW GDAANLLVPT IGDANTTIPE SKAFMVNVVK K
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
PF00384: 1-373 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF01568: 689-760 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVAKEINGF FLEDKTVENP TKKGEFKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYTD KNMSARRDGK KDPTGIGLYP EWAWAWPVNR RIIYNGASVD PSGKPWSAKK AVIKWVGDKW VGDVPDGVGD PGSGRPPFIM KPDGVASLFG PGLADGPFPE HYEPLECPVE KNFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNINGNILH EVGIPWHFGW ITTKDRQYNP GDKKAEVFTW GDAANLLVPT IGDANTTIPE SKAFMVNVVK K HMM: 246-482 LLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVA ALI: 10-233 SDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMR ENV: 6-242 DIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGST Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVAKEINGF FLEDKTVENP TKKGEFKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYTD KNMSARRDGK KDPTGIGLYP EWAWAWPVNR RIIYNGASVD PSGKPWSAKK AVIKWVGDKW VGDVPDGVGD PGSGRPPFIM KPDGVASLFG PGLADGPFPE HYEPLECPVE KNFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNINGNILH EVGIPWHFGW ITTKDRQYNP GDKKAEVFTW GDAANLLVPT IGDANTTIPE SKAFMVNVVK K HMM: 650-703 NFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH WQTGL ALI: 397-448 LP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE ENV: 394-460 VFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVAKEINGF FLEDKTVENP TKKGEFKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYTD KNMSARRDGK KDPTGIGLYP EWAWAWPVNR RIIYNGASVD PSGKPWSAKK AVIKWVGDKW VGDVPDGVGD PGSGRPPFIM KPDGVASLFG PGLADGPFPE HYEPLECPVE KNFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNINGNILH EVGIPWHFGW ITTKDRQYNP GDKKAEVFTW GDAANLLVPT IGDANTTIPE SKAFMVNVVK K HMM: 868-913 ALI: 712-759 SEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK P ENV: 675-763 VYSG IDSCDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNIN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVAKEINGF FLEDKTVENP TKKGEFKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYTD KNMSARRDGK KDPTGIGLYP EWAWAWPVNR RIIYNGASVD PSGKPWSAKK AVIKWVGDKW VGDVPDGVGD PGSGRPPFIM KPDGVASLFG PGLADGPFPE HYEPLECPVE KNFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNINGNILH EVGIPWHFGW ITTKDRQYNP GDKKAEVFTW GDAANLLVPT IGDANTTIPE SKAFMVNVVK K HMM: 230-320 AAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GA ALI: 10-100 SDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NP ENV: 3-105 HWIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVAKEINGF FLEDKTVENP TKKGEFKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYTD KNMSARRDGK KDPTGIGLYP EWAWAWPVNR RIIYNGASVD PSGKPWSAKK AVIKWVGDKW VGDVPDGVGD PGSGRPPFIM KPDGVASLFG PGLADGPFPE HYEPLECPVE KNFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNINGNILH EVGIPWHFGW ITTKDRQYNP GDKKAEVFTW GDAANLLVPT IGDANTTIPE SKAFMVNVVK K HMM: 384-469 GMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK T ALI: 146-234 CVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRG ENV: 131-252 GDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGSTDHGLLF HIWP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVAKEINGF FLEDKTVENP TKKGEFKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYTD KNMSARRDGK KDPTGIGLYP EWAWAWPVNR RIIYNGASVD PSGKPWSAKK AVIKWVGDKW VGDVPDGVGD PGSGRPPFIM KPDGVASLFG PGLADGPFPE HYEPLECPVE KNFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNINGNILH EVGIPWHFGW ITTKDRQYNP GDKKAEVFTW GDAANLLVPT IGDANTTIPE SKAFMVNVVK K HMM: 634-698 GPFPE HYEPLECPVE KNFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH ALI: 396-458 MLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI ENV: 389-506 KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVAKEINGF FLEDKTVENP TKKGEFKE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVAKEINGF FLEDKTVENP TKKGEFKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYTD KNMSARRDGK KDPTGIGLYP EWAWAWPVNR RIIYNGASVD PSGKPWSAKK AVIKWVGDKW VGDVPDGVGD PGSGRPPFIM KPDGVASLFG PGLADGPFPE HYEPLECPVE KNFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNINGNILH EVGIPWHFGW ITTKDRQYNP GDKKAEVFTW GDAANLLVPT IGDANTTIPE SKAFMVNVVK K HMM: 874-911 ALI: 723-760 SKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PF ENV: 716-764 PEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNING Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVAKEINGF FLEDKTVENP TKKGEFKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYTD KNMSARRDGK KDPTGIGLYP EWAWAWPVNR RIIYNGASVD PSGKPWSAKK AVIKWVGDKW VGDVPDGVGD PGSGRPPFIM KPDGVASLFG PGLADGPFPE HYEPLECPVE KNFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNINGNILH EVGIPWHFGW ITTKDRQYNP GDKKAEVFTW GDAANLLVPT IGDANTTIPE SKAFMVNVVK K HMM: 226-464 GGG VAAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWN ALI: 9-232 NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAM ENV: 4-239 WIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV Q Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPIAF KWITAAMEKG AKVICVDPRF TQSAAKAHIY APLRSGTDIA FLGGMIRYII ENKLYFEEYV RNYTNATFLV NPEFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGRIKKD PTMQDPNCVF QLMKKHYSRY TPEVVNKITG TPVDKLIEIY KIYGSTGTPD RAGNELYAMG WTQHTVGTQN IRTMCIIQLL LGNMGIPGGG VAAMRGESNV QGSTDHGLLF HIWPGYLNTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNASLDE AYNLLPKIDD GANYSWLNLF DVMYKGKFTG FFAWGMNPAC SGAHSNKVRQ ALTRLDWMVN VNLYDNETGS FWRGPGMDPK KIRTEVFMLP CAASIEKEGS IINSGRWNQW RYKAIDPPGV ALPDGDICSE IYFKVKELYE KEGGPNMEAI TKLSWNYGTK TFDGHYHFDP HSVAKEINGF FLEDKTVENP TKKGEFKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYTD KNMSARRDGK KDPTGIGLYP EWAWAWPVNR RIIYNGASVD PSGKPWSAKK AVIKWVGDKW VGDVPDGVGD PGSGRPPFIM KPDGVASLFG PGLADGPFPE HYEPLECPVE KNFLSPQKSN PTIKRFDKPG VGSDVDVYSG IDSCDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNINGNILH EVGIPWHFGW ITTKDRQYNP GDKKAEVFTW GDAANLLVPT IGDANTTIPE SKAFMVNVVK K HMM: 849-894 ALI: 715-760 QPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PF ENV: 682-769 CDPKYPF ICATYRISEH WQTGLQTRWC PWLSEMQPEM WCEMSKELAK ERGISNGDKV IVSSPRGEVE CVAIVTPRFK PFNINGNILH E Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHYCDLK NADVILIMGS NAAEHHPIAF KWILRAKEKG ATIIHVDPRY TRTSARCDFH VPLRSGTDIA FLGGMINYIL EKDKYFKDYV LNYTNASFII GEDYSFNDGL FSGYDAQKRK YDKATWVLEK DGSGLPKRDM TLSNPRSVFQ MLKNHYSRYT LDKVSSITGV SKENLLKVYE IYSATGVPDK AGTECYALGW THHTVGSQNI RTMAIIQLLL GNMGIAGGGI NALRGEPNVQ GSTDHCILYG NLPGYLKMPS ASLESLDHYL EKYTPVSKDP QSANYYSNYP KFFVSFLKSL WDDKATKENG FGYNWMPKMD DGKHYSTMHM VDAMYEGKVK GYFCVAADTA VSTPNSNKVR KAMENLDWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PASATMEKEG SQSNSGRWVQ WKYKAADAPG DGIPVGEIEI KIMAAVKKLY EKEGGPNAEA ITNLKWDYLD SKGHMDVLKV SHQINGRFTE DTVIEDKAKG TKTEFKKGQL VPTFGNLQAD GKTACGNWIM SGSYTADGIN KMQSRGKEDP TGLGLFPNWS FAWPVNRRII YNRASCDVNG KPYNPKRKLL EWKGDKWVGD VPDGPWPPMA DKEKGKYPFI MKQDGVASLF GPGMVDGPFP EHYEPLESPL TKNPMSSQLI NPAIEIFKGE MDKVASASEK FPYVCTTYSC TEHWCTGALT RWQAWLLEMQ PELYVEISEQ LAKEKGIQNG ARVKVSSVRG EAPCVAMVTK RFKPFTVEGK TVHQVGMPFN YGWLFPEDGS GGDSTNMLTP TAGCANTFCP EYKAFMVNVE KA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
PF00384: 2-370 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
PF01568: 684-804 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
Sequence: MTNHYCDLK NADVILIMGS NAAEHHPIAF KWILRAKEKG ATIIHVDPRY TRTSARCDFH VPLRSGTDIA FLGGMINYIL EKDKYFKDYV LNYTNASFII GEDYSFNDGL FSGYDAQKRK YDKATWVLEK DGSGLPKRDM TLSNPRSVFQ MLKNHYSRYT LDKVSSITGV SKENLLKVYE IYSATGVPDK AGTECYALGW THHTVGSQNI RTMAIIQLLL GNMGIAGGGI NALRGEPNVQ GSTDHCILYG NLPGYLKMPS ASLESLDHYL EKYTPVSKDP QSANYYSNYP KFFVSFLKSL WDDKATKENG FGYNWMPKMD DGKHYSTMHM VDAMYEGKVK GYFCVAADTA VSTPNSNKVR KAMENLDWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PASATMEKEG SQSNSGRWVQ WKYKAADAPG DGIPVGEIEI KIMAAVKKLY EKEGGPNAEA ITNLKWDYLD SKGHMDVLKV SHQINGRFTE DTVIEDKAKG TKTEFKKGQL VPTFGNLQAD GKTACGNWIM SGSYTADGIN KMQSRGKEDP TGLGLFPNWS FAWPVNRRII YNRASCDVNG KPYNPKRKLL EWKGDKWVGD VPDGPWPPMA DKEKGKYPFI MKQDGVASLF GPGMVDGPFP EHYEPLESPL TKNPMSSQLI NPAIEIFKGE MDKVASASEK FPYVCTTYSC TEHWCTGALT RWQAWLLEMQ PELYVEISEQ LAKEKGIQNG ARVKVSSVRG EAPCVAMVTK RFKPFTVEGK TVHQVGMPFN YGWLFPEDGS GGDSTNMLTP TAGCANTFCP EYKAFMVNVE KA HMM: 244-339 CILYG NLPGYLKMPS ASLESLDHYL EKYTPVSKDP QSANYYSNYP KFFVSFLKSL WDDKATKENG FGYNWMPKMD DGKHYSTMHM VDAMYEGKVK G ALI: 8-103 K NADVILIMGS NAAEHHPIAF KWILRAKEKG ATIIHVDPRY TRTSARCDFH VPLRSGTDIA FLGGMINYIL EKDKYFKDYV LNYTNASFII GEDYS ENV: 3-239 HYCDLK NADVILIMGS NAAEHHPIAF KWILRAKEKG ATIIHVDPRY TRTSARCDFH VPLRSGTDIA FLGGMINYIL EKDKYFKDYV LNYTNASFII GEDYSFNDGL FSGYDAQKRK YDKATWVLEK DGSGLPKRDM TLSNPRSVFQ MLKNHYSRYT LDKVSSITGV SKENLLKVYE IYSATGVPDK AGTECYALGW THHTVGSQNI RTMAIIQLLL GNMGIAGGGI NALRGEPNVQ G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MTNHYCDLK NADVILIMGS NAAEHHPIAF KWILRAKEKG ATIIHVDPRY TRTSARCDFH VPLRSGTDIA FLGGMINYIL EKDKYFKDYV LNYTNASFII GEDYSFNDGL FSGYDAQKRK YDKATWVLEK DGSGLPKRDM TLSNPRSVFQ MLKNHYSRYT LDKVSSITGV SKENLLKVYE IYSATGVPDK AGTECYALGW THHTVGSQNI RTMAIIQLLL GNMGIAGGGI NALRGEPNVQ GSTDHCILYG NLPGYLKMPS ASLESLDHYL EKYTPVSKDP QSANYYSNYP KFFVSFLKSL WDDKATKENG FGYNWMPKMD DGKHYSTMHM VDAMYEGKVK GYFCVAADTA VSTPNSNKVR KAMENLDWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PASATMEKEG SQSNSGRWVQ WKYKAADAPG DGIPVGEIEI KIMAAVKKLY EKEGGPNAEA ITNLKWDYLD SKGHMDVLKV SHQINGRFTE DTVIEDKAKG TKTEFKKGQL VPTFGNLQAD GKTACGNWIM SGSYTADGIN KMQSRGKEDP TGLGLFPNWS FAWPVNRRII YNRASCDVNG KPYNPKRKLL EWKGDKWVGD VPDGPWPPMA DKEKGKYPFI MKQDGVASLF GPGMVDGPFP EHYEPLESPL TKNPMSSQLI NPAIEIFKGE MDKVASASEK FPYVCTTYSC TEHWCTGALT RWQAWLLEMQ PELYVEISEQ LAKEKGIQNG ARVKVSSVRG EAPCVAMVTK RFKPFTVEGK TVHQVGMPFN YGWLFPEDGS GGDSTNMLTP TAGCANTFCP EYKAFMVNVE KA HMM: 875-897 ALI: 714-736 EISEQ LAKEKGIQNG ARVKVSSV ENV: 706-749 EMQ PELYVEISEQ LAKEKGIQNG ARVKVSSVRG EAPCVAMVTK R Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MTNHYCDLK NADVILIMGS NAAEHHPIAF KWILRAKEKG ATIIHVDPRY TRTSARCDFH VPLRSGTDIA FLGGMINYIL EKDKYFKDYV LNYTNASFII GEDYSFNDGL FSGYDAQKRK YDKATWVLEK DGSGLPKRDM TLSNPRSVFQ MLKNHYSRYT LDKVSSITGV SKENLLKVYE IYSATGVPDK AGTECYALGW THHTVGSQNI RTMAIIQLLL GNMGIAGGGI NALRGEPNVQ GSTDHCILYG NLPGYLKMPS ASLESLDHYL EKYTPVSKDP QSANYYSNYP KFFVSFLKSL WDDKATKENG FGYNWMPKMD DGKHYSTMHM VDAMYEGKVK GYFCVAADTA VSTPNSNKVR KAMENLDWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PASATMEKEG SQSNSGRWVQ WKYKAADAPG DGIPVGEIEI KIMAAVKKLY EKEGGPNAEA ITNLKWDYLD SKGHMDVLKV SHQINGRFTE DTVIEDKAKG TKTEFKKGQL VPTFGNLQAD GKTACGNWIM SGSYTADGIN KMQSRGKEDP TGLGLFPNWS FAWPVNRRII YNRASCDVNG KPYNPKRKLL EWKGDKWVGD VPDGPWPPMA DKEKGKYPFI MKQDGVASLF GPGMVDGPFP EHYEPLESPL TKNPMSSQLI NPAIEIFKGE MDKVASASEK FPYVCTTYSC TEHWCTGALT RWQAWLLEMQ PELYVEISEQ LAKEKGIQNG ARVKVSSVRG EAPCVAMVTK RFKPFTVEGK TVHQVGMPFN YGWLFPEDGS GGDSTNMLTP TAGCANTFCP EYKAFMVNVE KA HMM: 230-466 ALRGEPNVQ GSTDHCILYG NLPGYLKMPS ASLESLDHYL EKYTPVSKDP QSANYYSNYP KFFVSFLKSL WDDKATKENG FGYNWMPKMD DGKHYSTMHM VDAMYEGKVK GYFCVAADTA VSTPNSNKVR KAMENLDWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PASATMEKEG SQSNSGRWVQ WKYKAADAPG DGIPVGEIEI KIMAAVKKLY EKEGGPNAEA ITNLKWDY ALI: 10-230 ADVILIMGS NAAEHHPIAF KWILRAKEKG ATIIHVDPRY TRTSARCDFH VPLRSGTDIA FLGGMINYIL EKDKYFKDYV LNYTNASFII GEDYSFNDGL FSGYDAQKRK YDKATWVLEK DGSGLPKRDM TLSNPRSVFQ MLKNHYSRYT LDKVSSITGV SKENLLKVYE IYSATGVPDK AGTECYALGW THHTVGSQNI RTMAIIQLLL GNMGIAGGGI NA ENV: 3-244 HYCDLK NADVILIMGS NAAEHHPIAF KWILRAKEKG ATIIHVDPRY TRTSARCDFH VPLRSGTDIA FLGGMINYIL EKDKYFKDYV LNYTNASFII GEDYSFNDGL FSGYDAQKRK YDKATWVLEK DGSGLPKRDM TLSNPRSVFQ MLKNHYSRYT LDKVSSITGV SKENLLKVYE IYSATGVPDK AGTECYALGW THHTVGSQNI RTMAIIQLLL GNMGIAGGGI NALRGEPNVQ GSTDHC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MTNHYCDLK NADVILIMGS NAAEHHPIAF KWILRAKEKG ATIIHVDPRY TRTSARCDFH VPLRSGTDIA FLGGMINYIL EKDKYFKDYV LNYTNASFII GEDYSFNDGL FSGYDAQKRK YDKATWVLEK DGSGLPKRDM TLSNPRSVFQ MLKNHYSRYT LDKVSSITGV SKENLLKVYE IYSATGVPDK AGTECYALGW THHTVGSQNI RTMAIIQLLL GNMGIAGGGI NALRGEPNVQ GSTDHCILYG NLPGYLKMPS ASLESLDHYL EKYTPVSKDP QSANYYSNYP KFFVSFLKSL WDDKATKENG FGYNWMPKMD DGKHYSTMHM VDAMYEGKVK GYFCVAADTA VSTPNSNKVR KAMENLDWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PASATMEKEG SQSNSGRWVQ WKYKAADAPG DGIPVGEIEI KIMAAVKKLY EKEGGPNAEA ITNLKWDYLD SKGHMDVLKV SHQINGRFTE DTVIEDKAKG TKTEFKKGQL VPTFGNLQAD GKTACGNWIM SGSYTADGIN KMQSRGKEDP TGLGLFPNWS FAWPVNRRII YNRASCDVNG KPYNPKRKLL EWKGDKWVGD VPDGPWPPMA DKEKGKYPFI MKQDGVASLF GPGMVDGPFP EHYEPLESPL TKNPMSSQLI NPAIEIFKGE MDKVASASEK FPYVCTTYSC TEHWCTGALT RWQAWLLEMQ PELYVEISEQ LAKEKGIQNG ARVKVSSVRG EAPCVAMVTK RFKPFTVEGK TVHQVGMPFN YGWLFPEDGS GGDSTNMLTP TAGCANTFCP EYKAFMVNVE KA HMM: 227-465 GI NALRGEPNVQ GSTDHCILYG NLPGYLKMPS ASLESLDHYL EKYTPVSKDP QSANYYSNYP KFFVSFLKSL WDDKATKENG FGYNWMPKMD DGKHYSTMHM VDAMYEGKVK GYFCVAADTA VSTPNSNKVR KAMENLDWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PASATMEKEG SQSNSGRWVQ WKYKAADAPG DGIPVGEIEI KIMAAVKKLY EKEGGPNAEA ITNLKWD ALI: 10-232 ADVILIMGS NAAEHHPIAF KWILRAKEKG ATIIHVDPRY TRTSARCDFH VPLRSGTDIA FLGGMINYIL EKDKYFKDYV LNYTNASFII GEDYSFNDGL FSGYDAQKRK YDKATWVLEK DGSGLPKRDM TLSNPRSVFQ MLKNHYSRYT LDKVSSITGV SKENLLKVYE IYSATGVPDK AGTECYALGW THHTVGSQNI RTMAIIQLLL GNMGIAGGGI NALR ENV: 3-238 HYCDLK NADVILIMGS NAAEHHPIAF KWILRAKEKG ATIIHVDPRY TRTSARCDFH VPLRSGTDIA FLGGMINYIL EKDKYFKDYV LNYTNASFII GEDYSFNDGL FSGYDAQKRK YDKATWVLEK DGSGLPKRDM TLSNPRSVFQ MLKNHYSRYT LDKVSSITGV SKENLLKVYE IYSATGVPDK AGTECYALGW THHTVGSQNI RTMAIIQLLL GNMGIAGGGI NALRGEPNVQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MVDVNRRGF LKISGAVLAA SGLGISLKPV SAYAQPLKIQ YAKETTTICP YCSVGCSIIV STRKGKVVNT EGDPDSPINR GSLCTKGGSI YQMANNENRL GKPLYRAPYA TEWKEVDWEW ALERIAKNVK TSRDKSFRAA NDKGELVNRT EGIASVGSAA IDNEECFVYQ KFLRGLGLVY IEHQARI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180
