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◀ domain architecture  ·  operons  ·  ❔ guide

Operon NZ_BBCE01000003.1:88,969–91,402

Syntrophomonas palmitatica JCM14374 Spalm · 4 genes
4
genes
3
KO-annotated
4
reactions
5
pathways

Activity by pathway — click to expand; ranked by genes involved

Non-homologous end-joiningGenetic Information Processing; Replication and repair3 genes · 4 rxns
Spalm_00520 K10979 ku
Spalm_00521 K10979 ku
Spalm_00522 K01971 ligD R00381
ATP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Diphosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming)
Spalm_00522 K01971 ligD R00382
NAD+ + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Nicotinamide D-ribonucleotide + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming, NMN-forming)
Spalm_00522 K01971 ligD R10822
ADP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Orthophosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (ADP)
Spalm_00522 K01971 ligD R10823
GTP + DNA(n) + 5'-Phospho-DNA(m) <=> GMP + Diphosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (GTP)
DNA replicationGenetic Information Processing; Replication and repair1 genes · 4 rxns
Spalm_00522 K01971 ligD R00381
ATP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Diphosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming)
Spalm_00522 K01971 ligD R00382
NAD+ + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Nicotinamide D-ribonucleotide + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming, NMN-forming)
Spalm_00522 K01971 ligD R10822
ADP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Orthophosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (ADP)
Spalm_00522 K01971 ligD R10823
GTP + DNA(n) + 5'-Phospho-DNA(m) <=> GMP + Diphosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (GTP)
Base excision repairGenetic Information Processing; Replication and repair1 genes · 4 rxns
Spalm_00522 K01971 ligD R00381
ATP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Diphosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming)
Spalm_00522 K01971 ligD R00382
NAD+ + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Nicotinamide D-ribonucleotide + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming, NMN-forming)
Spalm_00522 K01971 ligD R10822
ADP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Orthophosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (ADP)
Spalm_00522 K01971 ligD R10823
GTP + DNA(n) + 5'-Phospho-DNA(m) <=> GMP + Diphosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (GTP)
Nucleotide excision repairGenetic Information Processing; Replication and repair1 genes · 4 rxns
Spalm_00522 K01971 ligD R00381
ATP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Diphosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming)
Spalm_00522 K01971 ligD R00382
NAD+ + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Nicotinamide D-ribonucleotide + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming, NMN-forming)
Spalm_00522 K01971 ligD R10822
ADP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Orthophosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (ADP)
Spalm_00522 K01971 ligD R10823
GTP + DNA(n) + 5'-Phospho-DNA(m) <=> GMP + Diphosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (GTP)
Mismatch repairGenetic Information Processing; Replication and repair1 genes · 4 rxns
Spalm_00522 K01971 ligD R00381
ATP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Diphosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming)
Spalm_00522 K01971 ligD R00382
NAD+ + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Nicotinamide D-ribonucleotide + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (AMP-forming, NMN-forming)
Spalm_00522 K01971 ligD R10822
ADP + DNA(n) + 5'-Phospho-DNA(m) <=> AMP + Orthophosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (ADP)
Spalm_00522 K01971 ligD R10823
GTP + DNA(n) + 5'-Phospho-DNA(m) <=> GMP + Diphosphate + DNA(n+m)
(deoxyribonucleotide)n:5'-phospho-(deoxyribonucleotide)m ligase (GTP)

Reaction network — compounds linked by the reactions these genes catalyse

drag nodes · click an edge for the reaction

Genes

LocusProductKOECReactions
Spalm_00519 DUF4013 domain-containing protein — — —
Spalm_00520 non-homologous end joining protein Ku K10979 ku — —
Spalm_00521 Ku protein K10979 ku — —
Spalm_00522 non-homologous end-joining DNA ligase K01971 ligD; K10747 LIG1 6.5.1.1,6.5.1.6,6.5.1.7 R00381,R00382,R10822,R10823
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