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◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_CGIH01000026.1:151,092–156,565

Syntrophomonas zehnderi OL-4 Szehn · 6 genes
6
genes
5
KO-annotated
7
reactions
5
pathways

Activity by pathway — click to expand; ranked by genes involved

Cysteine and methionine metabolismMetabolism; Amino acid metabolism2 genes · 3 rxns
Szeh_01387 K00651 metA R01777
Succinyl-CoA + L-Homoserine <=> CoA + O-Succinyl-L-homoserine
succinyl-CoA:L-homoserine O-succinyltransferase
Szeh_01388 K01740 metY R01287
O-Acetyl-L-homoserine + Hydrogen sulfide <=> L-Homocysteine + Acetate
O-acetyl-L-homoserine:hydrogen sulfide S-(3-amino-3-carboxypropyl)transferase; O-acetyl-L-homoserine acetate-lyase (adding hydrogen sulfide)
Szeh_01388 K01740 metY R04859
O-Acetyl-L-serine + Thiosulfate + Thioredoxin + H+ <=> L-Cysteine + Sulfite + Thioredoxin disulfide + Acetate
O3-acetyl-L-serine:thiosulfate 2-amino-2-carboxyethyltransferase (reducing, L-cysteine-forming); O3-acetyl-L-serine acetate-lyase (thiosulfate-reducing, L-cysteine-forming)
Sulfur metabolismMetabolism; Energy metabolism1 genes · 1 rxns
Szeh_01387 K00651 metA R01777
Succinyl-CoA + L-Homoserine <=> CoA + O-Succinyl-L-homoserine
succinyl-CoA:L-homoserine O-succinyltransferase
Thiamine metabolismMetabolism; Metabolism of cofactors and vitamins1 genes · 3 rxns
Szeh_01390 K04487 iscS, NFS1 R07460
[Enzyme]-cysteine + L-Cysteine <=> [Enzyme]-S-sulfanylcysteine + L-Alanine
L-cysteine:[enzyme]-cysteine sulfurtransferase
Szeh_01390 K04487 iscS, NFS1 R11528
L-Cysteine + [Protein]-L-cysteine <=> L-Alanine + [Protein]-S-sulfanyl-L-cysteine
L-cysteine:sulfur-acceptor sulfurtransferase
Szeh_01390 K04487 iscS, NFS1 R11529
[Enzyme]-S-sulfanylcysteine + [Protein]-L-cysteine <=> [Enzyme]-cysteine + [Protein]-S-sulfanyl-L-cysteine
[enzyme]-S-sulfanylcysteine:sulfur-acceptor sulfurtransferase
Sulfur relay systemGenetic Information Processing; Folding, sorting and degradation1 genes · 3 rxns
Szeh_01390 K04487 iscS, NFS1 R07460
[Enzyme]-cysteine + L-Cysteine <=> [Enzyme]-S-sulfanylcysteine + L-Alanine
L-cysteine:[enzyme]-cysteine sulfurtransferase
Szeh_01390 K04487 iscS, NFS1 R11528
L-Cysteine + [Protein]-L-cysteine <=> L-Alanine + [Protein]-S-sulfanyl-L-cysteine
L-cysteine:sulfur-acceptor sulfurtransferase
Szeh_01390 K04487 iscS, NFS1 R11529
[Enzyme]-S-sulfanylcysteine + [Protein]-L-cysteine <=> [Enzyme]-cysteine + [Protein]-S-sulfanyl-L-cysteine
[enzyme]-S-sulfanylcysteine:sulfur-acceptor sulfurtransferase
Nicotinate and nicotinamide metabolismMetabolism; Metabolism of cofactors and vitamins1 genes · 1 rxns
Szeh_01391 K03517 nadA R04292
Quinolinate + 2 H2O + Orthophosphate <=> Iminoaspartate + Glycerone phosphate
glycerone phosphate:iminosuccinate alkyltransferase (cyclizing)

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 4 genes
Szeh_01387 Szeh_01388 Szeh_01390 Szeh_01391
Biosynthesis of secondary metabolites 1 genes
Szeh_01387
Biosynthesis of amino acids 1 genes
Szeh_01387

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Szeh_01387 homoserine O-acetyltransferase MetA K00651 metA 2.3.1.46 R01777
Szeh_01388 homocysteine synthase K01740 metY 2.5.1.49 R01287,R04859
Szeh_01389 Fe-S cluster assembly scaffold protein NifU K04488 iscU, nifU — —
Szeh_01390 cysteine desulfurase NifS K04487 iscS, NFS1 2.8.1.7 R07460,R11528,R11529
Szeh_01391 quinolinate synthase NadA K03517 nadA 2.5.1.72 R04292
Szeh_01392 MOSC domain-containing protein — — —
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