PF04879: 41-95 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
Sequence: MVDVNRRGF LKISGAVLAA SGLGISLKPV SAYAQPLKIQ YAKETTTICP YCSVGCSIIV STRKGKVVNT EGDPDSPINR GSLCTKGGSI YQMANNENRL GKPLYRAPYA TEWKEVDWEW ALERIAKNVK TSRDKSFRAA NDKGELVNRT EGIASVGSAA IDNEECFVYQ KFLRGLGLVY IEHQARI HMM: 18-62 A SGLGISLKPV SAYAQPLKIQ YAKETTTICP YCSVGCSIIV STRK ALI: 2-50 DVNRRGF LKISGAVLAA SGLGISLKPV SAYAQPLKIQ YAKETTTICP YC ENV: 1-57 VDVNRRGF LKISGAVLAA SGLGISLKPV SAYAQPLKIQ YAKETTTICP YCSVGCSII Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180
Sequence: MVDVNRRGF LKISGAVLAA SGLGISLKPV SAYAQPLKIQ YAKETTTICP YCSVGCSIIV STRKGKVVNT EGDPDSPINR GSLCTKGGSI YQMANNENRL GKPLYRAPYA TEWKEVDWEW ALERIAKNVK TSRDKSFRAA NDKGELVNRT EGIASVGSAA IDNEECFVYQ KFLRGLGLVY IEHQARI HMM: 126-175 NVK TSRDKSFRAA NDKGELVNRT EGIASVGSAA IDNEECFVYQ KFLRGLG ALI: 82-129 CTKGGSI YQMANNENRL GKPLYRAPYA TEWKEVDWEW ALERIAKNVK T ENV: 55-139 SIIV STRKGKVVNT EGDPDSPINR GSLCTKGGSI YQMANNENRL GKPLYRAPYA TEWKEVDWEW ALERIAKNVK TSRDKSFRAA N Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180
Sequence: MVDVNRRGF LKISGAVLAA SGLGISLKPV SAYAQPLKIQ YAKETTTICP YCSVGCSIIV STRKGKVVNT EGDPDSPINR GSLCTKGGSI YQMANNENRL GKPLYRAPYA TEWKEVDWEW ALERIAKNVK TSRDKSFRAA NDKGELVNRT EGIASVGSAA IDNEECFVYQ KFLRGLGLVY IEHQARI HMM: 100-159 KPLYRAPYA TEWKEVDWEW ALERIAKNVK TSRDKSFRAA NDKGELVNRT EGIASVGSAA I ALI: 72-129 PDSPINR GSLCTKGGSI YQMANNENRL GKPLYRAPYA TEWKEVDWEW ALERIAKNVK T ENV: 1-139 VDVNRRGF LKISGAVLAA SGLGISLKPV SAYAQPLKIQ YAKETTTICP YCSVGCSIIV STRKGKVVNT EGDPDSPINR GSLCTKGGSI YQMANNENRL GKPLYRAPYA TEWKEVDWEW ALERIAKNVK TSRDKSFRAA N Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180
Sequence: MKITINGIT CDADAGQTVL QAARANGIYI PSLCYHDKTG VAGKCRVCVA EVEDMRGLQA TCTLPVREGM KIDTQSEKAL AAQRLVVDLL LSTGRHDCIS CEKNGICELQ DAAYYLGIER PSIQYADVQK GIDESSAFIR VDRNKCISCG RCVAGCNDVV VNEVLDFGRR GHETSIIFDT DSPMGASTCV QCGECVQLCP VGALIEKKSI GKARSWEIEK VRTTCPYCGV GCQLYLHTKG EQIVKVTGVE EGAPNKGRLC VKGRFGYDFI YSGERLTTPL IKENGAFREA SWDEALDLVA GKFKQIIAEN GPDAIAGVSC ARSINEDSYQ MQKLFRAVIG TNNIDHCART
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
PF13510: 1-75 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
PF10588: 82-119 ◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
PF12838: 143-202 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF04879: 217-271 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF00384: 273-348 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MKITINGIT CDADAGQTVL QAARANGIYI PSLCYHDKTG VAGKCRVCVA EVEDMRGLQA TCTLPVREGM KIDTQSEKAL AAQRLVVDLL LSTGRHDCIS CEKNGICELQ DAAYYLGIER PSIQYADVQK GIDESSAFIR VDRNKCISCG RCVAGCNDVV VNEVLDFGRR GHETSIIFDT DSPMGASTCV QCGECVQLCP VGALIEKKSI GKARSWEIEK VRTTCPYCGV GCQLYLHTKG EQIVKVTGVE EGAPNKGRLC VKGRFGYDFI YSGERLTTPL IKENGAFREA SWDEALDLVA GKFKQIIAEN GPDAIAGVSC ARSINEDSYQ MQKLFRAVIG TNNIDHCART HMM: 127-219 QK GIDESSAFIR VDRNKCISCG RCVAGCNDVV VNEVLDFGRR GHETSIIFDT DSPMGASTCV QCGECVQLCP VGALIEKKSI GKARSWEIEK V ALI: 259-343 VKGRFGYDFI YSGERLTTPL IKENGAFREA SWDEALDLVA GKFKQIIAEN GPDAIAGVSC ARSINEDSYQ MQKLFRAVIG TNNID ENV: 238-346 G EQIVKVTGVE EGAPNKGRLC VKGRFGYDFI YSGERLTTPL IKENGAFREA SWDEALDLVA GKFKQIIAEN GPDAIAGVSC ARSINEDSYQ MQKLFRAVIG TNNIDHCA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
Sequence: MKITINGIT CDADAGQTVL QAARANGIYI PSLCYHDKTG VAGKCRVCVA EVEDMRGLQA TCTLPVREGM KIDTQSEKAL AAQRLVVDLL LSTGRHDCIS CEKNGICELQ DAAYYLGIER PSIQYADVQK GIDESSAFIR VDRNKCISCG RCVAGCNDVV VNEVLDFGRR GHETSIIFDT DSPMGASTCV QCGECVQLCP VGALIEKKSI GKARSWEIEK VRTTCPYCGV GCQLYLHTKG EQIVKVTGVE EGAPNKGRLC VKGRFGYDFI YSGERLTTPL IKENGAFREA SWDEALDLVA GKFKQIIAEN GPDAIAGVSC ARSINEDSYQ MQKLFRAVIG TNNIDHCART HMM: 89-171 LSTGRHDCIS CEKNGICELQ DAAYYLGIER PSIQYADVQK GIDESSAFIR VDRNKCISCG RCVAGCNDVV VNEVLDFGRR GHE ALI: 238-315 G EQIVKVTGVE EGAPNKGRLC VKGRFGYDFI YSGERLTTPL IKENGAFREA SWDEALDLVA GKFKQIIAEN GPDAIAG ENV: 214-347 WEIEK VRTTCPYCGV GCQLYLHTKG EQIVKVTGVE EGAPNKGRLC VKGRFGYDFI YSGERLTTPL IKENGAFREA SWDEALDLVA GKFKQIIAEN GPDAIAGVSC ARSINEDSYQ MQKLFRAVIG TNNIDHCAR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340
Sequence: MNADSKAEE DRHVDPVCSM VVSSDSEYYY DYKEKHYYFC SEHCLRKFKE HPEQYLNKEI SPSPEKYNKL ITCTCPMHPE IKQQGPGNCP KCGMALEPVE VQAAATKTVY TCPMHPEVVQ DHPGNCPKCG MALEPVKFRV EEKNEELIYM SRRFWVCTIL ALPVFFLAMV ADMMPAWLPN WLSMQAVQWI EFALASPVVL WGGWPFFVRG WQSVQTWNLN MFTLIALGVS VAWIYSVVAL LFPQIFPLIM QMESGLVPVY FEAAAVITTL VLLGQVLELR ARSRTNAAIQ MLLGLAPNTA RIVRNDGTEE DVPLEHVQPG DTLRVRPGEK IPVDGTVIDG ESNVDESMVT GEPIPVAKLA GEKLIGATVN GTGSLLMRAE KVGSDTLLAQ IVDMVAEAQR SRAPIQKLAD IVAGYFVPAV VGVAVVAFIA WWVWGPEPRL AHSIVNAVAV LIIACPCALG LATPISIMVG TGRGALAGVL IKNAEALEIM EKVDTLVVDK TGTLTEGKPK LVLVQAEAGF NEDEILRMAA SLERASEHSL AEAIVHGAEE RGVTLVKANN FQSITGKGVT GEVDGHTVVA GNAKLLESSG IRAGDLLHQA DRQRVEGNTV MLIAINGKAA GLIGVADPIK DSTTEAIRDL HADGIKIVML TGDSLTTAKA VAGKLGIDQV HAEVLPEQKA ELIKELQADG CIVAMAGDGI NDAPALAQAQ VGIAMGTGTD VAIESAGITL IKGDLRGIVR ARRLSRATMR NIRQNLFFAF IYNTIGIPIA AGVLYPFFGI LLSPMIAAAA MSFSSVSVIG NALRLRGAKL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
PF04945: 11-57 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF19335: 107-135 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00122: 293-474 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF00702: 491-708 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
Sequence: MNADSKAEE DRHVDPVCSM VVSSDSEYYY DYKEKHYYFC SEHCLRKFKE HPEQYLNKEI SPSPEKYNKL ITCTCPMHPE IKQQGPGNCP KCGMALEPVE VQAAATKTVY TCPMHPEVVQ DHPGNCPKCG MALEPVKFRV EEKNEELIYM SRRFWVCTIL ALPVFFLAMV ADMMPAWLPN WLSMQAVQWI EFALASPVVL WGGWPFFVRG WQSVQTWNLN MFTLIALGVS VAWIYSVVAL LFPQIFPLIM QMESGLVPVY FEAAAVITTL VLLGQVLELR ARSRTNAAIQ MLLGLAPNTA RIVRNDGTEE DVPLEHVQPG DTLRVRPGEK IPVDGTVIDG ESNVDESMVT GEPIPVAKLA GEKLIGATVN GTGSLLMRAE KVGSDTLLAQ IVDMVAEAQR SRAPIQKLAD IVAGYFVPAV VGVAVVAFIA WWVWGPEPRL AHSIVNAVAV LIIACPCALG LATPISIMVG TGRGALAGVL IKNAEALEIM EKVDTLVVDK TGTLTEGKPK LVLVQAEAGF NEDEILRMAA SLERASEHSL AEAIVHGAEE RGVTLVKANN FQSITGKGVT GEVDGHTVVA GNAKLLESSG IRAGDLLHQA DRQRVEGNTV MLIAINGKAA GLIGVADPIK DSTTEAIRDL HADGIKIVML TGDSLTTAKA VAGKLGIDQV HAEVLPEQKA ELIKELQADG CIVAMAGDGI NDAPALAQAQ VGIAMGTGTD VAIESAGITL IKGDLRGIVR ARRLSRATMR NIRQNLFFAF IYNTIGIPIA AGVLYPFFGI LLSPMIAAAA MSFSSVSVIG NALRLRGAKL HMM: 416-446 PAV VGVAVVAFIA WWVWGPEPRL AHSIVNAV ALI: 26-56 YYY DYKEKHYYFC SEHCLRKFKE HPEQYLNK ENV: 17-60 SM VVSSDSEYYY DYKEKHYYFC SEHCLRKFKE HPEQYLNKEI SP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MNADSKAEE DRHVDPVCSM VVSSDSEYYY DYKEKHYYFC SEHCLRKFKE HPEQYLNKEI SPSPEKYNKL ITCTCPMHPE IKQQGPGNCP KCGMALEPVE VQAAATKTVY TCPMHPEVVQ DHPGNCPKCG MALEPVKFRV EEKNEELIYM SRRFWVCTIL ALPVFFLAMV ADMMPAWLPN WLSMQAVQWI EFALASPVVL WGGWPFFVRG WQSVQTWNLN MFTLIALGVS VAWIYSVVAL LFPQIFPLIM QMESGLVPVY FEAAAVITTL VLLGQVLELR ARSRTNAAIQ MLLGLAPNTA RIVRNDGTEE DVPLEHVQPG DTLRVRPGEK IPVDGTVIDG ESNVDESMVT GEPIPVAKLA GEKLIGATVN GTGSLLMRAE KVGSDTLLAQ IVDMVAEAQR SRAPIQKLAD IVAGYFVPAV VGVAVVAFIA WWVWGPEPRL AHSIVNAVAV LIIACPCALG LATPISIMVG TGRGALAGVL IKNAEALEIM EKVDTLVVDK TGTLTEGKPK LVLVQAEAGF NEDEILRMAA SLERASEHSL AEAIVHGAEE RGVTLVKANN FQSITGKGVT GEVDGHTVVA GNAKLLESSG IRAGDLLHQA DRQRVEGNTV MLIAINGKAA GLIGVADPIK DSTTEAIRDL HADGIKIVML TGDSLTTAKA VAGKLGIDQV HAEVLPEQKA ELIKELQADG CIVAMAGDGI NDAPALAQAQ VGIAMGTGTD VAIESAGITL IKGDLRGIVR ARRLSRATMR NIRQNLFFAF IYNTIGIPIA AGVLYPFFGI LLSPMIAAAA MSFSSVSVIG NALRLRGAKL HMM: 425-452 AFIA WWVWGPEPRL AHSIVNAVAV LIIA ALI: 30-57 YKEKHYYFC SEHCLRKFKE HPEQYLNKE ENV: 21-74 SSDSEYYY DYKEKHYYFC SEHCLRKFKE HPEQYLNKEI SPSPEKYNKL ITCTCP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800
Sequence: MSLLKIWSE AGQTMMKTEK RQKGFTLIEM MIALTVLALV VAAVSHALAQ SLAMAHRIKK DTTLSLLAQS KMAEIEAAKE GAASDHGNFG GNFSQYGWQV SVRGSGISTL KKVEVTVLDT LSEKRESFRL TSLQYREESP
10 20 30 40 50 60 70 80 90 100 110 120 130
PF07963: 18-43 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
Sequence: MSLLKIWSE AGQTMMKTEK RQKGFTLIEM MIALTVLALV VAAVSHALAQ SLAMAHRIKK DTTLSLLAQS KMAEIEAAKE GAASDHGNFG GNFSQYGWQV SVRGSGISTL KKVEVTVLDT LSEKRESFRL TSLQYREESP HMM: 212-262 ALI: 24-76 TLIEM MIALTVLALV VAAVSHALAQ SLAMAHRIKK DTTLSLLAQS KMAEIEAA ENV: 5-83 IWSE AGQTMMKTEK RQKGFTLIEM MIALTVLALV VAAVSHALAQ SLAMAHRIKK DTTLSLLAQS KMAEIEAAKE GAASD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130
Sequence: MQQIKLSID GKEVTGTAGQ TILEIALASG IDIPTLCYHP KISKTGACRL CLVRVNNGML KTSCTEPAME GMSIITEDEE IRGIRKGILE LLLSEGDHNC LYCDANGACE LQTLVNRYGI EPVSSDFPRN VRVIDYESSE GLKRNENRCV LCGRCVKACG EIQMSNVWQF TDRGSHAHLT SGMFQTIGDS SCVKCGTCVQ LCPTGALTFQ TVLGRGQNWE LEKESSICIY CGVGCKIDFC KNKAGQLVKA LGHDDGPNNG HLCVKGRFGF DFVQSPKRLS KPLIRKNGQL EEASWDEALD LVASRFKEIK EKSGPDALAA LSSAKCTNED NYLMQKFMRA AIGTNNVDHC ARL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 1-76 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌
PF10588: 83-120 ◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌
PF12838: 146-205 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF04879: 224-273 ♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
PF00384: 276-352 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MQQIKLSID GKEVTGTAGQ TILEIALASG IDIPTLCYHP KISKTGACRL CLVRVNNGML KTSCTEPAME GMSIITEDEE IRGIRKGILE LLLSEGDHNC LYCDANGACE LQTLVNRYGI EPVSSDFPRN VRVIDYESSE GLKRNENRCV LCGRCVKACG EIQMSNVWQF TDRGSHAHLT SGMFQTIGDS SCVKCGTCVQ LCPTGALTFQ TVLGRGQNWE LEKESSICIY CGVGCKIDFC KNKAGQLVKA LGHDDGPNNG HLCVKGRFGF DFVQSPKRLS KPLIRKNGQL EEASWDEALD LVASRFKEIK EKSGPDALAA LSSAKCTNED NYLMQKFMRA AIGTNNVDHC ARL HMM: 107-171 CE LQTLVNRYGI EPVSSDFPRN VRVIDYESSE GLKRNENRCV LCGRCVKACG EIQMSNVWQF TDR ALI: 258-318 G HLCVKGRFGF DFVQSPKRLS KPLIRKNGQL EEASWDEALD LVASRFKEIK EKSGPDALAA ENV: 232-350 GCKIDFC KNKAGQLVKA LGHDDGPNNG HLCVKGRFGF DFVQSPKRLS KPLIRKNGQL EEASWDEALD LVASRFKEIK EKSGPDALAA LSSAKCTNED NYLMQKFMRA AIGTNNVDHC AR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MNSAAFFKM SYGVYIVSSR KDGQFNGQVA NSVFQATSDP PTVVASINKN NLTHEFIQAS RKFTVSVLAK AAPMNLIGLF GFKSGRTVNK FADVSFKMGV LEVPIVLDHT VAYMEAEVID EKDCGTHTLF IGKIVDCEIV SDEEPMTYAY YHEVKGGKSP KNAPTYREEK KEPTAAPQTG GKMEKYTCTI CGYVYDPEQG DPESGIAPGT AFEDLPDDWT CPICGADKSQ FEKGG
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230
PF01613: 8-148 ✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF00301: 183-230 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦
Sequence: MNSAAFFKM SYGVYIVSSR KDGQFNGQVA NSVFQATSDP PTVVASINKN NLTHEFIQAS RKFTVSVLAK AAPMNLIGLF GFKSGRTVNK FADVSFKMGV LEVPIVLDHT VAYMEAEVID EKDCGTHTLF IGKIVDCEIV SDEEPMTYAY YHEVKGGKSP KNAPTYREEK KEPTAAPQTG GKMEKYTCTI CGYVYDPEQG DPESGIAPGT AFEDLPDDWT CPICGADKSQ FEKGG HMM: 408-468 ALI: 167-227 EK KEPTAAPQTG GKMEKYTCTI CGYVYDPEQG DPESGIAPGT AFEDLPDDWT CPICGADKS ENV: 117-232 ID EKDCGTHTLF IGKIVDCEIV SDEEPMTYAY YHEVKGGKSP KNAPTYREEK KEPTAAPQTG GKMEKYTCTI CGYVYDPEQG DPESGIAPGT AFEDLPDDWT CPICGADKSQ FEKG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230
No PFAM domains
Sequence: MEKANSNFG DVMVVGGGIS GIQASLDLAT AGFKVYLVEK SPSIGGHMAQ LDKTFPTNDC SM HMM: 4-45 NSNFG DVMVVGGGIS GIQASLDLAT AGFKVYLVEK SPSIGGH ALI: 7-46 FG DVMVVGGGIS GIQASLDLAT AGFKVYLVEK SPSIGGHM ENV: 4-56 NSNFG DVMVVGGGIS GIQASLDLAT AGFKVYLVEK SPSIGGHMAQ LDKTFPTN Position: 10 20 30 40 50 60
Sequence: MEKANSNFG DVMVVGGGIS GIQASLDLAT AGFKVYLVEK SPSIGGHMAQ LDKTFPTNDC SM
10 20 30 40 50 60
PF12831: 9-48 ♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
Sequence: MEKANSNFG DVMVVGGGIS GIQASLDLAT AGFKVYLVEK SPSIGGHMAQ LDKTFPTNDC SM HMM: 4-45 NSNFG DVMVVGGGIS GIQASLDLAT AGFKVYLVEK SPSIGGH ALI: 7-46 FG DVMVVGGGIS GIQASLDLAT AGFKVYLVEK SPSIGGHM ENV: 4-56 NSNFG DVMVVGGGIS GIQASLDLAT AGFKVYLVEK SPSIGGHMAQ LDKTFPTN Position: 10 20 30 40 50 60
