Reaction Activity

Operon NZ_CGIH01000047.1:48,393–52,418

Syntrophomonas zehnderi OL-4 Szehn · 5 genes

genes

KO-annotated

reactions

pathways

Histidine metabolismMetabolism; Amino acid metabolism4 genes · 6 rxns

Szeh_02484 K02502 hisZ R01071

1-(5-Phospho-D-ribosyl)-ATP + Diphosphate <=> ATP + 5-Phospho-alpha-D-ribose 1-diphosphate

1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase

Szeh_02485 K00765 hisG R01071

1-(5-Phospho-D-ribosyl)-ATP + Diphosphate <=> ATP + 5-Phospho-alpha-D-ribose 1-diphosphate

1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-alpha-D-ribosyl-transferase

Szeh_02486 K00013 hisD R01158

L-Histidinol + 2 NAD+ + H2O <=> L-Histidine + 2 NADH + 2 H+

L-histidinol:NAD+ oxidoreductase

Szeh_02486 K00013 hisD R01163

L-Histidinal + H2O + NAD+ <=> L-Histidine + NADH + H+

L-histidinal:NAD+ oxidoreductase

Szeh_02486 K00013 hisD R03012

L-Histidinol + NAD+ <=> L-Histidinal + NADH + H+

L-histidinol:NAD+ oxidoreductase

Szeh_02487 K01693 hisB R03457

D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate <=> 3-(Imidazol-4-yl)-2-oxopropyl phosphate + H2O

D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate hydro-lyase

Metabolic pathways 4 genes

Szeh_02484 Szeh_02485 Szeh_02486 Szeh_02487

Biosynthesis of secondary metabolites 4 genes

Szeh_02484 Szeh_02485 Szeh_02486 Szeh_02487

Biosynthesis of amino acids 4 genes

Szeh_02484 Szeh_02485 Szeh_02486 Szeh_02487

show cofactors (H₂O, ATP, NAD⁺…) drag nodes · click an edge for the reaction

Locus	Product	KO	EC	Reactions
Szeh_02483	YerC/YecD family TrpR-related protein	—	—	—
Szeh_02484	ATP phosphoribosyltransferase regulatory subunit	K02502 hisZ	—	R01071
Szeh_02485	ATP phosphoribosyltransferase	K00765 hisG; K02502 hisZ	2.4.2.17	R01071
Szeh_02486	histidinol dehydrogenase	K00013 hisD	1.1.1.23	R01158,R01163,R03012
Szeh_02487	imidazoleglycerol-phosphate dehydratase HisB	K01693 hisB	4.2.1.19	R03457