Reaction Activity

Operon NZ_CM161535.1:1,317,899–1,320,538

Syntrophomonas wolfei saponavida · 4 genes

genes

KO-annotated

reactions

pathways

Folate biosynthesisMetabolism; Metabolism of cofactors and vitamins2 genes · 4 rxns

Sws_01241 K00796 folP R03066

6-(Hydroxymethyl)-7,8-dihydropterin + 4-Aminobenzoate <=> Dihydropteroate + H2O

6-(hydroxymethyl)-7,8-dihydropterin:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase

Sws_01241 K00796 folP R03067

6-Hydroxymethyl-7,8-dihydropterin diphosphate + 4-Aminobenzoate <=> Diphosphate + Dihydropteroate

(7,8-dihydropterin-6-yl)methyl diphosphate:4-aminobenzoate 2-amino-4-hydroxy-7,8-dihydropteridine-6-methenyltransferase

Sws_01243 K00950 folK R03503

ATP + 6-(Hydroxymethyl)-7,8-dihydropterin <=> AMP + 6-Hydroxymethyl-7,8-dihydropterin diphosphate

ATP:6-hydroxymethyl-7,8-dihydropterin 6'-diphosphotransferase

Sws_01243 K00950 folK R03504

7,8-Dihydroneopterin <=> Glycolaldehyde + 6-(Hydroxymethyl)-7,8-dihydropterin

7,8-dihydroneopterin glycolaldehyde-lyase [6-(hydroxymethyl)-7,8-dihydropterin-forming]

Metabolic pathways 2 genes

Sws_01241 Sws_01243

show cofactors (H₂O, ATP, NAD⁺…) drag nodes · click an edge for the reaction

Locus	Product	KO	EC	Reactions
Sws_01240	HD domain-containing protein	K06950 K06950	—	—
Sws_01241	dihydropteroate synthase	K00796 folP	2.5.1.15	R03066,R03067
Sws_01242	dihydroneopterin aldolase	—	—	—
Sws_01243	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	K00950 folK; K13940 sulD	2.7.6.3,4.1.2.25	R03503,R03504