Sequence: MEGNESLKL VYDIIVVGGG PAGLTAGLYA ARGGLKALLL EGESSVSQIT VTDLVENYPG FPEGINGYDL VERFRTQAGR FGLKILTEDI RAIDAGAAEH WIVSGRDSAY EALSVILATG ANWRHLGVPG EAAFTGKGVS YCATCDGPFY RDREVVVVGG GDTAVQEALF LTRFARKVTI VHRRDRLRAT PILQERAFAH ERIDFAWDSV VEEIQGGEFV EGVRIRNLKN PEKSRIIPAD GAFIFVGLTP NTGFVRGLVN CDENGYILAD AEMKTSVKGI FACGDCISKL LRQVVTACGD AATAAFSAQL HVEALKGEDY GGRKA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
PF07992: 10-298 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MEGNESLKL VYDIIVVGGG PAGLTAGLYA ARGGLKALLL EGESSVSQIT VTDLVENYPG FPEGINGYDL VERFRTQAGR FGLKILTEDI RAIDAGAAEH WIVSGRDSAY EALSVILATG ANWRHLGVPG EAAFTGKGVS YCATCDGPFY RDREVVVVGG GDTAVQEALF LTRFARKVTI VHRRDRLRAT PILQERAFAH ERIDFAWDSV VEEIQGGEFV EGVRIRNLKN PEKSRIIPAD GAFIFVGLTP NTGFVRGLVN CDENGYILAD AEMKTSVKGI FACGDCISKL LRQVVTACGD AATAAFSAQL HVEALKGEDY GGRKA HMM: 153-211 VVVVGG GDTAVQEALF LTRFARKVTI VHRRDRLRAT PILQERAFAH ERIDFAWDSV VEE ALI: 126-184 VPG EAAFTGKGVS YCATCDGPFY RDREVVVVGG GDTAVQEALF LTRFARKVTI VHRRDR ENV: 69-196 VERFRTQAGR FGLKILTEDI RAIDAGAAEH WIVSGRDSAY EALSVILATG ANWRHLGVPG EAAFTGKGVS YCATCDGPFY RDREVVVVGG GDTAVQEALF LTRFARKVTI VHRRDRLRAT PILQERAF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
Sequence: MTNFYDVII IGAGVVGNAI ARELSRFDIK AAVIERELDV GGGTSSRNSG VVHSGIHYKP GTLRAKLNVQ GNAMMGNLCK ELKVKIEYLG KLTVAQDETD VETLHSLKAQ GDANGVPGLA ILNKQQMEKL QPGIGGIMAL HSPSTGIICP YGLTIALAEN ACANGVHFYL GQEVTAISRT EKGFEVKTTS GERFESRVLI NSAGLYSDAI CRMLGIDEYR IYPCRGEYLI LDKRLAGTLS LLVYPAPHKG GAGLGIHLTN TVDGNILIGP SNEYVDEADD YACTAEILSL LKKEGHDLLP GISAADFIRN FSGLRAKQAP PSEGGFRDFV IESRKDIPGF INLVGIESPG LTSAPAIGLM VRDMVEELLP LPFKASFIAE REGRAGFFYE LSPEERADLV AENPDYGEVV CRCEQITRKE VLDAIQNPLG VKTINGIKYR SRAMMGRCQG GFCLPRIVQI LEKEFGYKPE DYLLQHAHSP LFAGRVR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
PF01266: 5-362 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF04324: 407-461 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MTNFYDVII IGAGVVGNAI ARELSRFDIK AAVIERELDV GGGTSSRNSG VVHSGIHYKP GTLRAKLNVQ GNAMMGNLCK ELKVKIEYLG KLTVAQDETD VETLHSLKAQ GDANGVPGLA ILNKQQMEKL QPGIGGIMAL HSPSTGIICP YGLTIALAEN ACANGVHFYL GQEVTAISRT EKGFEVKTTS GERFESRVLI NSAGLYSDAI CRMLGIDEYR IYPCRGEYLI LDKRLAGTLS LLVYPAPHKG GAGLGIHLTN TVDGNILIGP SNEYVDEADD YACTAEILSL LKKEGHDLLP GISAADFIRN FSGLRAKQAP PSEGGFRDFV IESRKDIPGF INLVGIESPG LTSAPAIGLM VRDMVEELLP LPFKASFIAE REGRAGFFYE LSPEERADLV AENPDYGEVV CRCEQITRKE VLDAIQNPLG VKTINGIKYR SRAMMGRCQG GFCLPRIVQI LEKEFGYKPE DYLLQHAHSP LFAGRVR HMM: 4-45 YDVII IGAGVVGNAI ARELSRFDIK AAVIERELDV GGGTSSR ALI: 3-42 FYDVII IGAGVVGNAI ARELSRFDIK AAVIERELDV GGGT ENV: 1-53 TNFYDVII IGAGVVGNAI ARELSRFDIK AAVIERELDV GGGTSSRNSG VVHSG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MTNFYDVII IGAGVVGNAI ARELSRFDIK AAVIERELDV GGGTSSRNSG VVHSGIHYKP GTLRAKLNVQ GNAMMGNLCK ELKVKIEYLG KLTVAQDETD VETLHSLKAQ GDANGVPGLA ILNKQQMEKL QPGIGGIMAL HSPSTGIICP YGLTIALAEN ACANGVHFYL GQEVTAISRT EKGFEVKTTS GERFESRVLI NSAGLYSDAI CRMLGIDEYR IYPCRGEYLI LDKRLAGTLS LLVYPAPHKG GAGLGIHLTN TVDGNILIGP SNEYVDEADD YACTAEILSL LKKEGHDLLP GISAADFIRN FSGLRAKQAP PSEGGFRDFV IESRKDIPGF INLVGIESPG LTSAPAIGLM VRDMVEELLP LPFKASFIAE REGRAGFFYE LSPEERADLV AENPDYGEVV CRCEQITRKE VLDAIQNPLG VKTINGIKYR SRAMMGRCQG GFCLPRIVQI LEKEFGYKPE DYLLQHAHSP LFAGRVR HMM: 322-345 GGFRDFV IESRKDIPGF INLVGIE ALI: 179-204 EKGFEVKTTS GERFESRVLI NSAGLY ENV: 174-216 AISRT EKGFEVKTTS GERFESRVLI NSAGLYSDAI CRMLGIDE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480
Sequence: MTNHYTDMR NSDCILIMGS NAAEHHPMAF RWMLKAKERG ATLIHVDPRY TRTSARCDYH VPLRSGTDIA FLGGMINYIL SNDKWFKEYV LYYTNASFIV GKDYTFNDGL FSGYDAEKRK YNKDTWVLEK DDAGIPKRDM TLTDPRCVFQ MMKAHYSRYS MDKVSSVTGV SKENLLKVYQ AYSATGVPDK AGTECYALGW THHTVGSQNI RTMSIIQLLL GNMGIAGGGI NAMRGEPNVQ GSTDQAVLYN ILPGYLKMPS ASIDTIDHYL EKYTPVSKDP QSANYYQNYP KFFISFLKAL FDDKATKENG FGYNWLPKLD DGKHYSTMHL FDAMYAGKVK GYFCVGADTA VSTPNTTKVR KAMENLEWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PAAATMEKEG SQSNSGRMIQ WKYKAAEAPG DGLPVGEIEI KIMKAVKELY VKEGGPNAEP IVNLYWDYLD GKGHFDALKV CKRLNGFFLQ DTVIEDKAKG TKTEYKKGQL VPGFGNLQDD GSTASGNWVH CGSFGADGEN KMAKRGKEDP TGLGIYPNWA YVWPVNRRIM YNRASCDPTG KPWDPKRKVL EWVGDKWVGD VPDGPWPPLA DKENGKLPFI MKTDGVGAIF GPGMVDGPFP EHYEPLEGPL DKNPLNGQLF NPAAEIFKSD LDKVERASKK FPYVCTTYSC TEHWCTGALT RWQAWLLEAM PAAYMEIGDA LAKEKGITNG ERIRVSSVRG SVTCVAMVTK RFKPFTIEGK TVHQVGMPFN YGWLFPKGTK DDSTNFLTPT VGDANTFCPE YKAFMVNVEK L
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
PF00384: 1-369 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
PF01568: 684-803 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
Sequence: MTNHYTDMR NSDCILIMGS NAAEHHPMAF RWMLKAKERG ATLIHVDPRY TRTSARCDYH VPLRSGTDIA FLGGMINYIL SNDKWFKEYV LYYTNASFIV GKDYTFNDGL FSGYDAEKRK YNKDTWVLEK DDAGIPKRDM TLTDPRCVFQ MMKAHYSRYS MDKVSSVTGV SKENLLKVYQ AYSATGVPDK AGTECYALGW THHTVGSQNI RTMSIIQLLL GNMGIAGGGI NAMRGEPNVQ GSTDQAVLYN ILPGYLKMPS ASIDTIDHYL EKYTPVSKDP QSANYYQNYP KFFISFLKAL FDDKATKENG FGYNWLPKLD DGKHYSTMHL FDAMYAGKVK GYFCVGADTA VSTPNTTKVR KAMENLEWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PAAATMEKEG SQSNSGRMIQ WKYKAAEAPG DGLPVGEIEI KIMKAVKELY VKEGGPNAEP IVNLYWDYLD GKGHFDALKV CKRLNGFFLQ DTVIEDKAKG TKTEYKKGQL VPGFGNLQDD GSTASGNWVH CGSFGADGEN KMAKRGKEDP TGLGIYPNWA YVWPVNRRIM YNRASCDPTG KPWDPKRKVL EWVGDKWVGD VPDGPWPPLA DKENGKLPFI MKTDGVGAIF GPGMVDGPFP EHYEPLEGPL DKNPLNGQLF NPAAEIFKSD LDKVERASKK FPYVCTTYSC TEHWCTGALT RWQAWLLEAM PAAYMEIGDA LAKEKGITNG ERIRVSSVRG SVTCVAMVTK RFKPFTIEGK TVHQVGMPFN YGWLFPKGTK DDSTNFLTPT VGDANTFCPE YKAFMVNVEK L HMM: 224-465 AGGGI NAMRGEPNVQ GSTDQAVLYN ILPGYLKMPS ASIDTIDHYL EKYTPVSKDP QSANYYQNYP KFFISFLKAL FDDKATKENG FGYNWLPKLD DGKHYSTMHL FDAMYAGKVK GYFCVGADTA VSTPNTTKVR KAMENLEWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PAAATMEKEG SQSNSGRMIQ WKYKAAEAPG DGLPVGEIEI KIMKAVKELY VKEGGPNAEP IVNLYWD ALI: 7-232 MR NSDCILIMGS NAAEHHPMAF RWMLKAKERG ATLIHVDPRY TRTSARCDYH VPLRSGTDIA FLGGMINYIL SNDKWFKEYV LYYTNASFIV GKDYTFNDGL FSGYDAEKRK YNKDTWVLEK DDAGIPKRDM TLTDPRCVFQ MMKAHYSRYS MDKVSSVTGV SKENLLKVYQ AYSATGVPDK AGTECYALGW THHTVGSQNI RTMSIIQLLL GNMGIAGGGI NAMR ENV: 2-237 NHYTDMR NSDCILIMGS NAAEHHPMAF RWMLKAKERG ATLIHVDPRY TRTSARCDYH VPLRSGTDIA FLGGMINYIL SNDKWFKEYV LYYTNASFIV GKDYTFNDGL FSGYDAEKRK YNKDTWVLEK DDAGIPKRDM TLTDPRCVFQ MMKAHYSRYS MDKVSSVTGV SKENLLKVYQ AYSATGVPDK AGTECYALGW THHTVGSQNI RTMSIIQLLL GNMGIAGGGI NAMRGEPNV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MTNHYTDMR NSDCILIMGS NAAEHHPMAF RWMLKAKERG ATLIHVDPRY TRTSARCDYH VPLRSGTDIA FLGGMINYIL SNDKWFKEYV LYYTNASFIV GKDYTFNDGL FSGYDAEKRK YNKDTWVLEK DDAGIPKRDM TLTDPRCVFQ MMKAHYSRYS MDKVSSVTGV SKENLLKVYQ AYSATGVPDK AGTECYALGW THHTVGSQNI RTMSIIQLLL GNMGIAGGGI NAMRGEPNVQ GSTDQAVLYN ILPGYLKMPS ASIDTIDHYL EKYTPVSKDP QSANYYQNYP KFFISFLKAL FDDKATKENG FGYNWLPKLD DGKHYSTMHL FDAMYAGKVK GYFCVGADTA VSTPNTTKVR KAMENLEWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PAAATMEKEG SQSNSGRMIQ WKYKAAEAPG DGLPVGEIEI KIMKAVKELY VKEGGPNAEP IVNLYWDYLD GKGHFDALKV CKRLNGFFLQ DTVIEDKAKG TKTEYKKGQL VPGFGNLQDD GSTASGNWVH CGSFGADGEN KMAKRGKEDP TGLGIYPNWA YVWPVNRRIM YNRASCDPTG KPWDPKRKVL EWVGDKWVGD VPDGPWPPLA DKENGKLPFI MKTDGVGAIF GPGMVDGPFP EHYEPLEGPL DKNPLNGQLF NPAAEIFKSD LDKVERASKK FPYVCTTYSC TEHWCTGALT RWQAWLLEAM PAAYMEIGDA LAKEKGITNG ERIRVSSVRG SVTCVAMVTK RFKPFTIEGK TVHQVGMPFN YGWLFPKGTK DDSTNFLTPT VGDANTFCPE YKAFMVNVEK L HMM: 844-894 ALI: 704-753 LLEAM PAAYMEIGDA LAKEKGITNG ERIRVSSVRG SVTCVAMVTK RFKPF ENV: 661-774 AAEIFKSD LDKVERASKK FPYVCTTYSC TEHWCTGALT RWQAWLLEAM PAAYMEIGDA LAKEKGITNG ERIRVSSVRG SVTCVAMVTK RFKPFTIEGK TVHQVGMPFN YGWLFP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MTNHYTDMR NSDCILIMGS NAAEHHPMAF RWMLKAKERG ATLIHVDPRY TRTSARCDYH VPLRSGTDIA FLGGMINYIL SNDKWFKEYV LYYTNASFIV GKDYTFNDGL FSGYDAEKRK YNKDTWVLEK DDAGIPKRDM TLTDPRCVFQ MMKAHYSRYS MDKVSSVTGV SKENLLKVYQ AYSATGVPDK AGTECYALGW THHTVGSQNI RTMSIIQLLL GNMGIAGGGI NAMRGEPNVQ GSTDQAVLYN ILPGYLKMPS ASIDTIDHYL EKYTPVSKDP QSANYYQNYP KFFISFLKAL FDDKATKENG FGYNWLPKLD DGKHYSTMHL FDAMYAGKVK GYFCVGADTA VSTPNTTKVR KAMENLEWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PAAATMEKEG SQSNSGRMIQ WKYKAAEAPG DGLPVGEIEI KIMKAVKELY VKEGGPNAEP IVNLYWDYLD GKGHFDALKV CKRLNGFFLQ DTVIEDKAKG TKTEYKKGQL VPGFGNLQDD GSTASGNWVH CGSFGADGEN KMAKRGKEDP TGLGIYPNWA YVWPVNRRIM YNRASCDPTG KPWDPKRKVL EWVGDKWVGD VPDGPWPPLA DKENGKLPFI MKTDGVGAIF GPGMVDGPFP EHYEPLEGPL DKNPLNGQLF NPAAEIFKSD LDKVERASKK FPYVCTTYSC TEHWCTGALT RWQAWLLEAM PAAYMEIGDA LAKEKGITNG ERIRVSSVRG SVTCVAMVTK RFKPFTIEGK TVHQVGMPFN YGWLFPKGTK DDSTNFLTPT VGDANTFCPE YKAFMVNVEK L HMM: 244-338 AVLYN ILPGYLKMPS ASIDTIDHYL EKYTPVSKDP QSANYYQNYP KFFISFLKAL FDDKATKENG FGYNWLPKLD DGKHYSTMHL FDAMYAGKVK ALI: 8-102 R NSDCILIMGS NAAEHHPMAF RWMLKAKERG ATLIHVDPRY TRTSARCDYH VPLRSGTDIA FLGGMINYIL SNDKWFKEYV LYYTNASFIV GKDY ENV: 2-239 NHYTDMR NSDCILIMGS NAAEHHPMAF RWMLKAKERG ATLIHVDPRY TRTSARCDYH VPLRSGTDIA FLGGMINYIL SNDKWFKEYV LYYTNASFIV GKDYTFNDGL FSGYDAEKRK YNKDTWVLEK DDAGIPKRDM TLTDPRCVFQ MMKAHYSRYS MDKVSSVTGV SKENLLKVYQ AYSATGVPDK AGTECYALGW THHTVGSQNI RTMSIIQLLL GNMGIAGGGI NAMRGEPNVQ G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MTNHYTDMR NSDCILIMGS NAAEHHPMAF RWMLKAKERG ATLIHVDPRY TRTSARCDYH VPLRSGTDIA FLGGMINYIL SNDKWFKEYV LYYTNASFIV GKDYTFNDGL FSGYDAEKRK YNKDTWVLEK DDAGIPKRDM TLTDPRCVFQ MMKAHYSRYS MDKVSSVTGV SKENLLKVYQ AYSATGVPDK AGTECYALGW THHTVGSQNI RTMSIIQLLL GNMGIAGGGI NAMRGEPNVQ GSTDQAVLYN ILPGYLKMPS ASIDTIDHYL EKYTPVSKDP QSANYYQNYP KFFISFLKAL FDDKATKENG FGYNWLPKLD DGKHYSTMHL FDAMYAGKVK GYFCVGADTA VSTPNTTKVR KAMENLEWLV GENIFNNETY EFWRGPGVDP KKIKTECFLL PAAATMEKEG SQSNSGRMIQ WKYKAAEAPG DGLPVGEIEI KIMKAVKELY VKEGGPNAEP IVNLYWDYLD GKGHFDALKV CKRLNGFFLQ DTVIEDKAKG TKTEYKKGQL VPGFGNLQDD GSTASGNWVH CGSFGADGEN KMAKRGKEDP TGLGIYPNWA YVWPVNRRIM YNRASCDPTG KPWDPKRKVL EWVGDKWVGD VPDGPWPPLA DKENGKLPFI MKTDGVGAIF GPGMVDGPFP EHYEPLEGPL DKNPLNGQLF NPAAEIFKSD LDKVERASKK FPYVCTTYSC TEHWCTGALT RWQAWLLEAM PAAYMEIGDA LAKEKGITNG ERIRVSSVRG SVTCVAMVTK RFKPFTIEGK TVHQVGMPFN YGWLFPKGTK DDSTNFLTPT VGDANTFCPE YKAFMVNVEK L HMM: 231-366 MRGEPNVQ GSTDQAVLYN ILPGYLKMPS ASIDTIDHYL EKYTPVSKDP QSANYYQNYP KFFISFLKAL FDDKATKENG FGYNWLPKLD DGKHYSTMHL FDAMYAGKVK GYFCVGADTA VSTPNTTKVR KAMENLEW ALI: 11-132 DCILIMGS NAAEHHPMAF RWMLKAKERG ATLIHVDPRY TRTSARCDYH VPLRSGTDIA FLGGMINYIL SNDKWFKEYV LYYTNASFIV GKDYTFNDGL FSGYDAEKRK YNKDTWVLEK DDAG ENV: 3-246 HYTDMR NSDCILIMGS NAAEHHPMAF RWMLKAKERG ATLIHVDPRY TRTSARCDYH VPLRSGTDIA FLGGMINYIL SNDKWFKEYV LYYTNASFIV GKDYTFNDGL FSGYDAEKRK YNKDTWVLEK DDAGIPKRDM TLTDPRCVFQ MMKAHYSRYS MDKVSSVTGV SKENLLKVYQ AYSATGVPDK AGTECYALGW THHTVGSQNI RTMSIIQLLL GNMGIAGGGI NAMRGEPNVQ GSTDQAVL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810
Sequence: MVKIRSIIN GSEVFAPPGA TIFEAAQQAG IDIPTLCHHR KLHPIGACRI CVVEIKGQRS LQTACTFPVA EGMEIETESP RVVSARKFIL GMLFSERNHL CPFCEASGDC ELQNLGYRYG IDHWFYPTFT KPFPLDASRG YFIMNHNRCV LCQRCARACN ELVANHTLGL RQRGADSMIN CDANLPYVKS TCISCGTCLQ ICPTGALSDP RSSFMGRDAQ TERTRSICNK CSVGCGTSIV TRAGNVLRIE GDWDAPVNGG LLCKMGRFEP LYDQRKRTTQ PMLRRQGKLE PVTWEEALQG IADHINKADA KEVGLLVSGD ATNEALYLAS RLFKEQLSAA NVGLLSGAVP DLFDEKPGAF STLSESDLIL LIGADPAKDQ PVSSFMVKRL VDKGVRLIVV DDGENGLRPF ADATFKSGDL AGAIEIADRV ESVAVLYGTG LTAEAAQSLK KLGAKARFVA LEPGVNSRAA AKFGLNNGFQ ASTAKVLYAL LGEQDQGGDD VLAKVDKEAF VIVQAGYAFP LLNRADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGKNLG ASFAEISACA AKELE
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590
PF13510: 6-78 ◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
PF10588: 84-122 ◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
PF00037: 186-206 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF04879: 220-267 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00384: 437-572 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MVKIRSIIN GSEVFAPPGA TIFEAAQQAG IDIPTLCHHR KLHPIGACRI CVVEIKGQRS LQTACTFPVA EGMEIETESP RVVSARKFIL GMLFSERNHL CPFCEASGDC ELQNLGYRYG IDHWFYPTFT KPFPLDASRG YFIMNHNRCV LCQRCARACN ELVANHTLGL RQRGADSMIN CDANLPYVKS TCISCGTCLQ ICPTGALSDP RSSFMGRDAQ TERTRSICNK CSVGCGTSIV TRAGNVLRIE GDWDAPVNGG LLCKMGRFEP LYDQRKRTTQ PMLRRQGKLE PVTWEEALQG IADHINKADA KEVGLLVSGD ATNEALYLAS RLFKEQLSAA NVGLLSGAVP DLFDEKPGAF STLSESDLIL LIGADPAKDQ PVSSFMVKRL VDKGVRLIVV DDGENGLRPF ADATFKSGDL AGAIEIADRV ESVAVLYGTG LTAEAAQSLK KLGAKARFVA LEPGVNSRAA AKFGLNNGFQ ASTAKVLYAL LGEQDQGGDD VLAKVDKEAF VIVQAGYAFP LLNRADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGKNLG ASFAEISACA AKELE HMM: 134-155 DASRG YFIMNHNRCV LCQRCAR ALI: 283-304 RQGKLE PVTWEEALQG IADHIN ENV: 256-317 NGG LLCKMGRFEP LYDQRKRTTQ PMLRRQGKLE PVTWEEALQG IADHINKADA KEVGLLVSG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590
