Small Microbes Pathway Profiler

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Gene activity

Syntrophomonas wolfei saponavida · 1 genes
1
genes
1
KO-annotated
7
reactions
2
pathways

Activity by pathway — click to expand; ranked by genes involved

Purine metabolismMetabolism; Nucleotide metabolism1 genes · 7 rxns
Sws_01801 K00760 hprT, hpt, HPRT1 R00190
AMP + Diphosphate <=> Adenine + 5-Phospho-alpha-D-ribose 1-diphosphate
AMP:diphosphate phospho-D-ribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R01132
IMP + Diphosphate <=> Hypoxanthine + 5-Phospho-alpha-D-ribose 1-diphosphate
IMP:diphosphate phospho-D-ribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R01229
GMP + Diphosphate <=> Guanine + 5-Phospho-alpha-D-ribose 1-diphosphate
GMP:diphosphate 5-phospho-alpha-D-ribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R02142
Xanthosine 5'-phosphate + Diphosphate <=> Xanthine + 5-Phospho-alpha-D-ribose 1-diphosphate
XMP:pyrophosphate phosphoribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R08237
6-Mercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioinosine-5'-monophosphate + Diphosphate
6-thioinosine 5'-monophosphate:diphosphate phospho-D-ribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R08238
6-Methylmercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Methylthiopurine 5'-monophosphate ribonucleotide + Diphosphate
6-methylthiopurine 5'-monophosphate ribonucleotide:diphosphate phospho-D-ribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R08245
Thioguanine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioguanosine monophosphate + Diphosphate
6-thioguanosine monophosphate:diphosphate phospho-D-ribosyltransferase
Drug metabolism - other enzymesMetabolism; Xenobiotics biodegradation and metabolism1 genes · 7 rxns
Sws_01801 K00760 hprT, hpt, HPRT1 R00190
AMP + Diphosphate <=> Adenine + 5-Phospho-alpha-D-ribose 1-diphosphate
AMP:diphosphate phospho-D-ribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R01132
IMP + Diphosphate <=> Hypoxanthine + 5-Phospho-alpha-D-ribose 1-diphosphate
IMP:diphosphate phospho-D-ribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R01229
GMP + Diphosphate <=> Guanine + 5-Phospho-alpha-D-ribose 1-diphosphate
GMP:diphosphate 5-phospho-alpha-D-ribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R02142
Xanthosine 5'-phosphate + Diphosphate <=> Xanthine + 5-Phospho-alpha-D-ribose 1-diphosphate
XMP:pyrophosphate phosphoribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R08237
6-Mercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioinosine-5'-monophosphate + Diphosphate
6-thioinosine 5'-monophosphate:diphosphate phospho-D-ribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R08238
6-Methylmercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Methylthiopurine 5'-monophosphate ribonucleotide + Diphosphate
6-methylthiopurine 5'-monophosphate ribonucleotide:diphosphate phospho-D-ribosyltransferase
Sws_01801 K00760 hprT, hpt, HPRT1 R08245
Thioguanine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioguanosine monophosphate + Diphosphate
6-thioguanosine monophosphate:diphosphate phospho-D-ribosyltransferase

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 1 genes
Sws_01801
Biosynthesis of secondary metabolites 1 genes
Sws_01801

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Sws_01801 hypoxanthine phosphoribosyltransferase K00760 hprT, hpt, HPRT1; K15780 tilS-hprT 2.4.2.8,6.3.4.19 R00190,R01132,R01229,R02142,R08237,R08238,R08245
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