Small Microbes Pathway Profiler

Domain Counts
Profiler Search and BLAST
CAZy ▾
CAZyme Browser CAzy - DBCAN (original) CAZyme protein counts Proteome Coverage Summary
Search ▾
Text search Domain display search
Pathways ▾
Nitrogen Fixation CANT-Hyd
UMAP
◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_CM161535.1:1,453,251–1,457,833

Syntrophomonas wolfei saponavida · 4 genes
4
genes
4
KO-annotated
4
reactions
2
pathways

Activity by pathway — click to expand; ranked by genes involved

Thiamine metabolismMetabolism; Metabolism of cofactors and vitamins2 genes · 2 rxns
Sws_01354 K03147 thiC R03472
Aminoimidazole ribotide + S-Adenosyl-L-methionine <=> 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO
5-amino-1-(5-phospho-D-ribosyl)imidazole formate-lyase (decarboxylating, 4-amino-2-methyl-5-phosphomethylpyrimidine-forming)
Sws_01355 K03147 thiC R03472
Aminoimidazole ribotide + S-Adenosyl-L-methionine <=> 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO
5-amino-1-(5-phospho-D-ribosyl)imidazole formate-lyase (decarboxylating, 4-amino-2-methyl-5-phosphomethylpyrimidine-forming)
Porphyrin metabolismMetabolism; Metabolism of cofactors and vitamins2 genes · 3 rxns
Sws_01356 K02233 E2.7.8.26, cobS, cobV R05223
Cobamide coenzyme + GMP <=> Adenosine-GDP-cobinamide + alpha-Ribazole
Sws_01356 K02233 E2.7.8.26, cobS, cobV R11174
Adenosine-GDP-cobinamide + N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole <=> GMP + Adenosylcobalamin 5'-phosphate
adenosylcobinamide-GDP:alpha-ribazole adenosylcobinamide-phosphotransferase
Sws_01357 K00768 E2.4.2.21, cobU, cobT R04148
Nicotinate D-ribonucleotide + Dimethylbenzimidazole <=> Nicotinate + N1-(5-Phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole + H+
nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 4 genes
Sws_01354 Sws_01355 Sws_01356 Sws_01357

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Sws_01354 phosphomethylpyrimidine synthase ThiC K03147 thiC; K22465 bzaA_B 4.1.99.17,4.1.99.23 R03472
Sws_01355 B12 lower ligand biosynthesis ThiC-like protein BzaB K03147 thiC; K22465 bzaA_B 4.1.99.17,4.1.99.23 R03472
Sws_01356 adenosylcobinamide-GDP ribazoletransferase K02233 E2.7.8.26, cobS, cobV 2.7.8.26 R05223,R11174
Sws_01357 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase K00768 E2.4.2.21, cobU, cobT 2.4.2.21 R04148
↑ Top




v1.00 @copyright 2026 UCLA