Sequence: MVKIRSIIN GSEVFAPPGA TIFEAAQQAG IDIPTLCHHR KLHPIGACRI CVVEIKGQRS LQTACTFPVA EGMEIETESP RVVSARKFIL GMLFSERNHL CPFCEASGDC ELQNLGYRYG IDHWFYPTFT KPFPLDASRG YFIMNHNRCV LCQRCARACN ELVANHTLGL RQRGADSMIN CDANLPYVKS TCISCGTCLQ ICPTGALSDP RSSFMGRDAQ TERTRSICNK CSVGCGTSIV TRAGNVLRIE GDWDAPVNGG LLCKMGRFEP LYDQRKRTTQ PMLRRQGKLE PVTWEEALQG IADHINKADA KEVGLLVSGD ATNEALYLAS RLFKEQLSAA NVGLLSGAVP DLFDEKPGAF STLSESDLIL LIGADPAKDQ PVSSFMVKRL VDKGVRLIVV DDGENGLRPF ADATFKSGDL AGAIEIADRV ESVAVLYGTG LTAEAAQSLK KLGAKARFVA LEPGVNSRAA AKFGLNNGFQ ASTAKVLYAL LGEQDQGGDD VLAKVDKEAF VIVQAGYAFP LLNRADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGKNLG ASFAEISACA AKELE HMM: 627-681 ALI: 522-574 RADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLG ENV: 496-586 GDD VLAKVDKEAF VIVQAGYAFP LLNRADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGKNLG ASFAEISA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590
Sequence: MVKIRSIIN GSEVFAPPGA TIFEAAQQAG IDIPTLCHHR KLHPIGACRI CVVEIKGQRS LQTACTFPVA EGMEIETESP RVVSARKFIL GMLFSERNHL CPFCEASGDC ELQNLGYRYG IDHWFYPTFT KPFPLDASRG YFIMNHNRCV LCQRCARACN ELVANHTLGL RQRGADSMIN CDANLPYVKS TCISCGTCLQ ICPTGALSDP RSSFMGRDAQ TERTRSICNK CSVGCGTSIV TRAGNVLRIE GDWDAPVNGG LLCKMGRFEP LYDQRKRTTQ PMLRRQGKLE PVTWEEALQG IADHINKADA KEVGLLVSGD ATNEALYLAS RLFKEQLSAA NVGLLSGAVP DLFDEKPGAF STLSESDLIL LIGADPAKDQ PVSSFMVKRL VDKGVRLIVV DDGENGLRPF ADATFKSGDL AGAIEIADRV ESVAVLYGTG LTAEAAQSLK KLGAKARFVA LEPGVNSRAA AKFGLNNGFQ ASTAKVLYAL LGEQDQGGDD VLAKVDKEAF VIVQAGYAFP LLNRADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGKNLG ASFAEISACA AKELE HMM: 153-176 CARACN ELVANHTLGL RQRGADSM ALI: 283-306 RQGKLE PVTWEEALQG IADHINKA ENV: 265-314 RFEP LYDQRKRTTQ PMLRRQGKLE PVTWEEALQG IADHINKADA KEVGLL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590
Sequence: MVKIRSIIN GSEVFAPPGA TIFEAAQQAG IDIPTLCHHR KLHPIGACRI CVVEIKGQRS LQTACTFPVA EGMEIETESP RVVSARKFIL GMLFSERNHL CPFCEASGDC ELQNLGYRYG IDHWFYPTFT KPFPLDASRG YFIMNHNRCV LCQRCARACN ELVANHTLGL RQRGADSMIN CDANLPYVKS TCISCGTCLQ ICPTGALSDP RSSFMGRDAQ TERTRSICNK CSVGCGTSIV TRAGNVLRIE GDWDAPVNGG LLCKMGRFEP LYDQRKRTTQ PMLRRQGKLE PVTWEEALQG IADHINKADA KEVGLLVSGD ATNEALYLAS RLFKEQLSAA NVGLLSGAVP DLFDEKPGAF STLSESDLIL LIGADPAKDQ PVSSFMVKRL VDKGVRLIVV DDGENGLRPF ADATFKSGDL AGAIEIADRV ESVAVLYGTG LTAEAAQSLK KLGAKARFVA LEPGVNSRAA AKFGLNNGFQ ASTAKVLYAL LGEQDQGGDD VLAKVDKEAF VIVQAGYAFP LLNRADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGKNLG ASFAEISACA AKELE HMM: 647-701 ALI: 524-576 DVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGKN ENV: 521-583 NRADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGKNLG ASFAE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590
Sequence: MVKIRSIIN GSEVFAPPGA TIFEAAQQAG IDIPTLCHHR KLHPIGACRI CVVEIKGQRS LQTACTFPVA EGMEIETESP RVVSARKFIL GMLFSERNHL CPFCEASGDC ELQNLGYRYG IDHWFYPTFT KPFPLDASRG YFIMNHNRCV LCQRCARACN ELVANHTLGL RQRGADSMIN CDANLPYVKS TCISCGTCLQ ICPTGALSDP RSSFMGRDAQ TERTRSICNK CSVGCGTSIV TRAGNVLRIE GDWDAPVNGG LLCKMGRFEP LYDQRKRTTQ PMLRRQGKLE PVTWEEALQG IADHINKADA KEVGLLVSGD ATNEALYLAS RLFKEQLSAA NVGLLSGAVP DLFDEKPGAF STLSESDLIL LIGADPAKDQ PVSSFMVKRL VDKGVRLIVV DDGENGLRPF ADATFKSGDL AGAIEIADRV ESVAVLYGTG LTAEAAQSLK KLGAKARFVA LEPGVNSRAA AKFGLNNGFQ ASTAKVLYAL LGEQDQGGDD VLAKVDKEAF VIVQAGYAFP LLNRADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGKNLG ASFAEISACA AKELE HMM: 137-162 RG YFIMNHNRCV LCQRCARACN ELVA ALI: 283-308 RQGKLE PVTWEEALQG IADHINKADA ENV: 261-326 CKMGRFEP LYDQRKRTTQ PMLRRQGKLE PVTWEEALQG IADHINKADA KEVGLLVSGD ATNEALYL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590
Sequence: MVKIRSIIN GSEVFAPPGA TIFEAAQQAG IDIPTLCHHR KLHPIGACRI CVVEIKGQRS LQTACTFPVA EGMEIETESP RVVSARKFIL GMLFSERNHL CPFCEASGDC ELQNLGYRYG IDHWFYPTFT KPFPLDASRG YFIMNHNRCV LCQRCARACN ELVANHTLGL RQRGADSMIN CDANLPYVKS TCISCGTCLQ ICPTGALSDP RSSFMGRDAQ TERTRSICNK CSVGCGTSIV TRAGNVLRIE GDWDAPVNGG LLCKMGRFEP LYDQRKRTTQ PMLRRQGKLE PVTWEEALQG IADHINKADA KEVGLLVSGD ATNEALYLAS RLFKEQLSAA NVGLLSGAVP DLFDEKPGAF STLSESDLIL LIGADPAKDQ PVSSFMVKRL VDKGVRLIVV DDGENGLRPF ADATFKSGDL AGAIEIADRV ESVAVLYGTG LTAEAAQSLK KLGAKARFVA LEPGVNSRAA AKFGLNNGFQ ASTAKVLYAL LGEQDQGGDD VLAKVDKEAF VIVQAGYAFP LLNRADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGKNLG ASFAEISACA AKELE HMM: 630-685 ALI: 522-575 RADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGK ENV: 499-585 VLAKVDKEAF VIVQAGYAFP LLNRADVVLP SAIWSERTGS LTNTEGSVQM AAKAVEPAGE ARPDWEILSL LADRLGKNLG ASFAEIS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590
Sequence: MDFALSEEL EMLRTMARDF AAEKIAPFAD KWDEEHYFPY EEVVKPMGEL GFFGTVIPEE YGGNNMGWLA AIILTEEVAR ASSALRVQIN MEGLGCAYTI WKYGTEEAKK KYVEKLATGQ YLGGFGITEF NAGSDVMSMK STAEDKGDHY VLNGSKTWIS NASCADVIVY YAYTDKAAKG KGLSAFAVEL KNNPGIRTTD LDKMGSKSSP TGEIYLDNVI VPKENLLGKP GQGAQIVFGS LNGTRLSAAA GGIGLAQACL DAAIKYANER EQFGKPIGSF QANQFLIGEM ACDLEAARMM VYKAAWQKDQ GNLGNTFEVA QAKYLAGEVA YKCAIGAMRI FGAYGYSTEY PVNRYYRDAP TYAMVEGSTN VCKMIVGGAL LGAK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-119 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
PF02770: 122-218 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 229-379 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌
Sequence: MDFALSEEL EMLRTMARDF AAEKIAPFAD KWDEEHYFPY EEVVKPMGEL GFFGTVIPEE YGGNNMGWLA AIILTEEVAR ASSALRVQIN MEGLGCAYTI WKYGTEEAKK KYVEKLATGQ YLGGFGITEF NAGSDVMSMK STAEDKGDHY VLNGSKTWIS NASCADVIVY YAYTDKAAKG KGLSAFAVEL KNNPGIRTTD LDKMGSKSSP TGEIYLDNVI VPKENLLGKP GQGAQIVFGS LNGTRLSAAA GGIGLAQACL DAAIKYANER EQFGKPIGSF QANQFLIGEM ACDLEAARMM VYKAAWQKDQ GNLGNTFEVA QAKYLAGEVA YKCAIGAMRI FGAYGYSTEY PVNRYYRDAP TYAMVEGSTN VCKMIVGGAL LGAK HMM: 56-391 PEE YGGNNMGWLA AIILTEEVAR ASSALRVQIN MEGLGCAYTI WKYGTEEAKK KYVEKLATGQ YLGGFGITEF NAGSDVMSMK STAEDKGDHY VLNGSKTWIS NASCADVIVY YAYTDKAAKG KGLSAFAVEL KNNPGIRTTD LDKMGSKSSP TGEIYLDNVI VPKENLLGKP GQGAQIVFGS LNGTRLSAAA GGIGLAQACL DAAIKYANER EQFGKPIGSF QANQFLIGEM ACDLEAARMM VYKAAWQKDQ GNLGNTFEVA QAKYLAGEVA YKCAIGAMRI FGAYGYSTEY PVNRYYRDAP TYAMVEGSTN VCKMIVGGAL LGAK ALI: 50-364 FFGTVIPEE YGGNNMGWLA AIILTEEVAR ASSALRVQIN MEGLGCAYTI WKYGTEEAKK KYVEKLATGQ YLGGFGITEF NAGSDVMSMK STAEDKGDHY VLNGSKTWIS NASCADVIVY YAYTDKAAKG KGLSAFAVEL KNNPGIRTTD LDKMGSKSSP TGEIYLDNVI VPKENLLGKP GQGAQIVFGS LNGTRLSAAA GGIGLAQACL DAAIKYANER EQFGKPIGSF QANQFLIGEM ACDLEAARMM VYKAAWQKDQ GNLGNTFEVA QAKYLAGEVA YKCAIGAMRI FGAYGYSTEY PVNRYYRDAP TYAMVE ENV: 41-377 VVKPMGEL GFFGTVIPEE YGGNNMGWLA AIILTEEVAR ASSALRVQIN MEGLGCAYTI WKYGTEEAKK KYVEKLATGQ YLGGFGITEF NAGSDVMSMK STAEDKGDHY VLNGSKTWIS NASCADVIVY YAYTDKAAKG KGLSAFAVEL KNNPGIRTTD LDKMGSKSSP TGEIYLDNVI VPKENLLGKP GQGAQIVFGS LNGTRLSAAA GGIGLAQACL DAAIKYANER EQFGKPIGSF QANQFLIGEM ACDLEAARMM VYKAAWQKDQ GNLGNTFEVA QAKYLAGEVA YKCAIGAMRI FGAYGYSTEY PVNRYYRDAP TYAMVEGSTN VCKMIVGGA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDFELDQEL LALKESVQKL VQEKVAPRAG ELDEIGGYPW DIKEAFAENR ILAIPFPSEY GGTGGKALPM AIAVEEISKA SCSVAMMLSG QCLGSAAITI AGTEEQKQQF LPDLAKGKTL AAYGLTEPDA GSDVASLQTT AVRDGDDYVV TGSKRFITYG DIADVMTLFV KTVDPATKEK KVSCLVAERG TGWIVSKLEH KIGIKGSTTT ELFLDELRVP VKNLLGKEGD GFKIAMQVLD KTRTSIAAQA VGMAQGALDC AVQFAREHLQ NGKPIGRKQG IQMKLADMEM KTEAARFLTY MAADKYDRHD PDRGRYSACA KAYASDLAME VIGGAIQVLG EYGYTKKYPV ERMFRDAKVQ QIYEGTNEIQ RIVIARSLLG KGF
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 7-117 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 120-215 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00441: 227-378 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MDFELDQEL LALKESVQKL VQEKVAPRAG ELDEIGGYPW DIKEAFAENR ILAIPFPSEY GGTGGKALPM AIAVEEISKA SCSVAMMLSG QCLGSAAITI AGTEEQKQQF LPDLAKGKTL AAYGLTEPDA GSDVASLQTT AVRDGDDYVV TGSKRFITYG DIADVMTLFV KTVDPATKEK KVSCLVAERG TGWIVSKLEH KIGIKGSTTT ELFLDELRVP VKNLLGKEGD GFKIAMQVLD KTRTSIAAQA VGMAQGALDC AVQFAREHLQ NGKPIGRKQG IQMKLADMEM KTEAARFLTY MAADKYDRHD PDRGRYSACA KAYASDLAME VIGGAIQVLG EYGYTKKYPV ERMFRDAKVQ QIYEGTNEIQ RIVIARSLLG KGF HMM: 24-391 APRAG ELDEIGGYPW DIKEAFAENR ILAIPFPSEY GGTGGKALPM AIAVEEISKA SCSVAMMLSG QCLGSAAITI AGTEEQKQQF LPDLAKGKTL AAYGLTEPDA GSDVASLQTT AVRDGDDYVV TGSKRFITYG DIADVMTLFV KTVDPATKEK KVSCLVAERG TGWIVSKLEH KIGIKGSTTT ELFLDELRVP VKNLLGKEGD GFKIAMQVLD KTRTSIAAQA VGMAQGALDC AVQFAREHLQ NGKPIGRKQG IQMKLADMEM KTEAARFLTY MAADKYDRHD PDRGRYSACA KAYASDLAME VIGGAIQVLG EYGYTKKYPV ERMFRDAKVQ QIYEGTNEIQ RIVIARSLLG KGF ALI: 17-362 KL VQEKVAPRAG ELDEIGGYPW DIKEAFAENR ILAIPFPSEY GGTGGKALPM AIAVEEISKA SCSVAMMLSG QCLGSAAITI AGTEEQKQQF LPDLAKGKTL AAYGLTEPDA GSDVASLQTT AVRDGDDYVV TGSKRFITYG DIADVMTLFV KTVDPATKEK KVSCLVAERG TGWIVSKLEH KIGIKGSTTT ELFLDELRVP VKNLLGKEGD GFKIAMQVLD KTRTSIAAQA VGMAQGALDC AVQFAREHLQ NGKPIGRKQG IQMKLADMEM KTEAARFLTY MAADKYDRHD PDRGRYSACA KAYASDLAME VIGGAIQVLG EYGYTKKYPV ERMFRDAKVQ QIYE ENV: 10-372 ALKESVQKL VQEKVAPRAG ELDEIGGYPW DIKEAFAENR ILAIPFPSEY GGTGGKALPM AIAVEEISKA SCSVAMMLSG QCLGSAAITI AGTEEQKQQF LPDLAKGKTL AAYGLTEPDA GSDVASLQTT AVRDGDDYVV TGSKRFITYG DIADVMTLFV KTVDPATKEK KVSCLVAERG TGWIVSKLEH KIGIKGSTTT ELFLDELRVP VKNLLGKEGD GFKIAMQVLD KTRTSIAAQA VGMAQGALDC AVQFAREHLQ NGKPIGRKQG IQMKLADMEM KTEAARFLTY MAADKYDRHD PDRGRYSACA KAYASDLAME VIGGAIQVLG EYGYTKKYPV ERMFRDAKVQ QIYEGTNEIQ RIVI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDFELDKDL LALKESVQKV VQETVAARAG ELDEIGGYPW DIKEAFAENK ILAIPFPKEY GGTGGTALQM CIATEEVSKA SCSVAMILTG QCLGSAAITI AGTEEQKQRF LPDLASGKTL AAYGLTEPDA GSDVASLQTT AVRDGDDYVV TGTKRFITYG DIADVMTLFV KTVDPNTKEK KVSCLVAEKG PGWIVSKLEH KIGIKGSTTT ELFLDGLRVP VKNLLGKEGD GFKIAMQVLD KTRTTIAAQA LGMAQSALDC AVQFAREHLE GGKPIGRKQG IQMKLADMEM KTQAARCISL FAADRYDHHD PNQSRYSSCA KAFATDMAME VIGAAIQVLG EYGYTKQYPV ERMFRDAKVQ QIYEGTNEIQ RIVIARSLLG KGF
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 9-117 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦
PF02770: 120-215 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
PF00441: 227-378 ◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MDFELDKDL LALKESVQKV VQETVAARAG ELDEIGGYPW DIKEAFAENK ILAIPFPKEY GGTGGTALQM CIATEEVSKA SCSVAMILTG QCLGSAAITI AGTEEQKQRF LPDLASGKTL AAYGLTEPDA GSDVASLQTT AVRDGDDYVV TGTKRFITYG DIADVMTLFV KTVDPNTKEK KVSCLVAEKG PGWIVSKLEH KIGIKGSTTT ELFLDGLRVP VKNLLGKEGD GFKIAMQVLD KTRTTIAAQA LGMAQSALDC AVQFAREHLE GGKPIGRKQG IQMKLADMEM KTQAARCISL FAADRYDHHD PNQSRYSSCA KAFATDMAME VIGAAIQVLG EYGYTKQYPV ERMFRDAKVQ QIYEGTNEIQ RIVIARSLLG KGF HMM: 23-391 VAARAG ELDEIGGYPW DIKEAFAENK ILAIPFPKEY GGTGGTALQM CIATEEVSKA SCSVAMILTG QCLGSAAITI AGTEEQKQRF LPDLASGKTL AAYGLTEPDA GSDVASLQTT AVRDGDDYVV TGTKRFITYG DIADVMTLFV KTVDPNTKEK KVSCLVAEKG PGWIVSKLEH KIGIKGSTTT ELFLDGLRVP VKNLLGKEGD GFKIAMQVLD KTRTTIAAQA LGMAQSALDC AVQFAREHLE GGKPIGRKQG IQMKLADMEM KTQAARCISL FAADRYDHHD PNQSRYSSCA KAFATDMAME VIGAAIQVLG EYGYTKQYPV ERMFRDAKVQ QIYEGTNEIQ RIVIARSLLG KGF ALI: 16-362 QKV VQETVAARAG ELDEIGGYPW DIKEAFAENK ILAIPFPKEY GGTGGTALQM CIATEEVSKA SCSVAMILTG QCLGSAAITI AGTEEQKQRF LPDLASGKTL AAYGLTEPDA GSDVASLQTT AVRDGDDYVV TGTKRFITYG DIADVMTLFV KTVDPNTKEK KVSCLVAEKG PGWIVSKLEH KIGIKGSTTT ELFLDGLRVP VKNLLGKEGD GFKIAMQVLD KTRTTIAAQA LGMAQSALDC AVQFAREHLE GGKPIGRKQG IQMKLADMEM KTQAARCISL FAADRYDHHD PNQSRYSSCA KAFATDMAME VIGAAIQVLG EYGYTKQYPV ERMFRDAKVQ QIYE ENV: 5-371 DKDL LALKESVQKV VQETVAARAG ELDEIGGYPW DIKEAFAENK ILAIPFPKEY GGTGGTALQM CIATEEVSKA SCSVAMILTG QCLGSAAITI AGTEEQKQRF LPDLASGKTL AAYGLTEPDA GSDVASLQTT AVRDGDDYVV TGTKRFITYG DIADVMTLFV KTVDPNTKEK KVSCLVAEKG PGWIVSKLEH KIGIKGSTTT ELFLDGLRVP VKNLLGKEGD GFKIAMQVLD KTRTTIAAQA LGMAQSALDC AVQFAREHLE GGKPIGRKQG IQMKLADMEM KTQAARCISL FAADRYDHHD PNQSRYSSCA KAFATDMAME VIGAAIQVLG EYGYTKQYPV ERMFRDAKVQ QIYEGTNEIQ RIV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MENLLTDET KMFQQMMHRF CEKEIKPVAG EIDEKEEYPS EILAKLAEMG VGGILAPEQY GGSGLGWVGA CIAMEELARV SAAAALAVGA TSFYFAYPIL VAGSEEQKEK YVTAAAYGEK TGTLALTESG SGPDIAKIET TAETKGDSLV LKGSKMSVIN ADNADEMLVF ARMTNNGQPG DFVLVAVDSK SPGIVIRKVP KMGMSAVATC EVDFNEVEVA KEAVIASGME SLKLITNALD CFRLVFGAVS IGILQGAFEE ALSYSQSRMA FGKPICAFQA VGFYLADMYK MGRVARNMIY QAAFKADQGL DISLDAQVAK LYASESCMWV ADRSLQIHGG YGFSVEYPIS RFFREARLME VGEGTSETLK ETILVRLGLQ T
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 122-216 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 231-375 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
