Small Microbes Pathway Profiler

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Gene activity

Syntrophomonas erecta sporosyntropha Sespor · 1 genes
1
genes
1
KO-annotated
2
reactions
6
pathways

Activity by pathway — click to expand; ranked by genes involved

Glycine, serine and threonine metabolismMetabolism; Amino acid metabolism1 genes · 2 rxns
Sesp_00955 K00600 glyA, SHMT R00945
5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase
Sesp_00955 K00600 glyA, SHMT R09099
L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O
5,10-methylenetetrahydromethanopterin:glycine hydroxymethyltransferase
Cyanoamino acid metabolismMetabolism; Metabolism of other amino acids1 genes · 2 rxns
Sesp_00955 K00600 glyA, SHMT R00945
5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase
Sesp_00955 K00600 glyA, SHMT R09099
L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O
5,10-methylenetetrahydromethanopterin:glycine hydroxymethyltransferase
Glyoxylate and dicarboxylate metabolismMetabolism; Carbohydrate metabolism1 genes · 2 rxns
Sesp_00955 K00600 glyA, SHMT R00945
5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase
Sesp_00955 K00600 glyA, SHMT R09099
L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O
5,10-methylenetetrahydromethanopterin:glycine hydroxymethyltransferase
One carbon pool by folateMetabolism; Metabolism of cofactors and vitamins1 genes · 2 rxns
Sesp_00955 K00600 glyA, SHMT R00945
5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase
Sesp_00955 K00600 glyA, SHMT R09099
L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O
5,10-methylenetetrahydromethanopterin:glycine hydroxymethyltransferase
Methane metabolismMetabolism; Energy metabolism1 genes · 2 rxns
Sesp_00955 K00600 glyA, SHMT R00945
5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase
Sesp_00955 K00600 glyA, SHMT R09099
L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O
5,10-methylenetetrahydromethanopterin:glycine hydroxymethyltransferase
Antifolate resistanceHuman Diseases; Drug resistance: antineoplastic1 genes · 2 rxns
Sesp_00955 K00600 glyA, SHMT R00945
5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine
5,10-methylenetetrahydrofolate:glycine hydroxymethyltransferase
Sesp_00955 K00600 glyA, SHMT R09099
L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O
5,10-methylenetetrahydromethanopterin:glycine hydroxymethyltransferase

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 1 genes
Sesp_00955
Biosynthesis of secondary metabolites 1 genes
Sesp_00955
Microbial metabolism in diverse environments 1 genes
Sesp_00955
Map 01130 1 genes
Sesp_00955
Carbon metabolism 1 genes
Sesp_00955
Biosynthesis of amino acids 1 genes
Sesp_00955

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Sesp_00955 serine hydroxymethyltransferase K00600 glyA, SHMT 2.1.2.1 R00945,R09099
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