Gene / Protein

Small Microbes Pathway Profiler

Profiler Search and BLAST

◀ domain architecture · operons · ❔ guide

Swm_02038

smpp Syntrophomonas wolfei methylbutyratica 4J5

operons in this genome ▶ · domain architectures ▶ · reaction activity ▶

✕

Identity & position

Product: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
Gene: hisA
Location: NZ_CM161534.1:2,243,069–2,243,797 (−) 242 aa
Keys: gbid 939250 gene_oid 8108584238

Domain architecture

Pfam domain

Pfam signature: pfam00977

Putative operon (same contig + strand, gap ≤ 50 bp)

Swm_02036 Swm_02037 Swm_02038 ◀ → reaction activity for this operon

Same architecture across genomes — proteins sharing this exact Pfam-domain signature

14 proteins across 8 genomes share architecture group #1028 pfam00977

Genome	Locus	aa	SP/TM	Pfam order
Syntrophomonas wolfei methylbutyratica 4J5	Swm_02037	252		pfam00977
Syntrophomonas wolfei methylbutyratica 4J5	Swm_02038 ◀	242		pfam00977
Syntrophomonas curvata DSM15682 / GL#14	Scur_02304	253		pfam00977
Syntrophomonas curvata DSM15682 / GL#14	Scur_02305	243		pfam00977
Syntrophomonas erecta DSM 16215 / GB-438	Ser_00189	241		pfam00977
Syntrophomonas erecta sporosyntropha Sespor / JCM 13344	Sesp_00582	241		pfam00977
Syntrophomonas palmitatica JCM14374 Spalm	Spalm_00147	254		pfam00977
Syntrophomonas palmitatica JCM14374 Spalm	Spalm_00148	247		pfam00977
Syntrophomonas palmitatica JCM14374 Spalm	Spalm_00799	260		pfam00977
Syntrophomonas wolfei saponavida / SD2	Sws_01841	244		pfam00977
Syntrophomonas wolfei saponavida / SD2	Sws_01842	254		pfam00977
Syntrophomonas wolfei subsp. wolfei Goettingen	Swg_01799	244		pfam00977
Syntrophomonas zehnderi OL-4 Szehn	Szeh_02489	244		pfam00977
Syntrophomonas zehnderi OL-4 Szehn	Szeh_02490	261		pfam00977

↑ Top

v1.00 @copyright 2026 UCLA