Small Microbes Pathway Profiler

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Gene activity

Syntrophomonas wolfei subsp. wolfei Goettingen · 1 genes
1
genes
1
KO-annotated
2
reactions
3
pathways

Activity by pathway — click to expand; ranked by genes involved

One carbon pool by folateMetabolism; Metabolism of cofactors and vitamins1 genes · 2 rxns
Swg_00933 K00297 metF, MTHFR R01224
5-Methyltetrahydrofolate + NADP+ <=> 5,10-Methylenetetrahydrofolate + NADPH + H+
5-methyltetrahydrofolate:NADP+ oxidoreductase
Swg_00933 K00297 metF, MTHFR R07168
5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
5-methyltetrahydrofolate:NAD+ oxidoreductase
Other carbon fixation pathwaysMetabolism; Energy metabolism1 genes · 2 rxns
Swg_00933 K00297 metF, MTHFR R01224
5-Methyltetrahydrofolate + NADP+ <=> 5,10-Methylenetetrahydrofolate + NADPH + H+
5-methyltetrahydrofolate:NADP+ oxidoreductase
Swg_00933 K00297 metF, MTHFR R07168
5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
5-methyltetrahydrofolate:NAD+ oxidoreductase
Antifolate resistanceHuman Diseases; Drug resistance: antineoplastic1 genes · 2 rxns
Swg_00933 K00297 metF, MTHFR R01224
5-Methyltetrahydrofolate + NADP+ <=> 5,10-Methylenetetrahydrofolate + NADPH + H+
5-methyltetrahydrofolate:NADP+ oxidoreductase
Swg_00933 K00297 metF, MTHFR R07168
5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
5-methyltetrahydrofolate:NAD+ oxidoreductase

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 1 genes
Swg_00933
Microbial metabolism in diverse environments 1 genes
Swg_00933
Carbon metabolism 1 genes
Swg_00933

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Swg_00933 methylenetetrahydrofolate reductase [NAD(P)H] K00297 metF, MTHFR 1.5.1.20 R01224,R07168
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