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◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_CM128632.1:410,770–416,915

Syntrophomonas erecta DSM 16215 · 6 genes
6
genes
6
KO-annotated
14
reactions
5
pathways

Activity by pathway — click to expand; ranked by genes involved

Aminoacyl-tRNA biosynthesisGenetic Information Processing; Translation3 genes · 6 rxns
Ser_00372 K02435 gatC, GATC R03905
Glutaminyl-tRNA + L-Glutamate + Orthophosphate + ADP <=> L-Glutamyl-tRNA(Gln) + L-Glutamine + ATP + H2O
Glu-tRNA(Gln):L-glutamine amido-ligase (ADP-forming)
Ser_00372 K02435 gatC, GATC R04212
L-Asparaginyl-tRNA(Asn) + L-Glutamate + Orthophosphate + ADP <=> L-Aspartyl-tRNA(Asn) + L-Glutamine + ATP + H2O
Asp-tRNA(Asn):L-glutamine amido-ligase (ADP-forming)
Ser_00373 K02433 gatA, QRSL1 R03905
Glutaminyl-tRNA + L-Glutamate + Orthophosphate + ADP <=> L-Glutamyl-tRNA(Gln) + L-Glutamine + ATP + H2O
Glu-tRNA(Gln):L-glutamine amido-ligase (ADP-forming)
Ser_00373 K02433 gatA, QRSL1 R04212
L-Asparaginyl-tRNA(Asn) + L-Glutamate + Orthophosphate + ADP <=> L-Aspartyl-tRNA(Asn) + L-Glutamine + ATP + H2O
Asp-tRNA(Asn):L-glutamine amido-ligase (ADP-forming)
Ser_00374 K02434 gatB, PET112 R03905
Glutaminyl-tRNA + L-Glutamate + Orthophosphate + ADP <=> L-Glutamyl-tRNA(Gln) + L-Glutamine + ATP + H2O
Glu-tRNA(Gln):L-glutamine amido-ligase (ADP-forming)
Ser_00374 K02434 gatB, PET112 R04212
L-Asparaginyl-tRNA(Asn) + L-Glutamate + Orthophosphate + ADP <=> L-Aspartyl-tRNA(Asn) + L-Glutamine + ATP + H2O
Asp-tRNA(Asn):L-glutamine amido-ligase (ADP-forming)
Valine, leucine and isoleucine biosynthesisMetabolism; Amino acid metabolism2 genes · 16 rxns
Ser_00376 K01703 leuC, IPMI-L R03896
(R)-2-Methylmalate <=> 2-Methylmaleate + H2O
(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)
Ser_00376 K01703 leuC, IPMI-L R03898
2-Methylmaleate + H2O <=> D-erythro-3-Methylmalate
2-methylmaleate hydratase; D-erythro-3-methylmalate hydro-lyase (2-methylmaleate-forming)
Ser_00376 K01703 leuC, IPMI-L R03968
alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O
2-isopropylmalate hydro-lyase
Ser_00376 K01703 leuC, IPMI-L R04001
(2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
3-isopropylmalate hydro-lyase
Ser_00376 K01703 leuC, IPMI-L R08620
2-(2'-Methylthio)ethylmalic acid <=> 3-(2'-Methylthio)ethylmalic acid
2-(2'-methylthio)ethylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08624
2-(3'-Methylthio)propylmalic acid <=> 3-(3'-Methylthio)propylmalic acid
2-(3'-methylthio)propylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08628
2-(4'-Methylthio)butylmalic acid <=> 3-(4'-Methylthio)butylmalic acid
2-(3'-methylthio)butylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08634
2-(5'-Methylthio)pentylmalic acid <=> 3-(5'-Methylthio)pentylmalic acid
2-(3'-methylthio)pentylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08641
2-(6'-Methylthio)hexylmalic acid <=> 3-(6'-Methylthio)hexylmalic acid
2-(3'-methylthio)hexylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08645
2-(7'-Methylthio)heptylmalic acid <=> 3-(7'-Methylthio)heptylmalic acid
2-(3'-methylthio)heptylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R10170
(2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate
(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)
Ser_00377 K01704 leuD, IPMI-S R03896
(R)-2-Methylmalate <=> 2-Methylmaleate + H2O
(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)
Ser_00377 K01704 leuD, IPMI-S R03898
2-Methylmaleate + H2O <=> D-erythro-3-Methylmalate
2-methylmaleate hydratase; D-erythro-3-methylmalate hydro-lyase (2-methylmaleate-forming)
Ser_00377 K01704 leuD, IPMI-S R03968
alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O
2-isopropylmalate hydro-lyase
Ser_00377 K01704 leuD, IPMI-S R04001
(2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
3-isopropylmalate hydro-lyase
Ser_00377 K01704 leuD, IPMI-S R10170
(2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate
(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)
C5-Branched dibasic acid metabolismMetabolism; Carbohydrate metabolism2 genes · 16 rxns
Ser_00376 K01703 leuC, IPMI-L R03896
(R)-2-Methylmalate <=> 2-Methylmaleate + H2O
(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)
Ser_00376 K01703 leuC, IPMI-L R03898
2-Methylmaleate + H2O <=> D-erythro-3-Methylmalate
2-methylmaleate hydratase; D-erythro-3-methylmalate hydro-lyase (2-methylmaleate-forming)
Ser_00376 K01703 leuC, IPMI-L R03968
alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O
2-isopropylmalate hydro-lyase
Ser_00376 K01703 leuC, IPMI-L R04001
(2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
3-isopropylmalate hydro-lyase
Ser_00376 K01703 leuC, IPMI-L R08620
2-(2'-Methylthio)ethylmalic acid <=> 3-(2'-Methylthio)ethylmalic acid
