Reaction Activity

◀ domain architecture · operons · ❔ guide

Operon NZ_CGIH01000040.1:24,661–29,716

Syntrophomonas zehnderi OL-4 Szehn · 4 genes

genes

KO-annotated

reactions

pathways

Activity by pathway — click to expand; ranked by genes involved

Purine metabolismMetabolism; Nucleotide metabolism2 genes · 10 rxns

Szeh_02296 K00760 hprT, hpt, HPRT1 R00190

AMP + Diphosphate <=> Adenine + 5-Phospho-alpha-D-ribose 1-diphosphate

AMP:diphosphate phospho-D-ribosyltransferase

Szeh_02296 K00760 hprT, hpt, HPRT1 R01132

IMP + Diphosphate <=> Hypoxanthine + 5-Phospho-alpha-D-ribose 1-diphosphate

IMP:diphosphate phospho-D-ribosyltransferase

Szeh_02296 K00760 hprT, hpt, HPRT1 R01229

GMP + Diphosphate <=> Guanine + 5-Phospho-alpha-D-ribose 1-diphosphate

GMP:diphosphate 5-phospho-alpha-D-ribosyltransferase

Szeh_02296 K00760 hprT, hpt, HPRT1 R02142

Xanthosine 5'-phosphate + Diphosphate <=> Xanthine + 5-Phospho-alpha-D-ribose 1-diphosphate

XMP:pyrophosphate phosphoribosyltransferase

Szeh_02296 K00760 hprT, hpt, HPRT1 R08237

6-Mercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioinosine-5'-monophosphate + Diphosphate

6-thioinosine 5'-monophosphate:diphosphate phospho-D-ribosyltransferase

Szeh_02296 K00760 hprT, hpt, HPRT1 R08238

6-Methylmercaptopurine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Methylthiopurine 5'-monophosphate ribonucleotide + Diphosphate

6-methylthiopurine 5'-monophosphate ribonucleotide:diphosphate phospho-D-ribosyltransferase

Szeh_02296 K00760 hprT, hpt, HPRT1 R08245

Thioguanine + 5-Phospho-alpha-D-ribose 1-diphosphate <=> 6-Thioguanosine monophosphate + Diphosphate

6-thioguanosine monophosphate:diphosphate phospho-D-ribosyltransferase

Szeh_02297 K01951 guaA, GMPS R01230

ATP + Xanthosine 5'-phosphate + Ammonia <=> AMP + Diphosphate + GMP

xanthosine-5'-phosphate:ammonia ligase (AMP-forming)

Szeh_02297 K01951 guaA, GMPS R01231

ATP + Xanthosine 5'-phosphate + L-Glutamine + H2O <=> AMP + Diphosphate + GMP + L-Glutamate

xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)

Szeh_02297 K01951 guaA, GMPS R08244

6-Thioxanthine 5'-monophosphate + ATP + L-Glutamine + H2O <=> 6-Thioguanosine monophosphate + AMP + Diphosphate + L-Glutamate

6-thioxanthine 5'-monophosphate:L-glutamine amido-ligase (AMP-forming)

Drug metabolism - other enzymesMetabolism; Xenobiotics biodegradation and metabolism2 genes · 10 rxns