Reaction Activity

◀ domain architecture · operons · ❔ guide

Operon NZ_BBCE01000012.1:70,730–73,230

Syntrophomonas palmitatica JCM14374 Spalm · 2 genes

genes

KO-annotated

reactions

pathways

Activity by pathway — click to expand; ranked by genes involved

Cysteine and methionine metabolismMetabolism; Amino acid metabolism2 genes · 4 rxns

Spalm_01590 K00548 metH, MTR R00946

5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine

5-methyltetrahydrofolate:L-homocysteine S-methyltransferase

Spalm_01590 K00548 metH, MTR R09365

Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <=> L-Selenomethionine + Tetrahydropteroyltri-L-glutamate

5-methyltetrahydropteroyltri-L-glutamate:L-selenohomocysteine Se-methyltransferase

Spalm_01591 K00548 metH, MTR R00946

5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine

5-methyltetrahydrofolate:L-homocysteine S-methyltransferase

Spalm_01591 K00548 metH, MTR R09365

Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <=> L-Selenomethionine + Tetrahydropteroyltri-L-glutamate

5-methyltetrahydropteroyltri-L-glutamate:L-selenohomocysteine Se-methyltransferase

Selenocompound metabolismMetabolism; Metabolism of other amino acids2 genes · 4 rxns

Spalm_01590 K00548 metH, MTR R00946

5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine

5-methyltetrahydrofolate:L-homocysteine S-methyltransferase

Spalm_01590 K00548 metH, MTR R09365

Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <=> L-Selenomethionine + Tetrahydropteroyltri-L-glutamate

5-methyltetrahydropteroyltri-L-glutamate:L-selenohomocysteine Se-methyltransferase

Spalm_01591 K00548 metH, MTR R00946

5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine

5-methyltetrahydrofolate:L-homocysteine S-methyltransferase

Spalm_01591 K00548 metH, MTR R09365

Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <=> L-Selenomethionine + Tetrahydropteroyltri-L-glutamate

5-methyltetrahydropteroyltri-L-glutamate:L-selenohomocysteine Se-methyltransferase

One carbon pool by folateMetabolism; Metabolism of cofactors and vitamins2 genes · 4 rxns

Spalm_01590 K00548 metH, MTR R00946

5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine

5-methyltetrahydrofolate:L-homocysteine S-methyltransferase

Spalm_01590 K00548 metH, MTR R09365

Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <=> L-Selenomethionine + Tetrahydropteroyltri-L-glutamate

5-methyltetrahydropteroyltri-L-glutamate:L-selenohomocysteine Se-methyltransferase

Spalm_01591 K00548 metH, MTR R00946

5-Methyltetrahydrofolate + L-Homocysteine <=> Tetrahydrofolate + L-Methionine

5-methyltetrahydrofolate:L-homocysteine S-methyltransferase

Spalm_01591 K00548 metH, MTR R09365

Selenohomocysteine + 5-Methyltetrahydropteroyltri-L-glutamate <=> L-Selenomethionine + Tetrahydropteroyltri-L-glutamate

5-methyltetrahydropteroyltri-L-glutamate:L-selenohomocysteine Se-methyltransferase

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 2 genes

Spalm_01590 Spalm_01591

Biosynthesis of secondary metabolites 2 genes

Spalm_01590 Spalm_01591

Biosynthesis of amino acids 2 genes

Spalm_01590 Spalm_01591

Reaction network — compounds linked by the reactions these genes catalyse

show cofactors (H₂O, ATP, NAD⁺…) drag nodes · click an edge for the reaction

Genes

Locus	Product	KO	EC	Reactions
Spalm_01590	cobalamin-dependent protein	K00548 metH, MTR	2.1.1.13	R00946,R09365
Spalm_01591	homocysteine S-methyltransferase family protein	K00548 metH, MTR	2.1.1.13	R00946,R09365

Small Microbes Pathway Profiler

Operon NZ_BBCE01000012.1:70,730–73,230

Activity by pathway — click to expand; ranked by genes involved

Overview / global maps (every metabolic gene maps here)

Reaction network — compounds linked by the reactions these genes catalyse

Genes