Reaction Activity

Gene activity

Syntrophomonas wolfei methylbutyratica 4J5 · 1 genes

genes

KO-annotated

reactions

pathways

Folate biosynthesisMetabolism; Metabolism of cofactors and vitamins1 genes · 3 rxns

Swm_01869 K11754 folC R00942

ATP + Tetrahydrofolate + L-Glutamate <=> ADP + Orthophosphate + THF-L-glutamate

tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming)

Swm_01869 K11754 folC R02237

ATP + Dihydropteroate + L-Glutamate <=> ADP + Orthophosphate + Dihydrofolate

7,8-dihydropteroate:L-glutamate ligase (ADP-forming)

Swm_01869 K11754 folC R04241

ATP + THF-polyglutamate(n) + L-Glutamate <=> ADP + Orthophosphate + THF-polyglutamate(n+1)

tetrahydropteroyl-gamma-polyglutamate:L-glutamate gamma-ligase (ADP-forming)

Metabolic pathways 1 genes

Swm_01869

show cofactors (H₂O, ATP, NAD⁺…) drag nodes · click an edge for the reaction

Locus	Product	KO	EC	Reactions
Swm_01869	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	K11754 folC	6.3.2.12,6.3.2.17	R00942,R02237,R04241