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◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_CM161535.1:662,776–666,394

Syntrophomonas wolfei saponavida · 4 genes
4
genes
4
KO-annotated
22
reactions
4
pathways

Activity by pathway — click to expand; ranked by genes involved

Fatty acid biosynthesisMetabolism; Lipid metabolism4 genes · 23 rxns
Sws_00620 K00059 fabG, OAR1 R04533
(3R)-3-Hydroxybutanoyl-[acyl-carrier protein] + NADP+ <=> Acetoacetyl-[acp] + NADPH + H+
(3R)-3-hydroxybutanoyl-[acyl-carrier protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04534
(3R)-3-Hydroxydecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxodecanoyl-[acp] + NADPH
(3R)-3-hydroxydecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04536
(3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxooctanoyl-[acp] + NADPH + H+
(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04543
(3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexadecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04566
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxotetradecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04953
(3R)-3-Hydroxyhexanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexanoyl-[acp] + NADPH + H+
(3R)-3-hydroxyhexanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04964
(3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxydodecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R07759
3-Oxostearoyl-CoA + NADPH + H+ <=> 3-Hydroxyoctadecanoyl-CoA + NADP+
3-hydroxyoctadecanoyl-CoA:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R07763
3-Oxostearoyl-[acp] + NADPH + H+ <=> (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein] + NADP+
Sws_00620 K00059 fabG, OAR1 R10116
3-Ketoglutaryl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxyglutaryl-[acp] methyl ester + NADP+
3-hydroxyglutaryl-[acp]-methyl-ester:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R10120
3-Ketopimeloyl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxypimeloyl-[acp] methyl ester + NADP+
3-hydroxypimeloyl-[acp]-methyl-ester:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R11671
Malonyl-CoA + Acetyl-CoA <=> Dodecanoyl-[acyl-carrier protein]
Sws_00621 K00645 fabD, MCAT, MCT1 R01626
Malonyl-CoA + Acyl-carrier protein <=> CoA + Malonyl-[acyl-carrier protein]
malonyl-CoA:[acyl-carrier-protein] S-malonyltransferase
Sws_00621 K00645 fabD, MCAT, MCT1 R11671
Malonyl-CoA + Acetyl-CoA <=> Dodecanoyl-[acyl-carrier protein]
Sws_00622 K02371 fabK R04429
Butyryl-[acp] + NAD+ <=> But-2-enoyl-[acyl-carrier protein] + NADH + H+
butyryl-[acp]:NAD+ trans-2-oxidoreductase
Sws_00622 K02371 fabK R04724
Dodecanoyl-[acyl-carrier protein] + NAD+ <=> trans-Dodec-2-enoyl-[acp] + NADH + H+
dodecanoyl-[acp]:NAD+ trans-2-oxidoreductase
Sws_00622 K02371 fabK R04955
Hexanoyl-[acp] + NAD+ <=> trans-Hex-2-enoyl-[acp] + NADH + H+
hexanoyl-[acp]:NAD+ trans-2-oxidoreductase
Sws_00622 K02371 fabK R04958
Octanoyl-[acp] + NAD+ <=> trans-Oct-2-enoyl-[acp] + NADH + H+
octanoyl-[acp]:NAD+ trans-2-oxidoreductase
Sws_00622 K02371 fabK R04961
Decanoyl-[acp] + NAD+ <=> trans-Dec-2-enoyl-[acp] + NADH + H+
decanoyl-[acp]:NAD+ trans-2-oxidoreductase
Sws_00622 K02371 fabK R04966
Tetradecanoyl-[acp] + NAD+ <=> trans-Tetradec-2-enoyl-[acp] + NADH + H+
tetradecanoyl-[acp]:NAD+ trans-2-oxidoreductase
Sws_00622 K02371 fabK R04969
Hexadecanoyl-[acp] + NAD+ <=> trans-Hexadec-2-enoyl-[acp] + NADH + H+
hexadecanoyl-[acp]:NAD+ trans-2-oxidoreductase
Sws_00622 K02371 fabK R07765
(2E)-Octadecenoyl-[acp] + NADH + H+ <=> Octadecanoyl-[acyl-carrier protein] + NAD+
octadecanoyl-[acp]:NAD+ trans-2-oxidoreductase
Sws_00623 K00648 fabH R10707
Acetyl-CoA + Malonyl-[acyl-carrier protein] <=> Acetoacetyl-[acp] + CoA + CO2
acetyl-CoA:malonyl-[acyl-carrier protein] C-acetyltransferase (decarboxylating)
Prodigiosin biosynthesisMetabolism; Biosynthesis of other secondary metabolites2 genes · 14 rxns
Sws_00620 K00059 fabG, OAR1 R04533
(3R)-3-Hydroxybutanoyl-[acyl-carrier protein] + NADP+ <=> Acetoacetyl-[acp] + NADPH + H+
(3R)-3-hydroxybutanoyl-[acyl-carrier protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04534
(3R)-3-Hydroxydecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxodecanoyl-[acp] + NADPH
(3R)-3-hydroxydecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04536
(3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxooctanoyl-[acp] + NADPH + H+
(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04543
(3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexadecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04566
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxotetradecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04953
(3R)-3-Hydroxyhexanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexanoyl-[acp] + NADPH + H+
(3R)-3-hydroxyhexanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04964
(3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxydodecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R07759
3-Oxostearoyl-CoA + NADPH + H+ <=> 3-Hydroxyoctadecanoyl-CoA + NADP+
3-hydroxyoctadecanoyl-CoA:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R07763
3-Oxostearoyl-[acp] + NADPH + H+ <=> (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein] + NADP+
Sws_00620 K00059 fabG, OAR1 R10116
3-Ketoglutaryl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxyglutaryl-[acp] methyl ester + NADP+
