Small Microbes Pathway Profiler

Domain Counts
Profiler Search and BLAST
CAZy ▾
CAZyme Browser CAzy - DBCAN (original) CAZyme protein counts Proteome Coverage Summary
Search ▾
Text search Domain display search
Pathways ▾
Nitrogen Fixation CANT-Hyd
UMAP
◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_CM161535.1:3,241,428–3,245,329

Syntrophomonas wolfei saponavida · 4 genes
4
genes
3
KO-annotated
17
reactions
3
pathways

Activity by pathway — click to expand; ranked by genes involved

Cysteine and methionine metabolismMetabolism; Amino acid metabolism3 genes · 29 rxns
Sws_02997 K01738 cysK R00897
O-Acetyl-L-serine + Hydrogen sulfide <=> L-Cysteine + Acetate
O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase; O3-acetyl-L-serine acetate-lyase (adding hydrogen sulfide)
Sws_02997 K01738 cysK R03601
O-Acetyl-L-serine + Hydrogen selenide <=> L-Selenocysteine + Acetate
O3-acetyl-L-serine acetate-lyase (adding hydrogen sulfide)
Sws_02997 K01738 cysK R04859
O-Acetyl-L-serine + Thiosulfate + Thioredoxin + H+ <=> L-Cysteine + Sulfite + Thioredoxin disulfide + Acetate
O3-acetyl-L-serine:thiosulfate 2-amino-2-carboxyethyltransferase (reducing, L-cysteine-forming); O3-acetyl-L-serine acetate-lyase (thiosulfate-reducing, L-cysteine-forming)
Sws_02998 K01739 metB R00654
L-Methionine + H2O <=> Methanethiol + Ammonia + 2-Oxobutanoate
L-methionine methanethiol-lyase (deaminating;2-oxobutanoate-forming)
Sws_02998 K01739 metB R00782
L-Cysteine + H2O <=> Hydrogen sulfide + Pyruvate + Ammonia
L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming)
Sws_02998 K01739 metB R00999
O-Succinyl-L-homoserine + H2O <=> 2-Oxobutanoate + Succinate + Ammonia
O-succinyl-L-homoserine succinate-lyase (deaminating; 2-oxobutanoate-forming)
Sws_02998 K01739 metB R01286
L-Cystathionine + H2O <=> L-Homocysteine + Ammonia + Pyruvate
L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)
Sws_02998 K01739 metB R01288
O-Succinyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Succinate
O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide)
Sws_02998 K01739 metB R02408
L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine
L-cystine thiocysteine-lyase (deaminating; pyruvate-forming)
Sws_02998 K01739 metB R02508
Cystathionine + Succinate <=> O-Succinyl-L-homoserine + L-Cysteine
Sws_02998 K01739 metB R03217
O-Acetyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Acetate
O-acetyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02998 K01739 metB R03260
O-Succinyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Succinate
O-succinyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02998 K01739 metB R04770
L-Selenomethionine + H2O <=> Methaneselenol + Ammonia + 2-Oxobutanoate
selenomethionine methanethiol-lyase (deaminating)
Sws_02998 K01739 metB R04941
L-Selenocystathionine + H2O <=> Selenohomocysteine + Ammonia + Pyruvate
selenocystathionine L-homocysteine-lyase (deaminating)
Sws_02998 K01739 metB R04944
O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate
O-phosphorylhomoserine:selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-phosphorylhomoserine phosphate-lyase (adding selenocysteine)
Sws_02998 K01739 metB R04945
O-Acetyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Acetate
O-acetylhomoserine succinate-lyase (adding cysteine)
Sws_02998 K01739 metB R04946
O-Succinyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Succinate
O4-succinyl-L-homoserine:L-selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding selenocysteine)
Sws_02999 K01739 metB R00782
L-Cysteine + H2O <=> Hydrogen sulfide + Pyruvate + Ammonia
L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming)
Sws_02999 K01739 metB R00999
O-Succinyl-L-homoserine + H2O <=> 2-Oxobutanoate + Succinate + Ammonia
O-succinyl-L-homoserine succinate-lyase (deaminating; 2-oxobutanoate-forming)
Sws_02999 K01739 metB R01286
L-Cystathionine + H2O <=> L-Homocysteine + Ammonia + Pyruvate