Sequence: MENLLTDET KMFQQMMHRF CEKEIKPVAG EIDEKEEYPS EILAKLAEMG VGGILAPEQY GGSGLGWVGA CIAMEELARV SAAAALAVGA TSFYFAYPIL VAGSEEQKEK YVTAAAYGEK TGTLALTESG SGPDIAKIET TAETKGDSLV LKGSKMSVIN ADNADEMLVF ARMTNNGQPG DFVLVAVDSK SPGIVIRKVP KMGMSAVATC EVDFNEVEVA KEAVIASGME SLKLITNALD CFRLVFGAVS IGILQGAFEE ALSYSQSRMA FGKPICAFQA VGFYLADMYK MGRVARNMIY QAAFKADQGL DISLDAQVAK LYASESCMWV ADRSLQIHGG YGFSVEYPIS RFFREARLME VGEGTSETLK ETILVRLGLQ T HMM: 52-293 ILAPEQY GGSGLGWVGA CIAMEELARV SAAAALAVGA TSFYFAYPIL VAGSEEQKEK YVTAAAYGEK TGTLALTESG SGPDIAKIET TAETKGDSLV LKGSKMSVIN ADNADEMLVF ARMTNNGQPG DFVLVAVDSK SPGIVIRKVP KMGMSAVATC EVDFNEVEVA KEAVIASGME SLKLITNALD CFRLVFGAVS IGILQGAFEE ALSYSQSRMA FGKPICAFQA VGFYLADMYK MGRVA ALI: 45-280 AEMG VGGILAPEQY GGSGLGWVGA CIAMEELARV SAAAALAVGA TSFYFAYPIL VAGSEEQKEK YVTAAAYGEK TGTLALTESG SGPDIAKIET TAETKGDSLV LKGSKMSVIN ADNADEMLVF ARMTNNGQPG DFVLVAVDSK SPGIVIRKVP KMGMSAVATC EVDFNEVEVA KEAVIASGME SLKLITNALD CFRLVFGAVS IGILQGAFEE ALSYSQSRMA FGKPICAFQA VG ENV: 21-370 KEIKPVAG EIDEKEEYPS EILAKLAEMG VGGILAPEQY GGSGLGWVGA CIAMEELARV SAAAALAVGA TSFYFAYPIL VAGSEEQKEK YVTAAAYGEK TGTLALTESG SGPDIAKIET TAETKGDSLV LKGSKMSVIN ADNADEMLVF ARMTNNGQPG DFVLVAVDSK SPGIVIRKVP KMGMSAVATC EVDFNEVEVA KEAVIASGME SLKLITNALD CFRLVFGAVS IGILQGAFEE ALSYSQSRMA FGKPICAFQA VGFYLADMYK MGRVARNMIY QAAFKADQGL DISLDAQVAK LYASESCMWV ADRSLQIHGG YGFSVEYPIS RFFREARLME VGEGTSETLK ET Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MEIIQYTQE HRIFREAVKK FLAREIVPHI EEWEEAGIVS REAWKRMGAQ GFLGMSVPEA YGGPTADFLY EVIVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKHR YLPGCISGDI ITAIGMTEPN TGSDLAAIRT TAVEDGDGFV INGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVDA GTPGFEKGRN LKKIGWHSQD TAELFFADCR IPRANRLGEK GTGFRKMMEM LQQERLVVAI GAQVIAEFML EKTIAYCRER KVFGRPISRF QNSQFEFAEM ATEIQIGRTF IDKMIVDHME GKDLTREVSM AKYWITDMAG KVADRCLQLH GGYGYCEEYP IARAWRDIRI MRIYAGSNEI MKVIIARTLG L
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 6-118 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 121-218 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
PF00441: 229-378 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌
Sequence: MEIIQYTQE HRIFREAVKK FLAREIVPHI EEWEEAGIVS REAWKRMGAQ GFLGMSVPEA YGGPTADFLY EVIVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKHR YLPGCISGDI ITAIGMTEPN TGSDLAAIRT TAVEDGDGFV INGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVDA GTPGFEKGRN LKKIGWHSQD TAELFFADCR IPRANRLGEK GTGFRKMMEM LQQERLVVAI GAQVIAEFML EKTIAYCRER KVFGRPISRF QNSQFEFAEM ATEIQIGRTF IDKMIVDHME GKDLTREVSM AKYWITDMAG KVADRCLQLH GGYGYCEEYP IARAWRDIRI MRIYAGSNEI MKVIIARTLG L HMM: 23-233 EIVPHI EEWEEAGIVS REAWKRMGAQ GFLGMSVPEA YGGPTADFLY EVIVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKHR YLPGCISGDI ITAIGMTEPN TGSDLAAIRT TAVEDGDGFV INGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVDA GTPGFEKGRN LKKIGWHSQD TAELFFADCR IPRANRLGEK GTGFR ALI: 17-228 KK FLAREIVPHI EEWEEAGIVS REAWKRMGAQ GFLGMSVPEA YGGPTADFLY EVIVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKHR YLPGCISGDI ITAIGMTEPN TGSDLAAIRT TAVEDGDGFV INGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVDA GTPGFEKGRN LKKIGWHSQD TAELFFADCR IPRANRLGEK ENV: 6-262 TQE HRIFREAVKK FLAREIVPHI EEWEEAGIVS REAWKRMGAQ GFLGMSVPEA YGGPTADFLY EVIVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKHR YLPGCISGDI ITAIGMTEPN TGSDLAAIRT TAVEDGDGFV INGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVDA GTPGFEKGRN LKKIGWHSQD TAELFFADCR IPRANRLGEK GTGFRKMMEM LQQERLVVAI GAQVIAEFML EKTI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MEIIQYTQE HRIFREAVKK FLAREIVPHI EEWEEAGIVS REAWKRMGAQ GFLGMSVPEA YGGPTADFLY EVIVIEELAR TNFTGLAARL HNTVVLPYLI EYGSEEQKHR YLPGCISGDI ITAIGMTEPN TGSDLAAIRT TAVEDGDGFV INGQKTFISN GINCDLIVLV ARDPAVEDPH KAIDLYLVDA GTPGFEKGRN LKKIGWHSQD TAELFFADCR IPRANRLGEK GTGFRKMMEM LQQERLVVAI GAQVIAEFML EKTIAYCRER KVFGRPISRF QNSQFEFAEM ATEIQIGRTF IDKMIVDHME GKDLTREVSM AKYWITDMAG KVADRCLQLH GGYGYCEEYP IARAWRDIRI MRIYAGSNEI MKVIIARTLG L HMM: 339-390 GGYGYCEEYP IARAWRDIRI MRIYAGSNEI MKVIIARTLG L ALI: 311-362 DLTREVSM AKYWITDMAG KVADRCLQLH GGYGYCEEYP IARAWRDIRI MRIY ENV: 286-373 AEM ATEIQIGRTF IDKMIVDHME GKDLTREVSM AKYWITDMAG KVADRCLQLH GGYGYCEEYP IARAWRDIRI MRIYAGSNEI MKVII Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MENLLTDET KMFQQMMHRF CEKEIKPVAG EIDEKEEYPS EILGKLAEMG VGGIIAPEQY GGSGLGWVGA CIAMEELSRV SSAVALAAGA TSFYFAYPIL VAGSEEQKEK YVTAAAYGEK TGTLALTEAG CGPDIAKIQT TAEVKGDSLV LKGSKMSVTN ADNVDYILVF ARMINDGQPG DYILVVVDSK SPGITLRKVP KMGMSAVSTC EIDFNEVEAP KGAVISSGTE CFDLITNAID CFRLVFGAVG LGIMQGAFEE ALTYSQSRVA FGKPICSFQA VGFYLADMFK MSRIARNMIY QAAFKADQGL DISLDAQVAK LFASESCMWV ADRALQIHGG YGFSIEYPIS RFFREARLME VGEGTSETLK ETILVKLGIP T
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
PF02771: 5-118 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
PF02770: 122-216 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 230-372 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌
Sequence: MENLLTDET KMFQQMMHRF CEKEIKPVAG EIDEKEEYPS EILGKLAEMG VGGIIAPEQY GGSGLGWVGA CIAMEELSRV SSAVALAAGA TSFYFAYPIL VAGSEEQKEK YVTAAAYGEK TGTLALTEAG CGPDIAKIQT TAEVKGDSLV LKGSKMSVTN ADNVDYILVF ARMINDGQPG DYILVVVDSK SPGITLRKVP KMGMSAVSTC EIDFNEVEAP KGAVISSGTE CFDLITNAID CFRLVFGAVG LGIMQGAFEE ALTYSQSRVA FGKPICSFQA VGFYLADMFK MSRIARNMIY QAAFKADQGL DISLDAQVAK LFASESCMWV ADRALQIHGG YGFSIEYPIS RFFREARLME VGEGTSETLK ETILVKLGIP T HMM: 52-286 IIAPEQY GGSGLGWVGA CIAMEELSRV SSAVALAAGA TSFYFAYPIL VAGSEEQKEK YVTAAAYGEK TGTLALTEAG CGPDIAKIQT TAEVKGDSLV LKGSKMSVTN ADNVDYILVF ARMINDGQPG DYILVVVDSK SPGITLRKVP KMGMSAVSTC EIDFNEVEAP KGAVISSGTE CFDLITNAID CFRLVFGAVG LGIMQGAFEE ALTYSQSRVA FGKPICSFQA VGFYLADM ALI: 45-273 AEMG VGGIIAPEQY GGSGLGWVGA CIAMEELSRV SSAVALAAGA TSFYFAYPIL VAGSEEQKEK YVTAAAYGEK TGTLALTEAG CGPDIAKIQT TAEVKGDSLV LKGSKMSVTN ADNVDYILVF ARMINDGQPG DYILVVVDSK SPGITLRKVP KMGMSAVSTC EIDFNEVEAP KGAVISSGTE CFDLITNAID CFRLVFGAVG LGIMQGAFEE ALTYSQSRVA FGKPI ENV: 22-371 EIKPVAG EIDEKEEYPS EILGKLAEMG VGGIIAPEQY GGSGLGWVGA CIAMEELSRV SSAVALAAGA TSFYFAYPIL VAGSEEQKEK YVTAAAYGEK TGTLALTEAG CGPDIAKIQT TAEVKGDSLV LKGSKMSVTN ADNVDYILVF ARMINDGQPG DYILVVVDSK SPGITLRKVP KMGMSAVSTC EIDFNEVEAP KGAVISSGTE CFDLITNAID CFRLVFGAVG LGIMQGAFEE ALTYSQSRVA FGKPICSFQA VGFYLADMFK MSRIARNMIY QAAFKADQGL DISLDAQVAK LFASESCMWV ADRALQIHGG YGFSIEYPIS RFFREARLME VGEGTSETLK ETI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380
Sequence: MDLSLNETQ QMYVNTVSRF VKNEILPHAL EMDRGHVFPV DMLKKIWEMG IMNISIPESI KGYNVDVVSA ALIIRELSYG DSGVATSAMC NDLANVVIAQ HGSQAQQEAY LKPFVDAPLV SAFCLTEPAA GSDNLSMTSF IAKRDDGKYV LNGSKCFITN ASYASQFTVF CKVGKPSSQL MACAIIPAIP VPLDSASPIK GVREIQLPTG GKIIVGKPED KLGQCLSNTA SVTFEDVILE PGQIIGDRRL GFKYVIDVLD FARPMIAAIG VGVAKRAFDL TLSYAKERKL FGQRLCDIPV ARQTLVSMWK KVELSELALL KSALKIMEDA PDKGIYSSLA KNCAAEAALF CCNEGLHLHG GYGFTNEYEI SKLVRDVHII DIYEGTREVQ DMIIGRELV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390
PF02771: 5-115 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF02770: 120-236 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦
PF00441: 249-397 ◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌
Sequence: MDLSLNETQ QMYVNTVSRF VKNEILPHAL EMDRGHVFPV DMLKKIWEMG IMNISIPESI KGYNVDVVSA ALIIRELSYG DSGVATSAMC NDLANVVIAQ HGSQAQQEAY LKPFVDAPLV SAFCLTEPAA GSDNLSMTSF IAKRDDGKYV LNGSKCFITN ASYASQFTVF CKVGKPSSQL MACAIIPAIP VPLDSASPIK GVREIQLPTG GKIIVGKPED KLGQCLSNTA SVTFEDVILE PGQIIGDRRL GFKYVIDVLD FARPMIAAIG VGVAKRAFDL TLSYAKERKL FGQRLCDIPV ARQTLVSMWK KVELSELALL KSALKIMEDA PDKGIYSSLA KNCAAEAALF CCNEGLHLHG GYGFTNEYEI SKLVRDVHII DIYEGTREVQ DMIIGRELV HMM: 29-193 EMDRGHVFPV DMLKKIWEMG IMNISIPESI KGYNVDVVSA ALIIRELSYG DSGVATSAMC NDLANVVIAQ HGSQAQQEAY LKPFVDAPLV SAFCLTEPAA GSDNLSMTSF IAKRDDGKYV LNGSKCFITN ASYASQFTVF CKVGKPSSQL MACAIIPAIP VPLDS ALI: 22-189 EILPHAL EMDRGHVFPV DMLKKIWEMG IMNISIPESI KGYNVDVVSA ALIIRELSYG DSGVATSAMC NDLANVVIAQ HGSQAQQEAY LKPFVDAPLV SAFCLTEPAA GSDNLSMTSF IAKRDDGKYV LNGSKCFITN ASYASQFTVF CKVGKPSSQL MACAIIPAIP V ENV: 6-203 ETQ QMYVNTVSRF VKNEILPHAL EMDRGHVFPV DMLKKIWEMG IMNISIPESI KGYNVDVVSA ALIIRELSYG DSGVATSAMC NDLANVVIAQ HGSQAQQEAY LKPFVDAPLV SAFCLTEPAA GSDNLSMTSF IAKRDDGKYV LNGSKCFITN ASYASQFTVF CKVGKPSSQL MACAIIPAIP VPLDSASPIK GVREI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF04879: 3-57 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
PF00384: 59-475 ✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
PF01568: 572-675 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 127-329 PN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR M ALI: 45-242 PRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTI ENV: 35-243 EHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 402-481 KSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDL ALI: 245-325 EELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIP ENV: 240-335 YTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 626-700 GSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI ALI: 401-478 FKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF ENV: 380-480 AIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 834-914 ALI: 561-641 TPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPG ENV: 551-655 YLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 75-312 SWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVT ALI: 16-241 CGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYT ENV: 1-244 ERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 386-463 NPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESK ALI: 244-321 FEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTW ENV: 240-325 YTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 610-684 HYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI ALI: 400-477 AFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLG ENV: 394-480 ANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 831-921 ALI: 561-651 TPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQ ENV: 552-662 LEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 90-309 IKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL Q ALI: 34-241 QEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYT ENV: 4-244 TVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 385-468 ANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI ALI: 245-328 EELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR ENV: 242-333 IGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 612-680 GVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IE ALI: 405-476 DFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRL ENV: 382-479 VAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MERKTVVSD CMSCVWDCGI KVTLEDGKMV KVEGLQEHPV TKGYICPRGE YLAEFVYSPD RIKYPMRRVG NTWERLSWEE ALDFAAEKLA AIKEKYGAKA LAIFCGSMGV ENIEVAGFAQ RFKSAYGTPN LLSVENICYR SRILARQMTF GRYPMDYPPD ARCIILWGHN PDGSKGMLAD MIREKIEKRE LDLIVIDPKR TQLSELGLHM AIRPGTDGAI GLAMLNVIIN EGLYDKEFVE KYTIGFEELK AHVQQYTPEW AAEITWAAAS DIKAIARIFA QSKPGCIVQG INTLDQHVNG LQLSRLLSIL QIVTGNIDKP GTWVTIPFLR MTDLRLPMDE VPIGADQYPL FYMLWGRKSP YGIATLFPQA ALEGKPYPVR GAIVAAANPA VSFPEANKFI EAFKSMDFLM AIDIVMTETA EMADLVLPAC TFMEKDALAY VYGVVHGEPF AMYHHKVIEP IGESKPDWWI WTELARRLGF GDLFPWNSDE EVMDHLLEPS GITEELKANP MGVYFDKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPDFKALLCK IESI HMM: 800-915 ALI: 544-662 GYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDV ENV: 514-671 DKQDY FAYENKKINT PSGKIEIYSK TLEEAGYDPL PKYLEPAQSP VSTPELAKEF PVILISGARR QAFTHTQMRH VPHLRALEPE PFAEMHPATA SHYGVKDGER IRLSTRNGSI TMRAKEEPRL LPGIVSVPHG WSQANVNLLT DMDVRDPITG YPD Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
PF00384: 11-344 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
PF01568: 425-532 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 227-330 GV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EA ALI: 3-107 LAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTEN ENV: 1-109 AGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF E Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 402-481 RGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRR ALI: 109-188 EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL ENV: 106-196 ENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 600-702 ALI: 250-348 IKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW ENV: 234-369 PGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK G Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 840-919 ALI: 422-502 QYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIP ENV: 410-512 TEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 211-314 LQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTE ALI: 3-107 LAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTEN ENV: 1-108 AGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 386-470 TLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IK ALI: 108-194 F EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNV ENV: 106-223 ENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 609-690 ALI: 272-351 HSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYV ENV: 266-378 DLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 837-916 ALI: 422-502 QYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIP ENV: 411-511 EYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 208-311 T AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYT ALI: 3-107 LAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTEN ENV: 1-127 AGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESIT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 432-462 ILYQYHT ATMSRRSQGL VSRTPEAFME INPA ALI: 156-186 TQH ITGTDAVKSL ANLAMLTGNI GRPGTGVN ENV: 108-196 F EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 609-681 ALI: 275-345 SKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMG ENV: 252-372 ALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITY Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MAGLAASFG SGAMTNSITD LIESDCFLIT GSNTTENHPV IASVVKRAIT QRGAKLILAD PRNIELAKFA TVWLRQKPGT DIAWINGLLN IIIAEDLLDK EFVAERTENF EALKLAVAKY TPEFVESITS IPGGDLVKAA HLYAKAGAAS ILYAMGITQH ITGTDAVKSL ANLAMLTGNI GRPGTGVNPL RGQNNVQGAC DMGCLPVNFT AYLQVANEEH RRKFEDAWGV SLNPKPGLTI PKIIEGADTG AIKALLIMGE NPMMSDPDLA HVEHSLSKLD LLVVQDIFLN ETGSLADVVL PACAWAEKEG TYTNTERRVQ RVRKAVNAPG EARDDWQILT MLANKMGADW KYVQAKAIME EINSVTASYK GITYERIADT GIQWPCPTLE HPGTPILHSA IFTRGRGLFS VTEYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIANIPEYK VCAVKIQKCS HMM: 820-899 ALI: 422-502 QYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIP ENV: 411-522 EYIPPAEQ TDDQYPFVLT TGRILYQYHT ATMSRRSQGL VSRTPEAFME INPADAGELG IKNGEKIEVS SRRGSITLRA DVRDRVDRGV VFIPFHYSEA AVNRLTITAI DPIA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF04879: 0-54 ♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF00384: 57-474 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦
