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◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_CM161534.1:2,521,661–2,524,818

Syntrophomonas wolfei methylbutyratica 4J5 · 3 genes
3
genes
3
KO-annotated
2
reactions
2
pathways

Activity by pathway — click to expand; ranked by genes involved

Glycine, serine and threonine metabolismMetabolism; Amino acid metabolism3 genes · 5 rxns
Swm_02289 K00283 gcvPB R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Swm_02289 K00283 gcvPB R03425
Glycine + Lipoylprotein <=> [Protein]-S8-aminomethyldihydrolipoyllysine + CO2
glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)
Swm_02290 K00282 gcvPA R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Swm_02290 K00282 gcvPA R03425
Glycine + Lipoylprotein <=> [Protein]-S8-aminomethyldihydrolipoyllysine + CO2
glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)
Swm_02291 K02437 gcvH, GCSH R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Glyoxylate and dicarboxylate metabolismMetabolism; Carbohydrate metabolism3 genes · 5 rxns
Swm_02289 K00283 gcvPB R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Swm_02289 K00283 gcvPB R03425
Glycine + Lipoylprotein <=> [Protein]-S8-aminomethyldihydrolipoyllysine + CO2
glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)
Swm_02290 K00282 gcvPA R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system
Swm_02290 K00282 gcvPA R03425
Glycine + Lipoylprotein <=> [Protein]-S8-aminomethyldihydrolipoyllysine + CO2
glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)
Swm_02291 K02437 gcvH, GCSH R01221
Glycine + Tetrahydrofolate + NAD+ <=> 5,10-Methylenetetrahydrofolate + Ammonia + CO2 + NADH + H+
glycine:NAD+ 2-oxidoreductase (tetrahydrofolate-methylene-adding); glycine cleavage system

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 3 genes
Swm_02289 Swm_02290 Swm_02291
Biosynthesis of secondary metabolites 3 genes
Swm_02289 Swm_02290 Swm_02291
Map 01130 3 genes
Swm_02289 Swm_02290 Swm_02291
Carbon metabolism 3 genes
Swm_02289 Swm_02290 Swm_02291

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Swm_02289 aminomethyl-transferring glycine dehydrogenase subunit GcvPB K00283 gcvPB 1.4.4.2 R01221,R03425
Swm_02290 aminomethyl-transferring glycine dehydrogenase subunit GcvPA K00282 gcvPA 1.4.4.2 R01221,R03425
Swm_02291 glycine cleavage system protein GcvH K02437 gcvH, GCSH — R01221
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