Activity by pathway — click to expand; ranked by genes involved
Pyrimidine metabolismMetabolism; Nucleotide metabolism1 genes · 1 rxns
Sesp_02375 K00560 thyA, TYMS R02101dUMP + 5,10-Methylenetetrahydrofolate <=> Dihydrofolate + dTMP
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase One carbon pool by folateMetabolism; Metabolism of cofactors and vitamins1 genes · 1 rxns
Sesp_02375 K00560 thyA, TYMS R02101dUMP + 5,10-Methylenetetrahydrofolate <=> Dihydrofolate + dTMP
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase Antifolate resistanceHuman Diseases; Drug resistance: antineoplastic1 genes · 1 rxns
Sesp_02375 K00560 thyA, TYMS R02101dUMP + 5,10-Methylenetetrahydrofolate <=> Dihydrofolate + dTMP
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase Overview / global maps (every metabolic gene maps here)
Metabolic pathways
1 genes
Reaction network — compounds linked by the reactions these genes catalyse
drag nodes · click an edge for the reaction
Genes
| Locus | Product | KO | EC | Reactions |
|---|
| Sesp_02373 |
DUF2197 domain-containing protein |
— |
— |
— |
| Sesp_02374 |
alpha/beta hydrolase |
K06889 K06889; K07397 yhfA |
— |
— |
| Sesp_02375 |
IMPACT family protein |
K00560 thyA, TYMS |
2.1.1.45 |
R02101 |