PF01568: 573-670 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR HMM: 127-326 FF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIR ALI: 43-237 AKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDN ENV: 35-241 WLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR HMM: 402-479 LELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG D ALI: 243-321 DKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVT ENV: 238-331 W CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR HMM: 629-700 KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR ALI: 402-477 LELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGY ENV: 395-479 FLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG D Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR HMM: 106-310 VEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA IT ALI: 36-237 LNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDN ENV: 14-241 CGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR HMM: 386-463 ALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRP ALI: 242-319 FDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG W ENV: 238-324 W CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR HMM: 613-684 IIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDP ALI: 401-476 QLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLG ENV: 395-482 FLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR HMM: 829-921 ALI: 559-651 RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAA ENV: 551-656 HVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR HMM: 72-308 VSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ALI: 14-238 CGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW ENV: 5-242 TDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR HMM: 385-466 PALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWS ALI: 243-324 DKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQ ENV: 238-331 W CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR HMM: 611-680 YDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LV ALI: 402-475 LELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRL ENV: 378-478 F FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MEKIQTDCA LCINCCGLDC YVEDGKLVKV EGTPEHWLNK GALCAKAKFL VEGTYSPNRL KYPMKKVNGK FERVSWDQAL DEIAAKLKEL KEKYGAHTLA TWTGSVGVEH FEMAAFNQRF AKAYGSPNFF NPEGICFRTR ILARQITFGR YPVEQPRNAK LIILWGHNPD ASYFVIANDI RERVRKNELE LIVIDVRKIP LAKEGIYLQP RPGTDAAIAL AMMNVIINEG LYDKEFVDNW CTGFDKLTEH VKKLTPEWAE EVSGVPAPEI KRIARMFANV KEASILEGVG HLNQYQNGLQ NERCFNILMA ITGKIDRPGG WVTCPQIRLA DLRVPIEEKN LGYDEYPVFH QFNKRTPPYG SASMMTEAMI TGKPYPIKAF FSSGSNPALT FPDTGRFLDG LKQLELFVSI DPYMTETSEL ADYALPACTF LEETGIGGFP YAISHCVPYI ILRKKVIEPL YESRPIWSIW SELGRRLGYG DLFPWKTDEE VAEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DSRVRDKVSG YITMRGNACR LVKLDPSR HMM: 813-905 ALI: 560-652 ANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAA ENV: 490-660 AEHMFSTSG VTYQQLVDHP EGLYFGEIEY ELFKRVGFAT ASGKVELYSA EMERLGAPGL PSHVEPEQSY RANPEIAKKY PETLLTGARH QEFIGAQMKD VSGLMALLPE PHAMIHPVTA KKYDIIEGEL MGVETPRGMI KIKANVTEDI RPGAVSIPHG WAAANVNILL DS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
PF04879: 10-51 ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦
PF00384: 63-509 ✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦
PF01568: 614-730 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 141-329 CFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA L ALI: 63-249 RLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT F ENV: 11-250 NCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 402-439 FRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK A ALI: 252-288 DRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ ENV: 248-327 T FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 604-679 DWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF A ALI: 417-492 IV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVP ENV: 397-510 HG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 842-919 ALI: 609-686 PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAA ENV: 590-695 DPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 71-312 VGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAI ALI: 16-248 TSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT ENV: 5-250 VELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 387-463 PA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPA ALI: 252-328 DRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA ENV: 249-338 FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 607-653 RY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGI ALI: 433-479 VYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI G ENV: 417-519 IV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE K Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 839-920 ALI: 609-690 PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WW ENV: 593-708 PDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 65-310 SYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IR ALI: 11-249 NCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT F ENV: 2-251 RSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 385-467 HHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWL ALI: 252-335 DRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYE ENV: 248-357 T FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQ Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 585-653 EKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGI ALI: 415-482 GLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYP ENV: 367-502 SY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MDRSDVELK YSNCYFCTSR GCAMKVYVKG DRVERVRIDR SAPVNPGGWC VRPFLAKEYQ EHPFRLSYPL KRVGERGANS WQQISWDQAL DEIARKLETI RQQYGAEALA TSSGTGRGAW DFAKGRFMNL FGSPNRFGAV TVCFGPRSMV SFSMYGGSLV PDRKPDKTRL VVLWGREPHE GGAHTWHGFQ QAIRDGARTM VVDPRFTEPA RRADIWVQLR PGTGTPLALG MMHLMIAEGW HNKAFVEAHT FGFDRLAERV KAYPPERVAA LTGISVPRLR EITRFFTENQ PATVTIGCAP EHSAPNSIND IRAINILFAI AGSIDVAGGA LIGGPYEDFI PDAALEANEA LSPEQRRKQL GSDRFRFLSY PGWELVVEQL RKKWGNHHPA AVYLNCMAHG PTAFRAMLTG KPYPVRGLIV SASNPLLSFA NSKLVYRALK ALDLLVTLDI TWTPTAQLSD YVLPAACWLE RPDMGNFASI GSYPLVQIGE AAVPASVPGS YDRRNDYEFW RGLGVRLGQE KDWPWETFEA VWEYRLQGMM KKEGVETLAE LVHKQRWAVT PPQPGLCAAG PLATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PSLYGLWESN INVTIDDDLE KCDPVSGGWP LKGEYVRCRI SKAAEGEEPF HMM: 821-904 ALI: 608-691 Y PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWY ENV: 570-700 LATPTGKVE LYSTILEKLG YDPLPDYQEP LPPDGDWSRY PLLNISGTRV LPYHHTEFRH VEGFRKRQPF PIVEIHVDTA RRHGIVDGDW VWIESPLGRV KQRARLVNTF APDCIVAAHG WWYPEKPAAE PS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
PF00384: 56-471 ✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
PF01568: 574-676 ✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 125-329 PNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN I ALI: 40-240 SCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TT ENV: 35-242 PEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 400-479 FAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF P ALI: 241-320 GFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VL ENV: 238-332 Y TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 603-700 EDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ ALI: 379-474 VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGF ENV: 359-479 QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF P Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 873-917 ALI: 597-641 VV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIR ENV: 575-656 DIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 110-312 APWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNL ALI: 41-239 CPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY T ENV: 35-241 PEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 385-463 NPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWR ALI: 241-318 GFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD ENV: 238-321 Y TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLP Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 610-684 LKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQ ALI: 399-473 AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLG ENV: 378-487 M VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 873-920 ALI: 600-647 IHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWG ENV: 590-654 LNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 108-310 W GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TG ALI: 42-240 PKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TT ENV: 33-243 LAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 385-464 NPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRI ALI: 243-322 EQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQ ENV: 238-331 Y TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 592-680 AGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RL ALI: 385-472 NPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRL ENV: 366-478 DAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MILDSVCRL CSSCCPIEVE VVDERLIAAR RKSFLAPEKR LSCPKLAAAP DIVYSPLRLT TPLIKKDDGS GFRKAGWDEA LDRVVTRFLR HREEYGAQSV AWLRGMAADW GAPWDYPNRL MHLFGSPNTI GNGSICFVAR EFAHSYTYGA MAFPEAKNAR CIIVWGKNDG NTALGAAEAI SYAKEQGATL IVIDPVQTAL ARKADLWLQI KPGHDGLLAM AMISQIIEEK LYDAEFVEKY TTGFEQLKEV AARYPAEAVA EKIWLSADQI RDLARLYATT KPSSIIDGNG LDMHREVFDT TRAIAMLRAL TGNLDRPGGD VLPQPIPLRN IQLKDRLPAG VVPITRDYPL FNAFSETWGN QVQGCLIDAI LAEQPYPVKM VVVQTGNPVV TMADSTRTRE AFAKLETLVV IEMFMTETAK LADVILPAAS CFETTQLNRF SIRNNPMFLQ NAVIPPVGDS WPNWRIVFEL GRRLGFVTEF PWQSAEEAID YQLEPAGVTV EKLRRNGSGL RIEELRYEKY REAPFKTPSG RVEFFSRRLA EAGLPGVPFS EGLGGDPISF ADQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGRVT GTSTSRSFMC RLRKVQQQ HMM: 837-917 ALI: 582-659 QFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL T ENV: 560-666 DQSEAYPIL GISGSRDIRF TNSQFRTIPS LLNAGAGCVV DIHPEDARRY DLKENDPVRI ESPKGSIEMA ARISTTVRPG TIRLSWGWGE HDLRGNLNTL TEDDRRGR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESNV QGSTDHGLLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANYSWLNLF DQMYKGKFTG FFAWGMNPAC SGAHSNKVRQ AMAKLDWVVN VNLFDNETGS FWRGPGMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK TFSGHFHFDP HAVAKEINGF FLEDKTVENP TKKGEMKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYAD KGNMSARRDG KKDPTGIGLY PEWAWAWPVN RRIIYNGASV DPTGKPWSAK KTVIKWTGDK WVGDVPDGVG DPGSGRPPFI MKPDGVASLF GPGLADGPFP EHYEPLECPV EKNLLSPQKS NPTIKRFDKP GVGSDMDKYS GIDSCDPKYP FICATYRISE HWQTGLQTRW CPWLSEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNINGNIL HEVGIPWHFG WITTKDRPYN PGDKKAEVFT KGDAANLLVP TIGDANTTIP ESKAFMVNVV KK
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
PF00384: 1-373 ✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦
