Small Microbes Pathway Profiler

Domain Counts
Profiler Search and BLAST
CAZy ▾
CAZyme Browser CAzy - DBCAN (original) CAZyme protein counts Proteome Coverage Summary
Search ▾
Text search Domain display search
Pathways ▾
Nitrogen Fixation CANT-Hyd
UMAP
◀ domain architecture  ·  operons  ·  ❔ guide

Operon NC_008346.1:896,136–902,035

Syntrophomonas wolfei subsp. wolfei Goettingen · 5 genes
5
genes
4
KO-annotated
11
reactions
14
pathways

Activity by pathway — click to expand; ranked by genes involved

Butanoate metabolismMetabolism; Carbohydrate metabolism4 genes · 11 rxns
Swg_00785 K00248 ACADS, bcd R01175
Butanoyl-CoA + FAD <=> FADH2 + Crotonoyl-CoA
butanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R01178
Short-chain acyl-CoA + Electron-transferring flavoprotein <=> Short-chain trans-2,3-dehydroacyl-CoA + Reduced electron-transferring flavoprotein
short-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R02661
2-Methylpropanoyl-CoA + Acceptor <=> 2-Methylprop-2-enoyl-CoA + Reduced acceptor
2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R03172
(S)-2-Methylbutanoyl-CoA + Acceptor <=> 2-Methylbut-2-enoyl-CoA + Reduced acceptor
(S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R04751
Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
hexanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Swg_00787 K01715 crt R03026
(S)-3-Hydroxybutanoyl-CoA <=> Crotonoyl-CoA + H2O
(S)-3-hydroxybutanoyl-CoA hydro-lyase
Swg_00788 K00074 paaH, hbd, fadB, mmgB R01976
(S)-3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Swg_00788 K00074 paaH, hbd, fadB, mmgB R05576
3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Swg_00788 K00074 paaH, hbd, fadB, mmgB R06941
(3S)-3-Hydroxyadipyl-CoA + NAD+ <=> 3-Oxoadipyl-CoA + NADH + H+
(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase
Fatty acid degradationMetabolism; Lipid metabolism2 genes · 7 rxns
Swg_00785 K00248 ACADS, bcd R01175
Butanoyl-CoA + FAD <=> FADH2 + Crotonoyl-CoA
butanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R01178
Short-chain acyl-CoA + Electron-transferring flavoprotein <=> Short-chain trans-2,3-dehydroacyl-CoA + Reduced electron-transferring flavoprotein
short-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R02661
2-Methylpropanoyl-CoA + Acceptor <=> 2-Methylprop-2-enoyl-CoA + Reduced acceptor
2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R03172
(S)-2-Methylbutanoyl-CoA + Acceptor <=> 2-Methylbut-2-enoyl-CoA + Reduced acceptor
(S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R04751
Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
hexanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Valine, leucine and isoleucine degradationMetabolism; Amino acid metabolism2 genes · 7 rxns
Swg_00785 K00248 ACADS, bcd R01175
Butanoyl-CoA + FAD <=> FADH2 + Crotonoyl-CoA
butanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R01178
Short-chain acyl-CoA + Electron-transferring flavoprotein <=> Short-chain trans-2,3-dehydroacyl-CoA + Reduced electron-transferring flavoprotein
short-chain acyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R02661
2-Methylpropanoyl-CoA + Acceptor <=> 2-Methylprop-2-enoyl-CoA + Reduced acceptor
2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R03172
(S)-2-Methylbutanoyl-CoA + Acceptor <=> 2-Methylbut-2-enoyl-CoA + Reduced acceptor
(S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase
Swg_00785 K00248 ACADS, bcd R04751
Hexanoyl-CoA + FAD <=> trans-Hex-2-enoyl-CoA + FADH2
hexanoyl-CoA:electron-transfer flavoprotein 2,3-oxidoreductase
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Benzoate degradationMetabolism; Xenobiotics biodegradation and metabolism2 genes · 5 rxns
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Swg_00788 K00074 paaH, hbd, fadB, mmgB R01976
(S)-3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Swg_00788 K00074 paaH, hbd, fadB, mmgB R05576
3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Swg_00788 K00074 paaH, hbd, fadB, mmgB R06941
(3S)-3-Hydroxyadipyl-CoA + NAD+ <=> 3-Oxoadipyl-CoA + NADH + H+
(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase
Pathway 000721 genes · 2 rxns
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Lysine degradationMetabolism; Amino acid metabolism1 genes · 2 rxns
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Tryptophan metabolismMetabolism; Amino acid metabolism1 genes · 2 rxns
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Pyruvate metabolismMetabolism; Carbohydrate metabolism1 genes · 2 rxns
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Glyoxylate and dicarboxylate metabolismMetabolism; Carbohydrate metabolism1 genes · 2 rxns
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Propanoate metabolismMetabolism; Carbohydrate metabolism1 genes · 2 rxns
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Other carbon fixation pathwaysMetabolism; Energy metabolism1 genes · 2 rxns
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Terpenoid backbone biosynthesisMetabolism; Metabolism of terpenoids and polyketides1 genes · 2 rxns
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Two-component systemEnvironmental Information Processing; Signal transduction1 genes · 2 rxns
Swg_00786 K00626 ACAT, atoB R00238
2 Acetyl-CoA <=> CoA + Acetoacetyl-CoA
acetyl-CoA:acetyl-CoA C-acetyltransferase
Swg_00786 K00626 ACAT, atoB R01177
Acetyl-CoA + Butanoyl-CoA <=> CoA + 3-Oxohexanoyl-CoA
butanoyl-CoA:acetyl-CoA C-butanoyltransferase
Phenylalanine metabolismMetabolism; Amino acid metabolism1 genes · 3 rxns
Swg_00788 K00074 paaH, hbd, fadB, mmgB R01976
(S)-3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Swg_00788 K00074 paaH, hbd, fadB, mmgB R05576
3-Hydroxybutanoyl-CoA + NADP+ <=> Acetoacetyl-CoA + NADPH + H+
(S)-3-hydroxybutanoyl-CoA:NADP+ oxidoreductase
Swg_00788 K00074 paaH, hbd, fadB, mmgB R06941
(3S)-3-Hydroxyadipyl-CoA + NAD+ <=> 3-Oxoadipyl-CoA + NADH + H+
(S)-3-hydroxyacyl-CoA:NAD+ oxidoreductase

Overview / global maps (every metabolic gene maps here)

Carbon metabolism 3 genes
Swg_00785 Swg_00786 Swg_00787
Metabolic pathways 3 genes
Swg_00785 Swg_00786 Swg_00788
Microbial metabolism in diverse environments 3 genes
Swg_00785 Swg_00786 Swg_00788
Fatty acid metabolism 2 genes
Swg_00785 Swg_00786
Biosynthesis of secondary metabolites 2 genes
Swg_00785 Swg_00786
Map 01130 1 genes
Swg_00786

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Swg_00784 acetyl-CoA hydrolase/transferase family protein — — —
Swg_00785 acyl-CoA dehydrogenase family protein K00248 ACADS, bcd 1.3.8.1 R01175,R01178,R02661,R03172,R04751
Swg_00786 thiolase family protein K00626 ACAT, atoB 2.3.1.9 R00238,R01177
Swg_00787 enoyl-CoA hydratase-related protein K01715 crt 4.2.1.17 R03026
Swg_00788 3-hydroxyacyl-CoA dehydrogenase family protein K00074 paaH, hbd, fadB, mmgB 1.1.1.157 R01976,R05576,R06941
↑ Top




v1.00 @copyright 2026 UCLA