Small Microbes Pathway Profiler

Domain Counts
Profiler Search and BLAST
CAZy ▾
CAZyme Browser CAzy - DBCAN (original) CAZyme protein counts Proteome Coverage Summary
Search ▾
Text search Domain display search
Pathways ▾
Nitrogen Fixation CANT-Hyd
UMAP
◀ domain architecture  ·  operons  ·  ❔ guide

Gene activity

Syntrophomonas wolfei saponavida · 1 genes
1
genes
1
KO-annotated
6
reactions
7
pathways

Activity by pathway — click to expand; ranked by genes involved

Glycolysis / GluconeogenesisMetabolism; Carbohydrate metabolism1 genes · 6 rxns
Sws_00515 K00382 DLD, lpd, pdhD R00209
Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+
pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate dehydrogenase complex
Sws_00515 K00382 DLD, lpd, pdhD R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Sws_00515 K00382 DLD, lpd, pdhD R01698
Dihydrolipoamide + NAD+ <=> Lipoamide + NADH + H+
dihydrolipoamide:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R03815
Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+
dihydrolipoylprotein:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R07618
Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R08549
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
2-oxoglutarate:NAD+ 2-oxidoreductase (CoA-succinylating); 2-oxoglutarate dehydrogenase complex
Citrate cycle (TCA cycle)Metabolism; Carbohydrate metabolism1 genes · 6 rxns
Sws_00515 K00382 DLD, lpd, pdhD R00209
Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+
pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate dehydrogenase complex
Sws_00515 K00382 DLD, lpd, pdhD R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Sws_00515 K00382 DLD, lpd, pdhD R01698
Dihydrolipoamide + NAD+ <=> Lipoamide + NADH + H+
dihydrolipoamide:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R03815
Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+
dihydrolipoylprotein:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R07618
Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R08549
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
2-oxoglutarate:NAD+ 2-oxidoreductase (CoA-succinylating); 2-oxoglutarate dehydrogenase complex
Glycine, serine and threonine metabolismMetabolism; Amino acid metabolism1 genes · 6 rxns
Sws_00515 K00382 DLD, lpd, pdhD R00209
Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+
pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate dehydrogenase complex
Sws_00515 K00382 DLD, lpd, pdhD R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Sws_00515 K00382 DLD, lpd, pdhD R01698
Dihydrolipoamide + NAD+ <=> Lipoamide + NADH + H+
dihydrolipoamide:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R03815
Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+
dihydrolipoylprotein:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R07618
Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R08549
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
2-oxoglutarate:NAD+ 2-oxidoreductase (CoA-succinylating); 2-oxoglutarate dehydrogenase complex
Valine, leucine and isoleucine degradationMetabolism; Amino acid metabolism1 genes · 6 rxns
Sws_00515 K00382 DLD, lpd, pdhD R00209
Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+
pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate dehydrogenase complex
Sws_00515 K00382 DLD, lpd, pdhD R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Sws_00515 K00382 DLD, lpd, pdhD R01698
Dihydrolipoamide + NAD+ <=> Lipoamide + NADH + H+
dihydrolipoamide:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R03815
Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+
dihydrolipoylprotein:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R07618
Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R08549
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
2-oxoglutarate:NAD+ 2-oxidoreductase (CoA-succinylating); 2-oxoglutarate dehydrogenase complex
Pyruvate metabolismMetabolism; Carbohydrate metabolism1 genes · 6 rxns
Sws_00515 K00382 DLD, lpd, pdhD R00209
Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+
pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate dehydrogenase complex
Sws_00515 K00382 DLD, lpd, pdhD R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Sws_00515 K00382 DLD, lpd, pdhD R01698
Dihydrolipoamide + NAD+ <=> Lipoamide + NADH + H+
dihydrolipoamide:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R03815
Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+
dihydrolipoylprotein:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R07618
Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R08549
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
2-oxoglutarate:NAD+ 2-oxidoreductase (CoA-succinylating); 2-oxoglutarate dehydrogenase complex
Glyoxylate and dicarboxylate metabolismMetabolism; Carbohydrate metabolism1 genes · 6 rxns
Sws_00515 K00382 DLD, lpd, pdhD R00209
Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+
pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate dehydrogenase complex
Sws_00515 K00382 DLD, lpd, pdhD R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Sws_00515 K00382 DLD, lpd, pdhD R01698
Dihydrolipoamide + NAD+ <=> Lipoamide + NADH + H+
dihydrolipoamide:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R03815
Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+
dihydrolipoylprotein:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R07618
Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R08549
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
2-oxoglutarate:NAD+ 2-oxidoreductase (CoA-succinylating); 2-oxoglutarate dehydrogenase complex
Propanoate metabolismMetabolism; Carbohydrate metabolism1 genes · 6 rxns
Sws_00515 K00382 DLD, lpd, pdhD R00209
Pyruvate + CoA + NAD+ <=> Acetyl-CoA + CO2 + NADH + H+
pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating); pyruvate dehydrogenase complex
Sws_00515 K00382 DLD, lpd, pdhD R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Sws_00515 K00382 DLD, lpd, pdhD R01698
Dihydrolipoamide + NAD+ <=> Lipoamide + NADH + H+
dihydrolipoamide:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R03815
Dihydrolipoylprotein + NAD+ <=> Lipoylprotein + NADH + H+
dihydrolipoylprotein:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R07618
Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+
enzyme N6-(dihydrolipoyl)lysine:NAD+ oxidoreductase
Sws_00515 K00382 DLD, lpd, pdhD R08549
2-Oxoglutarate + CoA + NAD+ <=> Succinyl-CoA + CO2 + NADH + H+
2-oxoglutarate:NAD+ 2-oxidoreductase (CoA-succinylating); 2-oxoglutarate dehydrogenase complex

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 1 genes
Sws_00515
Biosynthesis of secondary metabolites 1 genes
Sws_00515
Microbial metabolism in diverse environments 1 genes
Sws_00515
Map 01130 1 genes
Sws_00515
Carbon metabolism 1 genes
Sws_00515

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Sws_00515 dihydrolipoyl dehydrogenase K00382 DLD, lpd, pdhD 1.8.1.4 R00209,R01221,R01698,R03815,R07618,R08549
↑ Top




v1.00 @copyright 2026 UCLA