Reaction Activity

Operon NZ_CM128632.1:1,428,288–1,430,608

Syntrophomonas erecta DSM 16215 · 3 genes

genes

KO-annotated

reactions

pathways

Mismatch repairGenetic Information Processing; Replication and repair2 genes · 0 rxns

Ser_01279 K03602 xseB

Ser_01280 K03601 xseA

One carbon pool by folateMetabolism; Metabolism of cofactors and vitamins1 genes · 2 rxns

Ser_01281 K01491 folD R01220

5,10-Methylenetetrahydrofolate + NADP+ <=> 5,10-Methenyltetrahydrofolate + NADPH

5,10-methylenetetrahydrofolate:NADP+ oxidoreductase

Ser_01281 K01491 folD R01655

5,10-Methenyltetrahydrofolate + H2O <=> 10-Formyltetrahydrofolate + H+

5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing)

Other carbon fixation pathwaysMetabolism; Energy metabolism1 genes · 2 rxns

Ser_01281 K01491 folD R01220

5,10-Methylenetetrahydrofolate + NADP+ <=> 5,10-Methenyltetrahydrofolate + NADPH

5,10-methylenetetrahydrofolate:NADP+ oxidoreductase

Ser_01281 K01491 folD R01655

5,10-Methenyltetrahydrofolate + H2O <=> 10-Formyltetrahydrofolate + H+

5,10-methenyltetrahydrofolate 5-hydrolase (decyclizing)

Metabolic pathways 1 genes

Ser_01281

Microbial metabolism in diverse environments 1 genes

Ser_01281

Carbon metabolism 1 genes

Ser_01281

show cofactors (H₂O, ATP, NAD⁺…) drag nodes · click an edge for the reaction

Locus	Product	KO	EC	Reactions
Ser_01279	exodeoxyribonuclease VII small subunit	K03602 xseB	3.1.11.6	—
Ser_01280	exodeoxyribonuclease VII large subunit	K03601 xseA	3.1.11.6	—
Ser_01281	bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase	K01491 folD	1.5.1.5,3.5.4.9	R01220,R01655