PF01568: 690-822 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESNV QGSTDHGLLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANYSWLNLF DQMYKGKFTG FFAWGMNPAC SGAHSNKVRQ AMAKLDWVVN VNLFDNETGS FWRGPGMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK TFSGHFHFDP HAVAKEINGF FLEDKTVENP TKKGEMKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYAD KGNMSARRDG KKDPTGIGLY PEWAWAWPVN RRIIYNGASV DPTGKPWSAK KTVIKWTGDK WVGDVPDGVG DPGSGRPPFI MKPDGVASLF GPGLADGPFP EHYEPLECPV EKNLLSPQKS NPTIKRFDKP GVGSDMDKYS GIDSCDPKYP FICATYRISE HWQTGLQTRW CPWLSEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNINGNIL HEVGIPWHFG WITTKDRPYN PGDKKAEVFT KGDAANLLVP TIGDANTTIP ESKAFMVNVV KK HMM: 246-482 LLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANYSWLNLF DQMYKGKFTG FFAWGMNPAC SGAHSNKVRQ AMAKLDWVVN VNLFDNETGS FWRGPGMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK TFSGHFHFDP HAVA ALI: 10-233 SDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMR ENV: 6-249 DIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESNV QGSTDHGLLF H Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESNV QGSTDHGLLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANYSWLNLF DQMYKGKFTG FFAWGMNPAC SGAHSNKVRQ AMAKLDWVVN VNLFDNETGS FWRGPGMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK TFSGHFHFDP HAVAKEINGF FLEDKTVENP TKKGEMKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYAD KGNMSARRDG KKDPTGIGLY PEWAWAWPVN RRIIYNGASV DPTGKPWSAK KTVIKWTGDK WVGDVPDGVG DPGSGRPPFI MKPDGVASLF GPGLADGPFP EHYEPLECPV EKNLLSPQKS NPTIKRFDKP GVGSDMDKYS GIDSCDPKYP FICATYRISE HWQTGLQTRW CPWLSEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNINGNIL HEVGIPWHFG WITTKDRPYN PGDKKAEVFT KGDAANLLVP TIGDANTTIP ESKAFMVNVV KK HMM: 868-911 ALI: 713-758 SEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF ENV: 687-763 YP FICATYRISE HWQTGLQTRW CPWLSEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESNV QGSTDHGLLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANYSWLNLF DQMYKGKFTG FFAWGMNPAC SGAHSNKVRQ AMAKLDWVVN VNLFDNETGS FWRGPGMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK TFSGHFHFDP HAVAKEINGF FLEDKTVENP TKKGEMKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYAD KGNMSARRDG KKDPTGIGLY PEWAWAWPVN RRIIYNGASV DPTGKPWSAK KTVIKWTGDK WVGDVPDGVG DPGSGRPPFI MKPDGVASLF GPGLADGPFP EHYEPLECPV EKNLLSPQKS NPTIKRFDKP GVGSDMDKYS GIDSCDPKYP FICATYRISE HWQTGLQTRW CPWLSEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNINGNIL HEVGIPWHFG WITTKDRPYN PGDKKAEVFT KGDAANLLVP TIGDANTTIP ESKAFMVNVV KK HMM: 230-322 QAMRGESNV QGSTDHGLLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANY ALI: 10-102 SDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDF ENV: 3-106 HWIDIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESNV QGSTDHGLLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANYSWLNLF DQMYKGKFTG FFAWGMNPAC SGAHSNKVRQ AMAKLDWVVN VNLFDNETGS FWRGPGMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK TFSGHFHFDP HAVAKEINGF FLEDKTVENP TKKGEMKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYAD KGNMSARRDG KKDPTGIGLY PEWAWAWPVN RRIIYNGASV DPTGKPWSAK KTVIKWTGDK WVGDVPDGVG DPGSGRPPFI MKPDGVASLF GPGLADGPFP EHYEPLECPV EKNLLSPQKS NPTIKRFDKP GVGSDMDKYS GIDSCDPKYP FICATYRISE HWQTGLQTRW CPWLSEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNINGNIL HEVGIPWHFG WITTKDRPYN PGDKKAEVFT KGDAANLLVP TIGDANTTIP ESKAFMVNVV KK HMM: 384-469 GMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK T ALI: 146-234 CVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRG ENV: 137-250 KD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESNV QGSTDHGLLF HI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESNV QGSTDHGLLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANYSWLNLF DQMYKGKFTG FFAWGMNPAC SGAHSNKVRQ AMAKLDWVVN VNLFDNETGS FWRGPGMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK TFSGHFHFDP HAVAKEINGF FLEDKTVENP TKKGEMKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYAD KGNMSARRDG KKDPTGIGLY PEWAWAWPVN RRIIYNGASV DPTGKPWSAK KTVIKWTGDK WVGDVPDGVG DPGSGRPPFI MKPDGVASLF GPGLADGPFP EHYEPLECPV EKNLLSPQKS NPTIKRFDKP GVGSDMDKYS GIDSCDPKYP FICATYRISE HWQTGLQTRW CPWLSEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNINGNIL HEVGIPWHFG WITTKDRPYN PGDKKAEVFT KGDAANLLVP TIGDANTTIP ESKAFMVNVV KK HMM: 636-694 PFP EHYEPLECPV EKNLLSPQKS NPTIKRFDKP GVGSDMDKYS GIDSCDPKYP FICATY ALI: 398-454 P CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPH ENV: 395-475 FMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK TFSGHFH Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESNV QGSTDHGLLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANYSWLNLF DQMYKGKFTG FFAWGMNPAC SGAHSNKVRQ AMAKLDWVVN VNLFDNETGS FWRGPGMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK TFSGHFHFDP HAVAKEINGF FLEDKTVENP TKKGEMKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYAD KGNMSARRDG KKDPTGIGLY PEWAWAWPVN RRIIYNGASV DPTGKPWSAK KTVIKWTGDK WVGDVPDGVG DPGSGRPPFI MKPDGVASLF GPGLADGPFP EHYEPLECPV EKNLLSPQKS NPTIKRFDKP GVGSDMDKYS GIDSCDPKYP FICATYRISE HWQTGLQTRW CPWLSEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNINGNIL HEVGIPWHFG WITTKDRPYN PGDKKAEVFT KGDAANLLVP TIGDANTTIP ESKAFMVNVV KK HMM: 874-911 ALI: 724-761 SKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPF ENV: 717-764 PE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNIN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESNV QGSTDHGLLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANYSWLNLF DQMYKGKFTG FFAWGMNPAC SGAHSNKVRQ AMAKLDWVVN VNLFDNETGS FWRGPGMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK TFSGHFHFDP HAVAKEINGF FLEDKTVENP TKKGEMKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYAD KGNMSARRDG KKDPTGIGLY PEWAWAWPVN RRIIYNGASV DPTGKPWSAK KTVIKWTGDK WVGDVPDGVG DPGSGRPPFI MKPDGVASLF GPGLADGPFP EHYEPLECPV EKNLLSPQKS NPTIKRFDKP GVGSDMDKYS GIDSCDPKYP FICATYRISE HWQTGLQTRW CPWLSEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNINGNIL HEVGIPWHFG WITTKDRPYN PGDKKAEVFT KGDAANLLVP TIGDANTTIP ESKAFMVNVV KK HMM: 226-464 GGG VQAMRGESNV QGSTDHGLLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANYSWLNLF DQMYKGKFTG FFAWGMNPAC SGAHSNKVRQ AMAKLDWVVN VNLFDNETGS FWRGPGMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWN ALI: 9-232 NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAM ENV: 4-237 WIDIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MTNHWIDIR NSDVILIMGS NPASNHPVAF KWITAAMEKG AKVICVDPRF TQSAAKSHVY APLRSGTDIA FLGGMIKYII ENKLYFEEYV KNYTNASFLV NPDFKLPGDN NGVFSGLTDG KYDKATWSYQ TEGDGLIKKD PTLQDPNCVF QLLKKHYSRY TPEIVNKITG TPVDKLIEVY KLYGSTGTPD RAGNELYAMG WTQHTIGTQN IRTMCIIQLL LGNMGIPGGG VQAMRGESNV QGSTDHGLLF HIWPGYLSTP KASLATLAAY NEKETPTTKE PNSLNWQKNK PKYVASFLRA MYGTNATLDE AYNLLPKIDD GANYSWLNLF DQMYKGKFTG FFAWGMNPAC SGAHSNKVRQ AMAKLDWVVN VNLFDNETGS FWRGPGMDPK KIKTEVFMLP CCASIEKEGS IINSGRWNQW RYKAVDAPGV ALPDGDITSE IYFKVKELYE KEGGPHKEAL TKLTWNYGTK TFSGHFHFDP HAVAKEINGF FLEDKTVENP TKKGEMKEFK KGDPVPTFAW LQDDGSTSSG CWVYCGSYAD KGNMSARRDG KKDPTGIGLY PEWAWAWPVN RRIIYNGASV DPTGKPWSAK KTVIKWTGDK WVGDVPDGVG DPGSGRPPFI MKPDGVASLF GPGLADGPFP EHYEPLECPV EKNLLSPQKS NPTIKRFDKP GVGSDMDKYS GIDSCDPKYP FICATYRISE HWQTGLQTRW CPWLSEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNINGNIL HEVGIPWHFG WITTKDRPYN PGDKKAEVFT KGDAANLLVP TIGDANTTIP ESKAFMVNVV KK HMM: 849-894 ALI: 716-761 QPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPF ENV: 682-771 SCDPKYP FICATYRISE HWQTGLQTRW CPWLSEMQPE MWCEMSKELA KERGIANGDI VIVSSPRGQV ECVAIVTPRF KPFNINGNIL HEV Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830
Sequence: MDHEHNIPR RDFLKIAGAL GIGASASLFP FRNLRQAWAF GEHPQEKPSY TIKKKVPQVC ARACEADCAY YVVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWLEELAP PVVPFPEQPA EPVDFRNEFP VTNEIYLKKD FSAPGHYGMV GWGLYKTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWIDNKPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850
PF00384: 220-578 ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MDHEHNIPR RDFLKIAGAL GIGASASLFP FRNLRQAWAF GEHPQEKPSY TIKKKVPQVC ARACEADCAY YVVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWLEELAP PVVPFPEQPA EPVDFRNEFP VTNEIYLKKD FSAPGHYGMV GWGLYKTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWIDNKPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA HMM: 127-151 KG TDEDPGWITM KTGDAVNEVI AGL ALI: 101-125 IKGLGFVD SVYDPDRLMV SLKRTNP ENV: 98-155 K FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850
Sequence: MDHEHNIPR RDFLKIAGAL GIGASASLFP FRNLRQAWAF GEHPQEKPSY TIKKKVPQVC ARACEADCAY YVVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWLEELAP PVVPFPEQPA EPVDFRNEFP VTNEIYLKKD FSAPGHYGMV GWGLYKTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWIDNKPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA HMM: 271-444 GYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTG ALI: 252-414 KKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFI ENV: 238-451 K CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850
Sequence: MDHEHNIPR RDFLKIAGAL GIGASASLFP FRNLRQAWAF GEHPQEKPSY TIKKKVPQVC ARACEADCAY YVVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWLEELAP PVVPFPEQPA EPVDFRNEFP VTNEIYLKKD FSAPGHYGMV GWGLYKTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWIDNKPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA HMM: 621-663 YWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWI ALI: 538-580 M LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DT ENV: 514-612 KTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850
Sequence: MDHEHNIPR RDFLKIAGAL GIGASASLFP FRNLRQAWAF GEHPQEKPSY TIKKKVPQVC ARACEADCAY YVVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWLEELAP PVVPFPEQPA EPVDFRNEFP VTNEIYLKKD FSAPGHYGMV GWGLYKTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWIDNKPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA HMM: 858-900 A ALI: 734-778 FINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY ENV: 666-811 KPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHR Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850
Sequence: MDHEHNIPR RDFLKIAGAL GIGASASLFP FRNLRQAWAF GEHPQEKPSY TIKKKVPQVC ARACEADCAY YVVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWLEELAP PVVPFPEQPA EPVDFRNEFP VTNEIYLKKD FSAPGHYGMV GWGLYKTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWIDNKPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA HMM: 107-462 VD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPW ALI: 97-451 GK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGG ENV: 86-458 LEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850
Sequence: MDHEHNIPR RDFLKIAGAL GIGASASLFP FRNLRQAWAF GEHPQEKPSY TIKKKVPQVC ARACEADCAY YVVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWLEELAP PVVPFPEQPA EPVDFRNEFP VTNEIYLKKD FSAPGHYGMV GWGLYKTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWIDNKPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA HMM: 606-658 WGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK ALI: 538-592 M LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFG ENV: 526-609 PHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS F Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850
Sequence: MDHEHNIPR RDFLKIAGAL GIGASASLFP FRNLRQAWAF GEHPQEKPSY TIKKKVPQVC ARACEADCAY YVVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWLEELAP PVVPFPEQPA EPVDFRNEFP VTNEIYLKKD FSAPGHYGMV GWGLYKTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWIDNKPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA HMM: 795-896 RVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA ALI: 672-777 KTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPN ENV: 666-787 KPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850
Sequence: MDHEHNIPR RDFLKIAGAL GIGASASLFP FRNLRQAWAF GEHPQEKPSY TIKKKVPQVC ARACEADCAY YVVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWLEELAP PVVPFPEQPA EPVDFRNEFP VTNEIYLKKD FSAPGHYGMV GWGLYKTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWIDNKPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA HMM: 101-134 IKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPG ALI: 94-127 VSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKK ENV: 70-163 VVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFAS Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850
Sequence: MDHEHNIPR RDFLKIAGAL GIGASASLFP FRNLRQAWAF GEHPQEKPSY TIKKKVPQVC ARACEADCAY YVVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWLEELAP PVVPFPEQPA EPVDFRNEFP VTNEIYLKKD FSAPGHYGMV GWGLYKTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWIDNKPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA HMM: 233-460 FDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KI ALI: 230-452 WFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGV ENV: 208-463 M STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850