L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)
Sws_02999 K01739 metB R01288
O-Succinyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Succinate
O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide)
Sws_02999 K01739 metB R02408
L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine
L-cystine thiocysteine-lyase (deaminating; pyruvate-forming)
Sws_02999 K01739 metB R02508
Cystathionine + Succinate <=> O-Succinyl-L-homoserine + L-Cysteine
Sws_02999 K01739 metB R03217
O-Acetyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Acetate
O-acetyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02999 K01739 metB R03260
O-Succinyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Succinate
O-succinyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02999 K01739 metB R04941
L-Selenocystathionine + H2O <=> Selenohomocysteine + Ammonia + Pyruvate
selenocystathionine L-homocysteine-lyase (deaminating)
Sws_02999 K01739 metB R04944
O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate
O-phosphorylhomoserine:selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-phosphorylhomoserine phosphate-lyase (adding selenocysteine)
Sws_02999 K01739 metB R04945
O-Acetyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Acetate
O-acetylhomoserine succinate-lyase (adding cysteine)
Sws_02999 K01739 metB R04946
O-Succinyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Succinate
O4-succinyl-L-homoserine:L-selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding selenocysteine)
Sulfur metabolismMetabolism; Energy metabolism3 genes · 29 rxns
Sws_02997 K01738 cysK R00897
O-Acetyl-L-serine + Hydrogen sulfide <=> L-Cysteine + Acetate
O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase; O3-acetyl-L-serine acetate-lyase (adding hydrogen sulfide)
Sws_02997 K01738 cysK R03601
O-Acetyl-L-serine + Hydrogen selenide <=> L-Selenocysteine + Acetate
O3-acetyl-L-serine acetate-lyase (adding hydrogen sulfide)
Sws_02997 K01738 cysK R04859
O-Acetyl-L-serine + Thiosulfate + Thioredoxin + H+ <=> L-Cysteine + Sulfite + Thioredoxin disulfide + Acetate
O3-acetyl-L-serine:thiosulfate 2-amino-2-carboxyethyltransferase (reducing, L-cysteine-forming); O3-acetyl-L-serine acetate-lyase (thiosulfate-reducing, L-cysteine-forming)
Sws_02998 K01739 metB R00654
L-Methionine + H2O <=> Methanethiol + Ammonia + 2-Oxobutanoate
L-methionine methanethiol-lyase (deaminating;2-oxobutanoate-forming)
Sws_02998 K01739 metB R00782
L-Cysteine + H2O <=> Hydrogen sulfide + Pyruvate + Ammonia
L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming)
Sws_02998 K01739 metB R00999
O-Succinyl-L-homoserine + H2O <=> 2-Oxobutanoate + Succinate + Ammonia
O-succinyl-L-homoserine succinate-lyase (deaminating; 2-oxobutanoate-forming)
Sws_02998 K01739 metB R01286
L-Cystathionine + H2O <=> L-Homocysteine + Ammonia + Pyruvate
L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)
Sws_02998 K01739 metB R01288
O-Succinyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Succinate
O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide)
Sws_02998 K01739 metB R02408
L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine
L-cystine thiocysteine-lyase (deaminating; pyruvate-forming)
Sws_02998 K01739 metB R02508
Cystathionine + Succinate <=> O-Succinyl-L-homoserine + L-Cysteine
Sws_02998 K01739 metB R03217
O-Acetyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Acetate
O-acetyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02998 K01739 metB R03260
O-Succinyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Succinate
O-succinyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02998 K01739 metB R04770
L-Selenomethionine + H2O <=> Methaneselenol + Ammonia + 2-Oxobutanoate
selenomethionine methanethiol-lyase (deaminating)
Sws_02998 K01739 metB R04941
L-Selenocystathionine + H2O <=> Selenohomocysteine + Ammonia + Pyruvate
selenocystathionine L-homocysteine-lyase (deaminating)