2-(2'-methylthio)ethylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08624
2-(3'-Methylthio)propylmalic acid <=> 3-(3'-Methylthio)propylmalic acid
2-(3'-methylthio)propylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08628
2-(4'-Methylthio)butylmalic acid <=> 3-(4'-Methylthio)butylmalic acid
2-(3'-methylthio)butylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08634
2-(5'-Methylthio)pentylmalic acid <=> 3-(5'-Methylthio)pentylmalic acid
2-(3'-methylthio)pentylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08641
2-(6'-Methylthio)hexylmalic acid <=> 3-(6'-Methylthio)hexylmalic acid
2-(3'-methylthio)hexylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08645
2-(7'-Methylthio)heptylmalic acid <=> 3-(7'-Methylthio)heptylmalic acid
2-(3'-methylthio)heptylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R10170
(2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate
(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)
Ser_00377 K01704 leuD, IPMI-S R03896
(R)-2-Methylmalate <=> 2-Methylmaleate + H2O
(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)
Ser_00377 K01704 leuD, IPMI-S R03898
2-Methylmaleate + H2O <=> D-erythro-3-Methylmalate
2-methylmaleate hydratase; D-erythro-3-methylmalate hydro-lyase (2-methylmaleate-forming)
Ser_00377 K01704 leuD, IPMI-S R03968
alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O
2-isopropylmalate hydro-lyase
Ser_00377 K01704 leuD, IPMI-S R04001
(2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
3-isopropylmalate hydro-lyase
Ser_00377 K01704 leuD, IPMI-S R10170
(2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate
(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)
Pyruvate metabolismMetabolism; Carbohydrate metabolism1 genes · 1 rxns
Ser_00375 K02594 nifV R00271
Acetyl-CoA + H2O + 2-Oxoglutarate <=> (R)-2-Hydroxybutane-1,2,4-tricarboxylate + CoA
acetyl-CoA:2-oxoglutarate C-acetyltransferase (thioester-hydrolysing, carboxymethyl forming)
Glucosinolate biosynthesisMetabolism; Biosynthesis of other secondary metabolites1 genes · 11 rxns
Ser_00376 K01703 leuC, IPMI-L R03896
(R)-2-Methylmalate <=> 2-Methylmaleate + H2O
(R)-2-methylmalate hydro-lyase (2-methylmaleate-forming)
Ser_00376 K01703 leuC, IPMI-L R03898
2-Methylmaleate + H2O <=> D-erythro-3-Methylmalate
2-methylmaleate hydratase; D-erythro-3-methylmalate hydro-lyase (2-methylmaleate-forming)
Ser_00376 K01703 leuC, IPMI-L R03968
alpha-Isopropylmalate <=> 2-Isopropylmaleate + H2O
2-isopropylmalate hydro-lyase
Ser_00376 K01703 leuC, IPMI-L R04001
(2R,3S)-3-Isopropylmalate <=> 2-Isopropylmaleate + H2O
3-isopropylmalate hydro-lyase
Ser_00376 K01703 leuC, IPMI-L R08620
2-(2'-Methylthio)ethylmalic acid <=> 3-(2'-Methylthio)ethylmalic acid
2-(2'-methylthio)ethylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08624
2-(3'-Methylthio)propylmalic acid <=> 3-(3'-Methylthio)propylmalic acid
2-(3'-methylthio)propylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08628
2-(4'-Methylthio)butylmalic acid <=> 3-(4'-Methylthio)butylmalic acid
2-(3'-methylthio)butylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08634
2-(5'-Methylthio)pentylmalic acid <=> 3-(5'-Methylthio)pentylmalic acid
2-(3'-methylthio)pentylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08641
2-(6'-Methylthio)hexylmalic acid <=> 3-(6'-Methylthio)hexylmalic acid
2-(3'-methylthio)hexylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R08645
2-(7'-Methylthio)heptylmalic acid <=> 3-(7'-Methylthio)heptylmalic acid
2-(3'-methylthio)heptylmalate hydroxymutase
Ser_00376 K01703 leuC, IPMI-L R10170
(2R,3S)-3-Isopropylmalate <=> alpha-Isopropylmalate
(2R,3S)-3-isopropylmalate hydro-lyase (2-isopropylmaleate-forming)

Overview / global maps (every metabolic gene maps here)

Metabolic pathways 5 genes
Ser_00372 Ser_00373 Ser_00374 Ser_00376 Ser_00377
Biosynthesis of secondary metabolites 2 genes
Ser_00376 Ser_00377
2-Oxocarboxylic acid metabolism 2 genes
Ser_00376 Ser_00377
Biosynthesis of amino acids 2 genes
Ser_00376 Ser_00377

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Ser_00372 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC K02435 gatC, GATC 6.3.5.6,6.3.5.7 R03905,R04212
Ser_00373 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA K02433 gatA, QRSL1 6.3.5.6,6.3.5.7 R03905,R04212
Ser_00374 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB K02434 gatB, PET112 6.3.5.6,6.3.5.7 R03905,R04212
Ser_00375 homocitrate synthase K02594 nifV 2.3.3.14 R00271
Ser_00376 3-isopropylmalate dehydratase large subunit K01703 leuC, IPMI-L 4.2.1.33,4.2.1.35 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170
Ser_00377 3-isopropylmalate dehydratase small subunit K01704 leuD, IPMI-S 4.2.1.33,4.2.1.35 R03896,R03898,R03968,R04001,R10170
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