Small Microbes Pathway Profiler

Domain Counts
Profiler Search and BLAST
CAZy ▾
CAZyme Browser CAzy - DBCAN (original) CAZyme protein counts Proteome Coverage Summary
Search ▾
Text search Domain display search
Pathways ▾
Nitrogen Fixation CANT-Hyd
UMAP
◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_CM129641.1:498,878–504,983

Syntrophomonas curvata DSM15682 · 5 genes
5
genes
3
KO-annotated
8
reactions
6
pathways

Activity by pathway — click to expand; ranked by genes involved

Butanoate metabolismMetabolism; Carbohydrate metabolism2 genes · 7 rxns
Scur_00442 K00483 hpaB R02698
4-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Scur_00442 K00483 hpaB R03031
Vinylacetyl-CoA <=> Crotonoyl-CoA
vinylacetyl-CoA Delta3-Delta2-isomerase
Scur_00442 K00483 hpaB R03299
3-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
3-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Scur_00442 K00483 hpaB R10782
4-Hydroxybutyryl-CoA <=> Crotonoyl-CoA + H2O
4-hydroxybutanoyl-CoA hydro-lyase
Scur_00446 K00074 paaH, hbd, fadB, mmgB R01976
(S)-3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Scur_00446 K00074 paaH, hbd, fadB, mmgB R05576
3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Scur_00446 K00074 paaH, hbd, fadB, mmgB R06941
(3S)-3-Hydroxyadipyl-CoA + NAD+ <=> 3-Oxoadipyl-CoA + NADH + H+
(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase
Tyrosine metabolismMetabolism; Amino acid metabolism1 genes · 4 rxns
Scur_00442 K00483 hpaB R02698
4-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Scur_00442 K00483 hpaB R03031
Vinylacetyl-CoA <=> Crotonoyl-CoA
vinylacetyl-CoA Delta3-Delta2-isomerase
Scur_00442 K00483 hpaB R03299
3-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
3-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Scur_00442 K00483 hpaB R10782
4-Hydroxybutyryl-CoA <=> Crotonoyl-CoA + H2O
4-hydroxybutanoyl-CoA hydro-lyase
Other carbon fixation pathwaysMetabolism; Energy metabolism1 genes · 4 rxns
Scur_00442 K00483 hpaB R02698
4-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Scur_00442 K00483 hpaB R03031
Vinylacetyl-CoA <=> Crotonoyl-CoA
vinylacetyl-CoA Delta3-Delta2-isomerase
Scur_00442 K00483 hpaB R03299
3-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
3-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Scur_00442 K00483 hpaB R10782
4-Hydroxybutyryl-CoA <=> Crotonoyl-CoA + H2O
4-hydroxybutanoyl-CoA hydro-lyase
Pantothenate and CoA biosynthesisMetabolism; Metabolism of cofactors and vitamins1 genes · 1 rxns
Scur_00445 K00077 panE, apbA R02472
(R)-Pantoate + NADP+ <=> 2-Dehydropantoate + NADPH + H+
(R)-pantoate:NADP+ 2-oxidoreductase
Phenylalanine metabolismMetabolism; Amino acid metabolism1 genes · 3 rxns
Scur_00446 K00074 paaH, hbd, fadB, mmgB R01976
(S)-3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Scur_00446 K00074 paaH, hbd, fadB, mmgB R05576
3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Scur_00446 K00074 paaH, hbd, fadB, mmgB R06941
(3S)-3-Hydroxyadipyl-CoA + NAD+ <=> 3-Oxoadipyl-CoA + NADH + H+
(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase
Benzoate degradationMetabolism; Xenobiotics biodegradation and metabolism1 genes · 3 rxns
Scur_00446 K00074 paaH, hbd, fadB, mmgB R01976
(S)-3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Scur_00446 K00074 paaH, hbd, fadB, mmgB R05576
3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Scur_00446 K00074 paaH, hbd, fadB, mmgB R06941
(3S)-3-Hydroxyadipyl-CoA + NAD+ <=> 3-Oxoadipyl-CoA + NADH + H+
(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 3 genes
Scur_00442 Scur_00445 Scur_00446
Microbial metabolism in diverse environments 2 genes
Scur_00442 Scur_00446
Carbon metabolism 1 genes
Scur_00442
Degradation of aromatic compounds 1 genes
Scur_00442
Biosynthesis of secondary metabolites 1 genes
Scur_00445

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Scur_00442 4-hydroxyphenylacetate 3-hydroxylase family protein K00483 hpaB; K14534 abfD 1.14.14.9,4.2.1.120,5.3.3.3 R02698,R03031,R03299,R10782
Scur_00443 N-acyl homoserine lactonase family protein — — —
Scur_00444 class I adenylate-forming enzyme family protein — — —
Scur_00445 ketopantoate reductase family protein K00077 panE, apbA 1.1.1.169 R02472
Scur_00446 3-hydroxyacyl-CoA dehydrogenase family protein K00074 paaH, hbd, fadB, mmgB 1.1.1.157 R01976,R05576,R06941
↑ Top




v1.00 @copyright 2026 UCLA