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◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_CM161535.1:347,768–353,559

Syntrophomonas wolfei saponavida · 6 genes
6
genes
4
KO-annotated
5
reactions
3
pathways

Activity by pathway — click to expand; ranked by genes involved

Porphyrin metabolismMetabolism; Metabolism of cofactors and vitamins2 genes · 5 rxns
Sws_00317 K02302 cysG R02864
Siroheme + 2 H+ <=> Fe2+ + Sirohydrochlorin
S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase
Sws_00317 K02302 cysG R03165
Hydroxymethylbilane <=> Uroporphyrinogen III + H2O
hydroxymethylbilane hydro-lyase(cyclizing)
Sws_00317 K02302 cysG R03194
2 S-Adenosyl-L-methionine + Uroporphyrinogen III <=> 2 S-Adenosyl-L-homocysteine + Precorrin 2
S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase
Sws_00317 K02302 cysG R03947
Precorrin 2 + NAD+ <=> Sirohydrochlorin + NADH + H+
S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase
Sws_00318 K01749 hemC, HMBS R00084
4 Porphobilinogen + H2O <=> Hydroxymethylbilane + 4 Ammonia
porphobilinogen:(4-[2-carboxyethyl]-3-[carboxymethyl]pyrrol-2-yl)methyltransferase (hydrolysing); porphobilinogen ammonia-lyase (polymerizing)
Protein exportGenetic Information Processing; Folding, sorting and degradation1 genes · 0 rxns
Sws_00321 K03116 tatA
Bacterial secretion systemEnvironmental Information Processing; Membrane transport1 genes · 0 rxns
Sws_00321 K03116 tatA

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 2 genes
Sws_00317 Sws_00318
Biosynthesis of secondary metabolites 2 genes
Sws_00317 Sws_00318
Microbial metabolism in diverse environments 2 genes
Sws_00317 Sws_00318

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Sws_00316 radical SAM protein K22226 ahbC — —
Sws_00317 uroporphyrinogen-III C-methyltransferase K02302 cysG; K02303 cobA; K13542 cobA-hemD 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 R02864,R03165,R03194,R03947
Sws_00318 hydroxymethylbilane synthase K01749 hemC, HMBS 2.5.1.61 R00084
Sws_00319 glutamyl-tRNA reductase — — —
Sws_00320 precorrin-2 dehydrogenase/sirohydrochlorin ferrochelatase family protein — — —
Sws_00321 twin-arginine translocase TatA/TatE family subunit K03116 tatA — —
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