Small Microbes Pathway Profiler

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◀ domain architecture  ·  operons  ·  ❔ guide

Gene activity

Syntrophomonas erecta sporosyntropha Sespor · 1 genes
1
genes
1
KO-annotated
2
reactions
3
pathways

Activity by pathway — click to expand; ranked by genes involved

Purine metabolismMetabolism; Nucleotide metabolism1 genes · 2 rxns
Sesp_00591 K00602 purH R01127
IMP + H2O <=> 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
IMP 1,2-hydrolase (decyclizing)
Sesp_00591 K00602 purH R04560
10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase
One carbon pool by folateMetabolism; Metabolism of cofactors and vitamins1 genes · 2 rxns
Sesp_00591 K00602 purH R01127
IMP + H2O <=> 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
IMP 1,2-hydrolase (decyclizing)
Sesp_00591 K00602 purH R04560
10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase
Antifolate resistanceHuman Diseases; Drug resistance: antineoplastic1 genes · 2 rxns
Sesp_00591 K00602 purH R01127
IMP + H2O <=> 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
IMP 1,2-hydrolase (decyclizing)
Sesp_00591 K00602 purH R04560
10-Formyltetrahydrofolate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide <=> Tetrahydrofolate + 1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 1 genes
Sesp_00591
Biosynthesis of secondary metabolites 1 genes
Sesp_00591
Map 01130 1 genes
Sesp_00591

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Sesp_00591 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH 2.1.2.3,3.5.4.10 R01127,R04560
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