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Nitrogen Fixation CANT-Hyd
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◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_CGIH01000012.1:11,400–17,289

Syntrophomonas zehnderi OL-4 Szehn · 4 genes
4
genes
3
KO-annotated
5
reactions
5
pathways

Activity by pathway — click to expand; ranked by genes involved

Other carbon fixation pathwaysMetabolism; Energy metabolism2 genes · 5 rxns
Szeh_00808 K01681 ACO R01324
Citrate <=> Isocitrate
citrate hydroxymutase
Szeh_00808 K01681 ACO R01325
Citrate <=> cis-Aconitate + H2O
citrate hydro-lyase (cis-aconitate-forming)
Szeh_00808 K01681 ACO R01900
Isocitrate <=> cis-Aconitate + H2O
isocitrate hydro-lyase (cis-aconitate-forming)
Szeh_00809 K00297 metF, MTHFR R01224
5-Methyltetrahydrofolate + NADP+ <=> 5,10-Methylenetetrahydrofolate + NADPH + H+
5-methyltetrahydrofolate:NADP+ oxidoreductase
Szeh_00809 K00297 metF, MTHFR R07168
5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
5-methyltetrahydrofolate:NAD+ oxidoreductase
Citrate cycle (TCA cycle)Metabolism; Carbohydrate metabolism1 genes · 3 rxns
Szeh_00808 K01681 ACO R01324
Citrate <=> Isocitrate
citrate hydroxymutase
Szeh_00808 K01681 ACO R01325
Citrate <=> cis-Aconitate + H2O
citrate hydro-lyase (cis-aconitate-forming)
Szeh_00808 K01681 ACO R01900
Isocitrate <=> cis-Aconitate + H2O
isocitrate hydro-lyase (cis-aconitate-forming)
Glyoxylate and dicarboxylate metabolismMetabolism; Carbohydrate metabolism1 genes · 3 rxns
Szeh_00808 K01681 ACO R01324
Citrate <=> Isocitrate
citrate hydroxymutase
Szeh_00808 K01681 ACO R01325
Citrate <=> cis-Aconitate + H2O
citrate hydro-lyase (cis-aconitate-forming)
Szeh_00808 K01681 ACO R01900
Isocitrate <=> cis-Aconitate + H2O
isocitrate hydro-lyase (cis-aconitate-forming)
One carbon pool by folateMetabolism; Metabolism of cofactors and vitamins1 genes · 2 rxns
Szeh_00809 K00297 metF, MTHFR R01224
5-Methyltetrahydrofolate + NADP+ <=> 5,10-Methylenetetrahydrofolate + NADPH + H+
5-methyltetrahydrofolate:NADP+ oxidoreductase
Szeh_00809 K00297 metF, MTHFR R07168
5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
5-methyltetrahydrofolate:NAD+ oxidoreductase
Antifolate resistanceHuman Diseases; Drug resistance: antineoplastic1 genes · 2 rxns
Szeh_00809 K00297 metF, MTHFR R01224
5-Methyltetrahydrofolate + NADP+ <=> 5,10-Methylenetetrahydrofolate + NADPH + H+
5-methyltetrahydrofolate:NADP+ oxidoreductase
Szeh_00809 K00297 metF, MTHFR R07168
5-Methyltetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + NADH + H+
5-methyltetrahydrofolate:NAD+ oxidoreductase

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 2 genes
Szeh_00808 Szeh_00809
Microbial metabolism in diverse environments 2 genes
Szeh_00808 Szeh_00809
Carbon metabolism 2 genes
Szeh_00808 Szeh_00809
Biosynthesis of secondary metabolites 1 genes
Szeh_00808
Map 01130 1 genes
Szeh_00808
2-Oxocarboxylic acid metabolism 1 genes
Szeh_00808
Biosynthesis of amino acids 1 genes
Szeh_00808

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Szeh_00806 hypothetical protein — — —
Szeh_00807 DNA polymerase Y family protein K02346 dinB 2.7.7.7 —
Szeh_00808 hydratase K01681 ACO 4.2.1.3 R01324,R01325,R01900
Szeh_00809 methylenetetrahydrofolate reductase C-terminal domain-containing protein K00297 metF, MTHFR 1.5.1.20 R01224,R07168
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