Sequence: MDHEHNIPR RDFLKIAGAL GIGASASLFP FRNLRQAWAF GEHPQEKPSY TIKKKVPQVC ARACEADCAY YVVMGVDPAT GLERAITLEG RPEDPVSRGK FCIKGLGFVD SVYDPDRLMV SLKRTNPKKG TDEDPGWITM KTGDAVNEVI AGLKKVKPQE ILFASPGDPY TNRLCQSIGA TRSDQRTECF GTHYYINCLT LTNPPNKYYM STYTPSHHVA GYDYDTAKYQ VWFGFDSFSK CGKAGMLNHW AAGKKNGAKI VVFNPVRTPL CDGYASEFHA IKPGTDLAVA LAMLQVITSG KKYNMDFLRK YSDAAALVDV KTKMTLKDEK GSFLAWCAKH KKAEPIDDCH EPALGGGPFK VVVEGKEISA RPVIGLLAEE IKTYTPEWAA KISEVPAKSI RKIALEFAAA APQSFIPTYK RDAAGPNYAN SWRLRHAISV LNALTGAIDH EGGVILLHGL KIPWLEELAP PVVPFPEQPA EPVDFRNEFP VTNEIYLKKD FSAPGHYGMV GWGLYKTNRA KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRLYYPKNP CLFGGAPIQK PPGDQIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIKNVGA GENTADFMKK GAFWIDNKPY ENYKTLREIG YGRPQGRIRM YIDEFVPVGH EPLPKWAPRW HASTDPYKFS LLITRAPWHM HADPNFINNA VLKEVTVRNH MDCVWINPEA GKKLGLKEGD MVILENDPNY VKDLPRPQKA KIHLTNRVAR QDCILTFHGI GHRAKNLRTA KDFGYRDGDL IPQKDPNIVK KHDPTGMGWV EDVYVSIRKA HMM: 603-644 QIGWGS FAAAIGMAMA PKYWTTDGSG DPAKKIPTNI GDVAIK ALI: 538-579 M LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL D ENV: 518-582 A KVVFFRNPHR GLFAMIQPQM LEKATEKMDM VVDWNLYLDD LGYFCDYVIP APHQFEEGKL DTRL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820 830 840 850
Sequence: MGTVTLKDI RIADMNLETL PLLSSLKEQC LSAKAEVCIE RAKHITTFLR DRADESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLKT GKAAHFPEEH KGMLPST
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820
PF02901: 22-672 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF01228: 687-788 ✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦
Sequence: MGTVTLKDI RIADMNLETL PLLSSLKEQC LSAKAEVCIE RAKHITTFLR DRADESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLKT GKAAHFPEEH KGMLPST HMM: 35-821 VCIE RAKHITTFLR DRADESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLKT GKAAHFPEEH KGM ALI: 33-807 AEVCIE RAKHITTFLR DRADESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLK ENV: 27-808 QC LSAKAEVCIE RAKHITTFLR DRADESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLKT Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820
Sequence: MGTVTLKDI RIADMNLETL PLLSSLKEQC LSAKAEVCIE RAKHITTFLR DRADESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLKT GKAAHFPEEH KGMLPST HMM: 53-831 ESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLKT GKAAHFPEEH KGMLPST ALI: 34-805 EVCIE RAKHITTFLR DRADESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYD ENV: 25-807 KEQC LSAKAEVCIE RAKHITTFLR DRADESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLK Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820
Sequence: MGTVTLKDI RIADMNLETL PLLSSLKEQC LSAKAEVCIE RAKHITTFLR DRADESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLKT GKAAHFPEEH KGMLPST HMM: 66-853 NYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLKT GKAAHFPEEH KGMLPST ALI: 34-810 EVCIE RAKHITTFLR DRADESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLKT GK ENV: 26-817 EQC LSAKAEVCIE RAKHITTFLR DRADESEPME MRYARAVNYF LANKRSLFSD DSLLAGTTTA KAFGAPVYPE LTGIYIWPEL DTMTNREKNP QILSRTDADE LNFNIFPYWM ERNILEATRA REGNPPCMKL FERTVFFIAS KAGTISHTVP CYRVALEKGL EAIIAEAAQK EQRLAGKGSL SPDEAQQRDF YRAVQIALSG IITYAANLSA RAAELARQET DPVRRKNLEA MASVCAQVPA KPARTFREAV NGLWILQIGI HAENINMAMS PGRLDQILYP WYSRDMADGK LTLKEAMELV GCLWLKLNDN TNLVPETSEE LFGGAGTVPA VTVGGIDEEG EDAVNDLTYI MLRITELLKT RDPSLNARYY MGKNSVAYRD RVAEVIANTR AVPAFYNDIA AIRTLENQGI ATKDARDYAI IGCVELSASG RSYDASSSIM LNLVSALELA LYNGTRPVTE EEQIGPATGV AESFQTFEAF WEAFKTQLGC LIGEAVQLNE MMGKTHQEIL PTPLLSALFE GPMEKGTDLI FGGARYNSSG ATHIGFADTV DSLNAIEKGV FIDRRVTFPE LIAALKRDFE GDAALHAYLV NRVPKYGSED PIAVKNSHNL LRFLYETYQG YTNYRGGKYR PAYWTMTNHA GQGKLSGALP NGRRAYRIFA SGITPVSQAA GELAACLNAV GDINVLHIPG GEAFNLKYSA IQGEEDLQKF SAAIEAYFRS GGLHIQFNIM SYEMLLDAKA HPDNYPELLV RVSGYSAYFK DLNEAMKDEI ITRTAYDLKT GKAAHFPEE Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400 410 420 430 440 450 460 470 480 490 500 510 520 530 540 550 560 570 580 590 600 610 620 630 640 650 660 670 680 690 700 710 720 730 740 750 760 770 780 790 800 810 820
Sequence: MKITIDGRE IEFNPGQTVY QIAKSAGIYI PVLCHQEQVK PVGACRICMV EVEGARSLMA ACSLPASNGM VVSTNTERVL NVRRIIVEML MTQGHHNCIT CESSGNCVLQ DLAYELGMEA PRFDEPSSML ASETGNEMIV RDMNKCVLCG LCVRACNEIQ VNLVLDYTGR GSYSKVGPPF GLRYEESDCV FCGECVRVCP VGALYEKQGR FRGRFKDLTK VRTTCSYCGV GCQMDVCTKD DKIIKVTTDR EGMPAPNFGS LCIKGRFGYD YMQHPDRLTK PLIRRDGELK ETTWDEAIAF VAEKLRSIKE EHGADAIAGL ASARCTNEEN YIFQKFLRAV VGTNNVDHCA RL
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
PF13510: 1-75 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌
PF10588: 81-120 ◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌
PF00037: 183-204 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦
PF04879: 217-272 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦
PF00384: 275-351 ✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦
Sequence: MKITIDGRE IEFNPGQTVY QIAKSAGIYI PVLCHQEQVK PVGACRICMV EVEGARSLMA ACSLPASNGM VVSTNTERVL NVRRIIVEML MTQGHHNCIT CESSGNCVLQ DLAYELGMEA PRFDEPSSML ASETGNEMIV RDMNKCVLCG LCVRACNEIQ VNLVLDYTGR GSYSKVGPPF GLRYEESDCV FCGECVRVCP VGALYEKQGR FRGRFKDLTK VRTTCSYCGV GCQMDVCTKD DKIIKVTTDR EGMPAPNFGS LCIKGRFGYD YMQHPDRLTK PLIRRDGELK ETTWDEAIAF VAEKLRSIKE EHGADAIAGL ASARCTNEEN YIFQKFLRAV VGTNNVDHCA RL HMM: 109-170 DLAYELGMEA PRFDEPSSML ASETGNEMIV RDMNKCVLCG LCVRACNEIQ VNLVLDYTGR GS ALI: 259-316 LCIKGRFGYD YMQHPDRLTK PLIRRDGELK ETTWDEAIAF VAEKLRSIKE EHGADAIA ENV: 210-347 RGRFKDLTK VRTTCSYCGV GCQMDVCTKD DKIIKVTTDR EGMPAPNFGS LCIKGRFGYD YMQHPDRLTK PLIRRDGELK ETTWDEAIAF VAEKLRSIKE EHGADAIAGL ASARCTNEEN YIFQKFLRAV VGTNNVDHC Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350
Sequence: MDVSRRGFL KIAGGTLAAG GIGFRPSLAH AEPLKIQYGK ETTTICPYCS VGCSIIVTTR KGKVINTEGD PDSPINRGSL CTKGGSIYQL SANENRLGKP LYRAPYATEW KEVDWEWTLE RIAENIKKSR DKSFRATNDK GEVVNRTEGI ASVGSAAIDN EECFVHQKFL RGLGLVYIEH QARI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180
PF04879: 38-89 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MDVSRRGFL KIAGGTLAAG GIGFRPSLAH AEPLKIQYGK ETTTICPYCS VGCSIIVTTR KGKVINTEGD PDSPINRGSL CTKGGSIYQL SANENRLGKP LYRAPYATEW KEVDWEWTLE RIAENIKKSR DKSFRATNDK GEVVNRTEGI ASVGSAAIDN EECFVHQKFL RGLGLVYIEH QARI HMM: 5-22 RGFL KIAGGTLAAG GIGF ALI: 2-19 VSRRGFL KIAGGTLAAG G ENV: 1-43 DVSRRGFL KIAGGTLAAG GIGFRPSLAH AEPLKIQYGK ETTTI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180
Sequence: MDVSRRGFL KIAGGTLAAG GIGFRPSLAH AEPLKIQYGK ETTTICPYCS VGCSIIVTTR KGKVINTEGD PDSPINRGSL CTKGGSIYQL SANENRLGKP LYRAPYATEW KEVDWEWTLE RIAENIKKSR DKSFRATNDK GEVVNRTEGI ASVGSAAIDN EECFVHQKFL RGLGLVYIEH QARI HMM: 100-161 YRAPYATEW KEVDWEWTLE RIAENIKKSR DKSFRATNDK GEVVNRTEGI ASVGSAAIDN EEC ALI: 69-128 PDSPINRGSL CTKGGSIYQL SANENRLGKP LYRAPYATEW KEVDWEWTLE RIAENIKKSR ENV: 34-172 IQYGK ETTTICPYCS VGCSIIVTTR KGKVINTEGD PDSPINRGSL CTKGGSIYQL SANENRLGKP LYRAPYATEW KEVDWEWTLE RIAENIKKSR DKSFRATNDK GEVVNRTEGI ASVGSAAIDN EECFVHQKFL RGLG Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180
Sequence: MDITRRGFL HLSGAVGSGI ALSTLGINLK PARAYADELN KMNRVKAAKQ VTTVCAYCSC GCGLVCSVDK MTGKIFNIEG DADHPINEGT LCAKGAGFFD LTEANKHRLT KVLYRAPYAT EWEEKSWDFA IPRIARLIKD TRDKEFIAKN AKGELVNRCE SIGHYGSSNV DNEECWLMTV KSRALGMVYI DHQARV
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
PF04879: 47-97 ♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦
Sequence: MDITRRGFL HLSGAVGSGI ALSTLGINLK PARAYADELN KMNRVKAAKQ VTTVCAYCSC GCGLVCSVDK MTGKIFNIEG DADHPINEGT LCAKGAGFFD LTEANKHRLT KVLYRAPYAT EWEEKSWDFA IPRIARLIKD TRDKEFIAKN AKGELVNRCE SIGHYGSSNV DNEECWLMTV KSRALGMVYI DHQARV HMM: 5-162 RGFL HLSGAVGSGI ALSTLGINLK PARAYADELN KMNRVKAAKQ VTTVCAYCSC GCGLVCSVDK MTGKIFNIEG DADHPINEGT LCAKGAGFFD LTEANKHRLT KVLYRAPYAT EWEEKSWDFA IPRIARLIKD TRDKEFIAKN AKGELVNRCE SIGH ALI: 2-141 ITRRGFL HLSGAVGSGI ALSTLGINLK PARAYADELN KMNRVKAAKQ VTTVCAYCSC GCGLVCSVDK MTGKIFNIEG DADHPINEGT LCAKGAGFFD LTEANKHRLT KVLYRAPYAT EWEEKSWDFA IPRIARLIKD TRD ENV: 1-148 DITRRGFL HLSGAVGSGI ALSTLGINLK PARAYADELN KMNRVKAAKQ VTTVCAYCSC GCGLVCSVDK MTGKIFNIEG DADHPINEGT LCAKGAGFFD LTEANKHRLT KVLYRAPYAT EWEEKSWDFA IPRIARLIKD TRDKEFIAKN Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190
Sequence: METYKCTNC NHFYNPERGD KKHGIPAGTA FKDIPNDWRC PGCGSDKSKY KLDKPRPFPG YGPTFEKKD
10 20 30 40 50 60
PF00301: 3-49 ♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: METYKCTNC NHFYNPERGD KKHGIPAGTA FKDIPNDWRC PGCGSDKSKY KLDKPRPFPG YGPTFEKKD HMM: 424-469 ALI: 2-47 TYKCTNC NHFYNPERGD KKHGIPAGTA FKDIPNDWRC PGCGSDKSK ENV: 1-56 ETYKCTNC NHFYNPERGD KKHGIPAGTA FKDIPNDWRC PGCGSDKSKY KLDKPRPF Position: 10 20 30 40 50 60
Sequence: METTMDRKA LYDITYGLYV VTSIADGKMN GQIANTVFQI SSSPAKIAVS INKENLTHEY ILKSGILAVS ILEQETPLSF IGLFGFKSGR EIDKLCQCAY TPGVTGCPCV TDHALSYMEG KVVASADGGT HTVFVVELVA AAVLKKGAPL TYAYYQEVKN GKAPKTAPTY KGETAEPAVE IKKQERTMKK YECGICGYIY DPEIGDPENS IPAGTAFDQL PDDWTCPVCG AGKSEFSEVA
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230
PF01613: 12-152 ✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦✦✦✦✦✦✦✦ ✦✦✦
PF00301: 188-235 ♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦
Sequence: METTMDRKA LYDITYGLYV VTSIADGKMN GQIANTVFQI SSSPAKIAVS INKENLTHEY ILKSGILAVS ILEQETPLSF IGLFGFKSGR EIDKLCQCAY TPGVTGCPCV TDHALSYMEG KVVASADGGT HTVFVVELVA AAVLKKGAPL TYAYYQEVKN GKAPKTAPTY KGETAEPAVE IKKQERTMKK YECGICGYIY DPEIGDPENS IPAGTAFDQL PDDWTCPVCG AGKSEFSEVA HMM: 357-468 ALI: 116-232 MEG KVVASADGGT HTVFVVELVA AAVLKKGAPL TYAYYQEVKN GKAPKTAPTY KGETAEPAVE IKKQERTMKK YECGICGYIY DPEIGDPENS IPAGTAFDQL PDDWTCPVCG AGKS ENV: 109-239 TDHALSYMEG KVVASADGGT HTVFVVELVA AAVLKKGAPL TYAYYQEVKN GKAPKTAPTY KGETAEPAVE IKKQERTMKK YECGICGYIY DPEIGDPENS IPAGTAFDQL PDDWTCPVCG AGKSEFSEVA Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230
Sequence: MDKKRQQYR CAICGYIYDP ENGGRIGSIP AGTAFEDLPD EWTCPICGSD KSQFKPTISR PMYQPPK
10 20 30 40 50 60
PF00301: 6-53 ♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦
Sequence: MDKKRQQYR CAICGYIYDP ENGGRIGSIP AGTAFEDLPD EWTCPICGSD KSQFKPTISR PMYQPPK HMM: 421-475 ALI: 3-56 KRQQYR CAICGYIYDP ENGGRIGSIP AGTAFEDLPD EWTCPICGSD KSQFKPTI ENV: 1-63 DKKRQQYR CAICGYIYDP ENGGRIGSIP AGTAFEDLPD EWTCPICGSD KSQFKPTISR PMYQP Position: 10 20 30 40 50 60
Sequence: MDKYFCTGC GYIYDPRLGD PDNGVPRGTP FEELPEDWRC PICTAPESKF LPDHYEE
10 20 30 40 50
PF00301: 2-49 ♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦
Sequence: MDKYFCTGC GYIYDPRLGD PDNGVPRGTP FEELPEDWRC PICTAPESKF LPDHYEE HMM: 425-468 ALI: 3-46 YFCTGC GYIYDPRLGD PDNGVPRGTP FEELPEDWRC PICTAPES ENV: 1-55 DKYFCTGC GYIYDPRLGD PDNGVPRGTP FEELPEDWRC PICTAPESKF LPDHYEE Position: 10 20 30 40 50
Sequence: MEGMRNSES RYDVVIIGGG PAGLTAGLYA SRGGLKSLLL EGESSVSQIT VTDLVENYPG FPEGINGYDL VERFKTQTRQ FGLTIVTDDV RVVCREQQAP GGEESWIVQG NRGAYSTLAV ILATGANWRH LGVPGEEAFA GKGVSYCATC DGPFYRDREV VVVGGGDTAV QEALFLTRFA RKVTIVHRRD RLRATPVLQK KALSHERIEF AWNSVVEEIQ GETFVEGVKI RNLKNPDLSR VIPADGAFVF VGLTPNTEFI RNVVDCDENG YILADSAMRT SAPGIFACGD CIAKLLRQVV TACGDAATAA FSAQLHVEDL KGDSYSGRGI
10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
PF07992: 10-303 ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌◌◌◌◌◌◌ ◌◌◌◌
Sequence: MEGMRNSES RYDVVIIGGG PAGLTAGLYA SRGGLKSLLL EGESSVSQIT VTDLVENYPG FPEGINGYDL VERFKTQTRQ FGLTIVTDDV RVVCREQQAP GGEESWIVQG NRGAYSTLAV ILATGANWRH LGVPGEEAFA GKGVSYCATC DGPFYRDREV VVVGGGDTAV QEALFLTRFA RKVTIVHRRD RLRATPVLQK KALSHERIEF AWNSVVEEIQ GETFVEGVKI RNLKNPDLSR VIPADGAFVF VGLTPNTEFI RNVVDCDENG YILADSAMRT SAPGIFACGD CIAKLLRQVV TACGDAATAA FSAQLHVEDL KGDSYSGRGI HMM: 3-27 MRNSES RYDVVIIGGG PAGLTAGLY ALI: 8-32 S RYDVVIIGGG PAGLTAGLYA SRGG ENV: 6-81 SES RYDVVIIGGG PAGLTAGLYA SRGGLKSLLL EGESSVSQIT VTDLVENYPG FPEGINGYDL VERFKTQTRQ FGL Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
Sequence: MEGMRNSES RYDVVIIGGG PAGLTAGLYA SRGGLKSLLL EGESSVSQIT VTDLVENYPG FPEGINGYDL VERFKTQTRQ FGLTIVTDDV RVVCREQQAP GGEESWIVQG NRGAYSTLAV ILATGANWRH LGVPGEEAFA GKGVSYCATC DGPFYRDREV VVVGGGDTAV QEALFLTRFA RKVTIVHRRD RLRATPVLQK KALSHERIEF AWNSVVEEIQ GETFVEGVKI RNLKNPDLSR VIPADGAFVF VGLTPNTEFI RNVVDCDENG YILADSAMRT SAPGIFACGD CIAKLLRQVV TACGDAATAA FSAQLHVEDL KGDSYSGRGI HMM: 154-216 RDREV VVVGGGDTAV QEALFLTRFA RKVTIVHRRD RLRATPVLQK KALSHERIEF AWNSVVEE ALI: 132-194 PGEEAFA GKGVSYCATC DGPFYRDREV VVVGGGDTAV QEALFLTRFA RKVTIVHRRD RLRATP ENV: 113-217 YSTLAV ILATGANWRH LGVPGEEAFA GKGVSYCATC DGPFYRDREV VVVGGGDTAV QEALFLTRFA RKVTIVHRRD RLRATPVLQK KALSHERIEF AWNSVVEEI Position: 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320
Sequence: MEKEKNNYG DVMVVGGGIS GIQASLDLAT AGFKVFLVET SPSIGGHMAQ LDKTFPTNDC SM
10 20 30 40 50 60
PF12831: 9-48 ♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦♦ ♦♦♦♦♦♦♦♦♦
Sequence: MEKEKNNYG DVMVVGGGIS GIQASLDLAT AGFKVFLVET SPSIGGHMAQ LDKTFPTNDC SM HMM: 2-45 KEKNNYG DVMVVGGGIS GIQASLDLAT AGFKVFLVET SPSIGGH ALI: 5-46 NNYG DVMVVGGGIS GIQASLDLAT AGFKVFLVET SPSIGGHM ENV: 4-55 KNNYG DVMVVGGGIS GIQASLDLAT AGFKVFLVET SPSIGGHMAQ LDKTFPT Position: 10 20 30 40 50 60
No PFAM domains
Sequence: MEKEKNNYG DVMVVGGGIS GIQASLDLAT AGFKVFLVET SPSIGGHMAQ LDKTFPTNDC SM HMM: 2-45 KEKNNYG DVMVVGGGIS GIQASLDLAT AGFKVFLVET SPSIGGH ALI: 5-46 NNYG DVMVVGGGIS GIQASLDLAT AGFKVFLVET SPSIGGHM ENV: 4-55 KNNYG DVMVVGGGIS GIQASLDLAT AGFKVFLVET SPSIGGHMAQ LDKTFPT Position: 10 20 30 40 50 60