3-hydroxyglutaryl-[acp]-methyl-ester:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R10120
3-Ketopimeloyl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxypimeloyl-[acp] methyl ester + NADP+
3-hydroxypimeloyl-[acp]-methyl-ester:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R11671
Malonyl-CoA + Acetyl-CoA <=> Dodecanoyl-[acyl-carrier protein]
Sws_00621 K00645 fabD, MCAT, MCT1 R01626
Malonyl-CoA + Acyl-carrier protein <=> CoA + Malonyl-[acyl-carrier protein]
malonyl-CoA:[acyl-carrier-protein] S-malonyltransferase
Sws_00621 K00645 fabD, MCAT, MCT1 R11671
Malonyl-CoA + Acetyl-CoA <=> Dodecanoyl-[acyl-carrier protein]
Biotin metabolismMetabolism; Metabolism of cofactors and vitamins1 genes · 12 rxns
Sws_00620 K00059 fabG, OAR1 R04533
(3R)-3-Hydroxybutanoyl-[acyl-carrier protein] + NADP+ <=> Acetoacetyl-[acp] + NADPH + H+
(3R)-3-hydroxybutanoyl-[acyl-carrier protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04534
(3R)-3-Hydroxydecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxodecanoyl-[acp] + NADPH
(3R)-3-hydroxydecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04536
(3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxooctanoyl-[acp] + NADPH + H+
(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04543
(3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexadecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04566
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxotetradecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04953
(3R)-3-Hydroxyhexanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexanoyl-[acp] + NADPH + H+
(3R)-3-hydroxyhexanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04964
(3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxydodecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R07759
3-Oxostearoyl-CoA + NADPH + H+ <=> 3-Hydroxyoctadecanoyl-CoA + NADP+
3-hydroxyoctadecanoyl-CoA:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R07763
3-Oxostearoyl-[acp] + NADPH + H+ <=> (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein] + NADP+
Sws_00620 K00059 fabG, OAR1 R10116
3-Ketoglutaryl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxyglutaryl-[acp] methyl ester + NADP+
3-hydroxyglutaryl-[acp]-methyl-ester:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R10120
3-Ketopimeloyl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxypimeloyl-[acp] methyl ester + NADP+
3-hydroxypimeloyl-[acp]-methyl-ester:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R11671
Malonyl-CoA + Acetyl-CoA <=> Dodecanoyl-[acyl-carrier protein]
Biosynthesis of unsaturated fatty acidsMetabolism; Lipid metabolism1 genes · 12 rxns
Sws_00620 K00059 fabG, OAR1 R04533
(3R)-3-Hydroxybutanoyl-[acyl-carrier protein] + NADP+ <=> Acetoacetyl-[acp] + NADPH + H+
(3R)-3-hydroxybutanoyl-[acyl-carrier protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04534
(3R)-3-Hydroxydecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxodecanoyl-[acp] + NADPH
(3R)-3-hydroxydecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04536
(3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxooctanoyl-[acp] + NADPH + H+
(3R)-3-hydroxyoctanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04543
(3R)-3-Hydroxypalmitoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexadecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxypalmitoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04566
(3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxotetradecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04953
(3R)-3-Hydroxyhexanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxohexanoyl-[acp] + NADPH + H+
(3R)-3-hydroxyhexanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R04964
(3R)-3-Hydroxydodecanoyl-[acyl-carrier protein] + NADP+ <=> 3-Oxododecanoyl-[acp] + NADPH + H+
(3R)-3-hydroxydodecanoyl-[acyl-carrier-protein]:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R07759
3-Oxostearoyl-CoA + NADPH + H+ <=> 3-Hydroxyoctadecanoyl-CoA + NADP+
3-hydroxyoctadecanoyl-CoA:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R07763
3-Oxostearoyl-[acp] + NADPH + H+ <=> (3R)-3-Hydroxyoctadecanoyl-[acyl-carrier protein] + NADP+
Sws_00620 K00059 fabG, OAR1 R10116
3-Ketoglutaryl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxyglutaryl-[acp] methyl ester + NADP+
3-hydroxyglutaryl-[acp]-methyl-ester:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R10120
3-Ketopimeloyl-[acp] methyl ester + NADPH + H+ <=> 3-Hydroxypimeloyl-[acp] methyl ester + NADP+
3-hydroxypimeloyl-[acp]-methyl-ester:NADP+ oxidoreductase
Sws_00620 K00059 fabG, OAR1 R11671
Malonyl-CoA + Acetyl-CoA <=> Dodecanoyl-[acyl-carrier protein]

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 4 genes
Sws_00620 Sws_00621 Sws_00622 Sws_00623
Fatty acid metabolism 4 genes
Sws_00620 Sws_00621 Sws_00622 Sws_00623
Map 01130 2 genes
Sws_00620 Sws_00621

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Sws_00620 3-oxoacyl-[acyl-carrier-protein] reductase K00059 fabG, OAR1 1.1.1.100 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671
Sws_00621 ACP S-malonyltransferase K00645 fabD, MCAT, MCT1 2.3.1.39 R01626,R11671
Sws_00622 nitronate monooxygenase K02371 fabK 1.3.1.9 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765
Sws_00623 beta-ketoacyl-ACP synthase III K00648 fabH 2.3.1.180 R10707
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