Reaction Activity

Operon NZ_AP042459.1:1,290,465–1,293,466

Syntrophomonas erecta sporosyntropha Sespor · 4 genes

genes

KO-annotated

reactions

pathways

Pantothenate and CoA biosynthesisMetabolism; Metabolism of cofactors and vitamins3 genes · 3 rxns

Sesp_01216 K00606 panB R01226

5,10-Methylenetetrahydrofolate + 3-Methyl-2-oxobutanoic acid + H2O <=> Tetrahydrofolate + 2-Dehydropantoate

5,10-methylenetetrahydrofolate:3-methyl-2-oxobutanoate hydroxymethyltransferase

Sesp_01217 K01918 panC R02473

ATP + (R)-Pantoate + beta-Alanine <=> AMP + Diphosphate + Pantothenate

(R)-pantoate:beta-alanine ligase (AMP-forming)

Sesp_01218 K01579 panD R00489

L-Aspartate <=> beta-Alanine + CO2

L-aspartate 1-carboxy-lyase (beta-alanine-forming)

beta-Alanine metabolismMetabolism; Metabolism of other amino acids2 genes · 2 rxns

Sesp_01217 K01918 panC R02473

ATP + (R)-Pantoate + beta-Alanine <=> AMP + Diphosphate + Pantothenate

(R)-pantoate:beta-alanine ligase (AMP-forming)

Sesp_01218 K01579 panD R00489

L-Aspartate <=> beta-Alanine + CO2

L-aspartate 1-carboxy-lyase (beta-alanine-forming)

Nicotinate and nicotinamide metabolismMetabolism; Metabolism of cofactors and vitamins1 genes · 1 rxns

Sesp_01219 K03517 nadA R04292

Quinolinate + 2 H2O + Orthophosphate <=> Iminoaspartate + Glycerone phosphate

glycerone phosphate:iminosuccinate alkyltransferase (cyclizing)

Metabolic pathways 4 genes

Sesp_01216 Sesp_01217 Sesp_01218 Sesp_01219

Biosynthesis of secondary metabolites 3 genes

Sesp_01216 Sesp_01217 Sesp_01218

show cofactors (H₂O, ATP, NAD⁺…) drag nodes · click an edge for the reaction

Locus	Product	KO	EC	Reactions
Sesp_01216	3-methyl-2-oxobutanoate hydroxymethyltransferase	K00606 panB	2.1.2.11	R01226
Sesp_01217	pantoate--beta-alanine ligase	K01918 panC	6.3.2.1	R02473
Sesp_01218	aspartate 1-decarboxylase	K01579 panD	4.1.1.11	R00489
Sesp_01219	quinolinate synthase NadA	K03517 nadA	2.5.1.72	R04292