Reaction Activity

Operon NC_008346.1:786,234–788,946

Syntrophomonas wolfei subsp. wolfei Goettingen · 2 genes

genes

KO-annotated

reactions

pathways

Porphyrin metabolismMetabolism; Metabolism of cofactors and vitamins1 genes · 4 rxns

Swg_00682 K02302 cysG R02864

Siroheme + 2 H+ <=> Fe2+ + Sirohydrochlorin

S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase

Swg_00682 K02302 cysG R03165

Hydroxymethylbilane <=> Uroporphyrinogen III + H2O

hydroxymethylbilane hydro-lyase(cyclizing)

Swg_00682 K02302 cysG R03194

2 S-Adenosyl-L-methionine + Uroporphyrinogen III <=> 2 S-Adenosyl-L-homocysteine + Precorrin 2

S-adenosyl-L-methionine:uroporphyrinogen-III C-methyltransferase

Swg_00682 K02302 cysG R03947

Precorrin 2 + NAD+ <=> Sirohydrochlorin + NADH + H+

S-adenosyl-L-methionine:uroporphyrin-III C-methyltransferase

Metabolic pathways 1 genes

Swg_00682

Biosynthesis of secondary metabolites 1 genes

Swg_00682

Microbial metabolism in diverse environments 1 genes

Swg_00682

show cofactors (H₂O, ATP, NAD⁺…) drag nodes · click an edge for the reaction

Locus	Product	KO	EC	Reactions
Swg_00682	uroporphyrinogen-III C-methyltransferase	K02302 cysG; K02303 cobA; K13542 cobA-hemD	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	R02864,R03165,R03194,R03947
Swg_00683	radical SAM/SPASM domain-containing protein	K22226 ahbC	—	—