Reaction Activity

Small Microbes Pathway Profiler

Profiler Search and BLAST

◀ domain architecture · operons · ❔ guide

Gene activity

Syntrophomonas erecta DSM 16215 · 1 genes

1

genes

1

KO-annotated

3

reactions

2

pathways

Activity by pathway — click to expand; ranked by genes involved

Thiamine metabolismMetabolism; Metabolism of cofactors and vitamins1 genes · 3 rxns

Ser_00654 K04487 iscS, NFS1 R07460

[Enzyme]-cysteine + L-Cysteine <=> [Enzyme]-S-sulfanylcysteine + L-Alanine

L-cysteine:[enzyme]-cysteine sulfurtransferase

Ser_00654 K04487 iscS, NFS1 R11528

L-Cysteine + [Protein]-L-cysteine <=> L-Alanine + [Protein]-S-sulfanyl-L-cysteine

L-cysteine:sulfur-acceptor sulfurtransferase

Ser_00654 K04487 iscS, NFS1 R11529

[Enzyme]-S-sulfanylcysteine + [Protein]-L-cysteine <=> [Enzyme]-cysteine + [Protein]-S-sulfanyl-L-cysteine

[enzyme]-S-sulfanylcysteine:sulfur-acceptor sulfurtransferase

Sulfur relay systemGenetic Information Processing; Folding, sorting and degradation1 genes · 3 rxns

Ser_00654 K04487 iscS, NFS1 R07460

[Enzyme]-cysteine + L-Cysteine <=> [Enzyme]-S-sulfanylcysteine + L-Alanine

L-cysteine:[enzyme]-cysteine sulfurtransferase

Ser_00654 K04487 iscS, NFS1 R11528

L-Cysteine + [Protein]-L-cysteine <=> L-Alanine + [Protein]-S-sulfanyl-L-cysteine

L-cysteine:sulfur-acceptor sulfurtransferase

Ser_00654 K04487 iscS, NFS1 R11529

[Enzyme]-S-sulfanylcysteine + [Protein]-L-cysteine <=> [Enzyme]-cysteine + [Protein]-S-sulfanyl-L-cysteine

[enzyme]-S-sulfanylcysteine:sulfur-acceptor sulfurtransferase

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 1 genes

Ser_00654

Reaction network — compounds linked by the reactions these genes catalyse

show cofactors (H₂O, ATP, NAD⁺…) drag nodes · click an edge for the reaction

Genes

Locus	Product	KO	EC	Reactions
Ser_00654	cysteine desulfurase NifS	K04487 iscS, NFS1	2.8.1.7	R07460,R11528,R11529

↑ Top

v1.00 @copyright 2026 UCLA