Small Microbes Pathway Profiler

Domain Counts
Profiler Search and BLAST
CAZy ▾
CAZyme Browser CAzy - DBCAN (original) CAZyme protein counts Proteome Coverage Summary
Search ▾
Text search Domain display search
Pathways ▾
Nitrogen Fixation CANT-Hyd
UMAP
◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_CGIH01000032.1:73,950–75,553

Syntrophomonas zehnderi OL-4 Szehn · 2 genes
2
genes
2
KO-annotated
8
reactions
2
pathways

Activity by pathway — click to expand; ranked by genes involved

Valine, leucine and isoleucine biosynthesisMetabolism; Amino acid metabolism2 genes · 8 rxns
Szeh_01971 K00052 leuB, IMDH R00994
2-Oxobutanoate + CO2 + NADH + H+ <=> D-erythro-3-Methylmalate + NAD+
(2R,3S)-3-methylmalate:NAD+ oxidoreductase
Szeh_01971 K00052 leuB, IMDH R04426
(2R,3S)-3-Isopropylmalate + NAD+ <=> (2S)-2-Isopropyl-3-oxosuccinate + NADH + H+
(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase
Szeh_01971 K00052 leuB, IMDH R10052
(2R,3S)-3-Isopropylmalate + NAD+ <=> 4-Methyl-2-oxopentanoate + CO2 + NADH + H+
(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase
Szeh_01972 K01704 leuD, IPMI-S R03896
(R)-2-Methylmalate <=> 2-Methylmaleate + H2O
(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)
Szeh_01972 K01704 leuD, IPMI-S R03898
2-Methylmaleate + H2O <=> D-erythro-3-Methylmalate
2-methylmaleate hydratase; D-erythro-3-methylmalate hydro-lyase (2-methylmaleate-forming)
Szeh_01972 K01704 leuD, IPMI-S R03968
alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O
2-isopropylmalate hydro-lyase
Szeh_01972 K01704 leuD, IPMI-S R04001
(2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
3-isopropylmalate hydro-lyase
Szeh_01972 K01704 leuD, IPMI-S R10170
(2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate
(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)
C5-Branched dibasic acid metabolismMetabolism; Carbohydrate metabolism2 genes · 8 rxns
Szeh_01971 K00052 leuB, IMDH R00994
2-Oxobutanoate + CO2 + NADH + H+ <=> D-erythro-3-Methylmalate + NAD+
(2R,3S)-3-methylmalate:NAD+ oxidoreductase
Szeh_01971 K00052 leuB, IMDH R04426
(2R,3S)-3-Isopropylmalate + NAD+ <=> (2S)-2-Isopropyl-3-oxosuccinate + NADH + H+
(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase
Szeh_01971 K00052 leuB, IMDH R10052
(2R,3S)-3-Isopropylmalate + NAD+ <=> 4-Methyl-2-oxopentanoate + CO2 + NADH + H+
(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase
Szeh_01972 K01704 leuD, IPMI-S R03896
(R)-2-Methylmalate <=> 2-Methylmaleate + H2O
(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)
Szeh_01972 K01704 leuD, IPMI-S R03898
2-Methylmaleate + H2O <=> D-erythro-3-Methylmalate
2-methylmaleate hydratase; D-erythro-3-methylmalate hydro-lyase (2-methylmaleate-forming)
Szeh_01972 K01704 leuD, IPMI-S R03968
alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O
2-isopropylmalate hydro-lyase
Szeh_01972 K01704 leuD, IPMI-S R04001
(2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
3-isopropylmalate hydro-lyase
Szeh_01972 K01704 leuD, IPMI-S R10170
(2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate
(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 2 genes
Szeh_01971 Szeh_01972
Biosynthesis of secondary metabolites 2 genes
Szeh_01971 Szeh_01972
2-Oxocarboxylic acid metabolism 2 genes
Szeh_01971 Szeh_01972
Biosynthesis of amino acids 2 genes
Szeh_01971 Szeh_01972

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Szeh_01971 3-isopropylmalate dehydrogenase K00052 leuB, IMDH 1.1.1.85 R00994,R04426,R10052
Szeh_01972 3-isopropylmalate dehydratase small subunit K01704 leuD, IPMI-S 4.2.1.33,4.2.1.35 R03896,R03898,R03968,R04001,R10170
↑ Top




v1.00 @copyright 2026 UCLA