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◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_AP042459.1:2,525,597–2,530,655

Syntrophomonas erecta sporosyntropha Sespor · 4 genes
4
genes
3
KO-annotated
9
reactions
14
pathways

Activity by pathway — click to expand; ranked by genes involved

Tyrosine metabolismMetabolism; Amino acid metabolism1 genes · 4 rxns
Sesp_02381 K00483 hpaB R02698
4-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Sesp_02381 K00483 hpaB R03031
Vinylacetyl-CoA <=> Crotonoyl-CoA
vinylacetyl-CoA Delta3-Delta2-isomerase
Sesp_02381 K00483 hpaB R03299
3-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
3-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Sesp_02381 K00483 hpaB R10782
4-Hydroxybutyryl-CoA <=> Crotonoyl-CoA + H2O
4-hydroxybutanoyl-CoA hydro-lyase
Pantothenate and CoA biosynthesisMetabolism; Metabolism of cofactors and vitamins1 genes · 1 rxns
Sesp_02384 K00077 panE, apbA R02472
(R)-Pantoate + NADP+ <=> 2-Dehydropantoate + NADPH + H+
(R)-pantoate:NADP+ 2-oxidoreductase
Adipocytokine signaling pathwayOrganismal Systems; Endocrine system1 genes · 4 rxns
Sesp_02383 K01897 ACSL, fadD R01280
ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate
palmitate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01406
ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]
long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01558
ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA
oxalate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R04864
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
ThermogenesisOrganismal Systems; Environmental adaptation1 genes · 4 rxns
Sesp_02383 K01897 ACSL, fadD R01280
ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate
palmitate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01406
ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]
long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01558
ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA
oxalate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R04864
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
FerroptosisCellular Processes; Cell growth and death1 genes · 4 rxns
Sesp_02383 K01897 ACSL, fadD R01280
ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate
palmitate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01406
ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]
long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01558
ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA
oxalate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R04864
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
PeroxisomeCellular Processes; Transport and catabolism1 genes · 4 rxns
Sesp_02383 K01897 ACSL, fadD R01280
ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate
palmitate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01406
ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]
long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01558
ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA
oxalate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R04864
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
PPAR signaling pathwayOrganismal Systems; Endocrine system1 genes · 4 rxns
Sesp_02383 K01897 ACSL, fadD R01280
ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate
palmitate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01406
ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]
long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01558
ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA
oxalate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R04864
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
Quorum sensingCellular Processes; Cellular community - prokaryotes1 genes · 4 rxns
Sesp_02383 K01897 ACSL, fadD R01280
ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate
palmitate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01406
ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]
long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01558
ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA
oxalate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R04864
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
Glyoxylate and dicarboxylate metabolismMetabolism; Carbohydrate metabolism1 genes · 4 rxns
Sesp_02383 K01897 ACSL, fadD R01280
ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate
palmitate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01406
ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]
long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01558
ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA
oxalate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R04864
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
Butanoate metabolismMetabolism; Carbohydrate metabolism1 genes · 4 rxns
Sesp_02381 K00483 hpaB R02698
4-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Sesp_02381 K00483 hpaB R03031
Vinylacetyl-CoA <=> Crotonoyl-CoA
vinylacetyl-CoA Delta3-Delta2-isomerase
Sesp_02381 K00483 hpaB R03299
3-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
3-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Sesp_02381 K00483 hpaB R10782
4-Hydroxybutyryl-CoA <=> Crotonoyl-CoA + H2O
4-hydroxybutanoyl-CoA hydro-lyase
Glycerophospholipid metabolismMetabolism; Lipid metabolism1 genes · 4 rxns
Sesp_02383 K01897 ACSL, fadD R01280
ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate
palmitate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01406
ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]
long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01558
ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA
oxalate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R04864
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
Fatty acid degradationMetabolism; Lipid metabolism1 genes · 4 rxns
Sesp_02383 K01897 ACSL, fadD R01280
ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate
palmitate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01406
ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]
long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01558
ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA
oxalate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R04864
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
Fatty acid biosynthesisMetabolism; Lipid metabolism1 genes · 4 rxns
Sesp_02383 K01897 ACSL, fadD R01280
ATP + Hexadecanoic acid + CoA <=> AMP + Palmitoyl-CoA + Diphosphate
palmitate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01406
ATP + Long-chain fatty acid + Acyl-carrier protein <=> AMP + Diphosphate + Long-chain acyl-[acyl-carrier protein]
long-chain-fatty-acid:[acyl-carrier-protein] ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R01558
ATP + Oxalate + CoA <=> AMP + Diphosphate + Oxalyl-CoA
oxalate:CoA ligase (AMP-forming)
Sesp_02383 K01897 ACSL, fadD R04864
Acyl-[acyl-carrier protein] + 2-Acyl-sn-glycero-3-phosphoethanolamine <=> Acyl-carrier protein + Phosphatidylethanolamine
2-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase
Other carbon fixation pathwaysMetabolism; Energy metabolism1 genes · 4 rxns
Sesp_02381 K00483 hpaB R02698
4-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Sesp_02381 K00483 hpaB R03031
Vinylacetyl-CoA <=> Crotonoyl-CoA
vinylacetyl-CoA Delta3-Delta2-isomerase
Sesp_02381 K00483 hpaB R03299
3-Hydroxyphenylacetate + Oxygen + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
3-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating)
Sesp_02381 K00483 hpaB R10782
4-Hydroxybutyryl-CoA <=> Crotonoyl-CoA + H2O
4-hydroxybutanoyl-CoA hydro-lyase

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 3 genes
Sesp_02381 Sesp_02383 Sesp_02384
Fatty acid metabolism 1 genes
Sesp_02383
Degradation of aromatic compounds 1 genes
Sesp_02381
Carbon metabolism 1 genes
Sesp_02381
Microbial metabolism in diverse environments 1 genes
Sesp_02381
Biosynthesis of secondary metabolites 1 genes
Sesp_02384

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Sesp_02381 4-hydroxyphenylacetate 3-hydroxylase family protein K00483 hpaB; K14534 abfD 1.14.14.9,4.2.1.120,5.3.3.3 R02698,R03031,R03299,R10782
Sesp_02382 N-acyl homoserine lactonase family protein — — —
Sesp_02383 class I adenylate-forming enzyme family protein K01897 ACSL, fadD; K02182 caiC; K05939 aas; K22133 AAE3 2.3.1.40,6.2.1.20,6.2.1.3,6.2.1.48,6.2.1.8 R01280,R01406,R01558,R04864
Sesp_02384 ketopantoate reductase family protein K00077 panE, apbA 1.1.1.169 R02472
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