Reaction Activity

Operon NC_008346.1:1,475,069–1,477,736

Syntrophomonas wolfei subsp. wolfei Goettingen · 4 genes

genes

KO-annotated

reactions

pathways

Pyrimidine metabolismMetabolism; Nucleotide metabolism3 genes · 3 rxns

Swg_01289 K00762 pyrE R01870

Orotidine 5'-phosphate + Diphosphate <=> Orotate + 5-Phospho-alpha-D-ribose 1-diphosphate

orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase

Swg_01290 K01591 pyrF R00965

Orotidine 5'-phosphate <=> UMP + CO2

orotidine-5'-phosphate carboxy-lyase (UMP-forming)

Swg_01291 K17828 pyrDI R01869

(S)-Dihydroorotate + NAD+ <=> Orotate + H+ + NADH

(S)-dihydroorotate:NAD+ oxidoreductase

Metabolic pathways 3 genes

Swg_01289 Swg_01290 Swg_01291

show cofactors (H₂O, ATP, NAD⁺…) drag nodes · click an edge for the reaction

Locus	Product	KO	EC	Reactions
Swg_01288	hypothetical protein	—	—	—
Swg_01289	orotate phosphoribosyltransferase	K00762 pyrE	2.4.2.10	R01870
Swg_01290	orotidine-5'-phosphate decarboxylase	K01591 pyrF	4.1.1.23	R00965
Swg_01291	dihydroorotate dehydrogenase	K17828 pyrDI	1.3.1.14	R01869