Sws_02998 K01739 metB R04944
O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate
O-phosphorylhomoserine:selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-phosphorylhomoserine phosphate-lyase (adding selenocysteine)
Sws_02998 K01739 metB R04945
O-Acetyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Acetate
O-acetylhomoserine succinate-lyase (adding cysteine)
Sws_02998 K01739 metB R04946
O-Succinyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Succinate
O4-succinyl-L-homoserine:L-selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding selenocysteine)
Sws_02999 K01739 metB R00782
L-Cysteine + H2O <=> Hydrogen sulfide + Pyruvate + Ammonia
L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming)
Sws_02999 K01739 metB R00999
O-Succinyl-L-homoserine + H2O <=> 2-Oxobutanoate + Succinate + Ammonia
O-succinyl-L-homoserine succinate-lyase (deaminating; 2-oxobutanoate-forming)
Sws_02999 K01739 metB R01286
L-Cystathionine + H2O <=> L-Homocysteine + Ammonia + Pyruvate
L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)
Sws_02999 K01739 metB R01288
O-Succinyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Succinate
O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide)
Sws_02999 K01739 metB R02408
L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine
L-cystine thiocysteine-lyase (deaminating; pyruvate-forming)
Sws_02999 K01739 metB R02508
Cystathionine + Succinate <=> O-Succinyl-L-homoserine + L-Cysteine
Sws_02999 K01739 metB R03217
O-Acetyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Acetate
O-acetyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02999 K01739 metB R03260
O-Succinyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Succinate
O-succinyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02999 K01739 metB R04941
L-Selenocystathionine + H2O <=> Selenohomocysteine + Ammonia + Pyruvate
selenocystathionine L-homocysteine-lyase (deaminating)
Sws_02999 K01739 metB R04944
O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate
O-phosphorylhomoserine:selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-phosphorylhomoserine phosphate-lyase (adding selenocysteine)
Sws_02999 K01739 metB R04945
O-Acetyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Acetate
O-acetylhomoserine succinate-lyase (adding cysteine)
Sws_02999 K01739 metB R04946
O-Succinyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Succinate
O4-succinyl-L-homoserine:L-selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding selenocysteine)
Selenocompound metabolismMetabolism; Metabolism of other amino acids2 genes · 26 rxns
Sws_02998 K01739 metB R00654
L-Methionine + H2O <=> Methanethiol + Ammonia + 2-Oxobutanoate
L-methionine methanethiol-lyase (deaminating;2-oxobutanoate-forming)
Sws_02998 K01739 metB R00782
L-Cysteine + H2O <=> Hydrogen sulfide + Pyruvate + Ammonia
L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming)
Sws_02998 K01739 metB R00999
O-Succinyl-L-homoserine + H2O <=> 2-Oxobutanoate + Succinate + Ammonia
O-succinyl-L-homoserine succinate-lyase (deaminating; 2-oxobutanoate-forming)
Sws_02998 K01739 metB R01286
L-Cystathionine + H2O <=> L-Homocysteine + Ammonia + Pyruvate
L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)
Sws_02998 K01739 metB R01288
O-Succinyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Succinate
O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide)
Sws_02998 K01739 metB R02408
L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine
L-cystine thiocysteine-lyase (deaminating; pyruvate-forming)
Sws_02998 K01739 metB R02508
Cystathionine + Succinate <=> O-Succinyl-L-homoserine + L-Cysteine
Sws_02998 K01739 metB R03217
O-Acetyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Acetate
O-acetyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02998 K01739 metB R03260
O-Succinyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Succinate
