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◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_CGIH01000047.1:37,738–41,775

Syntrophomonas zehnderi OL-4 Szehn · 4 genes
4
genes
4
KO-annotated
5
reactions
2
pathways

Activity by pathway — click to expand; ranked by genes involved

Purine metabolismMetabolism; Nucleotide metabolism4 genes · 7 rxns
Szeh_02473 K01588 purE R07405
5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole <=> 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole carboxymutase
Szeh_02474 K01756 purB, ADSL R01083
N6-(1,2-Dicarboxyethyl)-AMP <=> Fumarate + AMP
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)
Szeh_02474 K01756 purB, ADSL R04559
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole <=> Fumarate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
1-(5'-phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase
Szeh_02475 K01756 purB, ADSL R01083
N6-(1,2-Dicarboxyethyl)-AMP <=> Fumarate + AMP
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)
Szeh_02475 K01756 purB, ADSL R04559
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole <=> Fumarate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
1-(5'-phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase
Szeh_02475 K01756 purB, ADSL R04591
ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartate <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
1-(5-phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming)
Szeh_02476 K00764 purF, PPAT R01072
5-Phosphoribosylamine + Diphosphate + L-Glutamate <=> L-Glutamine + 5-Phospho-alpha-D-ribose 1-diphosphate + H2O
5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)
Alanine, aspartate and glutamate metabolismMetabolism; Amino acid metabolism3 genes · 6 rxns
Szeh_02474 K01756 purB, ADSL R01083
N6-(1,2-Dicarboxyethyl)-AMP <=> Fumarate + AMP
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)
Szeh_02474 K01756 purB, ADSL R04559
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole <=> Fumarate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
1-(5'-phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase
Szeh_02475 K01756 purB, ADSL R01083
N6-(1,2-Dicarboxyethyl)-AMP <=> Fumarate + AMP
N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)
Szeh_02475 K01756 purB, ADSL R04559
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole <=> Fumarate + 1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
1-(5'-phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase
Szeh_02475 K01756 purB, ADSL R04591
ATP + 1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate + L-Aspartate <=> ADP + Orthophosphate + 1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
1-(5-phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming)
Szeh_02476 K00764 purF, PPAT R01072
5-Phosphoribosylamine + Diphosphate + L-Glutamate <=> L-Glutamine + 5-Phospho-alpha-D-ribose 1-diphosphate + H2O
5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 4 genes
Szeh_02473 Szeh_02474 Szeh_02475 Szeh_02476
Biosynthesis of secondary metabolites 4 genes
Szeh_02473 Szeh_02474 Szeh_02475 Szeh_02476
Map 01130 4 genes
Szeh_02473 Szeh_02474 Szeh_02475 Szeh_02476

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Szeh_02473 5-(carboxyamino)imidazole ribonucleotide mutase K01588 purE 5.4.99.18 R07405
Szeh_02474 adenylosuccinate lyase K01756 purB, ADSL 4.3.2.2 R01083,R04559
Szeh_02475 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01756 purB, ADSL; K01923 purC 4.3.2.2,6.3.2.6 R01083,R04559,R04591
Szeh_02476 amidophosphoribosyltransferase K00764 purF, PPAT 2.4.2.14 R01072
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