Reaction Activity

Operon NZ_CM161534.1:1,617,116–1,619,784

Syntrophomonas wolfei methylbutyratica 4J5 · 4 genes

genes

KO-annotated

reactions

pathways

Pyrimidine metabolismMetabolism; Nucleotide metabolism3 genes · 3 rxns

Swm_01432 K00762 pyrE R01870

Orotidine 5'-phosphate + Diphosphate <=> Orotate + 5-Phospho-alpha-D-ribose 1-diphosphate

orotidine-5'-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase

Swm_01433 K01591 pyrF R00965

Orotidine 5'-phosphate <=> UMP + CO2

orotidine-5'-phosphate carboxy-lyase (UMP-forming)

Swm_01434 K17828 pyrDI R01869

(S)-Dihydroorotate + NAD+ <=> Orotate + H+ + NADH

(S)-dihydroorotate:NAD+ oxidoreductase

Metabolic pathways 3 genes

Swm_01432 Swm_01433 Swm_01434

show cofactors (H₂O, ATP, NAD⁺…) drag nodes · click an edge for the reaction

Locus	Product	KO	EC	Reactions
Swm_01431	hypothetical protein	—	—	—
Swm_01432	orotate phosphoribosyltransferase	K00762 pyrE	2.4.2.10	R01870
Swm_01433	orotidine-5'-phosphate decarboxylase	K01591 pyrF	4.1.1.23	R00965
Swm_01434	dihydroorotate dehydrogenase	K17828 pyrDI	1.3.1.14	R01869