O-succinyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02998 K01739 metB R04770
L-Selenomethionine + H2O <=> Methaneselenol + Ammonia + 2-Oxobutanoate
selenomethionine methanethiol-lyase (deaminating)
Sws_02998 K01739 metB R04941
L-Selenocystathionine + H2O <=> Selenohomocysteine + Ammonia + Pyruvate
selenocystathionine L-homocysteine-lyase (deaminating)
Sws_02998 K01739 metB R04944
O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate
O-phosphorylhomoserine:selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-phosphorylhomoserine phosphate-lyase (adding selenocysteine)
Sws_02998 K01739 metB R04945
O-Acetyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Acetate
O-acetylhomoserine succinate-lyase (adding cysteine)
Sws_02998 K01739 metB R04946
O-Succinyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Succinate
O4-succinyl-L-homoserine:L-selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding selenocysteine)
Sws_02999 K01739 metB R00782
L-Cysteine + H2O <=> Hydrogen sulfide + Pyruvate + Ammonia
L-cysteine hydrogen-sulfide-lyase (deaminating; pyruvate-forming)
Sws_02999 K01739 metB R00999
O-Succinyl-L-homoserine + H2O <=> 2-Oxobutanoate + Succinate + Ammonia
O-succinyl-L-homoserine succinate-lyase (deaminating; 2-oxobutanoate-forming)
Sws_02999 K01739 metB R01286
L-Cystathionine + H2O <=> L-Homocysteine + Ammonia + Pyruvate
L-cystathionine L-homocysteine-lyase (deaminating; pyruvate-forming)
Sws_02999 K01739 metB R01288
O-Succinyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Succinate
O4-succinyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding hydrogen sulfide)
Sws_02999 K01739 metB R02408
L-Cystine + H2O <=> Pyruvate + Ammonia + Thiocysteine
L-cystine thiocysteine-lyase (deaminating; pyruvate-forming)
Sws_02999 K01739 metB R02508
Cystathionine + Succinate <=> O-Succinyl-L-homoserine + L-Cysteine
Sws_02999 K01739 metB R03217
O-Acetyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Acetate
O-acetyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02999 K01739 metB R03260
O-Succinyl-L-homoserine + L-Cysteine <=> L-Cystathionine + Succinate
O-succinyl-L-homoserine succinate-lyase (adding cysteine)
Sws_02999 K01739 metB R04941
L-Selenocystathionine + H2O <=> Selenohomocysteine + Ammonia + Pyruvate
selenocystathionine L-homocysteine-lyase (deaminating)
Sws_02999 K01739 metB R04944
O-Phosphorylhomoserine + L-Selenocysteine <=> L-Selenocystathionine + Orthophosphate
O-phosphorylhomoserine:selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-phosphorylhomoserine phosphate-lyase (adding selenocysteine)
Sws_02999 K01739 metB R04945
O-Acetyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Acetate
O-acetylhomoserine succinate-lyase (adding cysteine)
Sws_02999 K01739 metB R04946
O-Succinyl-L-homoserine + L-Selenocysteine <=> L-Selenocystathionine + Succinate
O4-succinyl-L-homoserine:L-selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding selenocysteine)

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 3 genes
Sws_02997 Sws_02998 Sws_02999
Biosynthesis of secondary metabolites 3 genes
Sws_02997 Sws_02998 Sws_02999
Map 01130 3 genes
Sws_02997 Sws_02998 Sws_02999
Biosynthesis of amino acids 3 genes
Sws_02997 Sws_02998 Sws_02999
Microbial metabolism in diverse environments 1 genes
Sws_02997
Carbon metabolism 1 genes
Sws_02997

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Sws_02997 cysteine synthase A K01738 cysK 2.5.1.47 R00897,R03601,R04859
Sws_02998 trans-sulfuration enzyme family protein K01739 metB; K01760 metC; K01761 E4.4.1.11 2.5.1.48,4.4.1.11,4.4.1.8 R00654,R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946
Sws_02999 trans-sulfuration enzyme family protein K01739 metB; K01760 metC 2.5.1.48,4.4.1.8 R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946
Sws_03000 RrF2 family transcriptional regulator — — —
↑ Top




v1.00 @copyright 2026 UCLA